Dr Cecile Lefoulon

  • Research Technician (Institute of Molecular Cell & Systems Biology)

Biography

Key Skills 

Grant Funded

I'm specialised in electrophysiology, in both plant and Xemopus oocyte. I'm working with plants but I also use oocyte which is a great system to express any transporter to assess its function. I can take in charge the experimental setting from the cloning to the transporter function analysing. 

  • Electrophysiology: Voltage Clamp in Xenopus oocytes, in plant cell and Patch clamp. 
  • Molecular biology: Cloning, site mutagenesis, miniprep, in-vitro transcription 
  • Confocal imaging 

Research interests

I'm interested in Plant cell physiology especially in membrane transport regulation (Pump/channels). I can extend my work on other organisms (for example I recently worked with a pump from halobacteria). 


Publications

List by: Type | Date

Jump to: 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014
Number of items: 8.

2020

Lefoulon, C., Boxall, S. F., Hartwell, J. and Blatt, M. R. (2020) CAM guard cell anion channel activity follows transcript abundance and is suppressed by apoplastic malate. New Phytologist, (doi: 10.1111/nph.16640) (Early Online Publication)

2019

Waghmare, S., Lefoulon, C., Zhang, B. , Lileikyte, E., Donald, N. and Blatt, M. (2019) K+ channel and SEC11 binding exchange regulates SNARE assembly for secretory traffic. Plant Physiology, 181, pp. 1096-1113. (doi: 10.1104/pp.19.00919) (PMID:31548266)

2018

Lefoulon, C., Waghmare, S., Karnik, R. and Blatt, M. R. (2018) Gating control and K+ uptake by the KAT1 K+ channel leaveraged through membrane anchoring of the trafficking protein SYP121. Plant, Cell and Environment, 41(11), pp. 2668-2677. (doi: 10.1111/pce.13392) (PMID:29940699) (PMCID:PMC6220998)

Feroz, H. et al. (2018) Light-driven chloride transport kinetics of halorhodopsin. Biophysical Journal, 115(2), pp. 353-360. (doi: 10.1016/j.bpj.2018.06.009) (PMID:30021110)

2017

Karnik, R. , Waghmare, S., Zhang, B. , Larson, E., Lefoulon, C., Gonzalez, W. and Blatt, M. R. (2017) Commandeering channel voltage sensors for secretion, cell turgor, and volume control. Trends in Plant Science, 22(1), pp. 81-95. (doi: 10.1016/j.tplants.2016.10.006) (PMID:27818003) (PMCID:PMC5224186)

2016

Lefoulon, C., Boeglin, M., Moreau, B., Véry, A.-A., Szponarski, W., Dauzat, M., Michard, E., Gaillard, I. and Chérel, I. (2016) The Arabidopsis AtPP2CA protein phosphatase inhibits the GORK K+ efflux channel and exerts a dominant suppressive effect on phosphomimetic-activating mutations. Journal of Biological Chemistry, 291(12), pp. 6521-6533. (doi: 10.1074/jbc.M115.711309) (PMID:26801610)

2015

Grefen, C., Karnik, R. , Larson, E., Lefoulon, C., Wang, Y., Waghmare, S., Zhang, B. , Hills, A. and Blatt, M. R. (2015) A vesicle-trafficking protein commandeers Kv channel voltage sensors for voltage-dependent secretion. Nature Plants, 1, 15108. (doi: 10.1038/nplants.2015.108)

2014

Lefoulon, C., Karnik, R. , Honsbein, A., Gutla, P. V., Grefen, C., Riedelsberger, J., Poblete, T., Dreyer, I., Gonzalez, W. and Blatt, M. R. (2014) Voltage-sensor transitions of the inward-rectifying K+ channel KAT1 indicate a latching mechanism biased by hydration within the voltage sensor. Plant Physiology, 166(2), pp. 960-975. (doi: 10.1104/pp.114.244319) (PMID:25185120)

This list was generated on Wed Jul 8 16:05:33 2020 BST.
Jump to: Articles
Number of items: 8.

Articles

Lefoulon, C., Boxall, S. F., Hartwell, J. and Blatt, M. R. (2020) CAM guard cell anion channel activity follows transcript abundance and is suppressed by apoplastic malate. New Phytologist, (doi: 10.1111/nph.16640) (Early Online Publication)

Waghmare, S., Lefoulon, C., Zhang, B. , Lileikyte, E., Donald, N. and Blatt, M. (2019) K+ channel and SEC11 binding exchange regulates SNARE assembly for secretory traffic. Plant Physiology, 181, pp. 1096-1113. (doi: 10.1104/pp.19.00919) (PMID:31548266)

Lefoulon, C., Waghmare, S., Karnik, R. and Blatt, M. R. (2018) Gating control and K+ uptake by the KAT1 K+ channel leaveraged through membrane anchoring of the trafficking protein SYP121. Plant, Cell and Environment, 41(11), pp. 2668-2677. (doi: 10.1111/pce.13392) (PMID:29940699) (PMCID:PMC6220998)

Feroz, H. et al. (2018) Light-driven chloride transport kinetics of halorhodopsin. Biophysical Journal, 115(2), pp. 353-360. (doi: 10.1016/j.bpj.2018.06.009) (PMID:30021110)

Karnik, R. , Waghmare, S., Zhang, B. , Larson, E., Lefoulon, C., Gonzalez, W. and Blatt, M. R. (2017) Commandeering channel voltage sensors for secretion, cell turgor, and volume control. Trends in Plant Science, 22(1), pp. 81-95. (doi: 10.1016/j.tplants.2016.10.006) (PMID:27818003) (PMCID:PMC5224186)

Lefoulon, C., Boeglin, M., Moreau, B., Véry, A.-A., Szponarski, W., Dauzat, M., Michard, E., Gaillard, I. and Chérel, I. (2016) The Arabidopsis AtPP2CA protein phosphatase inhibits the GORK K+ efflux channel and exerts a dominant suppressive effect on phosphomimetic-activating mutations. Journal of Biological Chemistry, 291(12), pp. 6521-6533. (doi: 10.1074/jbc.M115.711309) (PMID:26801610)

Grefen, C., Karnik, R. , Larson, E., Lefoulon, C., Wang, Y., Waghmare, S., Zhang, B. , Hills, A. and Blatt, M. R. (2015) A vesicle-trafficking protein commandeers Kv channel voltage sensors for voltage-dependent secretion. Nature Plants, 1, 15108. (doi: 10.1038/nplants.2015.108)

Lefoulon, C., Karnik, R. , Honsbein, A., Gutla, P. V., Grefen, C., Riedelsberger, J., Poblete, T., Dreyer, I., Gonzalez, W. and Blatt, M. R. (2014) Voltage-sensor transitions of the inward-rectifying K+ channel KAT1 indicate a latching mechanism biased by hydration within the voltage sensor. Plant Physiology, 166(2), pp. 960-975. (doi: 10.1104/pp.114.244319) (PMID:25185120)

This list was generated on Wed Jul 8 16:05:33 2020 BST.