Professor Tony Page

  • Professor of Molecular and Biochemical Parasitology (Institute of Biodiversity Animal Health & Comparative Medicine)
  • Associate (Institute of Infection Immunity & Inflammation)
  • Associate (School of Veterinary Medicine)

Research interests

Google Scholar - Publications Profile

Nematode development and genetics: Applying Caenorhabditis elegans as a model system to study nematode parasites and develop novel antihelminthics. C. elegans as a model system to study extracellular matrix formation, redox balance in the ER, protein folding and ageing. 


Grants

Grants and Awards listed are those received whilst working with the University of Glasgow.

  • Resistance in Agriculture: Investigation of Anthelmintic Drug Uptake and Resistance Mechanisms in Gastrointestinal Nematode Parasites of Livestock
    Biotechnology and Biological Sciences Research Council
    2018 - 2021
     
  • Shedding light on oxidative stress: Identifying factors modulating the redox balance in the endoplasmic reticulum of Caenorhabditis elegans.
    Biotechnology and Biological Sciences Research Council
    2013 - 2016
     
  • Identifying factors modulating the redox balance in the endoplasmic reticulum using the model system Carnorhabditis elegans (ISSF Catalyst Fund)
    Wellcome Trust
    2011 - 2014
     
  • The matrix associated astacin enzymes; novel targets in the control of key GI nematodes of ruminants.
    Biotechnology and Biological Sciences Research Council
    2011 - 2015
     
  • Chemical mapping of the PPIase interactome in C elegans - development of a systems biology toolbox
    Biotechnology and Biological Sciences Research Council
    2006 - 2009
     
  • Moulting and hatching in nematodes - the role of astacin metalloproteases as potential anti-nematode targets
    Biotechnology and Biological Sciences Research Council
    2006 - 2009
     
  • Molecular genetics and biochemistry of parasites
    Medical Research Council
    2004 - 2009
     
  • The Molecular Enzymology of Collagen Assembly and Post-Translational Modification: a Nematode Model System
    Medical Research Council
    2003 - 2008
     

Research datasets

Additional information

Grant Advisory Board

  • 2005 - 2009: MRC - Training and Career Development Board
  • 2004 - present: MRC - College of Experts, Infection and Immunity

Invited International Presentations

  • 2008: Hydra, Greece - Molecular Helminthology
  • 2008: Seville, Spain - European C. elegans Meeting
  • 2005: Hydra, Greece - Molecular Helminthology
  • 2005: Oulu, Finland - C. elegans Symposium and workshop
  • 2005: Nottingham, UK - British Society of Parasitology
  • 2003: New Hampshire, USA - Gordon Collagen Conference

Prizes, Awards and Distinctions

  • 1994: MRC - Career Development Award

Research Fellowship

  • 2003 - 2008: MRC Senior Non-clinical Fellowship
  • 1998 - 2003: MRC Senior Non-clinical Fellowship

Publications

List by: Type | Date

Jump to: 2019 | 2018 | 2015 | 2014 | 2013 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006 | 2004 | 2003 | 2002
Number of items: 39.

2019

Page, A. P. , Roberts, M., Felix, M.-A., Pickard, D., Page, A. and Weir, W. (2019) The golden death bacillus Chryseobacterium nematophagum is a novel matrix digesting pathogen of nematodes. BMC Biology, 17, 10. (doi:10.1186/s12915-019-0632-x) (PMID:30813925) (PMCID:PMC6394051)

2018

Robertson, E., Harcus, Y., Johnston, C. J.C., Page, A. P. , Walkinshaw, M. D., Maizels, R. M. and Houston, D. (2018) Demonstration of the anthelmintic potency of marimastat in the Heligmosomoides polygyrus rodent model. Journal of Parasitology, 104(6), pp. 705-709. (doi:10.1645/18-33) (PMID:30085900)

Page, A. P. (2018) The sensory amphidial structures of Caenorhabditis elegans are involved in macrocyclic lactone uptake and anthelmintic resistance. International Journal for Parasitology, 48(13), pp. 1035-1042. (doi:10.1016/j.ijpara.2018.06.003) (PMID:30253131) (PMCID:PMC6237615)

2015

France, D. J. , Stepek, G., Houston, D. R., Williams, L., McCormack, G., Walkinshaw, M. D. and Page, A. P. (2015) Identification and activity of inhibitors of the essential nematode-specific metalloprotease DPY-31. Bioorganic and Medicinal Chemistry Letters, (doi:10.1016/j.bmcl.2015.10.077) (PMID:26546217)

Stepek, G., McCormack, G., Winter, A. D. and Page, A. P. (2015) A highly conserved, inhibitable astacin metalloprotease from Teladorsagia circumcincta is required for cuticle formation and nematode development. International Journal for Parasitology, 45(3), pp. 345-355. (doi:10.1016/j.ijpara.2015.01.004) (PMID:25736599) (PMCID:PMC4406453)

2014

Page, A. P. , Stepek, G., Winter, A. D. and Pertab, D. (2014) Enzymology of the nematode cuticle: a potential drug target? International Journal for Parasitology: Drugs and Drug Resistance, 4(2), pp. 133-141. (doi:10.1016/j.ijpddr.2014.05.003) (PMID:25057463) (PMCID:PMC4095051)

2013

Winter, A., McCormack, G., Myllyharju, J. and Page, A. (2013) Prolyl 4-hydroxlase activity is essential for development and cuticle formation in the human infective parasitic nematode Brugia malayi. Journal of Biological Chemistry, 288(3), pp. 1750-1761. (doi:10.1074/jbc.M112.397604)

Page, A.P. (2013) The nematode cuticle: synthesis, modification and turnover. In: Kennedy, M.W. and Harnett, W. (eds.) Parasitic Nematodes: Molecular Biology, Biochemistry and Immunology. Cabi Publishing, pp. 337-350. ISBN 9781845937591 (doi:10.1079/9781845937591.0337)

2011

Dunsmore, C.J., Malone, K.J., Bailey, K.R., Wear, M.A., Florance, H., Shirran, S., Barran, P.E., Page, A.P. , Walkinshaw, M.D. and Turner, N.J. (2011) Design and Synthesis of Conformationally Constrained Cyclophilin Inhibitors Showing a Cyclosporin-A Phenotype in C. elegans. ChemBioChem, 12(5), pp. 802-810. (doi:10.1002/cbic.201000413)

Stepek, G., McCormack, G., Birnie, A.J. and Page, A.P. (2011) The astacin metalloprotease moulting enzyme NAS-36 is required for normal cuticle ecdysis in free-living and parasitic nematodes. Parasitology, 138(2), pp. 237-248. (doi:10.1017/S0031182010001113)

2010

Stepek, G., McCormack, G. and Page, A. P. (2010) Collagen processing and cuticle formation is catalysed by the astacin metalloprotease DPY-31 in free-living and parasitic nematodes. International Journal for Parasitology, 40(5), pp. 533-542. (doi:10.1016/j.ijpara.2009.10.007)

Stepek, G., McCormack, G. and Page, A. P. (2010) The kunitz domain protein BLI-5 plays a functionally conserved role in cuticle formation in a diverse range of nematodes. Molecular and Biochemical Parasitology, 169(1), pp. 1-11. (doi:10.1016/j.molbiopara.2009.08.005)

Husi, H. et al. (2010) Selective Chemical Intervention in the Proteome ofCaenorhabditis elegans. Journal of Proteome Research, 9(11), pp. 6060-6070. (doi:10.1021/pr100427c)

2009

Thein, M. C., Winter, A. D., Stepek, G., McCormack, G., Stapleton, G., Johnstone, I. L. and Page, A. P. (2009) Combined extracellular matrix cross-linking activity of the peroxidase MLT-7 and the dual oxidase BLI-3 is critical for post-embryonic viability in Caenorhabditis elegans. Journal of Biological Chemistry, 284(26), pp. 17549-17563. (doi:10.1074/jbc.M900831200)

2008

Callister, D. M., Winter, A. D., Page, A. P. and Maizels, R. M. (2008) Four abundant novel transcript genes from Toxocara canis with unrelated coding sequences share untranslated region tracts implicated in the control of gene expression. Molecular and Biochemical Parasitology, 162(1), pp. 60-70. (doi:10.1016/j.molbiopara.2008.07.004)

Keskiaho, K., Kukkola, L., Page, A. P. , Winter, A. D., Vuoristo, J., Sormunen, R., Nissi, R., Riihimaa, P. and Myllyharju, J. (2008) Characterization of a novel Caenorhabditis elegans prolyl 4-hydroxylase with a unique substrate specificity and restricted expression in the pharynx and excretory duct. Journal of Biological Chemistry, 283(16), pp. 10679-10689. (doi:10.1074/jbc.M800972200)

Worrall, L. J., Wear, M. A., Page, A. P. and Walkinshaw, M. D. (2008) Cloning, purification and characterization of the Caenorhabditis elegans small glutamine-rich tetratricopeptide repeat-containing protein. Biochimica et Biophysica Acta: Proteins and Proteomics, 1784(3), pp. 496-503. (doi:10.1016/j.bbapap.2007.12.003) (PMID:18187053)

2007

Yang, Y., Moir, E., Kontopidis, G., Taylor, P., Wear, M. A., Malone, K., Dunsmore, C. J., Page, A. P., Turner, N. J. and Walkinshaw, M. D. (2007) Structure-based discovery of a family of synthetic cyclophilin inhibitors showing a cyclosporin-A phenotype in Caenorhabditis elegans. Biochemical and Biophysical Research Communications, 363(4), pp. 1013-1019. (doi:10.1016/j.bbrc.2007.09.079)

Winter, A. D., McCormack, G. and Page, A. P. (2007) Protein disulfide isomerase activity is essential for viability and extracellular matrix formation in the nematode Caenorhabditis elegans. Developmental Biology, 308(2), pp. 449-461. (doi:10.1016/j.ydbio.2007.05.041)

Winter, A. D., Keskiaho, K., Kukkalo, L., McCormack, G., Felix, M.-A., Myllyharju, J. and Page, A. P. (2007) Differences in collagen prolyl 4-hydroxylase assembly between two Caenorhabditis nematode species despite high amino acid sequence identity of the enzyme subunits. Matrix Biology, 26(5), pp. 382-395. (doi:10.1016/j.matbio.2007.01.008)

Winter, A. D., Eschenlauer, S. C. P., McCormack, G. and Page, A. P. (2007) Loss of secretory pathway FK506-binding proteins results in cold-sensitive lethality in caenorhabditis elegans. Journal of Biological Chemistry, 282(17), pp. 12813-12821. (doi:10.1074/jbc.M700274200)

Page, A. P. and Johnstone, I. J. (2007) The cuticle. In: Kramer, J. M. and Moerman, D. G. (eds.) Wormbook. The C. elegans Research Community: http://www.wormbook.org.

Richardson, J., Dornan, J., Opamawutthikul, M., Bruce, S., Page, A. and Walkinshaw, M. (2007) Cloning, expression and characterisation of FKB-6, the sole large TPR-containing immunophilin from C-elegans. Biochemical and Biophysical Research Communications, 360, pp. 566-572. (doi:10.1016/j.bbrc.2007.06.080)

Winter, A., Eschenlauer, S., McCormack, G. and Page, A. (2007) Loss of secretory pathway FK506-binding proteins results in cold-sensitive lethality and associate extracellular matrix defects in the nematode Caenorhabditis elegans. Journal of Biological Chemistry, 282, pp. 12813-12821. (doi:10.1074/jbc.M700274200)

Winter, A., McCormack, G. and Page, A. (2007) Protein disulfide isomerase activity is essential for viability and extracellular matrix formation in the nematode Caenorhabditis elegans. Developmental Biology, 308, pp. 449-461. (doi:10.1016/j.ydbio.2007.05.041)

2006

Bell, A., Monaghan, P. and Page, A. (2006) Peptidyl-prolyl cis-trans isomerases (immunophilins) and their roles in parasite biochemistry, host-parasite interaction and antiparasitic drug action. International Journal for Parasitology, 36(3), pp. 261-276. (doi:10.1016/j.ijpara.2005.11.003)

Bell, A., Monaghan, P. and Page, A.P. (2006) Peptidyl-prolyl cis-trans isomerases (immunophilins) and their roles in parasite biochemistry, host-parasite interaction and antiparasitic drug action. International Journal for Parasitology, 36(3), pp. 261-276. (doi:10.1016/j.ijpara.2005.11.003)

Novelli, J., Page, A. and Hodgkin, J. (2006) The C terminus of collagen SQT-3 has complex and essential functions in nematode collagen assembly. Genetics, 172, pp. 2253-2267. (doi:10.1534/genetics.105.053637)

Page, A. P. , McCormack, G. and Birnie, A. J. (2006) Biosynthesis and enzymology of the Caenorhabditis elegans cuticle: identification and characterization of a novel serine protease inhibitor. International Journal for Parasitology, 36(6), pp. 681-689. (doi:10.1016/j.ijpara.2006.01.004)

2004

Davis, M.W., Birnie, A.J., Chan, A.C., Page, A.P. and Jorgensen, A.M. (2004) A conserved metalloprotease mediates ecdysis in Caenorhabditis elegans. Development, 131, pp. 6001-6008. (doi:10.1242/dev.01454)

Davis, M., Birnie, A., Chan, A., Page, A. and Jorgensen, E. (2004) A conserved metalloprotease mediates ecdysis in Caenorhabditis elegans. Development, 131, pp. 6001-6008. (doi:10.1242/dev.01454)

Kukkola, L., Koivunen, P., Pakkanen, O., Page, A. and Myllyharju, J. (2004) Collagen prolyl 4-hydroxylase tetramers and dimers show identical decreases in K-m values for peptide substrates with increasing chain length - Mutation of one of the two catalytic sites in the tetramer inactivates the enzyme by more than half. Journal of Biological Chemistry, 279, pp. 18656-18661. (doi:10.1074/jbc.M401514200)

2003

Eschenlauer, S. and Page, A. (2003) The Caenorhabditis elegans ERp60 homolog protein disulfide isomerase-3 has disulfide isomerase and transglutaminase-like cross-linking activity and is involved in the maintenance of body morphology. Journal of Biological Chemistry, 278, pp. 4227-4237. (doi:10.1074/jbc.M210510200)

Page, A. and Winter, A. (2003) Enzymes involved in the biogenesis of the nematode cuticle. Advances in Parasitology, 53, pp. 85-148.

Thein, M., McCormack, G., Winter, A., Johnstone, I., Shoemaker, C. and Page, A. (2003) Caenorhabditis elegans exoskeleton collagen COL-19: An adult-specific marker for collagen modification and assembly, and the analysis of organismal morphology. Developmental Dynamics, 226, pp. 523-539. (doi:10.1002/dvdy.10259)

Winter, A., Myllyharju, J. and Page, A. (2003) A hypodermally expressed prolyl 4-hydroxylase from the filarial nematode Brugia malayi is soluble and active in the absence of protein disulfide isomerase. Journal of Biological Chemistry, 278, pp. 2554-2562. (doi:10.1074/jbc.M210381200)

2002

Myllyharju, J., Kukkola, L., Winter, A. and Page, A. (2002) The exoskeleton collagens in Caenorhabditis elegans are modified by prolyl 4-hydroxylases with unique combinations of subunits. Journal of Biological Chemistry, 277, pp. 29187-29196. (doi:10.1074/jbc.M203824200)

Picken, N., Eschenlauer, S., Taylor, P., Page, A. and Walkinshaw, M. (2002) Structural and biological characterisation of the gut-associated cyclophilin B isoforms from Caenorhabditis elegans. Journal of Molecular Biology, 322, pp. 15-25. (doi:10.1016/S0022-2836(02)00712-X)

Riihimaa, P., Nissi, R., Page, A. , Winter, A., Keskiaho, K., Kivirikko, K. and Myllyharju, J. (2002) Egg shell collagen formation in Caenorhabditis elegans involves a novel prolyl 4-hydroxylase expressed in spermatheca and embryos and possessing many unique properties. Journal of Biological Chemistry, 277, pp. 18238-18243. (doi:10.1074/jbc.M200895200)

This list was generated on Fri Jul 19 05:14:24 2019 BST.
Number of items: 39.

Articles

Page, A. P. , Roberts, M., Felix, M.-A., Pickard, D., Page, A. and Weir, W. (2019) The golden death bacillus Chryseobacterium nematophagum is a novel matrix digesting pathogen of nematodes. BMC Biology, 17, 10. (doi:10.1186/s12915-019-0632-x) (PMID:30813925) (PMCID:PMC6394051)

Robertson, E., Harcus, Y., Johnston, C. J.C., Page, A. P. , Walkinshaw, M. D., Maizels, R. M. and Houston, D. (2018) Demonstration of the anthelmintic potency of marimastat in the Heligmosomoides polygyrus rodent model. Journal of Parasitology, 104(6), pp. 705-709. (doi:10.1645/18-33) (PMID:30085900)

Page, A. P. (2018) The sensory amphidial structures of Caenorhabditis elegans are involved in macrocyclic lactone uptake and anthelmintic resistance. International Journal for Parasitology, 48(13), pp. 1035-1042. (doi:10.1016/j.ijpara.2018.06.003) (PMID:30253131) (PMCID:PMC6237615)

France, D. J. , Stepek, G., Houston, D. R., Williams, L., McCormack, G., Walkinshaw, M. D. and Page, A. P. (2015) Identification and activity of inhibitors of the essential nematode-specific metalloprotease DPY-31. Bioorganic and Medicinal Chemistry Letters, (doi:10.1016/j.bmcl.2015.10.077) (PMID:26546217)

Stepek, G., McCormack, G., Winter, A. D. and Page, A. P. (2015) A highly conserved, inhibitable astacin metalloprotease from Teladorsagia circumcincta is required for cuticle formation and nematode development. International Journal for Parasitology, 45(3), pp. 345-355. (doi:10.1016/j.ijpara.2015.01.004) (PMID:25736599) (PMCID:PMC4406453)

Page, A. P. , Stepek, G., Winter, A. D. and Pertab, D. (2014) Enzymology of the nematode cuticle: a potential drug target? International Journal for Parasitology: Drugs and Drug Resistance, 4(2), pp. 133-141. (doi:10.1016/j.ijpddr.2014.05.003) (PMID:25057463) (PMCID:PMC4095051)

Winter, A., McCormack, G., Myllyharju, J. and Page, A. (2013) Prolyl 4-hydroxlase activity is essential for development and cuticle formation in the human infective parasitic nematode Brugia malayi. Journal of Biological Chemistry, 288(3), pp. 1750-1761. (doi:10.1074/jbc.M112.397604)

Dunsmore, C.J., Malone, K.J., Bailey, K.R., Wear, M.A., Florance, H., Shirran, S., Barran, P.E., Page, A.P. , Walkinshaw, M.D. and Turner, N.J. (2011) Design and Synthesis of Conformationally Constrained Cyclophilin Inhibitors Showing a Cyclosporin-A Phenotype in C. elegans. ChemBioChem, 12(5), pp. 802-810. (doi:10.1002/cbic.201000413)

Stepek, G., McCormack, G., Birnie, A.J. and Page, A.P. (2011) The astacin metalloprotease moulting enzyme NAS-36 is required for normal cuticle ecdysis in free-living and parasitic nematodes. Parasitology, 138(2), pp. 237-248. (doi:10.1017/S0031182010001113)

Stepek, G., McCormack, G. and Page, A. P. (2010) Collagen processing and cuticle formation is catalysed by the astacin metalloprotease DPY-31 in free-living and parasitic nematodes. International Journal for Parasitology, 40(5), pp. 533-542. (doi:10.1016/j.ijpara.2009.10.007)

Stepek, G., McCormack, G. and Page, A. P. (2010) The kunitz domain protein BLI-5 plays a functionally conserved role in cuticle formation in a diverse range of nematodes. Molecular and Biochemical Parasitology, 169(1), pp. 1-11. (doi:10.1016/j.molbiopara.2009.08.005)

Husi, H. et al. (2010) Selective Chemical Intervention in the Proteome ofCaenorhabditis elegans. Journal of Proteome Research, 9(11), pp. 6060-6070. (doi:10.1021/pr100427c)

Thein, M. C., Winter, A. D., Stepek, G., McCormack, G., Stapleton, G., Johnstone, I. L. and Page, A. P. (2009) Combined extracellular matrix cross-linking activity of the peroxidase MLT-7 and the dual oxidase BLI-3 is critical for post-embryonic viability in Caenorhabditis elegans. Journal of Biological Chemistry, 284(26), pp. 17549-17563. (doi:10.1074/jbc.M900831200)

Callister, D. M., Winter, A. D., Page, A. P. and Maizels, R. M. (2008) Four abundant novel transcript genes from Toxocara canis with unrelated coding sequences share untranslated region tracts implicated in the control of gene expression. Molecular and Biochemical Parasitology, 162(1), pp. 60-70. (doi:10.1016/j.molbiopara.2008.07.004)

Keskiaho, K., Kukkola, L., Page, A. P. , Winter, A. D., Vuoristo, J., Sormunen, R., Nissi, R., Riihimaa, P. and Myllyharju, J. (2008) Characterization of a novel Caenorhabditis elegans prolyl 4-hydroxylase with a unique substrate specificity and restricted expression in the pharynx and excretory duct. Journal of Biological Chemistry, 283(16), pp. 10679-10689. (doi:10.1074/jbc.M800972200)

Worrall, L. J., Wear, M. A., Page, A. P. and Walkinshaw, M. D. (2008) Cloning, purification and characterization of the Caenorhabditis elegans small glutamine-rich tetratricopeptide repeat-containing protein. Biochimica et Biophysica Acta: Proteins and Proteomics, 1784(3), pp. 496-503. (doi:10.1016/j.bbapap.2007.12.003) (PMID:18187053)

Yang, Y., Moir, E., Kontopidis, G., Taylor, P., Wear, M. A., Malone, K., Dunsmore, C. J., Page, A. P., Turner, N. J. and Walkinshaw, M. D. (2007) Structure-based discovery of a family of synthetic cyclophilin inhibitors showing a cyclosporin-A phenotype in Caenorhabditis elegans. Biochemical and Biophysical Research Communications, 363(4), pp. 1013-1019. (doi:10.1016/j.bbrc.2007.09.079)

Winter, A. D., McCormack, G. and Page, A. P. (2007) Protein disulfide isomerase activity is essential for viability and extracellular matrix formation in the nematode Caenorhabditis elegans. Developmental Biology, 308(2), pp. 449-461. (doi:10.1016/j.ydbio.2007.05.041)

Winter, A. D., Keskiaho, K., Kukkalo, L., McCormack, G., Felix, M.-A., Myllyharju, J. and Page, A. P. (2007) Differences in collagen prolyl 4-hydroxylase assembly between two Caenorhabditis nematode species despite high amino acid sequence identity of the enzyme subunits. Matrix Biology, 26(5), pp. 382-395. (doi:10.1016/j.matbio.2007.01.008)

Winter, A. D., Eschenlauer, S. C. P., McCormack, G. and Page, A. P. (2007) Loss of secretory pathway FK506-binding proteins results in cold-sensitive lethality in caenorhabditis elegans. Journal of Biological Chemistry, 282(17), pp. 12813-12821. (doi:10.1074/jbc.M700274200)

Richardson, J., Dornan, J., Opamawutthikul, M., Bruce, S., Page, A. and Walkinshaw, M. (2007) Cloning, expression and characterisation of FKB-6, the sole large TPR-containing immunophilin from C-elegans. Biochemical and Biophysical Research Communications, 360, pp. 566-572. (doi:10.1016/j.bbrc.2007.06.080)

Winter, A., Eschenlauer, S., McCormack, G. and Page, A. (2007) Loss of secretory pathway FK506-binding proteins results in cold-sensitive lethality and associate extracellular matrix defects in the nematode Caenorhabditis elegans. Journal of Biological Chemistry, 282, pp. 12813-12821. (doi:10.1074/jbc.M700274200)

Winter, A., McCormack, G. and Page, A. (2007) Protein disulfide isomerase activity is essential for viability and extracellular matrix formation in the nematode Caenorhabditis elegans. Developmental Biology, 308, pp. 449-461. (doi:10.1016/j.ydbio.2007.05.041)

Bell, A., Monaghan, P. and Page, A. (2006) Peptidyl-prolyl cis-trans isomerases (immunophilins) and their roles in parasite biochemistry, host-parasite interaction and antiparasitic drug action. International Journal for Parasitology, 36(3), pp. 261-276. (doi:10.1016/j.ijpara.2005.11.003)

Bell, A., Monaghan, P. and Page, A.P. (2006) Peptidyl-prolyl cis-trans isomerases (immunophilins) and their roles in parasite biochemistry, host-parasite interaction and antiparasitic drug action. International Journal for Parasitology, 36(3), pp. 261-276. (doi:10.1016/j.ijpara.2005.11.003)

Novelli, J., Page, A. and Hodgkin, J. (2006) The C terminus of collagen SQT-3 has complex and essential functions in nematode collagen assembly. Genetics, 172, pp. 2253-2267. (doi:10.1534/genetics.105.053637)

Page, A. P. , McCormack, G. and Birnie, A. J. (2006) Biosynthesis and enzymology of the Caenorhabditis elegans cuticle: identification and characterization of a novel serine protease inhibitor. International Journal for Parasitology, 36(6), pp. 681-689. (doi:10.1016/j.ijpara.2006.01.004)

Davis, M.W., Birnie, A.J., Chan, A.C., Page, A.P. and Jorgensen, A.M. (2004) A conserved metalloprotease mediates ecdysis in Caenorhabditis elegans. Development, 131, pp. 6001-6008. (doi:10.1242/dev.01454)

Davis, M., Birnie, A., Chan, A., Page, A. and Jorgensen, E. (2004) A conserved metalloprotease mediates ecdysis in Caenorhabditis elegans. Development, 131, pp. 6001-6008. (doi:10.1242/dev.01454)

Kukkola, L., Koivunen, P., Pakkanen, O., Page, A. and Myllyharju, J. (2004) Collagen prolyl 4-hydroxylase tetramers and dimers show identical decreases in K-m values for peptide substrates with increasing chain length - Mutation of one of the two catalytic sites in the tetramer inactivates the enzyme by more than half. Journal of Biological Chemistry, 279, pp. 18656-18661. (doi:10.1074/jbc.M401514200)

Eschenlauer, S. and Page, A. (2003) The Caenorhabditis elegans ERp60 homolog protein disulfide isomerase-3 has disulfide isomerase and transglutaminase-like cross-linking activity and is involved in the maintenance of body morphology. Journal of Biological Chemistry, 278, pp. 4227-4237. (doi:10.1074/jbc.M210510200)

Page, A. and Winter, A. (2003) Enzymes involved in the biogenesis of the nematode cuticle. Advances in Parasitology, 53, pp. 85-148.

Thein, M., McCormack, G., Winter, A., Johnstone, I., Shoemaker, C. and Page, A. (2003) Caenorhabditis elegans exoskeleton collagen COL-19: An adult-specific marker for collagen modification and assembly, and the analysis of organismal morphology. Developmental Dynamics, 226, pp. 523-539. (doi:10.1002/dvdy.10259)

Winter, A., Myllyharju, J. and Page, A. (2003) A hypodermally expressed prolyl 4-hydroxylase from the filarial nematode Brugia malayi is soluble and active in the absence of protein disulfide isomerase. Journal of Biological Chemistry, 278, pp. 2554-2562. (doi:10.1074/jbc.M210381200)

Myllyharju, J., Kukkola, L., Winter, A. and Page, A. (2002) The exoskeleton collagens in Caenorhabditis elegans are modified by prolyl 4-hydroxylases with unique combinations of subunits. Journal of Biological Chemistry, 277, pp. 29187-29196. (doi:10.1074/jbc.M203824200)

Picken, N., Eschenlauer, S., Taylor, P., Page, A. and Walkinshaw, M. (2002) Structural and biological characterisation of the gut-associated cyclophilin B isoforms from Caenorhabditis elegans. Journal of Molecular Biology, 322, pp. 15-25. (doi:10.1016/S0022-2836(02)00712-X)

Riihimaa, P., Nissi, R., Page, A. , Winter, A., Keskiaho, K., Kivirikko, K. and Myllyharju, J. (2002) Egg shell collagen formation in Caenorhabditis elegans involves a novel prolyl 4-hydroxylase expressed in spermatheca and embryos and possessing many unique properties. Journal of Biological Chemistry, 277, pp. 18238-18243. (doi:10.1074/jbc.M200895200)

Book Sections

Page, A.P. (2013) The nematode cuticle: synthesis, modification and turnover. In: Kennedy, M.W. and Harnett, W. (eds.) Parasitic Nematodes: Molecular Biology, Biochemistry and Immunology. Cabi Publishing, pp. 337-350. ISBN 9781845937591 (doi:10.1079/9781845937591.0337)

Page, A. P. and Johnstone, I. J. (2007) The cuticle. In: Kramer, J. M. and Moerman, D. G. (eds.) Wormbook. The C. elegans Research Community: http://www.wormbook.org.

This list was generated on Fri Jul 19 05:14:24 2019 BST.