Hantaan & Puumala viruses
Hantaan (HTNV) and Puumala (PUUV) viruses are members of the Hantavirus genus of emerging and reemerging zoonotic viruses in the family Bunyaviridae. Hantaviruses are maintained as persistent infections in rodents, insectivores, and bats. Some hantaviruses, such as Hantaan (HTNV) and Puumala (PUUV) viruses, can infect humans. HTNV causes haemorrhagic fever with renal syndrome (HFRS) in the Far East with a mortality rate up to 10%, while PUUV causes a milder form of HFRS, termed nephropathia epidemica, in Western Europe with a mortality rate of less than 1%.
Research in the CVR focuses on developing systems to study the interactions of these viruses with the innate immune response.