Research

Henderson, L. A., Mitchell, T., Steele, C. W., Roxburgh, C. S. D., Knight, K. A. (2026) A systematic review and meta-analysis of blood-based biomarkers in anal squamous cell cancer treated with chemoradiotherapy. Critical Reviews in Oncology/Hematology, 221, (doi: 10.1016/j.critrevonc.2026.105215)

Pea, A., He, X., Upstill-Goddard, R., Luchini, C., Schubert Santana, L. P., Dreyer, S., Duthie, F., Jamieson, N. B., McKay, C. J., Dickson, E. J., Pulvirenti, A., Rebus, S., Genomics Innovation Alliance, ., Scottish Genome Partnership, ., Piccoli, P., Sperandio, N., Lawlor, R. T., Milella, M., Froeling, F. E.M., Salvia, R., Scarpa, A., Bainkin, A. V., Wedge, D. C., Chang, D. K. (2026) Clonal evolutionary analysis reveals patterns of malignant transformation of Intraductal Papillary Mucinous Neoplasms of the pancreas. Nature Communications, (doi: 10.1038/s41467-026-69762-w)

Williams, H. L., Poulain, N., Powley, I., Martinelli, S., Bielik, R., Leslie, H., Nixon, C., Wilson, C. R., Sereno, M., He, Z., Offier-Jones, L., Ballantyne, F., Pennie, R., Wood, C. S., Lewis, D. Y., Jamieson, N. B., Le Quesne, J. (2026) Spatial molecular plasticity underpins lethal morphologies in lung adenocarcinoma. Modern Pathology, 39, (doi: 10.1016/j.modpat.2026.100960)

Himonas, E., de Beauchamp, L., Zerbst, D., Desmares-Romain, E., Sarnello, D., Kalkman, E., Rattigan, K., James, D., Shokry, E., Copland, M., Griessinger, E., Récher, C., de Mas, V., Vergez, F., Sumpton, D., Schimmer, A., Minden, M., Gottlieb, E., Shanks, E., Sarry, J.-E., Helgason, V. (2026) A metabolism-specific drug-repurposing screen reveals itraconazole as a potent OXPHOS inhibitor in acute myeloid leukemia. Blood, (doi: 10.1182/blood.2024027853)

White, M. et al. (2026) MAPK-driven epithelial cell plasticity drives colorectal cancer therapeutic resistance. Nature, 650, pp. 748-758. (doi: 10.1038/s41586-025-09916-w)

Vallatos, A., Al-Mubarak, H. F. I., Birch, J. L., Icer, Y., McBain, C., Coope, D. J., Karabatsou, K., Mills, S. J., Parker, G. J. M., Holmes, W. M., Chalmers, A. J., Jackson, A., Waldman, A., Thompson, G. (2026) Marginal diffusion slope as a prognostic imaging biomarker of infiltrating phenotype in glioblastoma; a cancer imaging biomarker roadmap study. Neuro-Oncology Advances, (doi: 10.1093/noajnl/vdag028)

Bryce, A. S., Martinelli, S., Schubert Santana, L., Officer-Jones, L., Baird, R. L., Ballantyne, F., Rakovic, K., Powley, I. R., Tataran, D., Meltzer, D. J., Walsh, C., Duthie, F., Farndale, L., Claudio Quiros, A., Yuan, K., Le Quesne, J., Froeling, F. E.M., Dreyer, S. B., Chang, D. K. (2026) Morphospatial profiling of cancer-associated fibroblasts reveals architectural subtypes of pancreatic ductal adenocarcinoma. bioRxiv, (doi: 10.64898/2026.02.06.704414)

Hillson, L. V.S. et al. (2026) Differential immunologic effects of short-course and long-course radiotherapy in locally advanced rectal cancer. Clinical Cancer Research, (doi: 10.1158/1078-0432.CCR-25-2733)

Patterson, S.D., Gottschalk, A., Hayden, C., Young, R., Hair, A., Jørgensen, H.G., Wheadon, H.W., Apperley, J.F., Glauche, I., Clark, R.E., Copland, M., Roeder, I. (2026) Sequential BCR::ABL1 evaluation during dose de-escalation in peripheral blood is more predictive of TFR success than single assessment at dose de-escalation in either peripheral blood or bone marrow. Leukemia, 40, pp. 459-463. (doi: 10.1038/s41375-025-02853-7)

Centeno, P. P., Chester, C., Kanellos, G., Ford, C. A., Cammarezi, P., Inman, G. J., Jamieson, T., Ridgeway, R. A., Marais, R., Campbell, A. D., Sansom, O. J. (2026) SOX2 confers tumour permissiveness in a specific skin progenitor population. Nature Communications, 17, (doi: 10.1038/s41467-025-66251-4)

Ren, H., Elliott, N., Lye, B., Sharif Shohan, M. U., Cross, J. W., Field, L., Ponnusamy, K., Rice, S., Jackson, T., Ilia, L., El Ouazzani, N., Thomas, R., Inglott, S., Bartram, J., Smith, O., Bond, J., Roberts, I. A. G., Halsey, C., Bashford-Rogers, R., Milne, T. A., Roy, A., Karadimitris, A. (2026) 'Off-the-shelf' dual CAR-iNKT cell immunotherapy eradicates medullary and leptomeningeal KMT2A-rearranged leukemia. Blood, 147, pp. 180-196. (doi: 10.1182/blood.2025029302)

Keeshan, K. (2026) Fetal defense against leukemia: a developmental shield. Blood, 147, pp. 7-8. (doi: 10.1182/blood.2025031544)

Tham, A., McMillan, D. C., Talwar, D., McSorley, S. T. (2026) Adjusting iron markers for inflammation reduces misclassification of iron deficiency after total hip arthroplasty. Journal of Clinical Medicine, 15, (doi: 10.3390/jcm15010259)

Banales, J. M. et al. (2026) Cholangiocarcinoma 2026: status quo, unmet needs and priorities. Nature Reviews Gastroenterology and Hepatology, 23, pp. 65-96. (doi: 10.1038/s41575-025-01153-w)

Smith, C. D.L., McMahon, A. D., Inman, G. J., Conway, D. I., Douglas, C. M., Paterson, C. (2026) The COVID-19 pandemic has not influenced survival outcomes of head and neck cancer squamous cell carcinomas in the West of Scotland: a retrospective cohort study. BJC Reports, 4, (doi: 10.1038/s44276-026-00203-3)

Kanellos, G. et al. (2025) Nucleophosmin supports WNT-driven hyperproliferation and tumour initiation. Nature Genetics, (doi: 10.1038/s41588-025-02408-7)

Kong, C. Y., Galbraith, N. J., McCormick, A., Haddock, A., Ratcliffe, M., Telfer, J., Lo, S., Fairbairn, N., Palmer, M., Teahan, S., Morton, S., Lindsay, R., Burton, K., Siddiqui, N., Roxburgh, C., Chong, P. S., Steele, C. W., Quinn, M. (2025) Resecting beyond the central pelvic compartment in pelvic exenterations for gynaecological malignancies: outcomes from a tertiary unit. Australian and New Zealand Journal of Obstetrics and Gynaecology, (doi: 10.1111/ajo.70079)

Gajic, N., Christie, R., Martin, J., Josephs-Spaulding, J., Lam, S., Ackermann, T., Dunn, K., Shokry, E., Huerta Uribe, A., Irving, J., van Delft, F., de Muyer, F., Ntziachristos, P., Vande Voorde, J., Sumpton, D., Tardito, S., Brown, A., Tait, S., Halsey, C. (2025) NADPH Controls a Cell State Vulnerability Towards Ferroptosis in Acute Lymphoblastic Leukaemia. (doi: 10.1182/blood-2025-144)

Gajic, N., Christie, R., Lam, S., Ackermann, T., Himonas, E., Josephs-Spaulding, J., Manoharan, A., Assmann, V., Martin, J., Collings, A., Dunn, K., Shokry, E., Huerta Uribe, A., Burns, S., O'Connor, D., Mansour, M., Sumpton, D., Helgason, G. V., Vande Voorde, J., Tardito, S., Tait, S., Halsey, C. (2025) Selenocysteine Dependency Renders Central Nervous System Leukaemia Therapeutically Sensitive to Ferroptosi. (doi: 10.1182/blood-2025-1526)

Duguid, A., Malouf, C., Nitsche, L., Halsey, C., Ottersbach, K. (2025) Mixed-lineage leukaemia cells undergo unique adaptations in the CNS niche. Experimental Hematology, (doi: 10.1016/j.exphem.2025.105347)

Mikkelsen, T., Helenius, M., Ampatzidou, M., Attarbaschi, A., Andres-Jensen, L., Borkhardt, A., Cuevas, N., Escherich, G., Hagleitner, M., Halsey, C., Josephs-Spaulding, J., Lundgren, L., Pehn, S., Polychronopoulou, S., Stoltze, U., Toksvang, L., Wahlberg, A., Junk, S., Schmiegelow, K. (2025) Role of common host genome variants in Childhood Acute Lymphoblastic Leukemia. Leukemia, (doi: 10.1038/s41375-025-02804-2)

Cong, B., Stamou, E., Pennel, K., Thakur, T., McKenzie, M., Matly, A., Gilroy, K., Shah, H., Gopinath, S., Edwards, J., Cagan, R. (2025) WNT signalling promotes NF-κB activation and drug resistance in KRAS-mutant colorectal cancer. EMBO Reports, 26, pp. 5728-5755. (doi: 10.1038/s44319-025-00588-1)

Lourenço, F. C., Sadien, I. D., Wong, K., Adler, S., Sawle, A., Schubert Santana, L., Hazelwood, L., Giavara, G., Nicholson, A. M., Eldridge, M. D., Maka, N., Lynch, G., McSorley, S. T., Edwards, J., Kemp, R., Adams, D. J., Winton, D. J. (2025) Decay of driver mutations shapes the landscape of intestinal transformation. Nature, (doi: 10.1038/s41586-025-09762-w)

Baird, R. L., Mason, D., Rakovic, K., Ballantyne, F., Powley, I. R., Georgakopoulou, A., Hillary, L., Bird, T. G., Officer-Jones, L., Le Quesne, J. (2025) PixlMap: a generalisable pixel classifier for cellular phenotyping in multiplex immunofluorescence images. PLoS ONE, 20, (doi: 10.1371/journal.pone.0317865)

Ponce-Garcia, F. M., Jenkins, Y. R., Assmann, V. D., Paul, S., Sharma, N. D., Moore, C., Ma, E. H., Diamanti, P., Hennequart, M., Blagih, J., Le, L., Jenkins, B. J., Rouvray, S., Cronin, J. G., Jones, R. G., Mansour, M., Blair, A., Halsey, C., Matlawska-Wasowska, K., Herranz, D., Vincent, E. E., Jones, N. (2025) Canagliflozin synergises with serine restriction mediating anti-leukaemic effects in T-cell acute lymphoblastic leukaemia. Molecular Metabolism, 102, (doi: 10.1016/j.molmet.2025.102275)

Rimini, M. et al. (2025) Durvalumab in advanced biliary tract cancer: real-world data from a large cohort of patients across multiple international centers. Liver International, 45, (doi: 10.1111/liv.70428)

Harryvan, T. J., Abudukelimu, S., Stouten, I., van der Wel, E. J., Janson, S. G.T., Lenos, K. J., Lannagan, T. R.M., White, M., Sansom, O. J., Verdegaal, E. M.E., Hawinkels, L. J.A.C. (2025) TGFβ signaling in cancer-associated fibroblasts drives a hepatic gp130-dependent pro-metastatic inflammatory program in colorectal cancer. iScience, 28, (doi: 10.1016/j.isci.2025.113696)

Raven, A. et al. (2025) Hepatic zonation determines tumorigenic potential of mutant β-catenin. Nature, (doi: 10.1038/s41586-025-09733-1)

Roche, J. J., Seyedshahi, F., Rakovic, K., Thu, A. W., Le Quesne, J., Blyth, K. G. (2025) Current and future applications of artificial intelligence in lung cancer and mesothelioma. Thorax, 80, pp. 957-965. (doi: 10.1136/thorax-2024-222054)

Young, J., Edwards, J., Park, J. H. (2025) The epidemiology, current evidence and controversies in diagnosis and management of patients with colorectal peritoneal metastases. Surgeon, (doi: 10.1016/j.surge.2025.11.001)

Knox, J. J. et al. (2025) PASS-01: Randomized Phase II Trial of Modified FOLFIRINOX Versus Gemcitabine/Nab-Paclitaxel and Molecular Correlatives for Previously Untreated Metastatic Pancreatic Cancer. Journal of Clinical Oncology, 43, pp. 3355-3368. (doi: 10.1200/JCO-25-00436)

Olaizola, I. et al. (2025) New platinum derivatives selectively cause double-strand DNA breaks and death in naïve and cisplatin-resistant cholangiocarcinomas. Journal of Hepatology, 83, pp. 1077-1091. (doi: 10.1016/j.jhep.2025.04.034)

Duncan, S., Kidd, A. C., Perdomo Lampignano, J., Cannon, P., Hall, M., Stobo, D. B., Maclay, J. D., Blyth, K. G., Lowe, D. J. (2025) Reference standard methodology in the clinical evaluation of AI chest X-ray algorithms for lung cancer detection: A systematic review. European Journal of Radiology, 192, (doi: 10.1016/j.ejrad.2025.112409)

Amaral, P., Christie, R., Gresham, D. O.F., Lucas, E. J.M., Xu, L. K., Behrmann, L., Bond, J., Degerman, S., van Delft, F. W., Goossens, S., Hagleitner, M., Halsey, C., Jones, N., Lammens, T., van Leeuwen, F. N., Mansour, M. R., Ntziachristos, P., O’Connor, D., Barata, J. T. (2025) Underlying biology, challenges and emergent concepts in the treatment of relapsed and refractory pediatric T-cell acute lymphoblastic leukemia. Leukemia, 39, pp. 2575-2589. (doi: 10.1038/s41375-025-02723-2)

Sharma, N. D., Keewan, E.’a., Ornatowski, W., Paul, S., Nysus, M., Barnett, C. C., Wolfson, J., Jacquez, Q., Myers, B. L., Kang, H., Zychowski, K. E., Winter, S. S., Loh, M. L., Hunger, S. P., Castillo, E. F., Taghon, T., Halsey, C., Vue, T. Y., Jones, N., Ntziachristos, P., Ksenia, M.-W. (2025) T-cell acute lymphoblastic leukemia exploits a neural proinflammatory pathway to colonize the meninges. Journal of Clinical Investigation, (doi: 10.1172/JCI188888)

Crellen, T., Vita, F., Braconi, C., Sithithaworn, P., Hollingsworth, T. D. (2025) Natural history of liver fluke infection underpins epidemiological patterns of biliary cancer. Proceedings of the National Academy of Sciences of the United States of America, 122, (doi: 10.1073/pnas.2423536122)

Bone, M., Inman, G. J. (2025) Alternative transcription increases isoform complexity in Long Non-Coding RNAs and alters their functions in cancer. Non-coding RNA Research, 14, pp. 38-50. (doi: 10.1016/j.ncrna.2025.04.008)

Salvador-Barbero, B., Alatsatianos, M., Morton, J. P., Sansom, O. J., Hogan, C. (2025) KRASG12D cells override homeostatic cell elimination mechanisms in adult pancreas via Wnt5a and cell dormancy. Gastroenterology, 169, pp. 983-999.e21. (doi: 10.1053/j.gastro.2025.02.042)

Rimini, M. et al. (2025) The impact of molecular alterations in patients with advanced biliary tract cancer receiving cisplatin, gemcitabine and durvalumab: a large real-life worldwide population. Journal of the National Cancer Institute, 117, pp. 2029-2043. (doi: 10.1093/jnci/djaf155)

Mallu, A. C. T., Coffelt, S. B. (2025) γδT cells and breast cancer: wicked allies. Trends in Cancer, 11, pp. 920-922. (doi: 10.1016/j.trecan.2025.08.015)

Cong, B., Thakur, T., Huerta Uribe, A., Stamou, E., Gopinath, S., Sansom, O., Maddocks, O., Cagan, R. (2025) Colon cancer cells evade drug action by enhancing drug metabolism. Oncogene, 44, pp. 3284-3296. (doi: 10.1038/s41388-025-03472-3)

Tesini, G., Ibrahim, H., Rimassa, L., Braconi, C. (2025) Evolving precision: updates in targeted therapy for cholangiocarcinoma. Hepatology, (doi: 10.1097/HEP.0000000000001541)

Rimini, M. et al. (2025) Factors associated with reaching maintenance therapy in patients with advanced biliary tract cancer treated with durvalumab: real‐world results from a multicenter and multinational study. International Journal of Cancer, 157, pp. 1246-1259. (doi: 10.1002/ijc.35481)

Sofianidi, A. A., Syrigos, N. K., Blyth, K. G., Charpidou, A., Vathiotis, I. A. (2025) Breaking through: immunotherapy innovations in pleural mesothelioma. Clinical Lung Cancer, 26, pp. 458-469. (doi: 10.1016/j.cllc.2025.04.008)

Bone, M., Schreyer, D., Treanor-Taylor, M., Proby, C., Harwood, C., Leigh, I. M., Bailey, P., Inman, G. (2025) The landscape of long noncoding RNA during cutaneous squamous cell carcinoma progression. British Journal of Dermatology, 193, pp. 490-501. (doi: 10.1093/bjd/ljaf108)

Whyte, D. et al. (2025) Uridine phosphorylase-1 supports metastasis by altering immune and extracellular matrix landscapes. EMBO Reports, 26, pp. 4248-4282. (doi: 10.1038/s44319-025-00520-7)

Cammareri, P. et al. (2025) Loss of colonic fidelity enables multilineage plasticity and metastasis. Nature, 644, pp. 547-556. (doi: 10.1038/s41586-025-09125-5)

Tate, M. et al. (2025) Clinical effectiveness, safety and viral mutagenicity of oral favipiravir for COVID-19: results from a community-based, open-label, randomised, phase III trial. Antimicrobial Agents and Chemotherapy, 69, (doi: 10.1128/aac.00054-25)

Herbert, K. J., Upstill-Goddard, R., Dreyer, S. B., Rebus, S., Pilarsky, C., Debabrata, M., Lord, C. J., Biankin, A. V., Froeling, F. E.M., Chang, D. K. (2025) Sequential ATR and PARP inhibition overcomes acquired DNA damaging agent resistance in pancreatic ductal adenocarcinoma. British Journal of Cancer, 133, pp. 381-393. (doi: 10.1038/s41416-025-03051-z)

Pea, A. et al. (2025) Mucinous cystic neoplasms and simple mucinous cysts are two distinct precursors of pancreatic cancer: clinicopathological, genomic, and transcriptomic characterization. Journal of Pathology, 266, pp. 421-434. (doi: 10.1002/path.6437)

Prinzi, F. L. et al. (2025) Negative impact of corticosteroid use on outcome in patients with advanced BTCs treated with cisplatin, gemcitabine, and durvalumab: a large real‐life worldwide population. International Journal of Cancer, (doi: 10.1002/ijc.70009)

Bullock, E., Rozyczko, A., Shabbir, S., Tsoupi, I., Young, A. I. J., Travnickova, J., Gómez-Cuadrado, L., Mabruk, Z., Carrasco, G., Morrow, E., Pennel, K., Kloosterman, P., Houthuijzen, J. M., Jonkers, J., Avalle, L., Poli, V., Iggo, R., Xiao, X., Guo, J., Zhu, X., Mallon, E., Edwards, J., Patton, E., Brunton, V. G. (2025) Cancer-associated fibroblast driven paracrine IL-6/STAT3 signaling promotes migration and dissemination in invasive lobular carcinoma. Breast Cancer Research, 27, (doi: 10.1186/s13058-025-02074-x)

Persano, M. et al. (2025) A prognostic index for advanced biliary tract cancer treated with cisplatin, gemcitabine and durvalumab: the MAGIC-D index. Liver International, 45, (doi: 10.1111/liv.70181)

Wood, H., O'Nions, J., Chan, W. Y., Borg, A., Veitch, S., Elder, P., Jain, M., Aries, J., Leak, S., Mitchell, E., Pavlu, J., Othman, J., Dillon, R., Mehta, P., Murthy, V., Knapper, S., Potter, V., Copland, M., Craddock, C., Krishnamurthy, P. (2025) Venetoclax-based non-intensive combinations for relapsed/refractory acute myeloid leukaemia: Real-world data from a UK-wide programme. British Journal of Haematology, 207, pp. 254-259. (doi: 10.1111/bjh.20149)

Cheng, C. et al. (2025) Targeting PIKfyve-driven lipid metabolism in pancreatic cancer. Nature, 642, pp. 776-784. (doi: 10.1038/s41586-025-08917-z)

Pfister, M., Ratti, F., Gores, G. J., Lesurtel, M., Chiche, L., Ebata, T., Ardiles, V., Valle, J. W., Heimbach, J. K., Braconi, C., Bruix, J., Aldrighetti, L., Clavien, P.-A. (2025) Recommendations on Perihilar Cholangiocarcinoma. The Milan Jury-Based Consensus. Annals of Surgery, (doi: 10.1097/sla.0000000000006773)

Saeed, R., McSorley, S., Cascales, A., McMillan, D. (2025) The prognostic/ predictive value of the systematic inflammatory response in patients receiving immunotherapy for non-small cell lung cancer: a systematic review and meta-analysis. BMC Cancer, 25, (doi: 10.1186/s12885-025-13822-9)

Castet, F. et al. (2025) Association of candidate surrogate endpoints with overall survival in advanced biliary tract cancer. Journal of Hepatology, (doi: 10.1016/j.jhep.2025.05.020)

McMahon, R., O'Cathail, S., Steele, C., Nair, H., Platt, J. J., McMillan, D. C., Horgan, P. G., Roxburgh, C.S.D. (2025) Circulating markers of systemic inflammation, measured after completion of neoadjuvant therapy, associated with response in locally advanced rectal cancer. Diseases of the Colon and Rectum, 68, pp. 713-725. (doi: 10.1097/DCR.0000000000003660)

Dreyer, S. B., Beer, P., Hingorani, S. R., Biankin, A. (2025) Improving outcomes of patients with pancreatic cancer. Nature Reviews Clinical Oncology, 22, pp. 439-456. (doi: 10.1038/s41571-025-01019-9)

Hurley, R., Paterson, C., Conway, D. I., Inman, G. J., Douglas, C. M. (2025) Laryngeal cancer in the West of Scotland 2014–2020: trends and survival in a cohort of 867 patients. Laryngoscope, 135, pp. 2051-2061. (doi: 10.1002/lary.31992)

Rovers, S., Farahmand, P., Liu, D., Brants, L., Hermans, C., Peeters, D., McKinven, D., Doig, J., Lardon, F., van Meerbeeck, J., Marcq, E., Murphy, D. J., Smits, E. (2025) A minimally invasive transthoracic injection technique for reproducible intrapleural delivery in mice. Methods and Protocols, 8, (doi: 10.3390/mps8030055)

May, S., Stevenson, K., Alqarafi, B., Yin Swe, K. L., Bloom, A., Mackintosh, A., Müller, M., Georgakopoulou, A., Drake, T. M., Kiourtis, C., Karim, S. A., Nixon, C., Cadden, B., Duffton, A., Grose, D., Lewis, D. Y., Blyth, K., Chalmers, A. J., Bird, T. G. (2025) A precision image-guided model of stereotactic ablative radiotherapy for hepatocellular carcinoma. Disease Models and Mechanisms, 18, (doi: 10.1242/dmm.052301)

Biglin, E. R., Silvestre Patallo, I., Morris, A., Carter, R., Curley, E., Ghita, M., Hill, M. A., Lefebvre, T. L., Lewis, D., Nill, S., Schettino, G., Stevenson, K., Aitkenhead, A. H. (2025) A survey of dosimetry quality assurance practice at UK small animal radiation research platform (SARRP) facilities. Biomedical Physics and Engineering Express, 11, (doi: 10.1088/2057-1976/adcc35)

Woraharn, W., McCulloch, A., Bigley, C., Hatthakarnkul, P., Pennel, K., Alexander, P., Van Wyk, H., Roseweir, A., Hay, J., Maka, N., Park, J., Jamieson, N. B., Edwards, J., Roxburgh, C. S.D. (2025) Investigation of three alternative histopathological scoring methods at the invasive tumour front in colorectal cancer. Journal of Pathology: Clinical Research, 11, (doi: 10.1002/2056-4538.70031)

Dehghani, P., Salehirozveh, M., Tajabadi, A., Yeung, C. C., Lam, M., Leung, H. Y., Roy, V. A.L. (2025) Next-gen point-of-care tool for ultra-sensitive detection of urinary spermine for prostate cancer diagnosis. ACS Sensors, 10, pp. 2640-2651. (doi: 10.1021/acssensors.4c03250)

Hartley, A., Galbraith, L. C.A., Shaw, R., Tibbo, A., Veeratterapillay, R., Wilson, L., Heer, R., Blyth, K., Leung, H., Ahmad, I. (2025) Loss of ARID1A accelerates prostate tumourigenesis with a proliferative collagen-poor phenotype through co-operation with AP1 subunit cFos. British Journal of Cancer, 132, pp. 502-512. (doi: 10.1038/s41416-025-02944-3)

Woolley, C. E., Domingo, E., Fernandez-Tajes, J., Pennel, K., Roxburgh, P., Edwards, J., Richman, S. D., Maughan, T. S., Kerr, D. J., Soriano, I., Tomlinson, I. P.M. (2025) Coevolution of atypical BRAF and KRAS mutations in colorectal tumorigenesis. Molecular Cancer Research, 23, pp. 300-312. (doi: 10.1158/1541-7786.mcr-24-0464)

Hurley, R., Osbourne, J., Inman, G. J., Conway, D. I., Paterson, C., Douglas, C. (2025) Pre-treatment serum prognostic scores and survival in curatively treated laryngeal cancer. Laryngoscope Investigative Otolaryngology, 10, (doi: 10.1002/lio2.70124)

Mathews, C., Nauman, A., Johnstone, M., Stoops, R., Tham, A., Parsons, E. C., Robb, K. A., Sloan, W., Lynch, G., Edwards, J., McSorley, S. T. (2025) Retrospective cohort study: scope for improvement - barriers to post-polypectomy surveillance in the integrated technologies for improved polyp surveillance cohort. Alimentary Pharmacology and Therapeutics, 61, pp. 1381-1386. (doi: 10.1111/apt.18514)

Omar, R., Lee, M. A.W., Gonzalez-Trueba, L., Thomson, C. R., Hansen, U., Lianos, S., Hazarika, S., El Abdallah, O., Ammar, M. A., Cassels, J., Michie, A. M., Bulleid, N. J., Malfait, F., Van Agtmael, T. (2025) The chemical chaperone 4-phenylbutyric acid rescues molecular cell defects of COL3A1 mutations that cause vascular Ehlers Danlos Syndrome. Cell Death Discovery, 11, (doi: 10.1038/s41420-025-02476-y)

Zanuso, V., Rimassa, L., Braconi, C. (2025) The rapidly evolving landscape of HCC: Selecting the optimal systemic therapy. Hepatology, 81, pp. 1365-1386. (doi: 10.1097/HEP.0000000000000572)

Thompson, J. J., MacLeod, N., Will, S., O'Rourke, F., McGovern, J., Roxburgh, C., Edwards, J., Dolan, R. D., McMillan, D. C. (2025) The prognostic value of a laboratory cachexia score (LCAS) defined by LDH, CRP and albumin in patients with advanced lung cancer. BMC Cancer, 25, (doi: 10.1186/s12885-025-13426-3)

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Tarafdar, A., Hopcroft, L. E.M., Gallipolli, P., Pellicano, F., Cassels, J., Hair, A., Korfi, K., Jørgensen, H. G., Vetrie, D., Holyoake, T. L., Michie, A. M. (2017) CML cells actively evade host immune surveillance through cytokine-mediated downregulation of MHC-II expression. Blood, 129, pp. 199-208. (doi: 10.1182/blood-2016-09-742049)

van der Weyden, L., Arends, M. J., Campbell, A. D., Bald, T., Wardle-Jones, H., Griggs, N., Del Castillo Velasco-Herrera, M., Tüting, T., Sansom, O. J., Karp, N. A., Clare, S., Gleeson, D., Ryder, E., Galli, A., Tuck, E., Cambridge, E. L., Voet, T., Macaulay, I. C., Wong, K., Spiegel, S., Speak, A. O., Adams, D. J. (2017) Genome-wide in vivo screen identifies novel host regulators of metastatic colonization. Nature, 541, pp. 233-236. (doi: 10.1038/nature20792)

Sarosiek, K. A., Fraser, C., Muthalagu, N., Bhola, P. D., Chang, W., McBrayer, S. K., Cantlon, A., Fisch, S., Golomb-Mello, G., Ryan, J. A., Deng, J., Jian, B., Corbett, C., Goldenberg, M., Madsen, J. R., Liao, R., Walsh, D., Sedivy, J., Murphy, D. J., Carrasco, D. R., Robinson, S., Moslehi, J., Letai, A. (2017) Developmental regulation of mitochondrial apoptosis by c-Myc governs age- and tissue-specific sensitivity to cancer therapeutics. Cancer Cell, 31, pp. 142-156. (doi: 10.1016/j.ccell.2016.11.011)

Diaz-Vera, J., Palmer, S., Hernandez-Fernaud, J. R., Dornier, E., Mitchell, L. E., MacPherson, I., Edwards, J., Zanivan, S., Norman, J. C. (2017) A proteomic approach to identify endosomal cargoes controlling cancer invasiveness. Journal of Cell Science, 130, pp. 697-711. (doi: 10.1242/jcs.190835)

Iltzsche, F., Simon, K., Stopp, S., Pattschull, G., Francke, S., Wolter, P., Hauser, S., Murphy, D.J., Garcia, P., Rosenwald, A., Gaubatz, S. (2017) An important role for Myb-MuvB and its target gene KIF23 in a mouse model of lung adenocarcinoma. Oncogene, 36, pp. 110-121. (doi: 10.1038/onc.2016.181)

Jackstadt, R., Sansom, O. J. (2017) The Wae to repair: prostaglandin E2 (PGE2) triggers intestinal wound repair. EMBO Journal, 36, pp. 3-4. (doi: 10.15252/embj.201695973)

Oruganti, S.R., Torres, D.J., Krebsbach, S., Asperti-Boursin, F., Winters, J., Matlawska-Wasowska, K., Winter, S.S., Halsey, C., Cannon, J.L. (2017) CARMA1 is a novel regulator of T-ALL disease and leukemic cell migration to the CNS. Leukemia, 31, pp. 255-258. (doi: 10.1038/leu.2016.272)

Morton, J. P., Sansom, O. J. (2017) CXCR2 inhibition in pancreatic cancer: opportunities for immunotherapy? Immunotherapy, 9, pp. 9-12. (doi: 10.2217/imt-2016-0115)

Humphris, J. L. et al. (2017) Hypermutation in pancreatic cancer. Gastroenterology, 152, pp. 68-74.e2. (doi: 10.1053/j.gastro.2016.09.060)

Tsim, S., Stobo, D. B., Alexander, L., Kelly, C., Blyth, K. G. (2017) The diagnostic performance of routinely acquired and reported computed tomography imaging in patients presenting with suspected pleural malignancy. Lung Cancer, 103, pp. 38-43. (doi: 10.1016/j.lungcan.2016.11.010)

Khor, B. Y., McSorley, S. T., Horgan, P. G., McMillan, D. C. (2017) The relationship between systemic inflammation and stoma formation following anterior resection for rectal cancer: a cross-sectional study. International Journal of Surgery, 37, pp. 79-84. (doi: 10.1016/j.ijsu.2016.12.010)

Ritschka, B., Storer, M., Mas, A., Heinzmann, F., Ortells, M. C., Morton, J. P., Sansom, O. J., Zender, L., Keyes, W. M. (2017) The senescence-associated secretory phenotype induces cellular plasticity and tissue regeneration. Genes and Development, 31, pp. 172-183. (doi: 10.1101/gad.290635.116)

Horne, G. A., Copland, M. (2017) Approaches for targeting self-renewal pathways in cancer stem cells: implications for hematological treatments. Expert Opinion on Drug Discovery, 12, pp. 465-474. (doi: 10.1080/17460441.2017.1303477)

Dolan, R., McLeod, N., McSorley, S., McMillan, D., Horgan, P. (2017) Evaluation of Systemic Inflammation Based Prognostic Scoresin Patients with Advanced Rectal Cancer Receiving Palliative Pelvicradiotherapy.

McSorley, S. T., Dolan, R. D., Roxburgh, C. S.D., McMillan, D. C., Horgan, P. G. (2017) How and why systemic inflammation worsens quality of life in patients with advanced cancer. Expert Review of Quality of Life in Cancer Care, 2, pp. 167-175. (doi: 10.1080/23809000.2017.1331705)

Rose, A. M., Sansom, O. J., Inman, G. J. (2017) Loss of TGF-β signaling drives cSCC from skin stem cells – More evidence. Cell Cycle, 16, pp. 386-387. (doi: 10.1080/15384101.2016.1259892)

Kersten, K., Coffelt, S. B., Hoogstraat, M., Verstegen, N. J.M., Vrijland, K., Ciampricotti, M., Doornebal, C. W., Hau, C.-S., Wellenstein, M. D., Salvagno, C., Doshi, P., Lips, E. H., Wessels, L. F.A., de Visser, K. E. (2017) Mammary tumor-derived CCL2 enhances pro-metastatic systemic inflammation through upregulation of IL1β in tumor-associated macrophages. OncoImmunology, 6, (doi: 10.1080/2162402X.2017.1334744)

Carter, L., Rothwell, D. G., Mesquita, B., Smowton, C., Leong, H. S., Fernandez-Gutierrez, F., Li, Y., Burt, D. J., Antonello, J., Morrow, C. J., Hodgkinson, C. L., Morris, K., Priest, L., Carter, M., Miller, C., Hughes, A., Blackhall, F., Dive, C., Brady, G. (2017) Molecular analysis of circulating tumor cells identifies distinct copy-number profiles in patients with chemosensitive and chemorefractory small-cell lung cancer. Nature Medicine, 23, pp. 114-119. (doi: 10.1038/nm.4239)

Draper, J. E., Sroczynska, P., Leong, H. S., Fadlullah, M. Z. H., Miller, C., Kouskoff, V., Lacaud, G. (2017) Mouse RUNX1C regulates premegakaryocytic/erythroid output and maintains survival of megakaryocyte progenitors. Blood, 130, pp. 271-284. (doi: 10.1182/blood-2016-06-723635)

Dolan, R., McSorley, S., McMillan, D., Horgan, P. (2017) Ongoing Systemic Inflammatory Response at Diagnosis is Notassociated with Lower Lymph Node Retrieval and Higher Node Positivityin Patients Undergoing Surgery for Colonic Cancer.

Horne, G., Jackson, L., Helgason, V., Holyoake, T. L. (2017) Stem cell guardians – old and new perspectives in LSC biology. Current Drug Targets, 18, pp. 405-413. (doi: 10.2174/1389450117666160712092944)

Wildenberg, M.E., Koelink, P.J., Diederen, K., te Velde, A.A., Wolfkamp, S.C.S., Nuij, V.J., Peppelenbosch, M.P., Nobis, M., Sansom, O.J., Anderson, K.I., van der Woude, C.J., D’Haens, G.R.A.M., van den Brink, G.R. (2017) The ATG16L1 risk allele associated with Crohn’s disease results in a Rac1-dependent defect in dendritic cell migration that is corrected by thiopurines. Mucosal Immunology, 10, pp. 352-360. (doi: 10.1038/mi.2016.65)