The Glasgow Molecular Pathology Node was established in November 2015 with MRC/EPSRC funding and is located in the Laboratory Medicine Building within the new £1 billion Queen Elizabeth University Hospital (QEUH) campus. The Pathology Department provides comprehensive Histopathology and Cytopathology services, including Paediatric and Neuropathology and processes around 100,000 histopathology requests and 20,000 non-gynaecological cytopathology requests annually. Molecular diagnostics is located beside Pathology and offers a regional and Scottish national service, testing over 30,000 specimens annually. The Molecular Diagnostics Laboratory is accredited by Clinical Pathology Accreditation (CPA) UK and possesses hardware and software to deliver Next Generation Sequencing (NGS). Embedding the Node within this large high-quality clinical laboratory enables costs and cultures to be shared and development pipelines to be firmly rooted in clinical practice and widely translatable.