The course will focus on the molecular and cellular biology of the interaction between infectious agents (bacteria, parasites and viruses) and the cells and hosts they infect. Student-led sessions will investigate current key topics in molecular microbiology such as antimicrobial resistance, immune evasion by pathogens and "omics" approaches to studying infectious disease. Understanding the underlying molecular and cellular biology of such topics will allow students to extrapolate their knowledge to discover modern drug, therapy and diagnostics design for infectious diseases such as influenza and trypanosomiasis. This course aims to give students an appreciation of how our knowledge of biomolecular science can be used in the real world to combat infectious disease.

There are normally 3 hours of teaching on Fridays, which may be split over more than one session and three tutorials, normally on Monday mornings, to support the in-course assessment.

None

The course will be assessed by a 2-hour examination (67%) and in-course assessment consisting of a tutored, open book interpretation and data analysis of a provided scientific paper (33%).

The aims of the course are:

■ To provide students with a deep understanding of the molecular relationships between infectious agents and the cells and hosts they infect

■ To enable students to appreciate how understanding these relationships can underpin design of drugs and therapies against infectious disease.

By the end of this course students will be able to:

■ Critically discuss the molecular mechanisms by which a range of pathogens infect cells and hosts;

■ Describe how pathogens survive within and transmit between hosts;

■ Examine how host cell components are modified by infectious agents;

■ Appraise potential avenues for drug design against pathogens;

■ Analyse data from the current molecular microbiology literature.