This course is designed to offer students exposure to state-of-the-art knowledge in aspects of cellular biochemistry and cell biology as they relate to cell compartmentalisation.

There are normally 3 hours of teaching on Fridays.

None

The course will be assessed by a 2-hour examination (75%) and in-course assessment consisting of a prescribed review of a research paper (25%). 

This course aims to explore cellular compartmentalisation, with an emphasis on new advances in several key areas, notably around protein synthesis (e.g. the structure of the ribosome, protein insertion into the ER, etc), protein sorting, the integration of signalling and trafficking, the use of model organisms to probe complex cellular systems, and integrating material from 'omic' technologies. 

By the end of this course, students will be able to: 

■ With reference to examples introduced within the course, explain how different forms of cellular compartmentalisation are achieved and explain why compartmentalisation is important to the specific biochemical functions associated with different cellular compartments.

■ Appraise and interpret experimental results and data from relevant primary literature.

■ Critically evaluate the hypotheses tested and conclusions made within relevant primary literature and use this to enhance your understanding of the subject.