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Matthew.Gould@glasgow.ac.uk
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Rao, S. P. S. et al. (2023) Cyanotriazoles are selective topoisomerase II poisons that rapidly cure trypanosome infections. Science, 380(6652), pp. 1349-1356. (doi: 10.1126/science.adh0614) (PMID:37384702)
Dickie, E. A., Giordani, F. , Gould, M. K., Maeser, P., Burri, C., Mottram, J. C. , Rao, S. P.S. and Barrett, M. P. (2020) New drugs for human African trypanosomiasis:a twenty first century success story. Tropical Medicine and Infectious Disease, 5(1), 29. (doi: 10.3390/tropicalmed5010029) (PMID:32092897) (PMCID:PMC7157223)
Gould, M.K., Bachmaier, S., Ali, J.A.M., Alsford, S., Tagoe, D.N.A., Munday, J.C. , Schnaufer, A.C., Horn, D., Boshart, M. and De Koning, H. (2013) Cyclic AMP effectors in African trypanosomes revealed by genome-scale RNA interference library screening for resistance to the phosphodiesterase inhibitor CpdA. Antimicrobial Agents and Chemotherapy, 57(10), pp. 4882-4893. (doi: 10.1128/AAC.00508-13)
Gould, M.K. and De Koning, H.P. (2011) Cyclic-nucleotide signalling in protozoa. FEMS Microbiology Reviews, 31(3), pp. 515-541. (doi: 10.1111/j.1574-6976.2010.00262.x)
Rodenko, B., van der Burg, A. M., Wanner, M. J., Kaiser, M., Brun, R., Gould, M., de Koning, H. P. and Koomen, G.-J. (2007) 2,N6-disubstituted adenosine analogs with antitrypanosomal and antimalarial activities. Antimicrobial Agents and Chemotherapy, 51(11), pp. 3796-3802. (doi: 10.1128/AAC.00425-07) (PMID:17698622) (PMCID:PMC2151466)
Bridges, D. J., Gould, M. K., Nerima, B., Maser, P., Burchmore, R. J. S. and de Koning, H. P. (2007) Loss of the high-affinity pentamidine transporter is responsible for high levels of cross-resistance between arsenical and diamidine drugs in African trypanosomes. Molecular Pharmacology, 71, pp. 1098-1108. (doi: 10.1124/mol.106.031351)
Rao, S. P. S. et al. (2023) Cyanotriazoles are selective topoisomerase II poisons that rapidly cure trypanosome infections. Science, 380(6652), pp. 1349-1356. (doi: 10.1126/science.adh0614) (PMID:37384702)
Dickie, E. A., Giordani, F. , Gould, M. K., Maeser, P., Burri, C., Mottram, J. C. , Rao, S. P.S. and Barrett, M. P. (2020) New drugs for human African trypanosomiasis:a twenty first century success story. Tropical Medicine and Infectious Disease, 5(1), 29. (doi: 10.3390/tropicalmed5010029) (PMID:32092897) (PMCID:PMC7157223)
Gould, M.K., Bachmaier, S., Ali, J.A.M., Alsford, S., Tagoe, D.N.A., Munday, J.C. , Schnaufer, A.C., Horn, D., Boshart, M. and De Koning, H. (2013) Cyclic AMP effectors in African trypanosomes revealed by genome-scale RNA interference library screening for resistance to the phosphodiesterase inhibitor CpdA. Antimicrobial Agents and Chemotherapy, 57(10), pp. 4882-4893. (doi: 10.1128/AAC.00508-13)
Gould, M.K. and De Koning, H.P. (2011) Cyclic-nucleotide signalling in protozoa. FEMS Microbiology Reviews, 31(3), pp. 515-541. (doi: 10.1111/j.1574-6976.2010.00262.x)
Rodenko, B., van der Burg, A. M., Wanner, M. J., Kaiser, M., Brun, R., Gould, M., de Koning, H. P. and Koomen, G.-J. (2007) 2,N6-disubstituted adenosine analogs with antitrypanosomal and antimalarial activities. Antimicrobial Agents and Chemotherapy, 51(11), pp. 3796-3802. (doi: 10.1128/AAC.00425-07) (PMID:17698622) (PMCID:PMC2151466)
Bridges, D. J., Gould, M. K., Nerima, B., Maser, P., Burchmore, R. J. S. and de Koning, H. P. (2007) Loss of the high-affinity pentamidine transporter is responsible for high levels of cross-resistance between arsenical and diamidine drugs in African trypanosomes. Molecular Pharmacology, 71, pp. 1098-1108. (doi: 10.1124/mol.106.031351)