Mr Clement Regnault
- Biochemical Data Analyst (MVLS Research Facilities)
email:
Clement.Regnault@glasgow.ac.uk
Room B3.08, Joseph Black Building, University of Glasgow Gilmorehill Campus, University Place, Glasgow, G128QQ
Publications
2025
McCreath, Gordan, Regnault, Clément, Blackburn, Gavin J. ORCID: https://orcid.org/0000-0003-1037-6012, Daly, Rónán
ORCID: https://orcid.org/0000-0002-1275-6820, Leanord, Alistair T., Whitfield, Phillip D.
ORCID: https://orcid.org/0000-0002-0814-4119, Roe, Andrew J.
ORCID: https://orcid.org/0000-0003-3698-6134, Davidson, Alan, Watson, Malcolm J. and Sim, Malcolm A. B.
(2025)
Metabolomics for the diagnosis of secondary infections in critically ill patients with COVID-19.
Critical Care Explorations,
(Accepted for Publication)
Haines, L. R. et al. (2025) Anopheles mosquito survival and pharmacokinetic modeling show the mosquitocidal activity of nitisinone. Science Translational Medicine, 17(791), eadr4827. (doi: 10.1126/scitranslmed.adr4827) (PMID:40138457)
Ilbeigi, K. et al. (2025) Discovery and development of an advanced lead for the treatment of African trypanosomiasis. ACS Infectious Diseases, 11(1), pp. 131-143. (doi: 10.1021/acsinfecdis.4c00472) (PMID:39665421)
2023
Simwela, N. V. et al. (2023) A conserved metabolic signature associated with response to fast-acting anti-malarial agents. Microbiology Spectrum, 11(6), e0397622. (doi: 10.1128/spectrum.03976-22) (PMID:37800971) (PMCID:PMC10714989)
Crozier, L. et al. (2023) CDK4/6 inhibitor-mediated cell overgrowth triggers osmotic and replication stress to promote senescence. Molecular Cell, 83(22), 4062-4077.e5. (doi: 10.1016/j.molcel.2023.10.016) (PMID:37977118)
Năstase, A.-M. et al. (2023) Alignment of multiple metabolomics LC-MS datasets from disparate diseases to reveal fever-associated metabolites. PLoS Neglected Tropical Diseases, 17(7), e0011133. (doi: 10.1371/journal.pntd.0011133) (PMID:37486920) (PMCID:PMC10399774)
2022
O'Brien, Á. C. et al. (2022) Using organic contaminants to constrain the terrestrial journey of the martian meteorite Lafayette. Astrobiology, 22(11), pp. 1351-1362. (doi: 10.1089/ast.2021.0180) (PMID:36264546) (PMCID:PMC9618387)
Apostolopoulou, Natalia G., Smeti, Evangelia, Lamorgese, Marta, Varkitzi, Ioanna, Whitfield, Phillip, Regnault, Clement and Spatharis, Sofie ORCID: https://orcid.org/0000-0003-1030-9821
(2022)
Microalgae show a range of responses to exometabolites of foreign species.
Algal Research, 62,
102627.
(doi: 10.1016/j.algal.2021.102627)
(PMID:35311224)
(PMCID:PMC8924005)
Rubić, I. et al. (2022) Multi platforms strategies and metabolomics approaches for the investigation of comprehensive metabolite profile in dogs with Babesia canis infection. International Journal of Molecular Sciences, 23(3), 1575. (doi: 10.3390/ijms23031575) (PMID:35163517) (PMCID:PMC8835742)
Jara, Marlene, Barrett, Michael ORCID: https://orcid.org/0000-0001-9447-3519, Maes, Ilse, Regnault, Clement, Imamura, Hideo, Domagalska, Malgorzata Anna and Dujardin, Jean-Claude
(2022)
Transcriptional shift and metabolic adaptations during Leishmania quiescence using stationary phase and drug pressure as models.
Microorganisms, 10(1),
97.
(doi: 10.3390/microorganisms10010097)
(PMID:35056546)
(PMCID:PMC8781126)
2021
Milne, K. et al. (2021) Mapping immune variation and var gene switching in naive hosts infected with Plasmodium falciparum. eLife, 10, e62800. (doi: 10.7554/elife.62800) (PMID:33648633) (PMCID:PMC7924948)
2020
Giordani, F. et al. (2020) Veterinary trypanocidal benzoxaboroles are peptidase-activated prodrugs. PLoS Pathogens, 16(11), e1008932. (doi: 10.1371/journal.ppat.1008932) (PMID:33141865) (PMCID:PMC7710103)
Doleželová, Eva, Kunzová, Michaela, Dejung, Mario, Levin, Michal, Panicucci, Brian, Regnault, Clément, Janzen, Christian J., Barrett, Michael P. ORCID: https://orcid.org/0000-0001-9447-3519, Butter, Falk and Zíková, Alena
(2020)
Cell-based and multi-omics profiling reveals dynamic metabolic repurposing of mitochondria to drive developmental progression of Trypanosoma brucei.
PLoS Biology, 18(6),
e3000741.
(doi: 10.1371/journal.pbio.3000741)
(PMID:32520929)
(PMCID:PMC7307792)
2019
Pountain, Andrew W. ORCID: https://orcid.org/0000-0001-9651-5145, Weidt, Stefan K., Regnault, Clément, Bates, Paul A., Donachie, Anne M., Dickens, Nicholas J.
ORCID: https://orcid.org/0000-0003-0492-5855 and Barrett, Michael P.
ORCID: https://orcid.org/0000-0001-9447-3519
(2019)
Genomic instability at the locus of sterol C24-methyltransferase promotes amphotericin B resistance in Leishmania parasites.
PLoS Neglected Tropical Diseases, 13(2),
e0007052.
(doi: 10.1371/journal.pntd.0007052)
(PMID:30716073)
(PMCID:PMC6375703)
2018
Diaz-Albiter, Hector M., Regnault, Clément, Alpizar-Sosa, Edubiel A., McGuinness, Dagmara ORCID: https://orcid.org/0000-0001-9057-3504, Barrett, Michael P.
ORCID: https://orcid.org/0000-0001-9447-3519 and Dillon, Rod J.
(2018)
Non-invasive visualisation and identification of fluorescent.
Wellcome Open Research, 3,
160.
(doi: 10.12688/wellcomeopenres.14910.1)
(PMID:30756095)
(PMCID:PMC6367660)
Regnault, Clement, Dheeman, Dharmendra and Hochstetter, Axel ORCID: https://orcid.org/0000-0002-2791-2400
(2018)
Microfluidic devices for drug assays.
High-Throughput, 7(2),
18.
(doi: 10.3390/ht7020018)
(PMID:29925804)
(PMCID:29925804)
Rattigan, Kevin M., Pountain, Andrew W. ORCID: https://orcid.org/0000-0001-9651-5145, Regnault, Clement, Achcar, Fiona
ORCID: https://orcid.org/0000-0001-8792-7615, Vincent, Isabel M.
ORCID: https://orcid.org/0000-0003-2663-4389, Goodyear, Carl S.
ORCID: https://orcid.org/0000-0001-5926-5941 and Barrett, Michael P.
ORCID: https://orcid.org/0000-0001-9447-3519
(2018)
Metabolomic profiling of macrophages determines the discrete metabolomic signature and metabolomic interactome triggered by polarising immune stimuli.
PLoS ONE, 13(3),
e0194126.
(doi: 10.1371/journal.pone.0194126)
(PMID:29538444)
(PMCID:PMC5851634)
2017
Barrett, Michael P. ORCID: https://orcid.org/0000-0001-9447-3519, Cooper, Jonathan M.
ORCID: https://orcid.org/0000-0002-2358-1050, Regnault, Clément, Holm, Stefan H., Beech, Jason P., Tegenfeldt, Jonas O. and Hochstetter, Axel
ORCID: https://orcid.org/0000-0002-2791-2400
(2017)
Microfluidics-based approaches to the isolation of African trypanosomes.
Pathogens, 6(4),
47.
(doi: 10.3390/pathogens6040047)
(PMID:28981471)
(PMCID:PMC5750571)
Articles
McCreath, Gordan, Regnault, Clément, Blackburn, Gavin J. ORCID: https://orcid.org/0000-0003-1037-6012, Daly, Rónán
ORCID: https://orcid.org/0000-0002-1275-6820, Leanord, Alistair T., Whitfield, Phillip D.
ORCID: https://orcid.org/0000-0002-0814-4119, Roe, Andrew J.
ORCID: https://orcid.org/0000-0003-3698-6134, Davidson, Alan, Watson, Malcolm J. and Sim, Malcolm A. B.
(2025)
Metabolomics for the diagnosis of secondary infections in critically ill patients with COVID-19.
Critical Care Explorations,
(Accepted for Publication)
Haines, L. R. et al. (2025) Anopheles mosquito survival and pharmacokinetic modeling show the mosquitocidal activity of nitisinone. Science Translational Medicine, 17(791), eadr4827. (doi: 10.1126/scitranslmed.adr4827) (PMID:40138457)
Ilbeigi, K. et al. (2025) Discovery and development of an advanced lead for the treatment of African trypanosomiasis. ACS Infectious Diseases, 11(1), pp. 131-143. (doi: 10.1021/acsinfecdis.4c00472) (PMID:39665421)
Simwela, N. V. et al. (2023) A conserved metabolic signature associated with response to fast-acting anti-malarial agents. Microbiology Spectrum, 11(6), e0397622. (doi: 10.1128/spectrum.03976-22) (PMID:37800971) (PMCID:PMC10714989)
Crozier, L. et al. (2023) CDK4/6 inhibitor-mediated cell overgrowth triggers osmotic and replication stress to promote senescence. Molecular Cell, 83(22), 4062-4077.e5. (doi: 10.1016/j.molcel.2023.10.016) (PMID:37977118)
Năstase, A.-M. et al. (2023) Alignment of multiple metabolomics LC-MS datasets from disparate diseases to reveal fever-associated metabolites. PLoS Neglected Tropical Diseases, 17(7), e0011133. (doi: 10.1371/journal.pntd.0011133) (PMID:37486920) (PMCID:PMC10399774)
O'Brien, Á. C. et al. (2022) Using organic contaminants to constrain the terrestrial journey of the martian meteorite Lafayette. Astrobiology, 22(11), pp. 1351-1362. (doi: 10.1089/ast.2021.0180) (PMID:36264546) (PMCID:PMC9618387)
Apostolopoulou, Natalia G., Smeti, Evangelia, Lamorgese, Marta, Varkitzi, Ioanna, Whitfield, Phillip, Regnault, Clement and Spatharis, Sofie ORCID: https://orcid.org/0000-0003-1030-9821
(2022)
Microalgae show a range of responses to exometabolites of foreign species.
Algal Research, 62,
102627.
(doi: 10.1016/j.algal.2021.102627)
(PMID:35311224)
(PMCID:PMC8924005)
Rubić, I. et al. (2022) Multi platforms strategies and metabolomics approaches for the investigation of comprehensive metabolite profile in dogs with Babesia canis infection. International Journal of Molecular Sciences, 23(3), 1575. (doi: 10.3390/ijms23031575) (PMID:35163517) (PMCID:PMC8835742)
Jara, Marlene, Barrett, Michael ORCID: https://orcid.org/0000-0001-9447-3519, Maes, Ilse, Regnault, Clement, Imamura, Hideo, Domagalska, Malgorzata Anna and Dujardin, Jean-Claude
(2022)
Transcriptional shift and metabolic adaptations during Leishmania quiescence using stationary phase and drug pressure as models.
Microorganisms, 10(1),
97.
(doi: 10.3390/microorganisms10010097)
(PMID:35056546)
(PMCID:PMC8781126)
Milne, K. et al. (2021) Mapping immune variation and var gene switching in naive hosts infected with Plasmodium falciparum. eLife, 10, e62800. (doi: 10.7554/elife.62800) (PMID:33648633) (PMCID:PMC7924948)
Giordani, F. et al. (2020) Veterinary trypanocidal benzoxaboroles are peptidase-activated prodrugs. PLoS Pathogens, 16(11), e1008932. (doi: 10.1371/journal.ppat.1008932) (PMID:33141865) (PMCID:PMC7710103)
Doleželová, Eva, Kunzová, Michaela, Dejung, Mario, Levin, Michal, Panicucci, Brian, Regnault, Clément, Janzen, Christian J., Barrett, Michael P. ORCID: https://orcid.org/0000-0001-9447-3519, Butter, Falk and Zíková, Alena
(2020)
Cell-based and multi-omics profiling reveals dynamic metabolic repurposing of mitochondria to drive developmental progression of Trypanosoma brucei.
PLoS Biology, 18(6),
e3000741.
(doi: 10.1371/journal.pbio.3000741)
(PMID:32520929)
(PMCID:PMC7307792)
Pountain, Andrew W. ORCID: https://orcid.org/0000-0001-9651-5145, Weidt, Stefan K., Regnault, Clément, Bates, Paul A., Donachie, Anne M., Dickens, Nicholas J.
ORCID: https://orcid.org/0000-0003-0492-5855 and Barrett, Michael P.
ORCID: https://orcid.org/0000-0001-9447-3519
(2019)
Genomic instability at the locus of sterol C24-methyltransferase promotes amphotericin B resistance in Leishmania parasites.
PLoS Neglected Tropical Diseases, 13(2),
e0007052.
(doi: 10.1371/journal.pntd.0007052)
(PMID:30716073)
(PMCID:PMC6375703)
Diaz-Albiter, Hector M., Regnault, Clément, Alpizar-Sosa, Edubiel A., McGuinness, Dagmara ORCID: https://orcid.org/0000-0001-9057-3504, Barrett, Michael P.
ORCID: https://orcid.org/0000-0001-9447-3519 and Dillon, Rod J.
(2018)
Non-invasive visualisation and identification of fluorescent.
Wellcome Open Research, 3,
160.
(doi: 10.12688/wellcomeopenres.14910.1)
(PMID:30756095)
(PMCID:PMC6367660)
Regnault, Clement, Dheeman, Dharmendra and Hochstetter, Axel ORCID: https://orcid.org/0000-0002-2791-2400
(2018)
Microfluidic devices for drug assays.
High-Throughput, 7(2),
18.
(doi: 10.3390/ht7020018)
(PMID:29925804)
(PMCID:29925804)
Rattigan, Kevin M., Pountain, Andrew W. ORCID: https://orcid.org/0000-0001-9651-5145, Regnault, Clement, Achcar, Fiona
ORCID: https://orcid.org/0000-0001-8792-7615, Vincent, Isabel M.
ORCID: https://orcid.org/0000-0003-2663-4389, Goodyear, Carl S.
ORCID: https://orcid.org/0000-0001-5926-5941 and Barrett, Michael P.
ORCID: https://orcid.org/0000-0001-9447-3519
(2018)
Metabolomic profiling of macrophages determines the discrete metabolomic signature and metabolomic interactome triggered by polarising immune stimuli.
PLoS ONE, 13(3),
e0194126.
(doi: 10.1371/journal.pone.0194126)
(PMID:29538444)
(PMCID:PMC5851634)
Barrett, Michael P. ORCID: https://orcid.org/0000-0001-9447-3519, Cooper, Jonathan M.
ORCID: https://orcid.org/0000-0002-2358-1050, Regnault, Clément, Holm, Stefan H., Beech, Jason P., Tegenfeldt, Jonas O. and Hochstetter, Axel
ORCID: https://orcid.org/0000-0002-2791-2400
(2017)
Microfluidics-based approaches to the isolation of African trypanosomes.
Pathogens, 6(4),
47.
(doi: 10.3390/pathogens6040047)
(PMID:28981471)
(PMCID:PMC5750571)