Mr Clement Regnault
- Biochemical Data Analyst (MVLS Research Facilities)
email:
Clement.Regnault@glasgow.ac.uk
Room B3.08, Joseph Black Building, University of Glasgow Gilmorehill Campus, University Place, Glasgow, G128QQ
Publications
2025
Haines, L. R. et al. (2025) Anopheles mosquito survival and pharmacokinetic modeling show the mosquitocidal activity of nitisinone. Science Translational Medicine, 17(791), eadr4827. (doi: 10.1126/scitranslmed.adr4827) (PMID:40138457)
2023
Crozier, L. et al. (2023) CDK4/6 inhibitor-mediated cell overgrowth triggers osmotic and replication stress to promote senescence. Molecular Cell, 83(22), 4062-4077.e5. (doi: 10.1016/j.molcel.2023.10.016) (PMID:37977118)
Năstase, A.-M. et al. (2023) Alignment of multiple metabolomics LC-MS datasets from disparate diseases to reveal fever-associated metabolites. PLoS Neglected Tropical Diseases, 17(7), e0011133. (doi: 10.1371/journal.pntd.0011133) (PMID:37486920) (PMCID:PMC10399774)
2022
O'Brien, Á. C. et al. (2022) Using organic contaminants to constrain the terrestrial journey of the martian meteorite Lafayette. Astrobiology, 22(11), pp. 1351-1362. (doi: 10.1089/ast.2021.0180) (PMID:36264546) (PMCID:PMC9618387)
Apostolopoulou, Natalia G., Smeti, Evangelia, Lamorgese, Marta, Varkitzi, Ioanna, Whitfield, Phillip, Regnault, Clement and Spatharis, Sofie ORCID: https://orcid.org/0000-0003-1030-9821
(2022)
Microalgae show a range of responses to exometabolites of foreign species.
Algal Research, 62,
102627.
(doi: 10.1016/j.algal.2021.102627)
(PMID:35311224)
(PMCID:PMC8924005)
Rubić, I. et al. (2022) Multi platforms strategies and metabolomics approaches for the investigation of comprehensive metabolite profile in dogs with Babesia canis infection. International Journal of Molecular Sciences, 23(3), 1575. (doi: 10.3390/ijms23031575) (PMID:35163517) (PMCID:PMC8835742)
Jara, Marlene, Barrett, Michael ORCID: https://orcid.org/0000-0001-9447-3519, Maes, Ilse, Regnault, Clement, Imamura, Hideo, Domagalska, Malgorzata Anna and Dujardin, Jean-Claude
(2022)
Transcriptional shift and metabolic adaptations during Leishmania quiescence using stationary phase and drug pressure as models.
Microorganisms, 10(1),
97.
(doi: 10.3390/microorganisms10010097)
(PMID:35056546)
(PMCID:PMC8781126)
2021
Milne, K. et al. (2021) Mapping immune variation and var gene switching in naive hosts infected with Plasmodium falciparum. eLife, 10, e62800. (doi: 10.7554/elife.62800) (PMID:33648633) (PMCID:PMC7924948)
2020
Giordani, F. et al. (2020) Veterinary trypanocidal benzoxaboroles are peptidase-activated prodrugs. PLoS Pathogens, 16(11), e1008932. (doi: 10.1371/journal.ppat.1008932) (PMID:33141865) (PMCID:PMC7710103)
Doleželová, Eva, Kunzová, Michaela, Dejung, Mario, Levin, Michal, Panicucci, Brian, Regnault, Clément, Janzen, Christian J., Barrett, Michael P. ORCID: https://orcid.org/0000-0001-9447-3519, Butter, Falk and Zíková, Alena
(2020)
Cell-based and multi-omics profiling reveals dynamic metabolic repurposing of mitochondria to drive developmental progression of Trypanosoma brucei.
PLoS Biology, 18(6),
e3000741.
(doi: 10.1371/journal.pbio.3000741)
(PMID:32520929)
(PMCID:PMC7307792)
2019
Pountain, Andrew W. ORCID: https://orcid.org/0000-0001-9651-5145, Weidt, Stefan K., Regnault, Clément, Bates, Paul A., Donachie, Anne M., Dickens, Nicholas J.
ORCID: https://orcid.org/0000-0003-0492-5855 and Barrett, Michael P.
ORCID: https://orcid.org/0000-0001-9447-3519
(2019)
Genomic instability at the locus of sterol C24-methyltransferase promotes amphotericin B resistance in Leishmania parasites.
PLoS Neglected Tropical Diseases, 13(2),
e0007052.
(doi: 10.1371/journal.pntd.0007052)
(PMID:30716073)
(PMCID:PMC6375703)
2018
Diaz-Albiter, Hector M., Regnault, Clément, Alpizar-Sosa, Edubiel A., McGuinness, Dagmara ORCID: https://orcid.org/0000-0001-9057-3504, Barrett, Michael P.
ORCID: https://orcid.org/0000-0001-9447-3519 and Dillon, Rod J.
(2018)
Non-invasive visualisation and identification of fluorescent.
Wellcome Open Research, 3,
160.
(doi: 10.12688/wellcomeopenres.14910.1)
(PMID:30756095)
(PMCID:PMC6367660)
Regnault, Clement, Dheeman, Dharmendra and Hochstetter, Axel ORCID: https://orcid.org/0000-0002-2791-2400
(2018)
Microfluidic devices for drug assays.
High-Throughput, 7(2),
18.
(doi: 10.3390/ht7020018)
(PMID:29925804)
(PMCID:29925804)
Rattigan, Kevin M., Pountain, Andrew W. ORCID: https://orcid.org/0000-0001-9651-5145, Regnault, Clement, Achcar, Fiona
ORCID: https://orcid.org/0000-0001-8792-7615, Vincent, Isabel M.
ORCID: https://orcid.org/0000-0003-2663-4389, Goodyear, Carl S.
ORCID: https://orcid.org/0000-0001-5926-5941 and Barrett, Michael P.
ORCID: https://orcid.org/0000-0001-9447-3519
(2018)
Metabolomic profiling of macrophages determines the discrete metabolomic signature and metabolomic interactome triggered by polarising immune stimuli.
PLoS ONE, 13(3),
e0194126.
(doi: 10.1371/journal.pone.0194126)
(PMID:29538444)
(PMCID:PMC5851634)
2017
Barrett, Michael P. ORCID: https://orcid.org/0000-0001-9447-3519, Cooper, Jonathan M.
ORCID: https://orcid.org/0000-0002-2358-1050, Regnault, Clément, Holm, Stefan H., Beech, Jason P., Tegenfeldt, Jonas O. and Hochstetter, Axel
ORCID: https://orcid.org/0000-0002-2791-2400
(2017)
Microfluidics-based approaches to the isolation of African trypanosomes.
Pathogens, 6(4),
47.
(doi: 10.3390/pathogens6040047)
(PMID:28981471)
(PMCID:PMC5750571)
Articles
Haines, L. R. et al. (2025) Anopheles mosquito survival and pharmacokinetic modeling show the mosquitocidal activity of nitisinone. Science Translational Medicine, 17(791), eadr4827. (doi: 10.1126/scitranslmed.adr4827) (PMID:40138457)
Crozier, L. et al. (2023) CDK4/6 inhibitor-mediated cell overgrowth triggers osmotic and replication stress to promote senescence. Molecular Cell, 83(22), 4062-4077.e5. (doi: 10.1016/j.molcel.2023.10.016) (PMID:37977118)
Năstase, A.-M. et al. (2023) Alignment of multiple metabolomics LC-MS datasets from disparate diseases to reveal fever-associated metabolites. PLoS Neglected Tropical Diseases, 17(7), e0011133. (doi: 10.1371/journal.pntd.0011133) (PMID:37486920) (PMCID:PMC10399774)
O'Brien, Á. C. et al. (2022) Using organic contaminants to constrain the terrestrial journey of the martian meteorite Lafayette. Astrobiology, 22(11), pp. 1351-1362. (doi: 10.1089/ast.2021.0180) (PMID:36264546) (PMCID:PMC9618387)
Apostolopoulou, Natalia G., Smeti, Evangelia, Lamorgese, Marta, Varkitzi, Ioanna, Whitfield, Phillip, Regnault, Clement and Spatharis, Sofie ORCID: https://orcid.org/0000-0003-1030-9821
(2022)
Microalgae show a range of responses to exometabolites of foreign species.
Algal Research, 62,
102627.
(doi: 10.1016/j.algal.2021.102627)
(PMID:35311224)
(PMCID:PMC8924005)
Rubić, I. et al. (2022) Multi platforms strategies and metabolomics approaches for the investigation of comprehensive metabolite profile in dogs with Babesia canis infection. International Journal of Molecular Sciences, 23(3), 1575. (doi: 10.3390/ijms23031575) (PMID:35163517) (PMCID:PMC8835742)
Jara, Marlene, Barrett, Michael ORCID: https://orcid.org/0000-0001-9447-3519, Maes, Ilse, Regnault, Clement, Imamura, Hideo, Domagalska, Malgorzata Anna and Dujardin, Jean-Claude
(2022)
Transcriptional shift and metabolic adaptations during Leishmania quiescence using stationary phase and drug pressure as models.
Microorganisms, 10(1),
97.
(doi: 10.3390/microorganisms10010097)
(PMID:35056546)
(PMCID:PMC8781126)
Milne, K. et al. (2021) Mapping immune variation and var gene switching in naive hosts infected with Plasmodium falciparum. eLife, 10, e62800. (doi: 10.7554/elife.62800) (PMID:33648633) (PMCID:PMC7924948)
Giordani, F. et al. (2020) Veterinary trypanocidal benzoxaboroles are peptidase-activated prodrugs. PLoS Pathogens, 16(11), e1008932. (doi: 10.1371/journal.ppat.1008932) (PMID:33141865) (PMCID:PMC7710103)
Doleželová, Eva, Kunzová, Michaela, Dejung, Mario, Levin, Michal, Panicucci, Brian, Regnault, Clément, Janzen, Christian J., Barrett, Michael P. ORCID: https://orcid.org/0000-0001-9447-3519, Butter, Falk and Zíková, Alena
(2020)
Cell-based and multi-omics profiling reveals dynamic metabolic repurposing of mitochondria to drive developmental progression of Trypanosoma brucei.
PLoS Biology, 18(6),
e3000741.
(doi: 10.1371/journal.pbio.3000741)
(PMID:32520929)
(PMCID:PMC7307792)
Pountain, Andrew W. ORCID: https://orcid.org/0000-0001-9651-5145, Weidt, Stefan K., Regnault, Clément, Bates, Paul A., Donachie, Anne M., Dickens, Nicholas J.
ORCID: https://orcid.org/0000-0003-0492-5855 and Barrett, Michael P.
ORCID: https://orcid.org/0000-0001-9447-3519
(2019)
Genomic instability at the locus of sterol C24-methyltransferase promotes amphotericin B resistance in Leishmania parasites.
PLoS Neglected Tropical Diseases, 13(2),
e0007052.
(doi: 10.1371/journal.pntd.0007052)
(PMID:30716073)
(PMCID:PMC6375703)
Diaz-Albiter, Hector M., Regnault, Clément, Alpizar-Sosa, Edubiel A., McGuinness, Dagmara ORCID: https://orcid.org/0000-0001-9057-3504, Barrett, Michael P.
ORCID: https://orcid.org/0000-0001-9447-3519 and Dillon, Rod J.
(2018)
Non-invasive visualisation and identification of fluorescent.
Wellcome Open Research, 3,
160.
(doi: 10.12688/wellcomeopenres.14910.1)
(PMID:30756095)
(PMCID:PMC6367660)
Regnault, Clement, Dheeman, Dharmendra and Hochstetter, Axel ORCID: https://orcid.org/0000-0002-2791-2400
(2018)
Microfluidic devices for drug assays.
High-Throughput, 7(2),
18.
(doi: 10.3390/ht7020018)
(PMID:29925804)
(PMCID:29925804)
Rattigan, Kevin M., Pountain, Andrew W. ORCID: https://orcid.org/0000-0001-9651-5145, Regnault, Clement, Achcar, Fiona
ORCID: https://orcid.org/0000-0001-8792-7615, Vincent, Isabel M.
ORCID: https://orcid.org/0000-0003-2663-4389, Goodyear, Carl S.
ORCID: https://orcid.org/0000-0001-5926-5941 and Barrett, Michael P.
ORCID: https://orcid.org/0000-0001-9447-3519
(2018)
Metabolomic profiling of macrophages determines the discrete metabolomic signature and metabolomic interactome triggered by polarising immune stimuli.
PLoS ONE, 13(3),
e0194126.
(doi: 10.1371/journal.pone.0194126)
(PMID:29538444)
(PMCID:PMC5851634)
Barrett, Michael P. ORCID: https://orcid.org/0000-0001-9447-3519, Cooper, Jonathan M.
ORCID: https://orcid.org/0000-0002-2358-1050, Regnault, Clément, Holm, Stefan H., Beech, Jason P., Tegenfeldt, Jonas O. and Hochstetter, Axel
ORCID: https://orcid.org/0000-0002-2791-2400
(2017)
Microfluidics-based approaches to the isolation of African trypanosomes.
Pathogens, 6(4),
47.
(doi: 10.3390/pathogens6040047)
(PMID:28981471)
(PMCID:PMC5750571)