Dr Stefan Weidt
- Mass Spectrometry Technologist (MVLS Research Facilities)
telephone:
01413306212
email:
Stefan.Weidt@glasgow.ac.uk
Room B3.08, Joseph Black Building, Gilmorehill Campus, University Place, Glasgow, G12 8QQ
Publications
2024
Cortada Garcia, Joan, Haggarty, Jennifer ORCID: https://orcid.org/0000-0002-5041-8785, Weidt, Stefan, Daly, Rónán
ORCID: https://orcid.org/0000-0002-1275-6820, Arnold, S. Alison and Burgess, Karl
(2024)
On‐line targeted metabolomics for real‐time monitoring of relevant compounds in fermentation processes.
Biotechnology and Bioengineering, 121(2),
pp. 683-695.
(doi: 10.1002/bit.28599)
(PMID:37990977)
(PMCID:PMC10953439)
2023
Rubić, I. et al. (2023) Metabolome profiling in the plasma of dogs with idiopathic dilated cardiomyopathy: a multiplatform mass-spectrometry-based approach. International Journal of Molecular Sciences, 24(20), 15182. (doi: 10.3390/ijms242015182) (PMID:37894863) (PMCID:PMC10607069)
Huang, Yixin, Jonsson, Nicholas N. ORCID: https://orcid.org/0000-0003-3245-9783, McLaughlin, Mark
ORCID: https://orcid.org/0000-0001-5317-2090, Burchmore, Richard
ORCID: https://orcid.org/0000-0003-1663-9004, Johnson, Paul C.D.
ORCID: https://orcid.org/0000-0001-6663-7520, Jones, Rheinallt, McGill, Suzanne, Brady, Nicola, Weidt, Stefan and Eckersall, David
ORCID: https://orcid.org/0000-0001-5254-5502
(2023)
Quantitative TMT-based proteomics revealing host, dietary and microbial proteins in bovine faeces including barley serpin Z4, a prominent component in the head of beer.
Journal of Proteomics, 285,
104941.
(doi: 10.1016/j.jprot.2023.104941)
(PMID:37285906)
McBride, Ross, Wandy, Joe ORCID: https://orcid.org/0000-0002-3068-4664, Weidt, Stefan, Rogers, Simon
ORCID: https://orcid.org/0000-0003-3578-4477, Davies, Vinny
ORCID: https://orcid.org/0000-0003-1896-8936, Daly, Rónán
ORCID: https://orcid.org/0000-0002-1275-6820 and Bryson, Kevin
ORCID: https://orcid.org/0000-0002-1163-6368
(2023)
TopNEXt: automatic DDA exclusion framework for multi-sample mass spectrometry experiments.
Bioinformatics, 39(7),
btad406.
(doi: 10.1093/bioinformatics/btad406)
(PMID:37364005)
Wandy, Joe ORCID: https://orcid.org/0000-0002-3068-4664, Mcbride, Ross, Rogers, Simon
ORCID: https://orcid.org/0000-0003-3578-4477, Terzis, Nikolaos, Weidt, Stefan, van der Hooft, Justin J.J.
ORCID: https://orcid.org/0000-0002-9340-5511, Bryson, Kevin
ORCID: https://orcid.org/0000-0002-1163-6368, Daly, Rónán
ORCID: https://orcid.org/0000-0002-1275-6820 and Davies, Vinny
ORCID: https://orcid.org/0000-0003-1896-8936
(2023)
Simulated-to-real benchmarking of acquisition methods in untargeted metabolomics.
Frontiers in Molecular Biosciences, 10,
1130781.
(doi: 10.3389/fmolb.2023.1130781)
(PMID:36959982)
(PMCID:PMC10027714)
Nguyen, T. X. et al. (2023) Proteomic changes associated with maternal dietary low ω6:ω3 ratio in piglets supplemented with seaweed part I: serum proteomes. Journal of Proteomics, 270, 104740. (doi: 10.1016/j.jprot.2022.104740) (PMID:36191802)
Nguyen, Thi Xuan, Agazzo, Alessandro, McGill, Suzanne, Weidt, Stefan, Han, Quang Hanh, Gelemanović, Andrea, McLaughlin, Mark ORCID: https://orcid.org/0000-0001-5317-2090, Savoini, Giovanni, Eckersall, Peter David
ORCID: https://orcid.org/0000-0001-5254-5502 and Burchmore, Richard
ORCID: https://orcid.org/0000-0003-1663-9004
(2023)
Proteomic changes associated with maternal dietary low ω6:ω3 ratio in piglets supplemented with seaweed part II: ileum proteomes.
Journal of Proteomics, 270,
104739.
(doi: 10.1016/j.jprot.2022.104739)
(PMID:36174954)
2022
Alpizar-Sosa, E. A. et al. (2022) Amphotericin B resistance in Leishmania mexicana: Alterations to sterol metabolism and oxidative stress response. PLoS Neglected Tropical Diseases, 16(9), e0010779. (doi: 10.1371/journal.pntd.0010779) (PMID:36170238) (PMCID:PMC9581426)
Nguyen, T. X. et al. (2022) Abundance of plasma proteins in response to divergent ratios of dietary ω6:ω3 fatty acids in gestating and lactating sows using a quantitative proteomics approach. Journal of Proteomics, 260, 104562. (doi: 10.1016/j.jprot.2022.104562) (PMID:35314360)
Wandy, Joe ORCID: https://orcid.org/0000-0002-3068-4664, Davies, Vinny
ORCID: https://orcid.org/0000-0003-1896-8936, McBride, Ross, Weidt, Stefan, Rogers, Simon
ORCID: https://orcid.org/0000-0003-3578-4477 and Daly, Ronan
ORCID: https://orcid.org/0000-0002-1275-6820
(2022)
ViMMS 2.0: A framework to develop, test and optimise fragmentation strategies in LC-MS metabolomics.
Journal of Open Source Software, 7(71),
3990.
(doi: 10.21105/joss.03990)
Meewan, J. et al. (2022) Limited impact of the protein corona on the cellular uptake of PEGylated zein micelles by melanoma cancer cells. Pharmaceutics, 14(2), e439. (doi: 10.3390/pharmaceutics14020439) (PMID:35214171) (PMCID:PMC8877401)
Rubić, I. et al. (2022) Multi platforms strategies and metabolomics approaches for the investigation of comprehensive metabolite profile in dogs with Babesia canis infection. International Journal of Molecular Sciences, 23(3), 1575. (doi: 10.3390/ijms23031575) (PMID:35163517) (PMCID:PMC8835742)
2021
Davies, Vinny ORCID: https://orcid.org/0000-0003-1896-8936, Wandy, Joe
ORCID: https://orcid.org/0000-0002-3068-4664, Weidt, Stefan, van der Hooft, Justin J.J.
ORCID: https://orcid.org/0000-0002-9340-5511, Miller, Alice
ORCID: https://orcid.org/0000-0002-0941-1717, Daly, Rónán
ORCID: https://orcid.org/0000-0002-1275-6820 and Rogers, Simon
ORCID: https://orcid.org/0000-0003-3578-4477
(2021)
Rapid development of improved data-dependent acquisition strategies.
Analytical Chemistry, 93(14),
pp. 5676-5683.
(doi: 10.1021/acs.analchem.0c03895)
(PMID:33784814)
(PMCID:PMC8047769)
2020
Pesko, Bogumila K., Weidt, Stefan, McLaughlin, Mark ORCID: https://orcid.org/0000-0001-5317-2090, Wescott, Daniel J., Torrance, Hazel, Burgess, Karl and Burchmore, Richard
ORCID: https://orcid.org/0000-0003-1663-9004
(2020)
Post-mortomics: the potential of untargeted metabolomics to highlight markers for time since death.
OMICS: A Journal of Integrative Biology, 24(11),
pp. 649-659.
(doi: 10.1089/omi.2020.0084)
(PMID:33095683)
Burgon, James D. ORCID: https://orcid.org/0000-0002-7035-6614, Vieites, David R., Jacobs, Arne
ORCID: https://orcid.org/0000-0001-7635-5447, Weidt, Stefan K., Gunter, Helen M., Steinfartz, Sebastian, Burgess, Karl, Marble, Barbara K. and Elmer, Kathryn R.
ORCID: https://orcid.org/0000-0002-9219-7001
(2020)
Functional colour genes and signals of selection in colour polymorphic salamanders.
Molecular Ecology, 29(7),
pp. 1284-1299.
(doi: 10.1111/mec.15411)
(PMID:32159878)
2019
Wandy, Joe ORCID: https://orcid.org/0000-0002-3068-4664, Davies, Vinny
ORCID: https://orcid.org/0000-0003-1896-8936, van der Hooft, Justin J.J.
ORCID: https://orcid.org/0000-0002-9340-5511, Weidt, Stefan, Daly, Ronan
ORCID: https://orcid.org/0000-0002-1275-6820 and Rogers, Simon
ORCID: https://orcid.org/0000-0003-3578-4477
(2019)
In silico optimization of mass spectrometry fragmentation strategies in metabolomics.
Metabolites, 9(10),
219.
(doi: 10.3390/metabo9100219)
(PMID:31600991)
Rankin, Naomi J. ORCID: https://orcid.org/0000-0002-7566-1407, Burgess, Karl, Weidt, Stefan, Wannamethee, Goya, Sattar, Naveed
ORCID: https://orcid.org/0000-0002-1604-2593 and Welsh, Paul
ORCID: https://orcid.org/0000-0002-7970-3643
(2019)
High-throughput quantification of carboxymethyl lysine in serum and plasma using high-resolution accurate mass Orbitrap mass spectrometry.
Annals of Clinical Biochemistry, 56(3),
pp. 397-407.
(doi: 10.1177/0004563219830432)
(PMID:30832481)
(PMCID:PMC6498755)
Pountain, Andrew W. ORCID: https://orcid.org/0000-0001-9651-5145, Weidt, Stefan K., Regnault, Clément, Bates, Paul A., Donachie, Anne M., Dickens, Nicholas J.
ORCID: https://orcid.org/0000-0003-0492-5855 and Barrett, Michael P.
ORCID: https://orcid.org/0000-0001-9447-3519
(2019)
Genomic instability at the locus of sterol C24-methyltransferase promotes amphotericin B resistance in Leishmania parasites.
PLoS Neglected Tropical Diseases, 13(2),
e0007052.
(doi: 10.1371/journal.pntd.0007052)
(PMID:30716073)
(PMCID:PMC6375703)
2018
Kovarova, Julie, Pountain, Andrew W. ORCID: https://orcid.org/0000-0001-9651-5145, Wildridge, David, Weidt, Stefan, Bringaud, Frédéric, Burchmore, Richard J.S.
ORCID: https://orcid.org/0000-0003-1663-9004, Achcar, Fiona
ORCID: https://orcid.org/0000-0001-8792-7615 and Barrett, Michael P.
ORCID: https://orcid.org/0000-0001-9447-3519
(2018)
Deletion of transketolase triggers a stringent metabolic response in promastigotes and loss of virulence in amastigotes of Leishmania mexicana.
PLoS Pathogens, 14(3),
e1006953.
(doi: 10.1371/journal.ppat.1006953)
(PMID:29554142)
(PMCID:PMC5882173)
2017
Mwenechanya, R. et al. (2017) Sterol 14α-demethylase mutation leads to amphotericin B resistance in Leishmania mexicana. PLoS Neglected Tropical Diseases, 11(6), e0005649. (doi: 10.1371/journal.pntd.0005649) (PMID:28622334) (PMCID:PMC5498063)
Akpunarlieva, Snezhana, Weidt, Stefan, Lamasudin, Dhilia, Naula, Christina ORCID: https://orcid.org/0000-0003-1165-693X, Henderson, David, Barrett, Michael
ORCID: https://orcid.org/0000-0001-9447-3519, Burgess, Karl and Burchmore, Richard
ORCID: https://orcid.org/0000-0003-1663-9004
(2017)
Integration of proteomics and metabolomics to elucidate metabolic adaptation in Leishmania.
Journal of Proteomics, 155,
pp. 85-98.
(doi: 10.1016/j.jprot.2016.12.009)
(PMID:28040509)
2016
Weidt, Stefan, Haggarty, Jennifer, Kean, Ryan, Cojocariu, Cristian I., Silcock, Paul J., Rajendran, Ranjith, Ramage, Gordon ORCID: https://orcid.org/0000-0002-0932-3514 and Burgess, Karl E. V.
(2016)
A novel targeted/untargeted GC-Orbitrap metabolomics methodology applied to Candida albicans and Staphylococcus aureus biofilms.
Metabolomics, 12,
189.
(doi: 10.1007/s11306-016-1134-2)
(PMID:28003796)
(PMCID:PMC5097782)
Mudaliar, M. et al. (2016) Mastitomics, the integrated omics of bovine milk in an experimental model of Streptococcus uberis mastitis: 2. Label-free relative quantitative proteomics. Molecular BioSystems, 12(9), pp. 2748-2761. (doi: 10.1039/C6MB00290K) (PMID:27412694) (PMCID:PMC5048399)
Meek, S. et al. (2016) Reduced levels of dopamine and altered metabolism in brains of HPRT knock-out rats: a new rodent model of Lesch-Nyhan Disease. Scientific Reports, 6, 25592. (doi: 10.1038/srep25592) (PMID:27185277) (PMCID:PMC4869022)
2015
Haggarty, Jennifer, Oppermann, Madalina, Dalby, Matthew J. ORCID: https://orcid.org/0000-0002-0528-3359, Burchmore, Richard J.
ORCID: https://orcid.org/0000-0003-1663-9004, Cook, Ken, Weidt, Stefan and Burgess, Karl E.V.
(2015)
Serially coupling hydrophobic interaction and reversed-phase chromatography with simultaneous gradients provides greater coverage of the metabolome.
Metabolomics, 11(5),
pp. 1465-1470.
(doi: 10.1007/s11306-014-0770-7)
(PMID:26366140)
(PMCID:PMC4559102)
Creek, D. J. et al. (2015) Probing the metabolic network in bloodstream-form Trypanosoma brucei using untargeted metabolomics with stable isotope labelled glucose. PLoS Pathogens, 11(3), e1004689. (doi: 10.1371/journal.ppat.1004689) (PMID:25775470) (PMCID:PMC4361558)
2014
Vincent, Isabel M. ORCID: https://orcid.org/0000-0003-2663-4389, Weidt, Stefan, Rivas, Luis, Burgess, Karl, Smith, Terry K. and Ouellette, Marc
(2014)
Untargeted metabolomic analysis of miltefosine action in Leishmania infantum reveals changes to the internal lipid metabolism.
International Journal for Parasitology: Drugs and Drug Resistance, 4(1),
pp. 20-27.
(doi: 10.1016/j.ijpddr.2013.11.002)
(PMID:24596665)
(PMCID:PMC3940234)
Burgess, Karl, Rankin, Naomi ORCID: https://orcid.org/0000-0002-7566-1407 and Weidt, Stefan
(2014)
Metabolomics.
In: Padmanabhan, Sandosh (ed.)
Handbook of Pharmacogenomics and Stratified Medicine.
Academic Press: London, pp. 181-205.
ISBN 9780123868824
(doi: 10.1016/B978-0-12-386882-4.00010-4)
Articles
Cortada Garcia, Joan, Haggarty, Jennifer ORCID: https://orcid.org/0000-0002-5041-8785, Weidt, Stefan, Daly, Rónán
ORCID: https://orcid.org/0000-0002-1275-6820, Arnold, S. Alison and Burgess, Karl
(2024)
On‐line targeted metabolomics for real‐time monitoring of relevant compounds in fermentation processes.
Biotechnology and Bioengineering, 121(2),
pp. 683-695.
(doi: 10.1002/bit.28599)
(PMID:37990977)
(PMCID:PMC10953439)
Rubić, I. et al. (2023) Metabolome profiling in the plasma of dogs with idiopathic dilated cardiomyopathy: a multiplatform mass-spectrometry-based approach. International Journal of Molecular Sciences, 24(20), 15182. (doi: 10.3390/ijms242015182) (PMID:37894863) (PMCID:PMC10607069)
Huang, Yixin, Jonsson, Nicholas N. ORCID: https://orcid.org/0000-0003-3245-9783, McLaughlin, Mark
ORCID: https://orcid.org/0000-0001-5317-2090, Burchmore, Richard
ORCID: https://orcid.org/0000-0003-1663-9004, Johnson, Paul C.D.
ORCID: https://orcid.org/0000-0001-6663-7520, Jones, Rheinallt, McGill, Suzanne, Brady, Nicola, Weidt, Stefan and Eckersall, David
ORCID: https://orcid.org/0000-0001-5254-5502
(2023)
Quantitative TMT-based proteomics revealing host, dietary and microbial proteins in bovine faeces including barley serpin Z4, a prominent component in the head of beer.
Journal of Proteomics, 285,
104941.
(doi: 10.1016/j.jprot.2023.104941)
(PMID:37285906)
McBride, Ross, Wandy, Joe ORCID: https://orcid.org/0000-0002-3068-4664, Weidt, Stefan, Rogers, Simon
ORCID: https://orcid.org/0000-0003-3578-4477, Davies, Vinny
ORCID: https://orcid.org/0000-0003-1896-8936, Daly, Rónán
ORCID: https://orcid.org/0000-0002-1275-6820 and Bryson, Kevin
ORCID: https://orcid.org/0000-0002-1163-6368
(2023)
TopNEXt: automatic DDA exclusion framework for multi-sample mass spectrometry experiments.
Bioinformatics, 39(7),
btad406.
(doi: 10.1093/bioinformatics/btad406)
(PMID:37364005)
Wandy, Joe ORCID: https://orcid.org/0000-0002-3068-4664, Mcbride, Ross, Rogers, Simon
ORCID: https://orcid.org/0000-0003-3578-4477, Terzis, Nikolaos, Weidt, Stefan, van der Hooft, Justin J.J.
ORCID: https://orcid.org/0000-0002-9340-5511, Bryson, Kevin
ORCID: https://orcid.org/0000-0002-1163-6368, Daly, Rónán
ORCID: https://orcid.org/0000-0002-1275-6820 and Davies, Vinny
ORCID: https://orcid.org/0000-0003-1896-8936
(2023)
Simulated-to-real benchmarking of acquisition methods in untargeted metabolomics.
Frontiers in Molecular Biosciences, 10,
1130781.
(doi: 10.3389/fmolb.2023.1130781)
(PMID:36959982)
(PMCID:PMC10027714)
Nguyen, T. X. et al. (2023) Proteomic changes associated with maternal dietary low ω6:ω3 ratio in piglets supplemented with seaweed part I: serum proteomes. Journal of Proteomics, 270, 104740. (doi: 10.1016/j.jprot.2022.104740) (PMID:36191802)
Nguyen, Thi Xuan, Agazzo, Alessandro, McGill, Suzanne, Weidt, Stefan, Han, Quang Hanh, Gelemanović, Andrea, McLaughlin, Mark ORCID: https://orcid.org/0000-0001-5317-2090, Savoini, Giovanni, Eckersall, Peter David
ORCID: https://orcid.org/0000-0001-5254-5502 and Burchmore, Richard
ORCID: https://orcid.org/0000-0003-1663-9004
(2023)
Proteomic changes associated with maternal dietary low ω6:ω3 ratio in piglets supplemented with seaweed part II: ileum proteomes.
Journal of Proteomics, 270,
104739.
(doi: 10.1016/j.jprot.2022.104739)
(PMID:36174954)
Alpizar-Sosa, E. A. et al. (2022) Amphotericin B resistance in Leishmania mexicana: Alterations to sterol metabolism and oxidative stress response. PLoS Neglected Tropical Diseases, 16(9), e0010779. (doi: 10.1371/journal.pntd.0010779) (PMID:36170238) (PMCID:PMC9581426)
Nguyen, T. X. et al. (2022) Abundance of plasma proteins in response to divergent ratios of dietary ω6:ω3 fatty acids in gestating and lactating sows using a quantitative proteomics approach. Journal of Proteomics, 260, 104562. (doi: 10.1016/j.jprot.2022.104562) (PMID:35314360)
Wandy, Joe ORCID: https://orcid.org/0000-0002-3068-4664, Davies, Vinny
ORCID: https://orcid.org/0000-0003-1896-8936, McBride, Ross, Weidt, Stefan, Rogers, Simon
ORCID: https://orcid.org/0000-0003-3578-4477 and Daly, Ronan
ORCID: https://orcid.org/0000-0002-1275-6820
(2022)
ViMMS 2.0: A framework to develop, test and optimise fragmentation strategies in LC-MS metabolomics.
Journal of Open Source Software, 7(71),
3990.
(doi: 10.21105/joss.03990)
Meewan, J. et al. (2022) Limited impact of the protein corona on the cellular uptake of PEGylated zein micelles by melanoma cancer cells. Pharmaceutics, 14(2), e439. (doi: 10.3390/pharmaceutics14020439) (PMID:35214171) (PMCID:PMC8877401)
Rubić, I. et al. (2022) Multi platforms strategies and metabolomics approaches for the investigation of comprehensive metabolite profile in dogs with Babesia canis infection. International Journal of Molecular Sciences, 23(3), 1575. (doi: 10.3390/ijms23031575) (PMID:35163517) (PMCID:PMC8835742)
Davies, Vinny ORCID: https://orcid.org/0000-0003-1896-8936, Wandy, Joe
ORCID: https://orcid.org/0000-0002-3068-4664, Weidt, Stefan, van der Hooft, Justin J.J.
ORCID: https://orcid.org/0000-0002-9340-5511, Miller, Alice
ORCID: https://orcid.org/0000-0002-0941-1717, Daly, Rónán
ORCID: https://orcid.org/0000-0002-1275-6820 and Rogers, Simon
ORCID: https://orcid.org/0000-0003-3578-4477
(2021)
Rapid development of improved data-dependent acquisition strategies.
Analytical Chemistry, 93(14),
pp. 5676-5683.
(doi: 10.1021/acs.analchem.0c03895)
(PMID:33784814)
(PMCID:PMC8047769)
Pesko, Bogumila K., Weidt, Stefan, McLaughlin, Mark ORCID: https://orcid.org/0000-0001-5317-2090, Wescott, Daniel J., Torrance, Hazel, Burgess, Karl and Burchmore, Richard
ORCID: https://orcid.org/0000-0003-1663-9004
(2020)
Post-mortomics: the potential of untargeted metabolomics to highlight markers for time since death.
OMICS: A Journal of Integrative Biology, 24(11),
pp. 649-659.
(doi: 10.1089/omi.2020.0084)
(PMID:33095683)
Burgon, James D. ORCID: https://orcid.org/0000-0002-7035-6614, Vieites, David R., Jacobs, Arne
ORCID: https://orcid.org/0000-0001-7635-5447, Weidt, Stefan K., Gunter, Helen M., Steinfartz, Sebastian, Burgess, Karl, Marble, Barbara K. and Elmer, Kathryn R.
ORCID: https://orcid.org/0000-0002-9219-7001
(2020)
Functional colour genes and signals of selection in colour polymorphic salamanders.
Molecular Ecology, 29(7),
pp. 1284-1299.
(doi: 10.1111/mec.15411)
(PMID:32159878)
Wandy, Joe ORCID: https://orcid.org/0000-0002-3068-4664, Davies, Vinny
ORCID: https://orcid.org/0000-0003-1896-8936, van der Hooft, Justin J.J.
ORCID: https://orcid.org/0000-0002-9340-5511, Weidt, Stefan, Daly, Ronan
ORCID: https://orcid.org/0000-0002-1275-6820 and Rogers, Simon
ORCID: https://orcid.org/0000-0003-3578-4477
(2019)
In silico optimization of mass spectrometry fragmentation strategies in metabolomics.
Metabolites, 9(10),
219.
(doi: 10.3390/metabo9100219)
(PMID:31600991)
Rankin, Naomi J. ORCID: https://orcid.org/0000-0002-7566-1407, Burgess, Karl, Weidt, Stefan, Wannamethee, Goya, Sattar, Naveed
ORCID: https://orcid.org/0000-0002-1604-2593 and Welsh, Paul
ORCID: https://orcid.org/0000-0002-7970-3643
(2019)
High-throughput quantification of carboxymethyl lysine in serum and plasma using high-resolution accurate mass Orbitrap mass spectrometry.
Annals of Clinical Biochemistry, 56(3),
pp. 397-407.
(doi: 10.1177/0004563219830432)
(PMID:30832481)
(PMCID:PMC6498755)
Pountain, Andrew W. ORCID: https://orcid.org/0000-0001-9651-5145, Weidt, Stefan K., Regnault, Clément, Bates, Paul A., Donachie, Anne M., Dickens, Nicholas J.
ORCID: https://orcid.org/0000-0003-0492-5855 and Barrett, Michael P.
ORCID: https://orcid.org/0000-0001-9447-3519
(2019)
Genomic instability at the locus of sterol C24-methyltransferase promotes amphotericin B resistance in Leishmania parasites.
PLoS Neglected Tropical Diseases, 13(2),
e0007052.
(doi: 10.1371/journal.pntd.0007052)
(PMID:30716073)
(PMCID:PMC6375703)
Kovarova, Julie, Pountain, Andrew W. ORCID: https://orcid.org/0000-0001-9651-5145, Wildridge, David, Weidt, Stefan, Bringaud, Frédéric, Burchmore, Richard J.S.
ORCID: https://orcid.org/0000-0003-1663-9004, Achcar, Fiona
ORCID: https://orcid.org/0000-0001-8792-7615 and Barrett, Michael P.
ORCID: https://orcid.org/0000-0001-9447-3519
(2018)
Deletion of transketolase triggers a stringent metabolic response in promastigotes and loss of virulence in amastigotes of Leishmania mexicana.
PLoS Pathogens, 14(3),
e1006953.
(doi: 10.1371/journal.ppat.1006953)
(PMID:29554142)
(PMCID:PMC5882173)
Mwenechanya, R. et al. (2017) Sterol 14α-demethylase mutation leads to amphotericin B resistance in Leishmania mexicana. PLoS Neglected Tropical Diseases, 11(6), e0005649. (doi: 10.1371/journal.pntd.0005649) (PMID:28622334) (PMCID:PMC5498063)
Akpunarlieva, Snezhana, Weidt, Stefan, Lamasudin, Dhilia, Naula, Christina ORCID: https://orcid.org/0000-0003-1165-693X, Henderson, David, Barrett, Michael
ORCID: https://orcid.org/0000-0001-9447-3519, Burgess, Karl and Burchmore, Richard
ORCID: https://orcid.org/0000-0003-1663-9004
(2017)
Integration of proteomics and metabolomics to elucidate metabolic adaptation in Leishmania.
Journal of Proteomics, 155,
pp. 85-98.
(doi: 10.1016/j.jprot.2016.12.009)
(PMID:28040509)
Weidt, Stefan, Haggarty, Jennifer, Kean, Ryan, Cojocariu, Cristian I., Silcock, Paul J., Rajendran, Ranjith, Ramage, Gordon ORCID: https://orcid.org/0000-0002-0932-3514 and Burgess, Karl E. V.
(2016)
A novel targeted/untargeted GC-Orbitrap metabolomics methodology applied to Candida albicans and Staphylococcus aureus biofilms.
Metabolomics, 12,
189.
(doi: 10.1007/s11306-016-1134-2)
(PMID:28003796)
(PMCID:PMC5097782)
Mudaliar, M. et al. (2016) Mastitomics, the integrated omics of bovine milk in an experimental model of Streptococcus uberis mastitis: 2. Label-free relative quantitative proteomics. Molecular BioSystems, 12(9), pp. 2748-2761. (doi: 10.1039/C6MB00290K) (PMID:27412694) (PMCID:PMC5048399)
Meek, S. et al. (2016) Reduced levels of dopamine and altered metabolism in brains of HPRT knock-out rats: a new rodent model of Lesch-Nyhan Disease. Scientific Reports, 6, 25592. (doi: 10.1038/srep25592) (PMID:27185277) (PMCID:PMC4869022)
Haggarty, Jennifer, Oppermann, Madalina, Dalby, Matthew J. ORCID: https://orcid.org/0000-0002-0528-3359, Burchmore, Richard J.
ORCID: https://orcid.org/0000-0003-1663-9004, Cook, Ken, Weidt, Stefan and Burgess, Karl E.V.
(2015)
Serially coupling hydrophobic interaction and reversed-phase chromatography with simultaneous gradients provides greater coverage of the metabolome.
Metabolomics, 11(5),
pp. 1465-1470.
(doi: 10.1007/s11306-014-0770-7)
(PMID:26366140)
(PMCID:PMC4559102)
Creek, D. J. et al. (2015) Probing the metabolic network in bloodstream-form Trypanosoma brucei using untargeted metabolomics with stable isotope labelled glucose. PLoS Pathogens, 11(3), e1004689. (doi: 10.1371/journal.ppat.1004689) (PMID:25775470) (PMCID:PMC4361558)
Vincent, Isabel M. ORCID: https://orcid.org/0000-0003-2663-4389, Weidt, Stefan, Rivas, Luis, Burgess, Karl, Smith, Terry K. and Ouellette, Marc
(2014)
Untargeted metabolomic analysis of miltefosine action in Leishmania infantum reveals changes to the internal lipid metabolism.
International Journal for Parasitology: Drugs and Drug Resistance, 4(1),
pp. 20-27.
(doi: 10.1016/j.ijpddr.2013.11.002)
(PMID:24596665)
(PMCID:PMC3940234)
Book Sections
Burgess, Karl, Rankin, Naomi ORCID: https://orcid.org/0000-0002-7566-1407 and Weidt, Stefan
(2014)
Metabolomics.
In: Padmanabhan, Sandosh (ed.)
Handbook of Pharmacogenomics and Stratified Medicine.
Academic Press: London, pp. 181-205.
ISBN 9780123868824
(doi: 10.1016/B978-0-12-386882-4.00010-4)
Research datasets
2025
McBride, R., Weidt, S., Wandy, J. , Davies, V. , Daly, R. and Bryson, K. (2025) Seed .mzML Data for ViMMS Maximum Matching Experiments. [Data Collection]
2022
Wandy, J. , McBride, R., Weidt, S., Rogers, S. , Terzis, N., van der Hooft, J. J. J., Bryson, K. , Daly, R. and Davies, V. (2022) DDA and DIA data for ViMMS 2.0. [Data Collection]
2021
Davies, V. , Wandy, J., Weidt, S., van der Hooft, J., Miller, A. , Daly, R. and Rogers, S. (2021) Rapid Development of Improved Data-Dependent Acquisition Strategies. [Data Collection]
2020
Burgon, J. D., Vieites, D. R., Jacobs, A., Weidt, S., Gunter, H., Steinfartz, S., Burgess, K., Mable, B. and Elmer, K. (2020) Functional colour genes and signals of selection in colour polymorphic salamanders. [Data Collection]
2019
Wandy, J., Davies, V. , van der Hooft, J., Weidt, S., Daly, R. and Rogers, S. (2019) In-silico Optimisation of Mass Spectrometry Fragmentation Strategies in Metabolomics. [Data Collection]