Mrs Margaret Mullin
- Technician (Infection & Immunity Professional Services)
telephone:
0141 330 4893/4431
email:
Margaret.Mullin@glasgow.ac.uk
RA3-33c Level A3, EM Unit CAF College Shared Research Facilities, Joseph Black Building, Glasgow G12 8QQ
Publications
2024
Santi, A. et al. (2024) Cancer-associated fibroblasts produce matrix-bound vesicles that influence endothelial cell function. Science Signaling, (Accepted for Publication)
2023
Wang, H., Manzano, J. S., Kitson, P. J., Mullin, M., Lin, C.-G., Slowing, I. I. and Cronin, L. (2023) Digitizing protocols into single reactors for the one-pot synthesis of nanomaterials. Matter, 6(7), pp. 2383-2394. (doi: 10.1016/j.matt.2023.05.029)
2022
Naylor, G., Julian, L., Watson-Bryce, S., Mullin, M., Nibbs, R. J. and Olson, M. F. (2022) Immunogenic death of hepatocellular carcinoma cells in mice expressing caspase-resistant ROCK1 is not replicated by ROCK inhibitors. Cancers, 14(23), 5943. (doi: 10.3390/cancers14235943) (PMID:36497425) (PMCID:PMC9740421)
Haney, J., Vijayakrishnan, S. , Streetley, J. , Dee, K., Goldfarb, D. M., Clarke, M. , Mullin, M., Carter, S. D. , Bhella, D. and Murcia, P. R. (2022) Coinfection by influenza A virus and respiratory syncytial virus produces hybrid virus particles. Nature Microbiology, 7(11), pp. 1879-1890. (doi: 10.1038/s41564-022-01242-5) (PMID:36280786)
Meewan, J. et al. (2022) Limited impact of the protein corona on the cellular uptake of PEGylated zein micelles by melanoma cancer cells. Pharmaceutics, 14(2), e439. (doi: 10.3390/pharmaceutics14020439) (PMID:35214171) (PMCID:PMC8877401)
Meewan, J., Somani, S., Almowalad, J., Laskar, P., Mullin, M., MacKenzie, G., Khadke, S., Perrie, Y. and Dufès, C. (2022) Preparation of zein-based nanoparticles: nanoprecipitation versus microfluidic-assisted manufacture, effects of PEGylation on nanoparticle characteristics and cellular uptake by melanoma cells. International Journal of Nanomedicine, 17, pp. 2809-2822. (doi: 10.2147/IJN.S366138) (PMID:35791309) (PMCID:PMC9250780)
2021
Schultz, V. et al. (2021) Oligodendrocytes are susceptible to Zika virus infection in a mouse model of perinatal exposure: implications for CNS complications. Glia, 69(8), pp. 2023-2036. (doi: 10.1002/glia.24010) (PMID:33942402) (PMCID:PMC9216243)
Laskar, P., Somani, S., Mullin, M., Tate, R. J., Warzecha, M., Bowering, D., Keating, P., Irving, C., Leung, H. Y. and Dufès, C. (2021) Octadecyl chain-bearing PEGylated poly(propyleneimine)-based dendrimersomes: physicochemical studies, redox-responsiveness, DNA condensation, cytotoxicity and gene delivery to cancer cells. Biomaterials Science, 9(4), pp. 1431-1448. (doi: 10.1039/D0BM01441A) (PMID:33404026)
2020
Roca Portoles, A., Blanco, G., Sumpton, D., Cloix, C., Mullin, M., Mackay, G. M., O'Neill, K., Lemgruber Soares, L. , Luo, X. and Tait, S. W.G. (2020) Venetoclax causes metabolic reprogramming independent of BCL-2 inhibition. Cell Death and Disease, 11, 616. (doi: 10.1038/s41419-020-02867-2) (PMID:32792521) (PMCID:PMC7426836)
Sakpakdeejaroen, I., Somani, S., Mullin, M. and Dufès, C. (2020) Development of transferrin-bearing vesicles encapsulating aspirin for cancer therapy. Journal of Liposome Research, 30(2), pp. 174-181. (doi: 10.1080/08982104.2019.1614054) (PMID:31060409)
2019
Laskar, P., Somani, S., Campbell, S. J., Mullin, M., Keating, P., Tate, R. J., Irving, C., Leung, H. Y. and Dufès, C. (2019) Camptothecin-based dendrimersomes for gene delivery and redox-responsive drug delivery to cancer cells. Nanoscale, 11(42), pp. 20058-20071. (doi: 10.1039/C9NR07254C) (PMID:31612185)
Rudzka, D. A. et al. (2019) Migration through physical constraints is enabled by MAPK-induced cell softening via actin cytoskeleton re-organization. Journal of Cell Science, 132(11), jcs224071. (doi: 10.1242/jcs.224071) (PMID:31152052) (PMCID:PMC6589089)
Surman, A. J. , Rodriguez Garcia, M., Abul-Haija, Y. M. , Cooper, G. J.T. , Gromski, P. S., Turk-MacLeod, R., Mullin, M., Mathis, C., Walker, S. I. and Cronin, L. (2019) Environmental control programs the emergence of distinct functional ensembles from unconstrained chemical reactions. Proceedings of the National Academy of Sciences of the United States of America, 116(12), pp. 5387-5392. (doi: 10.1073/pnas.1813987116) (PMID:30842280) (PMCID:PMC6431231)
2018
Mccully, M., Conde, J., Baptista, P. V., Mullin, M., Dalby, M. J. and Berry, C. C. (2018) Nanoparticle-antagomiR based targeting of miR-31 to induce osterix and osteocalcin expression in mesenchymal stem cells. PLoS ONE, 13(2), e0192562. (doi: 10.1371/journal.pone.0192562) (PMID:29444183) (PMCID:PMC5812622)
2017
Surman, A. J. , Rodriguez-Garcia, M., Abul-Haija, Y. , Cooper, G. J.T. , Donkers, K., Planchat i Barbarà, J. M., Kube, J., Mullin, M., Hezwani, M. and Cronin, L. (2017) Can a Reaction's Environment Program its Outcome, and Does it Matter? In: XVIIIth International Conference on the Origin of Life (LPI Contribution No. 1967), San Diego, CA, USA, 16-21 Jul 2017, p. 4006.
Rath, N. et al. (2017) ROCK signaling promotes collagen remodeling to facilitate invasive pancreatic ductal adenocarcinoma tumor cell growth. EMBO Molecular Medicine, 9(2), pp. 198-218. (doi: 10.15252/emmm.201606743) (PMID:28031255) (PMCID:PMC5286371)
Karim, R., Somani, S., Al Robaian, M., Mullin, M., Amor, R., McConnell, G. and Dufès, C. (2017) Tumor regression after intravenous administration of targeted vesicles entrapping the vitamin E α-tocotrienol. Journal of Controlled Release, 246, pp. 79-87. (doi: 10.1016/j.jconrel.2016.12.014) (PMID:27993600)
Lewis, N. S., Lewis, E. E.L., Mullin, M., Wheadon, H. , Dalby, M. J. and Berry, C. C. (2017) Magnetically levitated mesenchymal stem cell spheroids cultured with a collagen gel maintain phenotype and quiescence. Journal of Tissue Engineering, 8, pp. 1-11. (doi: 10.1177/2041731417704428) (PMID:28616152) (PMCID:PMC5460809)
Weigert, M. et al. (2017) RIPK3 promotes adenovirus type 5 activity. Cell Death and Disease, 8, 3206. (doi: 10.1038/s41419-017-0110-8) (PMID:29238045) (PMCID:PMC5870599)
2016
Lewis, E. E. L., Wheadon, H. , Lewis, N., Yang, J., Mullin, M., Hursthouse, A., Stirling, D., Dalby, M. J. and Berry, C. C. (2016) A quiescent, regeneration-responsive tissue engineered mesenchymal stem cell bone marrow niche model via magnetic levitation. ACS Nano, 10(9), pp. 8346-8354. (doi: 10.1021/acsnano.6b02841) (PMID:27602872)
Raghupathy, R. K., Zhang, X., Alhasani, R. H., Zhou, X., Mullin, M., Reilly, J., Li, W., Liu, M. and Shu, X. (2016) Abnormal photoreceptor outer segment development and early retinal degeneration in kif3a mutant zebrafish. Cell Biochemistry and Function, 34(6), pp. 429-440. (doi: 10.1002/cbf.3205) (PMID:27470972)
2015
Child, H. W., Hernandez, Y., Conde, J., Mullin, M., Baptista, P., de la Fuente, J. M. and Berry, C. (2015) Gold nanoparticle-siRNA mediated oncogene knockdown at RNA and protein level, with associated gene effects. Nanomedicine, 10(16), pp. 2513-2525. (doi: 10.2217/NNM.15.95) (PMID:26302331)
Lewis, E. E.L., Child, H. W., Hursthouse, A., Stirling, D., McCully, M., Paterson, D., Mullin, M. and Berry, C. C. (2015) The influence of particle size and static magnetic fields on the uptake of magnetic nanoparticles into three dimensional cell-seeded collagen gel cultures. Journal of Biomedical Materials Research Part B: Applied Biomaterials, 103(6), pp. 1294-1301. (doi: 10.1002/jbm.b.33302)
Lim, L. Y. et al. (2015) Tumor regression following intravenous administration of lactoferrin- and lactoferricin-bearing dendriplexes. Nanomedicine: Nanotechnology, Biology and Medicine, 11(6), pp. 1445-1454. (doi: 10.1016/j.nano.2015.04.006) (PMID:25933695) (PMCID:PMC4509555)
2010
Haddock, G., Mullin, M., MacCallum, A., Sherry, A. , Tetley, L., Watson, E., Dagleish, M., Smith, D. G.E. and Everest, P. (2010) Campylobacter jejuni 81-176 forms distinct microcolonies on in vitro-infected human small intestinal tissue prior to biofilm formation. Microbiology, 156(10), p. 3079. (doi: 10.1099/mic.0.039867-0) (PMID:20616103)
2009
Hancock, G. E., Hewitt, S. M., Godfrey, A. and Mullin, M. (2009) Thoracic spiracular gill structure of Lipsothrix (Diptera, Limoniidae) in Britain described from scanning electron micrographs. Zoosymposia, 3, pp. 77-87.
Articles
Santi, A. et al. (2024) Cancer-associated fibroblasts produce matrix-bound vesicles that influence endothelial cell function. Science Signaling, (Accepted for Publication)
Wang, H., Manzano, J. S., Kitson, P. J., Mullin, M., Lin, C.-G., Slowing, I. I. and Cronin, L. (2023) Digitizing protocols into single reactors for the one-pot synthesis of nanomaterials. Matter, 6(7), pp. 2383-2394. (doi: 10.1016/j.matt.2023.05.029)
Naylor, G., Julian, L., Watson-Bryce, S., Mullin, M., Nibbs, R. J. and Olson, M. F. (2022) Immunogenic death of hepatocellular carcinoma cells in mice expressing caspase-resistant ROCK1 is not replicated by ROCK inhibitors. Cancers, 14(23), 5943. (doi: 10.3390/cancers14235943) (PMID:36497425) (PMCID:PMC9740421)
Haney, J., Vijayakrishnan, S. , Streetley, J. , Dee, K., Goldfarb, D. M., Clarke, M. , Mullin, M., Carter, S. D. , Bhella, D. and Murcia, P. R. (2022) Coinfection by influenza A virus and respiratory syncytial virus produces hybrid virus particles. Nature Microbiology, 7(11), pp. 1879-1890. (doi: 10.1038/s41564-022-01242-5) (PMID:36280786)
Meewan, J. et al. (2022) Limited impact of the protein corona on the cellular uptake of PEGylated zein micelles by melanoma cancer cells. Pharmaceutics, 14(2), e439. (doi: 10.3390/pharmaceutics14020439) (PMID:35214171) (PMCID:PMC8877401)
Meewan, J., Somani, S., Almowalad, J., Laskar, P., Mullin, M., MacKenzie, G., Khadke, S., Perrie, Y. and Dufès, C. (2022) Preparation of zein-based nanoparticles: nanoprecipitation versus microfluidic-assisted manufacture, effects of PEGylation on nanoparticle characteristics and cellular uptake by melanoma cells. International Journal of Nanomedicine, 17, pp. 2809-2822. (doi: 10.2147/IJN.S366138) (PMID:35791309) (PMCID:PMC9250780)
Schultz, V. et al. (2021) Oligodendrocytes are susceptible to Zika virus infection in a mouse model of perinatal exposure: implications for CNS complications. Glia, 69(8), pp. 2023-2036. (doi: 10.1002/glia.24010) (PMID:33942402) (PMCID:PMC9216243)
Laskar, P., Somani, S., Mullin, M., Tate, R. J., Warzecha, M., Bowering, D., Keating, P., Irving, C., Leung, H. Y. and Dufès, C. (2021) Octadecyl chain-bearing PEGylated poly(propyleneimine)-based dendrimersomes: physicochemical studies, redox-responsiveness, DNA condensation, cytotoxicity and gene delivery to cancer cells. Biomaterials Science, 9(4), pp. 1431-1448. (doi: 10.1039/D0BM01441A) (PMID:33404026)
Roca Portoles, A., Blanco, G., Sumpton, D., Cloix, C., Mullin, M., Mackay, G. M., O'Neill, K., Lemgruber Soares, L. , Luo, X. and Tait, S. W.G. (2020) Venetoclax causes metabolic reprogramming independent of BCL-2 inhibition. Cell Death and Disease, 11, 616. (doi: 10.1038/s41419-020-02867-2) (PMID:32792521) (PMCID:PMC7426836)
Sakpakdeejaroen, I., Somani, S., Mullin, M. and Dufès, C. (2020) Development of transferrin-bearing vesicles encapsulating aspirin for cancer therapy. Journal of Liposome Research, 30(2), pp. 174-181. (doi: 10.1080/08982104.2019.1614054) (PMID:31060409)
Laskar, P., Somani, S., Campbell, S. J., Mullin, M., Keating, P., Tate, R. J., Irving, C., Leung, H. Y. and Dufès, C. (2019) Camptothecin-based dendrimersomes for gene delivery and redox-responsive drug delivery to cancer cells. Nanoscale, 11(42), pp. 20058-20071. (doi: 10.1039/C9NR07254C) (PMID:31612185)
Rudzka, D. A. et al. (2019) Migration through physical constraints is enabled by MAPK-induced cell softening via actin cytoskeleton re-organization. Journal of Cell Science, 132(11), jcs224071. (doi: 10.1242/jcs.224071) (PMID:31152052) (PMCID:PMC6589089)
Surman, A. J. , Rodriguez Garcia, M., Abul-Haija, Y. M. , Cooper, G. J.T. , Gromski, P. S., Turk-MacLeod, R., Mullin, M., Mathis, C., Walker, S. I. and Cronin, L. (2019) Environmental control programs the emergence of distinct functional ensembles from unconstrained chemical reactions. Proceedings of the National Academy of Sciences of the United States of America, 116(12), pp. 5387-5392. (doi: 10.1073/pnas.1813987116) (PMID:30842280) (PMCID:PMC6431231)
Mccully, M., Conde, J., Baptista, P. V., Mullin, M., Dalby, M. J. and Berry, C. C. (2018) Nanoparticle-antagomiR based targeting of miR-31 to induce osterix and osteocalcin expression in mesenchymal stem cells. PLoS ONE, 13(2), e0192562. (doi: 10.1371/journal.pone.0192562) (PMID:29444183) (PMCID:PMC5812622)
Rath, N. et al. (2017) ROCK signaling promotes collagen remodeling to facilitate invasive pancreatic ductal adenocarcinoma tumor cell growth. EMBO Molecular Medicine, 9(2), pp. 198-218. (doi: 10.15252/emmm.201606743) (PMID:28031255) (PMCID:PMC5286371)
Karim, R., Somani, S., Al Robaian, M., Mullin, M., Amor, R., McConnell, G. and Dufès, C. (2017) Tumor regression after intravenous administration of targeted vesicles entrapping the vitamin E α-tocotrienol. Journal of Controlled Release, 246, pp. 79-87. (doi: 10.1016/j.jconrel.2016.12.014) (PMID:27993600)
Lewis, N. S., Lewis, E. E.L., Mullin, M., Wheadon, H. , Dalby, M. J. and Berry, C. C. (2017) Magnetically levitated mesenchymal stem cell spheroids cultured with a collagen gel maintain phenotype and quiescence. Journal of Tissue Engineering, 8, pp. 1-11. (doi: 10.1177/2041731417704428) (PMID:28616152) (PMCID:PMC5460809)
Weigert, M. et al. (2017) RIPK3 promotes adenovirus type 5 activity. Cell Death and Disease, 8, 3206. (doi: 10.1038/s41419-017-0110-8) (PMID:29238045) (PMCID:PMC5870599)
Lewis, E. E. L., Wheadon, H. , Lewis, N., Yang, J., Mullin, M., Hursthouse, A., Stirling, D., Dalby, M. J. and Berry, C. C. (2016) A quiescent, regeneration-responsive tissue engineered mesenchymal stem cell bone marrow niche model via magnetic levitation. ACS Nano, 10(9), pp. 8346-8354. (doi: 10.1021/acsnano.6b02841) (PMID:27602872)
Raghupathy, R. K., Zhang, X., Alhasani, R. H., Zhou, X., Mullin, M., Reilly, J., Li, W., Liu, M. and Shu, X. (2016) Abnormal photoreceptor outer segment development and early retinal degeneration in kif3a mutant zebrafish. Cell Biochemistry and Function, 34(6), pp. 429-440. (doi: 10.1002/cbf.3205) (PMID:27470972)
Child, H. W., Hernandez, Y., Conde, J., Mullin, M., Baptista, P., de la Fuente, J. M. and Berry, C. (2015) Gold nanoparticle-siRNA mediated oncogene knockdown at RNA and protein level, with associated gene effects. Nanomedicine, 10(16), pp. 2513-2525. (doi: 10.2217/NNM.15.95) (PMID:26302331)
Lewis, E. E.L., Child, H. W., Hursthouse, A., Stirling, D., McCully, M., Paterson, D., Mullin, M. and Berry, C. C. (2015) The influence of particle size and static magnetic fields on the uptake of magnetic nanoparticles into three dimensional cell-seeded collagen gel cultures. Journal of Biomedical Materials Research Part B: Applied Biomaterials, 103(6), pp. 1294-1301. (doi: 10.1002/jbm.b.33302)
Lim, L. Y. et al. (2015) Tumor regression following intravenous administration of lactoferrin- and lactoferricin-bearing dendriplexes. Nanomedicine: Nanotechnology, Biology and Medicine, 11(6), pp. 1445-1454. (doi: 10.1016/j.nano.2015.04.006) (PMID:25933695) (PMCID:PMC4509555)
Haddock, G., Mullin, M., MacCallum, A., Sherry, A. , Tetley, L., Watson, E., Dagleish, M., Smith, D. G.E. and Everest, P. (2010) Campylobacter jejuni 81-176 forms distinct microcolonies on in vitro-infected human small intestinal tissue prior to biofilm formation. Microbiology, 156(10), p. 3079. (doi: 10.1099/mic.0.039867-0) (PMID:20616103)
Hancock, G. E., Hewitt, S. M., Godfrey, A. and Mullin, M. (2009) Thoracic spiracular gill structure of Lipsothrix (Diptera, Limoniidae) in Britain described from scanning electron micrographs. Zoosymposia, 3, pp. 77-87.
Conference Proceedings
Surman, A. J. , Rodriguez-Garcia, M., Abul-Haija, Y. , Cooper, G. J.T. , Donkers, K., Planchat i Barbarà, J. M., Kube, J., Mullin, M., Hezwani, M. and Cronin, L. (2017) Can a Reaction's Environment Program its Outcome, and Does it Matter? In: XVIIIth International Conference on the Origin of Life (LPI Contribution No. 1967), San Diego, CA, USA, 16-21 Jul 2017, p. 4006.