Mr Ryan McChrystal
- Research Assistant (Cardiovascular & Metabolic Health)
Publications
2025
Hanlon, P. et al. (2025) Assessing the representativeness of trials of sodium-glucose cotransporter-2 inhibitors in type 2 diabetes: a comparison of individual-level trial data and people newly prescribed treatment in a Welsh routine care database. BMC Medicine, 23(1), 661. (doi: 10.1186/s12916-025-04492-2) (PMID:41299446) (PMCID:PMC12659586)
McChrystal, Ryan, Hanlon, Peter 
ORCID: https://orcid.org/0000-0002-5828-3934, Lees, Jennifer S. ORCID: https://orcid.org/0000-0001-6331-0178, Phillippo, David M., Welton, Nicky J., Gillies, Katie and McAllister, David ORCID: https://orcid.org/0000-0003-3550-1764
(2025)
Modelling rates of trial attrition: an analysis of individual participant data from 90 randomized controlled trials of pharmacological interventions for multiple conditions.
Journal of Clinical Epidemiology, 187,
111971.
(doi: 10.1016/j.jclinepi.2025.111971)
(PMID:40921288)
Wightman, H. et al. (2025) Frailty in randomized controlled trials of glucose-lowering therapies for type 2 diabetes: An individual participant data meta-analysis of frailty prevalence, treatment efficacy, and adverse events. PLoS Medicine, 22(4), e1004553. (doi: 10.1371/journal.pmed.1004553) (PMID:40193407)
Hanlon, P. et al. (2025) Age and sex differences in efficacy of treatments for type 2 diabetes: a network meta-analysis. JAMA: Journal of the American Medical Association, 333(12), pp. 1062-1073. (doi: 10.1001/jama.2024.27402) (PMID:39899304) (PMCID:PMC11791772)
McChrystal, Ryan, Lees, Jennifer ORCID: https://orcid.org/0000-0001-6331-0178, Gillies, Katie, McAllister, David ORCID: https://orcid.org/0000-0003-3550-1764 and Hanlon, Peter ORCID: https://orcid.org/0000-0002-5828-3934
(2025)
Participant and trial characteristics reported in predictive analyses of trial attrition: an umbrella review of systematic reviews of randomised controlled trials across multiple conditions.
Trials, 26,
84.
(doi: 10.1186/s13063-025-08794-x)
(PMID:40075486)
Articles
Hanlon, P. et al. (2025) Assessing the representativeness of trials of sodium-glucose cotransporter-2 inhibitors in type 2 diabetes: a comparison of individual-level trial data and people newly prescribed treatment in a Welsh routine care database. BMC Medicine, 23(1), 661. (doi: 10.1186/s12916-025-04492-2) (PMID:41299446) (PMCID:PMC12659586)
McChrystal, Ryan, Hanlon, Peter ORCID: https://orcid.org/0000-0002-5828-3934, Lees, Jennifer S. ORCID: https://orcid.org/0000-0001-6331-0178, Phillippo, David M., Welton, Nicky J., Gillies, Katie and McAllister, David ORCID: https://orcid.org/0000-0003-3550-1764
(2025)
Modelling rates of trial attrition: an analysis of individual participant data from 90 randomized controlled trials of pharmacological interventions for multiple conditions.
Journal of Clinical Epidemiology, 187,
111971.
(doi: 10.1016/j.jclinepi.2025.111971)
(PMID:40921288)
Wightman, H. et al. (2025) Frailty in randomized controlled trials of glucose-lowering therapies for type 2 diabetes: An individual participant data meta-analysis of frailty prevalence, treatment efficacy, and adverse events. PLoS Medicine, 22(4), e1004553. (doi: 10.1371/journal.pmed.1004553) (PMID:40193407)
Hanlon, P. et al. (2025) Age and sex differences in efficacy of treatments for type 2 diabetes: a network meta-analysis. JAMA: Journal of the American Medical Association, 333(12), pp. 1062-1073. (doi: 10.1001/jama.2024.27402) (PMID:39899304) (PMCID:PMC11791772)
McChrystal, Ryan, Lees, Jennifer ORCID: https://orcid.org/0000-0001-6331-0178, Gillies, Katie, McAllister, David ORCID: https://orcid.org/0000-0003-3550-1764 and Hanlon, Peter ORCID: https://orcid.org/0000-0002-5828-3934
(2025)
Participant and trial characteristics reported in predictive analyses of trial attrition: an umbrella review of systematic reviews of randomised controlled trials across multiple conditions.
Trials, 26,
84.
(doi: 10.1186/s13063-025-08794-x)
(PMID:40075486)