Dr Giacomo Rossitto
- Honorary Research Fellow (School of Cardiovascular & Metabolic Health)
Publications
2024
Rossi, G. P., Bagordo, D., Rossi, F. B., Pintus, G., Rossitto, G. and Seccia, T. M. (2024) ‘Essential’ arterial hypertension: time for a paradigm change. Journal of Hypertension, 42(8), pp. 1298-1304. (doi: 10.1097/hjh.0000000000003767) (PMID:38748508) (PMCID:PMC11216381)
Rossitto, G., Bertoldi, G., Rutkowski, J. M., Mitchell, B. M. and Delles, C. (2024) Sodium, interstitium, lymphatics, and hypertension - A tale of hydraulics. Hypertension, 81(4), pp. 727-737. (doi: 10.1161/HYPERTENSIONAHA.123.17942) (PMID:38385255)
2023
Bagordo, D., Rossi, G. P., Delles, C. , Wiig, H. and Rossitto, G. (2023) The tangram of sodium and fluid balance: salt series. Hypertension, (doi: 10.1161/HYPERTENSIONAHA.123.19569) (Early Online Publication)
Zhu, R., Shagjaa, T., Rossitto, G., Caroccia, B., Seccia, T. M., Gregori, D. and Rossi, G. P. (2023) Exclusion tests in unilateral primary aldosteronism (ExcluPA) study. Journal of Clinical Endocrinology and Metabolism, 108(2), pp. 496-506. (doi: 10.1210/clinem/dgac654) (PMID:36373399)
2022
Chen, J. Y., Chew, K. S., Mary, S. , Boder, P., Bagordo, D., Rossi, G. P., Touyz, R. M. , Delles, C. and Rossitto, G. (2022) Skin-specific mechanisms of body fluid regulation in hypertension. Clinical Science, 137(3), pp. 239-250. (doi: 10.1042/CS20220609) (PMID:36648486)
Rossitto, G. and Delles, C. (2022) Mechanisms of sodium-mediated injury in cardiovascular disease: old play, new scripts. FEBS Journal, 289(23), pp. 7260-7273. (doi: 10.1111/febs.16155) (PMID:34355504)
Mary, S. , Rossitto, G. and Delles, C. (2022) Pathophysiology of hypertension. In: Nadar, Sunil and Lip, Gregory (eds.) Hypertension. Series: Oxford cardiology library. Oxford University Press: Oxford, pp. 11-20. ISBN 9780198870678 (doi: 10.1093/med/9780198870678.003.0002)
Rossi, G. P. and Rossitto, G. (2022) Aldosterone and cardiovascular damage: a new lesson from an old study. Hypertension, 79(9), pp. 1994-1996. (doi: 10.1161/hypertensionaha.122.19662) (PMID:35947644)
Sanga, V., Rossitto, G., Seccia, T. M. and Rossi, G. P. (2022) Management and outcomes of primary aldosteronism in pregnancy: a systematic review. Hypertension, 79(9), pp. 1912-1921. (doi: 10.1161/HYPERTENSIONAHA.121.18858) (PMID:35686552)
Rossitto, G. and Delles, C. (2022) Does excess tissue sodium storage regulate blood pressure? Current Hypertension Reports, 24(5), pp. 115-122. (doi: 10.1007/s11906-022-01180-x) (PMID:35192140) (PMCID:PMC9142429)
Rossi, G. P. et al. (2022) Drug-resistant hypertension in primary aldosteronism patients undergoing adrenal vein sampling: the AVIS-2-RH study. European Journal of Preventive Cardiology, 29(2), e85-e93. (doi: 10.1093/eurjpc/zwaa108) (PMID:33742213)
Delles, C. and Rossitto, G. (2022) Of snails, earthworms, and men: insights into strategies to preserve water. Function, 3(1), zqab071. (doi: 10.1093/function/zqab071) (PMID:35330922) (PMCID:PMC8788808)
2021
Mary, S. , Boder, P., Rossitto, G., Graham, L. , Scott, K., Flynn, A., Kipgen, D., Graham, D. and Delles, C. (2021) Salt loading decreases urinary excretion and increases intracellular accumulation of uromodulin in stroke-prone spontaneously hypertensive rats. Clinical Science, 135(24), pp. 2749-2761. (doi: 10.1042/CS20211017) (PMID:34870708) (PMCID:PMC8689196)
Rossi, G. P. et al. (2021) Feasibility of imaging-guided adrenalectomy in young patients with primary aldosteronism. Hypertension, 79(1), pp. 187-195. (doi: 10.1161/HYPERTENSIONAHA.121.18284) (PMID:34878892)
Murray, E. , Rossitto, G. and Delles, C. (2021) Haemodynamic assessment in hypertension: the soloists and the orchestra. Journal of Hypertension, 39(6), pp. 1109-1111. (doi: 10.1097/HJH.0000000000002796) (PMID:33967215)
Rossitto, G. et al. (2021) High sodium intake, glomerular hyperfiltration and protein catabolism in patients with essential hypertension. Cardiovascular Research, 117(5), pp. 1372-1381. (doi: 10.1093/cvr/cvaa205) (PMID:33053160) (PMCID:PMC8064429)
2020
Rossitto, G. et al. (2020) Reduced lymphatic reserve in heart failure with preserved ejection fraction. Journal of the American College of Cardiology, 76(24), pp. 2817-2829. (doi: 10.1016/j.jacc.2020.10.022) (PMID:33303070) (PMCID:PMC7724570)
Rossitto, G. et al. (2020) Tissue sodium excess is not hypertonic and reflects extracellular volume expansion. Nature Communications, 11, 4222. (doi: 10.1038/s41467-020-17820-2) (PMID:32839436) (PMCID:PMC7445299)
Rossitto, G. et al. (2020) Subtyping of primary aldosteronism in the AVIS-2 study: assessment of selectivity and lateralization. Journal of Clinical Endocrinology and Metabolism, 105(6), pp. 2042-2052. (doi: 10.1210/clinem/dgz017) (PMID:31536622)
2019
Rossi, G. P. et al. (2019) Clinical outcomes of 1625 patients with primary aldosteronism subtyped with adrenal vein sampling. Hypertension, 74(4), pp. 800-808. (doi: 10.1161/HYPERTENSIONAHA.119.13463) (PMID:31476901)
Cameron, A. C., Rossitto, G., Lang, N. N. and Touyz, R. M. (2019) Antihypertensive drugs and vascular health. In: Zimlichman, Reuven, Julius, Stevo and Mancia, Giuseppe (eds.) Prehypertension and Cardiometabolic Syndrome. Series: Updates in hypertension and cardiovascular protection. Springer, pp. 585-605. ISBN 9783319753096 (doi: 10.1007/978-3-319-75310-2_37)
Rossitto, G., Sneddon, M. and Rockson, S. G. (2019) The lymphatic system. In: Touyz, Rhian M. and Delles, Christian (eds.) Textbook of Vascular Medicine. Springer: Cham, pp. 45-57. ISBN 9783030164805 (doi: 10.1007/978-3-030-16481-2_5)
2018
Rossitto, G., Touyz, R. M. , Petrie, M. C. and Delles, C. (2018) Much Ado about N...atrium: modelling tissuesodium as a highly sensitive marker of subclinicaland localized oedema. Clinical Science, 132(24), pp. 2609-2613. (doi: 10.1042/CS20180575) (PMID:30545897) (PMCID:PMC6365627)
Rossitto, G. and Touyz, R. (2018) Dr Giacomo Rossitto interviews Professor Rhian Touyz, on the translational applications of vascular smooth muscle cell biology in cardiovascular disease. [Audio]
Rossitto, G., Battistel, M., Barbiero, G., Bisogni, V., Maiolino, G., Diego, M., Seccia, T. M. and Rossi, G. P. (2018) The subtyping of primary aldosteronism by adrenal vein sampling: sequential blood sampling causes factitious lateralization. Journal of Hypertension, 36(2), pp. 335-343. (doi: 10.1097/HJH.0000000000001564) (PMID:28957852)
Articles
Rossi, G. P., Bagordo, D., Rossi, F. B., Pintus, G., Rossitto, G. and Seccia, T. M. (2024) ‘Essential’ arterial hypertension: time for a paradigm change. Journal of Hypertension, 42(8), pp. 1298-1304. (doi: 10.1097/hjh.0000000000003767) (PMID:38748508) (PMCID:PMC11216381)
Rossitto, G., Bertoldi, G., Rutkowski, J. M., Mitchell, B. M. and Delles, C. (2024) Sodium, interstitium, lymphatics, and hypertension - A tale of hydraulics. Hypertension, 81(4), pp. 727-737. (doi: 10.1161/HYPERTENSIONAHA.123.17942) (PMID:38385255)
Bagordo, D., Rossi, G. P., Delles, C. , Wiig, H. and Rossitto, G. (2023) The tangram of sodium and fluid balance: salt series. Hypertension, (doi: 10.1161/HYPERTENSIONAHA.123.19569) (Early Online Publication)
Zhu, R., Shagjaa, T., Rossitto, G., Caroccia, B., Seccia, T. M., Gregori, D. and Rossi, G. P. (2023) Exclusion tests in unilateral primary aldosteronism (ExcluPA) study. Journal of Clinical Endocrinology and Metabolism, 108(2), pp. 496-506. (doi: 10.1210/clinem/dgac654) (PMID:36373399)
Chen, J. Y., Chew, K. S., Mary, S. , Boder, P., Bagordo, D., Rossi, G. P., Touyz, R. M. , Delles, C. and Rossitto, G. (2022) Skin-specific mechanisms of body fluid regulation in hypertension. Clinical Science, 137(3), pp. 239-250. (doi: 10.1042/CS20220609) (PMID:36648486)
Rossitto, G. and Delles, C. (2022) Mechanisms of sodium-mediated injury in cardiovascular disease: old play, new scripts. FEBS Journal, 289(23), pp. 7260-7273. (doi: 10.1111/febs.16155) (PMID:34355504)
Rossi, G. P. and Rossitto, G. (2022) Aldosterone and cardiovascular damage: a new lesson from an old study. Hypertension, 79(9), pp. 1994-1996. (doi: 10.1161/hypertensionaha.122.19662) (PMID:35947644)
Sanga, V., Rossitto, G., Seccia, T. M. and Rossi, G. P. (2022) Management and outcomes of primary aldosteronism in pregnancy: a systematic review. Hypertension, 79(9), pp. 1912-1921. (doi: 10.1161/HYPERTENSIONAHA.121.18858) (PMID:35686552)
Rossitto, G. and Delles, C. (2022) Does excess tissue sodium storage regulate blood pressure? Current Hypertension Reports, 24(5), pp. 115-122. (doi: 10.1007/s11906-022-01180-x) (PMID:35192140) (PMCID:PMC9142429)
Rossi, G. P. et al. (2022) Drug-resistant hypertension in primary aldosteronism patients undergoing adrenal vein sampling: the AVIS-2-RH study. European Journal of Preventive Cardiology, 29(2), e85-e93. (doi: 10.1093/eurjpc/zwaa108) (PMID:33742213)
Delles, C. and Rossitto, G. (2022) Of snails, earthworms, and men: insights into strategies to preserve water. Function, 3(1), zqab071. (doi: 10.1093/function/zqab071) (PMID:35330922) (PMCID:PMC8788808)
Mary, S. , Boder, P., Rossitto, G., Graham, L. , Scott, K., Flynn, A., Kipgen, D., Graham, D. and Delles, C. (2021) Salt loading decreases urinary excretion and increases intracellular accumulation of uromodulin in stroke-prone spontaneously hypertensive rats. Clinical Science, 135(24), pp. 2749-2761. (doi: 10.1042/CS20211017) (PMID:34870708) (PMCID:PMC8689196)
Rossi, G. P. et al. (2021) Feasibility of imaging-guided adrenalectomy in young patients with primary aldosteronism. Hypertension, 79(1), pp. 187-195. (doi: 10.1161/HYPERTENSIONAHA.121.18284) (PMID:34878892)
Murray, E. , Rossitto, G. and Delles, C. (2021) Haemodynamic assessment in hypertension: the soloists and the orchestra. Journal of Hypertension, 39(6), pp. 1109-1111. (doi: 10.1097/HJH.0000000000002796) (PMID:33967215)
Rossitto, G. et al. (2021) High sodium intake, glomerular hyperfiltration and protein catabolism in patients with essential hypertension. Cardiovascular Research, 117(5), pp. 1372-1381. (doi: 10.1093/cvr/cvaa205) (PMID:33053160) (PMCID:PMC8064429)
Rossitto, G. et al. (2020) Reduced lymphatic reserve in heart failure with preserved ejection fraction. Journal of the American College of Cardiology, 76(24), pp. 2817-2829. (doi: 10.1016/j.jacc.2020.10.022) (PMID:33303070) (PMCID:PMC7724570)
Rossitto, G. et al. (2020) Tissue sodium excess is not hypertonic and reflects extracellular volume expansion. Nature Communications, 11, 4222. (doi: 10.1038/s41467-020-17820-2) (PMID:32839436) (PMCID:PMC7445299)
Rossitto, G. et al. (2020) Subtyping of primary aldosteronism in the AVIS-2 study: assessment of selectivity and lateralization. Journal of Clinical Endocrinology and Metabolism, 105(6), pp. 2042-2052. (doi: 10.1210/clinem/dgz017) (PMID:31536622)
Rossi, G. P. et al. (2019) Clinical outcomes of 1625 patients with primary aldosteronism subtyped with adrenal vein sampling. Hypertension, 74(4), pp. 800-808. (doi: 10.1161/HYPERTENSIONAHA.119.13463) (PMID:31476901)
Rossitto, G., Touyz, R. M. , Petrie, M. C. and Delles, C. (2018) Much Ado about N...atrium: modelling tissuesodium as a highly sensitive marker of subclinicaland localized oedema. Clinical Science, 132(24), pp. 2609-2613. (doi: 10.1042/CS20180575) (PMID:30545897) (PMCID:PMC6365627)
Rossitto, G., Battistel, M., Barbiero, G., Bisogni, V., Maiolino, G., Diego, M., Seccia, T. M. and Rossi, G. P. (2018) The subtyping of primary aldosteronism by adrenal vein sampling: sequential blood sampling causes factitious lateralization. Journal of Hypertension, 36(2), pp. 335-343. (doi: 10.1097/HJH.0000000000001564) (PMID:28957852)
Book Sections
Mary, S. , Rossitto, G. and Delles, C. (2022) Pathophysiology of hypertension. In: Nadar, Sunil and Lip, Gregory (eds.) Hypertension. Series: Oxford cardiology library. Oxford University Press: Oxford, pp. 11-20. ISBN 9780198870678 (doi: 10.1093/med/9780198870678.003.0002)
Cameron, A. C., Rossitto, G., Lang, N. N. and Touyz, R. M. (2019) Antihypertensive drugs and vascular health. In: Zimlichman, Reuven, Julius, Stevo and Mancia, Giuseppe (eds.) Prehypertension and Cardiometabolic Syndrome. Series: Updates in hypertension and cardiovascular protection. Springer, pp. 585-605. ISBN 9783319753096 (doi: 10.1007/978-3-319-75310-2_37)
Rossitto, G., Sneddon, M. and Rockson, S. G. (2019) The lymphatic system. In: Touyz, Rhian M. and Delles, Christian (eds.) Textbook of Vascular Medicine. Springer: Cham, pp. 45-57. ISBN 9783030164805 (doi: 10.1007/978-3-030-16481-2_5)
Audio
Rossitto, G. and Touyz, R. (2018) Dr Giacomo Rossitto interviews Professor Rhian Touyz, on the translational applications of vascular smooth muscle cell biology in cardiovascular disease. [Audio]