2023

Kuo, C.-W. S. et al. (2023) Palmitoylation of the pore-forming subunit of Ca(v)1.2 controls channel voltage sensitivity and calcium transients in cardiac myocytes. Proceedings of the National Academy of Sciences of the United States of America, 120(7), e220788712. (doi: 10.1073/pnas.2207887120) (PMID:36745790) (PMCID:PMC9963536)

2022

Lachaud, Q., Aziz, M. H. N., Burton, F. L., Macquaide, N. , Myles, R. C. , Simitev, R. D. and Smith, G. L. (2022) Electrophysiological heterogeneity in large populations of rabbit ventricular cardiomyocytes. Cardiovascular Research, 118(15), pp. 3112-3125. (doi: 10.1093/cvr/cvab375) (PMID:35020837) (PMCID:PMC9732512)

Fertig, B. et al. (2022) SUMOylation does not affect cardiac troponin I stability but alters indirectly the development of force in response to Ca2+. FEBS Journal, 289(20), pp. 6267-6285. (doi: 10.1111/febs.16537) (PMID:35633070) (PMCID:PMC9588612)

Tibbo, A. J. et al. (2022) Phosphodiesterase type 4 anchoring regulates cAMP signaling to Popeye domain-containing proteins. Journal of Molecular and Cellular Cardiology, 165, pp. 86-102. (doi: 10.1016/j.yjmcc.2022.01.001) (PMID:34999055) (PMCID:PMC8986152)

2019

Chakraborty, A.D., Gonano, L.A., Munro, M.L., Smith, L.J., Thekkedam, C., Staudacher, V., Gamble, A.B., Macquaide, N. , Dulhunty, A.F. and Jones, P.P. (2019) Activation of RyR2 by class I kinase inhibitors. British Journal of Pharmacology, 176(6), pp. 773-786. (doi: 10.1111/bph.14562) (PMID:30588601)

Shen, X. et al. (2019) 3D dSTORM imaging reveals novel detail of ryanodine receptor localization in rat cardiac myocytes. Journal of Physiology, 597(2), pp. 399-418. (doi: 10.1113/jp277360) (PMID:30412283) (PMCID:PMC6332759)

2018

Jones, P. P., MacQuaide, N. and Louch, W. E. (2018) Dyadic plasticity in cardiomyocytes. Frontiers in Physiology, 9, 1773. (doi: 10.3389/fphys.2018.01773) (PMID:30618792) (PMCID:PMC6298195)

Henry, A. D., MacQuaide, N. , Burton, F.L., Rankin, A.C., Rowan, E.G. and Drummond, R.M. (2018) Spontaneous Ca2+ transients in rat pulmonary vein cardiomyocytes are increased in frequency and become more synchronous following electrical stimulation. Cell calcium, 76, pp. 36-47. (doi: 10.1016/j.ceca.2018.09.001) (PMID:30253263)

Kolstad, T. R. et al. (2018) Ryanodine receptor dispersion disrupts Ca2+ release in failing cardiac myocytes. eLife, 7, pp. 1-24. e39427. (doi: 10.7554/eLife.39427) (PMID:30375974) (PMCID:PMC6245731)

Dries, E. et al. (2018) Hyperactive ryanodine receptors in human heart failure and ischemic cardiomyopathy reside outside of couplons. Cardiovascular Research, 114(11), pp. 1512-1524. (doi: 10.1093/cvr/cvy088) (PMID:29668881) (PMCID:PMC6106102)

Boyd, D., Workman, A. and MacQuaide, N. (2018) Super resolution imaging of ryanodine receptor cluster morphology in rabbit and human atrial myocytes. Biophysical Journal, 114(3 Sup1), 621a. (doi: 10.1016/j.bpj.2017.11.3358)

Lachaud, Q., MacQuaide, N. , Burton, F. and Smith, G. (2018) High-throughput study of rabbit ventricle action potential populations in MI model. Biophysical Journal, 114(3.S1), 625A. (doi: 10.1016/j.bpj.2017.11.3377)

Saxena, P., Smith, G. and MacQuaide, N. (2018) Early diastolic Ca 2+ sparks alter repolarization rate of rabbit cardiomyocytes. Biophysical Journal, 114(3.S1), 288A. (doi: 10.1016/j.bpj.2017.11.1653)

2015

MacQuaide, N. , Tuan, H.-T. M., Hotta, J.-I., Sempels, W., Lenaerts, I., Holemans, P., Hofkens, J., Jafri, M. S., Willems, R. and Sipido, K. R. (2015) Ryanodine receptor cluster fragmentation and redistribution in persistent atrial fibrillation enhance calcium release. Cardiovascular Research, 108(3), pp. 387-398. (doi: 10.1093/cvr/cvv231) (PMID:26490742) (PMCID:PMC4648199)

Sipido, K. R., MacQuaide, N. and Bito, V. (2015) A systematic approach for assessing Ca²⁺ handling in cardiac myocytes. Cold Spring Harbor Protocols, 2015(5), pp. 431-433. (doi: 10.1101/pdb.top066142) (PMID:25934941)

Bito, V., Sipido, K. R. and MacQuaide, N. (2015) Assessing Ca²⁺-removal pathways in cardiac myocytes. Cold Spring Harbor Protocols, 2015(5), pp. 498-503. (doi: 10.1101/pdb.prot076992) (PMID:25934931)

MacQuaide, N. , Bito, V. and Sipido, K. R. (2015) Measuring Ca²⁺ sparks in cardiac myocytes. Cold Spring Harbor Protocols, 2015(5), pp. 490-7. (doi: 10.1101/pdb.prot076984) (PMID:25934930)

Smith, G. L. and MacQuaide, N. (2015) The direct actions of flecainide on the human cardiac ryanodine receptor: keeping open the debate on the mechanism of action of local anesthetics in CPVT. Circulation Research, 116(8), pp. 1284-1286. (doi: 10.1161/CIRCRESAHA.115.306298) (PMID:25858058)

Bito, V., MacQuaide, N. and Sipido, K. R. (2015) Characterizing the trigger for sarcoplasmic reticulum Ca2+ release in cardiac myocytes. Cold Spring Harbor Protocols, 2015(4), pp. 398-402. (doi: 10.1101/pdb.prot076968) (PMID:25834258)

Bito, V., Sipido, K. R. and MacQuaide, N. (2015) Basic methods for monitoring intracellular Ca2+ in cardiac myocytes using Fluo-3. Cold Spring Harbor Protocols, 2015(4), pp. 392-397. (doi: 10.1101/pdb.prot076950) (PMID:25834257)

Macquaide, N. , Bito, V. and Sipido, K. R. (2015) Measuring sarcoplasmic reticulum Ca2+ content, fractional release, and Ca2+ buffering in cardiac myocytes. Cold Spring Harbor Protocols, 2015(4), pdb.prot07. (doi: 10.1101/pdb.prot076976)

2014

Dries, E., Lenaerts, I., MacQuaide, N. , Santiago, D., Claus, P. and Sipido, K.R. (2014) 53 * altered CaMKII and ROS microdomains favor sparks in orphaned RyR after myocardial infarction. Cardiovascular Research, 103, S1. (doi: 10.1093/cvr/cvu081.1)

Dries, E., Lenaerts, I., MacQuaide, N. , Santiago, D., Claus, P. and Sipido, K. R. (2014) Altered CamkII and Ros microdomains favor sparks in orphaned RyR after myocardial infarction. Biophysical Journal, 106(2), 322a. (doi: 10.1016/j.bpj.2013.11.1856)

MacQuaide, N. et al. (2014) Structural and functional alteration of RyR clusters after remodeling in persistent atrial fibrillation. Biophysical Journal, 106(2.S1), 431A. (doi: 10.1016/j.bpj.2013.11.2428)

2013

Dries, E., Bito, V., Lenaerts, I., Antoons, G., Sipido, K. R. and MacQuaide, N. (2013) Selective modulation of coupled ryanodine receptors during microdomain activation of calcium/calmodulin-dependent kinase ii in the dyadic cleft. Circulation Research, 113(11), pp. 1242-1252. (doi: 10.1161/CIRCRESAHA.113.301896) (PMID:24081880)

Hohendanner, F. et al. (2013) Intracellular dyssynchrony of diastolic cytosolic [Ca2+] decay in ventricular cardiomyocytes in cardiac remodeling and human heart failure. Circulation Research, 113(5), pp. 527-538. (doi: 10.1161/CIRCRESAHA.113.300895) (PMID:23825358)

2012

Sipido, K. R., Acsai, K., Antoons, G., Bito, V. and MacQuaide, N. (2012) T-tubule remodelling and ryanodine receptor organization modulate sodium-calcium exchange. In: Sodium Calcium Exchange: A Growing Spectrum of Pathophysiological Implications. Series: Advances in Experimental Medicine and Biology (961). Springer: Boston, MA, pp. 375-383. ISBN 978-1-4614-4755-9 (doi: 10.1007/978-1-4614-4756-6_32)

Sipido, K. R., Acsai, K., Antoons, G., Bito, V. and MacQuaide, N. (2012) T-tubule remodelling and ryanodine receptor organization modulate sodium-calcium exchange. Advances in Experimental Medicine and Biology, 961, pp. 375-83. (doi: 10.1007/978-1-4614-4756-6_32) (PMID:23224896)

Dries, E., Bito, V., Sipido, K. and MacQuaide, N. (2012) 3-D localization of subcellular Ca2+ release reveals a cytoskeletal dependence of RyR activation. Biophysical Journal, 102(3), S1. (doi: 10.1016/j.bpj.2011.11.1736)

Kemi, O. J. , MacQuaide, N. , Hoydal, M. A., Ellingsen, O., Smith, G. L. and Wisloff, U. (2012) Exercise training corrects control of spontaneous calcium waves in hearts from myocardial infarction heart failure rats. Journal of Cellular Physiology, 227(1), pp. 20-26. (doi: 10.1002/jcp.22771)

Bito, V., Biesmans, L., Gellen, B., Antoons, G., MacQuaide, N. , Rouet-Benzineb, P., Pezet, M., Mercadier, J.-J. and Sipido, K. R. (2012) FKBP12.6 overexpression does not protect against remodelling after myocardial infarction. Experimental Physiology, 98(1), pp. 134-48. (doi: 10.1113/expphysiol.2011.064089) (PMID:22689442)

Heinzel, F. R., Hohendanner, F., MacQuaide, N. , Antoon, G., Sipido, K. and Pieske, B. (2012) Intracellular dyssynchrony in calcium removal in ventricular cardiac myocytes. Biophysical Journal, 102(3.S1), 552A. (doi: 10.1016/j.bpj.2011.11.3011)

MacQuaide, N. , Hotta, J.-i., Tuan, H.-T., Williams, G. S.B., Willems, R., Jafri, S., Hofkens, J. and Sipido, K. R. (2012) Variable RyR cluster morphology in sheep atrial myocytes : super resolution measurement and Ca2+ release simulation. Biophysical Journal, 102(3.S1), 309A. (doi: 10.1016/j.bpj.2011.11.1705)

2011

Kemi, O. J. , Hoydal, M. A., MacQuaide, N. , Haram, P. M., Koch, L. G., Britton, S. L., Ellingsen, O., Smith, G. L. and Wisloff, U. (2011) The effect of exercise training on transverse tubules in normal, remodeled, and reverse remodeled hearts. Journal of Cellular Physiology, 226(9), pp. 2235-2243. (doi: 10.1002/jcp.22559)

Heinzel, F. R., MacQuaide, N. , Biesmans, L. and Sipido, K. (2011) Dyssynchrony of Ca2+ release from the sarcoplasmic reticulum as subcellular mechanism of cardiac contractile dysfunction. Journal of Molecular and Cellular Cardiology, 50(3), pp. 390-400. (doi: 10.1016/j.yjmcc.2010.11.008) (PMID:21075114)

MacQuaide, N. and Sipido, K. R. (2011) Blink and you'll see it: how to detect Ca2+ quarks. Circulation Research, 108(2), pp. 154-156. (doi: 10.1161/CIRCRESAHA.110.238766) (PMID:21252146)

Rota, M., Biesmans, L., MacQuaide, N. , Heinzel, F.R., Bito, V., Smith, G.L. and Sipido, K.R. (2011) Subcellular heterogeneity of ryanodine receptor properties in ventricular myocytes with low T-tubule density. PLoS ONE, 6(10), e25100. (doi: 10.1371/journal.pone.0025100)

2010

MacQuaide, N. , Ramay, H.R., Sobie, E.A. and Smith, G.L. (2010) Differential sensitivity of Ca2+ wave and Ca2+ spark events to ruthenium red in isolated permeabilised rabbit cardiomyocytes. Journal of Physiology, 588(23), pp. 4731-4742. (doi: 10.1113/jphysiol.2010.193375)

Zamparelli, C., MacQuaide, N. , Colotti, G., Verzili, D., Seidler, T., Smith, G. L. and Chiancone, E. (2010) Activation of the cardiac Na+–Ca2+ exchanger by sorcin via the interaction of the respective Ca2+-binding domains. Journal of Molecular and Cellular Cardiology, 49(1), pp. 132-141. (doi: 10.1016/j.yjmcc.2010.03.003) (PMID:20298697) (PMCID:PMC2958309)

2009

MacQuaide, N. , Dempster, J. and Smith, G. L. (2009) Assessment of sarcoplasmic reticulum Ca2+ depletion during spontaneous Ca2+ waves in isolated permeabilized rabbit ventricular cardiomyocytes. Biophysical Journal, 96(7), pp. 2744-2754. (doi: 10.1016/j.bpj.2008.12.3944) (PMID:19348757) (PMCID:PMC2711300)

Kemi, O. , MacQuaide, N. , Hoydal, M.A., Haram, P.M., Ellingsen, O., Wisloff, U. and Smith, G. (2009) Exercise training reduces spontaneous Ca2+ waves in cardiomyocytes from post-myocardial infarction heart failure rats. Biophysical Journal, 96(3.S1), 274A-275A. (doi: 10.1016/j.bpj.2008.12.1359)

Kemi, O., MacQuaide, N. , Hoydal, M. A., Haram, P. M., Ellingsen, O., Smith, G. L. and Wisloff, U. (2009) Exercise training corrects control of diastolic calcium in hearts from myocardial infarction heart failure rats. Medicine & Science in Sports & Exercise, 41(5), p. 174. (doi: 10.1249/01.mss.0000355086.27397.a8)

MacQuaide, N. , Anthony, D. F., Currie, S. and Smith, G. L. (2009) Upregulation Of Cam Kinase IIδ modulates ppontaneous Ca2+ wave properties in a rabbit model of heart failure. Biophysical Journal, 96(3.S1), 275A. (doi: 10.1016/j.bpj.2008.12.1360)

Reynolds, M., MacQuaide, N. , Thomas, M. and Smith, G. (2009) UV ratiometric imaging of isolated ventricular cardiomyocytes using an LED based illuminator. Biophysical Journal, 96(3.S1), 638A. (doi: 10.1016/j.bpj.2008.12.3373)

2008

Smith, G. and MacQuaide, N. (2008) Cytoplasmic versus intra-SR: the battle of the Ca2+ diffusion coefficients in cardiac muscle. Biophysical Journal, 95(3), pp. 1005-1006. (doi: 10.1529/biophysj.108.133926) (PMID:18469088) (PMCID:PMC2479579)

Adamson, M., MacQuaide, N. , Helgerud, J., Hoff, J. and Kemi, O.J. (2008) Unilateral arm strength training improves contralateral peak force and rate of force development. European Journal of Applied Physiology, 103(5), pp. 553-559. (doi: 10.1007/s00421-008-0750-6) (PMID:18443814)

2007

MacQuaide, N. , Dempster, J. and Smith, G.L. (2007) Measurement and modeling of Ca2+ waves in isolated rabbit ventricular cardiomyocytes. Biophysical Journal, 93(7), pp. 2581-2595. (doi: 10.1529/biophysj.106.102293) (PMID:17545234) (PMCID:PMC1965444)

Volkers, M. et al. (2007) S100A1 decreases calcium spark frequency and alters their spatial characteristics in permeabilized adult ventricular cardiomyocytes. Cell Calcium, 41(2), pp. 135-143. (doi: 10.1016/j.ceca.2006.06.001) (PMID:16919727)

Kemi, O. J., MacQuaide, N. , Hoydal, M., Haram, P. M., Ellingsen, O., Smith, G. L. and Wisloff, U. (2007) Physiologic, but not pathologic hypertrophy of the cardiomyocyte sustains transverse tubule density. Medicine & Science in Sports & Exercise, 39(5), S97. (doi: 10.1249/01.mss.0000273297.89780.30)

2006

Smith, G. and MacQuaide, N. (2006) Swallowing a spider to catch a fly: ca-calmodulin dynamics in adult cardiomyocytes. Journal of Molecular and Cellular Cardiology, 41(3), pp. 416-417. (doi: 10.1016/j.yjmcc.2006.06.008) (PMID:16870208)

2003

Zhang, H. et al. (2003) Dynamics of cardiac intracellular Ca2+ handling - from experiments to virtual cells. International Journal of Bifurcation and Chaos, 13(12), pp. 3535-3560. (doi: 10.1142/S0218127403008843)

Articles

Kuo, C.-W. S. et al. (2023) Palmitoylation of the pore-forming subunit of Ca(v)1.2 controls channel voltage sensitivity and calcium transients in cardiac myocytes. Proceedings of the National Academy of Sciences of the United States of America, 120(7), e220788712. (doi: 10.1073/pnas.2207887120) (PMID:36745790) (PMCID:PMC9963536)

Lachaud, Q., Aziz, M. H. N., Burton, F. L., Macquaide, N. , Myles, R. C. , Simitev, R. D. and Smith, G. L. (2022) Electrophysiological heterogeneity in large populations of rabbit ventricular cardiomyocytes. Cardiovascular Research, 118(15), pp. 3112-3125. (doi: 10.1093/cvr/cvab375) (PMID:35020837) (PMCID:PMC9732512)

Fertig, B. et al. (2022) SUMOylation does not affect cardiac troponin I stability but alters indirectly the development of force in response to Ca2+. FEBS Journal, 289(20), pp. 6267-6285. (doi: 10.1111/febs.16537) (PMID:35633070) (PMCID:PMC9588612)

Tibbo, A. J. et al. (2022) Phosphodiesterase type 4 anchoring regulates cAMP signaling to Popeye domain-containing proteins. Journal of Molecular and Cellular Cardiology, 165, pp. 86-102. (doi: 10.1016/j.yjmcc.2022.01.001) (PMID:34999055) (PMCID:PMC8986152)

Chakraborty, A.D., Gonano, L.A., Munro, M.L., Smith, L.J., Thekkedam, C., Staudacher, V., Gamble, A.B., Macquaide, N. , Dulhunty, A.F. and Jones, P.P. (2019) Activation of RyR2 by class I kinase inhibitors. British Journal of Pharmacology, 176(6), pp. 773-786. (doi: 10.1111/bph.14562) (PMID:30588601)

Shen, X. et al. (2019) 3D dSTORM imaging reveals novel detail of ryanodine receptor localization in rat cardiac myocytes. Journal of Physiology, 597(2), pp. 399-418. (doi: 10.1113/jp277360) (PMID:30412283) (PMCID:PMC6332759)

Jones, P. P., MacQuaide, N. and Louch, W. E. (2018) Dyadic plasticity in cardiomyocytes. Frontiers in Physiology, 9, 1773. (doi: 10.3389/fphys.2018.01773) (PMID:30618792) (PMCID:PMC6298195)

Henry, A. D., MacQuaide, N. , Burton, F.L., Rankin, A.C., Rowan, E.G. and Drummond, R.M. (2018) Spontaneous Ca2+ transients in rat pulmonary vein cardiomyocytes are increased in frequency and become more synchronous following electrical stimulation. Cell calcium, 76, pp. 36-47. (doi: 10.1016/j.ceca.2018.09.001) (PMID:30253263)

Kolstad, T. R. et al. (2018) Ryanodine receptor dispersion disrupts Ca2+ release in failing cardiac myocytes. eLife, 7, pp. 1-24. e39427. (doi: 10.7554/eLife.39427) (PMID:30375974) (PMCID:PMC6245731)

Dries, E. et al. (2018) Hyperactive ryanodine receptors in human heart failure and ischemic cardiomyopathy reside outside of couplons. Cardiovascular Research, 114(11), pp. 1512-1524. (doi: 10.1093/cvr/cvy088) (PMID:29668881) (PMCID:PMC6106102)

Boyd, D., Workman, A. and MacQuaide, N. (2018) Super resolution imaging of ryanodine receptor cluster morphology in rabbit and human atrial myocytes. Biophysical Journal, 114(3 Sup1), 621a. (doi: 10.1016/j.bpj.2017.11.3358)

Lachaud, Q., MacQuaide, N. , Burton, F. and Smith, G. (2018) High-throughput study of rabbit ventricle action potential populations in MI model. Biophysical Journal, 114(3.S1), 625A. (doi: 10.1016/j.bpj.2017.11.3377)

Saxena, P., Smith, G. and MacQuaide, N. (2018) Early diastolic Ca 2+ sparks alter repolarization rate of rabbit cardiomyocytes. Biophysical Journal, 114(3.S1), 288A. (doi: 10.1016/j.bpj.2017.11.1653)

MacQuaide, N. , Tuan, H.-T. M., Hotta, J.-I., Sempels, W., Lenaerts, I., Holemans, P., Hofkens, J., Jafri, M. S., Willems, R. and Sipido, K. R. (2015) Ryanodine receptor cluster fragmentation and redistribution in persistent atrial fibrillation enhance calcium release. Cardiovascular Research, 108(3), pp. 387-398. (doi: 10.1093/cvr/cvv231) (PMID:26490742) (PMCID:PMC4648199)

Sipido, K. R., MacQuaide, N. and Bito, V. (2015) A systematic approach for assessing Ca²⁺ handling in cardiac myocytes. Cold Spring Harbor Protocols, 2015(5), pp. 431-433. (doi: 10.1101/pdb.top066142) (PMID:25934941)

Bito, V., Sipido, K. R. and MacQuaide, N. (2015) Assessing Ca²⁺-removal pathways in cardiac myocytes. Cold Spring Harbor Protocols, 2015(5), pp. 498-503. (doi: 10.1101/pdb.prot076992) (PMID:25934931)

MacQuaide, N. , Bito, V. and Sipido, K. R. (2015) Measuring Ca²⁺ sparks in cardiac myocytes. Cold Spring Harbor Protocols, 2015(5), pp. 490-7. (doi: 10.1101/pdb.prot076984) (PMID:25934930)

Smith, G. L. and MacQuaide, N. (2015) The direct actions of flecainide on the human cardiac ryanodine receptor: keeping open the debate on the mechanism of action of local anesthetics in CPVT. Circulation Research, 116(8), pp. 1284-1286. (doi: 10.1161/CIRCRESAHA.115.306298) (PMID:25858058)

Bito, V., MacQuaide, N. and Sipido, K. R. (2015) Characterizing the trigger for sarcoplasmic reticulum Ca2+ release in cardiac myocytes. Cold Spring Harbor Protocols, 2015(4), pp. 398-402. (doi: 10.1101/pdb.prot076968) (PMID:25834258)

Bito, V., Sipido, K. R. and MacQuaide, N. (2015) Basic methods for monitoring intracellular Ca2+ in cardiac myocytes using Fluo-3. Cold Spring Harbor Protocols, 2015(4), pp. 392-397. (doi: 10.1101/pdb.prot076950) (PMID:25834257)

Macquaide, N. , Bito, V. and Sipido, K. R. (2015) Measuring sarcoplasmic reticulum Ca2+ content, fractional release, and Ca2+ buffering in cardiac myocytes. Cold Spring Harbor Protocols, 2015(4), pdb.prot07. (doi: 10.1101/pdb.prot076976)

Dries, E., Lenaerts, I., MacQuaide, N. , Santiago, D., Claus, P. and Sipido, K.R. (2014) 53 * altered CaMKII and ROS microdomains favor sparks in orphaned RyR after myocardial infarction. Cardiovascular Research, 103, S1. (doi: 10.1093/cvr/cvu081.1)

Dries, E., Lenaerts, I., MacQuaide, N. , Santiago, D., Claus, P. and Sipido, K. R. (2014) Altered CamkII and Ros microdomains favor sparks in orphaned RyR after myocardial infarction. Biophysical Journal, 106(2), 322a. (doi: 10.1016/j.bpj.2013.11.1856)

MacQuaide, N. et al. (2014) Structural and functional alteration of RyR clusters after remodeling in persistent atrial fibrillation. Biophysical Journal, 106(2.S1), 431A. (doi: 10.1016/j.bpj.2013.11.2428)

Dries, E., Bito, V., Lenaerts, I., Antoons, G., Sipido, K. R. and MacQuaide, N. (2013) Selective modulation of coupled ryanodine receptors during microdomain activation of calcium/calmodulin-dependent kinase ii in the dyadic cleft. Circulation Research, 113(11), pp. 1242-1252. (doi: 10.1161/CIRCRESAHA.113.301896) (PMID:24081880)

Hohendanner, F. et al. (2013) Intracellular dyssynchrony of diastolic cytosolic [Ca2+] decay in ventricular cardiomyocytes in cardiac remodeling and human heart failure. Circulation Research, 113(5), pp. 527-538. (doi: 10.1161/CIRCRESAHA.113.300895) (PMID:23825358)

Sipido, K. R., Acsai, K., Antoons, G., Bito, V. and MacQuaide, N. (2012) T-tubule remodelling and ryanodine receptor organization modulate sodium-calcium exchange. Advances in Experimental Medicine and Biology, 961, pp. 375-83. (doi: 10.1007/978-1-4614-4756-6_32) (PMID:23224896)

Dries, E., Bito, V., Sipido, K. and MacQuaide, N. (2012) 3-D localization of subcellular Ca2+ release reveals a cytoskeletal dependence of RyR activation. Biophysical Journal, 102(3), S1. (doi: 10.1016/j.bpj.2011.11.1736)

Kemi, O. J. , MacQuaide, N. , Hoydal, M. A., Ellingsen, O., Smith, G. L. and Wisloff, U. (2012) Exercise training corrects control of spontaneous calcium waves in hearts from myocardial infarction heart failure rats. Journal of Cellular Physiology, 227(1), pp. 20-26. (doi: 10.1002/jcp.22771)

Bito, V., Biesmans, L., Gellen, B., Antoons, G., MacQuaide, N. , Rouet-Benzineb, P., Pezet, M., Mercadier, J.-J. and Sipido, K. R. (2012) FKBP12.6 overexpression does not protect against remodelling after myocardial infarction. Experimental Physiology, 98(1), pp. 134-48. (doi: 10.1113/expphysiol.2011.064089) (PMID:22689442)

Heinzel, F. R., Hohendanner, F., MacQuaide, N. , Antoon, G., Sipido, K. and Pieske, B. (2012) Intracellular dyssynchrony in calcium removal in ventricular cardiac myocytes. Biophysical Journal, 102(3.S1), 552A. (doi: 10.1016/j.bpj.2011.11.3011)

MacQuaide, N. , Hotta, J.-i., Tuan, H.-T., Williams, G. S.B., Willems, R., Jafri, S., Hofkens, J. and Sipido, K. R. (2012) Variable RyR cluster morphology in sheep atrial myocytes : super resolution measurement and Ca2+ release simulation. Biophysical Journal, 102(3.S1), 309A. (doi: 10.1016/j.bpj.2011.11.1705)

Kemi, O. J. , Hoydal, M. A., MacQuaide, N. , Haram, P. M., Koch, L. G., Britton, S. L., Ellingsen, O., Smith, G. L. and Wisloff, U. (2011) The effect of exercise training on transverse tubules in normal, remodeled, and reverse remodeled hearts. Journal of Cellular Physiology, 226(9), pp. 2235-2243. (doi: 10.1002/jcp.22559)

Heinzel, F. R., MacQuaide, N. , Biesmans, L. and Sipido, K. (2011) Dyssynchrony of Ca2+ release from the sarcoplasmic reticulum as subcellular mechanism of cardiac contractile dysfunction. Journal of Molecular and Cellular Cardiology, 50(3), pp. 390-400. (doi: 10.1016/j.yjmcc.2010.11.008) (PMID:21075114)

MacQuaide, N. and Sipido, K. R. (2011) Blink and you'll see it: how to detect Ca2+ quarks. Circulation Research, 108(2), pp. 154-156. (doi: 10.1161/CIRCRESAHA.110.238766) (PMID:21252146)

Rota, M., Biesmans, L., MacQuaide, N. , Heinzel, F.R., Bito, V., Smith, G.L. and Sipido, K.R. (2011) Subcellular heterogeneity of ryanodine receptor properties in ventricular myocytes with low T-tubule density. PLoS ONE, 6(10), e25100. (doi: 10.1371/journal.pone.0025100)

MacQuaide, N. , Ramay, H.R., Sobie, E.A. and Smith, G.L. (2010) Differential sensitivity of Ca2+ wave and Ca2+ spark events to ruthenium red in isolated permeabilised rabbit cardiomyocytes. Journal of Physiology, 588(23), pp. 4731-4742. (doi: 10.1113/jphysiol.2010.193375)

Zamparelli, C., MacQuaide, N. , Colotti, G., Verzili, D., Seidler, T., Smith, G. L. and Chiancone, E. (2010) Activation of the cardiac Na+–Ca2+ exchanger by sorcin via the interaction of the respective Ca2+-binding domains. Journal of Molecular and Cellular Cardiology, 49(1), pp. 132-141. (doi: 10.1016/j.yjmcc.2010.03.003) (PMID:20298697) (PMCID:PMC2958309)

MacQuaide, N. , Dempster, J. and Smith, G. L. (2009) Assessment of sarcoplasmic reticulum Ca2+ depletion during spontaneous Ca2+ waves in isolated permeabilized rabbit ventricular cardiomyocytes. Biophysical Journal, 96(7), pp. 2744-2754. (doi: 10.1016/j.bpj.2008.12.3944) (PMID:19348757) (PMCID:PMC2711300)

Kemi, O. , MacQuaide, N. , Hoydal, M.A., Haram, P.M., Ellingsen, O., Wisloff, U. and Smith, G. (2009) Exercise training reduces spontaneous Ca2+ waves in cardiomyocytes from post-myocardial infarction heart failure rats. Biophysical Journal, 96(3.S1), 274A-275A. (doi: 10.1016/j.bpj.2008.12.1359)

Kemi, O., MacQuaide, N. , Hoydal, M. A., Haram, P. M., Ellingsen, O., Smith, G. L. and Wisloff, U. (2009) Exercise training corrects control of diastolic calcium in hearts from myocardial infarction heart failure rats. Medicine & Science in Sports & Exercise, 41(5), p. 174. (doi: 10.1249/01.mss.0000355086.27397.a8)

MacQuaide, N. , Anthony, D. F., Currie, S. and Smith, G. L. (2009) Upregulation Of Cam Kinase IIδ modulates ppontaneous Ca2+ wave properties in a rabbit model of heart failure. Biophysical Journal, 96(3.S1), 275A. (doi: 10.1016/j.bpj.2008.12.1360)

Reynolds, M., MacQuaide, N. , Thomas, M. and Smith, G. (2009) UV ratiometric imaging of isolated ventricular cardiomyocytes using an LED based illuminator. Biophysical Journal, 96(3.S1), 638A. (doi: 10.1016/j.bpj.2008.12.3373)

Smith, G. and MacQuaide, N. (2008) Cytoplasmic versus intra-SR: the battle of the Ca2+ diffusion coefficients in cardiac muscle. Biophysical Journal, 95(3), pp. 1005-1006. (doi: 10.1529/biophysj.108.133926) (PMID:18469088) (PMCID:PMC2479579)

Adamson, M., MacQuaide, N. , Helgerud, J., Hoff, J. and Kemi, O.J. (2008) Unilateral arm strength training improves contralateral peak force and rate of force development. European Journal of Applied Physiology, 103(5), pp. 553-559. (doi: 10.1007/s00421-008-0750-6) (PMID:18443814)

MacQuaide, N. , Dempster, J. and Smith, G.L. (2007) Measurement and modeling of Ca2+ waves in isolated rabbit ventricular cardiomyocytes. Biophysical Journal, 93(7), pp. 2581-2595. (doi: 10.1529/biophysj.106.102293) (PMID:17545234) (PMCID:PMC1965444)

Volkers, M. et al. (2007) S100A1 decreases calcium spark frequency and alters their spatial characteristics in permeabilized adult ventricular cardiomyocytes. Cell Calcium, 41(2), pp. 135-143. (doi: 10.1016/j.ceca.2006.06.001) (PMID:16919727)

Kemi, O. J., MacQuaide, N. , Hoydal, M., Haram, P. M., Ellingsen, O., Smith, G. L. and Wisloff, U. (2007) Physiologic, but not pathologic hypertrophy of the cardiomyocyte sustains transverse tubule density. Medicine & Science in Sports & Exercise, 39(5), S97. (doi: 10.1249/01.mss.0000273297.89780.30)

Smith, G. and MacQuaide, N. (2006) Swallowing a spider to catch a fly: ca-calmodulin dynamics in adult cardiomyocytes. Journal of Molecular and Cellular Cardiology, 41(3), pp. 416-417. (doi: 10.1016/j.yjmcc.2006.06.008) (PMID:16870208)

Zhang, H. et al. (2003) Dynamics of cardiac intracellular Ca2+ handling - from experiments to virtual cells. International Journal of Bifurcation and Chaos, 13(12), pp. 3535-3560. (doi: 10.1142/S0218127403008843)

Book Sections

Sipido, K. R., Acsai, K., Antoons, G., Bito, V. and MacQuaide, N. (2012) T-tubule remodelling and ryanodine receptor organization modulate sodium-calcium exchange. In: Sodium Calcium Exchange: A Growing Spectrum of Pathophysiological Implications. Series: Advances in Experimental Medicine and Biology (961). Springer: Boston, MA, pp. 375-383. ISBN 978-1-4614-4755-9 (doi: 10.1007/978-1-4614-4756-6_32)