Dr Hugh Elder
- Honorary Research Fellow (School of Cardiovascular & Metabolic Health)
email:
Hugh.Elder@glasgow.ac.uk
Publications
2020
McGuigan, J. A.S., Kay, J. W. and Elder, H. Y. (2020) Ionized concentrations in Ca2+ and Mg2+ buffers must be measured, not calculated. Experimental Physiology, 105(3), pp. 427-437. (doi: 10.1113/EP088345) (PMID:31758871)
2017
McGuigan, J. A.S., Kay, J. W. and Elder, H. Y. (2017) Ionised concentrations in calcium and magnesium buffers: standards and precise measurement are mandatory. Progress in Biophysics and Molecular Biology, 126, pp. 48-64. (doi: 10.1016/j.pbiomolbio.2017.03.001) (PMID:28450155)
2016
McGuigan, J.A.S., Kay, J.W. and Elder, H.Y. (2016) Why are the problems associated with the lack of international standards for Ca²⁺/Mg²⁺ buffers still being ignored? Physiology News, 103, 26 - 29.
2014
McGuigan, J. A.S., Kay, J. W. and Elder, H. Y. (2014) An improvement to the ligand optimisation method (LOM) for measuring the apparent dissociation constant and ligand purity in Ca²⁺ and Mg²⁺ buffer solutions. Progress in Biophysics and Molecular Biology, 116, 203 - 211. (doi: 10.1016/j.pbiomolbio.2014.04.001) (PMID:24836054)
2008
Kay, J.W. , Steven, R.J., McGuigan, J.A.S. and Elder, H. (2008) Automatic determination of ligand purity and apparent dissociation constant (Kapp) in Ca2+/Mg2+ buffer solutions and the Kapp for Ca2+/Mg2+ anion binding in physiological solutions from Ca2+/Mg2+-macroelectrode measurements. Computers in Biology and Medicine, 38(1), pp. 101-110. (doi: 10.1016/j.compbiomed.2007.07.008) (PMID:17854794)
2007
McGuigan, J., Kay, J.W. , Elder, H.Y. and Luthi, D. (2007) Comparison between measured and calculated ionised concentrations in Mg2+/ATP,Mg2+/EDTA and Ca2+/EGTA buffers;influence of changes in temperature, pH and pipetting errors on the ionised concentrations. Magnesium Research, 20(1), pp. 72-81. (doi: 10.1684/mrh.2007.0092) (PMID:17536492)
2006
McGuigan, J.A.S., Kay, J.W. and Elder, H.Y. (2006) Critical review of the methods used to measure the apparent dissociation constant and ligand purity in Ca2+ and Mg2+ buffer solutions. Progress in Biophysics and Molecular Biology, 92, pp. 333-370. (doi: 10.1016/j.pbiomolbio.2006.05.001) (PMID:16887174)
1990
Reid, C.A., Moss, V.A., Kay, J.W. and Elder, H.Y. (1990) Towards automatic segmentation and classification of mineralised bone. Transactions of the Royal Microscopical Society, pp. 543-546.
Articles
McGuigan, J. A.S., Kay, J. W. and Elder, H. Y. (2020) Ionized concentrations in Ca2+ and Mg2+ buffers must be measured, not calculated. Experimental Physiology, 105(3), pp. 427-437. (doi: 10.1113/EP088345) (PMID:31758871)
McGuigan, J. A.S., Kay, J. W. and Elder, H. Y. (2017) Ionised concentrations in calcium and magnesium buffers: standards and precise measurement are mandatory. Progress in Biophysics and Molecular Biology, 126, pp. 48-64. (doi: 10.1016/j.pbiomolbio.2017.03.001) (PMID:28450155)
McGuigan, J.A.S., Kay, J.W. and Elder, H.Y. (2016) Why are the problems associated with the lack of international standards for Ca²⁺/Mg²⁺ buffers still being ignored? Physiology News, 103, 26 - 29.
McGuigan, J. A.S., Kay, J. W. and Elder, H. Y. (2014) An improvement to the ligand optimisation method (LOM) for measuring the apparent dissociation constant and ligand purity in Ca²⁺ and Mg²⁺ buffer solutions. Progress in Biophysics and Molecular Biology, 116, 203 - 211. (doi: 10.1016/j.pbiomolbio.2014.04.001) (PMID:24836054)
Kay, J.W. , Steven, R.J., McGuigan, J.A.S. and Elder, H. (2008) Automatic determination of ligand purity and apparent dissociation constant (Kapp) in Ca2+/Mg2+ buffer solutions and the Kapp for Ca2+/Mg2+ anion binding in physiological solutions from Ca2+/Mg2+-macroelectrode measurements. Computers in Biology and Medicine, 38(1), pp. 101-110. (doi: 10.1016/j.compbiomed.2007.07.008) (PMID:17854794)
McGuigan, J., Kay, J.W. , Elder, H.Y. and Luthi, D. (2007) Comparison between measured and calculated ionised concentrations in Mg2+/ATP,Mg2+/EDTA and Ca2+/EGTA buffers;influence of changes in temperature, pH and pipetting errors on the ionised concentrations. Magnesium Research, 20(1), pp. 72-81. (doi: 10.1684/mrh.2007.0092) (PMID:17536492)
McGuigan, J.A.S., Kay, J.W. and Elder, H.Y. (2006) Critical review of the methods used to measure the apparent dissociation constant and ligand purity in Ca2+ and Mg2+ buffer solutions. Progress in Biophysics and Molecular Biology, 92, pp. 333-370. (doi: 10.1016/j.pbiomolbio.2006.05.001) (PMID:16887174)
Reid, C.A., Moss, V.A., Kay, J.W. and Elder, H.Y. (1990) Towards automatic segmentation and classification of mineralised bone. Transactions of the Royal Microscopical Society, pp. 543-546.