Professor Tomasz Guzik

Honorary Senior Research Fellow (School of Cardiovascular & Metabolic Health)

email: Tomasz.Guzik@glasgow.ac.uk

Queens Institute of Medical Research, 47 Little France Crescent, EH16 4TJ

Import to contacts

Research interests

Leader: Vascular Research

Member:

Publications

List by: Type | Date

Jump to: 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006 | 2005 | 2004 | 2003 | 2002 | 2001 | 2000

Number of items: 189.

2024

Olowoyo, P., Maffia, P. , Guzik, T. J. and Owolabi, M. (2024) Understanding and controlling the increasing burden of cardiovascular diseases in Africa. Cardiovascular Research, (doi: 10.1093/cvr/cvad173) (PMID:38442189) (In Press)

Olowoyo, P. et al. (2024) Priorities to reduce the burden of hypertension in Africa through ACHIEVE. Lancet Global Health, 12(2), e192-e193. (doi: 10.1016/S2214-109X(23)00540-5) (PMID:38245107)

Guzik, T. J., Nosalski, R., Maffia, P. and Drummond, G. R. (2024) Immune and inflammatory mechanisms in hypertension. Nature Reviews Cardiology, (doi: 10.1038/s41569-023-00964-1) (PMID:38172242) (Early Online Publication)

2023

Caiazzo, E. et al. (2023) Circulating cytokines and risk of developing hypertension: a systematic review and meta-analysis. Pharmacological Research, (doi: 10.1016/j.phrs.2023.107050) (PMID:38159784) (In Press)

Siedlinski, M. et al. (2023) Genetic analyses identify brain structures related to cognitive impairment associated with elevated blood pressure. European Heart Journal, 44(23), pp. 2114-2125. (doi: 10.1093/eurheartj/ehad101) (PMID:36972688) (PMCID:PMC10281555)

Schutte, A. E. et al. (2023) Addressing global disparities in blood pressure control: perspectives of the International Society of Hypertension. Cardiovascular Research, 119(2), pp. 381-409. (doi: 10.1093/cvr/cvac130) (PMID:36219457) (PMCID:PMC9619669)

Crea, F., Guzik, T. and Kavaney, A. F. (2023) The Journal Citation Indicator: what is the relevance of this new metric? European Heart Journal, 44(4), pp. 243-244. (doi: 10.1093/eurheartj/ehac795) (PMID:36680422)

2022

Murray, E. C. , Delles, C. , Orzechowski, P., Renc, P., Sitek, A., Wagenaar, J. and Guzik, T. J. (2022) Vascular phenotypes in early hypertension. Journal of Human Hypertension, (doi: 10.1038/s41371-022-00794-7) (Early Online Publication)

Guzik, T. J., Sipido, K. R., Brown, S. K. and Casadei, B. (2022) At the forefront of basic and translational Cardiovascular Research for fifty-five years and counting. Cardiovascular Research, 118(16), pp. 3163-3165. (doi: 10.1093/cvr/cvac169) (PMID:36333941)

Pugliese, N. R., Pellicori, P. , Filidei, F., De Biase, N., Maffia, P. , Guzik, T. J., Masi, S., Taddei, S. and Cleland, J. G.F. (2022) Inflammatory pathways in heart failure with preserved left ventricular ejection fraction: implications for future interventions. Cardiovascular Research, 118(18), pp. 3536-3555. (doi: 10.1093/cvr/cvac133) (PMID:36004819) (PMCID:PMC9897694)

van der Velden, J. et al. (2022) Animal models and animal-free innovations for cardiovascular research: current status and routes to be explored. Consensus document of the ESC working group on myocardial function and the ESC Working Group on Cellular Biology of the Heart. Cardiovascular Research, 118(15), pp. 3016-3051. (doi: 10.1093/cvr/cvab370) (PMID:34999816)

Xu, X. et al. (2022) Contributions of obesity to kidney health and disease: insights from mendelian randomization and the human kidney transcriptomics. Cardiovascular Research, 118(15), pp. 3151-3161. (doi: 10.1093/cvr/cvab357) (PMID:34893803)

Evans, P. C. et al. (2022) From novel discovery tools and biomarkers to precision medicine - basic cardiovascular science highlights of 2021/2022. Cardiovascular Research, 118(13), pp. 2754-2767. (doi: 10.1093/cvr/cvac114) (PMID:35899362) (PMCID:PMC9384606)

Tomaszewski, M. et al. (2022) Kidney omics in hypertension: from statistical associations to biological mechanisms and clinical applications. Kidney International, 102(3), pp. 492-505. (doi: 10.1016/j.kint.2022.04.045) (PMID:35690124)

Ananthaseshan, S. et al. (2022) Red blood cell distribution width is associated with increased interactions of blood cells with vascular wall. Scientific Reports, 12, 13676. (doi: 10.1038/s41598-022-17847-z) (PMID:35953533) (PMCID:PMC9366818)

Szczepaniak, P. et al. (2022) Breast cancer chemotherapy induces vascular dysfunction and hypertension through NOX4 dependent mechanism. Journal of Clinical Investigation, 132(13), e149117. (doi: 10.1172/JCI149117) (PMID:35617030) (PMCID:PMC9246378)

Pinto, R. D., Monaco, A., Ortu, E., Czesnikiewicz-Guzik, M. , Aguilera, E. M., Giannoni, M., D'Aiuto, F., Guzik, T. J., Ferri, C. and Pietropaoli, D. (2022) Access to dental care and blood pressure profiles in adults with high socioeconomic status. Journal of Periodontology, 93(7), pp. 1060-1071. (doi: 10.1002/jper.21-0439) (PMID:34726790)

Lip, S. , McCallum, L., Delles, C. , McClure, J. D. , Guzik, T., Berry, C. , Touyz, R. and Padmanabhan, S. (2022) Rationale and design for the LOnger-term effects of SARS-CoV-2 INfection on blood Vessels And blood pRessure (LOCHINVAR). Open Heart, 9(1), e002057. (doi: 10.1136/openhrt-2022-002057) (PMID:35750422) (PMCID:PMC9234432)

Diaz-Canestro, C. et al. (2022) MMP-2 knockdown blunts age-dependent carotid stiffness by decreasing elastin degradation and augmenting eNOS activation. Cardiovascular Research, 118(10), pp. 2385-2396. (doi: 10.1093/cvr/cvab300) (PMID:34586381)

Mohanta, S. K. et al. (2022) Neuroimmune cardiovascular interfaces control atherosclerosis. Nature, 605(7908), pp. 152-159. (doi: 10.1038/s41586-022-04673-6) (PMID:35477759)

Camargo, L. L. et al. (2022) Central role of c-Src in NOX5- mediated redox signaling in vascular smooth muscle cells in human hypertension. Cardiovascular Research, 118(5), pp. 1359-1373. (doi: 10.1093/cvr/cvab171) (PMID:34320175) (PMCID:PMC8953456)

Caiazzo, E., Rezig, A. O.M. , Bruzzese, D., Ialenti, A., Cicala, C., Cleland, J. G.F. , Guzik, T. J., Maffia, P. and Pellicori, P. (2022) Systemic administration of glucocorticoids, cardiovascular complications and mortality in patients hospitalised with COVID-19, SARS, MERS or influenza: a systematic review and meta-analysis of randomised trials. Pharmacological Research, 176, 106053. (doi: 10.1016/j.phrs.2021.106053) (PMID:34979235) (PMCID:PMC8719379)

2021

Szczepaniak, P., Mikołajczyk, T. P., Cześnikiewicz-Guzik, M. and Guzik, T. J. (2021) Periodontitis as an inflammatory trigger in hypertension: from basic immunology to clinical implications. Kardiologia Polska, 79(11), pp. 1206-1214. (doi: 10.33963/KP.a2021.0161) (PMID:34847238)

Murray, E. C. , Nosalski, R., MacRitchie, N., Tomaszewski, M., Maffia, P. , Harrison, D. G. and Guzik, T. J. (2021) Therapeutic targeting of inflammation in hypertension: from novel mechanisms to translational perspective. Cardiovascular Research, 117(13), pp. 2589-2609. (doi: 10.1093/cvr/cvab330) (PMID:34698811)

MacRitchie, N., Noonan, J., Guzik, T. J. and Maffia, P. (2021) Molecular imaging of cardiovascular inflammation. British Journal of Pharmacology, 178(21), pp. 4216-4245. (doi: 10.1111/bph.15654) (PMID:34378206)

Touyz, R. M. et al. (2021) Cardiovascular and renal risk factors and complications associated with COVID-19. CJC Open, 3(10), pp. 1257-1272. (doi: 10.1016/j.cjco.2021.05.020) (PMID:34151246) (PMCID:PMC8205551)

Alves-Lopes, R. et al. (2021) Selective inhibition of the C-domain of ACE (angiotensin-converting enzyme) combined with inhibition of NEP (neprilysin): a potential new therapy for hypertension. Hypertension, 78(3), pp. 604-616. (doi: 10.1161/HYPERTENSIONAHA.121.17041) (PMID:34304582) (PMCID:PMC8357049)

MacRitchie, N., Di Francesco, V., Ferreira, M. F. M. M., Guzik, T. J., Decuzzi, P. and Maffia, P. (2021) Nanoparticle theranostics in cardiovascular inflammation. Seminars in Immunology, 56, 101536. (doi: 10.1016/j.smim.2021.101536) (PMID:34862118) (PMCID:PMC8811479)

Figtree, G. A. et al. (2021) A call to action for new global approaches to cardiovascular disease drug solutions. Circulation, 144(2), pp. 159-169. (doi: 10.1161/CIR.0000000000000981) (PMID:33876947)

Evans, P., Wojta, J., Hoefer, I. E., Waltenberger, J., Guzik, T., Badimon, L. and Weber, C. (2021) The year in basic vascular biology research: from mechanoreceptors and nets to smartphone data and omics. Cardiovascular Research, 117(8), pp. 1814-1822. (doi: 10.1093/cvr/cvab105) (PMID:33744925) (PMCID:PMC8083796)

Mikolajczyk, T. P., Szczepaniak, P., Vidler, F., Maffia, P. , Graham, G. J. and Guzik, T. J. (2021) Role of inflammatory chemokines in hypertension. Pharmacology and Therapeutics, 223, 107799. (doi: 10.1016/j.pharmthera.2020.107799) (PMID:33359600)

da Silva, R. d. N. O., Santos-Eichler, R. A., Dias, C., Rodrigues, S. F., Skiba, D. S., Landgraf, R. G., de Carvalho, M. H. C., Guzik, T., Fock, R. A. and Akamine, E. H. (2021) Immune spleen cells attenuate the inflammatory profile of the mesenteric perivascular adipose tissue in obese mice. Scientific Reports, 11, 11153. (doi: 10.1038/s41598-021-90600-0) (PMID:34045574) (PMCID:PMC8160359)

Eales, J. M. et al. (2021) Uncovering genetic mechanisms of hypertension through multi-omic analysis of the kidney. Nature Genetics, 53(5), pp. 630-637. (doi: 10.1038/s41588-021-00835-w) (PMID:33958779)

Jozefczuk, E., Szczepaniak, P., Guzik, T. J. and Siedlinski, M. (2021) Silencing of sphingosine kinase 1 affects maturation pathways in mouse neonatal cardiomyocytes. International Journal of Molecular Sciences, 22(7), 3616. (doi: 10.3390/ijms22073616) (PMID:33807180) (PMCID:PMC8037404)

Sharma, S. et al. (2021) Periodontal therapy and treatment of hypertension – alternative to the pharmacological approach. A systematic review and meta-analysis. Pharmacological Research, 166, 105511. (doi: 10.1016/j.phrs.2021.105511) (PMID:33617973)

Guzik, T. et al. (2021) Rivaroxaban plus aspirin in obese and overweight patients with vascular disease in the COMPASS trial. Journal of the American College of Cardiology, 77(5), pp. 511-525. (doi: 10.1016/j.jacc.2020.11.061) (PMID:33538248)

2020

Evans, P. C. et al. (2020) Endothelial dysfunction in COVID-19: a position paper of the ESC Working Group for Atherosclerosis and Vascular Biology, and the ESC Council of Basic Cardiovascular Science. Cardiovascular Research, 116(14), pp. 2177-2184. (doi: 10.1093/cvr/cvaa230) (PMID:32750108) (PMCID:PMC7454368)

Nosalski, R., Mikolajczyk, T., Siedlinski, M., Saju, B., Koziol, J., Maffia, P. and Guzik, T.J. (2020) Nox1/4 inhibition exacerbates age dependent perivascular inflammation and fibrosis in a model of spontaneous hypertension. Pharmacological Research, 161, 105235. (doi: 10.1016/j.phrs.2020.105235) (PMID:33131726) (PMCID:PMC8316606)

Henderson, I., Caiazzo, E., McSharry, C., Guzik, T. J. and Maffia, P. (2020) Why do some asthma patients respond poorly to glucocorticoid therapy? Pharmacological Research, 160, 105189. (doi: 10.1016/j.phrs.2020.105189) (PMID:32911071) (PMCID:PMC7672256)

Sabir, S. R., Thomson, E. C. , Guzik, T. J., D’Acquisto, F. and Maffia, P. (2020) COVID-19: the new immune challenge. Frontiers for Young Minds, 8, 582971. (doi: 10.3389/frym.2020.582971)

Guzik, T. J. et al. (2020) COVID-19 and the cardiovascular system: implications for risk assessment, diagnosis, and treatment options. Cardiovascular Research, 116(10), pp. 1666-1687. (doi: 10.1093/cvr/cvaa106) (PMID:32352535) (PMCID:PMC7197627)

Murray, E. , Tomaszewski, M. and Guzik, T. J. (2020) Binding of SARS-CoV-2 and angiotensin-converting enzyme 2: clinical implications. Cardiovascular Research, 116(7), e87-e89. (doi: 10.1093/cvr/cvaa096) (PMID:32301968) (PMCID:PMC7184453)

Adão, R. and Guzik, T. J. (2020) Inside the heart of COVID-19. Cardiovascular Research, 116(6), (doi: 10.1093/cvr/cvaa086) (PMID:32266937)

Siedlinski, M. et al. (2020) White blood cells and blood pressure: a Mendelian randomization study. Circulation, 141(16), pp. 1307-1317. (doi: 10.1161/CIRCULATIONAHA.119.045102) (PMID:32148083) (PMCID:PMC7176352)

Nosalski, R. et al. (2020) T cell-derived miRNA-214 mediates perivascular fibrosis in hypertension. Circulation Research, 126, pp. 988-1003. (doi: 10.1161/CIRCRESAHA.119.315428) (PMID:32065054) (PMCID:PMC7147427)

Filipek, A., Mikołajczyk, T. P., Guzik, T. J. and Naruszewicz, M. (2020) Oleacein and foam cell formation in human monocyte-derived macrophages: a potential strategy against early and advanced atherosclerotic lesions. Pharmaceuticals, 13(4), e64. (doi: 10.3390/ph13040064) (PMID:32283795)

Madhur, M. S., Kirabo, A., Guzik, T. J. and Harrison, D. (2020) From rags to riches. Hypertension, 75(4), pp. 930-934. (doi: 10.1161/hypertensionaha.119.14612) (PMID:32078385)

Gurgone, D., McShane, L. , McSharry, C., Guzik, T. J. and Maffia, P. (2020) Cytokines at the interplay between asthma and atherosclerosis? Frontiers in Pharmacology, 11, 166. (doi: 10.3389/fphar.2020.00166)

Krzyżewski, R. M., Kliś, K. M., Kwinta, B. M., Stachura, K., Guzik, T. J. and Gąsowski, J. (2020) High leukocyte count and risk of poor outcome after subarachnoid hemorrhage: a meta-analysis. World Neurosurgery, 135, e541-e547. (doi: 10.1016/j.wneu.2019.12.056) (PMID:31863891)

Rios, F. J. et al. (2020) Chanzyme TRPM7 protects against cardiovascular inflammation and fibrosis. Cardiovascular Research, 116(3), pp. 721-735. (doi: 10.1093/cvr/cvz164) (PMID:31250885) (PMCID:PMC7252442)

Luc, K., Schramm-Luc, A., Guzik, T.J. and Mikolajczyk, T.P. (2020) Oxidative stress and inflammatory markers in prediabetes and diabetes. Journal of Physiology and Pharmacology, 70(6), pp. 809-824. (doi: 10.26402/jpp.2019.6.01) (PMID:32084643)

MacRitchie, N. et al. (2020) The aorta can act as site of naïve CD4+ T cell priming. Cardiovascular Research, 116(2), pp. 306-316. (doi: 10.1093/cvr/cvz102) (PMID:30980670)

Muñoz Aguilera, E. et al. (2020) Periodontitis is associated with hypertension: a systematic review and meta-analysis. Cardiovascular Research, 116(1), pp. 28-39. (doi: 10.1093/cvr/cvz201) (PMID:31549149)

2019

Czesnikiewicz-Guzik, M. et al. (2019) Causal association between periodontitis and hypertension: evidence from Mendelian randomization and a randomized controlled trial of non-surgical periodontal therapy. European Heart Journal, 40(42), pp. 3459-3470. (doi: 10.1093/eurheartj/ehz646) (PMID:31504461) (PMCID:PMC6837161)

Eales, J. M. et al. (2019) The human Y chromosome exerts pleiotropic effects on susceptibility to atherosclerosis. Arteriosclerosis, Thrombosis, and Vascular Biology, 39(11), pp. 2386-2401. (doi: 10.1161/ATVBAHA.119.312405) (PMID:31644355) (PMCID:PMC6818981)

Sagan, A. et al. (2019) T cells are dominant population in human abdominal aortic aneurysms and their infiltration in the perivascular tissue correlates with disease severity. Frontiers in Immunology, 10, 1979. (doi: 10.3389/fimmu.2019.01979) (PMID:31552015) (PMCID:PMC6736986)

Batko, B., Urbański, K., Świerkot, J., Wiland, P., Raciborski, F., Jędrzejewski, M., Koziej, M., Czesnikiewicz-Guzik, M. , Guzik, T. and Stajszczyk, M. (2019) Comorbidity burden and clinical characteristics of patients with difficult-to-control rheumatoid arthritis. Clinical Rheumatology, 38(9), pp. 2473-2481. (doi: 10.1007/s10067-019-04579-1) (PMID:31076943)

Moayyedi, P. et al. (2019) Safety of proton pump inhibitors based on a large, multi-year, randomized trial of patients receiving rivaroxaban or aspirin. Gastroenterology, 157(3), 682-691.e2. (doi: 10.1053/j.gastro.2019.05.056) (PMID:31152740)

Drummond, G. R., Vinh, A., Guzik, T. J. and Sobey, C. G. (2019) Immune mechanisms of hypertension. Nature Reviews Immunology, 19(8), pp. 517-532. (doi: 10.1038/s41577-019-0160-5) (PMID:30992524)

Maffia, P. and Guzik, T. J. (2019) When, where and how to target vascular inflammation in the post-CANTOS era? European Heart Journal, 40(30), pp. 2492-2494. (doi: 10.1093/eurheartj/ehz133) (PMID:30929007) (PMCID:PMC6685316)

Moayyedi, P. et al. (2019) Pantoprazole to prevent gastroduodenal events in patients receiving rivaroxaban and/or aspirin in a randomized, double-blind, placebo-controlled trial. Gastroenterology, 157(2), 403-412.e5. (doi: 10.1053/j.gastro.2019.04.041) (PMID:31054846)

Czesnikiewicz-Guzik, M. , Nosalski, R., Mikolajczyk, T. P., Vidler, F., Dohnal, T., Dembowska, E., Graham, D. , Harrison, D. G. and Guzik, T. J. (2019) Th1 type immune responses to Porphyromonas gingivalis antigens exacerbate angiotensin II dependent hypertension and vascular dysfunction. British Journal of Pharmacology, 176(12), pp. 1922-1931. (doi: 10.1111/bph.14536) (PMID:30414380) (PMCID:PMC6534780)

Mikolajczyk, T. P. et al. (2019) 1,2,3,4,6 penta-O -galloyl-β-D-glucose modulates perivascular inflammation and prevents vascular dysfunction in angiotensin II-induced hypertension. British Journal of Pharmacology, 176(12), pp. 1951-1965. (doi: 10.1111/bph.14583) (PMID:30658013) (PMCID:PMC6534792)

Noonan, J., Grassia, G., MacRitchie, N., Garside, P. , Guzik, T. J., Bradshaw, A. C. and Maffia, P. (2019) A novel triple-cell two-dimensional model to study immune-vascular interplay in atherosclerosis. Frontiers in Immunology, 10, 849. (doi: 10.3389/fimmu.2019.00849) (PMID:31068936) (PMCID:PMC6491724)

Guzik, T. J. (2019) Diagnostic and therapeutic targeting of inflammation. In: Touyz, R. M. and Delles, C. (eds.) Textbook of Vascular Medicine. Springer: Cham, pp. 239-246. ISBN 9783030164805 (doi: 10.1007/978-3-030-16481-2_22)

Mercer, J. and Guzik, T. J. (2019) Atherosclerosis. In: Touyz, R. M. and Delles, C. (eds.) Textbook of Vascular Medicine. Springer: Cham, pp. 215-228. ISBN 9783030164805 (doi: 10.1007/978-3-030-16481-2_20)

2018

Podolec, J. et al. (2018) Serum rantes, transforming growth factor-β1 and interleukin-6 levels correlate with cardiac muscle fibrosis in patients with aortic valve stenosis. Journal of Physiology and Pharmacology, 69(4), pp. 615-623. (doi: 10.26402/jpp.2018.4.12) (PMID:30552305)

Mazur, M. et al. (2018) Effects of controlled physical activity on immune cell phenotype in peripheral blood in prehypertension - studies in preclinical model and randomised crossover study. Journal of Physiology and Pharmacology, 69(6), pp. 875-887. (doi: 10.26402/jpp.2018.6.12) (PMID:30898984)

Guzik, T. J. et al. (2018) What matters in Cardiovascular Research? Scientific discovery driving clinical delivery. Cardiovascular Research, 114(12), pp. 1565-1568. (doi: 10.1093/cvr/cvy214)

Batko, B. et al. (2018) Microvascular dysfunction in ankylosing spondylitis is associated with disease activity and is improved by anti-TNF treatment. Scientific Reports, 8, 13205. (doi: 10.1038/s41598-018-31550-y) (PMID:30181568) (PMCID:PMC6123474)

Loperena, R. et al. (2018) Hypertension and increased endothelial mechanical stretch promote monocyte differentiation and activation: roles of STAT3, interleukin 6 and hydrogen peroxide. Cardiovascular Research, 114(11), pp. 1547-1563. (doi: 10.1093/cvr/cvy112) (PMID:29800237) (PMCID:PMC6106108)

Small, H. Y., Migliarino, S., Czesnikiewicz-Guzik, M. and Guzik, T. J. (2018) Hypertension: focus on autoimmunity and oxidative stress. Free Radical Biology and Medicine, 125, pp. 104-115. (doi: 10.1016/j.freeradbiomed.2018.05.085) (PMID:29857140)

Maffia, P. , Nosalski, R. and Guzik, T. J. (2018) Monocytes M(MP)aking way for T cell vascular infiltration. Circulation Research, 123(6), pp. 638-640. (doi: 10.1161/CIRCRESAHA.118.313668) (PMID:30355241)

Guzik, T. J. and Cosentino, F. (2018) Epigenetics and immunometabolism in diabetes and aging. Antioxidants and Redox Signaling, 29(3), pp. 257-274. (doi: 10.1089/ars.2017.7299) (PMID:28891325) (PMCID:PMC6012980)

Podolec, J. et al. (2018) Higher levels of circulating naïve CD8+ CD45RA+ cells are associated with lower extent of coronary atherosclerosis and vascular dysfunction. International Journal of Cardiology, 259, pp. 26-30. (doi: 10.1016/j.ijcard.2018.01.079) (PMID:29579606)

Petrie, J. R. , Guzik, T. J. and Touyz, R. M. (2018) Diabetes, hypertension, and cardiovascular disease: clinical insights and vascular mechanisms. Canadian Journal of Cardiology, 34(5), pp. 575-584. (doi: 10.1016/j.cjca.2017.12.005) (PMID:29459239) (PMCID:PMC5953551)

Wojta, J., Guzik, T. and Pearson, J. D. (2018) Pushing the frontiers of cardiovascular biology. Cardiovascular Research, 114(3), e22-e22. (doi: 10.1093/cvr/cvy025) (PMID:29481651)

Almabrouk, T. A.M. , White, A. D., Ugusman, A. B., Skiba, D. S., Katwan, O. J., Alganga, H., Guzik, T. J., Touyz, R. M. , Salt, I. P. and Kennedy, S. (2018) High fat diet attenuates the anticontractile activity of aortic PVAT via a mechanism involving AMPK and reduced adiponectin secretion. Frontiers in Physiology, 9, 51. (doi: 10.3389/fphys.2018.00051) (PMID:29479319) (PMCID:PMC5812172)

Anand, S. S. et al. (2018) Rivaroxaban with or without aspirin in patients with stable peripheral or carotid artery disease: an international, randomised, double-blind, placebo-controlled trial. Lancet, 391(10117), pp. 219-229. (doi: 10.1016/S0140-6736(17)32409-1) (PMID:29132880)

Connolly, S. J. et al. (2018) Rivaroxaban with or without aspirin in patients with stable coronary artery disease: an international, randomised, double-blind, placebo-controlled trial. Lancet, 391(10117), pp. 205-218. (doi: 10.1016/S0140-6736(17)32458-3) (PMID:29132879)

Guzik, T. J. (2018) Cardiovascular Research: new challenges and new horizons. Cardiovascular Research, 114(1), pp. 1-2. (doi: 10.1093/cvr/cvx229) (PMID:29253088)

Noonan, J. et al. (2018) In vivo multiplex molecular imaging of vascular inflammation using surface-enhanced Raman spectroscopy. Theranostics, 8(22), pp. 6195-6209. (doi: 10.7150/thno.28665) (PMID:30613292) (PMCID:PMC6299693)

2017

Skiba, D.S. et al. (2017) Anti‐atherosclerotic effect of the angiotensin 1–7 mimetic AVE0991 is mediated by inhibition of perivascular and plaque inflammation in early atherosclerosis. British Journal of Pharmacology, 174(22), pp. 4055-4069. (doi: 10.1111/bph.13685) (PMID:27935022) (PMCID:PMC5659999)

Eikelboom, J. W. et al. (2017) Rivaroxaban with or without aspirin in stable cardiovascular disease. New England Journal of Medicine, 377(14), pp. 1319-1330. (doi: 10.1056/NEJMoa1709118) (PMID:28844192)

Guzik, T. J. and Channon, K. M. (2017) Linking noise to cardiovascular disease pathogenesis. European Heart Journal, 38(37), pp. 2850-2852. (doi: 10.1093/eurheartj/ehx217) (PMID:28633421)

Guzik, T. J. and Touyz, R. M. (2017) Oxidative stress, inflammation, and vascular aging in hypertension. Hypertension, 70(4), pp. 660-667. (doi: 10.1161/HYPERTENSIONAHA.117.07802) (PMID:28784646)

Nosalski, R. and Guzik, T. J. (2017) Perivascular adipose tissue inflammation in vascular disease. British Journal of Pharmacology, 174(20), pp. 3496-3513. (doi: 10.1111/bph.13705) (PMID:28063251)

Bosch, J. et al. (2017) Rationale, design and baseline characteristics of participants in the Cardiovascular Outcomes for People Using Anticoagulation Strategies (COMPASS) trial. Canadian Journal of Cardiology, 33(8), pp. 1027-1035. (doi: 10.1016/j.cjca.2017.06.001) (PMID:28754388)

Small, H. Y., Cornelius, D. C., Guzik, T. J. and Delles, C. (2017) Natural killer cells in placentation and cancer: Implications for hypertension during pregnancy. Placenta, 56, pp. 59-64. (doi: 10.1016/j.placenta.2017.03.003) (PMID:28318556)

Guzik, T. J., Skiba, D. S., Touyz, R. M. and Harrison, D. G. (2017) The role of infiltrating immune cells in dysfunctional adipose tissue. Cardiovascular Research, 113(9), pp. 1009-1023. (doi: 10.1093/cvr/cvx108) (PMID:28838042) (PMCID:PMC5852626)

Calvet, D., Amar, L., Rossi, G. P., Laurent, S., Dominiczak, A. F. , Turc, G., Jennings, G., Guzik, T. and Touyz, R. M. (2017) Case of asymptomatic carotid artery stenosis in a hypertensive patient. Hypertension, 69(6), pp. 985-991. (doi: 10.1161/HYPERTENSIONAHA.117.09330) (PMID:28461597)

Guzik, T. J. (2017) Heterogenous treatment effects: secrets for a reliable treat-to-target trial? Cardiovascular Research, 113(7), e18-e20. (doi: 10.1093/cvr/cvx081) (PMID:28525917) (PMCID:PMC5852616)

Nosalski, R., McGinnigle, E., Siedlinski, M. and Guzik, T. J. (2017) Novel immune mechanisms in hypertension and cardiovascular risk. Current Cardiovascular Risk Reports, 11(4), 12. (doi: 10.1007/s12170-017-0537-6)

Siedlinski, M. et al. (2017) Vascular transcriptome profiling identifies Sphingosine kinase 1 as a modulator of angiotensin II-induced vascular dysfunction. Scientific Reports, 7, 44131. (doi: 10.1038/srep44131) (PMID:28276483) (PMCID:PMC5343497)

Maciąg, J. et al. (2017) Systemic T cells and monocyte characteristics in patients with denture stomatitis. Journal of Prosthodontics, 26(1), pp. 19-28. (doi: 10.1111/jopr.12447) (PMID:26883670)

Osmenda, G., Maciąg, J., Wilk, G., Maciąg, A., Nowakowski, D., Loster, J., Dembowska, E., Robertson, D. , Guzik, T. and Czesnikiewicz-Guzik, M. (2017) Treatment of denture-related stomatitis improves endothelial function assessed by flow-mediated vascular dilation. Archives of Medical Science, 13(1), pp. 66-74. (doi: 10.5114/aoms.2017.64715)

Urbanski, K. et al. (2017) CD14+CD16++ “nonclassical” monocytes are associated with endothelial dysfunction in patients with coronary artery disease. Thrombosis and Haemostasis, 117(5), pp. 971-980. (doi: 10.1160/TH16-08-0614) (PMID:28229168)

2016

Harrison, D.G. and Guzik, T. J. (2016) Macrophages come to mind as keys to cognitive decline. Journal of Clinical Investigation, 126(12), pp. 4393-4395. (doi: 10.1172/JCI91277) (PMID:27841765)

Small, H. Y., Nosalski, R., Morgan, H., Beattie, E., Guzik, T., Graham, D. and Delles, C. (2016) The role of tumor necrosis factor-α and natural killer cells in uterine artery function and pregnancy outcome in the stroke prone spontaneously hypertensive rat. Hypertension, 68(5), pp. 1298-1307. (doi: 10.1161/HYPERTENSIONAHA.116.07933) (PMID:27733586) (PMCID:PMC5058643)

Urbanski, K., Filip, G., Filip, M., Ludew, D., Szczepaniak, P., Nosalski, R.,, Sagan, A., Mikolajczyk, T., Kapelak, B. and Guzik, T.J. (2016) [OP.2D.04] Perivascular T regulatory cells and endothelial dysfunction in human atherosclerosis. Journal of Hypertension, 34(S2), e24-e25. (doi: 10.1097/01.hjh.0000491394.17973.0a) (PMID:27508639)

Itani, H. A. et al. (2016) Activation of human t cells in hypertension: studies of humanized mice and hypertensive humans. Hypertension, 68(1), pp. 123-132. (doi: 10.1161/HYPERTENSIONAHA.116.07237) (PMID:27217403)

Mikolajczyk, T.P. et al. (2016) Role of chemokine RANTES in the regulation of perivascular inflammation, T-cell accumulation, and vascular dysfunction in hypertension. FASEB Journal, 30(5), pp. 1987-1999. (doi: 10.1096/fj.201500088R) (PMID:26873938) (PMCID:PMC4836375)

Podolec, J., Kopec, G., Niewiara, L., Komar, M., Guzik, B., Bartus, K., Tomkiewicz-Pajak, L., Guzik, T.J., Plazak, W. and Zmudka, K. (2016) Chemokine RANTES is increased at early stages of coronary artery disease. Journal of Physiology and Pharmacology, 67(2), pp. 321-328.

Mikolajczyk, T. P., Osmenda, G., Batko, B., Wilk, G., Krezelok, M., Skiba, D., Sliwa, T., Pryjma, J. R. and Guzik, T. J. (2016) Heterogeneity of peripheral blood monocytes, endothelial dysfunction and subclinical atherosclerosis in patients with systemic lupus erythematosus. Lupus, 25(1), pp. 18-27. (doi: 10.1177/0961203315598014) (PMID:26251402)

2015

Chan, C. T. et al. (2015) Obligatory role for B cells in the development of angiotensin II–dependent hypertension. Hypertension, 66(5), pp. 1023-1033. (doi: 10.1161/hypertensionaha.115.05779) (PMID:26351030)

Moore, J. P. et al. (2015) M2 macrophage accumulation in the aortic wall during angiotensin ii infusion in mice is associated with fibrosis, elastin loss and elevated blood pressure. American Journal of Physiology: Heart and Circulatory Physiology, 309(5), H906-H917. (doi: 10.1152/ajpheart.00821.2014) (PMID:26071547)

2014

Mikolajczyk, T.P., Skiba, D., Batko, B., Krezelok, M., Wilkie, G., Osmenda, G., Pryjma, J.R. and Guzik, T.J. (2014) Characterization of the impairment of the uptake of apoptotic polymorphonuclear cells by monocyte subpopulations in systemic lupus erythematosus. Lupus, 23(13), pp. 1358-1369. (doi: 10.1177/0961203314541316)

Kirabo, A. et al. (2014) DC isoketal-modified proteins activate T cells and promote hypertension. Journal of Clinical Investigation, 124(10), pp. 4642-4656. (doi: 10.1172/JCI74084) (PMID:25244096) (PMCID:PMC4220659)

Guzik, T. J. and Mikolajczyk, T. (2014) In search of the T cell involved in hypertension and target organ damage. Hypertension, 64(2), pp. 224-226. (doi: 10.1161/HYPERTENSIONAHA.114.03340)

Mrowiecki, W., Sagan, A., Guzik, B. G., Sliwa, T., Ignacak, A., Mrowiecki, T. and Guzik, T. J. (2014) Inflammatory aortic abdominal aneurysm – immunophenotypic characterization of inflammatory infiltrate. Archives of Medical Science, 6, pp. 1258-1262. (doi: 10.5114/aoms.2014.47836) (PMID:25624867) (PMCID:PMC4296082)

Konior, A., Schramm, A., Czesnikiewicz-Guzik, M. and Guzik, T. J. (2014) NADPH oxidases in vascular pathology. Antioxidants and Redox Signaling, 20(17), pp. 2794-2814. (doi: 10.1089/ars.2013.5607)

Guzik, T. J., Schramm, A. and Czesnikiewicz-Guzik, M. (2014) Functional implications of Reactive Oxygen Species (ROS) in human blood vessels. In: Laher, I. (ed.) Systems Biology of Free Radicals and Antioxidants. Springer, pp. 1155-1176. ISBN 9783642300172 (doi: 10.1007/978-3-642-30018-9_178)

Guzik, T. J. and Grodzicki, T. (2014) "Radical" link between chronic obstructive pulmonary disease and cardiovascular disease? Hypertension, 63(3), pp. 444-446. (doi: 10.1161/HYPERTENSIONAHA.113.02623) (PMID:24324039)

Maciąg, J. et al. (2014) Denture-related stomatitis is associated with endothelial dysfunction. BioMed Research International, 2014, p. 474016. (doi: 10.1155/2014/474016)

Toh, B.-H., Bobik, A., Kyaw, T. S., Drummond, G. R., Sobey, C. G. and Guzik, T. J. (2014) Immune mechanisms in vascular disease and stroke. BioMed Research International, 2014, p. 730691. (doi: 10.1155/2014/730691)

Wolkow, P. P. et al. (2014) GTP cyclohydrolase I gene polymorphisms are associated with endothelial dysfunction and oxidative stress in patients with type 2 diabetes mellitus. PLoS ONE, 9(11), e108587. (doi: 10.1371/journal.pone.0108587) (PMID:25369080) (PMCID:PMC4219671)

2013

Guzik, B. et al. (2013) Mechanisms of oxidative stress in human aortic aneurysms — association with clinical risk factors for atherosclerosis and disease severity. International Journal of Cardiology, 168(3), pp. 2389-2396. (doi: 10.1016/j.ijcard.2013.01.278) (PMID:23506637) (PMCID:PMC3819986)

Sulicka, J., Surdacki, A., Mikołajczyk, T., Strach, M., Gryglewska, B., Ćwiklińska, M., Balwierz, W., Guzik, T. and Grodzicki, T. K. (2013) Elevated markers of inflammation and endothelial activation and increased counts of intermediate monocytes in adult survivors of childhood acute lymphoblastic leukemia. Immunobiology, 218(5), pp. 810-816. (doi: 10.1016/j.imbio.2012.09.003) (PMID:23182707)

Prejbisz, A. et al. (2013) 22-year-old patient with malignant hypertension associated with primary aldosteronism. Journal of Human Hypertension, 27(2), pp. 138-140. (doi: 10.1038/jhh.2012.26) (PMID:22739770)

Urbański, K., Nowak, M. and Guzik, T.J. (2013) [Oxidative stress and vascular function]. Postepy Biochemii, 59(4), pp. 424-431. (PMID:24745173)

Wilk, G., Osmenda, G., Matusik, P., Nowakowski, D., Jasiewicz‑Honkisz, B., Ignacak, A., Czesnikiewicz-Guzik, M. and Guzik, T. J. (2013) Endothelial function assessment in atherosclerosis: Comparison of brachial artery flow‑mediated vasodilation and peripheral arterial tonometry. Polish Archives of Internal Medicine, 123(9), pp. 443-452.

2012

Dulak, J. and Guzik, T. J. (2012) Angiogenesis, stem cells, eNOS and inflammation – the many faces of vascular biology. Thrombosis and Haemostasis, 108(5), pp. 801-803. (doi: 10.1160/TH12-10-0729) (PMID:23052221)

Sagan, A., Mrowiecki, W., Mikolajczyk, T. P., Urbanski, K., Siedlinski, M., Nosalski, R., Korbut, R. and Guzik, T.J. (2012) Local inflammation is associated with aortic thrombus formation in abdominal aortic aneurysms. Thrombosis and Haemostasis, 108(5), pp. 812-823. (doi: 10.1160/TH12-05-0339) (PMID:22955940)

Ignacak, A., Kasztelnik, M., Sliwa, T., Korbut, R.A., Rajda, K. and Guzik, T.J. (2012) Prolactin--not only lactotrophin. A "new" view of the "old" hormone. Journal of Physiology and Pharmacology, 63(5), pp. 435-443. (PMID:23211297)

Guzik, T. J. and Dulak, J. (2012) Vessel wall – where coagulation meets cell biology and immunology. Thrombosis and Haemostasis, 108(3), pp. 416-418. (doi: 10.1160/TH12-08-0558) (PMID:22898929)

Matusik, P., Guzik, B., Weber, C. and Guzik, T. J. (2012) Do we know enough about the immune pathogenesis of acute coronary syndromes to improve clinical practice? Thrombosis and Haemostasis, 108(3), pp. 443-456. (doi: 10.1160/TH12-05-0341) (PMID:22872109)

Harrison, D. G. and Guzik, T. J. (2012) Studies of the T-cell angiotensin receptor using cre-lox technology: an unan-T-cellpated result. Circulation Research, 110(12), pp. 1543-1545. (doi: 10.1161/CIRCRESAHA.112.271411) (PMID:22679135)

Schramm, A., Matusik, P., Osmenda, G. and Guzik, T. J. (2012) Targeting NADPH oxidases in vascular pharmacology. Vascular Pharmacology, 56(5-6), pp. 216-231. (doi: 10.1016/j.vph.2012.02.012) (PMID:22405985) (PMCID:PMC3378316)

Tendera, M. et al. (2012) [ESC guidelines for the treatment and diagnosis of peripheral artery disease. Guideline includes extracranial carotid artery, vertebral, mesenteric, renal, upper and lower extremity arteries]. Turk Kardiyoloji Dernegi Arsivi, 40 Sup, pp. 5-60. (PMID:27305719)

Jawien, J. et al. (2012) Angiotensin-(1-7) receptor Mas agonist ameliorates progress of atherosclerosis in apoE-knockout mice. Journal of Physiology and Pharmacology, 63(1), pp. 77-85. (PMID:22460464)

2011

Guzik, B. et al. (2011) Mechanisms of increased vascular superoxide production in human varicose veins. Polish Archives of Internal Medicine, 121(9), pp. 279-286. (PMID:0032-3772)

Antoniades, C. et al. (2011) Rapid, direct effects of statin treatment on arterial redox state and nitric oxide bioavailability in human atherosclerosis via tetrahydrobiopterin-mediated endothelial nitric oxide synthase coupling. Circulation, 124(3), pp. 335-345. (doi: 10.1161/CIRCULATIONAHA.110.985150) (PMID:21730307)

Harrison, D. G., Guzik, T. J., Lob, H. E., Madhur, M. S., Marvar, P. J., Thabet, S. R., Vinh, A. and Weyand, C. M. (2011) Inflammation, immunity, and hypertension. Hypertension, 57(2), pp. 132-140. (doi: 10.1161/HYPERTENSIONAHA.110.163576) (PMID:21149826) (PMCID:PMC3028593)

2010

Figtree, G.A., Guzik, T., Robinson, B.G., Channon, K.M. and Watkins, H. (2010) Functional estrogen receptor alpha promoter polymorphism is associated with improved endothelial-dependent vasolidation. International Journal of Cardiology, 143(2), pp. 207-208. (doi: 10.1016/j.ijcard.2008.11.193) (PMID:19157583)

Marvar, P.J., Thabet, S.R., Guzik, T.J., Lob, H.E., McCann, L.A., Weyand, C., Gordon, F.J. and Harrison, D.G. (2010) Central and peripheral mechanisms of T-Lymphocyte activation and vascular inflammation produced by angiotensin II-induced hypertension. Circulation Research, 107(2), pp. 263-270. (doi: 10.1161/CIRCRESAHA.110.217299) (PMID:20558826) (PMCID:PMC2921936)

Lob, H. E., Marvar, P. J., Guzik, T. J., Sharma, S., McCann, L. A., Weyand, C., Gordon, F. J. and Harrison, D. G. (2010) Induction of hypertension and peripheral inflammation by reduction of extracellular superoxide dismutase in the central nervous system. Hypertension, 55(2), pp. 277-283. (doi: 10.1161/HYPERTENSIONAHA.109.142646) (PMID:20008675) (PMCID:PMC2813894)

Madhur, M.S., Lob, H.E., McCann, L.A., Iwakura, Y., Blinder, Y., Guzik, T.J. and Harrison, D.G. (2010) Interleukin 17 promotes angiotensin II-induced hypertension and vascular dysfunction. Hypertension, 55(2), pp. 500-507. (doi: 10.1161/HYPERTENSIONAHA.109.145094) (PMID:20038749) (PMCID:PMC2819301)

Vinh, A., Chen, W., Blinder, Y., Weiss, D., Taylor, W.R., Goronzy, J.J., Weyand, C.M., Harrison, D.G. and Guzik, T.J. (2010) Inhibition and genetic ablation of the B7/CD28 T-Cell costimulation axis prevents experimental hypertension. Circulation, 122(24), pp. 2529-2537. (doi: 10.1161/CIRCULATIONAHA.109.930446) (PMID:21126972) (PMCID:PMC3064430)

2009

Loster, B.W., Czesnikiewicz-Guzik, M. , Bielański, W., Karczewska, E., Loster, J.E., Guzik, T.J., Majewski, S. and Konturek, S.J. (2009) Prevalence and characterization of helicobacter pylori (H. pylori) infection and colonization in dentists. Journal of Physiology and Pharmacology, 60(Sup 8), pp. 13-18.

Guzik, T. J. and Griendling, K. K. (2009) NADPH oxidases: molecular understanding finally reaching the clinical level? Antioxidants and Redox Signaling, 11(10), pp. 2365-2370. (doi: 10.1089/ARS.2009.2615) (PMID:19358633) (PMCID:PMC2821132)

Hoch, N. E., Guzik, T. J., Chen, W., Deans, T., Maalouf, S. A., Gratze, P., Weyand, C. and Harrison, D. G. (2009) Regulation of T-cell function by endogenously produced angiotensin II. American Journal of Physiology: Regulatory, Integrative and Comparative Physiology, 296(2), R208-R216. (doi: 10.1152/ajpregu.90521.2008) (PMID:19073907) (PMCID:PMC2643984)

2008

Malecki, M. T., Osmenda, G., Walus-Miarka, M., Skupien, J., Cyganek, K., Mirkiewicz-Sieradzka, B., damek-Guzik, T. A., Guzik, T.J. and Sieradzki, J. (2008) Retinopathy in type 2 diabetes mellitus is associated with increased intima-media thickness and endothelial dysfunction. European Journal of Clinical Investigation, 38(12), pp. 925-930. (doi: 10.1111/j.1365-2362.2008.02051.x) (PMID:19021717)

Guzik, T.J. et al. (2008) Calcium-dependent NOX5 nicotinamide adenine dinucleotide phosphate oxidase contributes to vascular oxidative stress in human coronary artery disease. Journal of the American College of Cardiology, 52(22), pp. 1803-1809. (doi: 10.1016/j.jacc.2008.07.063)

Harrison, D. G., Guzik, T. J., Goronzy, J. and Weyand, C. (2008) Is hypertension an immunologic disease? Current Cardiology Reports, 10(6), pp. 464-469. (doi: 10.1007/s11886-008-0073-6) (PMID:18950555)

Gongora, M. C. et al. (2008) Loss of extracellular superoxide dismutase leads to acute lung damage in the presence of ambient air. American Journal of Pathology, 173(4), pp. 915-926. (doi: 10.2353/ajpath.2008.080119) (PMID:18787098) (PMCID:PMC2543061)

Antoniades, C. et al. (2008) GCH1 haplotype determines vascular and plasma biopterin availability in coronary artery disease. Journal of the American College of Cardiology, 52(2), pp. 158-165. (doi: 10.1016/j.jacc.2007.12.062) (PMID:18598896) (PMCID:PMC2699614)

Czesnikiewicz-Guzik, M. , Lorkowska, B., Zapała, J., Czajka, M., Szuta, M., Loster, B., Guzik, T.J. and Korbut, R. (2008) NADPH oxidase and uncoupled nitric oxide synthase are major sources of reactive oxygen species in oral squamous cell carcinoma: potential implications for immune regulation in high oxidative stress conditions. Journal of Physiology and Pharmacology, 59(1), pp. 139-152. (PMID:18441394)

Mihułka, K., Batko, B., Skura, A., Krawiec, P., Krzanowski, M., Sułowicz, W., Guzik, T. J. and Adamek-Guzik, T. (2008) [Relapsing polychondritis--a challenge for modern diagnostics and treatment]. Przeglad Lekarski, 65(2), pp. 77-81. (PMID:18663905)

2007

Guzik, T.J., Marvar, P.J., Czesnikiewicz-Guzik, M. and Korbut, R. (2007) Perivascular adipose tissue as a messenger of the brain-vessel axis: role in vascular inflammation and dysfunction. Journal of Physiology and Pharmacology, 58(4), pp. 591-610. (PMID:18195475)

Malecki, M. T., Undas, A., Cyganek, K., Mirkiewicz-Sieradzka, B., Wolkow, P., Osmenda, G., Walus-Miarka, M., Guzik, T. J. and Sieradzki, J. (2007) Plasma asymmetric dimethylarginine (ADMA) is associated with retinopathy in type 2 diabetes. Diabetes Care, 30(11), pp. 2899-2901. (doi: 10.2337/dc07-1138) (PMID:17704346)

Guzik, T. J. and Harrison, D. G. (2007) Endothelial NF-κB as a mediator of kidney damage: the missing link between systemic vascular and renal disease? Circulation Research, 101(3), pp. 227-229. (doi: 10.1161/CIRCRESAHA.107.158295) (PMID:17673681)

Widder, J. D., Guzik, T. J., Mueller, C. F.H., Clempus, R. E., Schmidt, H. H.H.W., Dikalov, S. I., Griendling, K. K., Jones, D. P. and Harrison, D. G. (2007) Role of the multidrug resistance protein-1 in hypertension and vascular dysfunction caused by angiotensin II. Arteriosclerosis, Thrombosis, and Vascular Biology, 27(4), pp. 762-768. (doi: 10.1161/01.ATV.0000259298.11129.a2) (PMID:17272743)

Czesnikiewicz-Guzik, M. , Loster, B., Bielanski, W., Guzik, T.J., Konturek, P.C., Zapala, J. and Konturek, S.J. (2007) Implications of oral Helicobacter pylori for the outcome of its gastric eradication therapy. Journal of Clinical Gastroenterology, 41(2), pp. 145-151. (doi: 10.1097/01.mcg.0000225654.85060.3d)

Harrison, D. G., Gongora, M. C., Guzik, T. J. and Widder, J. (2007) Oxidative stress and hypertension. Journal of the American Society of Hypertension, 1(1), pp. 30-44. (doi: 10.1016/j.jash.2006.11.006) (PMID:20409831)

Guzik, T. J., Hoch, N. E., Brown, K. A., McCann, L. A., Rahman, A., Dikalov, S., Goronzy, J., Weyand, C. and Harrison, D. G. (2007) Role of the T cell in the genesis of angiotensin II–induced hypertension and vascular dysfunction. Journal of Experimental Medicine, 204(10), pp. 2449-2460. (doi: 10.1084/jem.20070657) (PMID:17875676) (PMCID:PMC2118469)

2006

Guzik, T.J., Mangalat, D. and Korbut, R. (2006) Adipocytokines - novel link between inflammation and vascular function? Journal of Physiology and Pharmacology, 57(4), pp. 505-28. (PMID:17229978)

Ryszawa, N., Kawczynska-Drozdz, A., Pryjma, J., Czesnikiewicz-Guzik, M. , Adamek-Guzik, T., Naruszewicz, M., Korbut, R. and Guzik, T.J. (2006) Effects of novel plant antioxidants on platelet superoxide production and aggregation in atherosclerosis. Journal of Physiology and Pharmacology, 57(4), pp. 611-626.

Kawczynska-Drozdz, A., Olszanecki, R., Jawien, J., Brzozowski, T., Pawlik, W. W., Korbut, R. and Guzik, T. J. (2006) Ghrelin inhibits vascular superoxide production in spontaneously hypertensive rats. American Journal of Hypertension, 19(7), pp. 764-767. (doi: 10.1016/j.amjhyper.2006.01.022) (PMID:16814134)

Guzik, T. J. and Harrison, D. G. (2006) Vascular NADPH oxidases as drug targets for novel antioxidant strategies. Drug Discovery Today, 11(11-12), pp. 524-533. (doi: 10.1016/j.drudis.2006.04.003) (PMID:16713904)

Jawien, J., Gajda, M., Rudling, M., Mateuszuk, L., Olszanecki, R., Guzik, T..J., Cichocki, T., Chlopicki, S. and Korbut, R. (2006) Inhibition of five lipoxygenase activating protein (FLAP) by MK-886 decreases atherosclerosis in apoE/LDLR-double knockout mice. European Journal of Clinical Investigation, 36(3), pp. 141-146. (doi: 10.1111/j.1365-2362.2006.01606.x) (PMID:16506957)

Guzik, T. J., Sadowski, J., Guzik, B., Jopek, A., Kapelak, B., Przybyłowski, P., Wierzbicki, K., Korbut, R., Harrison, D. G. and Channon, K. M. (2006) Coronary artery superoxide production and nox isoform expression in human coronary artery disease. Arteriosclerosis, Thrombosis, and Vascular Biology, 26(2), pp. 333-339. (doi: 10.1161/01.ATV.0000196651.64776.51) (PMID:16293794)

Krawiec, P., Batko, B., Skura, A., Adamek-Guzik, T., Czesnikiewicz-Guzik, M. , Krzanowski, M., Rydz-Stryszowska, I., Ryszawa, N. and Guzik, T.J. (2006) Difficulties in differential diagnosis of Sjogren's syndrome and systemic lupus erythematosus. Przeglad Lekarski, 63(5), pp. 278-283.

2005

Czesnikiewicz-Guzik, M. , Bielanski, W., Guzik, T., Loster, B. and Konturek, S.J. (2005) Helicobacter pylori in the oral cavity and its implications for gastric infection, periodontal health, immunology and dyspepsia. Journal of Physiology and Pharmacology, 56(Sup 6), pp. 77-89.

Kim, Y. M., Guzik, T. J., Hua Zhang, Y., Hua Zhang, M., Kattach, H., Ratnatunga, C., Pillai, R., Channon, K. M. and Casadei, B. (2005) A myocardial nox2 containing NAD(P)H oxidase contributes to oxidative stress in human atrial fibrillation. Circulation Research, 97(7), pp. 629-636. (doi: 10.1161/01.RES.0000183735.09871.61) (PMID:16123335)

Guzik, T.J. et al. (2005) Superoxide dismutase activity and expression in human venous and arterial bypass graft vessels. Journal of Physiology and Pharmacology, 56(2), pp. 313-323.

Guzik, T.J., Bzowska, M., Kasprowicz, A., Czerniawska-Mysik, G., Wojcik, K., Szmyd, D., Adamek-Guzik, T. and Pryjma, J. (2005) Persistent skin colonization with Staphylococcus aureus in atopic dermatitis: relationship to clinical and immunological parameters. Clinical and Experimental Allergy, 35(4), pp. 448-455. (doi: 10.1111/j.1365-2222.2005.02210.x) (PMID:15836752)

Cichy, M., Adamek-Guzik, T., Uracz, D., Uracz, W., Czerniawska-Mysik, G., Korbut, R. and Guzik, T. J. (2005) [The functional relevance of Arg16Gly and Gln27Glu-beta2-adrenoreceptor polymorphism in patients with asthma and allergic rhinitis]. Folia Medica Cracoviensia, 46(1-2), pp. 33-51. (PMID:17037286)

Guzik, T. J. and Channon, K. M. (2005) Measurement of vascular reactive oxygen species production by chemiluminescence. Methods in Molecular Biology, 108, pp. 73-90. (doi: 10.1385/1-59259-850-1:073) (PMID:16028677)

2004

Cattaruzza, M., Guzik, T. J., Słodowski, W., Pelvan, A., Becker, J., Halle, M., Buchwald, A. B., Channon, K. M. and Hecker, M. (2004) Shear stress insensitivity of endothelial nitric oxide synthase expression as a genetic risk factor for coronary heart disease. Circulation Research, 95(8), pp. 841-847. (doi: 10.1161/01.RES.0000145359.47708.2f) (PMID:15375006)

Guzik, T. J., Sadowski, J., Kapelak, B., Jopek, A., Rudzinski, P., Pillai, R., Korbut, R. and Channon, K. M. (2004) Systemic regulation of vascular NAD(P)H oxidase activity and nox isoform expression in human arteries and veins. Arteriosclerosis, Thrombosis, and Vascular Biology, 24(9), pp. 1614-1620. (doi: 10.1161/01.ATV.0000139011.94634.9d) (PMID:15256399)

Czesnikiewicz-Guzik, M. , Karczewska, E., Bielanski, W., Guzik, T.J., Targosz, A., Konturek, S.J. and Loster, B. (2004) Association of the presence the Helicobacter pylori in the oral cavity and in the stomach. Journal of Physiology and Pharmacology, 55(S2), pp. 105-115.

Pajdak, W., Radwan, J. and Guzik, T.J. (2004) Cleavage of prothrombin bound in immune complexes results in high thrombin enzymatic activity. Journal of Physiology and Pharmacology, 55(2), pp. 477-484. (PMID:15213367)

2003

Guzik, T.J., Korbut, R. and Adamek-Guzik, T. (2003) Nitric oxide and superoxide in inflammation and immune regulation. Journal of Physiology and Pharmacology, 54(4), pp. 469-487. (PMID:14726604)

Mussa, S., Guzik, T. J., Black, E., Dipp, M. A., Channon, K. M. and Taggart, D. P. (2003) Comparative efficacies and durations of action of phenoxybenzamine, verapamil/nitroglycerin solution, and papaverine as topical antispasmodics for radial artery coronary bypass grafting. Journal of Thoracic and Cardiovascular Surgery, 126(6), pp. 1798-1805. (doi: 10.1016/S0022-5223(03)00943-7) (PMID:14688690)

Lucas, A. D., Bursill, C., Guzik, T. J., Sadowski, J., Channon, K. M. and Greaves, D. R., (2003) Smooth muscle cells in human atherosclerotic plaques express the fractalkine receptor CX3CR1 and undergo chemotaxis to the CX3C chemokine fractalkine (CX3CL1). Circulation, 108(20), pp. 2498-2504. (doi: 10.1161/01.CIR.0000097119.57756.EF) (PMID:14581400)

2002

Channon, K.M. and Guzik, T.J. (2002) Mechanisms of superoxide production in human blood vessels: relationship to endothelial dysfunction, clinical and genetic risk factors. Journal of Physiology and Pharmacology, 53(4 Pt 1), pp. 515-524. (PMID:12512689)

Guzik, T.J., Adamek-Guzik, T., Czerniawska-Mysik, G. and Dembinska-Kiec, A. (2002) Nitric oxide metabolite levels in children and adult patients with atopic eczema/dermatitis syndrome. Allergy, 57(9), p. 856. (doi: 10.1034/j.1398-9995.2002.23805.x) (PMID:12169184)

Adamek-Guzik, T., Guzik, T.J., Czerniawska-Mysik, G., Korpanty, G., Mastalerz, L., Radwan, J. and Szczeklik, A. (2002) Urinary leukotriene levels are increased during exacerbation of atopic eczema/dermatitis syndrome. Relation to clinical status. Allergy, 57(8), pp. 732-736. (doi: 10.1034/j.1398-9995.2002.23688.x) (PMID:12121194)

Guzik, T. J., West, N. E.J., Pillai, R., Taggart, D. P. and Channon, K. M. (2002) Nitric oxide modulates superoxide release and peroxynitrite formation in human blood vessels. Hypertension, 39(6), pp. 1088-1094. (doi: 10.1161/01.HYP.0000018041.48432.B5) (PMID:12052847)

Guzik, T. J., Mussa, S., Gastaldi, D., Sadowski, J., Ratnatunga, C., Pillai, R. and Channon, K. M. (2002) Mechanisms of increased vascular superoxide production in human diabetes mellitus: role of NAD(P)H oxidase and endothelial nitric oxide synthase. Circulation, 105(14), pp. 1656-1662. (doi: 10.1161/01.CIR.0000012748.58444.08) (PMID:11940543)

Guzik, T. J., Adamek-Guzik, T., Bzowska, M., Miedzobrodzki, J., Czerniawska-Mysik, G. and Pryjma, J. (2002) [Influence of treating atopic dermatitis with oral antihistamine and topical steroids on selected parameters of cell and humoral immunity]. Folia Medica Cracoviensia, 43(1-2), pp. 79-93. (PMID:12815801)

Ignacak, A., Guzik, T. J., Górski, L., Czerniawska-Mysik, G. and Adamek-Guzik, T. (2002) [Influence of tobacco dust on the respiratory system and selected immunological parameters]. Przeglad Lekarski, 59(10), pp. 789-792. (PMID:12632913)

2001

West, N. E.J., Qian, H., Guzik, T. J., Black, E., Cai, S., George, S. E. and Channon, K. M. (2001) Nitric oxide synthase (nNOS) gene transfer modifies venous bypass graft remodeling: effects on vascular smooth muscle cell differentiation and superoxide production. Circulation, 104(13), pp. 1526-1532. (doi: 10.1161/hc3801.095693) (PMID:11571247)

Black, E. A., Guzik, T. J., West, N. E.J., Campbell, K., Pillai, R., Ratnatunga, C. and Channon, K. M. (2001) Minimally invasive saphenous vein harvesting: effects on endothelial and smooth muscle function. Annals of Thoracic Surgery, 71(5), pp. 1503-1507. (doi: 10.1016/S0003-4975(01)02463-8) (PMID:11383790)

Guzik, T. J., Black, E., West, N. E.J., McDonald, D., Ratnatunga, C., Pillai, R. and Channon, K. M. (2001) Relationship between the G894T polymorphism (Glu298Asp variant) in endothelial nitric oxide synthase and nitric oxide-mediated endothelial function in human atherosclerosis. American Journal of Medical Genetics, 100(2), pp. 130-137. (doi: 10.1002/ajmg.1229) (PMID:11298374)

Adamek-Guzik, T., Guzik, T.J., Bzowska, M., Czerniawska-Mysik, G., Szmyd, D., Miedzobrodzki, J. and Pryjma, J. (2001) [Selected parameters of the cellular and humoral immunity in atopic dermatitis. Relationship to the severity of the disease]. Przeglad Lekarski, 58(12), pp. 1029-1033. (PMID:12041015)

2000

Guzik, T. J., West, N. E.J., Black, E., McDonald, D., Ratnatunga, C., Pillai, R. and Channon, K. M. (2000) Functional effect of the C242T polymorphism in the NAD(P)H oxidase p22phox gene on vascular superoxide production in atherosclerosis. Circulation, 102(15), pp. 1744-1747. (doi: 10.1161/01.CIR.102.15.1744) (PMID:11023926)

Guzik, T. .J., West, N. E.J., Black, E., McDonald, D., Ratnatunga, C., Pillai, R. and Channon, K. M. (2000) Ultrarapid communications: vascular superoxide production by NAD(P)H oxidase: association with endothelial dysfunction and clinical risk factors. Circulation Research, 86(9), p. 1008. (doi: 10.1161/01.RES.86.9.1008) (PMID:10807875)

Guzik, T. J., West, N. E.J., Black, E., McDonald, D., Ratnatunga, C., Pillai, R. and Channon, K. M. (2000) Vascular superoxide production by NAD(P)H oxidase: association with endothelial dysfunction and clinical risk factors. Circulation Research, 86(9), e85-e90. (doi: 10.1161/01.RES.86.9.e85) (PMID:10807876)

This list was generated on Wed Apr 17 22:50:39 2024 BST.

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