This course will give students a detailed understanding of chemical tools used to report on events at specific sites in biological macromolecules.

This course consists of lectures, tutorials, laboratory classes and computer labs.

None

None

A scientific report based on the laboratory practical (100%)

This course aims to provide students with the opportunity to develop their knowledge of and gain experience with biophysical techniques and chemical biology tools used for exploring biological macromolecules and their interactions with ligands.

By the end of this course students should be able to:

■ Critically discuss how molecular motion and interactions can be measured using fluorescence or NMR spectroscopy

■ Evaluate and justify a choice of chemical tool to use as a fluorescent or spectroscopic probe of biomolecular motion or interactions

■ Collect, analyse, and critically interpret their own data acquired using one or more of these techniques

■ Communicate effectively their own data in a suitable scientific format.

Students must submit at least 75% by weight of the components (including examinations) of the course's summative assessment.