Prof Paul Horgan
- Professor (Surgery)
- Associate Academic (Institute of Cancer Sciences)
telephone: 01413308046
email: Paul.Horgan@glasgow.ac.uk
2012
Dutta, S., Going, J.J. , Crumley, A.B.C, Mohammed, Z. , Orange, C. , Edwards, J. , Fullarton, G.M. , Horgan, P.G. , and McMillan, D.C. (2012) The relationship between tumour necrosis, tumour proliferation, local and systemic inflammation, microvessel density and survival in patients undergoing potentially curative resection of oesophageal adenocarcinoma. British Journal of Cancer, 106 (4). pp. 702-710. ISSN 0007-0920 (doi:10.1038/bjc.2011.610)
Nicholson, G.A., Morrison, D.S. , Finlay, I.G., Diament, R.H., Horgan, P.G. , and Molloy, R.G. (2012) Quality of care in rectal cancer surgery. Exploring influencing factors in the West of Scotland. Colorectal Disease . ISSN 1462-8910 (doi:10.1111/j.1463-1318.2011.02754.x) (In Press)
Powell, A.G., Wallace, R., McKee, R.F. , Anderson, J.H. , Going, J.J. , Edwards, J. , and Horgan, P.G. (2012) The relationship between tumour site, clinicopathological characteristics and cancer-specific survival in patients undergoing surgery for colorectal cancer. Colorectal Disease . ISSN 1462-8910 (doi:10.1111/j.1463-1318.2012.03048.x) (In Press)
Powell, A.G.M.T., Edwards, J. , and Horgan, P.G. (2012) A move towards individualisation of patient treatment regimens in colorectal cancer. Colorectal Disease . ISSN 1463-1318 (doi:10.1111/j.1463-1318.2011.02818.x) (In Press)
Powell, A.G.M.T., Edwards, J. , and Horgan, P.G. (2012) A move towards individualization of patient treatment regimens in colorectal cancer. Colorectal Disease, 14 (2). pp. 255-256. ISSN 1462-8910 (doi:10.1111/j.1463-1318.2011.02818.x)
Powell, A.G.M.T., Horgan, P.G. , and Edwards, J. (2012) The bodies fight against cancer: is human leucocyte antigen (HLA) class 1 the key? Journal of Cancer Research and Clinical Oncology, 138 (5). pp. 723-728. ISSN 0171-5216 (doi:10.1007/s00432-012-1192-4)
Qayyum, T. et al. (2012) The interrelationships between Src, Cav-1 and RhoGD12 in transitional cell carcinoma of the bladder. British Journal of Cancer, 106 (6). pp. 1187-1195. ISSN 0007-0920 (doi:10.1038/bjc.2012.52)
Roxburgh, C.S.D., Richards, C.H. , Moug, S.J., Foulis, A.K. , McMillan, D.C. , and Horgan, P.G. (2012) Determinants of short- and long-term outcome in patients undergoing simultaneous resection of colorectal cancer and synchronous colorectal liver metastases. International Journal of Colorectal Disease, 27 (3). pp. 363-369. ISSN 0179-1958 (doi:10.1007/s00384-011-1339-9)
2011
Proctor, M.J., Morrison, D.S. , Talwar, D., Balmer, S.M., Fletcher, C.D., O’Reilly, D.St.J., Foulis, A.K. , Horgan, P.G. , and McMillan, D.C. (2011) A comparison of inflammation-based prognostic scores in patients with cancer. A Glasgow Inflammation Outcome Study. European Journal of Cancer, 47 (17). pp. 2633-2641. ISSN 0959-8049 (doi:10.1016/j.ejca.2011.03.028)
Maxwell, F., McGlynn, L.M. , Muir, H.C., Talwar, D., Benzeval, M. , Robertson, T., Roxburgh, C.S. , McMillan, D. , Horgan, P.G. , and Shiels, P. (2011) Telomere attrition and decreased Fetuin A levels indicate accelerated biological ageing and are implicated in the pathogenesis of colorectal cancer. Clinical Cancer Research, 17 (17). pp. 5573-5581. ISSN 1078-0432 (doi:10.1158/1078-0432.CCR-10-3271)
Maxwell, F., McGlynn, L.M. , Muir, H.C., Talwar, D., Benzeval, M. , Robertson, T., Roxburgh, C.S. , McMillan, D.C. , Horgan, P.G. , and Shiels, P.G. (2011) Telomere attrition and decreased fetuin-A levels indicate accelerated biological aging and are implicated in the pathogenesis of colorectal cancer. Clinical Cancer Research, 17 (17). pp. 5573-5581. ISSN 1078-0432 (doi:10.1158/1078-0432.CCR-10-3271)
Dutta, S., Crumley, A.B.C., Fullarton, G.M. , Horgan, P. , and McMillan, D. (2011) Comparison of the prognostic value of tumour- and patient-related factors in patients undergoing potentially curative resection of oesophageal cancer. World Journal of Surgery, 35 (8). pp. 1861-1866. ISSN 0364-2313 (doi:10.1007/s00268-011-1130-7)
Nicholson, G. A., Finlay, I. G., Diament, R. H., Molloy, R. G., Horgan, P.G. , and Morrison, D. S. (2011) Mechanical bowel preparation does not influence outcomes following colonic cancer resection. British Journal of Surgery, 98 (6). pp. 866-871. ISSN 0007-1323 (doi:10.1002/bjs.7454)
Roxburgh, C., McDonald, A., Salmond, J. , Oien, K. , Anderson, J. , McKee, R. , Horgan, P. , and McMillan, D. (2011) Adjuvant chemotherapy for resected colon cancer: comparison of the prognostic value of tumour and patient related factors. International Journal of Colorectal Disease, 26 (4). pp. 483-492. ISSN 0179-1958 (doi:10.1007/s00384-010-1120-5)
Roxburgh, C.S.D., Platt, J.J., Leitch, E.F., Kinsella, J. , Horgan, P.G. , and McMillan, D.C. (2011) Relationship between preoperative comorbidity, systemic inflammatory response, and survival in patients undergoing curative resection for colorectal cancer. Annals of Surgical Oncology, 18 (4). pp. 997-1005. ISSN 1068-9265 (doi:10.1245/s10434-010-1410-8)
Dutta, S., Fullarton, G.M. , Forshaw, M.J. , Horgan, P.G. , and McMillan, D.C. (2011) Persistent Elevation of C-Reactive Protein Following Esophagogastric Cancer Resection as a Predictor of Postoperative Surgical Site Infectious Complications. World Journal of Surgery, 35 (5). pp. 1017-1025. ISSN 0364-2313 (doi:10.1007/s00268-011-1002-1)
Dutta, S., Al-Mrabt, N.M., Fullarton, G.M. , Horgan, P.G. , and McMillan, D.C. (2011) A comparison of POSSUM and GPS models in the prediction of post-operative outcome in patients undergoing oesophago-gastric cancer resection. Annals of Surgical Oncology, 18 (10). pp. 2808-2817. ISSN 1068-9265 (doi:10.1245/s10434-011-1676-5)
Proctor, M.J., Morrison, D.S. , Talwar, D., Balmer, S.M., O'Reilly, D.S.J. , Foulis, A.K. , Horgan, P.G. , and McMillan, D.C. (2011) An inflammation-based prognostic score (mGPS) predicts cancer survival independent of tumour site: a Glasgow Inflammation Outcome Study. British Journal of Cancer, 104 (4). pp. 726-734. ISSN 0007-0920 (doi:10.1038/sj.bjc.6606087)
Richards, C.H., Platt, J.J. , Anderson, J.H. , McKee, R.F. , Horgan, P.G. , and McMillan, D.C. (2011) The Impact of Perioperative Risk, Tumor Pathology and Surgical Complications on Disease Recurrence After Potentially Curative Resection of Colorectal Cancer. Annals of Surgery, 254 (1). pp. 83-89. ISSN 0003-4932 (doi:10.1097/SLA.0b013e31821fd469)
Richards, C.H., Leitch, E.F., Anderson, J.H. , McKee, R.F. , McMillan, D.C. , and Horgan, P.G. (2011) The revised ACPGBI model is a simple and accurate predictor of operative mortality after potentially curative resection of colorectal cancer. Annals of Surgical Oncology, 18 (13). pp. 3680-3685. ISSN 1068-9265 (doi:10.1245/s10434-011-1805-1)
2010
Roxburgh, C.S.D., McMillan, D.C. , Anderson, J.H. , McKee, R.F. , Horgan, P.G. , and Foulis, A.K. (2010) Elastica staining for venous invasion results in superior prediction of cancer specific survival in colorectal cancer. Annals of Surgery, 252 (6). pp. 989-997. ISSN 0003-4932 (doi:10.1097/SLA.0b013e3181f1c60d)
Roxburgh, C.S.D., Wallace, A.M., Guthrie, G., Horgan, P.G. , and McMillan, D.C. (2010) Comparison of the prognostic value of tumour and patient related factors in patients undergoing potentially curative surgery for colon cancer. Colorectal Disease, 12 (10). pp. 987-994. ISSN 1462-8910 (doi:10.1111/j.1463-1318.2009.01961.x)
Dutta, S., Horgan, P.G. , and McMillan, D.C. (2010) POSSUM and its related models as predictors of postoperative mortality and morbidity in patients undergoing surgery for gastro-oesophageal cancer: a systematic review. World Journal of Surgery, 34 (9). pp. 2076-2082. ISSN 0364-2313 (doi:10.1007/s00268-010-0685-z)
Horgan, P.G., and McMillan, D.C. (2010) Surgeons and selection of adjuvant therapy for node-negative colonic cancer. British Journal of Surgery, 97 (10). pp. 1459-1460. ISSN 0007-1323 (doi:10.1002/bjs.7254)
Leung, E. Y. L., Roxburgh, C. S. D. , Leen, E., and Horgan, P. G. (2010) Combined resection and radiofrequency ablation for bilobar colorectal cancer liver metastases. Hepato-Gastroenterology, 57 (97). pp. 41-46. ISSN 0172-6390
Moug, S. J., Smith, D., Leen, E., Roxburgh, C. , and Horgan, P. G. (2010) Evidence for a synchronous operative approach in the treatment of colorectal cancer with hepatic metastases: A case matched study. Ejso, 36 (4). pp. 365-370. ISSN 0748-7983 (doi:10.1016/j.ejso.2009.11.007)
Proctor, M J, Talwar, D, Balmar, S M, O'Reilly, D S J , Foulis, A K , Horgan, P.G. , Morrison, D S , and McMillan, D C (2010) The relationship between the presence and site of cancer, an inflammation-based prognostic score and biochemical parameters. Initial results of the Glasgow Inflammation Outcome Study. British Journal of Cancer, 103 (6). pp. 870-876. ISSN 0007-0920 (doi:10.1038/sj.bjc.6605855)
Richards, C.H., Leitch, E.F., Horgan, P.G. , Anderson, J., McKee, R.F. , and McMillan, D.C. (2010) The relationship between patient physiology, the systemic inflammatory response and survival in patients undergoing curative resection of colorectal cancer. British Journal of Cancer, 103 (9). pp. 1356-1361. ISSN 0007-0920 (doi:10.1038/sj.bjc.6605919)
Richards, C.H., Leitch, F.E., Horgan, P.G. , and McMillan, D.C. (2010) A Systematic Review of POSSUM and its Related Models as Predictors of Post-operative Mortality and Morbidity in Patients Undergoing Surgery for Colorectal Cancer. Journal of Gastrointestinal Surgery, 14 (10). pp. 1511-1519. ISSN 1091-255X (doi:10.1007/s11605-010-1333-5)
2009
Roxburgh, C.S., Salmond, J.M., Horgan, P.G. , Oien, K.A. , and McMillan, D.C. (2009) Tumour inflammatory infiltrate predicts survival following curative resection for node-negative colorectal cancer. European Journal of Cancer, 45 (12). pp. 2138-2145. ISSN 0959-8049 (doi:10.1016/j.ejca.2009.04.011)
Roxburgh, C.S.D., Salmond, J.M., Horgan, P.G. , Oien, K.A. , and McMillan, D.C. (2009) Comparison of the prognostic value of inflammation based pathological and biochemical criteria in patients undergoing potentially curative resection for colorectal cancer. Annals of Surgery, 249 (5). pp. 788-793. ISSN 0003-4932 (doi:10.1097/SLA.0b013e3181a3e738)
Roxburgh, C.S.D., Salmond, J.M. , Horgan, P.G. , Oien, K.A. , and McMillan, D.C. (2009) The relationship between the local and systemic inflammatory responses and survival in patients undergoing curative surgery for colon and rectal cancers. Journal of Gastrointestinal Surgery, 13 (11). pp. 2011-2019. ISSN 1091-255X (doi:10.1007/s11605-009-1034-0)
Roxburgh, C.S.D., Wallace, A.M. , Guthrie, G. K., Horgan, P. G. , and McMillan, D. C. (2009) Comparison of the prognostic value of tumour- and patient-related factors in patients undergoing potentially curative surgery for colon cancer. Colorectal Disease, 12 (10). pp. 987-994. ISSN 14628910 (doi:10.1111/j.1463-1318.2009.01961.x)
2008
Leung, E.Y.L., Roxburgh, C.S.D. , Leen, E., and Horgan, P.G. (2008) Combined resection and radiofrequency ablation for bilobar liver metastases. European Journal of Surgical Oncology, 34 (10). p. 1168. ISSN 0748-7983 (doi:10.1016/j.ejso.2008.06.062)
2007
Crozier, J.E., McMillan, D.C. , McArdle, C.S., Angerson, W.J. , Anderson, J.H., Horgan, P. , and McKee, R.F. (2007) Tumor size is associated with the systemic inflammatory response but not survival in patients with primary operable colorectal cancer. Journal of Gastroenterology and Hepatology, 22 (12). pp. 2288-2291. ISSN 0815-9319 (doi:10.1111/j.1440-1746.2006.04792.x)
Crozier, J.E.M., McKee, R.F. , McArdle, C.S., Angerson, W.J. , Anderson, J.H. , Horgan, P. , and McMillan, D.C. (2007) Preoperative but not postoperative systemic inflammatory response correlates with survival in colorectal cancer. British Journal of Surgery, 94 (8). pp. 1028-1032. ISSN 0007-1323 (doi:10.1002/bjs.5706)
Ceccotti, PC, Horgan, P , Leen, E, and Moug, S (2007) Contrast-enhanced intraoperative ultrasonography: A valuable and not any more monocentric diagnostic technique performed in different ways - Reply. Annals of Surgery, 245 (1). pp. 152-153. ISSN 0003-4932 (doi:10.1097/00000658-200701000-00024)
Horgan, P (2007) Metastatic colorectal cancer. Surgical Oncology-oxford, 16 (1). p. 1.
Horgan, P (2007) Selective continuous vascular occlusion and perioperative fluid restriction in partial hepatectomy. Outcomes in 101 consecutive patients. European Journal of Surgical Oncology, 33 (8). pp. 1036-1041. ISSN 0748-7983 (doi:10.1016/j.ejso.2007.01.028)
Horgan, PG, and Leen, E (2007) Radiofrequency ablation of colorectal liver metastases. Surgical Oncology-oxford, 16 . pp. 47-51. (doi:10.1016/j.suronc.2007.04.004)
Horgan, PG, and Moug, SJ (2007) The role of synchronous procedures in the treatment of colorectal liver metastases. Surgical Oncology-oxford, 16 . pp. 53-58. (doi:10.1016/j.suronc.2007.04.005)
Leitch, E.F., Chakrabarti, M., Crozier, J.E.M., McKee, R.F. , Anderson, J.H. , Horgan, P. , and McMillan, D.C. (2007) Comparison of the prognostic value of selected markers of the systemic inflammatory response in patients with colorectal cancer. British Journal of Cancer, 97 (9). pp. 1266-1270. ISSN 0007-0920
Moug, SJ, Smith, D, Leen, E, Angerson, WJ , and Horgan, P (2007) Selective continuous vascular occlusion and perioperative fluid restriction in partial hepatectomy. Outcomes in 101 consecutive patients. Ejso, 33 (8). pp. 1036-1041.
2006
Alani, A, Duffy, F, Horgan, P , Norrie, J, O'Dwyer, PJ , and Walker, A (2006) Observation or operation for patients with an asymptomatic inguinal hernia - A randomized clinical trial. Annals of Surgery, 244 . pp. 167-173. ISSN 0003-4932 (doi:10.1097/01.sla.0000217637.69699.ef)
Ceccotti, PC, Horgan, P , Kalogeropoulou, CP, and Leen, E (2006) Is contrast enhanced ultrasound an essential tool for liver trauma? Journal of Trauma-injury Infection and Critical Care, 60 . pp. 233-236. (doi:10.1097/01.ta.0000200843.80420.28)
Crozier, J., McKee, R. , McArdle, C., Angerson, W. , Anderson, J. , Horgan, P. , and McMillan, D. (2006) The presence of a systemic inflammatory response predicts poorer survival in patients receiving adjuvant 5-FU chemotherapy following potentially curative resection for colorectal cancer. British Journal of Cancer, 94 . pp. 1833-1836. ISSN 0007-0920 (doi:10.1038/sj.bjc.6603185)
Horgan, P (2006) Potential value of contrast-enhanced intraoperative ultrasonography during partial hepatectomy for metastases: an essential investigation before resection? Annals of Surgery, 243 (2). pp. 236-240. ISSN 0003-4932 (doi:10.1097/01.sla.0000197708.77063.07)
Horgan, P (2006) The renal sequelae of a novel triphasic approach to blood loss reduction during hepatic resection. European Journal of Surgical Oncology, 32 (4). pp. 435-438. (doi:10.1016/j.ejso.2006.01.011)
Horgan, P, Leen, E, Moug, SJ, Smith, D, and Wilson, IS (2006) The renal sequelae of a novel triphasic approach to blood loss reduction during hepatic resection. Ejso, 32 (4). pp. 435-438.
Horgan, PG, Imrie, CW, Leen, E, and Moug, SJ (2006) Radiofrequency ablation has a valuable therapeutic role in metastatic VIPoma. Pancreatology, 6 . pp. 155-159. (doi:10.1159/000090257)
Leen, E, Ceccotti, P, Kalogeropoulou, C, Angerson, WJ , Moug, SJ, and Horgan, PG (2006) Prospective multicenter trial evaluating a novel method of characterizing focal liver lesions using contrast-enhanced sonography. American Journal of Roentgenology, 186 . pp. 1551-1559. (doi:10.2214/AJR.05.0138)
Leen, E et al. (2006) Potential value of contrast-enhanced intraoperative ultrasonography during partial hepatectomy for metastases - An essential investigation before resection? Annals of Surgery, 243 (2). pp. 236-240. ISSN 0003-4932
2005
Anderson, JH et al. (2005) Accuracy of thin section magnetic resonance using phased-array pelvic coil in predicting the T-staging of rectal cancer. European Journal of Radiology, 53 (2). pp. 256-262.
Craig, SR, Horgan, P , Moug, SJ, and Roditi, G (2005) Hepatobiliary and pancreatic: Extensive thrombosis in Budd-Chiari syndrome. Journal of Gastroenterology and Hepatology, 20 (8). p. 1302.
Hallum, N, Horgan, P , Moug, SJ, and O'Reilly, DS (2005) Cardiac troponin I predicts outcome after ruptured abdominal aortic aneurysm repair (Br J Surg 2005; 92 : 824-827). British Journal of Surgery, 92 (11). p. 1454.
Moug, SJ, Robertson, E, Angerson, WJ , and Horgan, P (2005) Socioeconomic deprivation has an adverse effect on outcome after ileostomy closure. British Journal of Surgery, 92 (3). pp. 376-377.
2004
Al, SR, Angerson, WJ , Horgan, P , McArdle, CS, and McMillan, DC (2004) The relationship between hypoalbuminaemia, tumour volume and the systemic inflammatory response in patients with colorectal liver metastases. British Journal of Cancer, 91 . pp. 205-207. (doi:10.1038/sj.bjc.6601886)
Canna, K, Horgan, PG , McArdle, CS, McKee, RF, McMillan, DC , and McNicol, AM (2004) Evaluation of a cumulative prognostic score based on the systemic inflammatory response in patients undergoing potentially curative surgery for colorectal cancer. British Journal of Cancer, 90 . pp. 1707-1709. (doi:10.1038/sj.bjc.6601757)
Horgan, P (2004) Contrast-enhanced ultrasonography during liver surgery (Br J Surg 2004; 91: 1165-1167). British Journal of Surgery, 91 (11). p. 1527. (doi:10.1002/bjs.4852)
Horgan, P, Leen, E, and Moug, SJ (2004) Contrast-enhanced ultrasonography during liver surgery (Br J Surg 2004; 91 : 1165-1167). British Journal of Surgery, 91 (11). p. 1527.
Horgan, P, Leen, E, and Moug, SJ (2004) Potential impact and utilization of ultrasound contrast media. European Radiology, 14 . P16-P24. (doi:10.1007/s10406-004-0077-2)
2003
O'Dwyer, P.J. et al. (2003) Local or general anesthesia for open hernia repair: a randomized trial. Annals of Surgery, 237 (4). pp. 574-579. ISSN 0003-4932
Franklin, EJ, Horgan, P , Lowney, J, and Seetharam, S (2003) Randomized, clinical trial of Ligasure (TM) vs. conventional diathermy in hemorrhoidectomy. Diseases of the Colon and Rectum, 46 (10). pp. 1380-1383. ISSN 0012-3706
Glen, P, and Horgan, P (2003) A simple technique for fenestration of an hepatic cyst. Annals of the Royal College of Surgeons of England, 85 (3). p. 209.
Horgan, PG, Paige, J, and Seetharam, S (2003) Impact of socioeconomic deprivation and primary pathology on rate of reversal of Hartmann's procedure. American Journal of Surgery, 186 . pp. 154-157. (doi:10.1016/S0002-9610(03)00172-7)
2002
Horgan, P (2002) The 'half-Pringle' maneuver - Reply. American Journal of Surgery, 184 (2). pp. 182-183.
Horgan, P, Kenny, GNC, and Milne, SE (2002) Target-controlled infusions of propofol and remifentanil with closed-loop anaesthesia for hepatic resection. Anaesthesia, 57 (1). p. 93.
2001
Horgan, P (2001) A novel technique for parenchymal division during hepatectomy. American Journal of Surgery, 181 (3). pp. 236-237.
Horgan, P (2001) A simple technique for vascular control during hepatectomy: the half-Pringle. American Journal of Surgery, 182 (3). pp. 265-267. ISSN 0002-9610 (doi:10.1016/S0002-9610(01)00697-3)
Horgan, P, and Leen, E (2001) A simple technique for vascular control during hepatectomy: the half-Pringle. American Journal of Surgery, 182 (3). pp. 265-267.
Horgan, P, and Quasim, T (2001) Severe abdominal pain in women: A case report of an hepatic adenoma. Scottish Medical Journal, 46 . p. 147.
- Clinical Research Fellows - Greater Glasgow
NHS Greater Glasgow and Clyde
2010 - 2013
- Clinical Research Fellows - Golden Jubilee
Golden Jubilee Hospital
2009 - 2013
- Effect of intravenous fluids and sodium restriction on patient recovery following major abdominal surgery - a single blind pragmatic randomised clinical trial.
North Glasgow University Hospitals NHS Trust
2005 - 2005
- Effect of intravenous fluids and sodium restriction on patient recovery following major abdominal surgery - a single blind pragmatic randomised clinical trial.
Scottish Executive Health Department
2003 - 2005
