Professor Christian Delles
- Professor, Head of School, Cardiovascular & Metabolic Health (Cardiovascular & Metabolic Health)
telephone:
3302749
email:
Christian.Delles@glasgow.ac.uk
Room 421, School of Cardiovascular & Metabolic Health, BHF GCRC, 126 University Place, Glasgow, G128TA
Personal assistant: Mrs Margaret Kinninmont
telephone: 01413307774
email: Margaret.Kinninmont@glasgow.ac.uk
Biography
Christian Delles is Professor of Cardiovascular Prevention; Head of the School of Cardiovascular and Metabolic Health, University of Glasgow; and Honorary Consultant Physician with NHS Greater Glasgow & Clyde. His research focusses on prevention of cardiovascular diseases and spans from fundamental mechanistic research to clinical translation. Much of his research is driven by an interest in hypertension and includes the molecular basis of vascular diseases; the pathogenesis and long-term consequences of hypertension including hypertensive disorders of pregnancy and gestational diabetes; links between cardiovascular and renal diseases; and differences in the pathophysiology of cardiovascular diseases between men and women. Prof. Delles serves as Secretary of the Council of the European Society of Hypertension, Chair of Scottish Heart & Arterial disease Risk Prevention (SHARP), Honorary Treasurer of the Association of Physicians of Great Britain and Ireland, and Treasurer of the European Council for Cardiovascular Research. He is a member of national and international grant panels and associate editor and editorial board member of leading cardiovascular journals. He has a keen interest in teaching and training and chairs the University's Clinical Academic Training Advisory Committee.
Research interests
Research Theme: Vascular Diseases and Comorbidities
Christian’s research focusses on prevention of cardiovascular diseases and spans from fundamental mechanistic research to clinical translation. Much of his research is driven by an interest in hypertension and includes the molecular basis of vascular diseases; the pathogenesis and long-term consequences of hypertension including hypertensive disorders of pregnancy and gestational diabetes; links between cardiovascular and renal diseases; and differences in the pathophysiology of cardiovascular diseases between men and women. Prof. Delles serves as member of the Council of the European Society of Hypertension, Honorary Treasurer of the Association of Physicians of Great Britain and Ireland Treasurer of the European Council for Cardiovascular Research, and Chair of SHARP. He is a member of national and international grant panels and associate editor and editorial board member of leading cardiovascular journals.
Research groups
Publications
2024
Greenlees, C., Hosseinzadeh, S., Delles, C. and Mcginnigle, E. (2024) Hypertension evaluation and management in new young patients: are we doing our female patients a disservice? Blood Pressure, 33(1), 2387909. (doi: 10.1080/08037051.2024.2387909) (PMID:39102372)
Dieden, A. et al. (2024) Proteomic biomarkers and pathway analysis for progression to heart failure in three epidemiological representative cohorts. European Journal of Heart Failure, (doi: 10.1002/ejhf.3502) (PMID:39466935) (Early Online Publication)
Dieden, A. et al. (2024) Proteomic biomarkers and pathway analysis for progression to heart failure in three epidemiological representative cohorts. European Journal of Heart Failure, (Accepted for Publication)
Ho, F. et al. (2024) Maternal and pregnancy factors contributing to the association between area deprivation and infant mortality in England: a retrospective cohort study. Lancet Regional Health Europe, (doi: 10.1016/j.lanepe.2024.101075) (In Press)
Zhou, M., Mary, S. , Delles, C. , Padmanabhan, S. , Graham, D. , McBride, M. W. and Dominiczak, A. (2024) Insights into uromodulin and blood pressure. Current Hypertension Reports, (doi: 10.1007/s11906-024-01317-0) (PMID:39259220) (Early Online Publication)
Delles, C. , Setjiadi, D. and Geddes, C. (2024) Blood pressure measurement technique in clinical practice. Research Square, (doi: 10.21203/rs.3.rs-4635130/v1)
Kulkarni, S. et al. (2024) Investigation and management of young-onset hypertension: British and Irish Hypertension Society position statement. Journal of Human Hypertension, (doi: 10.1038/s41371-024-00922-5) (PMID:38942895) (Early Online Publication)
Padmanabhan, S. , Delles, C. and Dominiczak, A. F. (2024) Beyond genome-wide scans: advancing hypertension genomics into the future. Hypertension, 81(6), pp. 1186-1189. (doi: 10.1161/HYPERTENSIONAHA.124.21371) (PMID:38748763)
Docherty, N. G., Delles, C. and López-Hernández, F. J. (2024) Reframing acute kidney injury as a pathophysiological continuum of disrupted renal excretory function. Acta Physiologica, (doi: 10.1111/apha.14181) (PMID:38808913) (Early Online Publication)
Kobayashi, M. et al. (2024) Proteomic profiles of left atrial volume and its influence on response to spironolactone: findings from the HOMAGE trial and STANISLAS cohort. European Journal of Heart Failure, 26(5), pp. 1231-1241. (doi: 10.1002/ejhf.3202) (PMID:38528728)
Lim, M. W. S., Lucas-Herald, A. K. , Mason, A., Delles, C. and Connelly, P. J. (2024) Sex differences in the cardiovascular effects of GnRH analogues. Journal of Endocrinology, 261(1), e230309. (doi: 10.1530/JOE-23-0309) (PMID:38265843)
Rossitto, G., Bertoldi, G., Rutkowski, J. M., Mitchell, B. M. and Delles, C. (2024) Sodium, interstitium, lymphatics, and hypertension - A tale of hydraulics. Hypertension, 81(4), pp. 727-737. (doi: 10.1161/HYPERTENSIONAHA.123.17942) (PMID:38385255)
Sani, R. N., Connelly, P. J. , Toft, M., Rowa-Dewar, N., Delles, C. , Gasevic, D. and Karaye, K. M. (2024) Rural-urban difference in the prevalence of hypertension in West Africa: a systematic review and meta-analysis. Journal of Human Hypertension, 38, pp. 352-364. (doi: 10.1038/s41371-022-00688-8) (PMID:35430612) (PMCID:PMC11001577)
Mavrogeorgis, E. et al. (2024) Multiple urinary peptides are associated with hypertension: a link to molecular pathophysiology. Journal of Hypertension, (doi: 10.1097/HJH.0000000000003726) (PMID:38690919) (Early Online Publication)
Setjiadi, D., Delles, C. , Boutouyrie, P. and Bruno, R. M. (2024) Inappropriate Pulse Wave Velocity to Blood Pressure Level: Definition and Clinical Determinants. 26th Meeting of the European Council for Cardiovascular Research, Online, 24-25 Nov 2023. A1-A42.
Bosserdt, M. et al. (2024) Age and computed tomography and invasive coronary angiography in stable chest pain: a prespecified secondary analysis of the discharge randomized clinical trial. JAMA Cardiology, 9(4), pp. 346-356. (doi: 10.1001/jamacardio.2024.0001) (PMID:38416472)
Olowoyo, P. et al. (2024) Priorities to reduce the burden of hypertension in Africa through ACHIEVE. Lancet Global Health, 12(2), e192-e193. (doi: 10.1016/S2214-109X(23)00540-5) (PMID:38245107)
Mary, S. et al. (2024) Pregnancy-associated changes in urinary uromodulin excretion in chronic hypertension. Journal of Nephrology, (doi: 10.1007/s40620-023-01830-6) (PMID:38236469) (Early Online Publication)
Kharlamov, A., Sherriff, N., Delles, C. and van der Harst, P. (2024) Tackling cardiovascular healthcare disparities for LGBTQIA+ population: a call to action in the European Society of Cardiology. European Heart Journal, (doi: 10.1093/eurheartj/ehad882) (PMID:38195053) (Early Online Publication)
2023
Bagordo, D., Rossi, G. P., Delles, C. , Wiig, H. and Rossitto, G. (2023) The tangram of sodium and fluid balance: salt series. Hypertension, (doi: 10.1161/HYPERTENSIONAHA.123.19569) (Early Online Publication)
Neupane, D. et al. (2023) Emerging Authors Program for building cardiovascular disease prevention and management research capacity in low- and middle-income countries: a collaboration of the U.S. Centers for Disease Control and Prevention, the Lancet Commission on Hypertension Group, Resolve to Save Lives, and the World Hypertension League. Journal of Human Hypertension, -023. (doi: 10.1038/s41371-023-00880-4) (Early Online Publication)
Connelly, P. , Osmanska, J., Lee, M. M.Y. , Delles, C. , McEntegart, M. B. and Byrne, J. (2023) A case report of myocardial infarction in a young transgender man with testosterone therapy? raising awareness on healthcare issues in the transgender community and a call for further research. European Heart Journal: Case Reports, 7(12), ytad562. (doi: 10.1093/ehjcr/ytad562) (PMID:38093823) (PMCID:PMC10716680)
Desson, Z. et al. (2023) Improving the accuracy of blood pressure measuring devices in Australia: a modelled return on investment study. Journal of Human Hypertension, (doi: 10.1038/s41371-023-00866-2) (PMID:37938294) (Early Online Publication)
Murphy, C. N., Delles, C. , Davies, E. and Connelly, P. J. (2023) Cardiovascular disease in transgender individuals. Atherosclerosis, 384, 117282. (doi: 10.1016/j.atherosclerosis.2023.117282) (PMID:37821271)
de Beer, D., MC. Mels, C., Schutte, A., Delles, C. , Mary, S. , Mullen, W. , Mischak, H. and Kruger, R. (2023) Urinary peptidomics and pulse wave velocity: The African-PREDICT study. Journal of Proteome Research, 22(10), pp. 3282-3289. (doi: 10.1021/acs.jproteome.3c00347) (PMID:37688558) (PMCID:PMC10563154)
Mangion, K. et al. (2023) Post-COVID-19 illness and associations with sex and gender. BMC Cardiovascular Disorders, 23, 389. (doi: 10.1186/s12872-023-03412-7) (PMID:37553628) (PMCID:PMC10408208)
Brown, C. E., Casey, H., Dominiczak, A. F. , Kerr, S., Campbell, A. and Delles, C. (2023) Impact of preeclampsia on cardiovascular events: an analysis of the Generation Scotland: Scottish family health study. Journal of Human Hypertension, 37(8), pp. 735-741. (doi: 10.1038/s41371-023-00812-2) (PMID:36973315)
Casey, H., Dennehy, N., Fraser, A., Lees, C., McEniery, C. M., Scott, K. , Wilkinson, I. B. and Delles, C. (2023) Placental syndromes and maternal cardiovascular health. Clinical Science, 137(16), pp. 1211-1224. (doi: 10.1042/CS20211130) (PMID:37606085)
Connelly, P. J. and Delles, C. (2023) Journal of Human Hypertension special issue on sex and gender differences in hypertension. Journal of Human Hypertension, 37(8), pp. 587-588. (doi: 10.1038/s41371-023-00847-5) (PMID:37474602)
Angelov, A., Connelly, P. J. , Delles, C. and Kararigas, G. (2023) Sex-biased and sex hormone-dependent regulation of apolipoprotein A1. Current Opinion in Physiology, 33, 100654. (doi: 10.1016/j.cophys.2023.100654)
De Beer, D., Mels, C. M.C., Schutte, A. E., Delles, C. , Mary, S. , Mullen, W. , Latosinska, A., Mischak, H. and Kruger, R. (2023) Identifying a urinary peptidomics profile for hypertension in young adults: the African-PREDICT study. Proteomics, 23(11), 2200444. (doi: 10.1002/pmic.202200444) (PMID:36943111)
Arisido, M. W. et al. (2023) Cluster analysis of angiotensin biomarkers to identify antihypertensive drug treatment in population studies. BMC Medical Research Methodology, 23, 131. (doi: 10.1186/s12874-023-01930-8) (PMID:37245005) (PMCID:PMC10224304)
Girerd, N. et al. (2023) Protein biomarkers of new-onset heart failure: insights from the Heart Omics and Ageing cohort, the Atherosclerosis Risk in Communities Study, and the Framingham Heart Study. Circulation: Heart Failure, 16(5), pp. 426-441. (doi: 10.1161/CIRCHEARTFAILURE.122.009694) (PMID:37192292) (PMCID:PMC10179982)
Wang, Y. et al. (2023) Early-life cardiovascular risk factor trajectories and vascular aging in midlife: a 30-year prospective cohort study. Hypertension, 80(5), pp. 1057-1066. (doi: 10.1161/HYPERTENSIONAHA.122.20518) (PMID:36880389)
Degenaar, A., Jacobs, A., Kruger, R., Delles, C. , Mischak, H. and Mels, C.M.C. (2023) Cardiovascular risk and kidney function profiling using conventional and novel biomarkers in young adults: the African-PREDICT study. BMC Nephrology, 24, 96. (doi: 10.1186/s12882-023-03100-w) (PMID:37055746) (PMCID:PMC10103421)
Edgar, B. et al. (2023) The impact of renal artery stenting on therapeutic aims. Journal of Human Hypertension, 37(4), pp. 265-272. (doi: 10.1038/s41371-022-00785-8) (PMID:36526895) (PMCID:PMC10063438)
Rotbain Curovic, V. et al. (2023) Presence of retinopathy and incident kidney and cardiovascular events in type 2 diabetes with normoalbuminuria – a post-hoc analysis of the PRIORITY randomized clinical trial. Journal of Diabetes and its Complications, 37(4), 108433. (doi: 10.1016/j.jdiacomp.2023.108433) (PMID:36841085)
Setjiadi, D., Delles, C. , Currie, G. and Celis-Morales, C. A. (2023) Relationship between blood pressure level and hypertensive mediated organ damage. The 26th Annual Meeting of the Scottish Cardiovascular Forum, Aberdeen, UK, 04 Feb 2023. A2.1-A2. (doi: 10.1136/heartjnl-SCF-2023.4)
Kimera, I. D. et al. (2023) Integrated multi-month dispensing of antihypertensive and antiretroviral therapy to sustain hypertension and HIV control. Journal of Human Hypertension, 37(3), pp. 213-219. (doi: 10.1038/s41371-022-00655-3) (PMID:35246602) (PMCID:PMC8896410)
Picone, D. S., Peterson, G. M., Jackson, S. L., Campbell, N. R.C., Delles, C. , Olsen, M. H., Padwal, R., Schutte, A. E. and Sharman, J. E. (2023) Perceptions of pharmacists on the quality of automated blood pressure devices: a national survey. Journal of Human Hypertension, 37(3), pp. 235-240. (doi: 10.1038/s41371-022-00670-4) (PMID:35314763)
Chen, J. Y., Chew, K. S., Mary, S. , Boder, P., Bagordo, D., Rossi, G. P., Touyz, R. M. , Delles, C. and Rossitto, G. (2023) Skin-specific mechanisms of body fluid regulation in hypertension. Clinical Science, 137(3), pp. 239-250. (doi: 10.1042/CS20220609) (PMID:36648486)
de Beer, D., Mels, C. M. C., Schutte, A. E., Delles, C. , Mary, S. , Mullen, W. , Mischak, H. and Kruger, R. (2023) A urinary peptidomics approach for early stages of cardiovascular disease risk: the African-PREDICT study. Hypertension Research, 46(2), pp. 485-494. (doi: 10.1038/s41440-022-01097-7) (PMID:36396816)
Lim, M. W.S., Setjiadi, D., Dobbin, S. J.H., Lang, N. N. , Delles, C. and Connelly, P. J. (2023) Nailfold video-capillaroscopy in the study of cardiovascular disease: a systematic review. Blood Pressure Monitoring, 28(1), pp. 24-32. (doi: 10.1097/MBP.0000000000000624) (PMID:36281701) (PMCID:PMC9815820)
Rushworth, L. K. et al. (2023) Phase II proof of concept study of atorvastatin in castration resistant prostate cancer. BJU International, 131(2), pp. 236-243. (doi: 10.1111/bju.15851) (PMID:35844167) (PMCID:PMC10087532)
Sharman, J. E. et al. (2023) The urgency to regulate validation of automated blood pressure measuring devices: a policy statement and call to action from the world hypertension league. Journal of Human Hypertension, 37(2), pp. 155-159. (doi: 10.1038/s41371-022-00747-0) (PMID:36476777) (PMCID:PMC9957720)
Sattar, N. , Deanfield, J. and Delles, C. (2023) Impact of intentional weight loss in cardiometabolic disease: what we know about timing of benefits on differing outcomes? Cardiovascular Research, (doi: 10.1093/cvr/cvac186) (PMID:36683167) (Early Online Publication)
Sykes, R. et al. (2023) Adjudicated myocarditis and multisystem illness trajectory in healthcare workers post-COVID-19. Open Heart, 10(1), e002192. (doi: 10.1136/openhrt-2022-002192) (PMID:36822817) (PMCID:PMC9950584)
Kulkarni, S., Glover, M., Kapil, V., Abrams, S. M. L., Partridge, S., McCormack, T., Sever, P., Delles, C. and Wilkinson, I. B. (2023) Management of hypertensive crisis: British and Irish Hypertension Society position document. Journal of Human Hypertension, (doi: 10.1038/s41371-022-00776-9) (PMID:36418425) (Early Online Publication)
2022
Murray, E. C. , Delles, C. , Orzechowski, P., Renc, P., Sitek, A., Wagenaar, J. and Guzik, T. J. (2022) Vascular phenotypes in early hypertension. Journal of Human Hypertension, (doi: 10.1038/s41371-022-00794-7) (Early Online Publication)
Rossitto, G. and Delles, C. (2022) Mechanisms of sodium-mediated injury in cardiovascular disease: old play, new scripts. FEBS Journal, 289(23), pp. 7260-7273. (doi: 10.1111/febs.16155) (PMID:34355504)
Mary, S. , Boder, P., Padmanabhan, S. , McBride, M. W. , Graham, D. , Delles, C. and Dominiczak, A. F. (2022) The role of uromodulin in salt-sensitive hypertension. Hypertension, 79, pp. 2419-2429. (doi: 10.1161/HYPERTENSIONAHA.122.19888) (PMID:36378920) (PMCID:PMC9553220)
Lip, S. , McCallum, L., Delles, C. , McClure, J. D. , Guzik, T., Berry, C. , Touyz, R. and Padmanabhan, S. (2022) Rationale and design for the LOnger-term effects of SARS-CoV-2 INfection on blood Vessels And blood pRessure (LOCHINVAR). Open Heart, 9(1), e002057. (doi: 10.1136/openhrt-2022-002057) (PMID:35750422) (PMCID:PMC9234432)
Connelly, P. J. , Currie, G. and Delles, C. (2022) Sex differences in the prevalence, outcomes and management of hypertension. Current Hypertension Reports, 24(6), pp. 185-192. (doi: 10.1007/s11906-022-01183-8) (PMID:35254589) (PMCID:PMC9239955)
Craig, A., Delles, C. and Murray, E. C. (2022) A review of vascular traits and assessment techniques, and their heritability. Artery Research, 28(2), pp. 61-78. (doi: 10.1007/s44200-022-00016-y)
Lucas-Herald, A. K. and Delles, C. (2022) Carotid intima-media thickness is associated with obesity and hypertension in young people. Hypertension, 79(6), pp. 1177-1179. (doi: 10.1161/hypertensionaha.122.19163) (PMID:35544586)
Rastogi, T. et al. (2022) Comparing and contrasting risk factors for heart failure in patients with and without history of myocardial infarction: data from HOMAGE and the UK Biobank. European Journal of Heart Failure, 24(6), pp. 976-984. (doi: 10.1002/ejhf.2495) (PMID:35365899) (PMCID:PMC9542039)
Wang, Y. et al. (2022) Associations of long-term visit-to-visit blood pressure variability with subclinical kidney damage and albuminuria in adulthood: a 30-year prospective cohort study. Hypertension, 79(6), pp. 1247-1256. (doi: 10.1161/HYPERTENSIONAHA.121.18658) (PMID:35360932) (PMCID:PMC9093226)
Lucas-Herald, A. K. et al. (2022) Vascular dysfunction and increased cardiovascular risk in hypospadias. European Heart Journal, 43(19), pp. 1832-1845. (doi: 10.1093/eurheartj/ehac112) (PMID:35567552) (PMCID:PMC9113289)
Rossitto, G. and Delles, C. (2022) Does excess tissue sodium storage regulate blood pressure? Current Hypertension Reports, 24(5), pp. 115-122. (doi: 10.1007/s11906-022-01180-x) (PMID:35192140) (PMCID:PMC9142429)
Maurovich-Horvat, P. et al. (2022) CT or invasive coronary angiography in stable chest pain. New England Journal of Medicine, 386(17), pp. 1591-1602. (doi: 10.1056/NEJMoa2200963) (PMID:35240010)
Toloza, F. J. K. et al. (2022) Association between maternal thyroid function and risk of gestational hypertension and pre-eclampsia: a systematic review and individual-participant data meta-analysis. Lancet Diabetes and Endocrinology, 10(4), pp. 243-252. (doi: 10.1016/S2213-8587(22)00007-9) (PMID:35255260)
Connelly, P. J. , Casey, H., Montezano, A. C., Touyz, R. M. and Delles, C. (2022) Sex steroids receptors, hypertension and vascular ageing. Journal of Human Hypertension, 36(2), pp. 120-125. (doi: 10.1038/s41371-021-00576-7) (PMID:34230581) (PMCID:PMC8850193)
Mujaj, B. et al. (2022) Aspirin use is associated with increased risk for incident heart failure: a patient-level pooled analysis. ESC Heart Failure, 9(1), pp. 685-694. (doi: 10.1002/ehf2.13688) (PMID:34808706) (PMCID:PMC8787993)
Delles, C. (2022) Maternally inherited essential hypertension: adding further complexity to an already complex condition. American Journal of Hypertension, 35(1), pp. 16-18. (doi: 10.1093/ajh/hpab133) (PMID:34427578) (PMCID:PMC8730502)
Delles, C. and Rossitto, G. (2022) Of snails, earthworms, and men: insights into strategies to preserve water. Function, 3(1), zqab071. (doi: 10.1093/function/zqab071) (PMID:35330922) (PMCID:PMC8788808)
2021
Connelly, P. J. and Delles, C. (2021) Cardiovascular disease in transgender people: recent research and emerging evidence. Cardiovascular Research, 117(14), e174-e176. (doi: 10.1093/cvr/cvab288) (PMID:34568899) (PMCID:PMC8683701)
Mary, S. , Boder, P., Rossitto, G., Graham, L., Scott, K. , Flynn, A., Kipgen, D., Graham, D. and Delles, C. (2021) Salt loading decreases urinary excretion and increases intracellular accumulation of uromodulin in stroke-prone spontaneously hypertensive rats. Clinical Science, 135(24), pp. 2749-2761. (doi: 10.1042/CS20211017) (PMID:34870708) (PMCID:PMC8689196)
van Vliet, N. A. et al. (2021) Higher thyrotropin leads to unfavorable lipid profile and somewhat higher cardiovascular disease risk: evidence from multi-cohort Mendelian randomization and metabolomic profiling. BMC Medicine, 19, 266. (doi: 10.1186/s12916-021-02130-1) (PMID:34727949) (PMCID:PMC8565073)
He, T. et al. (2021) Urinary peptides in heart failure: a link to molecular pathophysiology. European Journal of Heart Failure, 23(11), pp. 1875-1887. (doi: 10.1002/ejhf.2195) (PMID:33881206)
Raafs, A. et al. (2021) Identification of sex‐specific biomarkers predicting new‐onset heart failure. ESC Heart Failure, 8(5), pp. 3512-3520. (doi: 10.1002/ehf2.13476) (PMID:34156155) (PMCID:PMC8497379)
Touyz, R. M. et al. (2021) Cardiovascular and renal risk factors and complications associated with COVID-19. CJC Open, 3(10), pp. 1257-1272. (doi: 10.1016/j.cjco.2021.05.020) (PMID:34151246) (PMCID:PMC8205551)
Docherty, N. G., Delles, C. , D’Haese, P., Layton, A. T., Martínez-Salgado, C., Vervaet, B. A. and López-Hernández, F. J. (2021) Haemodynamic frailty – A risk factor for acute kidney injury in the elderly. Ageing Research Reviews, 70, 101408. (doi: 10.1016/j.arr.2021.101408) (PMID:34271185)
Boder, P., Mary, S. , Mark, P. B. , Leiper, J. , Dominiczak, A. F. , Padmanabhan, S. , Rampold, L. and Delles, C. (2021) Mechanistic interactions of uromodulin with the thick ascending limb: perspectives in physiology and hypertension. Journal of Hypertension, 39(8), pp. 1490-1504. (doi: 10.1097/HJH.0000000000002861) (PMID:34187999) (PMCID:PMC7611110)
Mary, S. , Small, H., Herse, F., Carrick, E., Flynn, A., Mullen, W. , Dechend, R. and Delles, C. (2021) Pre-existing hypertension and pregnancy induced hypertension reveal molecular differences in placental proteome in rodents. Physiological Genomics, 53(6), pp. 259-268. (doi: 10.1152/physiolgenomics.00160.2020) (PMID:33969702)
Murray, E. , Rossitto, G. and Delles, C. (2021) Haemodynamic assessment in hypertension: the soloists and the orchestra. Journal of Hypertension, 39(6), pp. 1109-1111. (doi: 10.1097/HJH.0000000000002796) (PMID:33967215)
Rossitto, G. et al. (2021) High sodium intake, glomerular hyperfiltration and protein catabolism in patients with essential hypertension. Cardiovascular Research, 117(5), pp. 1372-1381. (doi: 10.1093/cvr/cvaa205) (PMID:33053160) (PMCID:PMC8064429)
Connelly, P. J. , Azizi, Z., Alipour, P., Delles, C. , Pilote, L. and Raparelli, V. (2021) The importance of gender to understand sex differences in cardiovascular disease. Canadian Journal of Cardiology, 37(5), pp. 699-710. (doi: 10.1016/j.cjca.2021.02.005) (PMID:33592281)
Scott, K. , Morgan, H. L., Delles, C. , Fisher, S., Graham, D. and McBride, M. W. (2021) Distinct uterine artery gene expression profiles during early gestation in the stroke-prone spontaneously hypertensive rat. Physiological Genomics, 53(4), pp. 160-171. (doi: 10.1152/physiolgenomics.00159.2020) (PMID:33719581)
Vlahou, A. et al. (2021) Data sharing under the General Data Protection Regulation: time to harmonize law and research ethics? Hypertension, 77(4), pp. 1029-1035. (doi: 10.1161/HYPERTENSIONAHA.120.16340) (PMID:33583200) (PMCID:PMC7968961)
Crouch, S. H., Botha-Le Roux, S., Delles, C. , Graham, L. A. and Schutte, A. E. (2021) Inflammation and salt in young adults: the African-PREDICT study. European Journal of Nutrition, 60(2), pp. 873-882. (doi: 10.1007/s00394-020-02292-3) (PMID:32494865) (PMCID:PMC7900065)
Neves, K. B. , Morris, H., Alves-Lopes, R., Muir, K. W. , Moreton, F., Delles, C. , Montezano, A. C. and Touyz, R. M. (2021) Peripheral arteriopathy caused by Notch3 gain-of-function mutation involves ER and oxidative stress and blunting of NO∕sGC∕cGMP pathway. Clinical Science, 135(6), pp. 753-773. (doi: 10.1042/CS20201412) (PMID:33681964)
Connelly, P. J. , Clark, A., Touyz, R. M. and Delles, C. (2021) Transgender adults, gender-affirming hormone therapy and blood pressure: a systematic review. Journal of Hypertension, 39(2), pp. 223-230. (doi: 10.1097/HJH.0000000000002632) (PMID:32809982) (PMCID:PMC7810409)
Moreton, F. C., Cullen, B. , Dickie, D. A. , Lopez Gonzalez, R., Santosh, C., Delles, C. and Muir, K. W. (2021) Brain imaging factors associated with progression of subcortical hyperintensities in CADASIL over two year follow up. European Journal of Neurology, 28(1), pp. 220-228. (doi: 10.1111/ene.14534) (PMID:32931073)
Small, H. Y. and Delles, C. (2021) Letter to the Editor regarding Cunningham et al. 2020. Hypertension in Pregnancy, 40(2), p. 133. (doi: 10.1080/10641955.2021.1899201) (PMID:33834935)
2020
Rossitto, G. et al. (2020) Reduced lymphatic reserve in heart failure with preserved ejection fraction. Journal of the American College of Cardiology, 76(24), pp. 2817-2829. (doi: 10.1016/j.jacc.2020.10.022) (PMID:33303070) (PMCID:PMC7724570)
Mangion, K. et al. (2020) The Chief Scientist Office cardiovascular and pulmonary imaging in SARS Coronavirus disease-19 (CISCO-19) study. Cardiovascular Research, 116(14), pp. 2185-2196. (doi: 10.1093/cvr/cvaa209) (PMID:32702087) (PMCID:PMC7454350)
Rossitto, G. et al. (2020) Tissue sodium excess is not hypertonic and reflects extracellular volume expansion. Nature Communications, 11, 4222. (doi: 10.1038/s41467-020-17820-2) (PMID:32839436) (PMCID:PMC7445299)
Campbell, R. T. et al. (2020) The novel urinary proteomic classifier HF1 has similar diagnostic and prognostic utility to BNP in heart failure. ESC Heart Failure, 7(4), pp. 1595-1604. (doi: 10.1002/ehf2.12708) (PMID:32383555) (PMCID:PMC7373887)
Connelly, P. J. , Jandeleit-Dahm, K. A.M. and Delles, C. (2020) Sex and gender aspects in vascular pathophysiology. Clinical Science, 134(16), pp. 2203-2207. (doi: 10.1042/CS20200876) (PMID:32844996)
Demin, A., Løge, B., Zhiteneva, O., Nishida, C., Whiting, S., Rippin, H., Delles, C. , Karymbaeva, S., Wickramasinghe, K. and Breda, J. (2020) Trans fatty acid elimination policy in member states of the Eurasian Economic Union: implementation challenges and capacity for enforcement. Journal of Clinical Hypertension, 22(8), pp. 1328-1337. (doi: 10.1111/jch.13945) (PMID:32677762)
Dobbie, L. J., Mackin, S. T., Hogarth, K., Lonergan, F., Kannenkeril, D., Brooksbank, K. and Delles, C. (2020) Validation of semi-automated flow mediated dilation measurement in healthy volunteers. Blood Pressure Monitoring, 25(4), pp. 216-223. (doi: 10.1097/MBP.0000000000000448) (PMID:32304385) (PMCID:PMC7331823)
Tarar, O. M., Ahmed, K. M., Nishtar, N. A., Achakzai, A. B. K., Gulzar, Y., Delles, C. and Al-Jawaldeh, A. (2020) Understanding the complexities of prevalence of trans fat and its control in food supply in Pakistan. Journal of Clinical Hypertension, 22(8), pp. 1338-1346. (doi: 10.1111/jch.13943) (PMID:32687252)
Currie, G. , Mary, S. and Delles, C. (2020) Is there a role for proteomics in diabetic renal disease? NDT Plus, 35(7), pp. 1133-1135. (doi: 10.1093/ndt/gfz017) (PMID:32777079) (PMCID:PMC7417003)
Derakhshan, A. et al. (2020) Association of maternal thyroid function with birth weight: a systematic review and individual-participant data meta-analysis. Lancet Diabetes and Endocrinology, 8(6), pp. 501-510. (doi: 10.1016/S2213-8587(20)30061-9) (PMID:32445737)
Picone, D. S. et al. (2020) Nonvalidated home blood pressure devices dominate the online marketplace in Australia: major implications for cardiovascular risk management. Hypertension, 75(6), pp. 1593-1599. (doi: 10.1161/hypertensionaha.120.14719) (PMID:32275193)
Delles, C. and Olfert, M. (2020) Electronic cigarettes: how bad are they for your health? Cardiovascular Research, 116(6), e64-e66. (doi: 10.1093/cvr/cvaa041) (PMID:32157289)
Delles, C. , Li, H. and Touyz, R. M. (2020) ACE2 the Janus-faced protein – from cardiovascular protection to severe acute respiratory syndrome-coronavirus and COVID-19. Clinical Science, 134(7), pp. 747-750. (doi: 10.1042/CS20200363)
Tofte, N. et al. (2020) Early detection of diabetic kidney disease by urinary proteomics and subsequent intervention with spironolactone to delay progression (PRIORITY): a prospective observational study and embedded randomised placebo-controlled trial. Lancet Diabetes and Endocrinology, 8(4), pp. 301-312. (doi: 10.1016/S2213-8587(20)30026-7) (PMID:32135136)
Crouch, S. H., Botha-Le Roux, S., Delles, C. , Graham, L. A. and Schutte, A. E. (2020) Distinct inflammatory mediator patterns in young black and white adults: The African-PREDICT study. Cytokine, 126, 154894. (doi: 10.1016/j.cyto.2019.154894)
Schlosser, K., Kaur, A., Dayan, N., Stewart, D. J., Pilote, L. and Delles, C. (2020) Circulating miR-206 and Wnt-signaling are associated with cardiovascular complications and a history of preeclampsia in women. Clinical Science, 134(2), pp. 87-101. (doi: 10.1042/CS20190920) (PMID:31899480)
Mary, S. , Currie, G. , Schutte, A. E. and Delles, C. (2020) Cardiovascular proteomics. In: Faintuch, J. and Faintuch, S. (eds.) Precision Medicine for Investigators, Practitioners and Providers. Academic Press: London ; San Diego, CA, pp. 263-270. ISBN 9780128191781 (doi: 10.1016/b978-0-12-819178-1.00025-3)
2019
Neves, K. B. et al. (2019) ER stress and Rho kinase activation underlie the vasculopathy of CADASIL. JCI Insight, 4(23), e131344. (doi: 10.1172/jci.insight.131344) (PMID:31647781) (PMCID:PMC6962020)
Cameron, A. C. et al. (2019) Progressive hypertension and severe left ventricular outflow tract obstruction. Hypertension, 74(6), pp. 1216-1225. (doi: 10.1161/hypertensionaha.119.13343) (PMID:31587571)
Connelly, P. J. , Freel, E. M., Perry, C., Ewan, J., Touyz, R. M. , Currie, G. and Delles, C. (2019) Gender-affirming hormone therapy, vascular health and cardiovascular disease in transgender adults. Hypertension, 74(6), pp. 1266-1274. (doi: 10.1161/HYPERTENSIONAHA.119.13080) (PMID:31656099) (PMCID:PMC6887638)
Iliodromiti, S., Sattar, N. , Delles, C. , Nelson, S. M. , Gill, J. M.R. and Lumsden, M. (2019) Menopausal hot flashing and endothelial function in two vascular beds: findings from a cross-sectional study of postmenopausal women. Menopause, 26(9), pp. 1002-1009. (doi: 10.1097/GME.0000000000001386) (PMID:31453962)
Korevaar, T. I. M. et al. (2019) Association of thyroid function test abnormalities and thyroid autoimmunity with preterm birth: a systematic review and meta-analysis. JAMA: Journal of the American Medical Association, 322(7), pp. 632-641. (doi: 10.1001/jama.2019.10931) (PMID:31429897) (PMCID:PMC6704759)
Welsh, C. et al. (2019) Urinary sodium excretion, blood pressure and risk of future cardiovascular disease and mortality in subjects without prior cardiovascular disease. Hypertension, 73, pp. 1202-1209. (doi: 10.1161/HYPERTENSIONAHA.119.12726) (PMID:31067194)
Schanstra, J. P. et al. (2019) Systems biology identifies cytosolic PLA2 as a target in vascular calcification treatment. JCI Insight, 4(10), e125638. (doi: 10.1172/jci.insight.125638)
Small, H. Y., McNeilly, S., Mary, S. , Sheikh, A. M. and Delles, C. (2019) Resistin mediates sex-dependent effects of perivascular adipose tissue on vascular function in the SHRSP. Scientific Reports, 9, 6897. (doi: 10.1038/s41598-019-43326-z) (PMID:31053755) (PMCID:PMC6499830)
Currie, G. and Delles, C. (2019) Vascular biomedicine in an era of chronic disease and multimorbidity. Clinical Science, 133(9), pp. 1137-1143. (doi: 10.1042/CS20180764) (PMID:31088896) (PMCID:PMC6522703)
Ferreira, J. P. et al. (2019) Proteomic bioprofiles and mechanistic pathways of progression to heart failure: the HOMAGE study. Circulation, 12(5), e005897. (doi: 10.1161/CIRCHEARTFAILURE.118.005897) (PMID:31104495)
Lucas-Herald, A. K. , Zürbig, P., Mason, A., Kinning, E., Brown, C. E., Mansoorian, B., Mullen, W. , Ahmed, S. F. and Delles, C. (2019) Proteomic evidence of biological aging in a child with a compound heterozygous ZMPSTE24 mutation. Proteomics Clinical Applications, 13(2), 1800135. (doi: 10.1002/prca.201800135) (PMID:30548811) (PMCID:PMC6492098)
Kerr, D. M.I., Brooksbank, K. J.M., Taylor, R. G., Pinel, K., Rios, F. J. , Touyz, R. M. and Delles, C. (2019) Acute effects of electronic and tobacco cigarettes on vascular and respiratory function in healthy volunteers: a cross-over study. Journal of Hypertension, 37(1), pp. 154-166. (doi: 10.1097/HJH.0000000000001890) (PMID:30063637)
Touyz, R. M. and Delles, C. (Eds.) (2019) Textbook of Vascular Medicine. Springer: Cham. ISBN 9783030164805
Ravassa, S., Delles, C. , Currie, G. and Díez, J. (2019) Biomarkers of cardiovascular disease. In: Touyz, R. M. and Delles, C. (eds.) Textbook of Vascular Medicine. Springer: Cham, pp. 319-330. ISBN 9783030164805 (doi: 10.1007/978-3-030-16481-2_30)
Small, H. Y., Currie, G. and Delles, C. (2019) Endothelial dysfunction. In: Touyz, R. M. and Delles, C. (eds.) Textbook of Vascular Medicine. Springer: Cham, pp. 183-192. ISBN 9783030164805 (doi: 10.1007/978-3-030-16481-2_17)
2018
Rossitto, G., Touyz, R. M. , Petrie, M. C. and Delles, C. (2018) Much Ado about N...atrium: modelling tissuesodium as a highly sensitive marker of subclinicaland localized oedema. Clinical Science, 132(24), pp. 2609-2613. (doi: 10.1042/CS20180575) (PMID:30545897) (PMCID:PMC6365627)
Sliz, E. et al. (2018) Metabolomic consequences of genetic inhibition of PCSK9 compared with statin treatment. Circulation, 138(22), pp. 2499-2512. (doi: 10.1161/CIRCULATIONAHA.118.034942) (PMID:30524137)
Dayan, N., Schlosser, K., Stewart, D. J., Delles, C. , Kaur, A. and Pilote, L. (2018) Circulating microRNAs implicate multiple atherogenic abnormalities in the long-term cardiovascular sequelae of preeclampsia. American Journal of Hypertension, 31(10), pp. 1093-1097. (doi: 10.1093/ajh/hpy069) (PMID:29800045) (PMCID:PMC6132124)
Tofte, N. et al. (2018) Characteristics of high- and low-risk individuals in the PRIORITY study: urinary proteomics and mineralocorticoid receptor antagonism for prevention of diabetic nephropathy in Type 2 diabetes. Diabetic Medicine, 35(10), pp. 1375-1382. (doi: 10.1111/dme.13669) (PMID:29781558)
Ravassa, S. et al. (2018) Biomarker-based phenotyping of myocardial fibrosis identifies patients with heart failure with preserved ejection fraction resistant to the beneficial effects of spironolactone: results from the Aldo-DHF trial. European Journal of Heart Failure, 20(9), pp. 1290-1299. (doi: 10.1002/ejhf.1194) (PMID:29709099)
Gillis, K. , Stevens, K. K., Bell, E., Patel, R. K., Jardine, A. G. , Morris, S. T.W., Schneider, M. P., Delles, C. and Mark, P. B. (2018) Ascorbic acid lowers central blood pressure and asymmetric dimethylarginine in chronic kidney disease. Clinical Kidney Journal, 11(4), pp. 532-539. (doi: 10.1093/ckj/sfx158) (PMID:30094018) (PMCID:PMC6070083)
Moreton, F. C., Cullen, B. , Delles, C. , Santosh, C., Lopez Gonzalez, R., Dani, K. and Muir, K. W. (2018) Vasoreactivity in CADASIL: comparison to structural MRI and neuropsychology. Journal of Cerebral Blood Flow and Metabolism, 38(6), pp. 1085-1095. (doi: 10.1177/0271678X17710375) (PMID:28537106)
Lygirou, V., Latosinska, A., Makridakis, M., Mullen, W. , Delles, C. , Schanstra, J. P., Zoidakis, J., Pieske, B., Mischak, H. and Vlahou, A. (2018) Plasma proteomic analysis reveals altered protein abundances in cardiovascular disease. Journal of Translational Medicine, 16(1), 104. (doi: 10.1186/s12967-018-1476-9) (PMID:29665821) (PMCID:PMC5905170)
Currie, G. E. et al. (2018) Urinary proteomics for prediction of mortality in patients with type 2 diabetes and microalbuminuria. Cardiovascular Diabetology, 17, 50. (doi: 10.1186/s12933-018-0697-9) (PMID:29625564) (PMCID:PMC5889591)
Delles, C. and Currie, G. (2018) Sex differences in hypertension and other cardiovascular diseases. Journal of Hypertension, 36(4), pp. 768-770. (doi: 10.1097/HJH.0000000000001655) (PMID:29489615) (PMCID:PMCID: PMC5856361)
Delles, C. et al. (2018) Nuclear magnetic resonance-based metabolomics identifies phenylalanine as a novel predictor of incident heart failure hospitalisation: results from PROSPER and FINRISK 1997. European Journal of Heart Failure, 20, pp. 663-673. (doi: 10.1002/ejhf.1076) (PMID:29226610) (PMCID:PMC5947152)
Feng, Y.-M. et al. (2018) Glomerular function in relation to circulating adhesion molecules and inflammation markers in a general population. Nephrology Dialysis Transplantation, 33(3), pp. 426-435. (doi: 10.1093/ndt/gfx256) (PMID:28992257)
Currie, G. and Delles, C. (2018) Blood pressure targets in the elderly. Journal of Hypertension, 36(2), pp. 234-236. (doi: 10.1097/HJH.0000000000001576)
Delles, C. , Carrick, E., Graham, D. and Nicklin, S. A. (2018) Utilising proteomics to understand and define hypertension: where are we and where do we go? Expert Review of Proteomics, 15(7), pp. 581-592. (doi: 10.1080/14789450.2018.1493927) (PMID:29999442) (PMCID:PMC6092739)
2017
Krochmal, M. et al. (2017) Urinary peptidomics analysis reveals proteases involved in diabetic nephropathy. Scientific Reports, 7, 15160. (doi: 10.1038/s41598-017-15359-9) (PMID:29123184) (PMCID:PMC5680307)
Pontillo, C. et al. (2017) Prediction of chronic kidney disease stage 3 by CKD273, a urinary proteomic biomarker. Kidney International Reports, 2(6), pp. 1066-1075. (doi: 10.1016/j.ekir.2017.06.004) (PMID:29130072) (PMCID:PMC5669285)
Schmieder, R. E. et al. (2017) The effect of sacubitril/valsartan compared to olmesartan on cardiovascular remodelling in subjects with essential hypertension: the results of a randomized, double-blind, active-controlled study. European Heart Journal, 38(44), pp. 3308-3317. (doi: 10.1093/eurheartj/ehx525) (PMID:29029087)
Kohli-Lynch, C.N. , Boyd, K. , Briggs, A. and Delles, C. (2017) A Framework for the Cost-Effectiveness Analysis of Novel Biomarker Testing in Cardiovascular Disease. ISPOR 20th Annual European Congress, Glasgow, UK, 4-8 Nov 2017. A404-A405. (doi: 10.1016/j.jval.2017.08.040)
Stevens, K., Denby, L., Patel, R. K., Mark, P. B. , Kettlewell, S., Smith, G. L. , Clancy, M. J., Delles, C. and Jardine, A. G. (2017) Deleterious effects of phosphate on vascular and endothelial function via disruption to the nitric oxide pathway. Nephrology Dialysis Transplantation, 32(10), pp. 1617-1627. (doi: 10.1093/ndt/gfw252) (PMID:27448672) (PMCID:PMC5837731)
Krochmal, M. et al. (2017) Identification of novel molecular signatures of IgA nephropathy through an integrative -omics analysis. Scientific Reports, 7, 9091. (doi: 10.1038/s41598-017-09393-w) (PMID:28831120) (PMCID:PMC5567309)
Currie, G. and Delles, C. (2017) Healthy vascular ageing. Hypertension, 70(2), pp. 229-231. (doi: 10.1161/HYPERTENSIONAHA.117.09122) (PMID:28559393)
Gajjala, P. R. et al. (2017) Proteomic-biostatistic integrated approach for finding the underlying molecular determinants of hypertension in human plasma. Hypertension, 70, pp. 412-419. (doi: 10.1161/HYPERTENSIONAHA.116.08906) (PMID:28652472)
Small, H. Y., Cornelius, D. C., Guzik, T. J. and Delles, C. (2017) Natural killer cells in placentation and cancer: Implications for hypertension during pregnancy. Placenta, 56, pp. 59-64. (doi: 10.1016/j.placenta.2017.03.003) (PMID:28318556)
Zhang, Z.‐Y. et al. (2017) Novel urinary peptidomic classifier predicts incident heart failure. Journal of the American Heart Association, 6(8), e005432. (doi: 10.1161/JAHA.116.005432) (PMID:28784649) (PMCID:PMC5586413)
Knez, J. et al. (2017) Peripheral blood mitochondrial DNA content in relation to circulating metabolites and inflammatory markers: a population study. PLoS ONE, 12(7), e0181036. (doi: 10.1371/journal.pone.0181036) (PMID:28704533) (PMCID:PMC5509283)
Neisius, U., Olson, E., Rossi, S. H., Ibrahim, H. A., Currie, G. , Dominiczak, A. and Delles, C. (2017) Evaluation of the systemic micro- and macrovasculature in stable angina: a case-control study. PLoS ONE, 12(5), e0178412. (doi: 10.1371/journal.pone.0178412) (PMID:28542516) (PMCID:PMC5444845)
Jacobs, L. et al. (2017) Risk for incident heart failure: a subject-level meta-analysis from the Heart “OMics” in AGEing (HOMAGE) study. Journal of the American Heart Association, 6(5), e005231. (doi: 10.1161/JAHA.116.005231) (PMID:28465299)
Mary, S. , Small, H. Y., Siwy, J., Mullen, W. , Giri, A. and Delles, C. (2017) Polymerization-incompetent uromodulin in the pregnant stroke-prone spontaneously hypertensive rat. Hypertension, 69(5), pp. 910-918. (doi: 10.1161/HYPERTENSIONAHA.116.08826) (PMID:28348009) (PMCID:PMC5389592)
Dominiczak, A. , Delles, C. and Padmanabhan, S. (2017) Genomics and precision medicine for clinicians and scientists in hypertension. Hypertension, 69(4), e10-e13. (doi: 10.1161/HYPERTENSIONAHA.116.08252) (PMID:28193712)
Htun, N. M. et al. (2017) Prediction of acute coronary syndromes by urinary proteome analysis. PLoS ONE, 12(3), e0172036.. (doi: 10.1371/journal.pone.0172036) (PMID:28273075) (PMCID:PMC5342174)
Carty, D. M., Doogan, F., Welsh, P. , Dominiczak, A. F. and Delles, C. (2017) Thyroid stimulating hormone (TSH) ≥2.5mU/l in early pregnancy: prevalence and subsequent outcomes. European Journal of Obstetrics and Gynecology and Reproductive Biology, 210, pp. 366-369. (doi: 10.1016/j.ejogrb.2017.01.048) (PMID:28153744)
Currie, G. and Delles, C. (2017) The future of "omics" in hypertension. Canadian Journal of Cardiology, 33(5), pp. 601-610. (doi: 10.1016/j.cjca.2016.11.023) (PMID:28161100) (PMCID:5417769)
Small, H. Y., Akehurst, C., Sharafetdinova, L., McBride, M. W. , McClure, J. D. , Robinson, S. W., Carty, D. M., Freeman, D. J. and Delles, C. (2017) HLA gene expression is altered in whole blood and placenta from women who later developed preeclampsia. Physiological Genomics, 49(3), pp. 193-200. (doi: 10.1152/physiolgenomics.00106.2016) (PMID:28130428) (PMCID:PMC5374453)
Delles, C. and Husi, H. (2017) Systems biology approach in hypertension research. In: Touyz, R. M. and Schriffin, E. L. (eds.) Hypertension: Methods and Protocols. Series: Methods in molecular biology, 1527. Springer: New York, pp. 69-79. ISBN 9781493966233 (doi: 10.1007/978-1-4939-6625-7_6)
Delles, C. and Vanholder, R. (2017) Chronic kidney disease. Clinical Science, 131(3), pp. 225-226. (doi: 10.1042/CS20160624) (PMID:28057893)
2016
Ferreira, J. P. et al. (2016) Renal function estimation and Cockroft–Gault formulas for predicting cardiovascular mortality in population-based, cardiovascular risk, heart failure and post-myocardial infarction cohorts: the Heart ‘OMics’ in AGEing (HOMAGE) and the high-risk myocardial infarction database initiatives. BMC Medicine, 14, 181. (doi: 10.1186/s12916-016-0731-2) (PMID:27829460) (PMCID:PMC5103492)
Rutherford, C. et al. (2016) Phosphorylation of Janus kinase 1 (JAK1) by AMP-activated protein kinase (AMPK) links energy sensing to anti-inflammatory signaling. Science Signaling, 9(453), ra109. (doi: 10.1126/scisignal.aaf8566) (PMID:27919027)
Currie, G. and Delles, C. (2016) Urinary proteomics for diagnosis and monitoring of diabetic nephropathy. Current Diabetes Reports, 16(11), 104. (doi: 10.1007/s11892-016-0798-3) (PMID:27658932)
Small, H. Y., Nosalski, R., Morgan, H., Beattie, E., Guzik, T., Graham, D. and Delles, C. (2016) The role of tumor necrosis factor-α and natural killer cells in uterine artery function and pregnancy outcome in the stroke prone spontaneously hypertensive rat. Hypertension, 68(5), pp. 1298-1307. (doi: 10.1161/HYPERTENSIONAHA.116.07933) (PMID:27733586) (PMCID:PMC5058643)
Currie, G. , Matt, P. and Delles, C. (2016) Clinical cardiovascular proteomics. In: Agnetti, G., Lindsey, M. L. and Foster, D. B. (eds.) Manual of Cardiovascular Proteomics. Springer, pp. 389-414. ISBN 9783319318264 (doi: 10.1007/978-3-319-31828-8_17)
Currie, G. et al. (2016) Effect of mineralocorticoid receptor antagonists on proteinuria and progression of chronic kidney disease: a systematic review and meta-analysis. BMC Nephrology, 17, 127. (doi: 10.1186/s12882-016-0337-0) (PMID:27609359) (PMCID:PMC5015203)
Mordi, I., Mordi, N., Delles, C. and Tzemos, N. (2016) Endothelial dysfunction in human essential hypertension. Journal of Hypertension, 34(8), pp. 1464-1472. (doi: 10.1097/hjh.0000000000000965) (PMID:27203578)
Currie, G. and Delles, C. (2016) Use of biomarkers in the evaluation and treatment of hypertensive patients. Current Hypertension Reports, 18(7), 54. (doi: 10.1007/s11906-016-0661-6) (PMID:27221728)
Wan Sulaiman, W.N., Caslake, M.J., Delles, C. , Karlsson, H., Mulder, M.T., Graham, D. and Freeman, D.J. (2016) Does high-density lipoprotein protect vascular function in healthy pregnancy? Clinical Science, 130(7), pp. 491-497. (doi: 10.1042/cs20150475) (PMID:26888561)
Eisele, N. et al. (2016) Placental expression of the angiogenic placental growth factor is stimulated by both aldosterone and simulated starvation. Placenta, 40, pp. 18-24. (doi: 10.1016/j.placenta.2016.02.004) (PMID:27016778)
Neisius, U. et al. (2016) Urine proteomics in the diagnosis of stable angina. BMC Cardiovascular Disorders, 16, 70. (doi: 10.1186/s12872-016-0246-y) (PMID:27095611) (PMCID:PMC483761)
Mullan, A., Delles, C. , Ferrell, W., Mullen, W. , Edwards, C. A. , McColl, J. H. , Roberts, S. A. and Lean, M. (2016) Effects of a beverage rich in (poly)phenols on established and novel risk markers for vascular disease in medically uncomplicated overweight or obese subjects: A four week randomized trial. Atherosclerosis, 246, pp. 169-176. (doi: 10.1016/j.atherosclerosis.2016.01.004) (PMID:26797134)
Currie, G. , Delles, C. , Touyz, R. M. , Staessen, J. A., Dominiczak, A. F. , Jennings, G. L. R. and Wang, J.-G. (2016) A woman with treatment-resistant hypertension. Hypertension, 67(2), pp. 243-250. (doi: 10.1161/HYPERTENSIONAHA.115.06756) (PMID:26711735)
Small, H. Y., Currie, G. E. and Delles, C. (2016) Prostasin, proteases, and preeclampsia. Journal of Hypertension, 34(2), pp. 193-195. (doi: 10.1097/hjh.0000000000000828) (PMID:26682786)
Small, H. Y., Morgan, H., Beattie, E., Griffin, S., Indahl, M., Delles, C. and Graham, D. (2016) Abnormal uterine artery remodelling in the stroke prone spontaneously hypertensive rat. Placenta, 37, pp. 34-44. (doi: 10.1016/j.placenta.2015.10.022) (PMID:26612342) (PMCID:PMC4721537)
Gillis, K. A. , Mccomb, C., Patel, R. K., Stevens, K. K., Schneider, M. P., Radjenovic, A. , Morris, S. T.W., Roditi, G. H., Delles, C. and Mark, P. B. (2016) Non-contrast renal magnetic resonance imaging to assess perfusion and corticomedullary differentiation in health and chronic kidney disease. Nephron, 133(3), pp. 183-192. (doi: 10.1159/000447601) (PMID:27362585)
Lindhardt, M. et al. (2016) Proteomic prediction and Renin angiotensin aldosterone system Inhibition prevention Of early diabetic nephRopathy in TYpe 2 diabetic patients with normoalbuminuria (PRIORITY): essential study design and rationale of a randomised clinical multicentre trial. BMJ Open, 6(3), e010310. (doi: 10.1136/bmjopen-2015-010310) (PMID:26936907) (PMCID:PMC4785328)
McCallum, J. E., Mackenzie, A. E., Divorty, N., Clarke, C., Delles, C. , Milligan, G. and Nicklin, S. A. (2016) G protein-coupled receptor 35 mediates human saphenous vein vascular smooth muscle cell migration and endothelial cell proliferation. Journal of Vascular Research, 52(6), pp. 383-395. (doi: 10.1159/000444754) (PMID:27064272) (PMCID:PMC4959467)
Olsen, M. H. et al. (2016) A call to action and a lifecourse strategy to address the global burden of raised blood pressure on current and future generations: the Lancet Commission on hypertension. Lancet, 388(10060), pp. 2665-2712. (doi: 10.1016/S0140-6736(16)31134-5) (PMID:27671667)
Sheikh, A. M., Small, H. Y., Currie, G. and Delles, C. (2016) Systematic review of micro-RNA expression in pre-eclampsia identifies a number of common pathways associated with the disease. PLoS ONE, 11(8), e0160808. (doi: 10.1371/journal.pone.0160808) (PMID:27529341) (PMCID:PMC4986940)
Zhang, Z.-y. et al. (2016) Diastolic left ventricular function in relation to urinary and serum collagen biomarkers in a general population. PLoS ONE, 11(12), e0167582. (doi: 10.1371/journal.pone.0167582) (PMID:27959898) (PMCID:PMC5154519)
2015
Akehurst, C. et al. (2015) Differential expression of microRNA-206 and its target genes in pre-eclampsia. Journal of Hypertension, 33(10), pp. 2068-2074. (doi: 10.1097/HJH.0000000000000656) (PMID:26213997) (PMCID:PMC4570688)
Lindsey, M. L. et al. (2015) Transformative impact of proteomics on cardiovascular health and disease: a scientific statement from the American Heart Association. Circulation, 132(9), pp. 852-872. (doi: 10.1161/CIR.0000000000000226) (PMID:26195497)
Schanstra, J.P. et al. (2015) Diagnosis and prediction of CKD progression by assessment of urinary peptides. Journal of the American Society of Nephrology, 26(8), pp. 1999-2010. (doi: 10.1681/asn.2014050423) (PMID:25589610) (PMCID:PMC4520165)
Dakin, R. S., Parker, A. L., Delles, C. , Nicklin, S. A. and Baker, A. H. (2015) Efficient transduction of primary vascular cells by the rare adenovirus serotype 49 vector. Human Gene Therapy, 26(5), pp. 312-319. (doi: 10.1089/hum.2015.019) (PMID:25760682) (PMCID:PMC4442572)
Fox, C. S. et al. (2015) Future translational applications from the contemporary genomics era: a scientific statement from the American Heart Association. Circulation, 131(19), pp. 1715-1736. (doi: 10.1161/CIR.0000000000000211) (PMID:25882488) (PMCID:PMC4825323)
Ravassa, S., Kuznetsova, T., Varo, N., Thijs, L., Delles, C. , Dominiczak, A. , Díez, J. and Staessen, J. A. (2015) Biomarkers of cardiomyocyte injury and stress identify left atrial and left ventricular remodelling and dysfunction: a population-based study. International Journal of Cardiology, 185, pp. 177-185. (doi: 10.1016/j.ijcard.2015.03.046) (PMID:25796005)
McInnes, I. B. et al. (2015) Effect of interleukin-6 receptor blockade on surrogates of vascular risk in rheumatoid arthritis: MEASURE, a randomised, placebo-controlled study. Annals of the Rheumatic Diseases, 74(4), pp. 694-702. (doi: 10.1136/annrheumdis-2013-204345) (PMID:24368514) (PMCID:PMC4392313)
Mischak, H., Delles, C. , Vlahou, A. and Vanholder, R. (2015) Proteomic biomarkers in kidney disease: issues in development and implementation. Nature Reviews Nephrology, 11(4), pp. 221-232. (doi: 10.1038/nrneph.2014.247) (PMID:25643662)
Brown, C. E. et al. (2015) Urinary proteomic biomarkers to predict cardiovascular events. Proteomics Clinical Applications, 9(5-6), pp. 610-617. (doi: 10.1002/prca.201400195) (PMID:25786980)
Mistry, H.D., Eisele, N., Escher, G., Dick, B., Surbek, D., Delles, C. , Currie, G. , Schlembach, D., Mohaupt, M.G. and Gennari-Moser, C. (2015) Gestation-specific reference intervals for comprehensive spot urinary steroid hormone metabolite analysis in normal singleton pregnancy and 6 weeks postpartum. Reproductive Biology and Endocrinology, 13, 101. (doi: 10.1186/s12958-015-0100-6) (PMID:26337185) (PMCID:PMC4559160)
Musunuru, K. et al. (2015) Basic concepts and potential applications of genetics and genomics for cardiovascular and stroke clinicians: a scientific statement from the American Heart Association. Circulation: Cardiovascular Genetics, 8(1), pp. 216-242. (doi: 10.1161/HCG.0000000000000020) (PMID:25561044) (PMCID:PMC4887701)
2014
Currie, G. , McKay, G. and Delles, C. (2014) Biomarkers in diabetic nephropathy: present and future. World Journal of Diabetes, 5(6), pp. 763-776. 25512779. (doi: 10.4239/wjd.v5.i6.763) (PMID:PMC4265863)
Herbert, A. et al. (2014) Establishing reference values for central blood pressure and its amplification in a general healthy population and according to cardiovascular risk factors. European Heart Journal, 35(44), pp. 3122-3133. (doi: 10.1093/eurheartj/ehu293) (PMID:25112663)
Brown, C.E., O'Sullivan, D., Tennant, S., Dean, J., Murday, V., Oxnard, D., Hailey, H., Rankin, A.C., Tobias, E.S. and Delles, C. (2014) Cascade testing for long QT syndrome in Scotland. Scottish Medical Journal, 59(3), e27. (doi: 10.1177/0036933014540096)
Siwy, J. et al. (2014) Multicentre prospective validation of a urinary peptidome-based classifier for the diagnosis of type 2 diabetic nephropathy. Nephrology Dialysis Transplantation, 29(8), pp. 1563-1570. (doi: 10.1093/ndt/gfu039)
Persu, A. et al. (2014) Eligibility for renal denervation: experience at 11 European expert centers. Hypertension, 63(6), pp. 1319-25. (doi: 10.1161/HYPERTENSIONAHA.114.03194) (PMID:24664290)
Husi, H., Van Agtmael, T. , Mullen, W. , Bahlmann, F. H., Schanstra, J. P., Vlahou, A., Delles, C. , Perco, P. and Mischak, H. (2014) Proteome-based systems biology analysis of the diabetic mouse aorta reveals major changes in fatty acid biosynthesis as potential hallmark in diabetes mellitus-associated vascular disease. Circulation: Cardiovascular Genetics, 7(2), pp. 161-170. (doi: 10.1161/CIRCGENETICS.113.000196)
Tragante, V. et al. (2014) Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple blood-pressure-related loci. American Journal of Human Genetics, 94(3), pp. 349-360. (doi: 10.1016/j.ajhg.2013.12.016) (PMID:24560520) (PMCID:PMC3951943)
Mark, P.B. , Boyle, S., Zimmerli, L.U., McQuarrie, E.P., Delles, C. and Freel, E.M. (2014) Alterations in vascular function in primary aldosteronism - a cardiovascular magnetic resonance imaging study. Journal of Human Hypertension, 28(2), pp. 92-97. (doi: 10.1038/jhh.2013.70)
Carty, D.M., Neisius, U., Rooney, L.K., Dominiczak, A.F. and Delles, C. (2014) Pulse wave analysis for the prediction of preeclampsia. Journal of Human Hypertension, 28(2), pp. 98-104. (doi: 10.1038/jhh.2013.64)
Klein, J., Buffin-Meyer, B., Mullen, W. , Carty, D. M., Delles, C. , Vlahou, A., Mischak, H., Decramer, S., Bascands, J.-L. and Schanstra, J. P. (2014) Clinical proteomics in obstetrics and neonatology. Expert Review of Proteomics, 11(1), pp. 75-89. (doi: 10.1586/14789450.2014.872564)
Denby, L. et al. (2014) MicroRNA-214 antagonism protects against renal fibrosis. Journal of the American Society of Nephrology, 25(1), pp. 65-80. (doi: 10.1681/ASN.2013010072) (PMID:24158985) (PMCID:PMC3871772)
Gillis, K.A. et al. (2014) Inter-study reproducibility of arterial spin labelling magnetic resonance imaging for measurement of renal perfusion in healthy volunteers at 3 Tesla. BMC Nephrology, 15(23), (doi: 10.1186/1471-2369-15-23)
Gu, Y.-M. et al. (2014) The urinary proteome as correlate and predictor of renal function in a population study. Nephrology Dialysis Transplantation, 29(12), pp. 2260-2268. (doi: 10.1093/ndt/gfu234)
Jacobs, L. et al. (2014) Heart 'omics' in AGEing (HOMAGE): design, research objectives and characteristics of the common database. Journal of Biomedical Research, 28(5), pp. 349-359. (doi: 10.7555/JBR.28.20140045) (PMID:25332706) (PMCID:PMC4197385)
Nkuipou-Kenfack, E. et al. (2014) Assessment of metabolomic and proteomic biomarkers in detection and prognosis of progression of renal function in chronic kidney disease. PLoS ONE, 9(5), e96955. (doi: 10.1371/journal.pone.0096955) (PMID:24817014) (PMCID:PMC4016198)
2013
Brown, C.E. et al. (2013) Predictors of QTc and QTc prolongation in the generation scotland family study. Journal of Human Hypertension, 27(10), p. 639. (doi: 10.1038/jhh.2013.72)
Rossi, S. H. et al. (2013) Impaired renal function impacts negatively on vascular stiffness in patients with coronary artery disease. BMC Nephrology, 14(173), (doi: 10.1186/1471-2369-14-173)
Brown, C., Murday, V., Oxnard, D., Anusas, J., Tobias, E.S. , Delles, C. and Findlay, I. (2013) Sudden death referrals to the West of Scotland Inherited Cardiac Conditions Clinic: an overview of findings in probands with a structurally normal heart. Scottish Medical Journal, 58(3), e40-e41. (doi: 10.1177/0036933013495794)
Carty, D.M., Dominiczak, A. and Delles, C. (2013) Pulse wave analysis for prediction of preeclampsia. Endocrine Reviews, 34(3), SAT-520.
Delles, C. (2013) Homocysteine and the very elderly. Journal of Hypertension, 31(5), pp. 874-876. (doi: 10.1097/HJH.0b013e328360aa8b)
Delles, C. and Freel, E.M. (2013) Aldosterone, vascular endothelial growth factor, and preeclampsia: a mystery solved? Hypertension, 61(5), pp. 958-960. (doi: 10.1161/HYPERTENSIONAHA.111.00767)
Baker, A. H. and Delles, C. (2013) Is microRNA-376c a biomarker or mediator of preeclampsia? Hypertension, 61(4), pp. 767-769. (doi: 10.1161/HYPERTENSIONAHA.111.00087)
MacKenzie, R.M. et al. (2013) Mitochondrial reactive oxygen species enhance AMP-activated protein kinase activation in the endothelium of patients with coronary artery disease and diabetes. Clinical Science, 124(6), pp. 403-411. (doi: 10.1042/CS20120239)
Bryce, G.J., Payne, D.J., Gibson, S.C., Byrne, D.S., Delles, C. , McClure, J.D. and Kingsmore, D. (2013) B-type natriuretic peptide predicts postoperative cardiac events and mortality after elective open abdominal aortic aneurysm repair. Journal of Vascular Surgery, 57(2), pp. 345-353. (doi: 10.1016/j.jvs.2012.07.053)
Guo, Y., Lanktree, M. B., Taylor, K. C., Hakonarson, H., Lange, L. A., Keating, B. J., Padmanabhan, S. , Delles, C. , Dominiczak, A. F. and Hastie, C. (2013) Gene-centric meta-analyses of 108 912 individuals confirm known body mass index loci and reveal three novel signals. Human Molecular Genetics, 22(1), pp. 184-201. (doi: 10.1093/hmg/dds396) (PMID:23001569) (PMCID:PMC3522401)
Argiles, A. et al. (2013) CKD273, a new proteomics classifier assessing CKD and its prognosis. PLoS ONE, 8(5), e62837. (doi: 10.1371/journal.pone.0062837) (PMID:23690958) (PMCID:PMC3653906)
Carty, D. M., Schiffer, E. and Delles, C. (2013) Proteomics in hypertension. Journal of Human Hypertension, 27(4), pp. 211-216. (doi: 10.1038/jhh.2012.30) (PMID:22874797)
Currie, G. and Delles, C. (2013) Proteinuria and its relation to cardiovascular disease. International Journal of Nephrology and Renovascular Disease, 7, pp. 13-24. (doi: 10.2147/IJNRD.S40522) (PMID:24379690) (PMCID:PMC3873205)
Delles, C. and Dominiczak, A. F. (2013) Metabolic alterations. In: Mancia, G. (ed.) Resistant Hypertension : Epidemiology, Pathophysiology, Diagnosis and Treatment. Springer, pp. 23-37. ISBN 9788847054158 (doi: 10.1007/978-88-470-5415-8_3)
Husi, H., Sanchez-Niño, M., Delles, C. , Mullen, W. , Vlahou, A., Ortiz, A. and Mischak, H. (2013) A combinatorial approach of Proteomics and Systems Biology in unravelling the mechanisms of acute kidney injury (AKI): involvement of NMDA receptor GRIN1 in murine AKI. BMC Systems Biology, 7(110), (doi: 10.1186/1752-0509-7-110)
White, K. M., Alba, R., Parker, A. L., Wright, A. F., Bradshaw, A. C. , Delles, C. , McDonald, R. A. and Baker, A. H. (2013) Assessment of a novel, capsid-modified adenovirus with an improved vascular gene transfer profile. Journal of Cardiothoracic Surgery, 8(183), (doi: 10.1186/1749-8090-8-183)
2012
Chick, H.E. et al. (2012) Integrase-deficient lentiviral vectors mediate efficient gene transfer to human vascular smooth muscle cells with minimal genotoxic risk. Human Gene Therapy, 23(12), pp. 1247-1257. (doi: 10.1089/hum.2012.042)
MacKenzie, R.M., Sandrim, V.C., Carty, D.M., McClure, J.D. , Freeman, D.J. , Dominiczak, A.F. , McBride, M.W. and Delles, C. (2012) Endothelial FOS expression and pre-eclampsia. BJOG: An International Journal of Obstetrics and Gynaecology, 119(13), pp. 1564-1571. (doi: 10.1111/1471-0528.12016)
Asselbergs, F.W. et al. (2012) Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. American Journal of Human Genetics, 91(5), pp. 823-838. (doi: 10.1016/j.ajhg.2012.08.032)
Mischak, H. et al. (2012) Implementation of proteomic biomarkers: making it work. European Journal of Clinical Investigation, 42(9), pp. 1027-1036. (doi: 10.1111/j.1365-2362.2012.02674.x) (PMID:22519700) (PMCID:PMC3464367)
Hocking, L.J. et al. (2012) Heritability of chronic pain in 2195 extended families. European Journal of Pain, 16(7), pp. 1053-1063. (doi: 10.1002/j.1532-2149.2011.00095.x)
McInnes, I. , Lee, J.S., Thompson, L., Giles, J.T., Bathton, J.M., Salmon, J.E., Beaulieu, A.D., Codding, C.E., Delles, C. and Sattar, N. (2012) The effects of tocilizumab treatment on lipids and inflammatory/prothrombotic markers in patients (pts) with rheumatoid arthritis (RA): data from the randomized, controlled, measure study. European Heart Journal, 33(Sup 1), p. 281. (doi: 10.1093/eurheartj/ehs281)
Bryce, G.J., Payne, C.J., Gibson, S.C., Kingsmore, D.B., Byrne, D.S. and Delles, C. (2012) Risk stratification scores in elective open abdominal aortic aneurysm repair: are they suitable for preoperative decision making? European Journal of Vascular and Endovascular Surgery, 44(1), pp. 55-61. (doi: 10.1016/j.ejvs.2012.03.021)
Delles, C. , Neisius, U. and Carty, D.M. (2012) Proteomics in hypertension and other cardiovascular diseases. Annals of Medicine, 44(S1), S55-S64. (doi: 10.3109/07853890.2012.660494)
Carty, D.M., Anderson, L.A., Freeman, D.J. , Welsh, P.I. , Brennand, J.E., Dominiczak, A.F. and Delles, C. (2012) Early pregnancy soluble E-selectin concentrations and risk of preeclampsia. Journal of Hypertension, 30(5), pp. 954-959. (doi: 10.1097/HJH.0b013e328352573b)
Kane, N. M. et al. (2012) Role of MicroRNAs 99b, 181a, and 181b in the differentiation of human embryonic stem cells to vascular endothelial cells. Stem Cells, 30(4), pp. 643-654. (doi: 10.1002/stem.1026)
Carty, D.M., Anderson, L.A., Duncan, C.N., Baird, D., Rooney, L.K., Dominiczak, A.F. and Delles, C. (2012) Peripheral arterial tone: assessment of microcirculatory function in pregnancy. Journal of Hypertension, 30(1), pp. 117-123. (doi: 10.1097/HJH.0b013e32834d76fb)
Dawson, J. , Walters, M. , Delles, C. , Mischak, H. and Mullen, W. (2012) Urinary proteomics to support diagnosis of stroke. PLoS ONE, 7(5), e35879. (doi: 10.1371/journal.pone.0035879) (PMID:22615742) (PMCID:PMC3353991)
Delles, C. and Padmanabhan, S. (2012) Genetics and hypertension: is it time to change my practice? Canadian Journal of Cardiology, 28(3), pp. 296-304. (doi: 10.1016/j.cjca.2012.02.004)
Neisius, U. et al. (2012) Association of central and peripheral pulse pressure with intermediate cardiovascular phenoytpes. Journal of Hypertension, 30(1), pp. 67-74. (doi: 10.1097/HJH.0b013e32834e12d8)
Neisius, U., Schneider, M.P. and Delles, C. (2012) Association of central and peripheral pulse pressure with intermediate cardiovascular phenotypes Reply. Journal of Hypertension, 30(4), p. 835. (doi: 10.1097/HJH.0b013e328350e57c)
2011
Johnson, T. et al. (2011) Blood pressure loci identified with a gene-centric array. American Journal of Human Genetics, 89(6), pp. 688-700. (doi: 10.1016/j.ajhg.2011.10.013)
Delles, C. , Diez, J. and Dominiczak, A.F. (2011) Urinary proteomics in cardiovascular disease: achievements, limits and hopes. Proteomics Clinical Applications, 5(5-6), pp. 222-232. (doi: 10.1002/prca.201000125)
Ott, C., Schneider, M.P., Delles, C. , Schlaich, M.P., Hilgers, K.F. and Schmieder, R.E. (2011) Association of (pro)renin receptor gene polymorphism with blood pressure in Caucasian men. Pharmacogenetics and Genomics, 21(6), pp. 347-349. (doi: 10.1097/FPC.0b013e328344cdd2)
McQuarrie, E.P., Patel, R.K., Mark, P.B. , Delles, C. , Connell, J., Dargie, H.J., Steedman, T. and Jardine, A.G. (2011) Association between proteinuria and left ventricular mass index: a cardiac MRI study in patients with chronic kidney disease. Nephrology Dialysis Transplantation, 26(3), pp. 933-938. (doi: 10.1093/ndt/gfq418)
Stevens, K.K., Morgan, I.R., Patel, R.K., Geddes, C.C., Mark, P.B. , Jardine, A.G. and Delles, C. (2011) Serum phosphate and outcome at one year after deceased donor renal transplantation. Clinical Transplantation, 25(2), E199-E204. (doi: 10.1111/j.1399-0012.2011.01400.x)
Lanktree, M. B. et al. (2011) Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height. American Journal of Human Genetics, 88(1), pp. 6-18. (doi: 10.1016/j.ajhg.2010.11.007)
Carty, D.M. et al. (2011) Urinary proteomics for prediction of preeclampsia. Hypertension, 57(3), pp. 561-569. (doi: 10.1161/HYPERTENSIONAHA.110.164285)
Mullen, W. , Delles, C. and Mischak, H. (2011) Urinary proteomics in the assessment of chronic kidney disease. Current Opinion in Nephrology and Hypertension, 20(6), pp. 654-661. (doi: 10.1097/MNH.0b013e32834b7ffa)
Mullen, W. , Gonzalez, J., Siwy, J., Franke, J., Sattar, N. , Mullan, A., Roberts, S., Delles, C. , Mischak, H. and Albalat, A. (2011) A pilot study on the effect of short-term consumption of a polyphenol rich drink on biomarkers of coronary artery disease defined by urinary proteomics. Journal of Agricultural and Food Chemistry, 59(24), pp. 12850-12857. (doi: 10.1021/jf203369r) (PMID:22070129)
Ott, C., Schneider, M. P., Delles, C. , Schlaich, M. P. and Schmieder, R. E. (2011) Reduction in Basal Nitric Oxide Activity Causes Albuminuria. Diabetes, 60(2), pp. 572-576. (doi: 10.2337/db09-1630)
2010
Good, D. M. et al. (2010) Naturally Occurring Human Urinary Peptides for Use in Diagnosis of Chronic Kidney Disease. Molecular and Cellular Proteomics, 9(11), pp. 2424-2437. (doi: 10.1074/mcp.M110.001917)
Carty, D.M., Delles, C. and Dominiczak, A.F. (2010) Preeclampsia and future maternal health. Journal of Hypertension, 28(7), pp. 1349-1355. (doi: 10.1097/HJH.0b013e32833a39d0)
Delles, C. (2010) Angiotensinogen, birth weight and diabetes: will genetics provide a link? Journal of Hypertension, 28(4), pp. 665-667. (doi: 10.1097/HJH.0b013e328337f524)
Delles, C. , Dymott, J.A., Neisius, U., Rocchiccioli, J.P., Bryce, G.J., Moreno Zulategui, M.U., Carty, D.M., Berg, G.A., Hamilton, C.A. and Dominiczak, A.F. (2010) Reduced LDL-cholesterol levels in patients with coronary artery disease are paralelled by improved endothelial function: An observational study in patients from 2003 and 2007. Atherosclerosis, 211(1), pp. 271-277. (doi: 10.1016/j.atherosclerosis.2010.01.014)
Delles, C. and Jardine, A.G. (2010) Renal function and cardiovascular events: relevance of eGFR and albuminuria in patients with diabetes. Diabetologia, 54(1), pp. 4-6. (doi: 10.1007/s00125-010-1942-2)
Delles, C. , McBride, M.W. , Graham, D. , Padmanabhan, S. and Dominiczak, A.F. (2010) Genetics of hypertension: from experimental animals to humans. Biochimica et Biophysica Acta: Molecular Basis of Disease, 1802(12), pp. 1299-1308. (doi: 10.1016/j.bbadis.2009.12.006)
Delles, C. et al. (2010) Urinary proteomic diagnosis of coronary artery disease: identification and clinical validation in 623 individuals. Journal of Hypertension, 28(11), pp. 2316-2322. (doi: 10.1097/HJH.0b013e32833d81b7)
Delles, C. and Dominiczak, A. F. (2010) Redox-related genetic markers of cardiovascular diseases. In: Sauer, H., Shah, A.M. and Laurindo, F.R.M. (eds.) Studies on Cardiovascular Disorders. Series: Oxidative stress in applied basic research and clinical practice. Humana Press, pp. 187-209. ISBN 9781607615996 (doi: 10.1007/978-1-60761-600-9_10)
Dominiczak, A. F. et al. (2010) Systems biology to battle vascular disease. Nephrology Dialysis Transplantation, 25(4), pp. 1019-1022. (doi: 10.1093/ndt/gfq025)
Maahs, D.M. et al. (2010) Urinary collagen fragments are significantly altered in diabetes: a link to pathophysiology. PLoS ONE, 5(9), e13051. (doi: 10.1371/journal.pone.0013051) (PMID:20927192) (PMCID:PMC2946909)
Mischak, H., Delles, C. , Klein, J. and Schanstra, J.P. (2010) Urinary Proteomics Based on Capillary Electrophoresis-Coupled Mass Spectrometry in Kidney Disease: Discovery and Validation of Biomarkers, and Clinical Application. Advances in Chronic Kidney Disease, 17(6), pp. 493-506. (doi: 10.1053/j.ackd.2010.09.004)
Padmanabhan, S. et al. (2010) Genome-wide association study of blood pressure extremes identifies variant near UMOD associated with hypertension. PLoS Genetics, 6(10), e1001177. (doi: 10.1371/journal.pgen.1001177)
Padmanabhan, S. et al. (2010) The effects of sex and method of blood pressure measurement on genetic associations with blood pressure in the PAMELA study. Journal of Hypertension, 28(3), pp. 465-477. (doi: 10.1097/HJH.0b013e32833594d7)
Taurino, C., Miller, W.H. , McBride, M.W. , McClure, J.D. , Khanin, R., Moreno Zulategui, M.U., Dymott, J., Delles, C. and Dominiczak, A.F. (2010) Gene expression profiling in whole blood of patients with coronary artery disease. Clinical Science, 119(8), pp. 335-343. (doi: 10.1042/CS20100043)
2009
Talmud, P. et al. (2009) Gene-centric association signals for lipids and apolipoproteins identified via the humanCVD BeadChip. American Journal of Human Genetics, 85(5), pp. 628-642. (doi: 10.1016/j.ajhg.2009.10.014)
Dominiczak, A. F. , Delles, C. and Padmanabhan, S. (2009) Are isolated populations better for studying genes that predispose to hypertension? Journal of Hypertension, 27(5), pp. 939-940. (doi: 10.1097/HJH.0b013e328329fca3) (PMCID:PMC2709222)
2008
Delles, C. (2008) Risk factors and target organ damage: is there a special case for prehypertension? Journal of Hypertension, 26(12), pp. 2268-2270. (doi: 10.1097/HJH.0b013e328317f039)
Delles, C., McBride, M.W., Padmanabhan, S. and Dominiczak, A.F. (2008) The genetics of cardiovascular disease. Trends in Endocrinology and Metabolism, 19(9), pp. 309-316. (doi: 10.1016/j.tem.2008.07.010)
Delles, C., Raff, U., Mimran, A., Fauvel, J.P., Ruilope, L.M. and Schmieder, R.E. (2008) Effects of telmisartan and ramipril on adiponectin and blood pressure in patients with type 2 diabetes. American Journal of Hypertension, 21(12), pp. 1330-1336. (doi: 10.1038/ajh.2008.297)
Jantos-Siwy, J., Schiffer, E., Brand, K., Schumann, G., Rossing, K., Delles, C. , Mischak, H. and Metzger, J. (2008) Quantitative urinary proteome analysis for biomarker evaluation in chronic kidney disease. Journal of Proteome Research, 8(1), pp. 268-281. (doi: 10.1021/pr800401m) (PMID:19012428)
Ritt, M., Ott, C., Delles, C. , Schneider, M.P. and Schmieder, R.E. (2008) Impact of the endothelial nitric oxide synthase gene G894T polymorphism on renal endothelial function in patients with type 2 diabetes. Pharmacogenetics and Genomics, 18(8), pp. 699-707.
Delles, C. et al. (2008) Glutathione S-transferase variants and hypertension. Journal of Hypertension, 26(7), pp. 1343-1352. (doi: 10.1097/HJH.0b013e3282fe1d67)
Padmanabhan, S. , Melander, O., Hastie, C., Menni, C., Delles, C. , Connell, J. M. and Dominiczak, A. F. (2008) Hypertension and genome-wide association studies: combining high fidelity phenotyping and hypercontrols. Journal of Hypertension, 26(7), pp. 1275-1281. (doi: 10.1097/HJH.0b013e3282ff634f)
Delles, C. , Zimmerli, L., McGrane, D. J., Koh-Tan, C. H.H., Pathi, V. L., McKay, A. J., Steedman, T., Dargie, H. J., Hamilton, C. A. and Dominiczak, A. F. (2008) Vascular stiffness is related to superoxide generation in the vessel wall. Journal of Hypertension, 26(5), pp. 946-955.
Berry, C., Zimmerli, L.U., Steedman, T., Foster, J.E., Dargie, H.J., Berg, H.A., Dominiczak, A.F. and Delles, C. (2008) Cardiac magnetic resonance findings predict increased resource utilization in elective coronary artery bypass grafting. Clinical Science, 114(6), pp. 423-430. (doi: 10.1042/CS20070337)
Zimmerli, L.U. et al. (2008) Urinary proteomic biomarkers on coronary artery disease. Molecular and Cellular Proteomics, 7(2), pp. 290-298. (doi: 10.1074/mcp.M700394-MCP200)
Carty, D., Delles, C. and Dominiczak, A. (2008) Novel Biomarkers for Predicting Preeclampsia. Trends in Cardiovascular Medicine, 18(5), pp. 186-194. (doi: 10.1016/j.tcm.2008.07.002)
Delles, C. (2008) Candidate gene studies in cardiovascular medicine: complex diseases and even more complex intermediate phenotypes. Journal of Hypertension, 26(6), pp. 1069-1071.
Delles, C. , Miller, W. H. and Dominiczak, A. F. (2008) Targeting reactive oxygen species in hypertension. Antioxidants and Redox Signaling, 10(6), pp. 1061-1077. (doi: 10.1089/ars.2007.2008)
Dymott, J.A., Chow, C., Rocchiccioli, J.P., Berg, G.A., Cherry, A.K.L., Delles, C. , Hamilton, C.A. and Dominiczak, A.F. (2008) Endothelial function in patients undergoing coronary artery by-pass grafting is improved in patients in 2006 compared to 2003. Scottish Medical Journal, 53(1), p. 57.
Schneider, M. P., Delles, C. , Klingbeil, A. U., Ludwig, M., Kolloch, R. E., Krekler, M., Stumpe, K. O. and Schmieder, R. E. (2008) Effect of angiotensin receptor blockade on central haemodynamics in essential hypertension: results of a randomised trial. Journal of the Renin-Angiotensin-Aldosterone System, 9(1), pp. 49-56. (doi: 10.3317/jraas.2008.003) (PMID:18404609)
2007
Delles, C. (2007) Mitochondria, maternal transmission and hypertension. Journal of Hypertension, 25(10), pp. 2001-2003. (doi: 10.1097/HJH.0b013e3282ef6cfa)
Delles, C. (2007) Vascular function in rheumatoid arthritis: intermediate phenotypes and cardiovascular risk. Journal of Hypertension, 25(6), pp. 1195-1196. (doi: 10.1097/HJH.0b013e3280dd8a77)
Schlaich, M.P., Oehmer, S., Schneider, M.P., Delles, C. , Schmidt, B.M.W. and Schmieder, R.E. (2007) Effects of nitric oxide synthase inhibition and L-arginine on renal haemodynamics in young patients at high cardiovascular risk. Atherosclerosis, 192(1), pp. 155-160. (doi: 10.1016/j.atherosclerosis.2006.04.025)
Schmieder, R., Delles, C. , Mimran, A., Fauvel, J. and Ruilope, L. (2007) Impact of telmisartan versus ramipri on ronal endothelial function in patients with hypertension and type 2 diabetes. Diabetes Care, 30(6), pp. 1351-1356. (doi: 10.2337/dc06-1551)
Zimmerli, L., Mark, P., Steedman, T., Foster, J., Berg, G., Dargie, H., Jardine, A., Delles, C. and Dominiczak, A. (2007) Vascular function in patients with end-stage renal disease and/or coronary artery disease: A cardiac magnetic resonance imaging study. Kidney International, 71(1), pp. 68-73. (doi: 10.1038/sj.ki.5002024)
2006
Al Benna, S., Hamilton, C.A., McClure, J.D. , Rogers, P.N., Berg, G.A., Ford, I. , Delles, C. and Dominiczak, A.F. (2006) Low-density lipoprotein cholesterol determines oxidative stress and endothelial dysfunction in saphenous veins from patients with coronary artery disease. Arteriosclerosis, Thrombosis, and Vascular Biology, 26(1), pp. 218-223. (doi: 10.1161/01.ATV.0000193626.22269.45)
Delles, C. and Dominiczak, A. (2006) Vascular failure or sick vessel syndrome: The cardiovascular continuum is a useful concept for clinical research. Journal of Hypertension, 24(11), pp. 2147-2148. (doi: 10.1097/01.hjh.0000249687.43123.d2)
McBride, M. , Graham, D., Delles, C. and Dominiczak, A. (2006) Functional genomics in hypertension. Current Opinion in Nephrology and Hypertension, 15(2), pp. 145-151. (doi: 10.1097/01.mnh.0000203188.57513.3f)
Michelson, G., Warntges, S., Harazny, J., Oehmer, S., Delles, C. and Schmieder, R.E. (2006) Effect of NOS inhibition on retinal arterial and capillary circulation in early arterial hypertension. Retina: The Journal of Retinal and Vitreous Diseases, 26(4), pp. 437-444. (doi: 10.1097/01.iae.0000238550.74626.e5)
Oehmer, S., Harazny, J., Delles, C. , Schwarz, T., Handrock, R., Michelson, G. and Schmieder, R. (2006) Valsartan and retinal endothelial function in elderly hypertensive patients. Blood Pressure, 15(3), pp. 185-191. (doi: 10.1080/08037050600772680)
Schaufele, T., Schlaich, M., Delles, C. , Klingbeil, A., Fleischmann, E. and Schmieder, R. (2006) Impaired basal NO activity in patients with glomerular disease and the influence of oxidative stress. Kidney International, 70(6), pp. 1177-1181. (doi: 10.1038/sj.ki.5001745)
Schmidt, B., Sammer, U., Fleischmann, I., Schlaich, M., Delles, C. and Schmieder, R. (2006) Rapid nongenomic effects of aldosterone on the renal vasculature in humans. Hypertension, 47(4), pp. 650-655. (doi: 10.1161/01.HYP.0000205224.58715.cc)
2005
Schneider, M.P., Delles, C. , Schmidt, B.M.W., Oehmer, S., Schwarz, T.K., Schmieder, R.E. and John, S. (2005) Superoxide scavenging effects of N-acetylcysteine and vitamin C in subjects with essential hypertension. American Journal of Hypertension, 18(8), pp. 1111-1117. (doi: 10.1016/j.amjhyper.2005.02.006)
John, S., Schneider, M.P., Delles, C. , Jacobi, J. and Schmieder, R.E. (2005) Lipid-independent effects of statins on endothelial function and bioavailability of nitric oxide in hypercholesterolemic patients. American Heart Journal, 149(3), 473.e1-473.e10. (doi: 10.1016/j.ahj.2004.06.02)
Dominiczak, A. F., Graham, D. , McBride, M. W. , Brain, N. J.R., Lee, W. K. , Charchar, F. J., Tomaszewski, M., Delles, C. and Hamilton, C. A. (2005) Corcoran Lecture. Cardiovascular genomics and oxidative stress. Hypertension, 45(4), pp. 636-642. (doi: 10.1161/01.HYP.0000154253.53134.09)
Schmieder, R., Klingbeil, A., Fleischmann, E., Veelken, R. and Delles, C. (2005) Additional antiproteinuric effect of ultrahigh dose candesartan: A double-blind, randomized, prospective study. Journal of the American Society of Nephrology, 16(10), pp. 3038-3045. (doi: 10.1681/ASN.2005020138)
2004
Delles, C., Klingbeil, A.U., Schneider, M.P., Handrock, R., Schaufele, T. and Schmieder, R.E. (2004) The role of nitric oxide in the regulation of glomerular haemodynamics in humans. Nephrology Dialysis Transplantation, 19(6), pp. 1392-1397. (doi: 10.1093/ndt/gfh187)
Delles, C., Schluter, C., Wittmann, M., Renders, L., Riess, R., Rosch, W., Schott, G., Rupprecht, H. and Kunzendorf, U. (2004) 'Very delayed' graft function in a patient after living related kidney transplantation: A case report. Transplantation Proceedings, 36(5), pp. 1377-1379. (doi: 10.1016/j.transproceed.2004.05.015)
Delles, C., Schluter, C., Wittmann, M., Renders, L., Riess, R., Rosch, W., Schott, G., Rupprecht, H. and Kunzendorf, U. (2004) "Very delayed" graft function in a patient after living related kidney transplantation: A case report. Transplantation Proceedings, 36, pp. 1377-1379. (doi: 10.1016/j.transproceed.2004.05.015)
Delles, C. and Schmieder, R. (2004) Effects of the angiotensin-1 receptor blocker valsartan compared with amlodipine on renal hemodynamics - Reply. American Journal of Hypertension, 17(7), pp. 639-640.
Delles, C. and Schmieder, R. (2004) Is the afferent arteriole the main location of nitric oxide action and synthesis in humans? Reply. Nephrology Dialysis Transplantation, 19(11), pp. 2925-2926.
Delles, C. and Schmieder, R. (2004) Renal endothelial effects of anti hypertensive therapy. Current Opinion in Nephrology and Hypertension, 13(5), pp. 489-493.
Delles, C. , Michelson, G., Harazny, J., Oehmer, S., Hilgers, K.F. and Schmieder, R.E. (2004) Impaired endothelial function of the retinal vasculature in hypertensive patients. Stroke, 35(6), pp. 1289-1293. (doi: 10.1161/01.STR.0000126597.11534.3b)
Delles, C. , Schneider, M., Oehmer, S., Fleischmann, I., Fleischmann, E.F. and Schmeider, R.E. (2004) Increased response of renal perfusion to the antioxidant vitamin C in type 2 diabetes. Nephrology Dialysis Transplantation, 19(10), pp. 2513-2518. (doi: 10.1093/ndt/gfh405)
Fleischmann, E.H., John, S., Delles, C. , Schneider, M.P., Schmidt, B.M.W. and Schmieder, R.E. (2004) The effect of statins on angiotensin II-induced hemodynamic changes in young, mildly hypercholesterolemic men. American Journal of Hypertension, 17(12), pp. 1120-1126. (doi: 10.1016/j.amjhyper.2004.07.011)
Schneider, M.P., Klingbeil, A.U., Delles, C., Ludwig, M., Kolloch, R.E., Krekler, M., Stumpe, K.O. and Schmieder, R.E. (2004) Effect of irbesartan versus atenolol on left ventricular mass and voltage: results of the Cardio Vascular Irbesartan Project. Hypertension, 44(1), pp. 61-66. (doi: 10.1161/01.HYP.0000133249.28773.d7)
2003
Delles, C. , Klingbeil, A.U., Schneider, M.P., Handrock, R., Schmieder, R.E. and Weidinger, G. (2003) Direct comparison of the effects of valsartan and amlodipine on renal hemodynamics in human essential hypertension. American Journal of Hypertension, 16(12), pp. 1030-1035. (doi: 10.1016/j.amjhyper.2003.07.017)
Schneider, M.P., Klingbeil, A.U., Delles, C. , Schmidt, B.M.W., John, S. and Schmieder, R.E. (2003) Vitamin C augments the renal response to L-arginine in smokers. Nephrology Dialysis Transplantation, 18(8), pp. 1512-1517. (doi: 10.1093/ndt/gfg195)
Delles, C. , Schneider, M.P., Oehmer, S., Fleischmann, E.H. and Schmieder, R.E. (2003) L-arginine-induced vasodilation of the renal vasculature is not altered in hypertensive patients with type 2 diabetes. Diabetes Care, 26(6), pp. 1836-1840. (doi: 10.2337/diacare.26.6.1836)
Schneider, M.P., Delles, C. , Fleischmann, E., Schmidt, B.M.W., John, S. and Schmieder, R.E. (2003) Effect of elevated triglyceride levels on endothelium-dependent vasodilation in patients with hypercholesterolemia. American Journal of Cardiology, 91(4), pp. 482-484. (doi: 10.1016/S0002-9149(02)03255-1)
Delles, C. , Schmidt, B., Muller, H., Oehmer, S., Klingbeil, A. and Schmieder, R. (2003) Functional relevance of aldosterone for the determination of left ventricular mass. American Journal of Cardiology, 91(3), pp. 297-301. (doi: 10.1016/S0002-9149(02)03158-2)
Delles, C. and Schmieder, R. (2003) Endothelial function of the human renal vasculature. Deutsche Medizinische Wochenschrift, 128(3), pp. 92-96.
Schmidt, B.M.W., Oehmer, S., Delles, C. , Bratke, R., Schneider, M.P., Klingbeil, A., Fleischmann, E.H. and Schmieder, R.E. (2003) Rapid nongenomic effects of aldosterone on human forearm vasculature. Hypertension, 42(2), pp. 156-160. (doi: 10.1161/01.HYP.0000083298.23119.16)
Schneider, M.P., Hilgers, K.F., Huang, Y., Delles, C. , John, S., Oehmer, S. and Schmieder, R.E. (2003) The C242T p22phox polymorphism and endothelium-dependent vasodilation in subjects with hypercholesterolaemia. Clinical Science, 105(1), pp. 97-103. (doi: 10.1042/CS20030003)
2002
Schlaich, M.P., Klingbeil, A.U., Jacobi, J., Delles, C. , Schneider, M.P., Schmidt, B.M. and Schmieder, R.E. (2002) Altered aldosterone response to salt intake and angiotensin II infusion in young normotensive men with parental history of arterial hypertension. Journal of Hypertension, 20(1), pp. 117-24.
Delles, C. , Jacobi, J., John, S., Fleischmann, I. and Schmieder, R. (2002) Effects of enalapril and eprosartan on the renal vascular nitric oxide system in human essential hypertension. Kidney International, 61(4), pp. 1462-1468. (doi: 10.1046/j.1523-1755.2002.00260.x)
Delles, C. , Jacobi, J., Schlaich, M., John, S. and Schmieder, R. (2002) Assessment of endothelial function of the renal vasculature in human subjects. American Journal of Hypertension, 15(1), pp. 3-9. (doi: 10.1016/S0895-7061(01)02242-7)
Delles, C. , Schneider, M., John, S., Gekle, M. and Schmieder, R. (2002) Angiotensin converting enzyme inhibition and angiotensin II AT(1)-receptor blockade reduce the levels of asymmetrical N-G, N-G-dimethylarginine in human essential hypertension. American Journal of Hypertension, 15(7), pp. 590-593. (doi: 10.1016/S0895-7061(02)02278-1)
Delles, C. , Weidner, S., Schobel, H. and Rupprecht, H. (2002) Renal-artery stenosis in a patient with Takayasu's arteritis. Nephrology Dialysis Transplantation, 17(7), pp. 1339-1341. (doi: 10.1093/ndt/17.7.1339)
Delles, C. , Wittmann, M., Renders, L., Kunzendorf, U., Bohner, C., Wutke, R., Lang, W., Schott, G. and Rupprecht, H. (2002) Restoration of renal allograft function by endovascular stenting of an iliac artery dissection. Nephrology Dialysis Transplantation, 17(6), pp. 1116-1118. (doi: 10.1093/ndt/17.6.1116)
2001
Zeltner, R., Delles, C. , Schneider, M., Siffert, W. and Schmieder, R.E. (2001) G-protein beta(3) subunit gene (GNB3) 825T allele is associated with enhanced renal perfusion in early hypertension. Hypertension, 37(3), pp. 882-886. (doi: 10.1161/01.HYP.37.3.882)
Delles, C. , Erdmann, J., Jacobi, J., Hilgers, K., Fleck, E., Regitz-Zagrosek, V. and Schmieder, R. (2001) Aldosterone synthase (CYP11B2)-344 C/T polymorphism is associated with left ventricular structure in human arterial hypertension. Journal of the American College of Cardiology, 37(3), pp. 878-884. (doi: 10.1016/S0735-1097(00)01174-8)
Delles, C. and Schmieder, R. (2001) The kidney in congestive heart failure: Renal adverse event rate of treatment. Journal of Cardiovascular Pharmacology, 38(1), pp. 99-107.
Hilgers, K., Delles, C. , Veelken, R. and Schmieder, R. (2001) Angiotensinogen gene core promoter variants and non-modulating hypertension. Hypertension, 38(6), pp. 1250-1254. (doi: 10.1161/hy1201.096545)
John, S., Delles, C., Jacobi, J., Schlaich, M.P., Schneider, M., Schmitz, G. and Schmieder, R.E. (2001) Rapid improvement of nitric oxide bioavailability after lipid-lowering therapy with cerivastatin within two weeks. Journal of the American College of Cardiology, 37(5), pp. 1351-1358. (doi: 10.1016/S0735-1097(01)01128-7)
Leidig, M., Delles, C. , Kuchenbecker, C., Lederle, X., Weidinger, G. and Schmieder, R. (2001) Pharmacokinetics of valsartan in hypertensive patients on long-term haemodialysis. Clinical Drug Investigation, 21(1), pp. 59-66. (doi: 10.2165/00044011-200121010-00008)
Schmieder, R., Erdmann, J., Delles, C. , Jacobi, J., Fleck, E., Hilgers, K. and Regitz-Zagrosek, V. (2001) Effect of the angiotensin II type 2-receptor gene (+1675 G/A) on left ventricular structure in humans. Journal of the American College of Cardiology, 37(1), pp. 175-182. (doi: 10.1016/S0735-1097(00)01063-9)
Schneider, M., Erdmann, J., Delles, C. , Fleck, E., Regitz-Zagrosek, V. and Schmieder, R. (2001) Functional gene testing of the Glu298Asp polymorphism of the endothelial nitric oxide synthase - Reply. Journal of Hypertension, 19(7), pp. 1341-1342.
Veelken, R., Delles, C. , Hilgers, K. and Schmieder, R. (2001) Outcome survey in unselected hypertensive patients with type 2 diabetes mellitus: effects of ACE inhibition. American Journal of Hypertension, 14(7), pp. 672-678. (doi: 10.1016/S0895-7061(01)01300-0)
Articles
Greenlees, C., Hosseinzadeh, S., Delles, C. and Mcginnigle, E. (2024) Hypertension evaluation and management in new young patients: are we doing our female patients a disservice? Blood Pressure, 33(1), 2387909. (doi: 10.1080/08037051.2024.2387909) (PMID:39102372)
Dieden, A. et al. (2024) Proteomic biomarkers and pathway analysis for progression to heart failure in three epidemiological representative cohorts. European Journal of Heart Failure, (doi: 10.1002/ejhf.3502) (PMID:39466935) (Early Online Publication)
Dieden, A. et al. (2024) Proteomic biomarkers and pathway analysis for progression to heart failure in three epidemiological representative cohorts. European Journal of Heart Failure, (Accepted for Publication)
Ho, F. et al. (2024) Maternal and pregnancy factors contributing to the association between area deprivation and infant mortality in England: a retrospective cohort study. Lancet Regional Health Europe, (doi: 10.1016/j.lanepe.2024.101075) (In Press)
Zhou, M., Mary, S. , Delles, C. , Padmanabhan, S. , Graham, D. , McBride, M. W. and Dominiczak, A. (2024) Insights into uromodulin and blood pressure. Current Hypertension Reports, (doi: 10.1007/s11906-024-01317-0) (PMID:39259220) (Early Online Publication)
Delles, C. , Setjiadi, D. and Geddes, C. (2024) Blood pressure measurement technique in clinical practice. Research Square, (doi: 10.21203/rs.3.rs-4635130/v1)
Kulkarni, S. et al. (2024) Investigation and management of young-onset hypertension: British and Irish Hypertension Society position statement. Journal of Human Hypertension, (doi: 10.1038/s41371-024-00922-5) (PMID:38942895) (Early Online Publication)
Padmanabhan, S. , Delles, C. and Dominiczak, A. F. (2024) Beyond genome-wide scans: advancing hypertension genomics into the future. Hypertension, 81(6), pp. 1186-1189. (doi: 10.1161/HYPERTENSIONAHA.124.21371) (PMID:38748763)
Docherty, N. G., Delles, C. and López-Hernández, F. J. (2024) Reframing acute kidney injury as a pathophysiological continuum of disrupted renal excretory function. Acta Physiologica, (doi: 10.1111/apha.14181) (PMID:38808913) (Early Online Publication)
Kobayashi, M. et al. (2024) Proteomic profiles of left atrial volume and its influence on response to spironolactone: findings from the HOMAGE trial and STANISLAS cohort. European Journal of Heart Failure, 26(5), pp. 1231-1241. (doi: 10.1002/ejhf.3202) (PMID:38528728)
Lim, M. W. S., Lucas-Herald, A. K. , Mason, A., Delles, C. and Connelly, P. J. (2024) Sex differences in the cardiovascular effects of GnRH analogues. Journal of Endocrinology, 261(1), e230309. (doi: 10.1530/JOE-23-0309) (PMID:38265843)
Rossitto, G., Bertoldi, G., Rutkowski, J. M., Mitchell, B. M. and Delles, C. (2024) Sodium, interstitium, lymphatics, and hypertension - A tale of hydraulics. Hypertension, 81(4), pp. 727-737. (doi: 10.1161/HYPERTENSIONAHA.123.17942) (PMID:38385255)
Sani, R. N., Connelly, P. J. , Toft, M., Rowa-Dewar, N., Delles, C. , Gasevic, D. and Karaye, K. M. (2024) Rural-urban difference in the prevalence of hypertension in West Africa: a systematic review and meta-analysis. Journal of Human Hypertension, 38, pp. 352-364. (doi: 10.1038/s41371-022-00688-8) (PMID:35430612) (PMCID:PMC11001577)
Mavrogeorgis, E. et al. (2024) Multiple urinary peptides are associated with hypertension: a link to molecular pathophysiology. Journal of Hypertension, (doi: 10.1097/HJH.0000000000003726) (PMID:38690919) (Early Online Publication)
Bosserdt, M. et al. (2024) Age and computed tomography and invasive coronary angiography in stable chest pain: a prespecified secondary analysis of the discharge randomized clinical trial. JAMA Cardiology, 9(4), pp. 346-356. (doi: 10.1001/jamacardio.2024.0001) (PMID:38416472)
Olowoyo, P. et al. (2024) Priorities to reduce the burden of hypertension in Africa through ACHIEVE. Lancet Global Health, 12(2), e192-e193. (doi: 10.1016/S2214-109X(23)00540-5) (PMID:38245107)
Mary, S. et al. (2024) Pregnancy-associated changes in urinary uromodulin excretion in chronic hypertension. Journal of Nephrology, (doi: 10.1007/s40620-023-01830-6) (PMID:38236469) (Early Online Publication)
Kharlamov, A., Sherriff, N., Delles, C. and van der Harst, P. (2024) Tackling cardiovascular healthcare disparities for LGBTQIA+ population: a call to action in the European Society of Cardiology. European Heart Journal, (doi: 10.1093/eurheartj/ehad882) (PMID:38195053) (Early Online Publication)
Bagordo, D., Rossi, G. P., Delles, C. , Wiig, H. and Rossitto, G. (2023) The tangram of sodium and fluid balance: salt series. Hypertension, (doi: 10.1161/HYPERTENSIONAHA.123.19569) (Early Online Publication)
Neupane, D. et al. (2023) Emerging Authors Program for building cardiovascular disease prevention and management research capacity in low- and middle-income countries: a collaboration of the U.S. Centers for Disease Control and Prevention, the Lancet Commission on Hypertension Group, Resolve to Save Lives, and the World Hypertension League. Journal of Human Hypertension, -023. (doi: 10.1038/s41371-023-00880-4) (Early Online Publication)
Connelly, P. , Osmanska, J., Lee, M. M.Y. , Delles, C. , McEntegart, M. B. and Byrne, J. (2023) A case report of myocardial infarction in a young transgender man with testosterone therapy? raising awareness on healthcare issues in the transgender community and a call for further research. European Heart Journal: Case Reports, 7(12), ytad562. (doi: 10.1093/ehjcr/ytad562) (PMID:38093823) (PMCID:PMC10716680)
Desson, Z. et al. (2023) Improving the accuracy of blood pressure measuring devices in Australia: a modelled return on investment study. Journal of Human Hypertension, (doi: 10.1038/s41371-023-00866-2) (PMID:37938294) (Early Online Publication)
Murphy, C. N., Delles, C. , Davies, E. and Connelly, P. J. (2023) Cardiovascular disease in transgender individuals. Atherosclerosis, 384, 117282. (doi: 10.1016/j.atherosclerosis.2023.117282) (PMID:37821271)
de Beer, D., MC. Mels, C., Schutte, A., Delles, C. , Mary, S. , Mullen, W. , Mischak, H. and Kruger, R. (2023) Urinary peptidomics and pulse wave velocity: The African-PREDICT study. Journal of Proteome Research, 22(10), pp. 3282-3289. (doi: 10.1021/acs.jproteome.3c00347) (PMID:37688558) (PMCID:PMC10563154)
Mangion, K. et al. (2023) Post-COVID-19 illness and associations with sex and gender. BMC Cardiovascular Disorders, 23, 389. (doi: 10.1186/s12872-023-03412-7) (PMID:37553628) (PMCID:PMC10408208)
Brown, C. E., Casey, H., Dominiczak, A. F. , Kerr, S., Campbell, A. and Delles, C. (2023) Impact of preeclampsia on cardiovascular events: an analysis of the Generation Scotland: Scottish family health study. Journal of Human Hypertension, 37(8), pp. 735-741. (doi: 10.1038/s41371-023-00812-2) (PMID:36973315)
Casey, H., Dennehy, N., Fraser, A., Lees, C., McEniery, C. M., Scott, K. , Wilkinson, I. B. and Delles, C. (2023) Placental syndromes and maternal cardiovascular health. Clinical Science, 137(16), pp. 1211-1224. (doi: 10.1042/CS20211130) (PMID:37606085)
Connelly, P. J. and Delles, C. (2023) Journal of Human Hypertension special issue on sex and gender differences in hypertension. Journal of Human Hypertension, 37(8), pp. 587-588. (doi: 10.1038/s41371-023-00847-5) (PMID:37474602)
Angelov, A., Connelly, P. J. , Delles, C. and Kararigas, G. (2023) Sex-biased and sex hormone-dependent regulation of apolipoprotein A1. Current Opinion in Physiology, 33, 100654. (doi: 10.1016/j.cophys.2023.100654)
De Beer, D., Mels, C. M.C., Schutte, A. E., Delles, C. , Mary, S. , Mullen, W. , Latosinska, A., Mischak, H. and Kruger, R. (2023) Identifying a urinary peptidomics profile for hypertension in young adults: the African-PREDICT study. Proteomics, 23(11), 2200444. (doi: 10.1002/pmic.202200444) (PMID:36943111)
Arisido, M. W. et al. (2023) Cluster analysis of angiotensin biomarkers to identify antihypertensive drug treatment in population studies. BMC Medical Research Methodology, 23, 131. (doi: 10.1186/s12874-023-01930-8) (PMID:37245005) (PMCID:PMC10224304)
Girerd, N. et al. (2023) Protein biomarkers of new-onset heart failure: insights from the Heart Omics and Ageing cohort, the Atherosclerosis Risk in Communities Study, and the Framingham Heart Study. Circulation: Heart Failure, 16(5), pp. 426-441. (doi: 10.1161/CIRCHEARTFAILURE.122.009694) (PMID:37192292) (PMCID:PMC10179982)
Wang, Y. et al. (2023) Early-life cardiovascular risk factor trajectories and vascular aging in midlife: a 30-year prospective cohort study. Hypertension, 80(5), pp. 1057-1066. (doi: 10.1161/HYPERTENSIONAHA.122.20518) (PMID:36880389)
Degenaar, A., Jacobs, A., Kruger, R., Delles, C. , Mischak, H. and Mels, C.M.C. (2023) Cardiovascular risk and kidney function profiling using conventional and novel biomarkers in young adults: the African-PREDICT study. BMC Nephrology, 24, 96. (doi: 10.1186/s12882-023-03100-w) (PMID:37055746) (PMCID:PMC10103421)
Edgar, B. et al. (2023) The impact of renal artery stenting on therapeutic aims. Journal of Human Hypertension, 37(4), pp. 265-272. (doi: 10.1038/s41371-022-00785-8) (PMID:36526895) (PMCID:PMC10063438)
Rotbain Curovic, V. et al. (2023) Presence of retinopathy and incident kidney and cardiovascular events in type 2 diabetes with normoalbuminuria – a post-hoc analysis of the PRIORITY randomized clinical trial. Journal of Diabetes and its Complications, 37(4), 108433. (doi: 10.1016/j.jdiacomp.2023.108433) (PMID:36841085)
Kimera, I. D. et al. (2023) Integrated multi-month dispensing of antihypertensive and antiretroviral therapy to sustain hypertension and HIV control. Journal of Human Hypertension, 37(3), pp. 213-219. (doi: 10.1038/s41371-022-00655-3) (PMID:35246602) (PMCID:PMC8896410)
Picone, D. S., Peterson, G. M., Jackson, S. L., Campbell, N. R.C., Delles, C. , Olsen, M. H., Padwal, R., Schutte, A. E. and Sharman, J. E. (2023) Perceptions of pharmacists on the quality of automated blood pressure devices: a national survey. Journal of Human Hypertension, 37(3), pp. 235-240. (doi: 10.1038/s41371-022-00670-4) (PMID:35314763)
Chen, J. Y., Chew, K. S., Mary, S. , Boder, P., Bagordo, D., Rossi, G. P., Touyz, R. M. , Delles, C. and Rossitto, G. (2023) Skin-specific mechanisms of body fluid regulation in hypertension. Clinical Science, 137(3), pp. 239-250. (doi: 10.1042/CS20220609) (PMID:36648486)
de Beer, D., Mels, C. M. C., Schutte, A. E., Delles, C. , Mary, S. , Mullen, W. , Mischak, H. and Kruger, R. (2023) A urinary peptidomics approach for early stages of cardiovascular disease risk: the African-PREDICT study. Hypertension Research, 46(2), pp. 485-494. (doi: 10.1038/s41440-022-01097-7) (PMID:36396816)
Lim, M. W.S., Setjiadi, D., Dobbin, S. J.H., Lang, N. N. , Delles, C. and Connelly, P. J. (2023) Nailfold video-capillaroscopy in the study of cardiovascular disease: a systematic review. Blood Pressure Monitoring, 28(1), pp. 24-32. (doi: 10.1097/MBP.0000000000000624) (PMID:36281701) (PMCID:PMC9815820)
Rushworth, L. K. et al. (2023) Phase II proof of concept study of atorvastatin in castration resistant prostate cancer. BJU International, 131(2), pp. 236-243. (doi: 10.1111/bju.15851) (PMID:35844167) (PMCID:PMC10087532)
Sharman, J. E. et al. (2023) The urgency to regulate validation of automated blood pressure measuring devices: a policy statement and call to action from the world hypertension league. Journal of Human Hypertension, 37(2), pp. 155-159. (doi: 10.1038/s41371-022-00747-0) (PMID:36476777) (PMCID:PMC9957720)
Sattar, N. , Deanfield, J. and Delles, C. (2023) Impact of intentional weight loss in cardiometabolic disease: what we know about timing of benefits on differing outcomes? Cardiovascular Research, (doi: 10.1093/cvr/cvac186) (PMID:36683167) (Early Online Publication)
Sykes, R. et al. (2023) Adjudicated myocarditis and multisystem illness trajectory in healthcare workers post-COVID-19. Open Heart, 10(1), e002192. (doi: 10.1136/openhrt-2022-002192) (PMID:36822817) (PMCID:PMC9950584)
Kulkarni, S., Glover, M., Kapil, V., Abrams, S. M. L., Partridge, S., McCormack, T., Sever, P., Delles, C. and Wilkinson, I. B. (2023) Management of hypertensive crisis: British and Irish Hypertension Society position document. Journal of Human Hypertension, (doi: 10.1038/s41371-022-00776-9) (PMID:36418425) (Early Online Publication)
Murray, E. C. , Delles, C. , Orzechowski, P., Renc, P., Sitek, A., Wagenaar, J. and Guzik, T. J. (2022) Vascular phenotypes in early hypertension. Journal of Human Hypertension, (doi: 10.1038/s41371-022-00794-7) (Early Online Publication)
Rossitto, G. and Delles, C. (2022) Mechanisms of sodium-mediated injury in cardiovascular disease: old play, new scripts. FEBS Journal, 289(23), pp. 7260-7273. (doi: 10.1111/febs.16155) (PMID:34355504)
Mary, S. , Boder, P., Padmanabhan, S. , McBride, M. W. , Graham, D. , Delles, C. and Dominiczak, A. F. (2022) The role of uromodulin in salt-sensitive hypertension. Hypertension, 79, pp. 2419-2429. (doi: 10.1161/HYPERTENSIONAHA.122.19888) (PMID:36378920) (PMCID:PMC9553220)
Lip, S. , McCallum, L., Delles, C. , McClure, J. D. , Guzik, T., Berry, C. , Touyz, R. and Padmanabhan, S. (2022) Rationale and design for the LOnger-term effects of SARS-CoV-2 INfection on blood Vessels And blood pRessure (LOCHINVAR). Open Heart, 9(1), e002057. (doi: 10.1136/openhrt-2022-002057) (PMID:35750422) (PMCID:PMC9234432)
Connelly, P. J. , Currie, G. and Delles, C. (2022) Sex differences in the prevalence, outcomes and management of hypertension. Current Hypertension Reports, 24(6), pp. 185-192. (doi: 10.1007/s11906-022-01183-8) (PMID:35254589) (PMCID:PMC9239955)
Craig, A., Delles, C. and Murray, E. C. (2022) A review of vascular traits and assessment techniques, and their heritability. Artery Research, 28(2), pp. 61-78. (doi: 10.1007/s44200-022-00016-y)
Lucas-Herald, A. K. and Delles, C. (2022) Carotid intima-media thickness is associated with obesity and hypertension in young people. Hypertension, 79(6), pp. 1177-1179. (doi: 10.1161/hypertensionaha.122.19163) (PMID:35544586)
Rastogi, T. et al. (2022) Comparing and contrasting risk factors for heart failure in patients with and without history of myocardial infarction: data from HOMAGE and the UK Biobank. European Journal of Heart Failure, 24(6), pp. 976-984. (doi: 10.1002/ejhf.2495) (PMID:35365899) (PMCID:PMC9542039)
Wang, Y. et al. (2022) Associations of long-term visit-to-visit blood pressure variability with subclinical kidney damage and albuminuria in adulthood: a 30-year prospective cohort study. Hypertension, 79(6), pp. 1247-1256. (doi: 10.1161/HYPERTENSIONAHA.121.18658) (PMID:35360932) (PMCID:PMC9093226)
Lucas-Herald, A. K. et al. (2022) Vascular dysfunction and increased cardiovascular risk in hypospadias. European Heart Journal, 43(19), pp. 1832-1845. (doi: 10.1093/eurheartj/ehac112) (PMID:35567552) (PMCID:PMC9113289)
Rossitto, G. and Delles, C. (2022) Does excess tissue sodium storage regulate blood pressure? Current Hypertension Reports, 24(5), pp. 115-122. (doi: 10.1007/s11906-022-01180-x) (PMID:35192140) (PMCID:PMC9142429)
Maurovich-Horvat, P. et al. (2022) CT or invasive coronary angiography in stable chest pain. New England Journal of Medicine, 386(17), pp. 1591-1602. (doi: 10.1056/NEJMoa2200963) (PMID:35240010)
Toloza, F. J. K. et al. (2022) Association between maternal thyroid function and risk of gestational hypertension and pre-eclampsia: a systematic review and individual-participant data meta-analysis. Lancet Diabetes and Endocrinology, 10(4), pp. 243-252. (doi: 10.1016/S2213-8587(22)00007-9) (PMID:35255260)
Connelly, P. J. , Casey, H., Montezano, A. C., Touyz, R. M. and Delles, C. (2022) Sex steroids receptors, hypertension and vascular ageing. Journal of Human Hypertension, 36(2), pp. 120-125. (doi: 10.1038/s41371-021-00576-7) (PMID:34230581) (PMCID:PMC8850193)
Mujaj, B. et al. (2022) Aspirin use is associated with increased risk for incident heart failure: a patient-level pooled analysis. ESC Heart Failure, 9(1), pp. 685-694. (doi: 10.1002/ehf2.13688) (PMID:34808706) (PMCID:PMC8787993)
Delles, C. (2022) Maternally inherited essential hypertension: adding further complexity to an already complex condition. American Journal of Hypertension, 35(1), pp. 16-18. (doi: 10.1093/ajh/hpab133) (PMID:34427578) (PMCID:PMC8730502)
Delles, C. and Rossitto, G. (2022) Of snails, earthworms, and men: insights into strategies to preserve water. Function, 3(1), zqab071. (doi: 10.1093/function/zqab071) (PMID:35330922) (PMCID:PMC8788808)
Connelly, P. J. and Delles, C. (2021) Cardiovascular disease in transgender people: recent research and emerging evidence. Cardiovascular Research, 117(14), e174-e176. (doi: 10.1093/cvr/cvab288) (PMID:34568899) (PMCID:PMC8683701)
Mary, S. , Boder, P., Rossitto, G., Graham, L., Scott, K. , Flynn, A., Kipgen, D., Graham, D. and Delles, C. (2021) Salt loading decreases urinary excretion and increases intracellular accumulation of uromodulin in stroke-prone spontaneously hypertensive rats. Clinical Science, 135(24), pp. 2749-2761. (doi: 10.1042/CS20211017) (PMID:34870708) (PMCID:PMC8689196)
van Vliet, N. A. et al. (2021) Higher thyrotropin leads to unfavorable lipid profile and somewhat higher cardiovascular disease risk: evidence from multi-cohort Mendelian randomization and metabolomic profiling. BMC Medicine, 19, 266. (doi: 10.1186/s12916-021-02130-1) (PMID:34727949) (PMCID:PMC8565073)
He, T. et al. (2021) Urinary peptides in heart failure: a link to molecular pathophysiology. European Journal of Heart Failure, 23(11), pp. 1875-1887. (doi: 10.1002/ejhf.2195) (PMID:33881206)
Raafs, A. et al. (2021) Identification of sex‐specific biomarkers predicting new‐onset heart failure. ESC Heart Failure, 8(5), pp. 3512-3520. (doi: 10.1002/ehf2.13476) (PMID:34156155) (PMCID:PMC8497379)
Touyz, R. M. et al. (2021) Cardiovascular and renal risk factors and complications associated with COVID-19. CJC Open, 3(10), pp. 1257-1272. (doi: 10.1016/j.cjco.2021.05.020) (PMID:34151246) (PMCID:PMC8205551)
Docherty, N. G., Delles, C. , D’Haese, P., Layton, A. T., Martínez-Salgado, C., Vervaet, B. A. and López-Hernández, F. J. (2021) Haemodynamic frailty – A risk factor for acute kidney injury in the elderly. Ageing Research Reviews, 70, 101408. (doi: 10.1016/j.arr.2021.101408) (PMID:34271185)
Boder, P., Mary, S. , Mark, P. B. , Leiper, J. , Dominiczak, A. F. , Padmanabhan, S. , Rampold, L. and Delles, C. (2021) Mechanistic interactions of uromodulin with the thick ascending limb: perspectives in physiology and hypertension. Journal of Hypertension, 39(8), pp. 1490-1504. (doi: 10.1097/HJH.0000000000002861) (PMID:34187999) (PMCID:PMC7611110)
Mary, S. , Small, H., Herse, F., Carrick, E., Flynn, A., Mullen, W. , Dechend, R. and Delles, C. (2021) Pre-existing hypertension and pregnancy induced hypertension reveal molecular differences in placental proteome in rodents. Physiological Genomics, 53(6), pp. 259-268. (doi: 10.1152/physiolgenomics.00160.2020) (PMID:33969702)
Murray, E. , Rossitto, G. and Delles, C. (2021) Haemodynamic assessment in hypertension: the soloists and the orchestra. Journal of Hypertension, 39(6), pp. 1109-1111. (doi: 10.1097/HJH.0000000000002796) (PMID:33967215)
Rossitto, G. et al. (2021) High sodium intake, glomerular hyperfiltration and protein catabolism in patients with essential hypertension. Cardiovascular Research, 117(5), pp. 1372-1381. (doi: 10.1093/cvr/cvaa205) (PMID:33053160) (PMCID:PMC8064429)
Connelly, P. J. , Azizi, Z., Alipour, P., Delles, C. , Pilote, L. and Raparelli, V. (2021) The importance of gender to understand sex differences in cardiovascular disease. Canadian Journal of Cardiology, 37(5), pp. 699-710. (doi: 10.1016/j.cjca.2021.02.005) (PMID:33592281)
Scott, K. , Morgan, H. L., Delles, C. , Fisher, S., Graham, D. and McBride, M. W. (2021) Distinct uterine artery gene expression profiles during early gestation in the stroke-prone spontaneously hypertensive rat. Physiological Genomics, 53(4), pp. 160-171. (doi: 10.1152/physiolgenomics.00159.2020) (PMID:33719581)
Vlahou, A. et al. (2021) Data sharing under the General Data Protection Regulation: time to harmonize law and research ethics? Hypertension, 77(4), pp. 1029-1035. (doi: 10.1161/HYPERTENSIONAHA.120.16340) (PMID:33583200) (PMCID:PMC7968961)
Crouch, S. H., Botha-Le Roux, S., Delles, C. , Graham, L. A. and Schutte, A. E. (2021) Inflammation and salt in young adults: the African-PREDICT study. European Journal of Nutrition, 60(2), pp. 873-882. (doi: 10.1007/s00394-020-02292-3) (PMID:32494865) (PMCID:PMC7900065)
Neves, K. B. , Morris, H., Alves-Lopes, R., Muir, K. W. , Moreton, F., Delles, C. , Montezano, A. C. and Touyz, R. M. (2021) Peripheral arteriopathy caused by Notch3 gain-of-function mutation involves ER and oxidative stress and blunting of NO∕sGC∕cGMP pathway. Clinical Science, 135(6), pp. 753-773. (doi: 10.1042/CS20201412) (PMID:33681964)
Connelly, P. J. , Clark, A., Touyz, R. M. and Delles, C. (2021) Transgender adults, gender-affirming hormone therapy and blood pressure: a systematic review. Journal of Hypertension, 39(2), pp. 223-230. (doi: 10.1097/HJH.0000000000002632) (PMID:32809982) (PMCID:PMC7810409)
Moreton, F. C., Cullen, B. , Dickie, D. A. , Lopez Gonzalez, R., Santosh, C., Delles, C. and Muir, K. W. (2021) Brain imaging factors associated with progression of subcortical hyperintensities in CADASIL over two year follow up. European Journal of Neurology, 28(1), pp. 220-228. (doi: 10.1111/ene.14534) (PMID:32931073)
Small, H. Y. and Delles, C. (2021) Letter to the Editor regarding Cunningham et al. 2020. Hypertension in Pregnancy, 40(2), p. 133. (doi: 10.1080/10641955.2021.1899201) (PMID:33834935)
Rossitto, G. et al. (2020) Reduced lymphatic reserve in heart failure with preserved ejection fraction. Journal of the American College of Cardiology, 76(24), pp. 2817-2829. (doi: 10.1016/j.jacc.2020.10.022) (PMID:33303070) (PMCID:PMC7724570)
Mangion, K. et al. (2020) The Chief Scientist Office cardiovascular and pulmonary imaging in SARS Coronavirus disease-19 (CISCO-19) study. Cardiovascular Research, 116(14), pp. 2185-2196. (doi: 10.1093/cvr/cvaa209) (PMID:32702087) (PMCID:PMC7454350)
Rossitto, G. et al. (2020) Tissue sodium excess is not hypertonic and reflects extracellular volume expansion. Nature Communications, 11, 4222. (doi: 10.1038/s41467-020-17820-2) (PMID:32839436) (PMCID:PMC7445299)
Campbell, R. T. et al. (2020) The novel urinary proteomic classifier HF1 has similar diagnostic and prognostic utility to BNP in heart failure. ESC Heart Failure, 7(4), pp. 1595-1604. (doi: 10.1002/ehf2.12708) (PMID:32383555) (PMCID:PMC7373887)
Connelly, P. J. , Jandeleit-Dahm, K. A.M. and Delles, C. (2020) Sex and gender aspects in vascular pathophysiology. Clinical Science, 134(16), pp. 2203-2207. (doi: 10.1042/CS20200876) (PMID:32844996)
Demin, A., Løge, B., Zhiteneva, O., Nishida, C., Whiting, S., Rippin, H., Delles, C. , Karymbaeva, S., Wickramasinghe, K. and Breda, J. (2020) Trans fatty acid elimination policy in member states of the Eurasian Economic Union: implementation challenges and capacity for enforcement. Journal of Clinical Hypertension, 22(8), pp. 1328-1337. (doi: 10.1111/jch.13945) (PMID:32677762)
Dobbie, L. J., Mackin, S. T., Hogarth, K., Lonergan, F., Kannenkeril, D., Brooksbank, K. and Delles, C. (2020) Validation of semi-automated flow mediated dilation measurement in healthy volunteers. Blood Pressure Monitoring, 25(4), pp. 216-223. (doi: 10.1097/MBP.0000000000000448) (PMID:32304385) (PMCID:PMC7331823)
Tarar, O. M., Ahmed, K. M., Nishtar, N. A., Achakzai, A. B. K., Gulzar, Y., Delles, C. and Al-Jawaldeh, A. (2020) Understanding the complexities of prevalence of trans fat and its control in food supply in Pakistan. Journal of Clinical Hypertension, 22(8), pp. 1338-1346. (doi: 10.1111/jch.13943) (PMID:32687252)
Currie, G. , Mary, S. and Delles, C. (2020) Is there a role for proteomics in diabetic renal disease? NDT Plus, 35(7), pp. 1133-1135. (doi: 10.1093/ndt/gfz017) (PMID:32777079) (PMCID:PMC7417003)
Derakhshan, A. et al. (2020) Association of maternal thyroid function with birth weight: a systematic review and individual-participant data meta-analysis. Lancet Diabetes and Endocrinology, 8(6), pp. 501-510. (doi: 10.1016/S2213-8587(20)30061-9) (PMID:32445737)
Picone, D. S. et al. (2020) Nonvalidated home blood pressure devices dominate the online marketplace in Australia: major implications for cardiovascular risk management. Hypertension, 75(6), pp. 1593-1599. (doi: 10.1161/hypertensionaha.120.14719) (PMID:32275193)
Delles, C. and Olfert, M. (2020) Electronic cigarettes: how bad are they for your health? Cardiovascular Research, 116(6), e64-e66. (doi: 10.1093/cvr/cvaa041) (PMID:32157289)
Delles, C. , Li, H. and Touyz, R. M. (2020) ACE2 the Janus-faced protein – from cardiovascular protection to severe acute respiratory syndrome-coronavirus and COVID-19. Clinical Science, 134(7), pp. 747-750. (doi: 10.1042/CS20200363)
Tofte, N. et al. (2020) Early detection of diabetic kidney disease by urinary proteomics and subsequent intervention with spironolactone to delay progression (PRIORITY): a prospective observational study and embedded randomised placebo-controlled trial. Lancet Diabetes and Endocrinology, 8(4), pp. 301-312. (doi: 10.1016/S2213-8587(20)30026-7) (PMID:32135136)
Crouch, S. H., Botha-Le Roux, S., Delles, C. , Graham, L. A. and Schutte, A. E. (2020) Distinct inflammatory mediator patterns in young black and white adults: The African-PREDICT study. Cytokine, 126, 154894. (doi: 10.1016/j.cyto.2019.154894)
Schlosser, K., Kaur, A., Dayan, N., Stewart, D. J., Pilote, L. and Delles, C. (2020) Circulating miR-206 and Wnt-signaling are associated with cardiovascular complications and a history of preeclampsia in women. Clinical Science, 134(2), pp. 87-101. (doi: 10.1042/CS20190920) (PMID:31899480)
Neves, K. B. et al. (2019) ER stress and Rho kinase activation underlie the vasculopathy of CADASIL. JCI Insight, 4(23), e131344. (doi: 10.1172/jci.insight.131344) (PMID:31647781) (PMCID:PMC6962020)
Cameron, A. C. et al. (2019) Progressive hypertension and severe left ventricular outflow tract obstruction. Hypertension, 74(6), pp. 1216-1225. (doi: 10.1161/hypertensionaha.119.13343) (PMID:31587571)
Connelly, P. J. , Freel, E. M., Perry, C., Ewan, J., Touyz, R. M. , Currie, G. and Delles, C. (2019) Gender-affirming hormone therapy, vascular health and cardiovascular disease in transgender adults. Hypertension, 74(6), pp. 1266-1274. (doi: 10.1161/HYPERTENSIONAHA.119.13080) (PMID:31656099) (PMCID:PMC6887638)
Iliodromiti, S., Sattar, N. , Delles, C. , Nelson, S. M. , Gill, J. M.R. and Lumsden, M. (2019) Menopausal hot flashing and endothelial function in two vascular beds: findings from a cross-sectional study of postmenopausal women. Menopause, 26(9), pp. 1002-1009. (doi: 10.1097/GME.0000000000001386) (PMID:31453962)
Korevaar, T. I. M. et al. (2019) Association of thyroid function test abnormalities and thyroid autoimmunity with preterm birth: a systematic review and meta-analysis. JAMA: Journal of the American Medical Association, 322(7), pp. 632-641. (doi: 10.1001/jama.2019.10931) (PMID:31429897) (PMCID:PMC6704759)
Welsh, C. et al. (2019) Urinary sodium excretion, blood pressure and risk of future cardiovascular disease and mortality in subjects without prior cardiovascular disease. Hypertension, 73, pp. 1202-1209. (doi: 10.1161/HYPERTENSIONAHA.119.12726) (PMID:31067194)
Schanstra, J. P. et al. (2019) Systems biology identifies cytosolic PLA2 as a target in vascular calcification treatment. JCI Insight, 4(10), e125638. (doi: 10.1172/jci.insight.125638)
Small, H. Y., McNeilly, S., Mary, S. , Sheikh, A. M. and Delles, C. (2019) Resistin mediates sex-dependent effects of perivascular adipose tissue on vascular function in the SHRSP. Scientific Reports, 9, 6897. (doi: 10.1038/s41598-019-43326-z) (PMID:31053755) (PMCID:PMC6499830)
Currie, G. and Delles, C. (2019) Vascular biomedicine in an era of chronic disease and multimorbidity. Clinical Science, 133(9), pp. 1137-1143. (doi: 10.1042/CS20180764) (PMID:31088896) (PMCID:PMC6522703)
Ferreira, J. P. et al. (2019) Proteomic bioprofiles and mechanistic pathways of progression to heart failure: the HOMAGE study. Circulation, 12(5), e005897. (doi: 10.1161/CIRCHEARTFAILURE.118.005897) (PMID:31104495)
Lucas-Herald, A. K. , Zürbig, P., Mason, A., Kinning, E., Brown, C. E., Mansoorian, B., Mullen, W. , Ahmed, S. F. and Delles, C. (2019) Proteomic evidence of biological aging in a child with a compound heterozygous ZMPSTE24 mutation. Proteomics Clinical Applications, 13(2), 1800135. (doi: 10.1002/prca.201800135) (PMID:30548811) (PMCID:PMC6492098)
Kerr, D. M.I., Brooksbank, K. J.M., Taylor, R. G., Pinel, K., Rios, F. J. , Touyz, R. M. and Delles, C. (2019) Acute effects of electronic and tobacco cigarettes on vascular and respiratory function in healthy volunteers: a cross-over study. Journal of Hypertension, 37(1), pp. 154-166. (doi: 10.1097/HJH.0000000000001890) (PMID:30063637)
Rossitto, G., Touyz, R. M. , Petrie, M. C. and Delles, C. (2018) Much Ado about N...atrium: modelling tissuesodium as a highly sensitive marker of subclinicaland localized oedema. Clinical Science, 132(24), pp. 2609-2613. (doi: 10.1042/CS20180575) (PMID:30545897) (PMCID:PMC6365627)
Sliz, E. et al. (2018) Metabolomic consequences of genetic inhibition of PCSK9 compared with statin treatment. Circulation, 138(22), pp. 2499-2512. (doi: 10.1161/CIRCULATIONAHA.118.034942) (PMID:30524137)
Dayan, N., Schlosser, K., Stewart, D. J., Delles, C. , Kaur, A. and Pilote, L. (2018) Circulating microRNAs implicate multiple atherogenic abnormalities in the long-term cardiovascular sequelae of preeclampsia. American Journal of Hypertension, 31(10), pp. 1093-1097. (doi: 10.1093/ajh/hpy069) (PMID:29800045) (PMCID:PMC6132124)
Tofte, N. et al. (2018) Characteristics of high- and low-risk individuals in the PRIORITY study: urinary proteomics and mineralocorticoid receptor antagonism for prevention of diabetic nephropathy in Type 2 diabetes. Diabetic Medicine, 35(10), pp. 1375-1382. (doi: 10.1111/dme.13669) (PMID:29781558)
Ravassa, S. et al. (2018) Biomarker-based phenotyping of myocardial fibrosis identifies patients with heart failure with preserved ejection fraction resistant to the beneficial effects of spironolactone: results from the Aldo-DHF trial. European Journal of Heart Failure, 20(9), pp. 1290-1299. (doi: 10.1002/ejhf.1194) (PMID:29709099)
Gillis, K. , Stevens, K. K., Bell, E., Patel, R. K., Jardine, A. G. , Morris, S. T.W., Schneider, M. P., Delles, C. and Mark, P. B. (2018) Ascorbic acid lowers central blood pressure and asymmetric dimethylarginine in chronic kidney disease. Clinical Kidney Journal, 11(4), pp. 532-539. (doi: 10.1093/ckj/sfx158) (PMID:30094018) (PMCID:PMC6070083)
Moreton, F. C., Cullen, B. , Delles, C. , Santosh, C., Lopez Gonzalez, R., Dani, K. and Muir, K. W. (2018) Vasoreactivity in CADASIL: comparison to structural MRI and neuropsychology. Journal of Cerebral Blood Flow and Metabolism, 38(6), pp. 1085-1095. (doi: 10.1177/0271678X17710375) (PMID:28537106)
Lygirou, V., Latosinska, A., Makridakis, M., Mullen, W. , Delles, C. , Schanstra, J. P., Zoidakis, J., Pieske, B., Mischak, H. and Vlahou, A. (2018) Plasma proteomic analysis reveals altered protein abundances in cardiovascular disease. Journal of Translational Medicine, 16(1), 104. (doi: 10.1186/s12967-018-1476-9) (PMID:29665821) (PMCID:PMC5905170)
Currie, G. E. et al. (2018) Urinary proteomics for prediction of mortality in patients with type 2 diabetes and microalbuminuria. Cardiovascular Diabetology, 17, 50. (doi: 10.1186/s12933-018-0697-9) (PMID:29625564) (PMCID:PMC5889591)
Delles, C. and Currie, G. (2018) Sex differences in hypertension and other cardiovascular diseases. Journal of Hypertension, 36(4), pp. 768-770. (doi: 10.1097/HJH.0000000000001655) (PMID:29489615) (PMCID:PMCID: PMC5856361)
Delles, C. et al. (2018) Nuclear magnetic resonance-based metabolomics identifies phenylalanine as a novel predictor of incident heart failure hospitalisation: results from PROSPER and FINRISK 1997. European Journal of Heart Failure, 20, pp. 663-673. (doi: 10.1002/ejhf.1076) (PMID:29226610) (PMCID:PMC5947152)
Feng, Y.-M. et al. (2018) Glomerular function in relation to circulating adhesion molecules and inflammation markers in a general population. Nephrology Dialysis Transplantation, 33(3), pp. 426-435. (doi: 10.1093/ndt/gfx256) (PMID:28992257)
Currie, G. and Delles, C. (2018) Blood pressure targets in the elderly. Journal of Hypertension, 36(2), pp. 234-236. (doi: 10.1097/HJH.0000000000001576)
Delles, C. , Carrick, E., Graham, D. and Nicklin, S. A. (2018) Utilising proteomics to understand and define hypertension: where are we and where do we go? Expert Review of Proteomics, 15(7), pp. 581-592. (doi: 10.1080/14789450.2018.1493927) (PMID:29999442) (PMCID:PMC6092739)
Krochmal, M. et al. (2017) Urinary peptidomics analysis reveals proteases involved in diabetic nephropathy. Scientific Reports, 7, 15160. (doi: 10.1038/s41598-017-15359-9) (PMID:29123184) (PMCID:PMC5680307)
Pontillo, C. et al. (2017) Prediction of chronic kidney disease stage 3 by CKD273, a urinary proteomic biomarker. Kidney International Reports, 2(6), pp. 1066-1075. (doi: 10.1016/j.ekir.2017.06.004) (PMID:29130072) (PMCID:PMC5669285)
Schmieder, R. E. et al. (2017) The effect of sacubitril/valsartan compared to olmesartan on cardiovascular remodelling in subjects with essential hypertension: the results of a randomized, double-blind, active-controlled study. European Heart Journal, 38(44), pp. 3308-3317. (doi: 10.1093/eurheartj/ehx525) (PMID:29029087)
Stevens, K., Denby, L., Patel, R. K., Mark, P. B. , Kettlewell, S., Smith, G. L. , Clancy, M. J., Delles, C. and Jardine, A. G. (2017) Deleterious effects of phosphate on vascular and endothelial function via disruption to the nitric oxide pathway. Nephrology Dialysis Transplantation, 32(10), pp. 1617-1627. (doi: 10.1093/ndt/gfw252) (PMID:27448672) (PMCID:PMC5837731)
Krochmal, M. et al. (2017) Identification of novel molecular signatures of IgA nephropathy through an integrative -omics analysis. Scientific Reports, 7, 9091. (doi: 10.1038/s41598-017-09393-w) (PMID:28831120) (PMCID:PMC5567309)
Currie, G. and Delles, C. (2017) Healthy vascular ageing. Hypertension, 70(2), pp. 229-231. (doi: 10.1161/HYPERTENSIONAHA.117.09122) (PMID:28559393)
Gajjala, P. R. et al. (2017) Proteomic-biostatistic integrated approach for finding the underlying molecular determinants of hypertension in human plasma. Hypertension, 70, pp. 412-419. (doi: 10.1161/HYPERTENSIONAHA.116.08906) (PMID:28652472)
Small, H. Y., Cornelius, D. C., Guzik, T. J. and Delles, C. (2017) Natural killer cells in placentation and cancer: Implications for hypertension during pregnancy. Placenta, 56, pp. 59-64. (doi: 10.1016/j.placenta.2017.03.003) (PMID:28318556)
Zhang, Z.‐Y. et al. (2017) Novel urinary peptidomic classifier predicts incident heart failure. Journal of the American Heart Association, 6(8), e005432. (doi: 10.1161/JAHA.116.005432) (PMID:28784649) (PMCID:PMC5586413)
Knez, J. et al. (2017) Peripheral blood mitochondrial DNA content in relation to circulating metabolites and inflammatory markers: a population study. PLoS ONE, 12(7), e0181036. (doi: 10.1371/journal.pone.0181036) (PMID:28704533) (PMCID:PMC5509283)
Neisius, U., Olson, E., Rossi, S. H., Ibrahim, H. A., Currie, G. , Dominiczak, A. and Delles, C. (2017) Evaluation of the systemic micro- and macrovasculature in stable angina: a case-control study. PLoS ONE, 12(5), e0178412. (doi: 10.1371/journal.pone.0178412) (PMID:28542516) (PMCID:PMC5444845)
Jacobs, L. et al. (2017) Risk for incident heart failure: a subject-level meta-analysis from the Heart “OMics” in AGEing (HOMAGE) study. Journal of the American Heart Association, 6(5), e005231. (doi: 10.1161/JAHA.116.005231) (PMID:28465299)
Mary, S. , Small, H. Y., Siwy, J., Mullen, W. , Giri, A. and Delles, C. (2017) Polymerization-incompetent uromodulin in the pregnant stroke-prone spontaneously hypertensive rat. Hypertension, 69(5), pp. 910-918. (doi: 10.1161/HYPERTENSIONAHA.116.08826) (PMID:28348009) (PMCID:PMC5389592)
Dominiczak, A. , Delles, C. and Padmanabhan, S. (2017) Genomics and precision medicine for clinicians and scientists in hypertension. Hypertension, 69(4), e10-e13. (doi: 10.1161/HYPERTENSIONAHA.116.08252) (PMID:28193712)
Htun, N. M. et al. (2017) Prediction of acute coronary syndromes by urinary proteome analysis. PLoS ONE, 12(3), e0172036.. (doi: 10.1371/journal.pone.0172036) (PMID:28273075) (PMCID:PMC5342174)
Carty, D. M., Doogan, F., Welsh, P. , Dominiczak, A. F. and Delles, C. (2017) Thyroid stimulating hormone (TSH) ≥2.5mU/l in early pregnancy: prevalence and subsequent outcomes. European Journal of Obstetrics and Gynecology and Reproductive Biology, 210, pp. 366-369. (doi: 10.1016/j.ejogrb.2017.01.048) (PMID:28153744)
Currie, G. and Delles, C. (2017) The future of "omics" in hypertension. Canadian Journal of Cardiology, 33(5), pp. 601-610. (doi: 10.1016/j.cjca.2016.11.023) (PMID:28161100) (PMCID:5417769)
Small, H. Y., Akehurst, C., Sharafetdinova, L., McBride, M. W. , McClure, J. D. , Robinson, S. W., Carty, D. M., Freeman, D. J. and Delles, C. (2017) HLA gene expression is altered in whole blood and placenta from women who later developed preeclampsia. Physiological Genomics, 49(3), pp. 193-200. (doi: 10.1152/physiolgenomics.00106.2016) (PMID:28130428) (PMCID:PMC5374453)
Delles, C. and Vanholder, R. (2017) Chronic kidney disease. Clinical Science, 131(3), pp. 225-226. (doi: 10.1042/CS20160624) (PMID:28057893)
Ferreira, J. P. et al. (2016) Renal function estimation and Cockroft–Gault formulas for predicting cardiovascular mortality in population-based, cardiovascular risk, heart failure and post-myocardial infarction cohorts: the Heart ‘OMics’ in AGEing (HOMAGE) and the high-risk myocardial infarction database initiatives. BMC Medicine, 14, 181. (doi: 10.1186/s12916-016-0731-2) (PMID:27829460) (PMCID:PMC5103492)
Rutherford, C. et al. (2016) Phosphorylation of Janus kinase 1 (JAK1) by AMP-activated protein kinase (AMPK) links energy sensing to anti-inflammatory signaling. Science Signaling, 9(453), ra109. (doi: 10.1126/scisignal.aaf8566) (PMID:27919027)
Currie, G. and Delles, C. (2016) Urinary proteomics for diagnosis and monitoring of diabetic nephropathy. Current Diabetes Reports, 16(11), 104. (doi: 10.1007/s11892-016-0798-3) (PMID:27658932)
Small, H. Y., Nosalski, R., Morgan, H., Beattie, E., Guzik, T., Graham, D. and Delles, C. (2016) The role of tumor necrosis factor-α and natural killer cells in uterine artery function and pregnancy outcome in the stroke prone spontaneously hypertensive rat. Hypertension, 68(5), pp. 1298-1307. (doi: 10.1161/HYPERTENSIONAHA.116.07933) (PMID:27733586) (PMCID:PMC5058643)
Currie, G. et al. (2016) Effect of mineralocorticoid receptor antagonists on proteinuria and progression of chronic kidney disease: a systematic review and meta-analysis. BMC Nephrology, 17, 127. (doi: 10.1186/s12882-016-0337-0) (PMID:27609359) (PMCID:PMC5015203)
Mordi, I., Mordi, N., Delles, C. and Tzemos, N. (2016) Endothelial dysfunction in human essential hypertension. Journal of Hypertension, 34(8), pp. 1464-1472. (doi: 10.1097/hjh.0000000000000965) (PMID:27203578)
Currie, G. and Delles, C. (2016) Use of biomarkers in the evaluation and treatment of hypertensive patients. Current Hypertension Reports, 18(7), 54. (doi: 10.1007/s11906-016-0661-6) (PMID:27221728)
Wan Sulaiman, W.N., Caslake, M.J., Delles, C. , Karlsson, H., Mulder, M.T., Graham, D. and Freeman, D.J. (2016) Does high-density lipoprotein protect vascular function in healthy pregnancy? Clinical Science, 130(7), pp. 491-497. (doi: 10.1042/cs20150475) (PMID:26888561)
Eisele, N. et al. (2016) Placental expression of the angiogenic placental growth factor is stimulated by both aldosterone and simulated starvation. Placenta, 40, pp. 18-24. (doi: 10.1016/j.placenta.2016.02.004) (PMID:27016778)
Neisius, U. et al. (2016) Urine proteomics in the diagnosis of stable angina. BMC Cardiovascular Disorders, 16, 70. (doi: 10.1186/s12872-016-0246-y) (PMID:27095611) (PMCID:PMC483761)
Mullan, A., Delles, C. , Ferrell, W., Mullen, W. , Edwards, C. A. , McColl, J. H. , Roberts, S. A. and Lean, M. (2016) Effects of a beverage rich in (poly)phenols on established and novel risk markers for vascular disease in medically uncomplicated overweight or obese subjects: A four week randomized trial. Atherosclerosis, 246, pp. 169-176. (doi: 10.1016/j.atherosclerosis.2016.01.004) (PMID:26797134)
Currie, G. , Delles, C. , Touyz, R. M. , Staessen, J. A., Dominiczak, A. F. , Jennings, G. L. R. and Wang, J.-G. (2016) A woman with treatment-resistant hypertension. Hypertension, 67(2), pp. 243-250. (doi: 10.1161/HYPERTENSIONAHA.115.06756) (PMID:26711735)
Small, H. Y., Currie, G. E. and Delles, C. (2016) Prostasin, proteases, and preeclampsia. Journal of Hypertension, 34(2), pp. 193-195. (doi: 10.1097/hjh.0000000000000828) (PMID:26682786)
Small, H. Y., Morgan, H., Beattie, E., Griffin, S., Indahl, M., Delles, C. and Graham, D. (2016) Abnormal uterine artery remodelling in the stroke prone spontaneously hypertensive rat. Placenta, 37, pp. 34-44. (doi: 10.1016/j.placenta.2015.10.022) (PMID:26612342) (PMCID:PMC4721537)
Gillis, K. A. , Mccomb, C., Patel, R. K., Stevens, K. K., Schneider, M. P., Radjenovic, A. , Morris, S. T.W., Roditi, G. H., Delles, C. and Mark, P. B. (2016) Non-contrast renal magnetic resonance imaging to assess perfusion and corticomedullary differentiation in health and chronic kidney disease. Nephron, 133(3), pp. 183-192. (doi: 10.1159/000447601) (PMID:27362585)
Lindhardt, M. et al. (2016) Proteomic prediction and Renin angiotensin aldosterone system Inhibition prevention Of early diabetic nephRopathy in TYpe 2 diabetic patients with normoalbuminuria (PRIORITY): essential study design and rationale of a randomised clinical multicentre trial. BMJ Open, 6(3), e010310. (doi: 10.1136/bmjopen-2015-010310) (PMID:26936907) (PMCID:PMC4785328)
McCallum, J. E., Mackenzie, A. E., Divorty, N., Clarke, C., Delles, C. , Milligan, G. and Nicklin, S. A. (2016) G protein-coupled receptor 35 mediates human saphenous vein vascular smooth muscle cell migration and endothelial cell proliferation. Journal of Vascular Research, 52(6), pp. 383-395. (doi: 10.1159/000444754) (PMID:27064272) (PMCID:PMC4959467)
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Sheikh, A. M., Small, H. Y., Currie, G. and Delles, C. (2016) Systematic review of micro-RNA expression in pre-eclampsia identifies a number of common pathways associated with the disease. PLoS ONE, 11(8), e0160808. (doi: 10.1371/journal.pone.0160808) (PMID:27529341) (PMCID:PMC4986940)
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Lindsey, M. L. et al. (2015) Transformative impact of proteomics on cardiovascular health and disease: a scientific statement from the American Heart Association. Circulation, 132(9), pp. 852-872. (doi: 10.1161/CIR.0000000000000226) (PMID:26195497)
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Dakin, R. S., Parker, A. L., Delles, C. , Nicklin, S. A. and Baker, A. H. (2015) Efficient transduction of primary vascular cells by the rare adenovirus serotype 49 vector. Human Gene Therapy, 26(5), pp. 312-319. (doi: 10.1089/hum.2015.019) (PMID:25760682) (PMCID:PMC4442572)
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Ravassa, S., Kuznetsova, T., Varo, N., Thijs, L., Delles, C. , Dominiczak, A. , Díez, J. and Staessen, J. A. (2015) Biomarkers of cardiomyocyte injury and stress identify left atrial and left ventricular remodelling and dysfunction: a population-based study. International Journal of Cardiology, 185, pp. 177-185. (doi: 10.1016/j.ijcard.2015.03.046) (PMID:25796005)
McInnes, I. B. et al. (2015) Effect of interleukin-6 receptor blockade on surrogates of vascular risk in rheumatoid arthritis: MEASURE, a randomised, placebo-controlled study. Annals of the Rheumatic Diseases, 74(4), pp. 694-702. (doi: 10.1136/annrheumdis-2013-204345) (PMID:24368514) (PMCID:PMC4392313)
Mischak, H., Delles, C. , Vlahou, A. and Vanholder, R. (2015) Proteomic biomarkers in kidney disease: issues in development and implementation. Nature Reviews Nephrology, 11(4), pp. 221-232. (doi: 10.1038/nrneph.2014.247) (PMID:25643662)
Brown, C. E. et al. (2015) Urinary proteomic biomarkers to predict cardiovascular events. Proteomics Clinical Applications, 9(5-6), pp. 610-617. (doi: 10.1002/prca.201400195) (PMID:25786980)
Mistry, H.D., Eisele, N., Escher, G., Dick, B., Surbek, D., Delles, C. , Currie, G. , Schlembach, D., Mohaupt, M.G. and Gennari-Moser, C. (2015) Gestation-specific reference intervals for comprehensive spot urinary steroid hormone metabolite analysis in normal singleton pregnancy and 6 weeks postpartum. Reproductive Biology and Endocrinology, 13, 101. (doi: 10.1186/s12958-015-0100-6) (PMID:26337185) (PMCID:PMC4559160)
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Currie, G. , McKay, G. and Delles, C. (2014) Biomarkers in diabetic nephropathy: present and future. World Journal of Diabetes, 5(6), pp. 763-776. 25512779. (doi: 10.4239/wjd.v5.i6.763) (PMID:PMC4265863)
Herbert, A. et al. (2014) Establishing reference values for central blood pressure and its amplification in a general healthy population and according to cardiovascular risk factors. European Heart Journal, 35(44), pp. 3122-3133. (doi: 10.1093/eurheartj/ehu293) (PMID:25112663)
Brown, C.E., O'Sullivan, D., Tennant, S., Dean, J., Murday, V., Oxnard, D., Hailey, H., Rankin, A.C., Tobias, E.S. and Delles, C. (2014) Cascade testing for long QT syndrome in Scotland. Scottish Medical Journal, 59(3), e27. (doi: 10.1177/0036933014540096)
Siwy, J. et al. (2014) Multicentre prospective validation of a urinary peptidome-based classifier for the diagnosis of type 2 diabetic nephropathy. Nephrology Dialysis Transplantation, 29(8), pp. 1563-1570. (doi: 10.1093/ndt/gfu039)
Persu, A. et al. (2014) Eligibility for renal denervation: experience at 11 European expert centers. Hypertension, 63(6), pp. 1319-25. (doi: 10.1161/HYPERTENSIONAHA.114.03194) (PMID:24664290)
Husi, H., Van Agtmael, T. , Mullen, W. , Bahlmann, F. H., Schanstra, J. P., Vlahou, A., Delles, C. , Perco, P. and Mischak, H. (2014) Proteome-based systems biology analysis of the diabetic mouse aorta reveals major changes in fatty acid biosynthesis as potential hallmark in diabetes mellitus-associated vascular disease. Circulation: Cardiovascular Genetics, 7(2), pp. 161-170. (doi: 10.1161/CIRCGENETICS.113.000196)
Tragante, V. et al. (2014) Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple blood-pressure-related loci. American Journal of Human Genetics, 94(3), pp. 349-360. (doi: 10.1016/j.ajhg.2013.12.016) (PMID:24560520) (PMCID:PMC3951943)
Mark, P.B. , Boyle, S., Zimmerli, L.U., McQuarrie, E.P., Delles, C. and Freel, E.M. (2014) Alterations in vascular function in primary aldosteronism - a cardiovascular magnetic resonance imaging study. Journal of Human Hypertension, 28(2), pp. 92-97. (doi: 10.1038/jhh.2013.70)
Carty, D.M., Neisius, U., Rooney, L.K., Dominiczak, A.F. and Delles, C. (2014) Pulse wave analysis for the prediction of preeclampsia. Journal of Human Hypertension, 28(2), pp. 98-104. (doi: 10.1038/jhh.2013.64)
Klein, J., Buffin-Meyer, B., Mullen, W. , Carty, D. M., Delles, C. , Vlahou, A., Mischak, H., Decramer, S., Bascands, J.-L. and Schanstra, J. P. (2014) Clinical proteomics in obstetrics and neonatology. Expert Review of Proteomics, 11(1), pp. 75-89. (doi: 10.1586/14789450.2014.872564)
Denby, L. et al. (2014) MicroRNA-214 antagonism protects against renal fibrosis. Journal of the American Society of Nephrology, 25(1), pp. 65-80. (doi: 10.1681/ASN.2013010072) (PMID:24158985) (PMCID:PMC3871772)
Gillis, K.A. et al. (2014) Inter-study reproducibility of arterial spin labelling magnetic resonance imaging for measurement of renal perfusion in healthy volunteers at 3 Tesla. BMC Nephrology, 15(23), (doi: 10.1186/1471-2369-15-23)
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Jacobs, L. et al. (2014) Heart 'omics' in AGEing (HOMAGE): design, research objectives and characteristics of the common database. Journal of Biomedical Research, 28(5), pp. 349-359. (doi: 10.7555/JBR.28.20140045) (PMID:25332706) (PMCID:PMC4197385)
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Brown, C.E. et al. (2013) Predictors of QTc and QTc prolongation in the generation scotland family study. Journal of Human Hypertension, 27(10), p. 639. (doi: 10.1038/jhh.2013.72)
Rossi, S. H. et al. (2013) Impaired renal function impacts negatively on vascular stiffness in patients with coronary artery disease. BMC Nephrology, 14(173), (doi: 10.1186/1471-2369-14-173)
Brown, C., Murday, V., Oxnard, D., Anusas, J., Tobias, E.S. , Delles, C. and Findlay, I. (2013) Sudden death referrals to the West of Scotland Inherited Cardiac Conditions Clinic: an overview of findings in probands with a structurally normal heart. Scottish Medical Journal, 58(3), e40-e41. (doi: 10.1177/0036933013495794)
Carty, D.M., Dominiczak, A. and Delles, C. (2013) Pulse wave analysis for prediction of preeclampsia. Endocrine Reviews, 34(3), SAT-520.
Delles, C. (2013) Homocysteine and the very elderly. Journal of Hypertension, 31(5), pp. 874-876. (doi: 10.1097/HJH.0b013e328360aa8b)
Delles, C. and Freel, E.M. (2013) Aldosterone, vascular endothelial growth factor, and preeclampsia: a mystery solved? Hypertension, 61(5), pp. 958-960. (doi: 10.1161/HYPERTENSIONAHA.111.00767)
Baker, A. H. and Delles, C. (2013) Is microRNA-376c a biomarker or mediator of preeclampsia? Hypertension, 61(4), pp. 767-769. (doi: 10.1161/HYPERTENSIONAHA.111.00087)
MacKenzie, R.M. et al. (2013) Mitochondrial reactive oxygen species enhance AMP-activated protein kinase activation in the endothelium of patients with coronary artery disease and diabetes. Clinical Science, 124(6), pp. 403-411. (doi: 10.1042/CS20120239)
Bryce, G.J., Payne, D.J., Gibson, S.C., Byrne, D.S., Delles, C. , McClure, J.D. and Kingsmore, D. (2013) B-type natriuretic peptide predicts postoperative cardiac events and mortality after elective open abdominal aortic aneurysm repair. Journal of Vascular Surgery, 57(2), pp. 345-353. (doi: 10.1016/j.jvs.2012.07.053)
Guo, Y., Lanktree, M. B., Taylor, K. C., Hakonarson, H., Lange, L. A., Keating, B. J., Padmanabhan, S. , Delles, C. , Dominiczak, A. F. and Hastie, C. (2013) Gene-centric meta-analyses of 108 912 individuals confirm known body mass index loci and reveal three novel signals. Human Molecular Genetics, 22(1), pp. 184-201. (doi: 10.1093/hmg/dds396) (PMID:23001569) (PMCID:PMC3522401)
Argiles, A. et al. (2013) CKD273, a new proteomics classifier assessing CKD and its prognosis. PLoS ONE, 8(5), e62837. (doi: 10.1371/journal.pone.0062837) (PMID:23690958) (PMCID:PMC3653906)
Carty, D. M., Schiffer, E. and Delles, C. (2013) Proteomics in hypertension. Journal of Human Hypertension, 27(4), pp. 211-216. (doi: 10.1038/jhh.2012.30) (PMID:22874797)
Currie, G. and Delles, C. (2013) Proteinuria and its relation to cardiovascular disease. International Journal of Nephrology and Renovascular Disease, 7, pp. 13-24. (doi: 10.2147/IJNRD.S40522) (PMID:24379690) (PMCID:PMC3873205)
Husi, H., Sanchez-Niño, M., Delles, C. , Mullen, W. , Vlahou, A., Ortiz, A. and Mischak, H. (2013) A combinatorial approach of Proteomics and Systems Biology in unravelling the mechanisms of acute kidney injury (AKI): involvement of NMDA receptor GRIN1 in murine AKI. BMC Systems Biology, 7(110), (doi: 10.1186/1752-0509-7-110)
White, K. M., Alba, R., Parker, A. L., Wright, A. F., Bradshaw, A. C. , Delles, C. , McDonald, R. A. and Baker, A. H. (2013) Assessment of a novel, capsid-modified adenovirus with an improved vascular gene transfer profile. Journal of Cardiothoracic Surgery, 8(183), (doi: 10.1186/1749-8090-8-183)
Chick, H.E. et al. (2012) Integrase-deficient lentiviral vectors mediate efficient gene transfer to human vascular smooth muscle cells with minimal genotoxic risk. Human Gene Therapy, 23(12), pp. 1247-1257. (doi: 10.1089/hum.2012.042)
MacKenzie, R.M., Sandrim, V.C., Carty, D.M., McClure, J.D. , Freeman, D.J. , Dominiczak, A.F. , McBride, M.W. and Delles, C. (2012) Endothelial FOS expression and pre-eclampsia. BJOG: An International Journal of Obstetrics and Gynaecology, 119(13), pp. 1564-1571. (doi: 10.1111/1471-0528.12016)
Asselbergs, F.W. et al. (2012) Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. American Journal of Human Genetics, 91(5), pp. 823-838. (doi: 10.1016/j.ajhg.2012.08.032)
Mischak, H. et al. (2012) Implementation of proteomic biomarkers: making it work. European Journal of Clinical Investigation, 42(9), pp. 1027-1036. (doi: 10.1111/j.1365-2362.2012.02674.x) (PMID:22519700) (PMCID:PMC3464367)
Hocking, L.J. et al. (2012) Heritability of chronic pain in 2195 extended families. European Journal of Pain, 16(7), pp. 1053-1063. (doi: 10.1002/j.1532-2149.2011.00095.x)
McInnes, I. , Lee, J.S., Thompson, L., Giles, J.T., Bathton, J.M., Salmon, J.E., Beaulieu, A.D., Codding, C.E., Delles, C. and Sattar, N. (2012) The effects of tocilizumab treatment on lipids and inflammatory/prothrombotic markers in patients (pts) with rheumatoid arthritis (RA): data from the randomized, controlled, measure study. European Heart Journal, 33(Sup 1), p. 281. (doi: 10.1093/eurheartj/ehs281)
Bryce, G.J., Payne, C.J., Gibson, S.C., Kingsmore, D.B., Byrne, D.S. and Delles, C. (2012) Risk stratification scores in elective open abdominal aortic aneurysm repair: are they suitable for preoperative decision making? European Journal of Vascular and Endovascular Surgery, 44(1), pp. 55-61. (doi: 10.1016/j.ejvs.2012.03.021)
Delles, C. , Neisius, U. and Carty, D.M. (2012) Proteomics in hypertension and other cardiovascular diseases. Annals of Medicine, 44(S1), S55-S64. (doi: 10.3109/07853890.2012.660494)
Carty, D.M., Anderson, L.A., Freeman, D.J. , Welsh, P.I. , Brennand, J.E., Dominiczak, A.F. and Delles, C. (2012) Early pregnancy soluble E-selectin concentrations and risk of preeclampsia. Journal of Hypertension, 30(5), pp. 954-959. (doi: 10.1097/HJH.0b013e328352573b)
Kane, N. M. et al. (2012) Role of MicroRNAs 99b, 181a, and 181b in the differentiation of human embryonic stem cells to vascular endothelial cells. Stem Cells, 30(4), pp. 643-654. (doi: 10.1002/stem.1026)
Carty, D.M., Anderson, L.A., Duncan, C.N., Baird, D., Rooney, L.K., Dominiczak, A.F. and Delles, C. (2012) Peripheral arterial tone: assessment of microcirculatory function in pregnancy. Journal of Hypertension, 30(1), pp. 117-123. (doi: 10.1097/HJH.0b013e32834d76fb)
Dawson, J. , Walters, M. , Delles, C. , Mischak, H. and Mullen, W. (2012) Urinary proteomics to support diagnosis of stroke. PLoS ONE, 7(5), e35879. (doi: 10.1371/journal.pone.0035879) (PMID:22615742) (PMCID:PMC3353991)
Delles, C. and Padmanabhan, S. (2012) Genetics and hypertension: is it time to change my practice? Canadian Journal of Cardiology, 28(3), pp. 296-304. (doi: 10.1016/j.cjca.2012.02.004)
Neisius, U. et al. (2012) Association of central and peripheral pulse pressure with intermediate cardiovascular phenoytpes. Journal of Hypertension, 30(1), pp. 67-74. (doi: 10.1097/HJH.0b013e32834e12d8)
Neisius, U., Schneider, M.P. and Delles, C. (2012) Association of central and peripheral pulse pressure with intermediate cardiovascular phenotypes Reply. Journal of Hypertension, 30(4), p. 835. (doi: 10.1097/HJH.0b013e328350e57c)
Johnson, T. et al. (2011) Blood pressure loci identified with a gene-centric array. American Journal of Human Genetics, 89(6), pp. 688-700. (doi: 10.1016/j.ajhg.2011.10.013)
Delles, C. , Diez, J. and Dominiczak, A.F. (2011) Urinary proteomics in cardiovascular disease: achievements, limits and hopes. Proteomics Clinical Applications, 5(5-6), pp. 222-232. (doi: 10.1002/prca.201000125)
Ott, C., Schneider, M.P., Delles, C. , Schlaich, M.P., Hilgers, K.F. and Schmieder, R.E. (2011) Association of (pro)renin receptor gene polymorphism with blood pressure in Caucasian men. Pharmacogenetics and Genomics, 21(6), pp. 347-349. (doi: 10.1097/FPC.0b013e328344cdd2)
McQuarrie, E.P., Patel, R.K., Mark, P.B. , Delles, C. , Connell, J., Dargie, H.J., Steedman, T. and Jardine, A.G. (2011) Association between proteinuria and left ventricular mass index: a cardiac MRI study in patients with chronic kidney disease. Nephrology Dialysis Transplantation, 26(3), pp. 933-938. (doi: 10.1093/ndt/gfq418)
Stevens, K.K., Morgan, I.R., Patel, R.K., Geddes, C.C., Mark, P.B. , Jardine, A.G. and Delles, C. (2011) Serum phosphate and outcome at one year after deceased donor renal transplantation. Clinical Transplantation, 25(2), E199-E204. (doi: 10.1111/j.1399-0012.2011.01400.x)
Lanktree, M. B. et al. (2011) Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height. American Journal of Human Genetics, 88(1), pp. 6-18. (doi: 10.1016/j.ajhg.2010.11.007)
Carty, D.M. et al. (2011) Urinary proteomics for prediction of preeclampsia. Hypertension, 57(3), pp. 561-569. (doi: 10.1161/HYPERTENSIONAHA.110.164285)
Mullen, W. , Delles, C. and Mischak, H. (2011) Urinary proteomics in the assessment of chronic kidney disease. Current Opinion in Nephrology and Hypertension, 20(6), pp. 654-661. (doi: 10.1097/MNH.0b013e32834b7ffa)
Mullen, W. , Gonzalez, J., Siwy, J., Franke, J., Sattar, N. , Mullan, A., Roberts, S., Delles, C. , Mischak, H. and Albalat, A. (2011) A pilot study on the effect of short-term consumption of a polyphenol rich drink on biomarkers of coronary artery disease defined by urinary proteomics. Journal of Agricultural and Food Chemistry, 59(24), pp. 12850-12857. (doi: 10.1021/jf203369r) (PMID:22070129)
Ott, C., Schneider, M. P., Delles, C. , Schlaich, M. P. and Schmieder, R. E. (2011) Reduction in Basal Nitric Oxide Activity Causes Albuminuria. Diabetes, 60(2), pp. 572-576. (doi: 10.2337/db09-1630)
Good, D. M. et al. (2010) Naturally Occurring Human Urinary Peptides for Use in Diagnosis of Chronic Kidney Disease. Molecular and Cellular Proteomics, 9(11), pp. 2424-2437. (doi: 10.1074/mcp.M110.001917)
Carty, D.M., Delles, C. and Dominiczak, A.F. (2010) Preeclampsia and future maternal health. Journal of Hypertension, 28(7), pp. 1349-1355. (doi: 10.1097/HJH.0b013e32833a39d0)
Delles, C. (2010) Angiotensinogen, birth weight and diabetes: will genetics provide a link? Journal of Hypertension, 28(4), pp. 665-667. (doi: 10.1097/HJH.0b013e328337f524)
Delles, C. , Dymott, J.A., Neisius, U., Rocchiccioli, J.P., Bryce, G.J., Moreno Zulategui, M.U., Carty, D.M., Berg, G.A., Hamilton, C.A. and Dominiczak, A.F. (2010) Reduced LDL-cholesterol levels in patients with coronary artery disease are paralelled by improved endothelial function: An observational study in patients from 2003 and 2007. Atherosclerosis, 211(1), pp. 271-277. (doi: 10.1016/j.atherosclerosis.2010.01.014)
Delles, C. and Jardine, A.G. (2010) Renal function and cardiovascular events: relevance of eGFR and albuminuria in patients with diabetes. Diabetologia, 54(1), pp. 4-6. (doi: 10.1007/s00125-010-1942-2)
Delles, C. , McBride, M.W. , Graham, D. , Padmanabhan, S. and Dominiczak, A.F. (2010) Genetics of hypertension: from experimental animals to humans. Biochimica et Biophysica Acta: Molecular Basis of Disease, 1802(12), pp. 1299-1308. (doi: 10.1016/j.bbadis.2009.12.006)
Delles, C. et al. (2010) Urinary proteomic diagnosis of coronary artery disease: identification and clinical validation in 623 individuals. Journal of Hypertension, 28(11), pp. 2316-2322. (doi: 10.1097/HJH.0b013e32833d81b7)
Dominiczak, A. F. et al. (2010) Systems biology to battle vascular disease. Nephrology Dialysis Transplantation, 25(4), pp. 1019-1022. (doi: 10.1093/ndt/gfq025)
Maahs, D.M. et al. (2010) Urinary collagen fragments are significantly altered in diabetes: a link to pathophysiology. PLoS ONE, 5(9), e13051. (doi: 10.1371/journal.pone.0013051) (PMID:20927192) (PMCID:PMC2946909)
Mischak, H., Delles, C. , Klein, J. and Schanstra, J.P. (2010) Urinary Proteomics Based on Capillary Electrophoresis-Coupled Mass Spectrometry in Kidney Disease: Discovery and Validation of Biomarkers, and Clinical Application. Advances in Chronic Kidney Disease, 17(6), pp. 493-506. (doi: 10.1053/j.ackd.2010.09.004)
Padmanabhan, S. et al. (2010) Genome-wide association study of blood pressure extremes identifies variant near UMOD associated with hypertension. PLoS Genetics, 6(10), e1001177. (doi: 10.1371/journal.pgen.1001177)
Padmanabhan, S. et al. (2010) The effects of sex and method of blood pressure measurement on genetic associations with blood pressure in the PAMELA study. Journal of Hypertension, 28(3), pp. 465-477. (doi: 10.1097/HJH.0b013e32833594d7)
Taurino, C., Miller, W.H. , McBride, M.W. , McClure, J.D. , Khanin, R., Moreno Zulategui, M.U., Dymott, J., Delles, C. and Dominiczak, A.F. (2010) Gene expression profiling in whole blood of patients with coronary artery disease. Clinical Science, 119(8), pp. 335-343. (doi: 10.1042/CS20100043)
Talmud, P. et al. (2009) Gene-centric association signals for lipids and apolipoproteins identified via the humanCVD BeadChip. American Journal of Human Genetics, 85(5), pp. 628-642. (doi: 10.1016/j.ajhg.2009.10.014)
Dominiczak, A. F. , Delles, C. and Padmanabhan, S. (2009) Are isolated populations better for studying genes that predispose to hypertension? Journal of Hypertension, 27(5), pp. 939-940. (doi: 10.1097/HJH.0b013e328329fca3) (PMCID:PMC2709222)
Delles, C. (2008) Risk factors and target organ damage: is there a special case for prehypertension? Journal of Hypertension, 26(12), pp. 2268-2270. (doi: 10.1097/HJH.0b013e328317f039)
Delles, C., McBride, M.W., Padmanabhan, S. and Dominiczak, A.F. (2008) The genetics of cardiovascular disease. Trends in Endocrinology and Metabolism, 19(9), pp. 309-316. (doi: 10.1016/j.tem.2008.07.010)
Delles, C., Raff, U., Mimran, A., Fauvel, J.P., Ruilope, L.M. and Schmieder, R.E. (2008) Effects of telmisartan and ramipril on adiponectin and blood pressure in patients with type 2 diabetes. American Journal of Hypertension, 21(12), pp. 1330-1336. (doi: 10.1038/ajh.2008.297)
Jantos-Siwy, J., Schiffer, E., Brand, K., Schumann, G., Rossing, K., Delles, C. , Mischak, H. and Metzger, J. (2008) Quantitative urinary proteome analysis for biomarker evaluation in chronic kidney disease. Journal of Proteome Research, 8(1), pp. 268-281. (doi: 10.1021/pr800401m) (PMID:19012428)
Ritt, M., Ott, C., Delles, C. , Schneider, M.P. and Schmieder, R.E. (2008) Impact of the endothelial nitric oxide synthase gene G894T polymorphism on renal endothelial function in patients with type 2 diabetes. Pharmacogenetics and Genomics, 18(8), pp. 699-707.
Delles, C. et al. (2008) Glutathione S-transferase variants and hypertension. Journal of Hypertension, 26(7), pp. 1343-1352. (doi: 10.1097/HJH.0b013e3282fe1d67)
Padmanabhan, S. , Melander, O., Hastie, C., Menni, C., Delles, C. , Connell, J. M. and Dominiczak, A. F. (2008) Hypertension and genome-wide association studies: combining high fidelity phenotyping and hypercontrols. Journal of Hypertension, 26(7), pp. 1275-1281. (doi: 10.1097/HJH.0b013e3282ff634f)
Delles, C. , Zimmerli, L., McGrane, D. J., Koh-Tan, C. H.H., Pathi, V. L., McKay, A. J., Steedman, T., Dargie, H. J., Hamilton, C. A. and Dominiczak, A. F. (2008) Vascular stiffness is related to superoxide generation in the vessel wall. Journal of Hypertension, 26(5), pp. 946-955.
Berry, C., Zimmerli, L.U., Steedman, T., Foster, J.E., Dargie, H.J., Berg, H.A., Dominiczak, A.F. and Delles, C. (2008) Cardiac magnetic resonance findings predict increased resource utilization in elective coronary artery bypass grafting. Clinical Science, 114(6), pp. 423-430. (doi: 10.1042/CS20070337)
Zimmerli, L.U. et al. (2008) Urinary proteomic biomarkers on coronary artery disease. Molecular and Cellular Proteomics, 7(2), pp. 290-298. (doi: 10.1074/mcp.M700394-MCP200)
Carty, D., Delles, C. and Dominiczak, A. (2008) Novel Biomarkers for Predicting Preeclampsia. Trends in Cardiovascular Medicine, 18(5), pp. 186-194. (doi: 10.1016/j.tcm.2008.07.002)
Delles, C. (2008) Candidate gene studies in cardiovascular medicine: complex diseases and even more complex intermediate phenotypes. Journal of Hypertension, 26(6), pp. 1069-1071.
Delles, C. , Miller, W. H. and Dominiczak, A. F. (2008) Targeting reactive oxygen species in hypertension. Antioxidants and Redox Signaling, 10(6), pp. 1061-1077. (doi: 10.1089/ars.2007.2008)
Dymott, J.A., Chow, C., Rocchiccioli, J.P., Berg, G.A., Cherry, A.K.L., Delles, C. , Hamilton, C.A. and Dominiczak, A.F. (2008) Endothelial function in patients undergoing coronary artery by-pass grafting is improved in patients in 2006 compared to 2003. Scottish Medical Journal, 53(1), p. 57.
Schneider, M. P., Delles, C. , Klingbeil, A. U., Ludwig, M., Kolloch, R. E., Krekler, M., Stumpe, K. O. and Schmieder, R. E. (2008) Effect of angiotensin receptor blockade on central haemodynamics in essential hypertension: results of a randomised trial. Journal of the Renin-Angiotensin-Aldosterone System, 9(1), pp. 49-56. (doi: 10.3317/jraas.2008.003) (PMID:18404609)
Delles, C. (2007) Mitochondria, maternal transmission and hypertension. Journal of Hypertension, 25(10), pp. 2001-2003. (doi: 10.1097/HJH.0b013e3282ef6cfa)
Delles, C. (2007) Vascular function in rheumatoid arthritis: intermediate phenotypes and cardiovascular risk. Journal of Hypertension, 25(6), pp. 1195-1196. (doi: 10.1097/HJH.0b013e3280dd8a77)
Schlaich, M.P., Oehmer, S., Schneider, M.P., Delles, C. , Schmidt, B.M.W. and Schmieder, R.E. (2007) Effects of nitric oxide synthase inhibition and L-arginine on renal haemodynamics in young patients at high cardiovascular risk. Atherosclerosis, 192(1), pp. 155-160. (doi: 10.1016/j.atherosclerosis.2006.04.025)
Schmieder, R., Delles, C. , Mimran, A., Fauvel, J. and Ruilope, L. (2007) Impact of telmisartan versus ramipri on ronal endothelial function in patients with hypertension and type 2 diabetes. Diabetes Care, 30(6), pp. 1351-1356. (doi: 10.2337/dc06-1551)
Zimmerli, L., Mark, P., Steedman, T., Foster, J., Berg, G., Dargie, H., Jardine, A., Delles, C. and Dominiczak, A. (2007) Vascular function in patients with end-stage renal disease and/or coronary artery disease: A cardiac magnetic resonance imaging study. Kidney International, 71(1), pp. 68-73. (doi: 10.1038/sj.ki.5002024)
Al Benna, S., Hamilton, C.A., McClure, J.D. , Rogers, P.N., Berg, G.A., Ford, I. , Delles, C. and Dominiczak, A.F. (2006) Low-density lipoprotein cholesterol determines oxidative stress and endothelial dysfunction in saphenous veins from patients with coronary artery disease. Arteriosclerosis, Thrombosis, and Vascular Biology, 26(1), pp. 218-223. (doi: 10.1161/01.ATV.0000193626.22269.45)
Delles, C. and Dominiczak, A. (2006) Vascular failure or sick vessel syndrome: The cardiovascular continuum is a useful concept for clinical research. Journal of Hypertension, 24(11), pp. 2147-2148. (doi: 10.1097/01.hjh.0000249687.43123.d2)
McBride, M. , Graham, D., Delles, C. and Dominiczak, A. (2006) Functional genomics in hypertension. Current Opinion in Nephrology and Hypertension, 15(2), pp. 145-151. (doi: 10.1097/01.mnh.0000203188.57513.3f)
Michelson, G., Warntges, S., Harazny, J., Oehmer, S., Delles, C. and Schmieder, R.E. (2006) Effect of NOS inhibition on retinal arterial and capillary circulation in early arterial hypertension. Retina: The Journal of Retinal and Vitreous Diseases, 26(4), pp. 437-444. (doi: 10.1097/01.iae.0000238550.74626.e5)
Oehmer, S., Harazny, J., Delles, C. , Schwarz, T., Handrock, R., Michelson, G. and Schmieder, R. (2006) Valsartan and retinal endothelial function in elderly hypertensive patients. Blood Pressure, 15(3), pp. 185-191. (doi: 10.1080/08037050600772680)
Schaufele, T., Schlaich, M., Delles, C. , Klingbeil, A., Fleischmann, E. and Schmieder, R. (2006) Impaired basal NO activity in patients with glomerular disease and the influence of oxidative stress. Kidney International, 70(6), pp. 1177-1181. (doi: 10.1038/sj.ki.5001745)
Schmidt, B., Sammer, U., Fleischmann, I., Schlaich, M., Delles, C. and Schmieder, R. (2006) Rapid nongenomic effects of aldosterone on the renal vasculature in humans. Hypertension, 47(4), pp. 650-655. (doi: 10.1161/01.HYP.0000205224.58715.cc)
Schneider, M.P., Delles, C. , Schmidt, B.M.W., Oehmer, S., Schwarz, T.K., Schmieder, R.E. and John, S. (2005) Superoxide scavenging effects of N-acetylcysteine and vitamin C in subjects with essential hypertension. American Journal of Hypertension, 18(8), pp. 1111-1117. (doi: 10.1016/j.amjhyper.2005.02.006)
John, S., Schneider, M.P., Delles, C. , Jacobi, J. and Schmieder, R.E. (2005) Lipid-independent effects of statins on endothelial function and bioavailability of nitric oxide in hypercholesterolemic patients. American Heart Journal, 149(3), 473.e1-473.e10. (doi: 10.1016/j.ahj.2004.06.02)
Dominiczak, A. F., Graham, D. , McBride, M. W. , Brain, N. J.R., Lee, W. K. , Charchar, F. J., Tomaszewski, M., Delles, C. and Hamilton, C. A. (2005) Corcoran Lecture. Cardiovascular genomics and oxidative stress. Hypertension, 45(4), pp. 636-642. (doi: 10.1161/01.HYP.0000154253.53134.09)
Schmieder, R., Klingbeil, A., Fleischmann, E., Veelken, R. and Delles, C. (2005) Additional antiproteinuric effect of ultrahigh dose candesartan: A double-blind, randomized, prospective study. Journal of the American Society of Nephrology, 16(10), pp. 3038-3045. (doi: 10.1681/ASN.2005020138)
Delles, C., Klingbeil, A.U., Schneider, M.P., Handrock, R., Schaufele, T. and Schmieder, R.E. (2004) The role of nitric oxide in the regulation of glomerular haemodynamics in humans. Nephrology Dialysis Transplantation, 19(6), pp. 1392-1397. (doi: 10.1093/ndt/gfh187)
Delles, C., Schluter, C., Wittmann, M., Renders, L., Riess, R., Rosch, W., Schott, G., Rupprecht, H. and Kunzendorf, U. (2004) 'Very delayed' graft function in a patient after living related kidney transplantation: A case report. Transplantation Proceedings, 36(5), pp. 1377-1379. (doi: 10.1016/j.transproceed.2004.05.015)
Delles, C., Schluter, C., Wittmann, M., Renders, L., Riess, R., Rosch, W., Schott, G., Rupprecht, H. and Kunzendorf, U. (2004) "Very delayed" graft function in a patient after living related kidney transplantation: A case report. Transplantation Proceedings, 36, pp. 1377-1379. (doi: 10.1016/j.transproceed.2004.05.015)
Delles, C. and Schmieder, R. (2004) Effects of the angiotensin-1 receptor blocker valsartan compared with amlodipine on renal hemodynamics - Reply. American Journal of Hypertension, 17(7), pp. 639-640.
Delles, C. and Schmieder, R. (2004) Is the afferent arteriole the main location of nitric oxide action and synthesis in humans? Reply. Nephrology Dialysis Transplantation, 19(11), pp. 2925-2926.
Delles, C. and Schmieder, R. (2004) Renal endothelial effects of anti hypertensive therapy. Current Opinion in Nephrology and Hypertension, 13(5), pp. 489-493.
Delles, C. , Michelson, G., Harazny, J., Oehmer, S., Hilgers, K.F. and Schmieder, R.E. (2004) Impaired endothelial function of the retinal vasculature in hypertensive patients. Stroke, 35(6), pp. 1289-1293. (doi: 10.1161/01.STR.0000126597.11534.3b)
Delles, C. , Schneider, M., Oehmer, S., Fleischmann, I., Fleischmann, E.F. and Schmeider, R.E. (2004) Increased response of renal perfusion to the antioxidant vitamin C in type 2 diabetes. Nephrology Dialysis Transplantation, 19(10), pp. 2513-2518. (doi: 10.1093/ndt/gfh405)
Fleischmann, E.H., John, S., Delles, C. , Schneider, M.P., Schmidt, B.M.W. and Schmieder, R.E. (2004) The effect of statins on angiotensin II-induced hemodynamic changes in young, mildly hypercholesterolemic men. American Journal of Hypertension, 17(12), pp. 1120-1126. (doi: 10.1016/j.amjhyper.2004.07.011)
Schneider, M.P., Klingbeil, A.U., Delles, C., Ludwig, M., Kolloch, R.E., Krekler, M., Stumpe, K.O. and Schmieder, R.E. (2004) Effect of irbesartan versus atenolol on left ventricular mass and voltage: results of the Cardio Vascular Irbesartan Project. Hypertension, 44(1), pp. 61-66. (doi: 10.1161/01.HYP.0000133249.28773.d7)
Delles, C. , Klingbeil, A.U., Schneider, M.P., Handrock, R., Schmieder, R.E. and Weidinger, G. (2003) Direct comparison of the effects of valsartan and amlodipine on renal hemodynamics in human essential hypertension. American Journal of Hypertension, 16(12), pp. 1030-1035. (doi: 10.1016/j.amjhyper.2003.07.017)
Schneider, M.P., Klingbeil, A.U., Delles, C. , Schmidt, B.M.W., John, S. and Schmieder, R.E. (2003) Vitamin C augments the renal response to L-arginine in smokers. Nephrology Dialysis Transplantation, 18(8), pp. 1512-1517. (doi: 10.1093/ndt/gfg195)
Delles, C. , Schneider, M.P., Oehmer, S., Fleischmann, E.H. and Schmieder, R.E. (2003) L-arginine-induced vasodilation of the renal vasculature is not altered in hypertensive patients with type 2 diabetes. Diabetes Care, 26(6), pp. 1836-1840. (doi: 10.2337/diacare.26.6.1836)
Schneider, M.P., Delles, C. , Fleischmann, E., Schmidt, B.M.W., John, S. and Schmieder, R.E. (2003) Effect of elevated triglyceride levels on endothelium-dependent vasodilation in patients with hypercholesterolemia. American Journal of Cardiology, 91(4), pp. 482-484. (doi: 10.1016/S0002-9149(02)03255-1)
Delles, C. , Schmidt, B., Muller, H., Oehmer, S., Klingbeil, A. and Schmieder, R. (2003) Functional relevance of aldosterone for the determination of left ventricular mass. American Journal of Cardiology, 91(3), pp. 297-301. (doi: 10.1016/S0002-9149(02)03158-2)
Delles, C. and Schmieder, R. (2003) Endothelial function of the human renal vasculature. Deutsche Medizinische Wochenschrift, 128(3), pp. 92-96.
Schmidt, B.M.W., Oehmer, S., Delles, C. , Bratke, R., Schneider, M.P., Klingbeil, A., Fleischmann, E.H. and Schmieder, R.E. (2003) Rapid nongenomic effects of aldosterone on human forearm vasculature. Hypertension, 42(2), pp. 156-160. (doi: 10.1161/01.HYP.0000083298.23119.16)
Schneider, M.P., Hilgers, K.F., Huang, Y., Delles, C. , John, S., Oehmer, S. and Schmieder, R.E. (2003) The C242T p22phox polymorphism and endothelium-dependent vasodilation in subjects with hypercholesterolaemia. Clinical Science, 105(1), pp. 97-103. (doi: 10.1042/CS20030003)
Schlaich, M.P., Klingbeil, A.U., Jacobi, J., Delles, C. , Schneider, M.P., Schmidt, B.M. and Schmieder, R.E. (2002) Altered aldosterone response to salt intake and angiotensin II infusion in young normotensive men with parental history of arterial hypertension. Journal of Hypertension, 20(1), pp. 117-24.
Delles, C. , Jacobi, J., John, S., Fleischmann, I. and Schmieder, R. (2002) Effects of enalapril and eprosartan on the renal vascular nitric oxide system in human essential hypertension. Kidney International, 61(4), pp. 1462-1468. (doi: 10.1046/j.1523-1755.2002.00260.x)
Delles, C. , Jacobi, J., Schlaich, M., John, S. and Schmieder, R. (2002) Assessment of endothelial function of the renal vasculature in human subjects. American Journal of Hypertension, 15(1), pp. 3-9. (doi: 10.1016/S0895-7061(01)02242-7)
Delles, C. , Schneider, M., John, S., Gekle, M. and Schmieder, R. (2002) Angiotensin converting enzyme inhibition and angiotensin II AT(1)-receptor blockade reduce the levels of asymmetrical N-G, N-G-dimethylarginine in human essential hypertension. American Journal of Hypertension, 15(7), pp. 590-593. (doi: 10.1016/S0895-7061(02)02278-1)
Delles, C. , Weidner, S., Schobel, H. and Rupprecht, H. (2002) Renal-artery stenosis in a patient with Takayasu's arteritis. Nephrology Dialysis Transplantation, 17(7), pp. 1339-1341. (doi: 10.1093/ndt/17.7.1339)
Delles, C. , Wittmann, M., Renders, L., Kunzendorf, U., Bohner, C., Wutke, R., Lang, W., Schott, G. and Rupprecht, H. (2002) Restoration of renal allograft function by endovascular stenting of an iliac artery dissection. Nephrology Dialysis Transplantation, 17(6), pp. 1116-1118. (doi: 10.1093/ndt/17.6.1116)
Zeltner, R., Delles, C. , Schneider, M., Siffert, W. and Schmieder, R.E. (2001) G-protein beta(3) subunit gene (GNB3) 825T allele is associated with enhanced renal perfusion in early hypertension. Hypertension, 37(3), pp. 882-886. (doi: 10.1161/01.HYP.37.3.882)
Delles, C. , Erdmann, J., Jacobi, J., Hilgers, K., Fleck, E., Regitz-Zagrosek, V. and Schmieder, R. (2001) Aldosterone synthase (CYP11B2)-344 C/T polymorphism is associated with left ventricular structure in human arterial hypertension. Journal of the American College of Cardiology, 37(3), pp. 878-884. (doi: 10.1016/S0735-1097(00)01174-8)
Delles, C. and Schmieder, R. (2001) The kidney in congestive heart failure: Renal adverse event rate of treatment. Journal of Cardiovascular Pharmacology, 38(1), pp. 99-107.
Hilgers, K., Delles, C. , Veelken, R. and Schmieder, R. (2001) Angiotensinogen gene core promoter variants and non-modulating hypertension. Hypertension, 38(6), pp. 1250-1254. (doi: 10.1161/hy1201.096545)
John, S., Delles, C., Jacobi, J., Schlaich, M.P., Schneider, M., Schmitz, G. and Schmieder, R.E. (2001) Rapid improvement of nitric oxide bioavailability after lipid-lowering therapy with cerivastatin within two weeks. Journal of the American College of Cardiology, 37(5), pp. 1351-1358. (doi: 10.1016/S0735-1097(01)01128-7)
Leidig, M., Delles, C. , Kuchenbecker, C., Lederle, X., Weidinger, G. and Schmieder, R. (2001) Pharmacokinetics of valsartan in hypertensive patients on long-term haemodialysis. Clinical Drug Investigation, 21(1), pp. 59-66. (doi: 10.2165/00044011-200121010-00008)
Schmieder, R., Erdmann, J., Delles, C. , Jacobi, J., Fleck, E., Hilgers, K. and Regitz-Zagrosek, V. (2001) Effect of the angiotensin II type 2-receptor gene (+1675 G/A) on left ventricular structure in humans. Journal of the American College of Cardiology, 37(1), pp. 175-182. (doi: 10.1016/S0735-1097(00)01063-9)
Schneider, M., Erdmann, J., Delles, C. , Fleck, E., Regitz-Zagrosek, V. and Schmieder, R. (2001) Functional gene testing of the Glu298Asp polymorphism of the endothelial nitric oxide synthase - Reply. Journal of Hypertension, 19(7), pp. 1341-1342.
Veelken, R., Delles, C. , Hilgers, K. and Schmieder, R. (2001) Outcome survey in unselected hypertensive patients with type 2 diabetes mellitus: effects of ACE inhibition. American Journal of Hypertension, 14(7), pp. 672-678. (doi: 10.1016/S0895-7061(01)01300-0)
Book Sections
Mary, S. , Currie, G. , Schutte, A. E. and Delles, C. (2020) Cardiovascular proteomics. In: Faintuch, J. and Faintuch, S. (eds.) Precision Medicine for Investigators, Practitioners and Providers. Academic Press: London ; San Diego, CA, pp. 263-270. ISBN 9780128191781 (doi: 10.1016/b978-0-12-819178-1.00025-3)
Ravassa, S., Delles, C. , Currie, G. and Díez, J. (2019) Biomarkers of cardiovascular disease. In: Touyz, R. M. and Delles, C. (eds.) Textbook of Vascular Medicine. Springer: Cham, pp. 319-330. ISBN 9783030164805 (doi: 10.1007/978-3-030-16481-2_30)
Small, H. Y., Currie, G. and Delles, C. (2019) Endothelial dysfunction. In: Touyz, R. M. and Delles, C. (eds.) Textbook of Vascular Medicine. Springer: Cham, pp. 183-192. ISBN 9783030164805 (doi: 10.1007/978-3-030-16481-2_17)
Delles, C. and Husi, H. (2017) Systems biology approach in hypertension research. In: Touyz, R. M. and Schriffin, E. L. (eds.) Hypertension: Methods and Protocols. Series: Methods in molecular biology, 1527. Springer: New York, pp. 69-79. ISBN 9781493966233 (doi: 10.1007/978-1-4939-6625-7_6)
Currie, G. , Matt, P. and Delles, C. (2016) Clinical cardiovascular proteomics. In: Agnetti, G., Lindsey, M. L. and Foster, D. B. (eds.) Manual of Cardiovascular Proteomics. Springer, pp. 389-414. ISBN 9783319318264 (doi: 10.1007/978-3-319-31828-8_17)
Delles, C. and Dominiczak, A. F. (2013) Metabolic alterations. In: Mancia, G. (ed.) Resistant Hypertension : Epidemiology, Pathophysiology, Diagnosis and Treatment. Springer, pp. 23-37. ISBN 9788847054158 (doi: 10.1007/978-88-470-5415-8_3)
Delles, C. and Dominiczak, A. F. (2010) Redox-related genetic markers of cardiovascular diseases. In: Sauer, H., Shah, A.M. and Laurindo, F.R.M. (eds.) Studies on Cardiovascular Disorders. Series: Oxidative stress in applied basic research and clinical practice. Humana Press, pp. 187-209. ISBN 9781607615996 (doi: 10.1007/978-1-60761-600-9_10)
Edited Books
Touyz, R. M. and Delles, C. (Eds.) (2019) Textbook of Vascular Medicine. Springer: Cham. ISBN 9783030164805
Conference or Workshop Item
Setjiadi, D., Delles, C. , Boutouyrie, P. and Bruno, R. M. (2024) Inappropriate Pulse Wave Velocity to Blood Pressure Level: Definition and Clinical Determinants. 26th Meeting of the European Council for Cardiovascular Research, Online, 24-25 Nov 2023. A1-A42.
Setjiadi, D., Delles, C. , Currie, G. and Celis-Morales, C. A. (2023) Relationship between blood pressure level and hypertensive mediated organ damage. The 26th Annual Meeting of the Scottish Cardiovascular Forum, Aberdeen, UK, 04 Feb 2023. A2.1-A2. (doi: 10.1136/heartjnl-SCF-2023.4)
Kohli-Lynch, C.N. , Boyd, K. , Briggs, A. and Delles, C. (2017) A Framework for the Cost-Effectiveness Analysis of Novel Biomarker Testing in Cardiovascular Disease. ISPOR 20th Annual European Congress, Glasgow, UK, 4-8 Nov 2017. A404-A405. (doi: 10.1016/j.jval.2017.08.040)
Grants
Grants and Awards listed are those received whilst working with the University of Glasgow.
- Cross disciplinary capacity building in ultra-high frequency preclinical cardiovascular ultrasound
British Heart Foundation
2022 - 2025
- Preconception study of Outcomes in Primiparous PregnancY (POPPY)
Wellcome Trust
2022 - 2027
- Vascular Stiffness in the Pathogenesis of Pre-eclampsia
Canadian Institutes of Health Research
2021 - 2024
- Vascular effects of SARS-CoV-2 infection and long term impact on hypertension
Heart Research UK
2021 - 2024
- MINDSHIFT
European Commission
2021 - 2025
- Investigation of Uromodulin Polymerisation in Development And Progression Of Hypertension
Academy of Medical Sciences
2018 - 2019
- Vaso-protective properties of maternal high density lipoprotein (HDL) in metabolic complications of pregnancy
NHS Greater Glasgow and Clyde Endowment Funds
2018 - 2019
- Diabetes, Glucose Lowering and Preeclampsia Prevention: The Role of Vascular Function
Glasgow Children`s Hospital Charity
2017 - 2019
- The African Prospective study on the Early Detection and Identification of Cardiovascular disease and Hypertension (African-PREDICT)
Medical Research Council
2016 - 2020
- Combined Suppression of cholesterol bioavailability and androgen de novo syntheseis to treat castrate resistant prostate cancer
Prostate Cancer UK
2015 - 2019
- Metabolite and protein profiling in CADASIL to unravel the vascular pathophysiology and natural history
NHS Greater Glasgow and Clyde Endowment Funds
2014 - 2016
- Systems biology analysis of multi-omics data and development of integrative analysis methods for biomarkers and determinants of treatment-refractory severe asthma (ISSF Catalyst)
Wellcome Trust
2014 - 2015
- Therapeutic manipulation of miR-214
Medical Research Council
2014 - 2015
- BHF centre of excellence
British Heart Foundation
2014 - 2019
- DISCHARGE
European Commission
2014 - 2019
- Studies into the role of microparticles in cardiovascular diseases
Ministry of Education and Science of the Russian Federation
2014 - 2014
- SysVasc
European Commission
2014 - 2018
- Characterising vascular pathophysiology in CADASIL (cerebral autosomal dominant arteriopathy with subacute infarcts and leukoencephalopathy) by evaluation of gluteal resistance vessels
Stroke Association
2013 - 2016
- IMODE-CKD: Clinical and system-omics for the identification of the Molecular Determinants of established Chronic Kidney Disease
European Commission
2013 - 2017
- Understanding variability in phenotype, and assessing the risk of serious cardiac events, in women and children with long QT syndrome.
Glasgow Children`s Hospital Charity
2013 - 2015
- HOMAGE: Heart OMics in AGEing
European Commission
2013 - 2019
- Cerebral and peripheral perfusion and reactivity in CADASIL: a longitudinal pilot study
Chief Scientist Office
2013 - 2016
- Cardiovascular consequences of preeclampsia in women from the Generation Scotland: Scottish Family Health Study.
Chief Scientist Office
2012 - 2015
- Inhibition of vascular Stat Signalling by Amp-Activated Protein Kinase (AMPK).
British Heart Foundation
2012 - 2015
- Serum phosphate as a cardiovascular risk factor: effects on vascular and endothelial function
British Heart Foundation
2012 - 2013
- PRIORITY: Intervention study for the prevention of diabetic nephropathy
European Commission
2012 - 2017
- EU-MASCARA - Biomarkers for Cardiovascular Disease
European Commission
2011 - 2015
- Reversal of pro-inflammatory interleukin-6 signalling by cyclic AMP-mediated induction of suppressor of cytokine signalling-3(SOCS-3)
Chest Heart and Stroke Scotland
2010 - 2011
- Euratrans
European Commission
2010 - 2014
- InGenious HyperCare - Integrating Genomics, Clinical Research and Care in Hypertension
European Commission
2009 - 2010
- Induced pluripoptent cells: analysis of cell reprogramming of dermal fibroblasts derived from patients with disease vs age-matched healthy controls
British Heart Foundation
2009 - 2012
- Researcher Exchange from Faculdade de Medicina de Ribeirao Preto, Brazil
British Council - Manchester
2009 - 2009
- EPAC1 and ERK-dependent activation of C/EBP transcription factors: a new cyclic AMP-activated anti-inflammatory gene expression module in vascular endothelial cells
British Heart Foundation
2009 - 2011
- Collaborative strategy for a definitive genome scan in essential hypertension: high fidelity phenotyping and "hypercontrols"
British Heart Foundation
2008 - 2011
- Genomics and proteomics of hypertension and its vascular complications: the pathwayomic strategies.
British Heart Foundation
2008 - 2011
- Assessment of endothelial function in pregnancy: evaluation of a non-invasive method to analyse flow-mediated vasodilation
NHS Greater Glasgow and Clyde Endowment Funds
2008 - 2010
- High throughput collaborative analysis of cardiovascular genes in 6000 hypertensives and 6000 controls
British Heart Foundation
2008 - 2009
- Hydralazine in heart failure - a study of the mechanisms of action in human blood vessels
British Heart Foundation
2006 - 2009
Supervision
- Adu, Samuel
Vascular redox signalling and protein oxidation in hypertens - Parveen, Humaira
Investigating the role of endoplasmic reticulum stress - Soudant, Julius
ISG15 is a novel mediator of vascular damage in hypertension - Wang, Kai
Metabolic drivers of hypertension: focus on the microcirculation
Teaching
Christian teaches on the School’s and College’s PGT programmes including the MSc Cardiovascular Sciences where he regularly supervises student projects. At undergraduate levels he contributes to Honours project supervision across the Life Sciences portfolio, teaches Medical students and supervises BSc (Med Sci) students. He chairs the University's Clinical Academic Training Advisory Committee.