Kidney Disease

We aim to improve the health for people with, or at risk of kidney disease by addressing its impact on cardiovascular disease, cancer, infection, quality of life and survival.

Staff

Publications

2024

Lees, J. S., Fabian, J., Shlipak, M. G. (2024) Cystatin C should be routinely available for estimating kidney function. Current Opinion in Nephrology and Hypertension, 33, pp. 337-343. (doi: 10.1097/MNH.0000000000000980)

Lang, N., Rankin, S., Elyan, B., Jones, R., Venugopal, B., Mark, P. B., Lees, J., Petrie, M., Lang, N. (2024) Cardiovascular eligibility criteria and adverse event reporting in combined immune checkpoint and VEGF inhibitors trials. JACC: CardioOncology, 6, pp. 267-279. (doi: 10.1016/j.jaccao.2023.12.010)

Mayne, K. J., Hanlon, P., Lees, J. (2024) Detecting and managing the patient with CKD in primary care: a review of the latest guidelines. Diabetes, Obesity and Metabolism,

Carberry, J., Petrie, M. C., Lee, M. M.Y., Brooksbank, K., Campbell, R. T., Good, R., Jhund, P. S., Kellman, P., Lang, N. N., Mangion, K., Mark, P. B., McConnachie, A., McMurray, J. J.V., Meyer, B., Orchard, V., Shaukat, A., Watkins, S., Welsh, P., Sattar, N., Berry, C., Docherty, K. F. (2024) Empagliflozin to prevent progressive adverse remodelling after myocardial infarction (EMPRESS-MI): rationale and design. ESC Heart Failure,

Rastogi, T., Gargani, L., Pellicori, P., Lamiral, Z., Ambrosio, G., Bayés-Genis, A., Domingo, M., Lupon, J., Simonovic, D., Riccardo Pugliese, N., Ruocco, G., Duarte, K., Coiro, S., Palazzuoli, A., Girerd, N. (2024) Prognostic implication of lung ultrasound in heart failure: pooled analysis of international cohorts. European Heart Journal: Cardiovascular Imaging,

Stoumpos, S., van Rhijn, P., Mangion, K., Thomson, P. C., Mark, P. B. (2024) Arteriovenous fistula for haemodialysis as a predictor of de novo heart failure in kidney transplant recipients. Clinical Kidney Journal,

Hanson Ng, Y. Y., Dora, K. A., Lemmey, H. A. L., Lin, J., Alden, J., Wallis, L., Donovan, L., Shorthose, O., Leiper, F. C., Leiper, J., Garland, C. J. (2024) Asymmetric dimethylarginine enables depolarizing spikes and vasospasm in mesenteric and coronary resistance arteries. Hypertension, 81, pp. 764-775. (doi: 10.1161/HYPERTENSIONAHA.123.22454)

Chen, D. C., Lu, K., Scherzer, R., Lees, J. S., Rutherford, E., Mark, P. B., Potok, O. A., Rifkin, D. E., Ix, J. H., Shlipak, M. G., Estrella, M. M. (2024) Cystatin C- and creatinine-based estimated GFR differences: prevalence and predictors in the UK Biobank. Kidney Medicine, 6, (doi: 10.1016/j.xkme.2024.100796)

Lim, M. W. S., Lucas-Herald, A. K., Mason, A., Delles, C., Connelly, P. J. (2024) Sex differences in the cardiovascular effects of GnRH analogues. Journal of Endocrinology, 261, (doi: 10.1530/JOE-23-0309)

Docherty, K. F., McMurray, J. J.V., Kalra, P., Cleland, J. G.F., Lang, N. N., Petrie, M. C., Robertson, M., Ford, I. (2024) Intravenous iron and SGLT2 inhibitors in iron-deficient patients with heart failure and reduced ejection fraction. ESC Heart Failure, (doi: 10.1002/ehf2.14742)

Del Vecchio, L., Girelli, D., Vinchi, F., Cozzolino, M., Elliott, S., Mark, P. B., Valenti, L., Qian, C., Guo, Q., Qian, Z.-M., Ciceri, P., Locatelli, F. (2024) Iron biology in chronic kidney disease: not just anaemia. Nephrology Dialysis Transplantation,

Shemilt, R., Sullivan, M.K., Hanlon, P., Jani, B., De La Mata, N., Rosales, B., Elyan, B.M.P., Hedley, J.A., Cutting, R.B., Wyld, M., McAllister, D.A., Webster, A.C., Mark, P.B., Lees, J.S. (2024) Sex differences in cancer outcomes across the range of eGFR. Nephrology Dialysis Transplantation, (doi: 10.1093/ndt/gfae059)

Kobayashi, M., Ferreira, J. P., Kevin, D., Bresso, E., Huttin, O., Bozec, E., Brunner La Rocca, H.-P., Delles, C., Clark, A. L., Edelmann, F., González, A., Heymans, S., Pellicori, P., Petutschnigg, J., Verdonschot, J. A.J., Rossignol, P., Cleland, J. G.F., Zannad, F., Girerd, N. (2024) Proteomic profiles of left atrial volume and its influence on response to spironolactone: findings from the HOMAGE trial and STANISLAS cohort. European Journal of Heart Failure,

Cleland, J. G.F., Kalra, P. A., Pellicori, P., Graham, F. J., Foley, P. W.X., Squire, I. B., Cowburn, P. J., Seed, A., Clark, A. L., Szwejkowski, B., Banerjee, P., Cooke, J., Francis, M., Clifford, P., Wong, A., Petrie, C., McMurray, J. J.V., Thomson, E. A., Wetherall, K., Robertson, M., Ford, I., Kalra, P. R. (2024) Intravenous iron for heart failure, iron deficiency definitions, and clinical response: the IRONMAN trial. European Heart Journal, (doi: 10.1093/eurheartj/ehae086)

Grobbee, D. E., Filippatos, G., Desai, N. R., Coats, A. J.S., Pinto, F., Rosano, G. M.C., Cleland, J., Kammerer, J., Ramirez de Arellano, A. (2024) Epidemiology and risk factors for hyperkalaemia in heart failure. ESC Heart Failure, (doi: 10.1002/ehf2.14661)

Olowoyo, P. et al. (2024) ACHIEVE conference proceedings: implementing action plans to reduce and control hypertension burden in Africa. Journal of Human Hypertension, 38, pp. 193-199. (doi: 10.1038/s41371-024-00903-8)

Adamson, W. E., Noyes, H., Johnson, P., Cooper, A., Monckton, D. G., Ogunsola, J., Beckett-Hill, G., Sullivan, M., Mark, P., Parekh, R. S., MacLeod, A. (2024) Phenome-wide analysis reveals epistatic associations between APOL1 variants and chronic kidney disease and multiple other disorders. EBioMedicine, 101, (doi: 10.1016/j.ebiom.2024.105000)

Balafa, O., Fernandez-Fernandez, B., Ortiz, A., Dounousi, E., Ekart, R., Ferro, C. J., Mark, P. B., Valdivielso, J. M., Del Vecchio, L., Mallamaci, F. (2024) Sex disparities in mortality and cardiovascular outcomes in chronic kidney disease. Clinical Kidney Journal, 17, (doi: 10.1093/ckj/sfae044)

Morrow, A. J. et al. (2024) Socioeconomic deprivation and illness trajectory in the Scottish population after COVID-19 hospitalization. Communications Medicine, 4, (doi: 10.1038/s43856-024-00455-5)

Lean, M. E.J., Leslie, W. S., Barnes, A. C., Brosnahan, N., Thom, G., McCombie, L., Kelly, T., Irvine, K., Peters, C., Zhyzhneuskaya, S., Hollingsworth, K. G., Adamson, A. J., Sniehotta, F. F., Mathers, J. C., McIlvenna, Y., Welsh, P., McConnachie, A., McIntosh, A., Sattar, N., Taylor, R. (2024) 5-year follow-up of the randomised Diabetes Remission Clinical Trial (DiRECT) of continued support for weight loss maintenance in the UK: an extension study. Lancet Diabetes and Endocrinology, (doi: 10.1016/S2213-8587(23)00385-6)

Denicolò, S., Reinstadler, V., Keller, F., Thöni, S., Eder, S., Heerspink, H. J.L., Rosivall, L., Wiecek, A., Mark, P. B., Perco, P., Leierer, J., Kronbichler, A., Oberacher, H., Mayer, G. (2024) Non-adherence to antidiabetic and cardiovascular medication as assessed by LC-MS/MS in urine and its association with kidney and cardiovascular outcomes in type 2 diabetes mellitus. Diabetologia,

Rossitto, G., Bertoldi, G., Rutkowski, J. M., Mitchell, B. M., Delles, C. (2024) Sodium, interstitium, lymphatics, and hypertension - A tale of hydraulics: Salt series. Hypertension, (doi: 10.1161/HYPERTENSIONAHA.123.17942)

Loughrey, C. et al. (2024) A novel ryanodine receptor 2 inhibitor, M201-A, enhances natriuresis, renal function and lusi-inotropic action: Pre-clinical and phase I study. British Journal of Pharmacology,

Pellicori, P., Felker, G. M., Cleland, J. G.F. (2024) Reply to ‘Vasodilators in congestive heart failure: The perfect weapon aiming just off the target?’ European Journal of Heart Failure, 26, pp. 528-528. (doi: 10.1002/ejhf.3159)

Heerspink, H. J.L., Provenzano, M., Vart, P., Jongs, N., Correa-Rotter, R., Rossing, P., Mark, P. B., Pecoits-Filho, R., McMurray, J. J.V., Langkilde, A. M., Wheeler, D. C., Toto, R. B., Chertow, G. M. (2024) Dapagliflozin and blood pressure in patients with chronic kidney disease and albuminuria. American Heart Journal, (doi: 10.1016/j.ahj.2024.02.006)

Friedman, D. J., Olivas-Martinez, A., Dalgaard, F., Fudim, M., Abraham, W. T., Cleland, J. G.F., Curtis, A. B., Gold, M. R., Kutyifa, V., Linde, C., Tang, A. S., Ali-Ahmed, F., Inoue, L. Y.T., Sanders, G. D., Al-Khatib, S. M. (2024) Relationship between sex, body size, and cardiac resynchronization therapy benefit: a patient level meta-analysis of randomized controlled trials. Heart Rhythm, (doi: 10.1016/j.hrthm.2024.01.058)

Lakhal-Littleton, S., Cleland, J. G. F. (2024) Iron deficiency and supplementation in heart failure. Nature Reviews Cardiology, (doi: 10.1038/s41569-024-00988-1)

Welsh, P., Al Zabiby, A., Byrne, H., Benbow, H. R., Itani, T., Farries, G., Costa-Scharplatz, M., Ferber, P., Martin, L., Brown, R., Fonseca, A. F., Sattar, N. (2024) Elevated lipoprotein(a) increases risk of subsequent major adverse cardiovascular events (MACE) and coronary revascularisation in incident ASCVD patients: a cohort study from the UK biobank. Atherosclerosis, 389, (doi: 10.1016/j.atherosclerosis.2023.117437)

Chybowska, A. D., Gadd, D. A., Cheng, Y., Bernabeu, E., Campbell, A., Walker, R. M., McIntosh, A. M., Wrobel, N., Murphy, L., Welsh, P., Sattar, N., Price, J. F., McCartney, D. L., Evans, K. L., Marioni, R. E. (2024) Epigenetic contributions to clinical risk prediction of cardiovascular disease. Circulation: Genomic and Precision Medicine, 17, (doi: 10.1161/CIRCGEN.123.004265)

Ammirati, E., Marchetti, D., Colombo, G., Pellicori, P., Gentile, P., D’Angelo, L., Masciocco, G., Verde, A., Macera, F., Brunelli, D., Occhi, L., Musca, F., Perna, E., Bernasconi, D. P., Moreo, A., Camici, P., Metra, M., Oliva, F., Garascia, A. (2024) Estimation of right atrial pressure by ultrasound-assessed jugular vein distensibility in patients with heart failure. Circulation: Heart Failure, 17, (doi: 10.1161/CIRCHEARTFAILURE.123.010973)

Bull, C. J. et al. (2024) Impact of weight loss on cancer-related proteins in serum: results from a cluster randomised controlled trial of individuals with type 2 diabetes. EBioMedicine, 100, (doi: 10.1016/j.ebiom.2024.104977)

Olowoyo, P. et al. (2024) Priorities to reduce the burden of hypertension in Africa through ACHIEVE. Lancet Global Health, 12, pp. e192-e193. (doi: 10.1016/S2214-109X(23)00540-5)

Pellicori, P., Cleland, J. G.F. (2024) Atrial myopathy and heart failure with preserved ejection fraction: When a label does more harm than good? European Journal of Heart Failure, (doi: 10.1002/ejhf.3148)

Mary, S., Conti-Ramsden, F., Boder, P., Parveen, H., Setjiadi, D., Fleminger, J., Brockbank, A., Graham, D., Bramham, K., Chappell, L. C., Delles, C. (2024) Pregnancy-associated changes in urinary uromodulin excretion in chronic hypertension. Journal of Nephrology, (doi: 10.1007/s40620-023-01830-6)

Cuthbert, J. J., Brown, O. I., Pellicori, P., Dobbs, K., Bulemfu, J., Kazmi, S., Sokoreli, I., Pauws, S. C., Riistama, J. M., Cleland, J. G.F., Clark, A. L. (2024) Medicines optimization prior to discharge in patients admitted to hospital with heart failure. ESC Heart Failure, (doi: 10.1002/ehf2.14638)

Pellicori, P., Hunter, D., Khin, H. H. E., Cleland, J. G.F. (2024) How to diagnose and treat venous congestion in heart failure. European Heart Journal, (doi: 10.1093/eurheartj/ehad883)

Kharlamov, A., Sherriff, N., Delles, C., van der Harst, P. (2024) Tackling cardiovascular healthcare disparities for LGBTQIA+ population: a call to action in the European Society of Cardiology. European Heart Journal, (doi: 10.1093/eurheartj/ehad882)

Pellicori, P., Cleland, J. G.F. (2024) Atrial myopathy and HFpEF - when a label does more harm than good. European Journal of Heart Failure,

Sidik, N. P., Stanley, B., Sykes, R., Morrow, A. J., Bradley, C. P., Mcdermott, M., Ford, T., Roditi, G., Hargreaves, A., Stobo, D., Adams, J., Byrne, J., Mahrous, A., Young, R., Carrick, D., McGeoch, R., Corcoran, D., Lang, N. N., Heggie, R., Wu, O., McEntegart, M. B., McConnachie, A., Berry, C. (2024) Invasive endotyping in patients with angina and no obstructive coronary artery disease: a randomized controlled trial. Circulation, 149, pp. 7-23. (doi: 10.1161/CIRCULATIONAHA.123.064751)

Zeitler, E. P., Dalgaard, F., Abraham, W. T., Cleland, J. G.F., Curtis, A. B., Friedman, D. J., Gold, M. R., Kutyifa, V., Linde, C., Tang, A. S., Olivas-Martinez, A., Inoue, L. Y.T., Sanders, G. D., Al-Khatib, S. M. (2024) Benefit of cardiac resynchronization therapy among older patients: A patient-level meta-analysis. American Heart Journal, 267, pp. 81-90. (doi: 10.1016/j.ahj.2023.11.002)

Hanlon, P., Welsh, S. A., Evans, N. R. (2024) Constructing a quality frailty index: you get out what you put in. Age and Ageing, 53, (doi: 10.1093/ageing/afad248)

Cleland, J. G. F. (2024) Defining iron deficiency in patients with heart failure. Nature Reviews Cardiology, 21, pp. 1-2. (doi: 10.1038/s41569-023-00951-6)

Sofianopoulou, E. et al. (2024) Estimating dose—response relationships for vitamin D with coronary heart disease, stroke, and all-cause mortality: observational and revised Mendelian randomization analyses. Lancet Diabetes and Endocrinology, 12, pp. E2-E11. (doi: 10.1016/S2213-8587(23)00287-5)

McFall, A., Graham, D., Nicklin, S. A., Work, L. M. (2024) Unscheduled changes in pre-clinical stroke model housing contributes to variance in physiological and behavioural data outcomes: a post hoc analysis. Brain and Neuroscience Advances, 8, (doi: 10.1177/23982128241238934)

Monzo, L., Girerd, N., Ferreira, J. P., Lamiral, Z., Anker, S. D., Cleland, J. G. F., Kondo, T., McMurray, J. J. V., Lam, C. S. P., Mehra, M. R., van Veldhuisen, D. J., Greenberg, B., Zannad, F. (2024) High risk of stroke in patients with worsening heart failure, reduced ejection fraction, coronary heart disease and sinus rhythm: risk prediction score analysis from the COMMANDER-HF trial. Journal of Cardiac Failure, (doi: 10.1016/j.cardfail.2023.11.020)

2023

Caiazzo, E., Sharma, M., Rezig, A. O.M., Morsay, M. I., Czesnikiewicz-Guzik, M., Ialenti, A., Sulicka-Grodzicka, J., Pellicori, P., Crouch, S. H., Schutte, A. E., Bruzzese, D., Maffia, P., Guzik, T. J. (2023) Circulating cytokines and risk of developing hypertension: a systematic review and meta-analysis. Pharmacological Research, 200, (doi: 10.1016/j.phrs.2023.107050)

Glen, C., Adam, S., Coats, C. J., Lang, N. N. (2023) Reply: Cardiotoxicity of BRAF/MEK inhibitors according to HFA/ICOS cardiotoxicity risk category. JACC: CardioOncology, 5, pp. 850. (doi: 10.1016/j.jaccao.2023.10.003)

Glen, C., Morrow, A., Roditi, G., Hopkins, T., Macpherson, I., Stewart, P., Petrie, M. C., Berry, C., Epstein, F., Lang, N. N., Mangion, K. (2023) Cardiovascular sequalae of trastuzumab and anthracycline in long-term survivors of breast cancer. Heart, (doi: 10.1136/heartjnl-2023-323437)

Mayne, K. J. et al. (2023) Effects of empagliflozin on fluid overload, weight and blood pressure in chronic kidney disease. Journal of the American Society of Nephrology, (doi: 10.1681/ASN.0000000000000271)

Bagordo, D., Rossi, G. P., Delles, C., Wiig, H., Rossitto, G. (2023) The tangram of sodium and fluid balance: salt series. Hypertension, (doi: 10.1161/HYPERTENSIONAHA.123.19569)

Neupane, D., Mukhtar, Q., Krajan Pardo, E. K., Acharya, S. D., Delles, C., Sharman, J. E., Cobb, L., Lackland, D. T., Moran, A., Weber, M. A., Olsen, M. H. (2023) Emerging Authors Program for building cardiovascular disease prevention and management research capacity in low- and middle-income countries: a collaboration of the U.S. Centers for Disease Control and Prevention, the Lancet Commission on Hypertension Group, Resolve to Save Lives, and the World Hypertension League. Journal of Human Hypertension, pp. -023. (doi: 10.1038/s41371-023-00880-4)

Welsh, S. A., Hussey, K., Brittenden, J., Orr, D. J., Quinn, T. (2023) Frailty Assessment in Vascular OUtpatients Review (FAVOUR) PROTOCOL – single-centre prospective cohort study comparing feasibility and prognostic value of commonly used frailty assessment tools. BMJ Open, 13, (doi: 10.1136/bmjopen-2023-079387)

Welsh, P., Kimenai, D. M., Shah, A. S.V., Gadd, D. A., Marioni, R. E., Woodward, M., Sudlow, C. L.M., Campbell, A., Cleland, J. G.F., Pellicori, P., Hayward, C., Mills, N. L., Sattar, N. (2023) Multiple cardiac biomarkers to improve prediction of cardiovascular events: findings from the Generation Scotland Scottish Family Health Study. Clinical Chemistry, 70, pp. 403-413. (doi: 10.1093/clinchem/hvad205)

Connelly, P., Osmanska, J., Lee, M. M.Y., Delles, C., McEntegart, M. B., Byrne, J. (2023) A case report of myocardial infarction in a young transgender man with testosterone therapy? raising awareness on healthcare issues in the transgender community and a call for further research. European Heart Journal: Case Reports, 7, (doi: 10.1093/ehjcr/ytad562)

Andonovic, M., Curle, J., Traynor, J. P., Shaw, M., Sim, M. A.B., Mark, P. B., Puxty, K. A. (2023) Impact of acute kidney injury on major adverse cardiovascular events in intensive care survivors. BJA Open, 8, (doi: 10.1016/j.bjao.2023.100243)

Berry, C. et al. (2023) Mental health symptoms and illness trajectory following COVID-19 hospitalization: A cohort study. Heart and Mind, 7, pp. 235-245. (doi: 10.4103/hm.HM-D-23-00037)

Pellicori, P., Cleland, J. G.F., Borentain, M., Taubel, J., Graham, F., Khan, J., Bruzzese, D., Kessler, P., McMurray, J. J.V., Voors, A. A., O’Connor, C. M., Teerlink, J. R., Felker, G. M. (2023) Impact of vasodilators on diuretic response in patients with congestive heart failure: a mechanistic trial of cimlanod (BMS‐986231) European Journal of Heart Failure, (doi: 10.1002/ejhf.3077)

Henriksen, P. A. et al. (2023) Multicenter, prospective, randomized controlled trial of high-sensitivity cardiac troponin I–guided combination angiotensin receptor blockade and beta-blocker therapy to prevent anthracycline cardiotoxicity: The Cardiac CARE trial. Circulation, 148, pp. 1680-1690. (doi: 10.1161/CIRCULATIONAHA.123.064274)

Desson, Z., Sharman, J. E., Searles, A., Schutte, A. E., Delles, C., Olsen, M. H., Ordunez, P., Hure, A., Morton, R., Figtree, G., Webster, J., Jennings, G., Redfern, J., Nicolls, S., McNamara, M., Deeming, S., Doyle, K., Ramanathan, S. (2023) Improving the accuracy of blood pressure measuring devices in Australia: a modelled return on investment study. Journal of Human Hypertension, (doi: 10.1038/s41371-023-00866-2)

McDowell, K., Adamson, C., Jackson, C., Campbell, R., Welsh, P., Petrie, M. C., McMurray, J. J.V., Jhund, P., Herring, N. (2023) Neuropeptide Y is elevated in heart failure and is an independent predictor of outcomes. European Journal of Heart Failure, (doi: 10.1002/ejhf.3085)

Ray, R., Ford, I., Cleland, J. G.F., Graham, F., Ahmed, F. Z., Al-Mohammad, A., Cowburn, P. J., Critoph, C., Kalra, P. A., Lane, R. E., Ludman, A., Pellicori, P., Petrie, M. C., Robertson, M., Seed, A., Squire, I., Kalra, P. R. (2023) The impact of ferric derisomaltose on cardiovascular and non-cardiovascular events in patients with anemia, iron deficiency and heart failure with reduced ejection fraction. Journal of Cardiac Failure, (doi: 10.1016/j.cardfail.2023.10.006)

Murphy, C. N., Delles, C., Davies, E., Connelly, P. J. (2023) Cardiovascular disease in transgender individuals. Atherosclerosis, 384, (doi: 10.1016/j.atherosclerosis.2023.117282)

Purcell, C., Purvis, A., Cleland, J. G.F., Cowie, A., Dalal, H. M., Ibbotson, T., Murphy, C., Taylor, R. S. (2023) Home-based cardiac rehabilitation for people with heart failure and their caregivers: a mixed-methods analysis of the roll out an evidence-based programme in Scotland (SCOT:REACH-HF study) European Journal of Cardiovascular Nursing, 22, pp. 804-813. (doi: 10.1093/eurjcn/zvad004)

Sattar, N., Taheri, S., Astling, D. P., Chadwick, J., Hinterberg, M. A., Holmes, M. V., Troth, E. V., Welsh, P., Zaghloul, H., Chagoury, O., Lean, M., Taylor, R., Williams, S. (2023) Prediction of cardiometabolic health through changes in plasma proteins with intentional weight loss in the DiRECT and DIADEM-I randomised clinical trials of type 2 diabetes remission. Diabetes Care, 46, pp. 1949-1957. (doi: 10.2337/dc23-0602)

Martin, T. P., MacDonald, E. A., Bradley, A., Watson, H., Saxena, P., Rog-Zielinska, E. A., Raheem, A., Fisher, S., Elbassioni, A. A. M., Almuzaini, O., Booth, C., Campbell, M., Riddell, A., Herzyk, P., Blyth, K., Nixon, C., Zentilin, L., Berry, C., Braun, T., Giacca, M., McBride, M. W., Nicklin, S. R., Cameron, E. R., Loughrey, C. (2023) Ribonucleicacid interference or small molecule inhibition of Runx1 in the border zone prevents cardiac contractile dysfunction following myocardial infarction. Cardiovascular Research, 119, pp. 2663–2671-2663–2671. (doi: 10.1093/cvr/cvad107)

Sze, S., Pellicori, P., Zhang, J., Weston, J., Clark, A. L. (2023) Which frailty tool best predicts morbidity and mortality in ambulatory patients with heart failure? A prospective study. European Heart Journal: Quality of Care and Clinical Outcomes, 9, pp. 731-739. (doi: 10.1093/ehjqcco/qcac073)

Jani, B. D., Sullivan, M. K., Hanlon, P., Nicholl, B. I., Lees, J. S., Brown, L., MacDonald, S., Mark, P. B., Mair, F. S., Sullivan, F. M. (2023) Personalised lung cancer risk stratification and lung cancer screening: do general practice electronic medical records have a role? British Journal of Cancer, (doi: 10.1038/s41416-023-02467-9)

Glen, C., Adam, S., McDowell, K., Waterston, A., Tan, Y. Y., Petrie, M. C., Coats, C. J., Lang, N. N. (2023) Cardiotoxicity of BRAF/MEK inhibitors: a longitudinal study incorporating contemporary definitions and risk scores. JACC: CardioOncology, 5, pp. 628-637. (doi: 10.1016/j.jaccao.2023.04.004)

McDonagh, T. A. et al. (2023) 2023 Focused Update of the 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: developed by the task force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC) with the special contribution of the Heart Failure Association (HFA) of the ESC. European Heart Journal, 44, pp. 3627-3639. (doi: 10.1093/eurheartj/ehad195)

Boonpor, J., Parra-Soto, S., Talebi, A., Zhou, Z., Carrasco-Marín, F., Petermann-Rocha, F., Welsh, P., Pell, J. P., Sattar, N., Gill, J. M.R., Gray, S. R., Celis-Morales, C., Ho, F. K. (2023) Associations and predictive performance of eleven anthropometric measures with incident type 2 diabetes: a prospective cohort study from the UK Biobank. Obesity, 31, pp. 2648-2657. (doi: 10.1002/oby.23849)

Giommi, A., Gurgel, A. R. B., Smith, G. L., Workman, A. J. (2023) Does the small conductance Ca2+-activated K+ current ISK flow under physiological conditions in rabbit and human atrial isolated cardiomyocytes? Journal of Molecular and Cellular Cardiology, 183, pp. 70-80. (doi: 10.1016/j.yjmcc.2023.09.002)

Lees, J. S., Mark, P. B. (2023) GFR slope as a surrogate marker for future kidney failure. Nature Reviews Nephrology, 19, pp. 625-626. (doi: 10.1038/s41581-023-00748-3)

Cuthbert, J. J., Cleland, J. G.F. (2023) Should we resurrect acetazolamide as a diuretic for congestion due to heart failure? Cardiovascular Research, 119, pp. e149-e151. (doi: 10.1093/cvr/cvad148)

Wei, L., Phillippo, D. M., Shah, A., Cleland, J. G.F., Lewsey, J., McAllister, D. A. (2023) Transportability of two heart failure trials to a disease registry using individual patient data. Journal of Clinical Epidemiology, 162, pp. 160-168. (doi: 10.1016/j.jclinepi.2023.08.019)

Del Vecchio, L., Balafa, O., Dounousi, E., Ekart, R., Fernandez Fernandez, B., Mark, P. B., Sarafidis, P., Valdivielso, J. M., Ferro, C. J., Mallamaci, F. (2023) COVID-19 and cardiovascular disease: Additional risks for patients with chronic kidney disease. Nephrology Dialysis Transplantation, (doi: 10.1093/ndt/gfad170)

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Leo, V. C., Kazmi, S., Brownrigg, J., Araghi, M., Sarna, H. S., Pellicori, P., Cuthbert, J., Cleland, J. G.F., Clark, A. L. (2023) Estimating nuclear scanning capacity requirements for patients with suspected cardiac transthyretin amyloidosis. ESC Heart Failure, 10, pp. 1492-1496. (doi: 10.1002/ehf2.14315)

Graham, F. J., Pellicori, P., Kalra, P. R., Ford, I., Bruzzese, D., Cleland, J. G.F. (2023) Intravenous iron in patients with heart failure and iron deficiency: an updated meta-analysis. European Journal of Heart Failure, 25, pp. 528-537. (doi: 10.1002/ejhf.2810)

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Ferreira, J. P., Cleland, J. G.F., Girerd, N., Pellicori, P., Hazebroek, M. R., Verdonschot, J., Collier, T. J., Retutschnigg, J., Clark, A. L., Staessen, J. A., Heymans, S., Rossignol, P., Zannad, F. (2023) Effect of spironolactone on QRS duration in patients at risk for heart failure (from the HOMAGE trial) American Journal of Cardiology, 191, pp. 39-42. (doi: 10.1016/j.amjcard.2022.12.016)

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Cohen, J. B., Brown, N. J., Brown, S.-A., Dent, S., van Dorst, D. C.H., Herrmann, S. M., Lang, N. N., Oudit, G. Y., Touyz, R. M. (2023) Cancer therapy–related hypertension: a scientific statement from the American Heart Association. Hypertension, 80, pp. e46-e57. (doi: 10.1161/HYP.0000000000000224)

Mayne, K. J., Lees, J. S., Mark, P. B. (2023) Cardiovascular complications of chronic kidney disease. Medicine, 51, pp. 190-195. (doi: 10.1016/j.mpmed.2022.12.008)

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Adamson, C., Welsh, P., Docherty, K. F., de Boer, R. A., Diez, M., Drożdż, J., Dukát, A., Inzucchi, S. E., Køber, L., Kosiborod, M. N., Ljungman, C. E.A., Martinez, F. A., Ponikowski, P., Sabatine, M. S., Morrow, D. A., Lindholm, D., Hammarstedt, A., Boulton, D. W., Greasley, P. J., Langkilde, A. M., Solomon, S. D., Sattar, N., McMurray, J. J.V., Jhund, P. S. (2023) IGFBP-7 and outcomes in heart failure with reduced ejection fraction: findings from DAPA-HF. JACC: Heart Failure, 11, pp. 291-304. (doi: 10.1016/j.jchf.2022.09.004)

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Picone, D. S., Peterson, G. M., Jackson, S. L., Campbell, N. R.C., Delles, C., Olsen, M. H., Padwal, R., Schutte, A. E., Sharman, J. E. (2023) Perceptions of pharmacists on the quality of automated blood pressure devices: a national survey. Journal of Human Hypertension, 37, pp. 235-240. (doi: 10.1038/s41371-022-00670-4)

Kobashigawa, J. A., FellstrÖm, B., Mark, P. B., Jardine, A. G. (2023) Special patient populations: transplant recipients. Elsevier

Mark, P. B., Jardine, A. G., Patel, R. K. (2023) Special populations: chronic kidney disease. Elsevier

Chen, D. C., Lees, J. S., Lu, K., Scherzer, R., Rutherford, E., Mark, P. B., Kanaya, A. M., Shlipak, M. G., Estrella, M. M. (2023) Differential associations of cystatin C versus creatinine‐based kidney function with risks of cardiovascular event and mortality among South Asian individuals in the UK Biobank. Journal of the American Heart Association, 12, (doi: 10.1161/JAHA.122.027079)

Gladysheva, I. P., Sullivan, R. D., Pellicori, P. (2023) Editorial: Edema in heart failure with reduced ejection fraction. Frontiers in Cardiovascular Medicine, 10, (doi: 10.3389/fcvm.2023.1141937)

Boorsma, E. M., ter Maaten, J. M., Damman, K., van Essen, B. J., Zannad, F., van Veldhuisen, D. J., Samani, N. J., Dickstein, K., Metra, M., Filippatos, G., Lang, C. C., Ng, L., Anker, S. D., Cleland, J. G., Pellicori, P., Gansevoort, R.T., Heerspink, H. J.L., Voors, A. A., Emmens, J. E. (2023) Albuminuria as a marker of systemic congestion in patients with heart failure. European Heart Journal, 44, pp. 368-380. (doi: 10.1093/eurheartj/ehac528)

de Beer, D., Mels, C. M. C., Schutte, A. E., Delles, C., Mary, S., Mullen, W., Mischak, H., Kruger, R. (2023) A urinary peptidomics approach for early stages of cardiovascular disease risk: the African-PREDICT study. Hypertension Research, 46, pp. 485-494. (doi: 10.1038/s41440-022-01097-7)

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Whinnett, Z. I. et al. (2023) Effects of haemodynamically atrio‐ventricular optimized His‐pacing on heart failure symptoms and exercise capacity: the His Optimized Pacing Evaluated for Heart Failure (HOPE‐HF) randomised, double‐blind, cross‐over trial. European Journal of Heart Failure, 25, pp. 274-283. (doi: 10.1002/ejhf.2736)

Docherty, K. F., McMurray, J. J.V., Claggett, B. L., Miao, Z. M., Adams, K. F., Arias‐Mendoza, A., Cleland, J. G.F., Diaz, R., Echeverría Correa, L. E., Felker, G. M., Fonseca, C., Li, J., Metra, M., Sliwa‐Hahnle, K., Solomon, S. D., Vandekerckhove, H. J., Vinereanu, D., Voors, A. A., Heitner, S. B., Kupfer, S., Malik, F. I., Meng, L., Teerlink, J. R. (2023) Efficacy of omecamtiv mecarbil in heart failure with reduced ejection fraction according to N‐terminal pro‐B ‐type natriuretic peptide level: insights from the GALACTIC‐HF trial. European Journal of Heart Failure, 25, pp. 248-259. (doi: 10.1002/ejhf.2763)

Chu, W., Lynskey, N., Iain-Ross, J., Pell, J. P., Sattar, N., Ho, F. K., Welsh, P., Celis-Morales, C., Petermann-Rocha, F. (2023) Identifying the biomarker profile of pre-frail and frail people: a cross-sectional analysis from UK Biobank. International Journal of Environmental Research and Public Health, 20, (doi: 10.3390/ijerph20032421)

Lim, M. W.S., Setjiadi, D., Dobbin, S. J.H., Lang, N. N., Delles, C., Connelly, P. J. (2023) Nailfold video-capillaroscopy in the study of cardiovascular disease: a systematic review. Blood Pressure Monitoring, 28, pp. 24-32. (doi: 10.1097/MBP.0000000000000624)

Rushworth, L. K., Loveridge, C., Salji, M., MacLeod, M., Mui, E., Sumpton, D., Neilson, M., Hedley, A., Alexander, L., McCartney, E., Patel, R., Wallace, J., Delles, C., Jones, R., Leung, H. Y. (2023) Phase II proof of concept study of atorvastatin in castration resistant prostate cancer. BJU International, 131, pp. 236-243. (doi: 10.1111/bju.15851)

Sullivan, M. K., Jani, B. D., Rutherford, E., Welsh, P., McConnachie, A., Major, R. W., McAllister, D., Nitsch, D., Mair, F. S., Mark, P. B., Lees, J. S. (2023) Potential impact of NICE guidelines on referrals from primary care to nephrology: a primary care database and prospective research study. British Journal of General Practice, 73, pp. e141-e147. (doi: 10.3399/BJGP.2022.0145)

Chen, J. Y., Chew, K. S., Mary, S., Boder, P., Bagordo, D., Rossi, G. P., Touyz, R. M., Delles, C., Rossitto, G. (2023) Skin-specific mechanisms of body fluid regulation in hypertension. Clinical Science, 137, pp. 239-250. (doi: 10.1042/CS20220609)

Sharman, J. E., Ordunez, P., Brady, T., Parati, G., Stergiou, G., Whelton, P. K., Padwal, R., Olsen, M. H., Delles, C., Schutte, A. E., Tomaszewski, M., Lackland, D. T., Khan, N., McManus, R. J., Tsuyuki, R. T., Zhang, X.-H., Murphy, L. D., Moran, A. E., Schlaich, M. P., Campbell, N. R.C. (2023) The urgency to regulate validation of automated blood pressure measuring devices: a policy statement and call to action from the world hypertension league. Journal of Human Hypertension, 37, pp. 155-159. (doi: 10.1038/s41371-022-00747-0)

Sykes, R. et al. (2023) Rationale and design of the effect of mineralocorticoid receptor antagonist therapy in patients with acute myocardial infarction or injury and non-obstructive coronary arteries: A registry-based, stratified-medicine, randomised, controlled trial. (doi: 10.1136/heartjnl-2022-BSCMR.26)

Sattar, N., Deanfield, J., Delles, C. (2023) Impact of intentional weight loss in cardiometabolic disease: what we know about timing of benefits on differing outcomes? Cardiovascular Research, (doi: 10.1093/cvr/cvac186)

Savarese, G., von Haehling, S., Butler, J., Cleland, J. G.F., Ponikowski, P., Anker, S. D. (2023) Iron deficiency and cardiovascular disease. European Heart Journal, 44, pp. 14-27. (doi: 10.1093/eurheartj/ehac569)

Sykes, R. et al. (2023) Adjudicated myocarditis and multisystem illness trajectory in healthcare workers post-COVID-19. Open Heart, 10, (doi: 10.1136/openhrt-2022-002192)

Ouwerkerk, W., Tromp, J., Cleland, J. G.F., Angermann, C. E., Dahlstrom, U., Ertl, G., Hassanein, M., Perrone, S. V., Ghadanfar, M., Schweizer, A., Obergfell, A., Dickstein, K., Filippatos, G., Collins, S. P., Lam, C. S. (2023) Association of time‐to‐IV ‐furosemide with mortality in acute heart failure: data from REPORT‐HF. European Journal of Heart Failure, 25, pp. 43-51. (doi: 10.1002/ejhf.2708)

Petrie, M. C., Jhund, P. S., Connolly, E., Mark, P. B., MacDonald, M. R., Robertson, M., Anker, S. D., Bhandari, S., Farrington, K., Kalra, P. A., Wheeler, D. C., Tomson, C. R.V., Ford, I., McMurray, J. J.V., Macdougall, I. C. (2023) High-dose intravenous iron reduces myocardial infarction in patients on haemodialysis. Cardiovascular Research, 119, pp. 213-220. (doi: 10.1093/cvr/cvab317)

Inciardi, R., Pellicori, P., Chandra, A. (2023) Identification and quantification of congestion in heart failure: a work in progress. European Journal of Heart Failure, 25, pp. 61-62. (doi: 10.1002/ejhf.2751)

Thöni, S., Keller, F., Denicolò, S., Eder, S., Buchwinkler, L., Rosivall, L., Wiecek, A., Mark, P. B., Rossing, P., Heerspink, H. L., Mayer, G. (2023) International variability of renal and cardiovascular outcomes and mortality in patients with type 2 diabetes mellitus in Europe. Kidney and Blood Pressure Research, 48, pp. 165-174. (doi: 10.1159/000528438)

Manla, Y., Kuan, W., Clark, A. L., Cleland, J. G. F., Pellicori, P. (2023) Ketone bodies in acute heart failure: fuel for thought. Journal of Cardiac Failure, 29, pp. 42-44. (doi: 10.1016/j.cardfail.2022.11.002)

Ortiz, A., Ferro, C. J., Balada, O., Burnier, M., Ekart, R., Halimi, J.-M., Kreutz, R., Mark, P. B., Persu, A., Rossignol, P., Ruilope, L. M., Schmieder, R. E., Valdivielso, J. M., del Vecchio, L., Zoccali, C., Mallamaci, F., Sarafidis, P. (2023) Mineralocorticoid receptor antagonists for nephroprotection and cardioprotection in patients with diabetes mellitus and chronic kidney disease. Nephrology Dialysis Transplantation, 38, pp. 10-25. (doi: 10.1093/ndt/gfab167)

Ferreira, J. P., Cleland, J. G., Girerd, N., Bozec, E., Rossignol, P., Pellicori, P., Cosmi, F., Mariottoni, B., Solomon, S. D., Pitt, B., Pfeffer, M. A., Shah, A. M., Petutschnigg, J., Pieske, B., Edelmann, F., Zannad, F. (2023) Spironolactone effect on cardiac structure and function of patients with heart failure and preserved ejection fraction: a pooled analysis of three randomized trials. European Journal of Heart Failure, 25, pp. 108-113. (doi: 10.1002/ejhf.2726)

Bell, S., Campbell, J., Watters, C., O'Neil, M., Almond, A., Buck, K., Carr, E. J., Cousland, Z., Findlay, M., Joss, N., Metcalfe, W., Spalding, E., Methven, S., Mark, P. B. (2023) The impact of Omicron on outcomes following infection with SARS-CoV-2 in patients with kidney failure in Scotland. Clinical Kidney Journal, 16, pp. 197-200. (doi: 10.1093/ckj/sfac173)

Welsh, P., Sattar, N. (2023) To apoB or not to apoB: new arguments, but basis for widespread implementation remains elusive. Clinical Chemistry, 69, pp. 3-5. (doi: 10.1093/clinchem/hvac183)

Kulkarni, S., Glover, M., Kapil, V., Abrams, S. M. L., Partridge, S., McCormack, T., Sever, P., Delles, C., Wilkinson, I. B. (2023) Management of hypertensive crisis: British and Irish Hypertension Society position document. Journal of Human Hypertension, (doi: 10.1038/s41371-022-00776-9)

2022

Lithgow, H., Johnston, L., Ho, F. K., Celis-Morales, C., Cobley, J., Raastad, T., Hunter, A. M., Lees, J. S., Mark, P. B., Quinn, T. J., Gray, S. R. (2022) Protocol for a randomised controlled trial to investigate the effects of vitamin K2 on recovery from muscle-damaging resistance exercise in young and older adults—the TAKEOVER study. Trials, 23, (doi: 10.1186/s13063-022-06937-y)

Kalra, P. R., Cleland, J. G.F., Petrie, M. C., Thomson, E. A., Kalra, P. A., Squire, I. B., Ahmed, F. Z., Al-Mohammad, A., Cowburn, P. J., Foley, P. W.X., Graham, F. J., Japp, A. G., Lane, R. E., Lang, N. N., Ludman, A. J., Macdougall, I. C., Pellicori, P., Ray, R., Robertson, M., Seed, A., Ford, I. (2022) Intravenous ferric derisomaltose in patients with heart failure and iron deficiency in the UK (IRONMAN): an investigator-initiated, prospective, randomised, open-label, blinded-endpoint trial. Lancet, 400, pp. 2199-2209. (doi: 10.1016/S0140-6736(22)02083-9)

Murray, E. C., Delles, C., Orzechowski, P., Renc, P., Sitek, A., Wagenaar, J., Guzik, T. J. (2022) Vascular phenotypes in early hypertension. Journal of Human Hypertension, (doi: 10.1038/s41371-022-00794-7)

McGettrick, M., Dormand, H., Brewis, M., Johnson, M. K., Lang, N. N., Church, A. C. (2022) Cardiac geometry, as assessed by cardiac magnetic resonance, can differentiate subtypes of chronic thromboembolic pulmonary vascular disease. Frontiers in Cardiovascular Medicine, 9, (doi: 10.3389/fcvm.2022.1004169)

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Lam, P. H., Keramida, K., Filippatos, G. S., Gupta, N., Faselis, C., Deedwania, P., George, B., Iskandrian, A., Cleland, J. G.F., Choudhary, G., Wu, W.-C., Morgan, C. J., Fonarow, G. C., Ahmed, A. (2022) Right ventricular ejection fraction and beta-blocker effect in heart failure with reduced ejection fraction: Beta-blocker and outcomes in HFrEF by RVEF. Journal of Cardiac Failure, 28, pp. 65-70. (doi: 10.1016/j.cardfail.2021.07.026)

Romaine, S. P. R., Denniff, M., Codd, V., Nath, M., Koekemoer, A., Anker, S. D., Cleland, J. G., Filippatos, G., Levin, D., Metra, M., Mordi, I. R., Ouwerkerk, W., ter Maaten, J. M., van Veldhuisen, D. J., Zannad, F., Ng, L. L., van der Harst, P., Lang, C. C., Voors, A. A., Nelson, C. P., Samani, N. J. (2022) Telomere length is independently associated with all-cause mortality in chronic heart failure. Heart, 108, pp. 124-129. (doi: 10.1136/heartjnl-2020-318654)

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2021

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Petermann-Rocha, F., Lyall, D. M., Gray, S. R., Gill, J. M.R., Sattar, N., Welsh, P., Quinn, T. J., Stewart, W., Pell, J. P., Ho, F. K., Celis-Morales, C. (2021) Dose-response association between device-measured physical activity and incident dementia: a prospective study from UK Biobank. BMC Medicine, 19, (doi: 10.1186/s12916-021-02172-5)

Crowe, K., Quinn, T. J., Mark, P. B., Findlay, M. D. (2021) “Is it removed during dialysis?”—cognitive dysfunction in advanced kidney failure—a review article. Frontiers in Neurology, 12, (doi: 10.3389/fneur.2021.787370)

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Meijers, W. C., Bayes‐Genis, A., Mebazaa, A., Bauersachs, J., Cleland, J. J.G., Coats, A. J.S., Januzzi, J. L., Maisel, A. S., McDonald, K., Mueller, T., Richards, A. M., Seferovic, P., Mueller, C., de Boer, R. A. (2021) Circulating heart failure biomarkers beyond natriuretic peptides: review from the Biomarker Study Group of the Heart Failure Association (HFA), European Society of Cardiology (ESC) European Journal of Heart Failure, 23, pp. 1610-1632. (doi: 10.1002/ejhf.2346)

Dalal, H., Taylor, R. S., Cleland, J. G. (2021) Correspondence to European Heart Journal—Quality of Care and Clinical Outcomes in response to paper by Thomas, M. et al. 2021: Predicting the EQ-5D from the Kansas City Cardiomyopathy Questionnaire (KCCQ) in patients with heart failures. European Heart Journal: Quality of Care and Clinical Outcomes, 7, pp. e7. (doi: 10.1093/ehjqcco/qcab033)

Jani, B. D., Nicholl, B. I., Hanlon, P., Mair, F. S., Gill, J. M.R., Gray, S. R., Celis-Morales, C. A., Ho, F. K., Lyall, D. M., Anderson, J. J., Hastie, C. E., Bailey, M. E.S., Foster, H., Pell, J. P., Welsh, P., Sattar, N. (2021) Family history of diabetes and risk of SARS-COV-2 in UK Biobank: a prospective cohort study. Endocrinology, Diabetes and Metabolism, 4, (doi: 10.1002/edm2.283)

Rankin, A. J., Zhu, L., Mangion, K., Rutherford, E., Gillis, K. A., Lees, J. S., Woodward, R., Patel, R. K., Berry, C., Roditi, G., Mark, P. B. (2021) Global longitudinal strain by feature tracking cardiovascular MRI predicts mortality in patients with end stage kidney disease. Clinical Kidney Journal, 14, pp. 2187-2196. (doi: 10.1093/ckj/sfab020)

Ferreira, J. P., Cleland, J. G., Lam, C. S.P., Anker, S. D., Mehra, M. R., van Veldhuisen, D. J., Byra, W. M., La Police, D. A., Pitt, B., Greenberg, B., Zannad, F. (2021) Heart failure re-hospitalizations and subsequent fatal events in coronary artery disease: insights from COMMANDER-HF, EPHESUS, and EXAMINE. Clinical Research in Cardiology, 110, pp. 1554-1563. (doi: 10.1007/s00392-021-01830-1)

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Pagnesi, M., Adamo, M., Sama, I. E., Anker, S. D., Cleland, J. G., Dickstein, K., Filippatos, G. S., Lang, C. C., Ng, L. L., Ponikowski, P., Ravera, A., Samani, N. J., Zannad, F., van Veldhuisen, D. J., Voors, A. A., Metra, M. (2021) Impact of mitral regurgitation in patients with worsening heart failure: insights from BIOSTAT-CHF. European Journal of Heart Failure, 23, pp. 1750-1758. (doi: 10.1002/ejhf.2276)

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Graham, F. J., Pellicori, P., Cleland, J. G.F., Clark, A. L. (2021) Reply to the letter regarding the article 'Natural history and prognostic significance of iron deficiency and anaemia in ambulatory patients with chronic heart failure' European Journal of Heart Failure, 23, pp. 1800-1801. (doi: 10.1002/ejhf.2304)

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Pellicori, P., Doolub, G., Wong, C. M., Lee, K. S., Mangion, K., Ahmad, M., Berry, C., Squire, I., Lambiase, P., Lyon, A. R., McConnachie, A., Taylor, R. S., Cleland, J. G.F. (2021) COVID-19 and its cardiovascular effects: a systematic review of prevalence studies. Cochrane Database of Systematic Reviews, 2021, (doi: 10.1002/14651858.CD013879)

Smart, N. A., Pearson, M. J., Taylor, R. S., Cleland, J. (2021) Exercise training for heart failure with preserved ejection fraction (ExTraMATCH III): protocol for an individual patient data meta-analysis. Journal of Clinical Exercise Physiology, 10, pp. 3-11. (doi: 10.31189/2165-7629-10.1.3)

Mordi, I. R., Ouwerkerk, W., Anker, S. D., Cleland, J. G., Dickstein, K., Metra, M., Ng, L. L., Samani, N. J., van Veldhuisen, D. J., Zannad, F., Voors, A. A., Lang, C. C. (2021) Heart failure treatment up-titration and outcome and age: an analysis of BIOSTAT-CHF. European Journal of Heart Failure, 23, pp. 436-444. (doi: 10.1002/ejhf.1799)

Ferreira, J. P., Cleland, J. G.F., Lam, C. S.P., van Veldhuisen, D., Byra, W. M., La Police, D. A., Anker, S. D., Mehra, M. R., Leroy, C., Eschwege, V., Toussaint-Hacquard, M., Rossignol, P., Greenberg, B., Zannad, F. (2021) Impact of geographic region on the COMMANDER-HF Trial. JACC: Heart Failure, 9, pp. 201-211. (doi: 10.1016/j.jchf.2020.11.007)

Crouch, S. H., Botha-Le Roux, S., Delles, C., Graham, L. A., Schutte, A. E. (2021) Inflammation and salt in young adults: the African-PREDICT study. European Journal of Nutrition, 60, pp. 873-882. (doi: 10.1007/s00394-020-02292-3)

Neves, K. B., Morris, H., Alves-Lopes, R., Muir, K. W., Moreton, F., Delles, C., Montezano, A. C., Touyz, R. M. (2021) Peripheral arteriopathy caused by Notch3 gain-of-function mutation involves ER and oxidative stress and blunting of NO∕sGC∕cGMP pathway. Clinical Science, 135, pp. 753-773. (doi: 10.1042/CS20201412)

Cameron, A. C., Neves, K. B., White, J., Touyz, R. M., Lang, N. N. (2021) Reply: Cisplatin-associated aortic thrombosis: a review of cases reported to the FDA adverse event reporting system. JACC: CardioOncology, 3, pp. 166. (doi: 10.1016/j.jaccao.2021.01.005)

Sze, S., Pellicori, P., Zhang, J., Weston, J., Clark, A. L. (2021) The impact of malnutrition on short-term morbidity and mortality in ambulatory patients with heart failure. American Journal of Clinical Nutrition, 113, pp. 695-705. (doi: 10.1093/ajcn/nqaa311)

Pearson, R., Asher, J., Jackson, A., Mark, P. B., Shumeyko, V., Clancy, M. J. (2021) Viability assessment and utilization of declined donor kidneys with rhabdomyolysis using ex vivo normothermic perfusion without preimplantation biopsy. American Journal of Transplantation, 21, pp. 1317-1321. (doi: 10.1111/ajt.16329)

Ehteshami-Afshar, S., Mooney, L., Dewan, P., Desai, A. S., Lang, N. N., Lefkowitz, M. P., Petrie, M. C., Rizkala, A. R., Rouleau, J. L., Solomon, S. D., Swedberg, K., Shi, V. C., Zile, M. R., Packer, M., McMurray, J. J.V., Jhund, P. S., Hawkins, N. M. (2021) Clinical characteristics and outcomes of patients with heart failure with reduced ejection fraction and chronic obstructive pulmonary disease: insights from PARADIGM-HF. Journal of the American Heart Association, 10, (doi: 10.1161/JAHA.120.019238)

Thom, G., McIntosh, A., Messow, C.-M., Leslie, W. S., Barnes, A. C., Brosnahan, N., McCombie, L., Malkova, D., Al-Mrabeh, A., Zhyzhneuskaya, S., Welsh, P., Sattar, N., Taylor, R., Lean, M. E.J. (2021) Weight loss induced increase in fasting ghrelin concentration is a predictor of weight regain: evidence from the Diabetes Remission Clinical Trial. Diabetes, Obesity and Metabolism, 23, pp. 711-719. (doi: 10.1111/dom.14274)

Lee, M. M.Y. et al. (2021) Effect of empagliflozin on left ventricular volumes in patients with type 2 diabetes, or prediabetes, and heart failure with reduced ejection fraction (SUGAR-DM-HF) Circulation, 143, pp. 516-525. (doi: 10.1161/CIRCULATIONAHA.120.052186)

Petrie, M. C., Lee, M. M., Lang, N. N. (2021) EMPEROR-REDUCED reigns while EMPERIAL whimpers. European Heart Journal, 42, pp. 711-714. (doi: 10.1093/eurheartj/ehaa965)

Cleland, J. G.F. et al. (2021) The effect of spironolactone on cardiovascular function and markers of fibrosis in people at increased risk of developing heart failure: the heart 'OMics' in AGEing (HOMAGE) randomized clinical trial. European Heart Journal, 42, pp. 684-696. (doi: 10.1093/eurheartj/ehaa758)

Rankin, A. J., Mark, P. B. (2021) Cardiac screening prior to renal transplantation – good intentions, rather than good evidence, dictate practice. Kidney International, 99, pp. 306-308. (doi: 10.1016/j.kint.2020.10.043)

Maznyczka, A. M., McCartney, P., Duklas, P., McEntegart, M., Oldroyd, K., Greenwood, J., Muir, D., Chowdhary, S., Gershlick, A. H., Eteiba, H., Cotton, J., Wragg, A., Curzen, N., Tait, R., Macfarlane, P., Welsh, P., Sattar, N., Petrie, M., Ford, I., Fox, K., McConnachie, A., Berry, C. (2021) Effect of coronary flow on intracoronary alteplase: a prespecified analysis from a randomised trial. Heart, 107, pp. 299-312. (doi: 10.1136/heartjnl-2020-317828)

Felker, G. M. et al. (2021) Effects of a novel nitroxyl donor in acute heart failure: the STAND-UP AHF Study. JACC: Heart Failure, 9, pp. 146-157. (doi: 10.1016/j.jchf.2020.10.012)

Donin, A. S., Nightingale, C. M., Perkin, M. R., Ussher, M., Jebb, S. A., Landberg, R., Welsh, P., Sattar, N., Adab, P., Owen, C. G., Rudnicka, A. R., Cook, D. G., Whincup, P. H. (2021) Evaluating an intervention to increase cereal fiber intake in children: a randomized controlled feasibility trial. Journal of Nutrition, 151, pp. 379-386. (doi: 10.1093/jn/nxaa347)

Halliday, B. P., Owen, R., Gregson, J., Vassiliou, V., Chen, X., Wage, R., Lota, A. S., Khalique, Z., Tayal, U., Hammersley, D. J., Jones, R. E., Baksi, A. J., Cowie, M. R., Cleland, J. G.F., Pennell, D. J., Prasad, S. K. (2021) Myocardial remodelling after withdrawing therapy for heart failure in patients with recovered dilated cardiomyopathy – insights from TRED‐HF. European Journal of Heart Failure, 23, pp. 293-301. (doi: 10.1002/ejhf.2063)

Docherty, K. F., Campbell, R. T., Brooksbank, K. J.M., Godeseth, R. L., Forsyth, P., McConnachie, A., Roditi, G., Stanley, B., Welsh, P., Jhund, P. S., Petrie, M. C., McMurray, J. J.V. (2021) Rationale and methods of a randomized trial evaluating the effect of neprilysin inhibition on left ventricular remodelling. ESC Heart Failure, 8, pp. 129-138. (doi: 10.1002/ehf2.13137)

Al Ozairi, E., Alroudhan, D., Alsaeed, D., Voase, N., Hasan, A., Gill, J. M.R., Sattar, N., Welsh, P., Gray, C. M., Boonpor, J., Celis-Morales, C., Gray, S. R. (2021) Skeletal muscle and metabolic health – how do we increase muscle mass and function in people with type 2 diabetes. Journal of Clinical Endocrinology and Metabolism, 106, pp. 309-317. (doi: 10.1210/clinem/dgaa835)

Andonovic, M., Shemilt, R., Sim, M., Traynor, J. P., Shaw, M., Mark, P. B., Puxty, K. A. (2021) Timing of renal replacement therapy for patients with acute kidney injury: a systematic review and meta-analysis. Journal of the Intensive Care Society, 22, pp. 67-77. (doi: 10.1177/1751143720901688)

Connelly, P. J., Clark, A., Touyz, R. M., Delles, C. (2021) Transgender adults, gender-affirming hormone therapy and blood pressure: a systematic review. Journal of Hypertension, 39, pp. 223-230. (doi: 10.1097/HJH.0000000000002632)

Samuel, N. A., Cuthbert, J. J., Brown, O. I., Kazmi, S., Cleland, J. G.F., Rigby, A. S., Clark, A. L. (2021) Relation between thyroid function and mortality in patients with chronic heart failure. American Journal of Cardiology, 139, pp. 57-63. (doi: 10.1016/j.amjcard.2020.10.034)

Teerlink, J. R. et al. (2021) Cardiac myosin activation with omecamtiv mecarbil in systolic heart failure. New England Journal of Medicine, 384, pp. 105-116. (doi: 10.1056/NEJMoa2025797)

Bekfani, T., Fudim, M., Cleland, J. G.F., Jorbenadze, A., Haehling, S., Lorber, A., Rothman, A. M.‐K., Stein, K., Abraham, W. T., Sievert, H., Anker, S. D. (2021) A current and future outlook on upcoming technologies in the remote monitoring of patients with heart failure. European Journal of Heart Failure, 23, pp. 175-185. (doi: 10.1002/ejhf.2033)

Rutherford, E., Ireland, S., Mangion, K., Stewart, G. A., MacGregor, M., Roditi, G., Woodward, R., Gandy, S. J., Houston, J. G., Jardine, A., Rauchhaus, P., Witham, M. D., Mark, P. D., Struthers, A. D. (2021) A randomized, controlled trial of the effect of allopurinol on left ventricular mass index in hemodialysis patients. Kidney International Reports, 6, pp. 146-155. (doi: 10.1016/j.ekir.2020.10.025)

Moreton, F. C., Cullen, B., Dickie, D. A., Lopez Gonzalez, R., Santosh, C., Delles, C., Muir, K. W. (2021) Brain imaging factors associated with progression of subcortical hyperintensities in CADASIL over two year follow up. European Journal of Neurology, 28, pp. 220-228. (doi: 10.1111/ene.14534)

Dobbin, S. J.H., Petrie, M. C., Myles, R. C., Touyz, R. M., Lang, N. N. (2021) Cardiotoxic effects of angiogenesis inhibitors. Clinical Science, 135, pp. 71-100. (doi: 10.1042/CS20200305)

Lees, J. S., Mark, P. B. (2021) Cystatin C to predict renal disease and cardiovascular risk. Nephrology Dialysis Transplantation, 36, pp. 39-41. (doi: 10.1093/ndt/gfaa152)

Davison, B. A., Senger, S., Sama, I. E., Koch, G. G., Mebazaa, A., Dickstein, K., Samani, N. J., Metra, M., Anker, S. D., Cleland, J. G., Ng, L. L., Mordi, I. R., Zannad, F., Filippatos, G. S., Hillege, H. L., Ponikowski, P., Veldhuisen, D. J., Lang, C. C., Meer, P., Núñez, J., Bayés‐Genís, A., Edwards, C., Voors, A. A., Cotter, G. (2021) Is acute heart failure a distinctive disorder? An analysis from BIOSTAT‐CHF. European Journal of Heart Failure, 23, pp. 43-57. (doi: 10.1002/ejhf.2077)

Mark, P. B., Del Vecchio, L., Valdivielso, J. M., Malyszko, J. (2021) Same rhythm, different song - approaches to atrial fibrillation management by cardiologists and nephrologists. Clinical Kidney Journal, 14, pp. 9-13. (doi: 10.1093/ckj/sfaa146)

He, T., Melgarejo, J. D., Clark, A. L., Yu, Y.‐L., Thijs, L., Díez, J., López, B., González, A., Cleland, J. G., Schanstra, J. P., Vlahou, A., Latosinska, A., Mischak, H., Staessen, J. A., Zhang, Z.‐Y., Jankowski, V. (2021) Serum and urinary biomarkers of collagen type‐I turnover predict prognosis in patients with heart failure. Clinical and Translational Medicine, 11, (doi: 10.1002/ctm2.267)

Dounousi, E., Tellis, C., Pavlakou, P., Duni, A., Liakopoulos, V., Mark, P. B., Papagianni, A., Tselepis, A. D. (2021) Association between PCSK9 levels and markers of inflammation, oxidative stress, and endothelial dysfunction in a population of nondialysis chronic kidney disease patients. Oxidative Medicine and Cellular Longevity, 2021, (doi: 10.1155/2021/6677012)

Anderson, J. J., Welsh, P., Ho, F. K., Ferguson, L. D., Welsh, C. E., Pellicori, P., Cleland, J. G.F., Forbes, J., Iliodromiti, S., Boyle, J., Lindsay, R., Celis-Morales, C., Gray, S. R., Katikireddi, S. V., Gill, J. M. R., Pell, J. P., Sattar, N. (2021) Ethnic differences in prevalence of actionable HbA1c levels in UK Biobank: implications for screening. BMJ Open Diabetes Research and Care, 9, (doi: 10.1136/bmjdrc-2021-002176)

Small, H. Y., Delles, C. (2021) Letter to the Editor regarding Cunningham et al. 2020. Hypertension in Pregnancy, 40, pp. 133. (doi: 10.1080/10641955.2021.1899201)

McGettrick, M., MacLellan, A., McCaughey, P., Bagot, C., Brewis, M.J., Lang, N.N., Johnson, M.K., Church, A.C. (2021) Pulmonary thromboembolism in hospitalised patients with COVID-19: a retrospective national study of patients managed in critical care and ward environments in Scotland. BMJ Open, 11, (doi: 10.1136/bmjopen-2021-050281)

Shoaib, A., Van Spall, H. G.C., Wu, J., Cleland, J. G.F., McDonagh, T. A., Rashid, M., Mohamed, M. O., Ahmed, F. Z., Deanfield, J., de Belder, M., Gale, C. P., Mamas, M. A. (2021) Substantial decline in hospital admissions for heart failure accompanied by increased community mortality during COVID-19 pandemic. European Heart Journal: Quality of Care and Clinical Outcomes, 7, pp. 378-387. (doi: 10.1093/ehjqcco/qcab040)

Shah, P., Pellicori, P., Hanning, I., Zhang, J., Clark, A. L., Bhandari, S. (2021) The effect of digoxin on renal function in patients with heart failure. BMC Nephrology, 22, (doi: 10.1186/s12882-021-02562-0)

Pearson, R., Murray, E., Thomson, P. C., Mark, P. B., Clancy, M. J., Asher, J. (2021) The new UK national kidney allocation scheme with maximized “R4-D4” kidney transplants: better patient-to-graft longevity matching may be at the cost of more resources. Experimental and Clinical Transplantation, 19, pp. 1133-1141. (doi: 10.6002/ect.2021.0129)

2020

Brown, R., Welsh, P., Logue, J. (2020) Systematic review of clinical guidelines for lipid-lowering in the secondary prevention of cardiovascular disease events. Open Heart, 7, (doi: 10.1136/openhrt-2020-001396)

Rossitto, G., Mary, S., McAllister, C., Neves, K. B., Haddow, L., Rocchiccioli, J. P., Lang, N. N., Murphy, C. L., Touyz, R. M., Petrie, M. C., Delles, C. (2020) Reduced lymphatic reserve in heart failure with preserved ejection fraction. Journal of the American College of Cardiology, 76, pp. 2817-2829. (doi: 10.1016/j.jacc.2020.10.022)

Goncalves Soares, A., Kilpi, F., Fraser, A., Nelson, S. M., Sattar, N., Welsh, P. I., Tilling, K., Lawlor, D. A. (2020) Longitudinal changes in reproductive hormones through the menopause transition in the Avon Longitudinal Study of Parents and Children (ALSPAC) Scientific Reports, 10, (doi: 10.1038/s41598-020-77871-9)

Purcell, C., Daw, P., Kerr, C., Cleland, J., Cowie, A., Dalal, H., Ibbotson, T., Murphy, C., Taylor, R. (2020) Protocol for an implementation study of an evidence-based home cardiac rehabilitation programme for people with heart failure and their caregivers in Scotland (SCOT:REACH-HF) BMJ Open, 10, (doi: 10.1136/bmjopen-2020-040771)

Mangion, K. et al. (2020) The Chief Scientist Office cardiovascular and pulmonary imaging in SARS Coronavirus disease-19 (CISCO-19) study. Cardiovascular Research, 116, pp. 2185-2196. (doi: 10.1093/cvr/cvaa209)

Ferguson, A. C., Tank, R., Lyall, L. M., Ward, J., Welsh, P., Celis-Morales, C., McQueenie, R., Strawbridge, R. J., Mackay, D. F., Pell, J. P., Smith, D. J., Sattar, N., Cavanagh, J., Lyall, D. M. (2020) Association of SBP and BMI with cognitive and structural brain phenotypes in UK Biobank. Journal of Hypertension, 38, pp. 2482-2489. (doi: 10.1097/HJH.0000000000002579)

Pellicori, P., Ofstad, A. P., Fitchett, D., Zeller, C., Wanner, C., George, J., Zinman, B., Brueckmann, M., Lindenfeld, J. (2020) Early benefits of empagliflozin in patients with or without heart failure: findings from EMPA-REG OUTCOME. ESC Heart Failure, 7, pp. 3401-3407. (doi: 10.1002/ehf2.12891)

Felker, G. M., Solomon, S. D., McMurray, J. J.V., Cleland, J. G.F., Abbasi, S. A., Malik, F. I., Zhang, H., Globe, G., Teerlink, J. R. (2020) Effects of omecamtiv mecarbil on symptoms and health-related quality of life in patients with chronic heart failure: results from the COSMIC-HF study. Circulation: Heart Failure, 13, (doi: 10.1161/CIRCHEARTFAILURE.120.007814)

Brown, O., Costanzo, P., Clark, A. L., Condorelli, G., Cleland, J. G.F., Sathyapalan, T., Hepburn, D., Kilpatrick, E. S., Atkin, S. L. (2020) Relationship between a single measurement at baseline of body mass index, glycated hemoglobin, and the risk of mortality and cardiovascular morbidity in type 2 diabetes mellitus. Cardiovascular Endocrinology and Metabolism, 9, pp. 177-182. (doi: 10.1097/XCE.0000000000000202)

Beazer, J. D., Patanapirunhakit, P., Gill, J. M.R., Graham, D., Karlsson, H., Ljunggren, S., Mulder, M., Freeman, D. J. (2020) High-density lipoprotein’s vascular protective functions in metabolic and cardiovascular disease - could extracellular vesicles be at play? Clinical Science, 134, pp. 2977-2986. (doi: 10.1042/CS20200892)

Ho, F. K., Celis-Morales, C. A., Gray, S. R., Katikireddi, S. V., Niedzwiedz, C. L., Hastie, C., Ferguson, L. D., Berry, C., Mackay, D. F., Gill, J. M.R., Pell, J. P., Sattar, N., Welsh, P. (2020) Modifiable and non-modifiable risk factors for COVID-19, and comparison to risk factors for influenza and pneumonia: results from a UK Biobank prospective cohort study. BMJ Open, 10, (doi: 10.1136/bmjopen-2020-040402)

Psotka, M. A. et al. (2020) Conduct of clinical trials in the era of COVID-19: JACC scientific expert panel. Journal of the American College of Cardiology, 76, pp. 2368-2378. (doi: 10.1016/j.jacc.2020.09.544)

Kerschbaum, J., Rudnicki, M., Dzien, A., Dzien-Bischinger, C., Winner, H., Heerspink, H. L., Rosivall, L., Wiecek, A., Mark, P. B., Eder, S., Denicolò, S., Mayer, G. (2020) Intra-individual variability of eGFR trajectories in early diabetic kidney disease and lack of performance of prognostic biomarkers. Scientific Reports, 10, (doi: 10.1038/s41598-020-76773-0)

Petermann-Rocha, F., Hanlon, P., Gray, S. R., Welsh, P., Gill, J. M.R., Foster, H., Katikireddi, S. V., Lyall, D., Mackay, D. F., O'Donnell, C., Sattar, N., Nicholl, B. I., Pell, J. P., Jani, B. D., Ho, F. K., Mair, F. S., Celis-Morales, C. (2020) Comparison of two different frailty measurements and risk of hospitalisation or death from COVID-19: findings from UK Biobank. BMC Medicine, 18, (doi: 10.1186/s12916-020-01822-4)

Ho, F. K., Petermann-Rocha, F., Gray, S. R., Jani, B. D., Katikireddi, S. V., Niedzwiedz, C. L., Foster, H., Hastie, C. E., Mackay, D. F., Gill, J. M.R., O'Donnell, C., Welsh, P., Mair, F., Sattar, N., Celis-Morales, C. A., Pell, J. P. (2020) Is older age associated with COVID-19 mortality in the absence of other risk factors? General population cohort study of 470,034 participants. PLoS ONE, 15, (doi: 10.1371/journal.pone.0241824)

McCartney, P. J. et al. (2020) Low-dose intracoronary alteplase during primary percutaneous coronary intervention in patients with acute myocardial infarction: the T-TIME three-arm RCT. Efficacy and Mechanism Evaluation, 7, (doi: 10.3310/eme07050)

Teerlink, J. R. et al. (2020) Omecamtiv mecarbil in chronic heart failure with reduced ejection fraction, GALACTIC‐HF: baseline characteristics and comparison with contemporary clinical trials. European Journal of Heart Failure, 22, pp. 2160-2171. (doi: 10.1002/ejhf.2015)

Morrow, A. J. et al. (2020) Rationale and design of the Medical Research Council precision medicine with Zibotentan in microvascular angina (PRIZE) trial. American Heart Journal, 229, pp. 70-80. (doi: 10.1016/j.ahj.2020.07.007)

Selvaraj, S., Claggett, B. L., Pfeffer, M. A., Desai, A. S., McCausland, F. R., McGrath, M. M., Anand, I. S., van van Veldhuisen, D. J., Kober, L., Janssens, S., Cleland, J. G.F., Pieske, B., Rouleau, J. L., Zile, M. R., Shi, V. C., Lefkowitz, M. P., McMurray, J. J.V., Solomon, S. D. (2020) Serum uric acid, influence of sacubitril/valsartan, and cardiovascular outcomes in heart failure with preserved ejection fraction: PARAGON-HF. European Journal of Heart Failure, 22, pp. 2093-2101. (doi: 10.1002/ejhf.1984)

Palazzuoli, A., Ruocco, G., Franci, B., Evangelista, I., Lucani, B., Nuti, R., Pellicori, P. (2020) Ultrasound indices of congestion in patients with acute heart failure according to body mass index. Clinical Research in Cardiology, 109, pp. 1423-1433. (doi: 10.1007/s00392-020-01642-9)

Foster, H. M.E., Ho, F. K., Sattar, N., Welsh, P., Pell, J. P., Gill, J. M.R., Gray, S. R., Celis-Morales, C. A. (2020) Understanding how much TV is too much: a non-linear analysis of the association between television viewing time and adverse health outcomes. Mayo Clinic Proceedings, 95, pp. 2429-2441. (doi: 10.1016/j.mayocp.2020.04.035)

Bell, S., Campbell, J., McDonald, J., O’Neill, M., Watters, C., Buck, K., Cousland, Z., Findlay, M., Lone, N. I., Metcalfe, W., Methven, S., Peel, R., Almond, A., Sanu, V., Spalding, E., Thomson, P. C., Mark, P. B., Traynor, J. P. (2020) COVID-19 in patients undergoing chronic kidney replacement therapy and kidney transplant recipients in Scotland: findings and experience from the Scottish renal registry. BMC Nephrology, 21, (doi: 10.1186/s12882-020-02061-8)

Wheeler, D. C. et al. (2020) The dapagliflozin and prevention of adverse outcomes in chronic kidney disease (DAPA-CKD) trial: baseline characteristics. Nephrology Dialysis Transplantation, 35, pp. 1700-1711. (doi: 10.1093/ndt/gfaa234)

Lang, N. N., Dobbin, S. J.H., Petrie, M. C. (2020) Vericiguat in worsening heart failure – agonising over, or celebrating, agonism. Cardiovascular Research, 116, pp. e152-e155. (doi: 10.1093/cvr/cvaa247)

Stoumpos, S., Tan, A., Hall Barrientos, P., Stevenson, K., Thomson, P., Kasthuri, R., Radjenovic, A., Kingsmore, D., Roditi, G., Mark, P. (2020) Ferumoxytol MR angiography vs Duplex ultrasound for vascular mapping before arteriovenous fistula surgery for hemodialysis. Radiology, 297, pp. 214-222. (doi: 10.1148/radiol.2020200069)

Rahimi, K., Nazarzadeh, M., Pinho-Gomes, A.-C., Woodward, M., Salimi-Khorshidi, G., Ohkuma, T., Fitzpatrick, R., Tarassenko, L., Denis, M., Cleland, J. (2020) Home monitoring with technology-supported management in chronic heart failure: a randomised trial. Heart, 106, pp. 1573-1578. (doi: 10.1136/heartjnl-2020-316773)

von Haehling, S., Garfias Macedo, T., Valentova, M., Anker, M. S., Ebner, N., Bekfani, T., Haarmann, H., Schefold, J. C., Lainscak, M., Cleland, J. G.F., Doehner, W., Hasenfuss, G., Anker, S. D. (2020) Muscle wasting as an independent predictor of survival in patients with chronic heart failure. Journal of Cachexia, Sarcopenia and Muscle, 11, pp. 1242-1249. (doi: 10.1002/jcsm.12603)

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Macdougall, I. C., Bhandari, S., White, C., Anker, S. D., Farrington, K., Kalra, P. A., Mark, P. B., McMurray, J. J.V., Reid, C., Robertson, M., Tomson, C. R.V., Wheeler, D. C., Winearls, C. G., Ford, I. (2020) Intravenous iron dosing and infection risk in patients on hemodialysis: a prespecified secondary analysis of the PIVOTAL trial. Journal of the American Society of Nephrology, 31, (doi: 10.1681/ASN.2019090972)

Rankin, A. J., Cannon, E., Gillis, K., Crosby, J., Mark, P. B., Geddes, C. C., Fox, J. G., Mackinnon, B., McQuarrie, E., Kipgen, D. (2020) Predicting outcome in acute interstitial nephritis: a case series examining the importance of histological parameters. Histopathology, 76, pp. 698-706. (doi: 10.1111/his.14031)

Wehner, G. J., Jing, L., Haggerty, C. M., Suever, J. D., Leader, J. B., Hartzel, D. N., Kirchner, H. L., Manus, J. N.A., James, N., Ayar, Z., Gladding, P., Good, C. W., Cleland, J. G.F., Fornwalt, B. K. (2020) Routinely reported ejection fraction and mortality in clinical practice: where does the nadir of risk lie? European Heart Journal, 41, pp. 1249-1257. (doi: 10.1093/eurheartj/ehz550)

Cleland, J. G.F., Lyon, A. R., McDonagh, T., McMurray, J. J.V. (2020) The year in cardiology: heart failure. European Heart Journal, 41, pp. 1232-1248. (doi: 10.1093/eurheartj/ehz949)

Welsh, C., Celis-Morales, C. A., Ho, F., Lyall, D. M., Mackay, D., Ferguson, L., Sattar, N., Gray, S. R., Gill, J. M.R., Pell, J. P., Welsh, P. (2020) Association of injury related hospital admissions with commuting by bicycle in the UK: prospective population based study. British Medical Journal, 368, (doi: 10.1136/bmj.m336)

Ho, F. K., Gray, S. R., Welsh, P., Petermann-Rocha, F., Foster, H., Waddell, H., Anderson, J., Lyall, D., Sattar, N., Gill, J. M.R., Mathers, J. C., Pell, J. P., Celis-Morales, C. (2020) Associations of fat and carbohydrate intake with cardiovascular disease and mortality: prospective cohort study of UK Biobank participants. British Medical Journal, 368, (doi: 10.1136/bmj.m688)

Tromp, J., Bamadhaj, S., Cleland, J. G.F., Angermann, C. E., Dahlstrom, U., Ouwerkerk, W., Tay, W. T., Dickstein, K., Ertl, G., Hassanein, M., Hu, D., Perrone, S. V., Ghadanfar, M., Schweizer, A., Obergfell, A., Lam, C. S.P., Filippatos, G., Collins, S. P. (2020) Post-discharge prognosis of patients admitted to hospital for heart failure by world region, and national level of income and income disparity (REPORT-HF): a cohort study. Lancet Global Health, 8, pp. e411-e422. (doi: 10.1016/S2214-109X(20)30004-8)

Santema, B. T., Chan, M. M.Y., Tromp, J., Dokter, M., van der Wal, H. H., Emmens, J. E., Takens, J., Samani, N. J., Ng, L. L., Lang, C. C., van der Meer, P., ter Maaten, J. M., Damman, K., Dickstein, K., Cleland, J. G., Zannad, F., Anker, S. D., Metra, M., van der Harst, P., de Boer, R. A., van Veldhuisen, D. J., Rienstra, M., Lam, C. S.P., Voors, A. A. (2020) The influence of atrial fibrillation on the levels of NT-proBNP versus GDF-15 in patients with heart failure. Clinical Research in Cardiology, 109, pp. 331-338. (doi: 10.1007/s00392-019-01513-y)

Rorth, R., Jhund, P. S., Yilmaz, M. B., Kristensen, S. L., Welsh, P., Desai, A. S., Køber, L., Prescott, M. F., Rouleau, J. L., Solomon, S. D., Swedberg, K., Zile, M. R., Packer, M., McMurray, J. J.V. (2020) Comparison of BNP and NT-proBNP in patients with heart failure and reduced ejection fraction. Circulation: Heart Failure, 13, (doi: 10.1161/CIRCHEARTFAILURE.119.006541)

Maznyczka, A. M., McCartney, P. J., Oldroyd, K. G., Lindsay, M., McEntegart, M., Eteiba, H., Rocchiccioli, P., Good, R., Shaukat, A., Robertson, K., Kodoth, V., Greenwood, J. P., Cotton, J. M., Hood, S., Watkins, S., Macfarlane, P. W., Kennedy, J., Tait, C., Welsh, P., Sattar, N., Collison, D., Gillespie, L., McConnachie, A., Berry, C. (2020) Effects of intracoronary alteplase on microvascular function in acute myocardial infarction. Journal of the American Heart Association, 9, (doi: 10.1161/JAHA.119.014066)

Cameron, A. C., Welsh, P., Neves, K. B., Newby, D., Touyz, R. M., Lang, N. (2020) Acute vascular effects of vascular endothelial growth factor inhibition in the forearm arterial circulation. Journal of Hypertension, 38, pp. 257-265. (doi: 10.1097/HJH.0000000000002230)

Rankin, A. J., Allwood-Spiers, S., Lee, M. M.Y., Zhu, L., Woodward, R., Kuehn, B., Radjenovic, A., Sattar, N., Roditi, G., Mark, P. B., Gillis, K. A. (2020) Comparing the interobserver reproducibility of different regions of interest on multi-parametric renal magnetic resonance imaging in healthy volunteers, patients with heart failure and renal transplant recipients. Magnetic Resonance Materials in Physics, Biology and Medicine, 33, pp. 103-112. (doi: 10.1007/s10334-019-00809-4)

Crouch, S. H., Botha-Le Roux, S., Delles, C., Graham, L. A., Schutte, A. E. (2020) Distinct inflammatory mediator patterns in young black and white adults: The African-PREDICT study. Cytokine, 126, (doi: 10.1016/j.cyto.2019.154894)

Bégué, C., Mörner, S., Brito, D., Hengstenberg, C., Cleland, J. G.F., Arbustini, E., Galve, E., Wichter, T., Richter, A., Golmard, J.-L., Bernard, M., Dubourg, O., Komajda, M., Charron, P., Isnard, R. (2020) Mid-regional proatrial natriuretic peptide for predicting prognosis in hypertrophic cardiomyopathy. Heart, 106, pp. 196-202. (doi: 10.1136/heartjnl-2019-314826)

Hockings, P., Laustsen, C., Joles, J., Mark, P., Sourbron, S. (2020) Special issue on magnetic resonance imaging biomarkers of renal disease. Magnetic Resonance Materials in Physics, Biology and Medicine, 33, pp. 1-2. (doi: 10.1007/s10334-019-00822-7)

Schlosser, K., Kaur, A., Dayan, N., Stewart, D. J., Pilote, L., Delles, C. (2020) Circulating miR-206 and Wnt-signaling are associated with cardiovascular complications and a history of preeclampsia in women. Clinical Science, 134, pp. 87-101. (doi: 10.1042/CS20190920)

Welsh, C., Welsh, P., Celis Morales, C. A., Mark, P., Mackay, D., Ghouri, N., Ho, F., Ferguson, L. D., Brown, R., Lewsey, J., Cleland, J. G., Gray, S. R., Lyall, D. M., Anderson, J., Jhund, P. S., Pell, J., McGuire, D. K., Gill, J. M.R., Sattar, N. (2020) Glycated hemoglobin, prediabetes and the links to cardiovascular disease: data from UK Biobank. Diabetes Care, 43, pp. 440-445. (doi: 10.2337/dc19-1683)

Filippatos, G., Angermann, C. E., Cleland, J. G.F., Lam, C. S.P., Dahlström, U., Dickstein, K., Ertl, G., Hassanein, M., Hart, K. W., Lindsell, C. J., Perrone, S. V., Guerin, T., Ghadanfar, M., Schweizer, A., Obergfell, A., Collins, S. P. (2020) Global differences in characteristics, precipitants, and initial management of patients presenting with acute heart failure. JAMA Cardiology, 5, pp. 401-410. (doi: 10.1001/jamacardio.2019.5108)

Ferreira, J. P., Ouwerkerk, W., Tromp, J., Ng, L., Dickstein, K., Anker, S., Filippatos, G., Cleland, J. G., Metra, M., van Veldhuisen, D. J., Voors, A. A., Zannad, F. (2020) Cardiovascular and non‐cardiovascular death distinction: the utility of troponin beyond N‐terminal pro‐B‐type natriuretic peptide. Findings from the BIOSTAT‐CHF study. European Journal of Heart Failure, 22, pp. 81-89. (doi: 10.1002/ejhf.1654)

Pellicori, P., Cleland, J. G.F., Clark, A. L. (2020) Chronic obstructive pulmonary disease and heart failure: a breathless conspiracy. Heart Failure Clinics, 16, pp. 33-44. (doi: 10.1016/j.hfc.2019.08.003)

Nikolaidou, T., Samuel, N. A., Marincowitz, C., Fox, D. J., Cleland, J. G.F., Clark, A. L. (2020) Electrocardiographic characteristics in patients with heart failure and normal ejection fraction: a systematic review and meta‐analysis. Annals of Noninvasive Electrocardiology, 25, (doi: 10.1111/anec.12710)

Kobayashi, M., Voors, A. A., Girerd, N., Billotte, M., Anker, S. D., Cleland, J. G., Lang, C. C., Ng, L. L., van Veldhuisen, D. J., Dickstein, K., Metra, M., Duarte, K., Rossignol, P., Zannad, F., Ferreira, J. P. (2020) Heart failure etiologies and clinical factors precipitating for worsening heart failure: Findings from BIOSTAT-CHF. European Journal of Internal Medicine, 71, pp. 62-69. (doi: 10.1016/j.ejim.2019.10.017)

Pellicori, P., Zhang, J., Cuthbert, J., Urbinati, A., Shah, P., Kazmi, S., Clark, A. L., Cleland, J. G.F. (2020) High sensitivity C-reactive protein in chronic heart failure: patient characteristics, phenotypes, and mode of death. Cardiovascular Research, 116, pp. 91-100. (doi: 10.1093/cvr/cvz198)

Pellicori, P., Khan, M. J. I., Graham, F. J., Cleland, J. G.F. (2020) New perspectives and future directions in the treatment of heart failure. Heart Failure Reviews, 25, pp. 147-159. (doi: 10.1007/s10741-019-09829-7)

Cao, T. H., Jones, D. J.L., Voors, A. A., Quinn, P. A., Sandhu, J. K., Chan, D. C.S., Parry, H. M., Mohan, M., Mordi, I. R., Sama, I. E., Anker, S. D., Cleland, J. G., Dickstein, K., Filippatos, G., Hillege, H. L., Metra, M., Ponikowski, P., Samani, N. J., Van Veldhuisen, D. J., Zannad, F., Lang, C. C., Ng, L. L. (2020) Plasma proteomic approach in patients with heart failure: insights into pathogenesis of disease progression and potential novel treatment targets. European Journal of Heart Failure, 22, pp. 70-80. (doi: 10.1002/ejhf.1608)

Mark, P. B., Papworth, R., Ramparsad, N., Tomlinson, L. A., Sahwney, S., Black, C., McConnachie, A., McCowan, C. (2020) Risk factors associated with biochemically detected and hospitalised acute kidney injury in patients prescribed renin angiotensin system inhibitors. British Journal of Clinical Pharmacology, 86, pp. 121-131. (doi: 10.1111/bcp.14141)

Anker, M. S., Hülsmann, M., Cleland, J. G. (2020) What do patients with heart failure die from? A single assassin or a conspiracy? European Journal of Heart Failure, 22, pp. 26-28. (doi: 10.1002/ejhf.1689)

Mary, S., Currie, G., Schutte, A. E., Delles, C. (2020) Cardiovascular proteomics. Academic Press

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McCartney, P. J., Maznyczka, A. M., Eteiba, H., McEntegart, M., Oldroyd, K. G., Greenwood, J. P., Mareida, N., Schmitt, M., McCann, G. P., Fairbairn, T., McAlindon, E., Tait, C., Welsh, P., Sattar, N., Orchard, V., Corcoran, D., Ford, T. J., Radjenovic, A., Ford, I., McConnachie, A., Berry, C. (2020) Low-dose alteplase during primary percutaneous coronary intervention according to ischemic time. Journal of the American College of Cardiology, 75, pp. 1406-1421. (doi: 10.1016/j.jacc.2020.01.041)

2019

Kotecha, D., Gill, S. K., Flather, M. D., Holmes, J., Packer, M., Rosano, G., Böhm, M., McMurray, J. J.V., Wikstrand, J., Anker, S. D., van Veldhuisen, D. J., Manzano, L., von Lueder, T. G., Rigby, A. S., Andersson, B., Kjekshus, J., Wedel, H., Ruschitzka, F., Cleland, J. G.F., Damman, K., Redon, J., Coats, A. J.S. (2019) Impact of renal impairment on beta-blocker efficacy in patients with heart failure. Journal of the American College of Cardiology, 74, pp. 2893-2904. (doi: 10.1016/j.jacc.2019.09.059)

Neves, K. B., Harvey, A. P., Moreton, F., Montezano, A. C., Rios, F. J., Alves-Lopes, R., Nguyen Dinh Cat, A., Rocchiccioli, P., Delles, C., Joutel, A., Muir, K., Touyz, R. M. (2019) ER stress and Rho kinase activation underlie the vasculopathy of CADASIL. JCI Insight, 4, (doi: 10.1172/jci.insight.131344)

Mace-Brickman, T., Eddeen, A. B., Carrero, J.-J., Mark, P. B., Molnar, A. O., Lam, N. N., Zimmerman, D., Harel, Z., Sood, M. M. (2019) The risk of stroke and stroke type in patients with atrial fibrillation and chronic kidney disease. Canadian Journal of Kidney Health and Disease, 6, pp. 1-9. (doi: 10.1177/2054358119892372)

Ferguson, L. D., Brown, R., Celis-Morales, C., Welsh, P., Lyall, D. M., Pell, J. P., McInnes, I. B., Siebert, S., Sattar, N. (2019) Association of central adiposity with psoriasis, psoriatic arthritis and rheumatoid arthritis: a cross-sectional study of the UK Biobank. Rheumatology, 58, pp. 2137-2142. (doi: 10.1093/rheumatology/kez192)

Connelly, P. J., Freel, E. M., Perry, C., Ewan, J., Touyz, R. M., Currie, G., Delles, C. (2019) Gender-affirming hormone therapy, vascular health and cardiovascular disease in transgender adults. Hypertension, 74, pp. 1266-1274. (doi: 10.1161/HYPERTENSIONAHA.119.13080)

Eastwood, S. V., Chaturvedi, N., Sattar, N., Welsh, P. I., Hughes, A. D., Tillin, T. (2019) Impact of kidney function on cardiovascular risk and mortality: a comparison of South Asian and European cohorts. American Journal of Nephrology, 50, pp. 425-433. (doi: 10.1159/000503873)

Kammer, M., Heinzel, A., Willency, J., Duffin, K., Mayer, G., Simons, K., Gerl, M., Klose, C., Heinze, G., Reindl-Schwaighofer, R., Hu, K., Perco, P., Eder, S., Rosivall, L., Mark, P., Ju, W., Kretzler, M., McCarthy, M., Heerspink, H. J., Wiecek, A., Gomez, M., Oberbauer, R. (2019) Integrative analysis of prognostic biomarkers derived from multiomics panels for the discrimination of chronic kidney disease trajectories in people with type 2 diabetes. Kidney International, 96, pp. 1381-1388. (doi: 10.1016/j.kint.2019.07.025)

Williams, E. H. et al. (2019) Multicentre validation of the CamGFR model for estimated glomerular filtration rate. JNCI Cancer Spectrum, 3, (doi: 10.1093/jncics/pkz068)

Johnson, M. J., Cockayne, S., Currow, D. C., Bell, K., Hicks, K., Fairhurst, C., Gabe, R., Torgerson, D., Jefferson, L., Oxberry, S., Ghosh, J., Hogg, K. J., Murphy, J., Allgar, V., Cleland, J. G.F., Clark, A. L. (2019) Oral modified release morphine for breathlessness in chronic heart failure: a randomised placebo-controlled trial. ESC Heart Failure, 6, pp. 1149-1160. (doi: 10.1002/ehf2.12498)

Cameron, A. C., Lang, N. N., Dominiczak, A. F., Jennings, G. L.R., Batlle, D., Bursztyn, M., Chugh, A. R., Floras, J. S., Taler, S. J., Touyz, R. M., Delles, C. (2019) Progressive hypertension and severe left ventricular outflow tract obstruction. Hypertension, 74, pp. 1216-1225. (doi: 10.1161/hypertensionaha.119.13343)

Mehra, M. R., Vaduganathan, M., Fu, M., Ferreira, J. P., Anker, S. A., Cleland, J. G.F., Lam, C. S.P., van Veldhuisen, D. J., Byra, W. M., Spiro, T., Deng, H., Zannad, F., Greenberg, B. (2019) A comprehensive analysis of the effects of rivaroxaban on stroke or transient ischaemic attack in patients with heart failure, coronary artery disease, and sinus rhythm: the COMMANDER HF trial. European Heart Journal, 40, pp. 3593-3602. (doi: 10.1093/eurheartj/ehz427)

Tillin, T., Tuson, C., Sowa, B., Chattopadhyay, K., Sattar, N., Welsh, P., Roberts, I., Ebrahim, S., Kinra, S., Hughes, A., Chaturvedi, N. (2019) Yoga and Cardiovascular Health Trial (YACHT): a UK-based randomised mechanistic study of a yoga intervention plus usual care versus usual care alone following an acute coronary event. BMJ Open, 9, (doi: 10.1136/bmjopen-2019-030119)

Sillars, A., Celis-Morales, C. A., Ho, F., Petermann, F., Welsh, P., Iliodromiti, S., Ferguson, L. D., Lyall, D. M., Anderson, J., Mackay, D., Pellicori, P., Cleland, J., Pell, J. P., Gill, J. M.R., Gray, S. R., Sattar, N. (2019) Association of fitness and grip-strength with heart failure: findings from the UK Biobank population-based study. Mayo Clinic Proceedings, 94, pp. 2230-2240. (doi: 10.1016/j.mayocp.2019.04.041)

Steell, L., Ho, F. K., Sillars, A., Petermann, F., Li, H., Lyall, D. M., Iliodromiti, S., Welsh, P., Anderson, J., Mackay, D. F., Pell, J. P., Sattar, N., Gill, J. M.R., Gray, S. R., Celis-Morales, C. A. (2019) Dose-response associations of cardiorespiratory fitness with all-cause mortality and incidence and mortality of cancer and cardiovascular and respiratory diseases: the UK Biobank cohort study. British Journal of Sports Medicine, 53, pp. 1371-1378. (doi: 10.1136/bjsports-2018-099093)

Ferguson, L., Welsh, P., Brown, R., Tindell, A., Kerrigan, S., Sattar, N., McInnes, I., Siebert, S. (2019) Effect of Phosphodiesterase 4 Inhibition with Apremilast on Cardiometabolic Outcomes in Psoriatic Arthritis – Initial Results from the Immune Metabolic Associations in Psoriatic Arthritis (IMAPA) Study.

Lees, J. S., Welsh, C. E., Celis-Morales, C. A., Mackay, D., Lewsey, J., Gray, S. R., Lyall, D. M., Cleland, J. G., Gill, J. M.R., Jhund, P. S., Pell, J., Sattar, N., Welsh, P., Mark, P. B. (2019) Glomerular filtration rate by differing measures, albuminuria and prediction of cardiovascular disease, mortality and end-stage kidney disease. Nature Medicine, 25, pp. 1753-1760. (doi: 10.1038/s41591-019-0627-8)

Beusekamp, J. C., Tromp, J., Cleland, J. G.F., Givertz, M. M., Metra, M., O’Connor, C. M., Teerlink, J. R., Ponikowski, P., Ouwerkerk, W., van Veldhuisen, D. J., Voors, A. A., van der Meer, P. (2019) Hyperkalemia and treatment with RAAS inhibitors during acute heart failure hospitalizations and their association with mortality. JACC: Heart Failure, 7, pp. 970-979. (doi: 10.1016/j.jchf.2019.07.010)

Pellicori, P., Urbinati, A., Kaur, K., Zhang, J., Shah, P., Kazmi, S., Capucci, A., Cleland, J. G.F., Clark, A. L. (2019) Prevalence and incidence of atrial fibrillation in ambulatory patients with heart failure. American Journal of Cardiology, 124, pp. 1554-1560. (doi: 10.1016/j.amjcard.2019.08.018)

Grant, C. H., Gillis, K. A., Lees, J. S., Traynor, J. P., Mark, P. B., Stevens, K. I. (2019) Proton pump inhibitor use and progression to major adverse renal events: a competing risk analysis. QJM: An International Journal of Medicine, 112, pp. 835-840. (doi: 10.1093/qjmed/hcz166)

Conrad, N., Judge, A., Canoy, D., Tran, J., Pinho-Gomes, A. C., Millett, E. R.C., Salimi-Khorshidi, G., Cleland, J. G., McMurray, J. J.V., Rahimi, K. (2019) Temporal trends and patterns in mortality after incident heart failure: a longitudinal analysis of 86 000 individuals. JAMA Cardiology, 4, pp. 1102-1111. (doi: 10.1001/jamacardio.2019.3593)

Beldhuis, I. E., Streng, K. W., van der Meer, P., Ter Maaten, J. M., O'Connor, C. M., Metra, M., Dittrich, H. C., Ponikowski, P., Cotter, G., Cleland, J. G.F., Davison, B. A., Givertz, M. M., Teerlink, J. R., Bloomfield, D. M., Voors, A. A., Damman, K. (2019) Trajectories of changes in renal function in patients with acute heart failure. Journal of Cardiac Failure, 25, pp. 866-874. (doi: 10.1016/j.cardfail.2019.07.004)

Solomon, S. D. et al. (2019) Angiotensin–neprilysin inhibition in heart failure with preserved ejection fraction. New England Journal of Medicine, 381, pp. 1609-1620. (doi: 10.1056/NEJMoa1908655)

Santema, B. T. et al. (2019) Identifying optimal doses of heart failure medications in men compared with women: a prospective, observational, cohort study. Lancet, 394, (doi: 10.1016/S0140-6736(19)31792-1)

Seferovic, P. M. et al. (2019) Clinical practice update on heart failure 2019: pharmacotherapy, procedures, devices and patient management. An expert consensus meeting report of The Heart Failure Association of the European Society of Cardiology. European Journal of Heart Failure, 21, pp. 1169-1186. (doi: 10.1002/ejhf.1531)

Muilwijk, M., Ho, F., Waddell, H., Sillars, A., Welsh, P., Iliodromiti, S., Brown, R., Ferguson, L., Stronks, K., van Valkengoed, I., Pell, J. P., Gray, S. R., Gill, J. M. R., Sattar, N., Celis-Morales, C. (2019) Contribution of type 2 diabetes to all-cause mortality, cardiovascular disease incidence and cancer incidence in white Europeans and South Asians: findings from the UK Biobank population-based cohort study. BMJ Open Diabetes Research and Care, 7, (doi: 10.1136/bmjdrc-2019-000765)

Yazaki, Y., Salzano, A., Nelson, C. P., Voors, A. A., Anker, S. D., Cleland, J. G., Lang, C. C., Metra, M., Samani, N. J., Ng, L. L., Suzuki, T. (2019) Geographical location affects the levels and association of trimethylamine N‐oxide with heart failure mortality in BIOSTAT‐CHF: a post‐hoc analysis. European Journal of Heart Failure, 21, pp. 1291-1294. (doi: 10.1002/ejhf.1550)

Gatseva, A., Sin, Y. Y., Brezzo, G., Van Agtmael, T. (2019) Basement membrane collagens and disease mechanisms. Essays in Biochemistry, 63, pp. 297-312. (doi: 10.1042/EBC20180071)

Touyz, R. M., Lang, N. N. (2019) Hypertension and antiangiogenesis: the Janus face of VEGF inhibitors. JACC: CardioOncology, 1, pp. 37-40. (doi: 10.1016/j.jaccao.2019.08.010)

Iliodromiti, S., Sattar, N., Delles, C., Nelson, S. M., Gill, J. M.R., Lumsden, M. (2019) Menopausal hot flashing and endothelial function in two vascular beds: findings from a cross-sectional study of postmenopausal women. Menopause, 26, pp. 1002-1009. (doi: 10.1097/GME.0000000000001386)

Ho, F. K.W., Celis-Morales, C. A., Petermann, F., Sillars, A., Welsh, P., Welsh, C., Anderson, J., Lyall, D. M., Mackay, D. F., Sattar, N., Gill, J. M.R., Pell, J. P., Gray, S. R. (2019) The association between handgrip strength and future health outcomes does not differ if grip strength is used in absolute or relative terms: a prospective cohort study. Age and Ageing, 48, pp. 683-691. (doi: 10.1093/ageing/afz068)

Skopalik, S., Hall Barrientos, P., Matthews, J., Radjenovic, A., Mark, P., Roditi, G., Paul, M.C. (2019) FFR and Pressure Drop Assesment across Severe Iliac Artery Stenosis: 4D Fow MRI-based Computational Fluid Dynamics vs. In-vivo Measurements.

Metra, M. et al. (2019) Effects of serelaxin in patients with acute heart failure. New England Journal of Medicine, 381, pp. 716-726. (doi: 10.1056/NEJMoa1801291)

Täger, T., Fröhlich, H., Grundtvig, M., Seiz, M., Schellberg, D., Goode, K., Kazmi, S., Hole, T., Katus, H. A., Atar, D., Cleland, J. G.F., Agewall, S., Clark, A. L., Frankenstein, L. (2019) Comparative effectiveness of loop diuretics on mortality in the treatment of patients with chronic heart failure – a multicenter propensity score matched analysis. International Journal of Cardiology, 289, pp. 83-90. (doi: 10.1016/j.ijcard.2019.01.109)

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2018

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Shah, S. J. et al. (2018) One-year safety and clinical outcomes of a transcatheter interatrial shunt device for the treatment of heart failure with preserved ejection fraction in the reduce elevated left atrial pressure in patients with heart failure (REDUCE LAP-HF I) trial: a randomized clinical trial. JAMA Cardiology, 3, pp. 968-977. (doi: 10.1001/jamacardio.2018.2936)

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Christakoudi, S. et al. (2018) Steroid regulation: an overlooked aspect of tolerance and chronic rejection in kidney transplantation. Molecular and Cellular Endocrinology, 473, pp. 205-216. (doi: 10.1016/j.mce.2018.01.021)

Nagai, T., Sundaram, V., Rothnie, K., Quint, J. K., Shoaib, A., Shiraishi, Y., Kohsaka, S., Piper, S., McDonagh, T. A., Hardman, S. M. C., Goda, A., Mizuno, A., Kohno, T., Rigsby, A. S., Yoshikawa, T., Clark, A. L., Anzai, T., Cleland, J. G.F. (2018) Mortality after admission for heart failure in the United Kingdom compared to Japan. Open Heart, 5, (doi: 10.1136/openhrt-2018-000811)

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Tromp, J., Westenbrink, B. D., Oowerkerk, W., van Veldhuisen, D. J., Samani, N. J., Ponikowski, P., Metra, M., Anker, S. D., Cleland, J. G., Dickstein, K., Filippatos, G., van der Harst, P., Lang, C. C., Ng, L. L., Zannad, F., Zwinderman, A. H., Hillege, H. L., van der Meer, P., Voors, A. A. (2018) Identifying pathophysiological mechanisms in heart failure with reduced versus preserved ejection fraction. Journal of the American College of Cardiology, 72, pp. 1081-1090. (doi: 10.1016/j.jacc.2018.06.050)

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Findlay, M., MacIsaac, R., MacLeod, M. J., Metcalfe, W., Traynor, J. P., Dawson, J., Mark, P. B. (2018) Renal replacement modality and stroke risk in end-stage renal disease—a national registry study. Nephrology Dialysis Transplantation, 33, pp. 1564-1571. (doi: 10.1093/ndt/gfx291)

Gulati, A., Japp, A. G., Raza, S., Halliday, B. P., Jones, D. A., Newsome, S., Ismail, N. A., Morarji, K., Khwaja, J., Spath, N., Shakespeare, C., Kalra, P. R., Lloyd, G., Mathur, A., Cleland, J. G.F., Cowie, M. R., Assomull, R. G., Pennell, D. J., Ismail, T. F., Prasad, S. K. (2018) Absence of myocardial fibrosis predicts favorable long-term survival in new-onset heart failure: a cardiovascular magnetic resonance study. Circulation: Cardiovascular Imaging, 11, (doi: 10.1161/CIRCIMAGING.118.007722)

Ravassa, S., Trippel, T., Bach, D., Bachran, D., González, A., López, B., Wachter, R., Hasenfuss, G., Delles, C., Dominiczak, A. F., Pieske, B., Díez, J., Edelmann, F. (2018) Biomarker-based phenotyping of myocardial fibrosis identifies patients with heart failure with preserved ejection fraction resistant to the beneficial effects of spironolactone: results from the Aldo-DHF trial. European Journal of Heart Failure, 20, pp. 1290-1299. (doi: 10.1002/ejhf.1194)

Carrick, D., Haig, C., Maznyczka, A. M., Carberry, J., Mangion, K., Ahmed, N., May, V. T. Y., McEntegart, M., Petrie, M. C., Eteiba, H., Lindsay, M., Hood, S., Watkins, S., Davie, A., Mahrous, A., Mordi, I., Ford, I., Radjenovic, A., Welsh, P., Sattar, N., Wetherall, K., Oldroyd, K. G., Berry, C. (2018) Hypertension, microvascular pathology and prognosis after an acute myocardial infarction. Hypertension, 72, pp. 720-730. (doi: 10.1161/HYPERTENSIONAHA.117.10786)

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Carberry, J., Carrick, D., Haig, C., Ahmed, N., Mordi, I., McEntegart, M., Petrie, M. C., Eteiba, H., Hood, S., Watkins, S., Lindsay, M., Davie, A., Mahrous, A., Ford, I., Sattar, N., Welsh, P., Radjenovic, A., Oldroyd, K. G., Berry, C. (2018) Persistent iron within the infarct core after ST-segment elevation myocardial infarction: implications for left ventricular remodeling and health outcomes. JACC: Cardiovascular Imaging, 11, pp. 1248-1256. (doi: 10.1016/j.jcmg.2017.08.027)

Divorty, N., Milligan, G., Graham, D., Nicklin, S. A. (2018) The orphan receptor GPR35 contributes to angiotensin II–induced hypertension and cardiac dysfunction in mice. American Journal of Hypertension, 31, pp. 1049-1058. (doi: 10.1093/ajh/hpy073)

Kammer, M., Heinzel, A., Mayer, G., Reindl-Schwaighofer, R., Hu, K., Perco, P., Eder, S., Rosivall, L., Mark, P. B., Ju, W., Kretzler, M., Gilmour, P., Wilson, J. M., Duffin, K. L., Abdalla, M., McCarthy, M. I., Heerspink, H. L., Wiecek, A., Gomez, M. F., Oberbauer, R. (2018) Validation of plasma biomarker candidates for the prediction of eGFR decline in patients with type 2 diabetes. Diabetes Care, 41, pp. 1947-1954. (doi: 10.2337/dc18-0532)

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Gillis, K., Stevens, K. K., Bell, E., Patel, R. K., Jardine, A. G., Morris, S. T.W., Schneider, M. P., Delles, C., Mark, P. B. (2018) Ascorbic acid lowers central blood pressure and asymmetric dimethylarginine in chronic kidney disease. Clinical Kidney Journal, 11, pp. 532-539. (doi: 10.1093/ckj/sfx158)

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Botha, S., Forde, L., MacNaughton, S., Shearer, R., Lindsay, R., Sattar, N., Morrison, D., Welsh, P., Logue, J. (2018) The effect of non-surgical weight management on weight and glycaemic control in people with type 2 diabetes: a comparison of interventional and non-interventional outcomes at three years. Diabetes, Obesity and Metabolism, 20, pp. 879-888. (doi: 10.1111/dom.13171)

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Mark, P., Dekkers, I., Blankestijn, P., Leiner, T., Roditi, G. (2018) Letter on 'European dermatology forum S1-guideline on the diagnosis and treatment of sclerosing diseases of the skin, Part 2: Scleromyxedema, scleredema and nephrogenic systemic fibrosis' Journal of the European Academy of Dermatology and Venereology, 32, pp. e84-e85. (doi: 10.1111/jdv.14774)

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Cleland, J. G.F., Flather, M. D., Altman, D. G., Kotecha, D. (2018) Reply: an incomplete story. Journal of the American College of Cardiology, 71, pp. 105. (doi: 10.1016/j.jacc.2017.10.078)

McCarroll, C. S. et al. (2018) Runx1 deficiency protects against adverse cardiac remodeling after myocardial infarction. Circulation, 137, pp. 57-70. (doi: 10.1161/CIRCULATIONAHA.117.028911)

Cleland, J. G.F., Bunting, K. V., Flather, M. D., Altman, D. G., Holmes, J., Coats, A. J.S., Manzano, L., McMurray, J. J.V., Ruschitzka, F., van Veldhuisen, D. J., von Lueder, T. G., Böhm, M., Andersson, B., Kjekshus, J., Packer, M., Rigby, A. S., Rosano, G., Wedel, H., Hjalmarson, Å., Wikstrand, J., Kotecha, D. (2018) Beta-blockers for heart failure with reduced, mid-range, and preserved ejection fraction: an individual patient-level analysis of double-blind randomized trials. European Heart Journal, 39, pp. 26-35. (doi: 10.1093/eurheartj/ehx564)

Solbu, M. D., Mjøen, G., Mark, P. B., Holdaas, H., Fellström, B., Schmieder, R. E., Zannad, F., Herrington, W. G., Jardine, A. G. (2018) Predictors of atherosclerotic events in patients on haemodialysis: post hoc analyses from the AURORA Study. Nephrology Dialysis Transplantation, 33, pp. 102-112. (doi: 10.1093/ndt/gfw360)

Mark, P. B. (2018) Strategies to manage cardiovascular risk in chronic kidney disease. Nephrology Dialysis Transplantation, 33, pp. 23-25. (doi: 10.1093/ndt/gfx329)

Mangion, K., McDowell, K., Mark, P. B., Rutherford, E. (2018) Characterizing cardiac involvement in chronic kidney disease using CMR—a systematic review. Current Cardiovascular Imaging Reports, 11, (doi: 10.1007/s12410-018-9441-9)

Pellicori, P., Urbinati, A., Zhang, J., Joseph, A. C., Costanzo, P., Lukaschuk, E., Capucci, A., Cleland, J. G.F., Clark, A. L. (2018) Clinical and prognostic relationships of pulmonary artery to aorta diameter ratio in patients with heart failure: a cardiac magnetic resonance imaging study. Clinical Cardiology, 41, pp. 20-27. (doi: 10.1002/clc.22840)

Patel, N., Hellmuth, C., Uhl, O., Godfrey, K., Briley, A., Welsh, P., Pasupathy, D., Seed, P., Koletzko, B., Poston, L. (2018) Cord metabolic profiles In obese pregnant women; insights into offspring growth and body composition. Journal of Clinical Endocrinology and Metabolism, 103, pp. 346-355. (doi: 10.1210/jc.2017-00876)

Stoumpos, S., Hennessy, M., Vesey, A. T., Radjenovic, A., Kasthuri, R., Kingsmore, D. B., Mark, P. B., Roditi, G. (2018) Ferumoxytol-enhanced magnetic resonance angiography for the assessment of potential kidney transplant recipients. European Radiology, 28, pp. 115-123. (doi: 10.1007/s00330-017-4934-5)

Eder, S., Leierer, J., Kerschbaum, J., Rosivall, L., Wiecek, A., de Zeeuw, D., Mark, P. B., Heinze, G., Rossing, P., Heerspink, H. L., Mayer, G. (2018) A prospective cohort study in patients with type 2 diabetes mellitus for validation of biomarkers (PROVALID) –study design and baseline characteristics. Kidney and Blood Pressure Research, 43, pp. 181-190. (doi: 10.1159/000487500)

Delles, C., Carrick, E., Graham, D., Nicklin, S. A. (2018) Utilising proteomics to understand and define hypertension: where are we and where do we go? Expert Review of Proteomics, 15, pp. 581-592. (doi: 10.1080/14789450.2018.1493927)

2017

Celis-Morales, C. A., Petermann, F., Hui, L., Lyall, D. M., Iliodromiti, S., McLaren, J., Anderson, J., Welsh, P., Mackay, D. F., Pell, J. P., Sattar, N., Gill, J. M.R., Gray, S. R. (2017) Associations between diabetes and both cardiovascular disease and all-cause mortality are modified by grip strength: evidence from UK Biobank, a prospective population-based cohort study. Diabetes Care, 40, pp. 1710-1718. (doi: 10.2337/dc17-0921)

Kaye, D. M., Silvestry, F. E., Gustafsson, F., Cleland, J. G., van Veldhuisen, D. J., Ponikowski, P., Komtebedde, J., Nanayakkara, S., Burkhoff, D., Shah, S. J. (2017) Impact of atrial fibrillation on rest and exercise haemodynamics in heart failure with mid-range and preserved ejection fraction. European Journal of Heart Failure, 19, pp. 1690-1697. (doi: 10.1002/ejhf.930)

Carberry, J., Carrick, D., Haig, C., Ahmed, N., Mordi, I., McEntegart, M., Petrie, M. C., Eteiba, H., Hood, S., Watkins, S., Lindsay, M., Davie, A., Mahrous, A., Ford, I., Sattar, N., Welsh, P., Radjenovic, A., Oldroyd, K. G., Berry, C. (2017) Persistence of infarct zone T2 hyperintensity at 6 months after acute ST-elevation myocardial infarction: incidence, pathophysiology and prognostic implications. Circulation: Cardiovascular Imaging, 10, (doi: 10.1161/CIRCIMAGING.117.006586)

Krochmal, M., Kontostathi, G., Magalhães, P., Makridakis, M., Klein, J., Husi, H., Leierer, J., Mayer, G., Bascands, J.-L., Denis, C., Zoidakis, J., Zürbig, P., Delles, C., Schanstra, J. P., Mischak, H., Vlahou, A. (2017) Urinary peptidomics analysis reveals proteases involved in diabetic nephropathy. Scientific Reports, 7, (doi: 10.1038/s41598-017-15359-9)

Vieira, M. C., White, S. L., Patel, N., Seed, P. T., Briley, A. L., Sandall, J., Welsh, P., Sattar, N., Nelson, S. M., Lawlor, D. A., Poston, L., Pasupathy, D. (2017) Prediction of uncomplicated pregnancies in obese women: a prospective multicentre study. BMC Medicine, 15, (doi: 10.1186/s12916-017-0956-8)

Sartini, C., Whincup, P. H., Wannamethee, S. G., Jefferis, B. J., Lennon, L., Lowe, G. D.O., Welsh, P., Sattar, N., Morris, R. W. (2017) Associations of time of day with cardiovascular disease risk factors measured in older men: results from the British Regional Heart Study. BMJ Open, 7, (doi: 10.1136/bmjopen-2017-018264)

Shah, P., Pellicori, P., Macnamara, A., Urbinati, A., Clark, A. L. (2017) Is swimming safe in heart failure? A systematic review. Cardiology in Review, 25, pp. 321-325. (doi: 10.1097/CRD.0000000000000154)

Rutherford, E., Stewart, G., Houston, J. G., Jardine, A. G., Mark, P. B., Struthers, A. D. (2017) An open-label dose-finding study of allopurinol to target defined reduction in urate levels in hemodialysis patients. Journal of Clinical Pharmacology, 57, pp. 1409-1414. (doi: 10.1002/jcph.939)

Mary, S., Kulkarni, M. J., Mehendale, S. S., Joshi, S. R., Giri, A. P. (2017) Differential accumulation of vimentin fragments in preeclamptic placenta. Cytoskeleton, 74, pp. 420-425. (doi: 10.1002/cm.21390)

Pontillo, C. et al. (2017) Prediction of chronic kidney disease stage 3 by CKD273, a urinary proteomic biomarker. Kidney International Reports, 2, pp. 1066-1075. (doi: 10.1016/j.ekir.2017.06.004)

Welsh, P., Grassia, G., Botha, S., Sattar, N., Maffia, P. (2017) Targeting inflammation to reduce cardiovascular disease risk: a realistic clinical prospect? British Journal of Pharmacology, 174, pp. 3898-3913. (doi: 10.1111/bph.13818)

Schmieder, R. E., Wagner, F., Mayr, M., Delles, C., Ott, C., Keicher, C., Hrabak-Paar, M., Heye, T., Aichner, S., Khder, Y., Yates, D., Albrecht, D., Langenickel, T., Freyhardt, P., Janka, R., Bremerich, J. (2017) The effect of sacubitril/valsartan compared to olmesartan on cardiovascular remodelling in subjects with essential hypertension: the results of a randomized, double-blind, active-controlled study. European Heart Journal, 38, pp. 3308-3317. (doi: 10.1093/eurheartj/ehx525)

Rutherford, E., Mangion, K., Mccomb, C., Bell, E., Cockburn, S., Talle, M., Roditi, G., Welsh, P., Woodward, R., Radjenovic, A., Struthers, A. D., Jardine, A., Berry, C., Patel, R. K., Mark, P. B. (2017) Myocardial changes in incident haemodialysis patients over 6-months: an observational cardiac magnetic resonance imaging study. Scientific Reports, 7, (doi: 10.1038/s41598-017-14481-y)

Bayes-Genis, A., Núñez, J., Zannad, F., Ferreira, J. P., Anker, S. D., Cleland, J. G., Dickstein, K., Filippatos, G., Lang, C. C., Ng, L. L., Ponikowski, P., Samani, N. J., van Veldhuisen, D. J., Zwinderman, A. H., Metra, M., Lupón, J., Voors, A. A. (2017) The PCSK9-LDL receptor axis and outcomes in heart failure: BIOSTAT-CHF subanalysis. Journal of the American College of Cardiology, 70, pp. 2128-2136. (doi: 10.1016/j.jacc.2017.08.057)

Kohli-Lynch, C.N., Boyd, K., Briggs, A., Delles, C. (2017) A Framework for the Cost-Effectiveness Analysis of Novel Biomarker Testing in Cardiovascular Disease. (doi: 10.1016/j.jval.2017.08.040)

Sharma, A., Demissei, B. G., Tromp, J., Hillege, H. L., Cleland, J. G.F., O'Connor, C. M., Metra, M., Ponikowski, P., Teerlink, J. R., Davison, B. A., Givertz, M. M., Bloomfield, D. M., Dittrich, H., van Veldhuisen, D. J., Cotter, G., Ezekowitz, J. A., Khan, M. A.F., Voors, A. A. (2017) A network analysis to compare biomarker profiles in patients with and without diabetes mellitus in acute heart failure. European Journal of Heart Failure, 19, pp. 1310-1320. (doi: 10.1002/ejhf.912)

Stevens, K., Denby, L., Patel, R. K., Mark, P. B., Kettlewell, S., Smith, G. L., Clancy, M. J., Delles, C., Jardine, A. G. (2017) Deleterious effects of phosphate on vascular and endothelial function via disruption to the nitric oxide pathway. Nephrology Dialysis Transplantation, 32, pp. 1617-1627. (doi: 10.1093/ndt/gfw252)

White, S. L., Pasupathy, D., Sattar, N., Nelson, S. M., Lawlor, D. A., Briley, A. L., Seed, P. T., Welsh, P., Poston, L. (2017) Metabolic profiling of gestational diabetes in obese women during pregnancy. Diabetologia, 60, pp. 1903-1912. (doi: 10.1007/s00125-017-4380-6)

Ferreira, J. P., Rossignol, P., Machu, J.-L., Sharma, A., Girerd, N., Anker, S. D., Cleland, J. G., Dickstein, K., Filippatos, G., Hillege, H. L., Lang, C. C., Ter Maaten, J., Metra, M., Ng, L., Ponikowski, P., Samani, N. J., van Veldhuisen, D. J., Zwinderman, A. H., Voors, A., Zannad, F. (2017) Mineralocorticoid receptor antagonist pattern of use in heart failure with reduced ejection fraction: findings from BIOSTAT-CHF. European Journal of Heart Failure, 19, pp. 1284-1293. (doi: 10.1002/ejhf.900)

Nassif, M. E., Tang, Y., Cleland, J. G.F., Abraham, W. T., Linde, C., Gold, M. R., Young, J. B., Daubert, J. C., Sherfesee, L., Schaber, D., Tang, A. S.L., Jones, P. G., Arnold, S. V., Spertus, J. A. (2017) Precision medicine for cardiac resynchronization: predicting quality of life benefits for individual patients-an analysis from 5 clinical trials. Circulation: Heart Failure, 10, (doi: 10.1161/CIRCHEARTFAILURE.117.004111)

Cleland, J. G.F., Halliday, B. P., Prasad, S. K. (2017) Selecting patients with nonischemic dilated cardiomyopathy for ICDs. Journal of the American College of Cardiology, 70, pp. 1228-1231. (doi: 10.1016/j.jacc.2017.07.748)

Noh, R. M., Venkatasubramanian, S., Daga, S., Langrish, J., Mills, N. L., Lang, N. N., Hoffmann, E., Waterhouse, B., Newby, D. E., Frier, B. M. (2017) Cardiometabolic effects of a novel SIRT1 activator, SRT2104, in people with type 2 diabetes mellitus. Open Heart, 4, (doi: 10.1136/openhrt-2017-000647)

Fröhlich, H., Torres, L., Täger, T., Schellberg, D., Corletto, A., Kazmi, S., Goode, K., Grundtvig, M., Hole, T., Katus, H. A., Cleland, J. G.F., Atar, D., Clark, A. L., Agewall, S., Frankenstein, L. (2017) Bisoprolol compared with carvedilol and metoprolol succinate in the treatment of patients with chronic heart failure. Clinical Research in Cardiology, 106, pp. 711-721. (doi: 10.1007/s00392-017-1115-0)

Wannamethee, S. G., Welsh, P., Papacosta, O., Ellins, E. A., Halcox, J. P.J., Whincup, P. H., Sattar, N. (2017) Circulating soluble receptor for advanced glycation end product: cross-sectional associations with cardiac markers and subclinical vascular disease in older men with and without diabetes. Atherosclerosis, 264, pp. 36-43. (doi: 10.1016/j.atherosclerosis.2017.07.008)

Price, A. H., Weir, C. J., Welsh, P., McLachlan, S., Strachan, M. W.J., Sattar, N., Price, J. F. (2017) Comparison of non-traditional biomarkers, and combinations of biomarkers, for vascular risk prediction in people with type 2 diabetes: The Edinburgh Type 2 Diabetes Study. Atherosclerosis, 264, pp. 67-73. (doi: 10.1016/j.atherosclerosis.2017.07.009)

Cleland, J. G.F. (2017) Does aspirin detract from the benefits of mineralocorticoid receptor antagonists in patients with heart failure and a reduced left ventricular ejection fraction? Probably! European Journal of Heart Failure, 19, pp. 1086-1088. (doi: 10.1002/ejhf.697)

Koudstaal, S., Pujades-Rodriguez, M., Denaxas, S., Gho, J. M.I.H., Shah, A. D., Yu, N., Patel, R. S., Gale, C. P., Hoes, A. W., Cleland, J. G.F., Asselbergs, F. W., Hemingway, H. (2017) Prognostic burden of heart failure recorded in primary care, acute hospital admissions, or both: a population-based linked electronic health record cohort study in 2.1 million people. European Journal of Heart Failure, 19, pp. 1119-1127. (doi: 10.1002/ejhf.709)

Sanders, M. F., van Doormaal, P. J., Beeftink, M. M.A., Bots, M. L., Fadl Elmula, F. E. M., Habets, J., Hammer, F., Hoffmann, P., Jacobs, L., Mark, P. B., Persu, A., Renkin, J., Roditi, G., Spiering, W., Staessen, J. A., Taylor, A. H., Verloop, W. L., Vink, E. E., Vonken, E.-J., Voskuil, M., Leiner, T., Blankestijn, P. J. (2017) Renal artery and parenchymal changes after renal denervation: assessment by magnetic resonance angiography. European Radiology, 27, pp. 3934-3941. (doi: 10.1007/s00330-017-4770-7)

Krochmal, M., Cisek, K., Filip, S., Markoska, K., Orange, C., Zoidakis, J., Gakiopoulou, C., Spasovski, G., Mischak, H., Delles, C., Vlahou, A., Jankowski, J. (2017) Identification of novel molecular signatures of IgA nephropathy through an integrative -omics analysis. Scientific Reports, 7, (doi: 10.1038/s41598-017-09393-w)

Willeit, P., Welsh, P., Evans, J. D.W., Tschiderer, L., Boachie, C., Jukema, J. W., Ford, I., Trompet, S., Stott, D. J., Kearney, P. M., Mooijaart, S. P., Kiechl, S., Di Angelantonio, E., Sattar, N. (2017) High-sensitivity cardiac troponin concentration and risk of first-ever cardiovascular outcomes: literature-based meta-analysis involving 154,052 participants. Journal of the American College of Cardiology, 70, pp. 558-568. (doi: 10.1016/j.jacc.2017.05.062)

Bhat, S., Mary, S., Giri, A. P., Kulkarni, M. J. (2017) Advanced glycation end products (AGEs) in diabetic complications. Springer

Jenks, S. J., Conway, B. R., McLachlan, S., Teoh, W. L., Williamson, R. M., Webb, D. J., Welsh, P., Sattar, N., Strachan, M. W.J., Price, J. F. (2017) Cardiovascular disease biomarkers are associated with declining renal function in type 2 diabetes. Diabetologia, 60, pp. 1400-1408. (doi: 10.1007/s00125-017-4297-0)

Gimpelewicz, C., Metra, M., Cleland, J. G.F., Szecsödy, P., Chang Wun, C.-C., Boer-Martins, L., Cotter, G., Davison, B. A., Felker, G. M., Filippatos, G., Greenberg, B. H., Pang, P., Ponikowski, P., Severin, T., Voors, A. A., Teerlink, J. R. (2017) Effects of serelaxin on the outcome of patients with or without substantial peripheral edema: a subgroup analysis from the RELAX-AHF trial. American Heart Journal, 190, pp. 113-122. (doi: 10.1016/j.ahj.2017.05.012)

Currie, G., Delles, C. (2017) Healthy vascular ageing. Hypertension, 70, pp. 229-231. (doi: 10.1161/HYPERTENSIONAHA.117.09122)

Small, H. Y., Cornelius, D. C., Guzik, T. J., Delles, C. (2017) Natural killer cells in placentation and cancer: Implications for hypertension during pregnancy. Placenta, 56, pp. 59-64. (doi: 10.1016/j.placenta.2017.03.003)

Zhang, Z.‐Y., Ravassa, S., Nkuipou‐Kenfack, E., Yang, W.-Y., Kerr, S. M., Koeck, T., Campbell, A., Kuznetsova, T., Mischak, H., Padmanabhan, S., Dominiczak, A. F., Delles, C., Staessen, J. A. (2017) Novel urinary peptidomic classifier predicts incident heart failure. Journal of the American Heart Association, 6, (doi: 10.1161/JAHA.116.005432)

Linde, C., Abraham, W. T., Gold, M. R., Daubert, C., Tang, A. S.L., Young, J. B., Sherfesee, L., Hudnall, H., Fagan, D. H., Cleland, J. G. (2017) Predictors of short-term clinical response to cardiac resynchronization therapy. European Journal of Heart Failure, 19, pp. 1056-1063. (doi: 10.1002/ejhf.795)

Gajjala, P. R., Jankowski, V., Heinze, G., Bilo, G., Zanchetti, A., Noels, H., Liehn, E., Perco, P., Schulz, A., Delles, C., Kork, F., Biessen, E., Narkiewicz, K., Kawecka-Jaszcz, K., Floege, J., Soranna, D., Zidek, W., Jankowski, J. (2017) Proteomic-biostatistic integrated approach for finding the underlying molecular determinants of hypertension in human plasma. Hypertension, 70, pp. 412-419. (doi: 10.1161/HYPERTENSIONAHA.116.08906)

Touyz, R. M., Lang, N. N., Herrmann, J., van den Meiracker, A. H., Danser, A.H. J. (2017) Recent advances in hypertension and cardiovascular toxicities with vascular endothelial growth factor inhibition. Hypertension, 70, pp. 220-226. (doi: 10.1161/HYPERTENSIONAHA.117.08856)

Lees, J. S., McQuarrie, E. P., Mordi, N., Geddes, C. C., Fox, J. G., Mackinnon, B. (2017) Risk factors for bleeding complications after nephrologist-performed native renal biopsy. Clinical Kidney Journal, 10, pp. 573-577. (doi: 10.1093/ckj/sfx012)

Cleland, J. G.F. (2017) What do cardiology and homeopathy have in common? : A belief in aspirin? JACC: Heart Failure, 5, pp. 611-614. (doi: 10.1016/j.jchf.2017.06.009)

Knez, J., Marrachelli, V. G., Cauwenberghs, N., Winckelmans, E., Zhang, Z., Thijs, L., Brguljan-Hitij, J., Plusquin, M., Delles, C., Monleon, D., Redón, J., Staessen, J. A., Nawrot, T. S., Kuznetsova, T. (2017) Peripheral blood mitochondrial DNA content in relation to circulating metabolites and inflammatory markers: a population study. PLoS ONE, 12, (doi: 10.1371/journal.pone.0181036)

Halliday, B. P., Cleland, J. G.F., Goldberger, J. J., Prasad, S. K. (2017) Personalizing sudden death risk stratification in dilated cardiomyopathy: past, present and future. Circulation, 136, pp. 215-231. (doi: 10.1161/CIRCULATIONAHA.116.027134)

Damman, K., Valente, M. A.E., van Veldhuisen, D. J., Cleland, J. G.F., O’Connor, C. M., Metra, M., Ponikowski, P., Cotter, G., Davison, B., Givertz, M. M., Bloomfield, D. M., Hillege, H. L., Voors, A. A. (2017) Plasma neutrophil gelatinase-associated lipocalin and predicting clinically relevant worsening renal function in acute heart failure. International Journal of Molecular Sciences, 18, (doi: 10.3390/ijms18071470)

Janowitz, T., Williams, E. H., Marshall, A., Ainsworth, N., Thomas, P. B., Sammut, S. J., Shepherd, S., White, J., Mark, P. B., Lynch, A. G., Jodrell, D. I., Tavaré, S., Earl, H. (2017) New model for estimating glomerular filtration rate in patients with cancer. Journal of Clinical Oncology, (doi: 10.1200/JCO.2017.72.7578)

Ohkuma, T., Jun, M., Woodward, M., Zoungas, S., Cooper, M. E., Grobbee, D. E., Hamet, P., Mancia, G., Williams, B., Welsh, P., Sattar, N., Shaw, J. E., Rahimi, K., Chalmers, J. (2017) Cardiac stress and inflammatory markers as predictors of heart failure in patients with type 2 diabetes: the ADVANCE trial. Diabetes Care, 40, pp. 1203-1209. (doi: 10.2337/dc17-0509)

Shen, L., Jhund, P. S., Petrie, M. C., Claggett, B. L., Barlera, S., Cleland, J. G.F., Dargie, H. J., Granger, C. B., Kjekshus, J., Køber, L., Latini, R., Maggioni, A. P., Packer, M., Pitt, B., Solomon, S. D., Swedberg, K., Tavazzi, L., Wikstrand, J., Zannad, F., Zile, M. R., McMurray, J. J.V. (2017) Declining risk of sudden death in heart failure. New England Journal of Medicine, 377, pp. 41-51. (doi: 10.1056/NEJMoa1609758)

Findlay, M. D., Mark, P. B. (2017) Reduced and declining physical function in prevalent dialysis patients – identifying the vulnerable. Age and Ageing, 46, pp. 541-543. (doi: 10.1093/ageing/afx049)

Fröhlich, H., Raman, N., Täger, T., Schellberg, D., Goode, K. M., Kazmi, S., Grundtvig, M., Hole, T., Cleland, J. G.F., Katus, H. A., Agewall, S., Clark, A. L., Atar, D., Frankenstein, L. (2017) Statins attenuate but do not eliminate the reverse epidemiology of total serum cholesterol in patients with non-ischemic chronic heart failure. International Journal of Cardiology, 238, pp. 97-104. (doi: 10.1016/j.ijcard.2017.03.028)

Tromp, J., Khan, M. A. F., Mentz, R. J., O'Connor, C. M., Metra, M., Dittrich, H. C., Ponikowski, P., Teerlink, J. R., Cotter, G., Davison, B., Cleland, J. G.F., Givertz, M. M., Bloomfield, D. M., Van Veldhuisen, D. J., Hillege, H. L., Voors, A. A., van der Meer, P. (2017) Biomarker profiles of acute heart failure patients with a mid-range ejection fraction. JACC: Heart Failure, 5, pp. 507-517. (doi: 10.1016/j.jchf.2017.04.007)

Pellicori, P., Clark, A. L., Kallvikbacka-Bennett, A., Zhang, J., Urbinati, A., Monzo, L., Dierckx, R., Anker, S. D., Cleland, J. G.F. (2017) Non-invasive measurement of right atrial pressure by near-infrared spectroscopy: preliminary experience. A report from the SICA-HF study. European Journal of Heart Failure, 19, pp. 883-892. (doi: 10.1002/ejhf.825)

Sze, S., Zhang, J., Pellicori, P., Morgan, D., Hoye, A., Clark, A.L. (2017) Prognostic value of simple frailty and malnutrition screening tools in patients with acute heart failure due to left ventricular systolic dysfunction. Clinical Research in Cardiology, 106, pp. 533-541. (doi: 10.1007/s00392-017-1082-5)

Wang, D., Mohammad, M., Wang, Y., Tan, R., Murray, L. S., Ricardo, S., Dagher, H., van Agtmael, T., Savige, J. (2017) The chemical chaperone, PBA, reduces ER stress and autophagy and increases collagen IV α5 expression in cultured fibroblasts from men with X-linked Alport syndrome and missense mutations. Kidney International Reports, 2, pp. 739-748. (doi: 10.1016/j.ekir.2017.03.004)

Cleland, J. G.F., Pellicori, P., Clark, A. L., Petrie, M. C. (2017) Time to take the failure out of heart failure: the importance of optimism. JACC: Heart Failure, 5, pp. 538-540. (doi: 10.1016/j.jchf.2017.04.003)

Ouwerkerk, W., Voors, A.A., Anker, S.D., Cleland, J.G., Dickstein, K., Filippatos, G., van der Harst, P., Hillege, H.L., Lang, C.C., ter Maaten, J.M., Ng, L.L., Ponikowski, P., Samani, N.J., van Veldhuisen, D.J., Zannad, F., Metra, M., Zwinderman, A.H. (2017) Determinants and clinical outcome of uptitration of ACE-inhibitor and beta-blocker in patients with heart failure: a prospective European study. European Heart Journal, 38, pp. 1883-1890. (doi: 10.1093/eurheartj/ehx026)

Kotecha, D., Flather, M. D., Altman, D. G., Holmes, J., Rosano, G., Wikstrand, J., Packer, M., Coats, A. J.S., Manzano, L., Böhm, M., van Veldhuisen, D. J., Andersson, B., Wedel, H., von Lueder, T. G., Rigby, A. S., Hjalmarson, Å., Kjekshus, J., Cleland, J. G.F. (2017) Heart rate, heart rhythm and prognostic benefits of beta-blockers in heart failure: individual patient-data meta-analysis. Journal of the American College of Cardiology, 69, pp. 2885-2896. (doi: 10.1016/j.jacc.2017.04.001)

Harvey, A. P., Montezano, A. C., Hood, K. Y., Lopes, R. A., Rios, F., Ceravolo, G., Graham, D., Touyz, R. M. (2017) Vascular dysfunction and fibrosis in stroke-prone spontaneously hypertensive rats: the aldosterone-mineralocorticoid receptor-Nox1 Axis. Life Sciences, 179, pp. 110-119. (doi: 10.1016/j.lfs.2017.05.002)

Baker, R. J., Mark, P. B., Patel, R. K., Stevens, K. K., Palmer, N. (2017) Renal association clinical practice guideline in post-operative care in the kidney transplant recipient. BMC Nephrology, 18, (doi: 10.1186/s12882-017-0553-2)

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Shah, P., Pellicori, P., Cuthbert, J., Clark, A. L. (2017) Pharmacological and non-pharmacological treatment for decompensated heart failure: what is new? Current Heart Failure Reports, 14, pp. 147-157. (doi: 10.1007/s11897-017-0328-x)

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Pellicori, P., Urbinati, A., Shah, P., MacNamara, A., Kazmi, S., Dierckx, R., Zhang, J., Cleland, J. G.F., Clark, A. L. (2017) What proportion of patients with chronic heart failure are eligible for sacubitril-valsartan? European Journal of Heart Failure, 19, pp. 768-778. (doi: 10.1002/ejhf.788)

Halliday, B. P. et al. (2017) Association between mid-wall late gadolinium enhancement and sudden cardiac death in patients with dilated cardiomyopathy and mild and moderate left ventricular systolic dysfunction. Circulation, 135, pp. 2106-2115. (doi: 10.1161/CIRCULATIONAHA.116.026910)

Neisius, U., Olson, E., Rossi, S. H., Ibrahim, H. A., Currie, G., Dominiczak, A., Delles, C. (2017) Evaluation of the systemic micro- and macrovasculature in stable angina: a case-control study. PLoS ONE, 12, (doi: 10.1371/journal.pone.0178412)

Ptinopoulou, A. G., Pikilidou, M. I., Tziolas, I. M., Haidich, A.-B., Mark, P. B., Zebekakis, P. E., Lasaridis, A. N. (2017) Changes in kidney function in a population with essential hypertension in real life settings. Iranian Journal of Kidney Disease, 11, pp. 192-200.

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Dominiczak, A., Delles, C., Padmanabhan, S. (2017) Genomics and precision medicine for clinicians and scientists in hypertension. Hypertension, 69, pp. e10-e13. (doi: 10.1161/HYPERTENSIONAHA.116.08252)

Sarafidis, P. A. et al. (2017) Hypertension in dialysis patients: a consensus document by the European Renal and Cardiovascular Medicine (EURECA-m) working group of the European Renal Association - European Dialysis and Transplant Association (ERA-EDTA) and the Hypertension and the Kidney working group of the European Society of Hypertension (ESH) Journal of Hypertension, 35, pp. 657-676. (doi: 10.1097/HJH.0000000000001283)

Sarafidis, P. A. et al. (2017) Hypertension in dialysis patients: a consensus document by the European Renal and Cardiovascular Medicine (EURECA-m) working group of the European Renal Association-European Dialysis and Transplant Association (ERA-EDTA) and the Hypertension and the Kidney working group of the European Society of Hypertension (ESH) Nephrology Dialysis Transplantation, 32, pp. 620-640. (doi: 10.1093/ndt/gfw433)

Filippatos, G. S. et al. (2017) Independent academic data monitoring committees for clinical trials in cardiovascular and cardiometabolic diseases. European Journal of Heart Failure, 19, pp. 449-456. (doi: 10.1002/ejhf.761)

Skobel, E., Knackstedt, C., Martinez-Romero, A., Salvi, D., Vera-Munoz, C., Napp, A., Luprano, J., Bover, R., Glöggler, S., Bjarnason-Wehrens, B., Marx, N., Rigby, A., Cleland, J. G.F. (2017) Internet-based training of coronary artery patients: the Heart Cycle Trial. Heart and Vessels, 32, pp. 408-418. (doi: 10.1007/s00380-016-0897-8)

Nymo, S. H., Aukrust, P., Kjekshus, J., McMurray, J. J.V., Cleland, J. G.F., Wikstrand, J., Muntendam, P., Wienhues-Thelen, U., Latini, R., Tandberg Askevold, E., Gravning, J., Dahl, C. P., Broch, K., Yndestad, A., Gullestad, L., Ueland, T. (2017) Limited added value of circulating inflammatory biomarkers in chronic heart failure. JACC: Heart Failure, 5, pp. 256-264. (doi: 10.1016/j.jchf.2017.01.008)

Urbinati, A., Pellicori, P., Guerra, F., Capucci, A., Clark, A. L. (2017) Takotsubo syndrome in the paediatric population. Journal of Cardiovascular Medicine, 18, pp. 262-267. (doi: 10.2459/JCM.0000000000000446)

Cleland, J. G.F., Mueller, C. (2017) What can we learn from SOCRATES: more questions than answers? European Heart Journal, 38, pp. 1128-1131. (doi: 10.1093/eurheartj/ehw561)

Rao, M. P., Al-Khatib, S. M., Pokorney, S., She, L., Romanov, A., Nicolau, J. C., Lee, K. L., Carson, P. E., Selzman, C. H., Stepinska, J., Cleland, J. G.F., Tungsubutra, W., Desvigne-Nickens, P. M., Sueta, C., Siepe, M., Lang, I. M., Feldman, A. M., Yii, M., Rouleau, J. L., Velazquez, E. J. (2017) Sudden cardiac death in patients with ischemic heart failure undergoing coronary artery bypass grafting results from the STICH randomized clinical trial (Surgical Treatment for Ischemic Heart Failure) Circulation, 135, pp. 1136-1144. (doi: 10.1161/CIRCULATIONAHA.116.026075)

Mary, S., Kulkarni, M. J., Mehendale, S. S., Joshi, S. R., Giri, A. P. (2017) Tubulointerstitial nephritis antigen-like 1 protein is downregulated in the placenta of pre-eclamptic women. Clinical Proteomics, 14, (doi: 10.1186/s12014-017-9144-2)

Dovancescu, S., Pellicori, P., Mabote, T., Torabi, A., Clark, A. L., Cleland, J. G.F. (2017) The effects of short-term omission of daily medication on the pathophysiology of heart failure. European Journal of Heart Failure, (doi: 10.1002/ejhf.748)

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Matsue, Y., van der Meer, P., Damman, K., Metra, M., O'Connor, C. M., Ponikowski, P., Teerlink, J. R., Cotter, G., Davison, B., Cleland, J. G.F., Givertz, M. M., Bloomfield, D. M., Dittrich, H. C., Gansevoort, R. T., Bakker, S. J.L., van der Harst, P., Hillege, H. L., van Veldhuisen, D. J., Voors, A. A. (2017) Blood urea nitrogen-to-creatinine ratio in the general population and in patients with acute heart failure. Heart, 103, pp. 407-413. (doi: 10.1136/heartjnl-2016-310112)

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Small, H. Y., Akehurst, C., Sharafetdinova, L., McBride, M. W., McClure, J. D., Robinson, S. W., Carty, D. M., Freeman, D. J., Delles, C. (2017) HLA gene expression is altered in whole blood and placenta from women who later developed preeclampsia. Physiological Genomics, 49, pp. 193-200. (doi: 10.1152/physiolgenomics.00106.2016)

Cuthbert, J. J., Pellicori, P., Shah, P., Clark, A. L. (2017) New pharmacological approaches in heart failure therapy: developments and possibilities. Future Cardiology, 13, pp. 173-188. (doi: 10.2217/fca-2016-0068)

Parsons, T. J., Sartini, C., Welsh, P., Sattar, N., Ash, S., Lennon, L. T., Wannamethee, S. G., Lee, I.-M., Whincup, P. H., Jefferis, B. J. (2017) Physical activity, sedentary behavior, and inflammatory and hemostatic markers in men. Medicine and Science in Sports and Exercise, 49, pp. 459-465. (doi: 10.1249/MSS.0000000000001113)

Sartini, C., Barry, S. J.E., Whincup, P. H., Wannamethee, S. G., Lowe, G. D.O., Jefferis, B. J., Lennon, L., Welsh, P., Ford, I., Sattar, N., Morris, R. W. (2017) Relationship between outdoor temperature and cardiovascular disease risk factors in older people. European Journal of Preventive Cardiology, 24, pp. 349-356. (doi: 10.1177/2047487316682119)

Masters, J., Morton, G., Anton, I., Szymanski, J., Greenwood, E., Grogono, J., Flett, A. S., Cleland, J. G.F., Cowburn, P. J. (2017) Specialist intervention is associated with improved patient outcomes in patients with decompensated heart failure: evaluation of the impact of a multidisciplinary inpatient heart failure team. Open Heart, 4, (doi: 10.1136/openhrt-2016-000547)

Preiss, D., Dawed, A., Welsh, P., Heggie, A., Jones, A. G., Dekker, J., Koivula, R., Hansen, T. H., Stewart, C., Holman, R. R., Franks, P. W., Walker, M., Pearson, E. R., Sattar, N. (2017) Sustained influence of metformin therapy on circulating glucagon-like peptide-1 levels in individuals with and without type 2 diabetes. Diabetes, Obesity and Metabolism, 19, pp. 356-363. (doi: 10.1111/dom.12826)

Dierckx, R., Inglis, S. C., Clark, R. A., Prieto-Merino, D., Cleland, J. G.F. (2017) Telemedicine in heart failure: new insights from the Cochrane meta-analyses. European Journal of Heart Failure, 19, pp. 304-306. (doi: 10.1002/ejhf.759)

Currie, G., Delles, C. (2017) The future of "omics" in hypertension. Canadian Journal of Cardiology, 33, pp. 601-610. (doi: 10.1016/j.cjca.2016.11.023)

Carty, D. M., Doogan, F., Welsh, P., Dominiczak, A. F., Delles, C. (2017) Thyroid stimulating hormone (TSH) ≥2.5mU/l in early pregnancy: prevalence and subsequent outcomes. European Journal of Obstetrics and Gynecology and Reproductive Biology, 210, pp. 366-369. (doi: 10.1016/j.ejogrb.2017.01.048)

Rutherford, E., Mark, P.B. (2017) What happens to the heart in chronic kidney disease? Journal of the Royal College of Physicians of Edinburgh, 47, pp. 76-82. (doi: 10.4997/JRCPe.2017.117)

Graham-Brown, M. P.M., Rutherford, E., Levelt, E., March, D. S., Churchward, D. R., Stensel, D. J., McComb, C., Mangion, K., Cockburn, S., Berry, C., Moon, J. C., Mark, P. B., Burton, J. O., McCann, G. P. (2017) Native T1 mapping: inter-study, inter-observer and inter-center reproducibility in hemodialysis patients. Journal of Cardiovascular Magnetic Resonance, 19, (doi: 10.1186/s12968-017-0337-7)

Mary, S., Kulkarni, M. J., Malakar, D., Joshi, S. R., Mehendale, S. S., Giri, A. P. (2017) Placental proteomics provides insights into pathophysiology of pre-eclampsia and predicts possible markers in plasma. Journal of Proteome Research, 16, pp. 1050-1060. (doi: 10.1021/acs.jproteome.6b00955)

Emdin, C. A., Hsiao, A. J., Kiran, A., Conrad, N., Salimi-Khorshidi, G., Woodward, M., Anderson, S. G., Mohseni, H., McMurray, J. J.V., Cleland, J. G.F., Dargie, H., Hardman, S., McDonagh, T., Rahimi, K. (2017) Referral for specialist follow-up and its association with post-discharge mortality among patients with systolic heart failure (from the National Heart Failure Audit for England and Wales) American Journal of Cardiology, 119, pp. 440-444. (doi: 10.1016/j.amjcard.2016.10.021)

Koh-Tan, H.H. C., Dashti, M., Wang, T., Beattie, W., Mcclure, J., Young, B., Dominiczak, A. F., McBride, M. W., Graham, D. (2017) Dissecting the genetic components of a quantitative trait locus for blood pressure and renal pathology on rat chromosome 3. Journal of Hypertension, 35, pp. 319-329. (doi: 10.1097/HJH.0000000000001155)

Gastelurrutia, P., Lupón, J., Domingo, M., Stut, W., Dovancescu, S., Cleland, J., Frankenstein, L., Bayes-Genis, A. (2017) Potential role for clinical calibration to increase engagement with and application of home telemonitoring: a report from the HeartCycle programme. ESC Heart Failure, 4, pp. 66-70. (doi: 10.1002/ehf2.12104)

Zhang, J., Dierckx, R., Mohee, K., Clark, A. L., Cleland, J. G.F. (2017) Xanthine oxidase inhibition for the treatment of cardiovascular disease: an updated systematic review and meta-analysis. ESC Heart Failure, 4, pp. 40-45. (doi: 10.1002/ehf2.12112)

Delles, C., Husi, H. (2017) Systems biology approach in hypertension research. Springer

Tsiropoulou, S., McBride, M., Padmanabhan, S. (2017) Urine metabolomics in hypertension research. Springer

Mancini, S. J., White, A. D., Bijland, S., Rutherford, C., Graham, D., Richter, E. A., Viollet, B., Touyz, R. M., Palmer, T. M., Salt, I. P. (2017) Activation of AMP-activated protein kinase rapidly suppresses multiple pro-inflammatory pathways in adipocytes including IL-1 receptorassociated kinase-4 phosphorylation. Molecular and Cellular Endocrinology, 440, pp. 44-56. (doi: 10.1016/j.mce.2016.11.010)

Streng, K. W., ter Maaten, J. M., Cleland, J. G.F., O’Connor, C. M., Davison, B. A., Metra, M., Givertz, M. M., Teerlink, J. R., Ponikowski, P., Bloomfield, D. M., Dittrich, H. C., Hillege, H. L., van Veldhuisen, D. J., Voors, A. A., van der Meer, P. (2017) Associations of body mass index with laboratory and biomarkers in patients with acute heart failure. Circulation: Heart Failure, 10, (doi: 10.1161/CIRCHEARTFAILURE.116.003350)

Stoumpos, S., Mark, P. B., McQuarrie, E. P., Traynor, J. P., Geddes, C. C. (2017) Continued monitoring of acute kidney injury survivors might not be necessary in those regaining an estimated glomerular filtration rate > 60 mL/min at 1 year. Nephrology Dialysis Transplantation, 32, pp. 81-88. (doi: 10.1093/ndt/gfw413)

Rutherford, E., Weir-McCall, J. R., Patel, R. K., Houston, J. G., Roditi, G., Struthers, A. D., Jardine, A. G., Mark, P. B. (2017) Research cardiac magnetic resonance imaging in end stage renal disease - incidence, significance and implications of unexpected incidental findings. European Radiology, 27, pp. 315-324. (doi: 10.1007/s00330-016-4288-4)

Tromp, J., ter Maaten, J., Damman, K., O’Connor, C. M., Metra, M., Dittrich, H. C., Ponikowski, P., Teerlink, J. R., Cotter, G., Davison, B., Cleland, J. G.F., Givertz, M. M., Bloomfield, D. M., van der Wal, M. H.L., Jaarsma, T., van Veldhuisen, D. J., Hillege, H. L., Voors, A. A., van der Meer, P. (2017) Serum potassium levels and outcome in acute heart failure (data from the PROTECT and COACH trials) American Journal of Cardiology, 119, pp. 290-296. (doi: 10.1016/j.amjcard.2016.09.038)

Cameron, A. C., Lang, N. N., Touyz, R. M. (2017) Cardiovascular complications from cancer therapy: hypertension-focus on vascular endothelial growth factor inhibitors. Elesvier

Delles, C., Vanholder, R. (2017) Chronic kidney disease. Clinical Science, 131, pp. 225-226. (doi: 10.1042/CS20160624)

Celis-Morales, C., Lyall, D. M., Gray, S., Steell, L., Anderson, J., Iliodromiti, S., Welsh, P., Guo, Y., Petermann, F., Mackay, D. F., Bailey, M. E.S., Pell, J., Gill, J. M.R., Sattar, N. (2017) Dietary fat and total energy intake modifies the association of genetic profile risk score on obesity: evidence from 48 170 UK Biobank participants. International Journal of Obesity, 41, pp. 1761-1768. (doi: 10.1038/ijo.2017.169)

Cuthbert, J. J., Pellicori, P., Clark, A. L. (2017) Interatrial shunt devices for heart failure with normal ejection fraction: a technology update. Medical Devices: Evidence and Research, 10, pp. 123-132. (doi: 10.2147/mder.s113105)

Arain, F., Gullestad, L., Nymo, S., Kjekshus, J., Cleland, J. G.F., Michelsen, A., McMurray, J. J.V., Wikstrand, J., Aukrust, P., Ueland, T. (2017) Low YKL-40 in Chronic Heart Failure may predict beneficial effects of statins: Analysis from the Controlled Rosuvastatin Multinational Trial in Heart Failure (CORONA) Biomarkers, 22, pp. 261-267. (doi: 10.1080/1354750X.2016.1204003)

Pellicori, P., Carubelli, V. (2017) Terapia diuretica nell’insufficienza cardiaca cronica: evidenze, esperienze, prospettive = Diuretic treatment in patients with chronic heart failure: evidences, experiences, and current perspectives. Giornale Italiano di Cardiologia, 18, pp. 129-138. (doi: 10.1714/2663.27298)

Pellicori, P., Salekin, D., Pan, D., Clark, A. L. (2017) This patient is not breathing properly: is this COPD, heart failure, or neither? Expert Review of Cardiovascular Therapy, 15, pp. 389-396. (doi: 10.1080/14779072.2017.1317592)

2016

Torabi, A., Cleland, J. G.F., Sherwi, N., Atkin, P., Panahi, H., Kilpatrick, E., Thackray, S., Hoye, A., Alamgir, F., Goode, K., Rigby, A., Clark, A. L. (2016) Influence of case definition on incidence and outcome of acute coronary syndromes. Open Heart, 3, (doi: 10.1136/openhrt-2016-000487)

Teerlink, J. R., Felker, G. M., McMurray, J. J.V., Solomon, S. D., Adams, Jr., K. F., Cleland, J. G.F., Ezekowitz, J. A., Goudev, A., Macdonald, P., Metra, M., Mitrovic, V., Ponikowski, P., Serpytis, P., Spinar, J., Tomcsányi, J., Vandekerckhove, H. J., Voors, A. A., Monsalvo, M. L., Johnston, J., Malik, F. I., Honarpour, N. (2016) Chronic oral study of myosin activation to increase contractility in heart failure (COSMIC-HF): a phase 2, pharmacokinetic, randomised, placebo-controlled trial. Lancet, 388, pp. 2895-2903. (doi: 10.1016/S0140-6736(16)32049-9)

White, S. L., Lawlor, D. A., Briley, A. L., Godfrey, K. M., Nelson, S. M., Oteng-Ntim, E., Robson, S. C., Sattar, N., Seed, P. T., Vieira, M. C., Welsh, P., Whitworth, M., Poston, L., Pasupathy, D. (2016) Early antenatal prediction of gestational diabetes in obese women: development of prediction tools for targeted intervention. PLoS ONE, 11, (doi: 10.1371/journal.pone.0167846)

Vegter, E. L., Schmitter, D., Hagemeijer, Y., Ovchinnikova, E. S., van der Harst, P., Teerlink, J. R., O'Connor, C. M., Metra, M., Davison, B. A., Bloomfield, D., Cotter, G., Cleland, J. G.F., Givertz, M. M., Ponikowski, P., van Veldhuisen, D. J., van der Meer, P., Berezikov, E., Voors, A. A., Khan, M. A.F. (2016) Use of biomarkers to establish potential role and function of circulating microRNAs in acute heart failure. International Journal of Cardiology, 224, pp. 231-239. (doi: 10.1016/j.ijcard.2016.09.010)

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Loomis, A. K., Kabadi, S., Preiss, D., Hyde, C., Bonato, V., St. Louis, M., Desai, J., Gill, J. M.R., Welsh, P., Waterworth, D., Sattar, N. (2016) Body mass index and risk of non-alcoholic fatty liver disease: two electronic health record prospective studies. Journal of Clinical Endocrinology and Metabolism, 101, pp. 945-952. (doi: 10.1210/jc.2015-3444)

Mullan, A., Delles, C., Ferrell, W., Mullen, W., Edwards, C. A., McColl, J. H., Roberts, S. A., Lean, M. (2016) Effects of a beverage rich in (poly)phenols on established and novel risk markers for vascular disease in medically uncomplicated overweight or obese subjects: A four week randomized trial. Atherosclerosis, 246, pp. 169-176. (doi: 10.1016/j.atherosclerosis.2016.01.004)

Damman, K., Kjekshus, J., Wikstrand, J., Cleland, J. G.F., Komajda, M., Wedel, H., Waagstein, F., McMurray, J. J.V. (2016) Loop diuretics, renal function and clinical outcome in patients with heart failure and reduced ejection fraction. European Journal of Heart Failure, 18, pp. 328-336. (doi: 10.1002/ejhf.462)

Demissei, B. G., Valente, M. A.E., Cleland, J. G.F., O'Connor, C. M., Metra, M., Ponikowski, P., Teerlink, J. R., Cotter, G., Davison, B., Givertz, M. M., Bloomfield, D. M., Dittrich, H., van der Meer, P., van Veldhuisen, D. J., Hillege, H. L., Voors, A. A. (2016) Optimizing clinical use of biomarkers in high-risk acute heart failure patients. European Journal of Heart Failure, 18, pp. 269-280. (doi: 10.1002/ejhf.443)

Cuba Gyllensten, I., Bonomi, A. G., Goode, K. M., Reiter, H., Habetha, J., Amft, O., Cleland, J. G.F. (2016) Early indication of decompensated heart failure in patients on home-telemonitoring: a comparison of prediction algorithms based on daily weight and noninvasive transthoracic bio-impedance. JMIR Medical Informatics, 4, (doi: 10.2196/medinform.4842)

Demissei, B. G., Cleland, J. G.F., O'Connor, C. M., Metra, M., Ponikowski, P., Teerlink, J. R., Davison, B., Givertz, M. M., Bloomfield, D. M., Dittrich, H., van Veldhuisen, D. J., Hillege, H. L., Voors, A. A., Cotter, G. (2016) Procalcitonin-based indication of bacterial infection identifies high risk acute heart failure patients. International Journal of Cardiology, 204, pp. 164-171. (doi: 10.1016/j.ijcard.2015.11.141)

ter Maaten, J. M., Valente, M. A.E., Metra, M., Bruno, N., O’Connor, C. M., Ponikowski, P., Teerlink, J. R., Cotter, G., Davison, B., Cleland, J. G.F., Givertz, M. M., Bloomfield, D. M., Dittrich, H. C., van Veldhuisen, D. J., Hillege, H. L., Damman, K., Voors, A. A. (2016) A combined clinical and biomarker approach to predict diuretic response in acute heart failure. Clinical Research in Cardiology, 105, pp. 145-153. (doi: 10.1007/s00392-015-0896-2)

Currie, G., Delles, C., Touyz, R. M., Staessen, J. A., Dominiczak, A. F., Jennings, G. L. R., Wang, J.-G. (2016) A woman with treatment-resistant hypertension. Hypertension, 67, pp. 243-250. (doi: 10.1161/HYPERTENSIONAHA.115.06756)

Jones, F. E., Bailey, M. A., Murray, L. S., Lu, Y., McNeilly, S., Schlötzer-Schrehardt, U., Lennon, R., Sado, Y., Brownstein, D. G., Mullins, J. J., Kadler, K. E., Van Agtmael, T. (2016) ER stress and basement membrane defects combine to cause glomerular and tubular renal disease resulting from Col4a1 mutations in mice. Disease Models and Mechanisms, 9, pp. 165-76. (doi: 10.1242/dmm.021741)

Bhandari, S., Ives, N., Brettell, E. A., Valente, M., Cockwell, P., Topham, P. S., Cleland, J. G.F., Khwaja, A., El Nahas, M. (2016) Multicentre randomized controlled trial of angiotensin-converting enzyme inhibitor/angiotensin receptor blocker withdrawal in advanced renal disease: the STOP-ACEi trial. Nephrology Dialysis Transplantation, 31, pp. 255-261. (doi: 10.1093/ndt/gfv346)

Welsh, P., Hart, C., Papacosta, O., Preiss, D., McConnachie, A., Murray, H., Ramsay, S., Upton, M., Watt, G., Whincup, P., Wannamethee, G., Sattar, N. (2016) Prediction of cardiovascular disease risk by cardiac biomarkers in 2 United Kingdom cohort studies: does utility depend on risk thresholds for treatment? Hypertension, 2016, pp. 309-315. (doi: 10.1161/HYPERTENSIONAHA.115.06501)

Small, H. Y., Currie, G. E., Delles, C. (2016) Prostasin, proteases, and preeclampsia. Journal of Hypertension, 34, pp. 193-195. (doi: 10.1097/hjh.0000000000000828)

Carrick, D., Haig, C., Rauhalammi, S., Clerfond, G., Ahmed, N., Mordi, I., McEntegart, M., Petrie, M., Eteiba, H., Hood, S., Watkins, S., Lindsay, M. M., Mahrous, A., Welsh, P., Sattar, N., Ford, I., Oldroyd, K., Radjenovic, A., Berry, C. (2016) Temporal evolution of myocardial hemorrhage and edema in patients after acute ST-elevation myocardial infarction: pathophysiologic insights and clinical implications. Journal of the American Heart Association, 5, (doi: 10.1161/JAHA.115.002834)

Bruno, N., ter Maaten, J. M., Ovchinnikova, E. S., Vegter, E. L., Valente, M. A.E., van der Meer, P., de Boer, R. A., van der Harst, P., Schmitter, D., Metra, M., O'Connor, C. M., Ponikowski, P., Teerlink, J. R., Cotter, G., Davison, B., Cleland, J. G.F., Givertz, M. M., Bloomfield, D. M., Dittrich, H. C., Pinto, Y. M., van Veldhuisen, D. J., Hillege, H. L., Berezikov, E., Voors, A. A. (2016) MicroRNAs relate to early worsening of renal function in patients with acute heart failure. International Journal of Cardiology, 203, pp. 564-569. (doi: 10.1016/j.ijcard.2015.10.217)

Zhang, J., Hobkirk, J., Carroll, S., Pellicori, P., Clark, A. L., Cleland, J. G.F. (2016) Exploring quality of life in patients with and without heart failure. International Journal of Cardiology, 202, pp. 676-684. (doi: 10.1016/j.ijcard.2015.09.076)

Small, H. Y., Morgan, H., Beattie, E., Griffin, S., Indahl, M., Delles, C., Graham, D. (2016) Abnormal uterine artery remodelling in the stroke prone spontaneously hypertensive rat. Placenta, 37, pp. 34-44. (doi: 10.1016/j.placenta.2015.10.022)

Cowie, M. R., Bax, J., Bruining, N., Cleland, J. G.F., Koehler, F., Malik, M., Pinto, F., van der Velde, E., Vardas, P. (2016) e-Health: a position statement of the European Society of Cardiology. European Heart Journal, 37, pp. 63-66. (doi: 10.1093/eurheartj/ehv416)

Ponikowski, P., Voors, A. A., Anker, S. D., Bueno, H., Cleland, J. G.F., Coats, A. J.S., Falk, V., González-Juanatey, J. R., Harjola, V.-P., Jankowska, E. A., Jessup, M., Linde, C., Nihoyannopoulos, P., Parissis, J. T., Pieske, B., Riley, J. P., Rosano, G. M.C., Ruilope, L. M., Ruschitzka, F., Rutten, F. H., van der Meer, P., McMurray, J. J.V., Petrie, M. C. (2016) 2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure. European Heart Journal, 37, pp. 2129-2200. (doi: 10.1093/eurheartj/ehw128)

Olsen, M. H., Angell, S. Y., Asma, S., Boutouyrie, P., Burger, D., Chirinos, J. A., Damasceno, A., Delles, C., Gimenez-Roqueplo, A.-P., Hering, D., López-Jaramillo, P., Martinez, F., Perkovic, V., Rietzschel, E. R., Schillaci, G., Schutte, A. E., Scuteri, A., Sharman, J. E., Wachtell, K., Wang, J. G. (2016) A call to action and a lifecourse strategy to address the global burden of raised blood pressure on current and future generations: the Lancet Commission on hypertension. Lancet, 388, pp. 2665-2712. (doi: 10.1016/S0140-6736(16)31134-5)

Colman, M. A., Sarathy, P. P., MacQuiaide, N., Workman, A. J. (2016) A new model of the human atrial myocyte with variable T-tubule organization for the study of atrial fibrillation. Computing in Cardiology, 43, pp. 221-224. (doi: 10.23919/CIC.2016.7868719)

Boulberdaa, M., Scott, E., Ballantyne, M., Garcia, R., Descamps, B., Angelini, G. D., Brittan, M., Hunter, A., McBride, M., McClure, J., Miano, J. M., Emanueli, C., Mills, N. L., Mountford, J. C., Baker, A. H. (2016) A role for the long non-coding RNA SENCR in commitment and function of endothelial cells. Molecular Therapy, 24, pp. 978-990. (doi: 10.1038/mt.2016.41)

Rankin, N. J., Preiss, D., Welsh, P., Sattar, N. (2016) Applying metabolomics to cardiometabolic intervention studies and trials: past experiences and a roadmap for the future. International Journal of Epidemiology, 45, pp. 1351-1371. (doi: 10.1093/ije/dyw271)

Zhang, Z.-y., Ravassa, S., Yang, W.-Y., Petit, T., Pejchinovski, M., Zürbig, P., López, B., Wei, F.-F., Pontillo, C., Thijs, L., Jacobs, L., González, A., Koeck, T., Delles, C., Voigt, J.-U., Verhamme, P., Kuznetsova, T., Díez, J., Mischak, H., Staessen, J. A. (2016) Diastolic left ventricular function in relation to urinary and serum collagen biomarkers in a general population. PLoS ONE, 11, (doi: 10.1371/journal.pone.0167582)

McCallum, J. E., Mackenzie, A. E., Divorty, N., Clarke, C., Delles, C., Milligan, G., Nicklin, S. A. (2016) G protein-coupled receptor 35 mediates human saphenous vein vascular smooth muscle cell migration and endothelial cell proliferation. Journal of Vascular Research, 52, pp. 383-395. (doi: 10.1159/000444754)

Carrick, D., Haig, C., Watkins, S., Ahmed, N., McEntegart, M., Petrie, M. C., Eteiba, H., Hood, S., Watkins, S., Lindsay, M. M., Davie, A., Mahrous, A., Mordi, I., Rauhalammi, S., Sattar, N., Welsh, P., Radjenovic, A., Ford, I., Oldroyd, K., Berry, C. (2016) Myocardial hemorrhage after acute reperfused ST-segment-elevation myocardial infarction. Circulation: Cardiovascular Imaging, 9, (doi: 10.1161/CIRCIMAGING.115.004148)

Gillis, K. A., Mccomb, C., Patel, R. K., Stevens, K. K., Schneider, M. P., Radjenovic, A., Morris, S. T.W., Roditi, G. H., Delles, C., Mark, P. B. (2016) Non-contrast renal magnetic resonance imaging to assess perfusion and corticomedullary differentiation in health and chronic kidney disease. Nephron, 133, pp. 183-192. (doi: 10.1159/000447601)

Stoumpos, S., McNeill, S. H., Gorrie, M., Mark, P. B., Brennand, J. E., Geddes, C. C., Deighan, C. J. (2016) Obstetric and long-term kidney outcomes in renal transplant recipients: a 40 year single-centre study. Clinical Transplantation, 30, pp. 673-681. (doi: 10.1111/ctr.12732)

Lindhardt, M., Persson, F., Currie, G., Pontillo, C., Beige, J., Delles, C., von der Leyen, H., Mischak, H., Navis, G., Noutsou, M., Ortiz, A., Ruggenenti, P. L., Rychlik, I., Spasovski, G., Rossing, P. (2016) Proteomic prediction and Renin angiotensin aldosterone system Inhibition prevention Of early diabetic nephRopathy in TYpe 2 diabetic patients with normoalbuminuria (PRIORITY): essential study design and rationale of a randomised clinical multicentre trial. BMJ Open, 6, (doi: 10.1136/bmjopen-2015-010310)

Sheikh, A. M., Small, H. Y., Currie, G., Delles, C. (2016) Systematic review of micro-RNA expression in pre-eclampsia identifies a number of common pathways associated with the disease. PLoS ONE, 11, (doi: 10.1371/journal.pone.0160808)

Jackson, C. E., Haig, C., Welsh, P., Dalzell, J. R., Tsorlalis, I. K., McConnachie, A., Preiss, D., Anker, S. D., Sattar, N., Petrie, M. C., Gardner, R. S., McMurray, J. J. V. (2016) The incremental prognostic and clinical value of multiple novel biomarkers in heart failure. European Journal of Heart Failure, 18, pp. 1491-1498. (doi: 10.1002/ejhf.543)

Emdin, C. A., Conrad, N., Kiran, A., Salimi-Khorshidi, G., Woodward, M., Anderson, S. G., Mohseni, H., Dargie, H. J., Hardman, S. M.C., McDonagh, T., McMurray, J. J.V., Cleland, J. G.F., Rahimi, K. (2016) Variation in hospital performance for heart failure management in the National Heart Failure Audit for England and Wales. Heart, 103, pp. 55-62. (doi: 10.1136/heartjnl-2016-309706)

Rutherford, E., Mark, P. (2016) What does STOP-IgAN tell us about how to treat IgA nephropathy? Journal of the Royal College of Physicians of Edinburgh, 46, pp. 23-25. (doi: 10.4997/JRCPE.2016.107)

2015

Cameron, A. C., Touyz, R. M., Lang, N. N. (2015) Vascular complications of cancer chemotherapy. Canadian Journal of Cardiology, 32, pp. 852-862. (doi: 10.1016/j.cjca.2015.12.023)

Cleland, J. G.F., Mareev, Y. (2015) CRT for heart failure and ESRD: more trials or more thought needed? Journal of the American College of Cardiology, 66, pp. 2630-2632. (doi: 10.1016/j.jacc.2015.10.022)

Solbu, M. D., Thomson, P. C., Macpherson, S., Findlay, M. D., Stevens, K. K., Patel, R. K., Padmanabhan, S., Jardine, A. G., Mark, P. B. (2015) Serum phosphate and social deprivation independently predict all-cause mortality in chronic kidney disease. BMC Nephrology, 16, (doi: 10.1186/s12882-015-0187-1)

Jolicœur, E. M., Dunning, A., Castelvecchio, S., Dabrowski, R., Waclawiw, M. A., Petrie, M. C., Stewart, R., Jhund, P. S., Desvigne-Nickens, P., Panza, J. A., Bonow, R. O., Sun, B., San, T. R., Al-Khalidi, H. R., Rouleau, J. L., Velazquez, E. J., Cleland, J. G.F. (2015) Importance of angina in patients with coronary disease, heart failure, and left ventricular systolic dysfunction. Journal of the American College of Cardiology, 66, pp. 2092-2100. (doi: 10.1016/j.jacc.2015.08.882)

Pellicori, P., Joseph, A. C., Zhang, J., Lukaschuk, E., Sherwi, N., Bourantas, C. V., Loh, H., Clark, A. L., Cleland, J. G.F. (2015) The relationship of QRS morphology with cardiac structure and function in patients with heart failure. Clinical Research in Cardiology, 104, pp. 935-945. (doi: 10.1007/s00392-015-0861-0)

Inglis, S. C., Clark, R. A., Dierckx, R., Prieto-Merino, D., Cleland, J. G.F. (2015) Structured telephone support or non-invasive telemonitoring for patients with heart failure. Cochrane Database of Systematic Reviews, 2015, (doi: 10.1002/14651858.CD007228.pub3)

Deng, L., Blanco Lopez, F. J., Stevens, H., Lu, R., Caudrillier, A., McBride, M., McClure, J. D., Grant, J., Thomas, M., Frid, M., Stenmark, K., White, K., Seto, A. G., Morrell, N. W., Bradshaw, A. C., MacLean, M. R., Baker, A. H. (2015) MicroRNA-143 activation regulates smooth muscle and endothelial cell crosstalk in pulmonary arterial hypertension. Circulation Research, 117, pp. 870-883. (doi: 10.1161/CIRCRESAHA.115.306806)

Farag, M., Mabote, T., Shoaib, A., Zhang, J., Nabhan, A. F., Clark, A. L., Cleland, J. G. (2015) Hydralazine and nitrates alone or combined for the management of chronic heart failure: a systematic review. International Journal of Cardiology, 196, pp. 61-69. (doi: 10.1016/j.ijcard.2015.05.160)

Mareev, Y., Cleland, J. G.F. (2015) Should β-blockers be used in patients with heart failure and atrial fibrillation? Clinical Therapeutics, 37, pp. 2215-2224. (doi: 10.1016/j.clinthera.2015.08.017)

Shadman, R., Poole, J. E., Dardas, T. F., Mozaffarian, D., Cleland, J. G.F., Swedberg, K., Maggioni, A. P., Anand, I. S., Carson, P. E., Miller, A. B., Levy, W. C. (2015) A novel method to predict the proportional risk of sudden cardiac death in heart failure: derivation of the Seattle Proportional Risk Model. Heart Rhythm, 12, pp. 2069-2077. (doi: 10.1016/j.hrthm.2015.06.039)

Patel, R., Jeemon, P., Stevens, K., Mccallum, L., Hastie, C., Schneider, A., Jardine, A., Mark, P., Padmanabhan, S. (2015) Association between serum phosphate and calcium, long-term blood pressure, and mortality in treated hypertensive adults. Journal of Hypertension, 33, pp. 2046-2053. (doi: 10.1097/hjh.0000000000000659)

Butcher, C., Mareev, Y., Markides, V., Mason, M., Wong, T., Cleland, J.G.F. (2015) Cardiac resynchronization therapy update: evolving indications, expanding benefit? Current Cardiology Reports, 17, (doi: 10.1007/s11886-015-0641-5)

Akehurst, C., Small, H., Sharafetdinova, L., Forrest, R., Beattie, W., Brown, C. E., Robinson, S. W., McClure, J. D., Work, L. M., Carty, D. M., McBride, M. W., Freeman, D. J., Delles, C. (2015) Differential expression of microRNA-206 and its target genes in pre-eclampsia. Journal of Hypertension, 33, pp. 2068-2074. (doi: 10.1097/HJH.0000000000000656)

Frankenstein, L., Fröhlich, H., Cleland, J. G.F. (2015) Multidisciplinary approach for patients hospitalized with heart failure. Revista Española de Cardiología (English Edition), 68, pp. 885-891. (doi: 10.1016/j.rec.2015.05.008)

Zoccarato, A. et al. (2015) Cardiac hypertrophy is inhibited by a local pool of cAMP regulated by phosphodiesterase 2. Circulation Research, 117, pp. 707-719. (doi: 10.1161/CIRCRESAHA.114.305892)

Cleland, J. G.F., Freemantle, N. (2015) QRS morphology as a predictor of the response to cardiac resynchronisation therapy: fact or fashion? Heart, 101, pp. 1441-1443. (doi: 10.1136/heartjnl-2015-307553)

Wannamethee, S. G., Welsh, P., Papacosta, O., Lennon, L., Whincup, P. H., Sattar, N. (2015) Copeptin, insulin resistance, and risk of incident diabetes in older men. Journal of Clinical Endocrinology and Metabolism, 100, pp. 3332-3339. (doi: 10.1210/JC.2015-2362)

Lindsey, M. L., Mayr, M., Gomes, A. V., Delles, C., Arrell, D. K., Murphy, A. M., Lange, R. A., Costello, C. E., Jin, Y.-F., Laskowitz, D. T., Sam, F., Terzic, A., Van Eyk, J., Srinivas, P. R. (2015) Transformative impact of proteomics on cardiovascular health and disease: a scientific statement from the American Heart Association. Circulation, 132, pp. 852-872. (doi: 10.1161/CIR.0000000000000226)

Pellicori, P., Clark, A. L. (2015) Clinical trials update from the European Society of Cardiology-Heart Failure meeting 2015: AUGMENT-HF, TITRATION, STOP-HF, HARMONIZE, LION HEART, MOOD-HF, and renin-angiotensin inhibitors in patients with heart and renal failure. European Journal of Heart Failure, 17, pp. 979-983. (doi: 10.1002/ejhf.340)

Damy, T., Hobkirk, J., Walters, M., Ciobanu, A., Rigby, A. S., Kallvikbacka-Bennett, A., Guellich, A., Dubois-Randé, J.-L., Hittinger, L., Clark, A. L., Cleland, J. G.F. (2015) Development of a human model for the study of effects of hypoxia, exercise, and sildenafil on cardiac and vascular function in chronic heart failure. Journal of Cardiovascular Pharmacology, 66, pp. 229-238. (doi: 10.1097/FJC.0000000000000262)

Dierckx, R., Cleland, J. G.F., Pellicori, P., Zhang, J., Goode, K., Putzu, P., Boyalla, V., Clark, A. L. (2015) If home telemonitoring reduces mortality in heart failure, is this just due to better guideline-based treatment? Journal of Telemedicine and Telecare, 21, pp. 331-339. (doi: 10.1177/1357633X15574947)

Findlay, M. D., Thomson, P. C., Fulton, R. L., Solbu, M. D., Jardine, A. G., Patel, R. K., Stevens, K. K., Geddes, C. C., Dawson, J., Mark, P. B. (2015) Risk factors of ischemic stroke and subsequent outcome in hemodialysis patients. Stroke, 46, pp. 2477-2481. (doi: 10.1161/STROKEAHA.115.009095)

Stut, W., Deighan, C., Cleland, J. G., Jaarsma, T. (2015) Adherence to self-care in patients with heart failure in the HeartCycle study. Patient Preference and Adherence, 9, pp. 1195-1206. (doi: 10.2147/PPA.S88482)

Lees, J. S., Mark, P. B., Jardine, A. G. (2015) Cardiovascular complications of chronic kidney disease. Medicine, 43, pp. 469-473. (doi: 10.1016/j.mpmed.2015.05.009)

Jackson, C. E., Haig, C., Welsh, P., Dalzell, J. R., Tsorlalis, I. K., McConnachie, A., Preiss, D., McInnes, I. B., Sattar, N., Petrie, M. C., Gardner, R. S., McMurray, J. J.V. (2015) Combined free light chains are novel predictors of prognosis in heart failure. JACC: Heart Failure, 3, pp. 618-625. (doi: 10.1016/j.jchf.2015.03.014)

Schanstra, J.P. et al. (2015) Diagnosis and prediction of CKD progression by assessment of urinary peptides. Journal of the American Society of Nephrology, 26, pp. 1999-2010. (doi: 10.1681/asn.2014050423)

Mann, J. F.E., Rossing, P., Wiȩcek, A., Rosivall, L., Mark, P., Mayer, G. (2015) Diagnosis and treatment of early renal disease in patients with type 2 diabetes mellitus: what are the clinical needs? Nephrology Dialysis Transplantation, 30, pp. iv1-iv5. (doi: 10.1093/ndt/gfv120)

Menni, C. et al. (2015) Metabolomic identification of a novel pathway of blood pressure regulation involving hexadecanedioate. Hypertension, 66, pp. 422-429. (doi: 10.1161/HYPERTENSIONAHA.115.05544)

Cleland, J. G.F., Mareev, Y., Linde, C. (2015) Reflections on EchoCRT: sound guidance on QRS duration and morphology for CRT? European Heart Journal, 36, pp. 1948-1951. (doi: 10.1093/eurheartj/ehv264)

Askevold, E. T., Gullestad, L., Nymo, S., Kjekshus, J., Yndestad, A., Latini, R., Cleland, J. G.F., McMurray, J. J.V., Aukrust, P., Ueland, T. (2015) Secreted frizzled related protein 3 in chronic heart failure: analysis from the controlled rosuvastatin multinational trial in heart failure (CORONA) PLoS ONE, 10, (doi: 10.1371/journal.pone.0133970)

Raphael, C. E., Finegold, J. A., Barron, A. J., Whinnett, Z. I., Mayet, J., Linde, C., Cleland, J. G.F., Levy, W. C., Francis, D. P. (2015) The effect of duration of follow-up and presence of competing risk on lifespan-gain from implantable cardioverter defibrillator therapy: who benefits the most? European Heart Journal, 36, pp. 1676-1688. (doi: 10.1093/eurheartj/ehv102)

Mentz, R. J., Metra, M., Cotter, G., Milo, O., McKendry, C., Chiswell, K., Davison, B. A., Cleland, J. G.F., Bloomfield, D. M., Dittrich, H. C., Fiuzat, M., Ponikowski, P., Givertz, M. M., Voors, A. A., Teerlink, J. R., O'Connor, C. M. (2015) Early vs. late worsening heart failure during acute heart failure hospitalization: insights from the PROTECT trial. European Journal of Heart Failure, 17, pp. 697-706. (doi: 10.1002/ejhf.308)

Ferrari, R., Böhm, M., Cleland, J. G.F., Paulus, W. J.S., Pieske, B., Rapezzi, C., Tavazzi, L. (2015) Heart failure with preserved ejection fraction: uncertainties and dilemmas. European Journal of Heart Failure, 17, pp. 665-671. (doi: 10.1002/ejhf.304)

Carrick, D., Haig, C., Rauhalammi, S., Ahmed, N., Mordi, I., McEntegart, M., Petrie, M., Eteiba, H., Lindsay, M., Watkins, S., Hood, S., Davie, A., Marous, A., Sattar, N., Welsh, P., Tzemos, N., Radjenovic, A., Ford, I., Oldroyd, K., Berry, C. (2015) Pathophysiology of LV remodeling in survivors of STEMI : inflammation, remote myocardium, and prognosis. JACC: Cardiovascular Imaging, 8, pp. 779-789. (doi: 10.1016/j.jcmg.2015.03.007)

Pellicori, P., Kallvikbacka-Bennett, A., Dierckx, R., Zhang, J., Putzu, P., Cuthbert, J., Boyalla, V., Shoaib, A., Clark, A. L., Cleland, J. G.F. (2015) Prognostic significance of ultrasound-assessed jugular vein distensibility in heart failure. Heart, 101, pp. 1149-1158. (doi: 10.1136/heartjnl-2015-307558)

Zannad, F., Greenberg, B., Cleland, J. G.F., Gheorghiade, M., van Veldhuisen, D. J., Mehra, M. R., Anker, S. D., Byra, W. M., Fu, M., Mills, R. M. (2015) Rationale and design of a randomized, double-blind, event-driven, multicentre study comparing the efficacy and safety of oral rivaroxaban with placebo for reducing the risk of death, myocardial infarction or stroke in subjects with heart failure and significant coronary artery disease following an exacerbation of heart failure: the COMMANDER HF trial. European Journal of Heart Failure, 17, pp. 735-742. (doi: 10.1002/ejhf.266)

McDonald, R. A., Halliday, C. A., Miller, A. M., Diver, L. A., Dakin, R. S., Montgomery, J., McBride, M. W., Kennedy, S., McClure, J. D., Robertson, K. E., Douglas, G., Channon, K. M., Oldroyd, K., Baker, A. H. (2015) Reducing in-stent restenosis therapeutic manipulation of miRNA in vascular remodeling and inflammation. Journal of the American College of Cardiology, 65, pp. 2314-2327. (doi: 10.1016/j.jacc.2015.03.549)

Inglis, S. C., Conway, A., Cleland, J. G.F., Clark, R. A. (2015) Is age a factor in the success or failure of remote monitoring in heart failure? Telemonitoring and structured telephone support in elderly heart failure patients. European Journal of Cardiovascular Nursing, 14, pp. 248-255. (doi: 10.1177/1474515114530611)

Kristensen, S. L., Jhund, P. S., Køber, L., McKelvie, R. S., Zile, M. R., Anand, I. S., Komajda, M., Cleland, J. G.F., Carson, P. E., McMurray, J. J.V. (2015) Relative importance of history of heart failure hospitalization and N-terminal pro–B-type natriuretic peptide level as predictors of outcomes in patients with heart failure and preserved ejection fraction. JACC: Heart Failure, 3, pp. 478-486. (doi: 10.1016/j.jchf.2015.01.014)

Dakin, R. S., Parker, A. L., Delles, C., Nicklin, S. A., Baker, A. H. (2015) Efficient transduction of primary vascular cells by the rare adenovirus serotype 49 vector. Human Gene Therapy, 26, pp. 312-319. (doi: 10.1089/hum.2015.019)

Fox, C. S., Hall, J. L., Arnett, D. K., Ashley, E. A., Delles, C., Engler, M. B., Freeman, M. W., Johnson, J. A., Lanfear, D. E., Liggett, S. B., Lusis, A. J., Loscalzo, J., MacRae, C. A., Musunuru, K., Newby, L. K., O'Donnell, C. J., Rich, S. S., Terzic, A. (2015) Future translational applications from the contemporary genomics era: a scientific statement from the American Heart Association. Circulation, 131, pp. 1715-1736. (doi: 10.1161/CIR.0000000000000211)

Costanzo, P., Cleland, J. G.F., Pellicori, P., Clark, A. L., Hepburn, D., Kilpatrick, E. S., Perrone-Filardi, P., Zhang, J., Atkin, S. L. (2015) The obesity paradox in type 2 diabetes mellitus: relationship of body mass index to prognosis: a cohort study. Annals of Internal Medicine, 162, pp. 610-618. (doi: 10.7326/M14-1551)

Rutherford, M.A., Rankin, A.J., Yates, T.M., Mark, P.B., Perry, C.G., Reed, N.S., Freel, E.M. (2015) Management of metastatic phaeochromocytoma and paraganglioma: use of Iodine-131-meta-iodobenzylguanidine (131I-MIBG) therapy in a tertiary referral centre. QJM: An International Journal of Medicine, 108, pp. 361-368. (doi: 10.1093/qjmed/hcu208)

Filippatos, G., Khan, S. S., Ambrosy, A. P., Cleland, J. G.F., Collins, S. P., Lam, C. S.P., Angermann, C. E., Ertl, G., Dahlström, U., Hu, D., Dickstein, K., Perrone, S. V., Ghadanfar, M., Bermann, G., Noe, A., Schweizer, A., Maier, T., Gheorghiade, M. (2015) International REgistry to assess medical practice with lOngitudinal obseRvation for Treatment of Heart Failure (REPORT-HF): rationale for and design of a global registry. European Journal of Heart Failure, 17, pp. 527-533. (doi: 10.1002/ejhf.262)

Davison, B. A., Metra, M., Cotter, G., Massie, B. M., Cleland, J. G.F., Dittrich, H. C., Edwards, C., Filippatos, G., Givertz, M. M., Greenberg, B., Ponikowski, P., Voors, A. A., O’Connor, C. M., Teerlink, J. R. (2015) Worsening heart failure following admission for acute heart failure: a pooled analysis of the PROTECT and RELAX-AHF studies. JACC: Heart Failure, 3, pp. 395-403. (doi: 10.1016/j.jchf.2015.01.007)

Ravassa, S., Kuznetsova, T., Varo, N., Thijs, L., Delles, C., Dominiczak, A., Díez, J., Staessen, J. A. (2015) Biomarkers of cardiomyocyte injury and stress identify left atrial and left ventricular remodelling and dysfunction: a population-based study. International Journal of Cardiology, 185, pp. 177-185. (doi: 10.1016/j.ijcard.2015.03.046)

Rousset, C. I., Leiper, F. C., Kichev, A., Gressens, P., Carling, D., Hagberg, H., Thornton, C. (2015) A dual role for AMP-activated protein kinase (AMPK) during neonatal hypoxic-ischaemic brain injury in mice. Journal of Neurochemistry, 133, pp. 242-252. (doi: 10.1111/jnc.13034)

McInnes, I. B., Thompson, L., Giles, J. T., Bathon, J. M., Salmon, J. E., Beaulieu, A. D., Codding, C. E., Carlson, T. H., Delles, C., Lee, J. S., Sattar, N. (2015) Effect of interleukin-6 receptor blockade on surrogates of vascular risk in rheumatoid arthritis: MEASURE, a randomised, placebo-controlled study. Annals of the Rheumatic Diseases, 74, pp. 694-702. (doi: 10.1136/annrheumdis-2013-204345)

Mischak, H., Delles, C., Vlahou, A., Vanholder, R. (2015) Proteomic biomarkers in kidney disease: issues in development and implementation. Nature Reviews Nephrology, 11, pp. 221-232. (doi: 10.1038/nrneph.2014.247)

Cleland, J. G.F., Butcher, C. (2015) When is it appropriate to withdraw cardiac resynchronization therapy? Guesses and evidence. JACC: Heart Failure, 3, pp. 337-339. (doi: 10.1016/j.jchf.2015.01.003)

Pellicori, P., Zhang, J., Lukaschuk, E., Joseph, A. C., Bourantas, C. V., Loh, H., Bragadeesh, T., Clark, A. L., Cleland, J. G.F. (2015) Left atrial function measured by cardiac magnetic resonance imaging in patients with heart failure: clinical associations and prognostic value. European Heart Journal, 36, pp. 733-742. (doi: 10.1093/eurheartj/ehu405)

Rannikmäe, K. et al. (2015) Common variation in COL4A1/COL4A2 is associated with sporadic cerebral small vessel disease. Neurology, 84, pp. 918-926. (doi: 10.1212/WNL.0000000000001309)

Jankowska, E. A., Wojtas, K., Kasztura, M., Mazur, G., Butrym, A., Kalicinska, E., Rybinska, I., Skiba, J., von Haehling, S., Doehner, W., Anker, S. D., Banasiak, W., Cleland, J. G.F., Ponikowski, P. (2015) Bone marrow iron depletion is common in patients with coronary artery disease. International Journal of Cardiology, 182, pp. 517-522. (doi: 10.1016/j.ijcard.2014.10.006)

Metra, M., Cotter, G., El-Khorazaty, J., Davison, B. A., Milo, O., Carubelli, V., Bourge, R. C., Cleland, J. G., Jondeau, G., Krum, H., O'Connor, C. M., Parker, J. D., Torre-Amione, G., van Veldhuisen, D. J., Rainisio, M., Kobrin, I., McMurray, J. J., Teerlink, J. R. (2015) Acute heart failure in the elderly: differences in clinical characteristics, outcomes, and prognostic factors in the VERITAS Study. Journal of Cardiac Failure, 21, pp. 179-88. (doi: 10.1016/j.cardfail.2014.12.012)

Skogstrand, T., Leh, S., McClure, J., Dashti, M., Iversen, B. M., Graham, D., McBride, M., Hultström, M. (2015) Identification of a common molecular pathway in hypertensive renal damage. Journal of Hypertension, 33, pp. 584-596. (doi: 10.1097/HJH.0000000000000395)

Pellicori, P., Cleland, J. G.F. (2015) Is the epidemic of heart disease really over or just evolving? American Journal of Medicine, 128, pp. e17. (doi: 10.1016/j.amjmed.2014.09.018)

Dierckx, R., Cleland, J. G.F., Parsons, S., Putzu, P., Pellicori, P., Dicken, B., Boyalla, V., Clark, A. L. (2015) Prescribing patterns to optimize heart rate: analysis of 1,000 consecutive outpatient appointments to a single heart failure clinic over a 6-month period. JACC: Heart Failure, 3, pp. 224-230. (doi: 10.1016/j.jchf.2014.11.003)

Khand, A. U., Chew, P. G., Douglas, H., Jones, J., Jan, A., Cleland, J.G.F. (2015) The effect of carvedilol on b-type natriuretic peptide and cardiac function in patients with heart failure and persistent atrial fibrillation. Cardiology, 130, pp. 153-158. (doi: 10.1159/000368746)

Pellicori, P., Cleland, J. G.F. (2015) Update on management of heart failure with preserved ejection fraction. Current Opinion in Cardiology, 30, pp. 173-178. (doi: 10.1097/HCO.0000000000000152)

Kristensen, S. L., Jhund, P. S., Køber, L., Preiss, D., Kjekshus, J., McKelvie, R. S., Zile, M. R., Anand, I. S., Wikstrand, J. G.F., Wedel, H., Komajda, M., Carson, P. E., Cleland, J., McMurray, J. J.V. (2015) Comparison of outcomes after hospitalization for worsening heart failure, myocardial infarction, and stroke in patients with heart failure and reduced and preserved ejection fraction. European Journal of Heart Failure, 17, pp. 169-176. (doi: 10.1002/ejhf.211)

Boyalla, V., Putzu, P., Dierckx, R., Clark, A. L., Pellicori, P. (2015) Patent Ductus Arteriosus in older adults: incidental finding or relevant pathology? Journal of the American Geriatrics Society, 63, pp. 409-411. (doi: 10.1111/jgs.13256)

Alday, E. A. P., Colman, M. A., Langley, P., Butters, T. D., Higham, J., Workman, A. J., Hancox, J. C., Zhang, H. (2015) A new algorithm to diagnose atrial ectopic origin from multi lead ECG systems: insights from 3D virtual human atria and torso. PLoS Computational Biology, 11, pp. e1004026. (doi: 10.1371/journal.pcbi.1004026)

Metra, M., Mentz, R. J., Chiswell, K., Bloomfield, D. M., Cleland, J. G.F., Cotter, G., Davison, B. A., Dittrich, H. C., Fiuzat, M., Givertz, M. M., Lazzarini, V., Mansoor, G. A., Massie, B. M., Ponikowski, P., Teerlink, J. R., Voors, A. A., O'Connor, C. M. (2015) Acute heart failure in elderly patients: worse outcomes and differential utility of standard prognostic variables. Insights from the PROTECT trial. European Journal of Heart Failure, 17, pp. 109-118. (doi: 10.1002/ejhf.207)

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Dickstein, K., Normand, C., Anker, S.D., Auricchio, A., Lundqvist Blomstrom, C., Bogale, N., Cleland, J., Filippatos, G., Gasparini, M., Gitt, A., Hindricks, G., Kuck, K.-H., Ponikowski, P., Stellbrink, C., Ruschitzka, F., Linde, C. (2015) European cardiac resynchronization therapy survey II: rationale and design. Europace, 17, pp. 137-141. (doi: 10.1093/europace/euu312)

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Dierckx, R., Pellicori, P., Cleland, J.G.F., Clark, A.L. (2015) Telemonitoring in heart failure: Big Brother watching over you. Heart Failure Reviews, 20, pp. 107-116. (doi: 10.1007/s10741-014-9449-4)

Musunuru, K., Hickey, K. T., Al-Khatib, S. M., Delles, C., Fornage, M., Fox, C. S., Frazier, L., Gelb, B. D., Herrington, D. M., Lanfear, D. E., Rosand, J. (2015) Basic concepts and potential applications of genetics and genomics for cardiovascular and stroke clinicians: a scientific statement from the American Heart Association. Circulation: Cardiovascular Genetics, 8, pp. 216-242. (doi: 10.1161/HCG.0000000000000020)

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Welsh, P., Preiss, D., Touyz, R. M. (2015) Biomarkers of hypertension and cardiovascular disease. Royal Society of Chemistry

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Pellicori, P., Kaur, K., Clark, A. L. (2015) Fluid management in patients with chronic heart failure. Cardiac Failure Review, 1, pp. 90-95. (doi: 10.15420/cfr.2015.1.2.90)

Lopez, L. M., Hill, W. D., Harris, S. E., Valdes Hernandez, M., Munoz Maniega, S., Bastin, M. E., Bailey, E., Smith, C., McBride, M., McClure, J., Graham, D., Dominiczak, A., Yang, Q., Fornage, M., Ikram, M. A., Debette, S., Launer, L., Bis, J. C., Schmidt, R., Seshadri, S., Porteous, D. J., Starr, J., Deary, I. J., Wardlaw, J. M. (2015) Genes from a translational analysis support a multifactorial nature of white matter hyperintensities. Stroke, 46, pp. 341-347. (doi: 10.1161/STROKEAHA.114.007649)

Mistry, H.D., Eisele, N., Escher, G., Dick, B., Surbek, D., Delles, C., Currie, G., Schlembach, D., Mohaupt, M.G., Gennari-Moser, C. (2015) Gestation-specific reference intervals for comprehensive spot urinary steroid hormone metabolite analysis in normal singleton pregnancy and 6 weeks postpartum. Reproductive Biology and Endocrinology, 13, (doi: 10.1186/s12958-015-0100-6)

Sattar, N., Welsh, P., Preiss, D. (2015) The insulin resistance syndrome. John Wiley & Sons, Ltd

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PGR Students

Qiaoling Liu 

  • Postgraduate Research Student 
  • Research title: Physical Activity and Its Association with CVD

The kidney theme is led by clinical academic nephrologists (kidney specialists) working in tandem with NHS colleagues working at the Glasgow Renal and Transplant Unit at the Queen Elizabeth University Hospital, Glasgow as well as wider collaborations with academics across the MVLS college.

Chronic kidney disease leads to premature death, and we focus on better understanding and treating the leading causes of death of people with kidney disease, namely cardiovascular disease and cancer. To achieve these aims.

  • We use epidemiological (‘big data’) research to understand why people with kidney disease are at higher risk of these conditions and address what can be done to reduce this risk.
  • We undertake clinical trials to assess what are the best treatments to improve survival and reduce the risk of cardiovascular disease for people with kidney disease.
  • We work closely with our Kidney Patient and Public Involvement and Engagement group to guide our research aims and to improve dissemination and impact.
  • We collaborate widely with researchers at the University of Glasgow, across the United Kingdom, and internationally, working with academics, NHS clinicians and the pharmaceutical industry.

The impacts of our work will improve the health of people with or at risk of kidney disease.