Dr Peter Moult

  • Lecturer (Psychology & Neuroscience Education Hub)

telephone: 01413304545
email: Peter.Moult@glasgow.ac.uk

School of Life Sciences, College of Medical, Veterinary & Life Sciences, 341, Sir James Black Building, University of Glasgow, G12 8QQ

Import to contacts

Research interests

My research background is in synaptic plasticity, neuromodulation, neuromuscular ageing and locomotor network modulation. The nervous system is made up of billions of nerve cells (neurons) making up complex networks and pathways that control almost every function in every part of the body. Contrary to the classical text book picture of neurons and neural networks, they are highly dynamic, highly plastic and undergo both structural and biochemical changes during both their physiological and pathophysiological processes. My research to date has focused on understanding the cellular mechanisms of such changes in order to better understand neuronal and network function.  This understanding has applications to spinal cord injury, neuromuscular ageing, learning and memory and neurodegenerative disorders. My most recent work involved using a range of techniques including neuronal cell culture, electrophysiology, immunocytochemistry, and atomic force microscopy to investigate both the mechanisms of modulation of spinal cord neurons and networks and how these changes affect locomotor output. I also have ongoing projects investigating neuromuscular ageing and plasticity of the neuromuscular junction – the interface between the nervous system and skeletomuscular system.

Publications

List by: Type | Date

Jump to: 2018 | 2017 | 2015 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2006 | 2004 | 2002
Number of items: 16.

2018

Sidlauskaite, E., Gibson, J. W., Megson, I. L., Whitfield, P. D., Tovmasyan, A., Batinic-Haberle, I., Murphy, M. P., Moult, P. R. and Cobley, J. N. (2018) Mitochondrial ROS cause motor deficits induced by synaptic inactivity: implications for synapse pruning. Redox Biology, 16, pp. 344-351. (doi: 10.1016/j.redox.2018.03.012) (PMID:29587245) (PMCID:PMC5953219)

2017

Kankia, I. H., Khalil, H. S., Langdon, S. P., Moult, P. R., Bown, J. L. and Deeni, Y. Y. (2017) NRF2 regulates HER1 signaling pathway to modulate the sensitivity of ovarian cancer cells to lapatinib and erlotinib. Oxidative Medicine and Cellular Longevity, 2017, 1864578. (doi: 10.1155/2017/1864578) (PMID:29410730) (PMCID:PMC5749283)

2015

Cobley, J. N., Moult, P. R., Burniston, J. G., Morton, J. P. and Close, G. L. (2015) Exercise improves mitochondrial and redox-regulated stress responses in the elderly: better late than never! Biogerontology, 16(2), pp. 249-264. (doi: 10.1007/s10522-014-9546-8) (PMID:25537184)

2013

Moult, P. R., Cottrell, G. A. and Li, W.-C. (2013) Fast silencing reveals a lost role for reciprocal inhibition in locomotion. Neuron, 77(1), pp. 129-140. (doi: 10.1016/j.neuron.2012.10.040) (PMID:23312521) (PMCID:PMC3542422)

2012

Li, W.-C. and Moult, P. R. (2012) The control of locomotor frequency by excitation and inhibition. Journal of Neuroscience, 32(18), pp. 6220-6230. (doi: 10.1523/JNEUROSCI.6289-11.2012) (PMID:22553028) (PMCID:PMC3351984)

2011

Moult, P. R. and Harvey, J. (2011) NMDA receptor subunit composition determines the polarity of leptin-induced synaptic plasticity. Neuropharmacology, 61(5-6), pp. 924-936. (doi: 10.1016/j.neuropharm.2011.06.021) (PMID:21752339) (PMCID:PMC3300059)

2010

Moult, P. R., Cross, A., Santos, S. D., Carvalho, A.-L., Lindsay, Y., Connolly, C. N., Irving, A. J., Leslie, N. R. and Harvey, J. (2010) Leptin regulates AMPA receptor trafficking via PTEN inhibition. Journal of Neuroscience, 30(11), pp. 4088-4101. (doi: 10.1523/JNEUROSCI.3614-09.2010) (PMID:20237279) (PMCID:PMC2843829)

2009

Moult, P. R. (2009) Neuronal glutamate and GABAA receptor function in health and disease. Biochemical Society Transactions, 37(6), pp. 1317-1322. (doi: 10.1042/BST0371317) (PMID:19909268)

Moult, P. R. and Harvey, J. (2009) Regulation of glutamate receptor trafficking by leptin. Biochemical Society Transactions, 37(6), pp. 1364-1368. (doi: 10.1042/BST0371364) (PMID:19909277) (PMCID:PMC2808539)

Moult, P. R., Milojkovic, B. and Harvey, J. (2009) Leptin reverses long-term potentiation at hippocampal CA1 synapses. Journal of Neurochemistry, 108(3), pp. 685-696. (doi: 10.1111/j.1471-4159.2008.05810.x) (PMID:19054283) (PMCID:PMC2638023)

Solovyova, N., Moult, P. R., Milojkovic, B., Lambert, J. J. and Harvey, J. (2009) Bi-directional modulation of fast inhibitory synaptic transmission by leptin. Journal of Neurochemistry, 108(1), pp. 190-201. (doi: 10.1111/j.1471-4159.2008.05751.x) (PMID:19094063) (PMCID:PMC2605943)

2008

Moult, P. R., Corrêa, S. A.L., Collingridge, G. L., Fitzjohn, S. M. and Bashir, Z. I. (2008) Co-activation of p38 mitogen-activated protein kinase and protein tyrosine phosphatase underlies metabotropic glutamate receptor-dependent long-term depression. Journal of Physiology, 586(10), pp. 2499-2510. (doi: 10.1113/jphysiol.2008.153122) (PMID:18356198)

Moult, P. R. and Harvey, J. (2008) Hormonal regulation of hippocampal dendritic morphology and synaptic plasticity. Cell Adhesion and Migration, 2(4), pp. 269-275. (doi: 10.4161/cam.2.4.6354) (PMID:19262152) (PMCID:PMC2633690)

2006

Moult, P. R., Gladding, C. M., Sanderson, T. M., Fitzjohn, S. M., Bashir, Z. I., Molnar, E. and Collingridge, G. L. (2006) Tyrosine phosphatases regulate AMPA receptor trafficking during metabotropic glutamate receptor-mediated long-term depression. Journal of Neuroscience, 26(9), pp. 2544-2554. (doi: 10.1523/JNEUROSCI.4322-05.2006) (PMID:16510732)

2004

Massey, P. V., Johnson, B. E., Moult, P. R., Auberson, Y. P., Brown, M. W., Molnar, E., Collingridge, G. L. and Bashir, Z. I. (2004) Differential roles of NR2A and NR2B-containing NMDA receptors in cortical long-term potentiation and long-term depression. Journal of Neuroscience, 24(36), pp. 7821-7828. (doi: 10.1523/JNEUROSCI.1697-04.2004) (PMID:15356193)

2002

Moult, P. R., Schnabel, R., Kilpatrick, I. C., Bashir, Z. I. and Collingridge, G. L. (2002) Tyrosine dephosphorylation underlies DHPG-induced LTD. Neuropharmacology, 43(2), pp. 175-180. (doi: 10.1016/S0028-3908(02)00110-7) (PMID:12213271)

This list was generated on Sat May 11 19:35:21 2024 BST.
Jump to: Articles
Number of items: 16.

Articles

Sidlauskaite, E., Gibson, J. W., Megson, I. L., Whitfield, P. D., Tovmasyan, A., Batinic-Haberle, I., Murphy, M. P., Moult, P. R. and Cobley, J. N. (2018) Mitochondrial ROS cause motor deficits induced by synaptic inactivity: implications for synapse pruning. Redox Biology, 16, pp. 344-351. (doi: 10.1016/j.redox.2018.03.012) (PMID:29587245) (PMCID:PMC5953219)

Kankia, I. H., Khalil, H. S., Langdon, S. P., Moult, P. R., Bown, J. L. and Deeni, Y. Y. (2017) NRF2 regulates HER1 signaling pathway to modulate the sensitivity of ovarian cancer cells to lapatinib and erlotinib. Oxidative Medicine and Cellular Longevity, 2017, 1864578. (doi: 10.1155/2017/1864578) (PMID:29410730) (PMCID:PMC5749283)

Cobley, J. N., Moult, P. R., Burniston, J. G., Morton, J. P. and Close, G. L. (2015) Exercise improves mitochondrial and redox-regulated stress responses in the elderly: better late than never! Biogerontology, 16(2), pp. 249-264. (doi: 10.1007/s10522-014-9546-8) (PMID:25537184)

Moult, P. R., Cottrell, G. A. and Li, W.-C. (2013) Fast silencing reveals a lost role for reciprocal inhibition in locomotion. Neuron, 77(1), pp. 129-140. (doi: 10.1016/j.neuron.2012.10.040) (PMID:23312521) (PMCID:PMC3542422)

Li, W.-C. and Moult, P. R. (2012) The control of locomotor frequency by excitation and inhibition. Journal of Neuroscience, 32(18), pp. 6220-6230. (doi: 10.1523/JNEUROSCI.6289-11.2012) (PMID:22553028) (PMCID:PMC3351984)

Moult, P. R. and Harvey, J. (2011) NMDA receptor subunit composition determines the polarity of leptin-induced synaptic plasticity. Neuropharmacology, 61(5-6), pp. 924-936. (doi: 10.1016/j.neuropharm.2011.06.021) (PMID:21752339) (PMCID:PMC3300059)

Moult, P. R., Cross, A., Santos, S. D., Carvalho, A.-L., Lindsay, Y., Connolly, C. N., Irving, A. J., Leslie, N. R. and Harvey, J. (2010) Leptin regulates AMPA receptor trafficking via PTEN inhibition. Journal of Neuroscience, 30(11), pp. 4088-4101. (doi: 10.1523/JNEUROSCI.3614-09.2010) (PMID:20237279) (PMCID:PMC2843829)

Moult, P. R. (2009) Neuronal glutamate and GABAA receptor function in health and disease. Biochemical Society Transactions, 37(6), pp. 1317-1322. (doi: 10.1042/BST0371317) (PMID:19909268)

Moult, P. R. and Harvey, J. (2009) Regulation of glutamate receptor trafficking by leptin. Biochemical Society Transactions, 37(6), pp. 1364-1368. (doi: 10.1042/BST0371364) (PMID:19909277) (PMCID:PMC2808539)

Moult, P. R., Milojkovic, B. and Harvey, J. (2009) Leptin reverses long-term potentiation at hippocampal CA1 synapses. Journal of Neurochemistry, 108(3), pp. 685-696. (doi: 10.1111/j.1471-4159.2008.05810.x) (PMID:19054283) (PMCID:PMC2638023)

Solovyova, N., Moult, P. R., Milojkovic, B., Lambert, J. J. and Harvey, J. (2009) Bi-directional modulation of fast inhibitory synaptic transmission by leptin. Journal of Neurochemistry, 108(1), pp. 190-201. (doi: 10.1111/j.1471-4159.2008.05751.x) (PMID:19094063) (PMCID:PMC2605943)

Moult, P. R., Corrêa, S. A.L., Collingridge, G. L., Fitzjohn, S. M. and Bashir, Z. I. (2008) Co-activation of p38 mitogen-activated protein kinase and protein tyrosine phosphatase underlies metabotropic glutamate receptor-dependent long-term depression. Journal of Physiology, 586(10), pp. 2499-2510. (doi: 10.1113/jphysiol.2008.153122) (PMID:18356198)

Moult, P. R. and Harvey, J. (2008) Hormonal regulation of hippocampal dendritic morphology and synaptic plasticity. Cell Adhesion and Migration, 2(4), pp. 269-275. (doi: 10.4161/cam.2.4.6354) (PMID:19262152) (PMCID:PMC2633690)

Moult, P. R., Gladding, C. M., Sanderson, T. M., Fitzjohn, S. M., Bashir, Z. I., Molnar, E. and Collingridge, G. L. (2006) Tyrosine phosphatases regulate AMPA receptor trafficking during metabotropic glutamate receptor-mediated long-term depression. Journal of Neuroscience, 26(9), pp. 2544-2554. (doi: 10.1523/JNEUROSCI.4322-05.2006) (PMID:16510732)

Massey, P. V., Johnson, B. E., Moult, P. R., Auberson, Y. P., Brown, M. W., Molnar, E., Collingridge, G. L. and Bashir, Z. I. (2004) Differential roles of NR2A and NR2B-containing NMDA receptors in cortical long-term potentiation and long-term depression. Journal of Neuroscience, 24(36), pp. 7821-7828. (doi: 10.1523/JNEUROSCI.1697-04.2004) (PMID:15356193)

Moult, P. R., Schnabel, R., Kilpatrick, I. C., Bashir, Z. I. and Collingridge, G. L. (2002) Tyrosine dephosphorylation underlies DHPG-induced LTD. Neuropharmacology, 43(2), pp. 175-180. (doi: 10.1016/S0028-3908(02)00110-7) (PMID:12213271)

This list was generated on Sat May 11 19:35:21 2024 BST.

Teaching

I have a passion for teaching biological sciences and in particular neuroscience. I have strong interests in research and development of online methods of teaching and assessment, specifically in the areas of experimental design and blended practical delivery. I’m a strong believer in facilitating engagement through technology enabled processes, maximizing opportunity for higher level learning. As such I seek to develop a more blended approach to science delivery within my own practice and to promote its use more widely.  

Additional information

Editorial Board

  • - present: Plos One - Reviewer
  • - present: Bioscience Horizons - Reviewer
  • - present: Nature Communications - Reviewer
  • - present: Medical Research Foundation - Reviewer of grants
  • - present: Neuropharmacology (Elsevier) - Reviewer
  • - present: Journal of Neurochemistry - Reviewer

Research Fellowship

  • - present: Higher Education Academy

Dr Peter Moult