Dr Steven Neale

Dr Steven L Neale
  • EPSRC Research Fellow (Biomedical Engineering)

telephone: 01413302411
email: Steven.Neale@glasgow.ac.uk


Biography

Dr. Neale took an M.Sci. in Physics at the University of St. Andrews.  He remained at St. Andrews to undertake a Ph.D. under the supervision of Professor Thomas F. Krauss in collaboration with Professor Kishan Dholakia.  After completing his Ph.D. he spent a further year as a post doc in Professor Krauss's group before moving to UC Berkeley where he spent two years as a post doc with Professor Ming C Wu in the department of Electrical Engineering and Computer Science.  In 2009 Dr. Neale was awarded a Royal Academy of Engineering Research Fellowship which he is currently undertaking with Professor Jon Cooper's Advanced Medical Diagnostics at The University of Glasgow.


Research Interests

Dr. Neale's research interests are in the use of electrical engineering techniques to create new tools for use in the life sciences.  More specifically research using micromanipulation techniques to place forces on biological samples in order to study their responses.  Using tools such as optical tweezers (OT), dielectrophoresis (DEP) and the recently developed Optoelectronic Tweezers (OET), which allows the DEP force to be light patterned, forces are placed on samples including blood borne parasites, red blood cells, cells from in vitro cell lines such as HeLa cells and structured inorganic micro and nanoparticles.


Expertise

Microfabrication, optics, micromanipulation, optical tweezers, dielectrophoresis and Optoelectronic Tweezers (OET).

Jump to: 2012 | 2011 | 2010 | 2009
Number of items: 27.

2012

Neale, S.L., Witte, C., Bourquin, Y., Kremer, C., Menachery, A. , Zhang, Y. , Wilson, R. , Reboud, J. , and Cooper, J.M. (2012) New optical, acoustic, and electrical diagnostics for the developing world. Proceedings of the SPIE - the International Society for Optical Engineering, 8251 . p. 825102. ISSN 0277-786X (doi:10.1117/12.924357)

2011

Zarowna-Dabrowska, A. et al. (2011) Miniaturized optoelectronic tweezers controlled by GaN micro-pixel light emitting diode arrays. Optics Express, 19 (3). pp. 2720-2728. ISSN 1094-4087 (doi:10.1364/OE.19.002720)

Reboud, J., Wilson, R. , Bourquin, Y., Zhang, Y. , Neale, S.L. , and Cooper, J.M. (2011) Phononic fluidics: acoustically activated droplet manipulations. Proceedings of the SPIE - the International Society for Optical Engineering, 7929 . 79290L. ISSN 0277-786X (doi:10.1117/12.879148)

Wilson, R., Reboud, J. , Bourquin, Y., Neale, S. , Zhang, Y. , and Cooper, J. (2011) Phononic crystal structures for acoustically driven microfluidic manipulations. Lab On a Chip, 11 (2). pp. 323-328. ISSN 1473-0197 (doi:10.1039/C0LC00234H)

2010

Clemens, K., Neale, S. , Barrett, M., and Cooper, J. (2010) Manipulating blood borne parasites with optoelectronic tweezers (OET). In: IOP Photon10, 23-26 August 2010, University of Southampton, UK.

Hsu, H., Ohta, A., Chiou, P., Jamshidi, A., Neale, S. , and Wu, M. (2010) Phototransistor-based optoelectronic tweezers for dynamic cell manipulation in cell culture media. Lab On a Chip, 10 (2). pp. 165-172. ISSN 1473-0197 (doi:10.1039/b906593h)

Jamshidi, A., Valley, J., Lam, W., Hsu, H., Dai, T., Shekarchian, S., Neale, S. , Pei, S., and Wu, M. (2010) An integrated single cell optofluidic platform based on phototransistor optoelectronic tweezers. In: Quantum Electronics and Laser Science Conference, 16-21 May 2010, San Jose, CA, USA.

Ohta, A.T., Garcia, M., Valley, J.K., Banie, L., Hsu, H., Jamshidi, A., Neale, S. , Lue, T., and Wu, M.C. (2010) Motile and non-motile sperm diagnostic manipulation using optoelectronic tweezers. Lab On a Chip, 10 (23). pp. 3213-3217. ISSN 1473-0197 (doi:10.1039/c0lc00072h)

Pei, S.N., Valley, J.K., Neale, S. , Jamshidi, A., Hsu, H.-Y., and Wu, M.C. (2010) Projector-based continuous optoelectrowetting for real-time reconfigurable digital micofluidics. In: 23rd IEEE International Conference on Micro Electro Mechanical Systems (MEMS 2010), 24-28 Jan 2010, Hong Kong.

Reboud, J., Wilson, R. , Bourquin, Y., Zhang, Yi. , Neale, S. , and Cooper, J. (2010) Phononic crystal metamaterials for frequency tuneable microfluidic functions using surface acoustic waves. In: 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS(2010)), 3-7 Oct. 2010, Groningen, Netherlands.

Valley, J.K., Garcia, M., Swinton, P., Neale, S. , Hsu, H.Y., Jamshidi, A., and Wu, M.C. (2010) Optoelectronic tweezers for quantitative assessment of embryo development stage. In: 23rd IEEE International Conference on Micro Electro Mechanical Systems (MEMS 2010), 24-28 Jan 2010, Hong Kong.

Zarowna-Dabrowska, A. et al. (2010) Micromanipulation of beads and CHO cells using micro light emitting diode arrays to control a miniaturised optoelectronic tweezers device. In: IOP Photon10, 23-26 Aug 2010, Southampton, UK.

Zarowna-Dabrowska, A. et al. (2010) Miniaturised optoelectronic tweezers controlled by GaN micro light emitting diode arrays. In: 23rd Annual Meeting of the IEEE Photonics Society, 7-11 Nov 2010, Denver, CO.

2009

Jamshidi, A., Neale, S. , Yu, K., Pauzauskie, P.J., Schuck, P.J., Valley, J.K., Hsu, H., Ohta, A.T., and Wu, M. (2009) NanoPen: dynamic, low-power, and light-actuated patterning of nanoparticles. Nano Letters, 9 (8). pp. 2921-2925. ISSN 1530-6984 (doi:10.1021/nl901239a)

Neale, S., Ohta, A., Hsu, H., Valley, J., Jamshidi, A., and Wu, M. (2009) Trap profiles of projector based optoelectronic tweezers (OET) with HeLa cells. Optics Express, 17 (7). pp. 5231-5239. ISSN 1094-4087 (doi:10.1364/OE.17.005231)

Fan, Z. et al. (2009) Three-dimensional nanopillar-array photovoltaics on low-cost and flexible substrates. Nature Materials, 8 (8). pp. 648-653. ISSN 1476-1122 (doi:10.1038/nmat2493)

Hsu, H.Y., Lee, H., Pautot, S., Yu, K., Neale, S. , Ohta, A.T., Jamshidi, A., Valley, J., Isocaff, E., and Wu, M.C. (2009) Sorting of differentiated neurons using phototransistor-based optoelectronic tweezers for cell replacement therapy of neurodegenerative diseases. In: Solid-State Sensors, Actuators and Microsystems Conference, 21-25 June 2009, Denver, Colorado, USA.

Jamshidi, A., Hsu, H.Y., Valley, J.K., Ohta, A.T., Neale, S. , and Wu, M.C. (2009) Metallic nanoparticle manipulation using optoelectronic tweezers. In: IEEE 22nd International Conference on Micro Electro Mechanical Systems MEMS, 25-29 Jan 2009, Sorrento, Italy.

Jamshidi, A., Schuck, P.J., Pauzauskie, P.J., Valley, J.K., Hsu, H.Y., Ohta, A.T., Neale, S. , and Wu, M.C. (2009) NanoPen: light-actuated patterning of nanoparticles. In: IEEE/LEOS Winter Topicals Meeting Series, 12-14 Jan 2009, Innsbruck, Austria.

Neale, S., Hsu, H.Y., Valley, J.K., Jamshidi, A., and Wu, M.C. (2009) Using MEMs mirrors to pattern electrical forces. In: SPIE Photonics West, 24-29 Jan 2009, San Jose, CA, USA.

Neale, S., Ohta, A.T., Hsu, H.Y., Valley, J.K., Jamshidi, A., and Wu, M.C. (2009) Force versus position profiles of HeLa ccells trapped in phototransistor-based optoelectronic tweezers. In: SPIE Photonics West, 24-29 Jan 2009, San Jose, CA, USA.

Neale, Steven, Fan, Z., Ohta, A.T., Jamshidi, A., Valley, J.K., Hsu, H.Y., Javey, A., and Wu, M.C. (2009) Optofluidic assembly of red/blue/green semiconductor nanowires. In: Conference on Lasers and Electro-Optics and Quantum Electronics and Laser Science Conference (CLEO/QELS 2009), 31 May - 5 June 2009, Baltimore, USA.

Tien, M., Ohta, A.T., Yu, K., Neale, S. , and Wu, M.C. (2009) Heterogeneous integration of InGaAsP microdisk laser on a silicon platform using optofluidic assembly. Applied Physics A, 95 (4). pp. 967-972. ISSN 0947-8396 (doi:10.1007/s00339-009-5125-2)

Tien, M.C., Yu, K., Ohta, A.T., Neale, S. , and Wu, M.C. (2009) Optofluidic assembly of InGaAsP microdisk lasers on Si photonic circuits with submicron alignment accuracy. In: Optical Fiber Communication (OFC) and the National Fiber Optic Engineers Conference (NFOEC), 22-26 March 2009, San Diego, CA, USA.

Valley, J.K., Hsu, H.Y., Neale, S. , Ohta, A.T., Jamshidi, A., and Wu, M.C. (2009) Assessment of single cell viability following light-induced electroporation through use of on-chip microfluidics. In: IEEE 22nd International Conference on Micro Electro Mechanical Systems MEMS, 25-29 Jan 2009, Sorrento, Italy.

Valley, J.K., Neale, S. , Hsu, H.-Y., Ohta, A.T., Jamshidi, A., and Wu, M.C. (2009) Parallel single-cell light-induced electroporation and dielectrophoretic manipulation. Lab On a Chip, 9 (12). pp. 1714-1720. ISSN 1473-0197 (doi:10.1039/b821678a)

Wu, M.C., Jamshidi, A., Neale, S. , Tien, M.C., Ohta, A.T., and Yu, K. (2009) Optoelectronic Tweezers - a New Parallel Optical Manipulation Tool. In: Solid-State Sensors, Actuators and Microsystems Conference, 21-25 June 2009, Denver, Colorado, USA.

This list was generated on Thu May 24 16:51:26 2012 BST.

1.  £645,000 “Micro Actuators Controlled by Optoelectronic Tweezers (MacOET)” RAEng Research Fellowship, awarded April 2009, started 1st August 2009.

2.  £14996.53 “Hybrid Acoustic and Electric Tweezers for the Life Sciences” Royal Society Research Grants scheme, 1st Jan 2011 to 31st Dec 2012.

3.  £8084.42 “Combining Surface Acoustic Waves (SAW) with Optoelectronic Tweezers (OET)” – Awarded by the EEE department’s PI fund. Awarded 9th March 2010.

4.  £2382, “Using optoelectronic tweezers to measure the Young’s modulus of red blood cells as a biomarker of ageing and obesity” – Awarded by the Scottish Crucible with collaborators Nimesh Mody and Colin Selman from Aberdeen University. Awarded 6th September 2010.

I supervise Christian Witte and I am the second supervisor of Ngoc Duy Dinh.

Electronic Devices II, Microwave Electronic and Optoelectronic Devices IV.