Dr Andrew Glidle
- Research Technologist (Biomedical Engineering)
telephone: 01413302000ext0928
email: Andrew.Glidle@glasgow.ac.uk
Biography
Andrew Glidle studied Maths and Chemistry at Exeter University and graduated in 1988 with a PhD in Electrochemistry from Dr David Rosseinsky’s group. He then moved to Bristol University to work with Prof. Rob Hillman (currently at Leicester University) on developing the Electrochemical Quartz Crystal Microbalance technique for the study of transport and viscoelastic processes in polymer films as they undergo redox transformations.
After a few years in Bristol he moved to Glasgow to work with Dr Bob Peacock in the Inorganic Chemistry department investigating electrochemical sensors for chiral molecule detection. During this time he began working with Jon Cooper of the Bioelectronics group in EEE and later took up an opportunity to work in the then emerging field of Molecular Electronics.
Throughout his career, alongside interests in spectroscopy and the use of electron transfer to change the properties of materials such as their colour, conductivity or catalytic behaviour, he has always been interested developing new methods of measuring things. These have included both devising new, often hybrid, instrumental techniques, and using the functional building blocks found in synthetic and biological chemistry.
These interests have lead to him developing innovations and expertise in many methods of surface analysis, ranging from x-ray photoelectron spectroscopy to optical and infra-red techniques to neutron scattering methods. With the advent of Lab-on-a-chip devices he has also been keen to develop ways in which macroscopic characterisation and assaying techniques can be adapted and robustly implemented within these small devices, using his background in synthetic and physical chemistry to incorporate novel functionalities or solve technological problems. His current research activities include new methods for characterising sensor materials and LOAC structures using Neutron Scattering (with Prof Rob Hillman and Dr Karl Ryder at Leicester) at the Institut Laue Langevin (Grenoble), ISIS (Rutherford Lab) and SINQ (PSI, Switzerland) and XPS (Daresbury); new methods of fabrication and control of integrated microfluidic devices; developing functional surface architectures for the incorporation of (bio)chemical sensors and separation systems into LOAC devices; QCM and SAW sensors; new methods in SPR and SERS assaying. He is on the Scientific Panel of STFC’s National Centre for Electron Spectroscopy and is regularly invited to present his work at international Electrochemistry and Neutron Scattering conferences.
Article
Zarowna-Dabrowska, A. et al. (2012) Generation of primary hepatocyte microarrays by piezoelectric printing. Colloids and Surfaces B: Biointerfaces, 89 . pp. 126-132. ISSN 0927-7765 (doi:10.1016/j.colsurfb.2011.09.016)
Hu, Z., Glidle, A., Ironside, C.N., Sorel, M., Strain, M.J., Cooper, J., and Yin, H. (2012) Integrated microspectrometer for fluorescence based analysis in a microfluidic format. Lab On a Chip, 12 (16). pp. 2850-2857. ISSN 1473-0197 (doi:10.1039/C2LC40169J)
Cooper, J., Glidle, A., and De La Rue, R. (2010) Photonic crystal structures in molecular biosensing. Optics and Photonics News, 21 (9). pp. 26-31. ISSN 1047-6938 (doi:10.1364/OPN.21.9.000026)
Hillman, A.R. et al. (2010) Structure and dynamics of phospholipid bilayer films under electrochemical control. Faraday Discussions, 145 . pp. 357-379. ISSN 1359-6640 (doi:10.1039/b911246b)
Rauf, S., Glidle, A., and Cooper, J.M. (2010) Application of quantum dot barcodes prepared using biological self-assembly to multiplexed immunoassays. Chemical Communications, 46 (16). pp. 2814-2816. ISSN 1359-7345 (doi:10.1039/B927149J )
Rauf, S., Glidle, A., and Cooper, J.M. (2010) Layer-by-layer quantum dot constructs using self-assembly methods. Langmuir, 26 (22). p. 16934. ISSN 0743-7463 (doi:10.1021/la103385s)
Glidle, A., Hillman, A.R., Ryder, K.S., Smith, E.L., Cooper, J.M., Dalgliesh, R., Cubitt, R., and Geue, T. (2009) Metal chelation and spatial profiling of components in crown ether functionalised conducting copolymer films. Electrochimica Acta, 55 (2). pp. 439-450. ISSN 0013-4686 (doi:10.1016/j.electacta.2009.04.027)
Clark, A.W., Glidle, A., Cumming, D.R.S., and Cooper, J.M. (2009) Plasmonic split-ring resonators as dichroic nanophotonic DNA biosensors. Journal of the American Chemical Society, 131 (48). pp. 17615-17619. ISSN 0002-7863 (doi:10.1021/ja905910q)
Glidle, A., Hillman, A.R., Rydeo, K.S., Smith, E.L., Cooper, J.M., Gadegaard, N., Webster, J.R.P., Dalgliesh, R., and Cubitt, R. (2009) Use of neutron reflectivity to measure the dynamics of solvation and structural changes in polyvinylferrocene films during electrochemically controlled redox cycling. Langmuir, 25 (7). pp. 4093-4103. ISSN 0743-7463 (doi:10.1021/la803234e)
Blanco-Gomez, G., Glidle, A., Flendrig, L.M., and Cooper, J.M. (2009) Creation of super-hydrophobic siloxane-modified SU-8 microstuctures. Microelectronic Engineering, 86 (4-6). pp. 1325-1328. ISSN 0167-9317 (doi:10.1016/j.mee.2008.11.069)
Blanco-Gomez, G., Glidle, A., Flendrig, L.M., and Cooper, J.M. (2009) Integration of low-power microfluidic pumps with biosensors within a Laboratory-on-a-Chip device. Analytical Chemistry, 81 (4). pp. 1365-1370. ISSN 0003-2700 (doi:10.1021/ac802006d)
Burt, D.P., Whyte, W.M., Weaver, J.M.R., Glidle, A., Edgeworth, J.P., Macpherson, J.V., and Dobson, P.S. (2009) Effects of metal underlayer grain size on carbon nanotube growth. Journal of Physical Chemistry C, 113 (34). pp. 15133-15139. ISSN 1932-7447 (doi:10.1021/jp902117g)
Cleary, A., Clark, A., Glidle, A., Cooper, J.M., and Cumming, D.R.S. (2009) Fabrication of double split metallic nanorings for Raman sensing. Microelectronic Engineering, 86 (4-6). pp. 1146-1149. ISSN 0167-9317 (doi:10.1016/j.mee.2009.02.008 )
Rauf, S., Glidle, A., and Cooper, J.M. (2009) Production of quantum dot barcodes using biological self-assembly. Advanced Materials, 21 (40). pp. 4020-4024. ISSN 0935-9648 (doi:10.1002/adma.200900223)
Yin, H., Bozhi, J., Dobson, P.S., Mosbahi, K., Glidle, A., Gadegaard, N., Freer, A., Cooper, J.M., and Cusack, M. (2009) Screening of biomineralization using microfluidics. Analytical Chemistry, 81 (1). pp. 473-478. ISSN 0003-2700 (doi:10.1021/ac801980b)
Clark, A.W., Glidle, A., Cumming, D.R.S., and Cooper, J.M. (2008) Nanophotonic split-ring resonators as dichroics for molecular spectroscopy. Applied Physics Letters, 93 (2). 023121. ISSN 0003-6951 (doi:10.1063/1.2956389)
Bandeira, M.C.E., Crayston, J.A., Concalves, N.S., Noda, L.K., Glidle, A., and Franco, C.V. (2007) Electropolymerization of trans-[RuCl2(vpy)(4)] complex-EQCM and Raman studies. Journal of Solid State Electrochemistry, 11 (2). pp. 231-239. ISSN 1432-8488 (doi:10.1007/s10008-005-0093-8)
Bandeira, M.C.E., Crayston, J.A., Franco, C.V., and Glidle, A. (2007) Electrochemical deposition of poly(trans-[RuCl2(4-vinylpyridine)(4)]) and its reductive desorption: cyclic voltammetry and electrochemical quartz crystal microbalance studies. Physical Chemistry Chemical Physics, 9 (8). pp. 1003-1012. ISSN 1463-9076 (doi:10.1039/b613242a)
Clark, A.W., Sheridan, A.K., Glidle, A., Cumming, D.R.S., and Cooper, J.M. (2007) Tuneable visible resonances in crescent shaped nano-split-ring resonators. Applied Physics Letters, 91 . ISSN 0003-6951 (doi:10.1063/1.2772180)
Cleary, A., Glidle, A., Laybourn, P.J.R., Garcia-Blanco, S., Pellegrini, S., Helfter, C., Buller, G.S., Aitchison, J.S., and Cooper, J.M. (2007) Integrating optics and microfluidics for time-correlated single-photon counting in lab-on-a-chip devices. Applied Physics Letters, 91 (7). 071123. (doi:10.1063/1.2772175)
Etorki, A.M., Hillman, A.R., Ryder, K.S., and Glidle, A. (2007) Quartz crystal microbalance determination of trace metal ions in solution. Journal of Electroanalytical Chemistry, 599 (2). pp. 275-287. ISSN 1572-6657 (doi:10.1016/j.jelechem.2006.03.020)
Glidle, A., Pearson, P.E., Smith, E.L., Cooper, J.M., Cubitt, R., Dalgliesh, R.M., Hillman, A.R., and Ryder, K.S. (2007) Determining compositional profiles within conducting polymer films following reaction with vapor phase reagents. Journal of Physical Chemistry B, 111 (16). pp. 4043-4053. ISSN 1520-6106 (doi:10.1021/jp0635720)
Kennedy, B., Glidle, A., and Cunnane, V.J. (2007) A study of the oxidation and polymerisation of meta substituted phenol and aniline derivatives. Journal of Electroanalytical Chemistry, 608 (1). pp. 22-30. ISSN 1572-6657 (doi:10.1016/j.jelechem.2007.05.006)
Mills, C.A., Beeley, J., Wyse, C,, Cumming, D.R.S., Glidle, A., and Cooper, J.M. (2007) Polymer-based micro-sensor paired arrays for the determination of primary alcohol vapors. Sensors and Actuators B: Chemical, 125 (1). pp. 85-91. ISSN 0925-4005 (doi:10.1016/j.snb.2007.01.039)
Sheridan, A.K., Clark, A.W., Glidle, A., Cooper, J.M., and Cumming, D.R.S. (2007) Fabrication and tuning of nanoscale metallic ring and split-ring arrays. Journal of Vacuum Science and Technology Part B: Microelectronics and Nanometer Structures, 25 (6). p. 2628. ISSN 1071-1023 (doi:10.1116/1.2794328)
Sheridan, A.K., Clark, A.W., Glidle, A., Cooper, J.M., and Cumming, D.R.S. (2007) Multiple plasmon resonances from gold nanostructures. Applied Physics Letters, 90 (14). p. 143105. ISSN 0003-6951 (doi:10.1063/1.2719161)
Mills, C.A., Chai, K.T.C., Milgrew, M.J., Glidle, A., Cooper, J.M., and Cumming, D.R.S. (2006) A multiplexed impedance analyzer for characterizing polymer-coated QCM sensor arrays. IEEE Sensors Journal, 6 (4). pp. 996-1002. ISSN 1530-437X (doi:10.1109/JSEN.2006.877936)
Abbott, A.P., Capper, G., McKenzie, K.J., Glidle, A., and Ryder, K.S. (2006) Electropolishing of stainless steels in a choline chloride based ionic liquid: an electrochemical study with surface characterisation using SEM and atomic force microscopy. Physical Chemistry Chemical Physics, 8 . pp. 4214-4221. ISSN 1463-9076 (doi:10.1039/b607763n)
Bates, A.D. et al. (2006) Construction and characterization of a gold nanoparticle wire assembled using Mg2+-dependent RNA-RNA interactions. Nano Letters, 6 (3). pp. 445-448. ISSN 1530-6984 (doi:10.1021/nl052316g)
Cumming, D.R.S. et al. (2006) Gold nanoparticle wires made using RNA-based self-assembly. Journal of Vacuum Science and Technology Part B: Microelectronics and Nanometer Structures, 24 (6). pp. 3196-3199. ISSN 1071-1023 (doi:10.1116/1.2363404)
Macintyre, D.S., Young, I., Glidle, A., Cao, X., Weaver, J.M.R., and Thoms, S. (2006) High resolution e-beam lithography using a thin titanium layer to promote resist adhesion. Microelectronic Engineering, 83 (4-9). pp. 1128-1131. ISSN 0167-9317 (doi:10.1016/j.mee.2006.01.103)
Xu, C. et al. (2006) A combined top-down bottom-up approach for introducing nanoparticle networks into nanoelectrode gaps. Nanotechnology, 17 (14). pp. 3333-3339. ISSN 0957-4484 (doi:10.1088/0957-4484/17/14/001)
Cleary, A., Garcia-Blanco, S., Glidle, A., Aitchison, J.S., Laybourn, P., and Cooper, J.M. (2005) An integrated fluorescence array as a platform for lab-on-a-chip technology using multimode interference splitters. IEEE Sensors Journal, 5 (6). pp. 1315-1320. ISSN 1530-437X (doi:10.1109/JSEN.2005.857880)
Glidle, A., Hadyoon, C.S., Gadegaard, N., Cooper, J.M., Hillman, A.R., Wilson, A.R., Ryder, K.S., Webster, J.R.P., and Cubitt, R. (2005) Evaluating the influence of deposition conditions on solvation of reactive conducting polymers with neutron reflectivity. Journal of Physical Chemistry B, 109 (30). pp. 14335-14343. ISSN 1520-6106 (doi:10.1021/jp0515030)
Yasukawa, T., Glidle, A., Nomura, M., and Cooper, J.M. (2005) Fabrication of robust 2-D and 3-D microfluidic networks for lab-on-a-chip bioassays. Journal of Microelectromechanical Systems, 14 (4). pp. 839-846. ISSN 1057-7157 (doi:10.1109/JMEMS.2005.846358)
Wyse, C.A. et al. (2004) Current and future uses of breath analysis as a diagnostic tool. Veterinary Record, 154 (12). pp. 353-360. ISSN 0042-4900 (doi:10.1136/vr.154.12.353)
Beeley, J.M., Mills, C., Hammond, P.A., Glidle, A., Cooper, J.M., Wang, L., and Cumming, D.R.S. (2004) All-digital interface ASIC for a QCM-based electronic nose. Sensors and Actuators B: Chemical, 103 (1-2). pp. 31-36. ISSN 0925-4005 (doi:10.1016/j.snb.2004.02.059)
Cooper, J.M., Cubitt, R., Dalgliesh, R.M., Gadegaard, N., Glidle, A., Hillman, A.R., Mortimer, R.J., Ryder, K.S., and Smith, E.L. (2004) Dynamic in situ electrochemical neutron reflectivity measurements. Journal of the American Chemical Society, 126 (47). pp. 15362-15363. ISSN 0002-7863 (doi:10.1021/ja044682s)
Cooper, J.M., Glidle, A., Hillman, A.R., Ingram, M.D., Ryder, C., and Ryder, K.S. (2004) The solid-state reaction of a functionalised polypyrrole; analysis using high resolution X-ray photoelectron spectroscopy. Physical Chemistry Chemical Physics, 6 . pp. 2403-2408. ISSN 1463-9076 (doi:10.1039/b401320d)
Garcia-Blanco, S., Glidle, A., Cooper, J.M., De La Rue, R.M., and Aitchison, J.S. (2004) Characterization of germanium-doped silica layers deposited by flame-hydrolysis. Optical Materials, 27 (3). pp. 365-371. ISSN 0925-3467 (doi:10.1016/j.optmat.2004.03.018)
Garcia-Blanco, S., Kellock, A.J., Baglin, J.E.E., Glidle, A., Cooper, J.M., Aitchison, J.S., and De La Rue, R.M. (2003) Fabrication of optical waveguides by 2 MeV Ar+ irradiation of germanium-doped flame-hydrolysis deposited silica. Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, 206 . pp. 440-443. (doi:10.1016/S0168-583X(03)00789-4)
Glidle, A., Cooper, J.M., Hillman, A.R., Bailey, L., Jackson, A., and Webster, J.R.P. (2003) Redox controlled partition and spatial distribution of solvent and salt in electroactive polyvinylferrocene films. Langmuir, 19 (19). pp. 7746-7753. ISSN 0743-7463 (doi:10.1021/la027053+)
Glidle, A., Yasukawa, T., Hadyoon, C.S., Anicet, N., Matsue, T., Nomura, M., and Cooper, J.M. (2003) Analysis of protein adsorption and binding at biosensor polymer interfaces using X-ray photon spectroscopy and scanning electrochemical microscopy. Analytical Chemistry, 75 (11). pp. 2559-2570. ISSN 0003-2700 (doi:10.1021/ac0261653)
Ruano, J.M., Glidle, A., Cleary, A., Walmsley, A., Aitchison, J.S., and Cooper, J.M. (2003) Design and fabrication of a silica on silicon integrated optical biochip as a fluorescence microarray platform. Biosensors and Bioelectronics, 18 . pp. 175-184. ISSN 0956-5663
Cai, X., Cooper, J.M., Klauke, N., Glidle, A., Cui, L., and Cui, D.F. (2002) Bio-electrochemical characterization of micromachined two-electrode cell sensors. International Journal of Nonlinear Sciences and Numerical Simulation, 3 . pp. 173-176. ISSN 1565-1339
Cai, X., Klauke, N., Glidle, A., Cobbold, P., Smith, G.L., and Cooper, J.M. (2002) Ultra-low-volume, real-time measurements of lactate from the single heart cell using microsystems technology. Analytical Chemistry, 74 (4). pp. 908-914. ISSN 0003-2700 (doi:10.1021/ac010941+)
Hillman, A.R., Bailey, L., Glidle, A., Cooper, J.M., Gadegaard, N., and Webster, J.R.P. (2002) Spatial distributions of polymer and mobile species in poly(o-toluidine) films. Journal of Electroanalytical Chemistry, 532 . pp. 269-276. ISSN 1572-6657
Sandison, M.E., Anicet, N., Glidle, A., and Cooper, J.M. (2002) Optimization of the geometry and porosity of microelectrode arrays for sensor design. Analytical Chemistry, 74 (22). pp. 5717-5725. ISSN 0003-2700 (doi:10.1021/ac025649w)
Yasukawa, T., Glidle, A., Cooper, J.M., and Matsue, T. (2002) Electroanalysis of metabolic flux from single cells in simple picoliter-volume microsystems. Analytical Chemistry, 74 (19). pp. 5001-5008. ISSN 0003-2700 (doi:10.1021/ac025836u)
Blanco, S.G., Glidle, A., Davies, J.H., Aitchison, J.S., and Cooper, J.M. (2001) Electron-beam-induced densification of Ge-doped flame hydrolysis silica for waveguide fabrication. Applied Physics Letters, 79 . pp. 2889-2891. ISSN 0003-6951
Glidle, A. (2001) Temporal and spatial profiling of an immobilisation reaction at a polymer modified electrode interface using neutron reflectivity. Analytical Chemistry, 73 (22). pp. 5596-5606. ISSN 0003-2700
Glidle, A. et al. (2001) Temporal and spatial profiling of the modification of an electroactive polymeric interface using neutron reflectivity. Analytical Chemistry, 73 (22). pp. 5596-5606. (doi:10.1021/ac0104882)
Glidle, A., Swann, M.J., Hadyoon, C.S., Cui, L., Davis, J., Ryder, K.S., and Cooper, J.M. (2001) XPS assaying of electrodeposited copolymer composition to optimise sensor materials. Journal of Electron Spectroscopy and Related Phenomena, 121 . pp. 131-148.
Hillman, A.R., and Glidle, A. (2001) Electroactive bilayers employing conducting polymers. Part 6. Kinetic electrochemical quartz crystal microbalance measurements. Physical Chemistry Chemical Physics, 3 . pp. 3447-3458. ISSN 1463-9076 (doi:10.1039/B103666C)
Conference Proceedings
Hu, Z., Glidle, A., Ironside, C.N., Sorel, M., Strain, M.J., and Yin, H. (2011) On-chip micro-spectrometer for fluorescence bio-sensing. In: CLEO Europe 2011, 22-26 May 2011, Munich, Germany.
Beeley, J., Mills, C.A., Glidle, A., Cooper, J.M., and Cumming, D.R.S. (2003) All-digital interface for a QCM-based electronic nose. In: Eurosensors XVII- 17th European Conference on Transducers, Portugal.
Garcia-Blanco, S., Glidle, A., Cooper, J.M., De La Rue, R.M., Jacqueline, A.S., Poumellec, B., and Aitchison, J.S. (2002) Characterization of the densification induced by electron-beam irradiation of ge-doped silica for the fabrication of integrated optical circuits. In: Proceedings of 2002.IEEE/LEOS.Workshop on Fibre.and Optical.Passive.Components.Cat, USA.