Professor Willie Weir

Professor of Veterinary Infectious Disease (Veterinary Pathology, Public Health & Disease Investigation)

telephone: 01413308654
email: Willie.Weir@glasgow.ac.uk

Room 313, Jarrett Building, University of Glasgow Veterinary School, Garscube Estate, Bearsden Road, G61 1QH

Research interests

My research is mainly in the field of veterinary infectious disease, principally tick-borne pathogens (Babesia, Theileria and Anaplasma), Giardia and Trypanosomes. I apply population genetic and genomic approaches to investigate diversity in pathogen populations together with transcriptomics, which allows the characterisation of cellular interactions at the host/parasite interface. I am particularly interested in emerging tick-borne veterinary pathogens in the UK, such as equine piroplasmosis, and the development of novel diagnostic assays for their detection.

I am also interested in the identification and validation of novel biomarkers for both infectious and non-infectious disease. This entails the bioinformatic mining of high-throughput sequencing datasets for diagnostic and prognostic applications. The ultimate goal of this research is the development of novel diagnostic approaches which will assist veterinary surgeons in their clinical decision making.

Research groups

Publications

List by: Type | Date

Jump to: 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2007 | 2006 | 2005 | 2003

Number of items: 102.

2024

Dunbar, D., Babayan, S. A. , Krumrie, S. , Haining, H., Hosie, M. J. and Weir, W. (2024) Assessing the feasibility of applying machine learning to diagnosing non-effusive feline infectious peritonitis. Scientific Reports, 14, 2517. (doi: 10.1038/s41598-024-52577-4) (PMID:38291072)

2023

Fulton, E. A., Weir, W. , Czopowicz, M. and McBrearty, A. R. (2023) The relationships between sediment findings and culture results and the presence of proteinuria in canine urine samples. Journal of Small Animal Practice, 64(12), pp. 749-758. (doi: 10.1111/jsap.13669) (PMID:37632274)

Jones, S. et al. (2023) SARS-CoV-2 in domestic UK cats from Alpha to Omicron: Swab surveillance and case reports. Viruses, 15(8), 1769. (doi: 10.3390/v15081769) (PMID:37632111) (PMCID:PMC10459977)

Tyson, G. B. et al. (2023) Increase in SARS-CoV-2 seroprevalence in UK domestic felids despite weak immunogenicity of post-Omicron variants. Viruses, 15(8), 1661. (doi: 10.3390/v15081661) (PMID:37632004) (PMCID:PMC10458763)

Durrani, Z., Kinnaird, J., Cheng, C. W., Brühlmann, F., Capewell, P. , Jackson, A., Larcombe, S., Olias, P., Weir, W. and Shiels, B. (2023) A parasite DNA binding protein with potential to influence disease susceptibility acts as an analogue of mammalian HMGA transcription factors. PLoS ONE, 18(6), e0286526. (doi: 10.1371/journal.pone.0286526) (PMID:37276213) (PMCID:PMC10241358)

Tyson, G. B., Jones, S., Logan, N., McDonald, M., Marshall, L., Murcia, P. R. , Willett, B. J. , Weir, W. and Hosie, M. J. (2023) SARS-CoV-2 seroprevalence and cross-variant antibody neutralization in cats, United Kingdom. Emerging Infectious Diseases, 29(6), pp. 1223-1227. (doi: 10.3201/eid2906.221755) (PMID:37141617) (PMCID:PMC10202862)

Joyce, H., Oliver, J. A. C., Fricker, G., Weir, W. and Fleming, L. (2023) Keratouveitis in juvenile dogs and its presumed association with canine adenovirus infection. Veterinary Ophthalmology, 26(3), pp. 262-267. (doi: 10.1111/vop.13085) (PMID:36999558)

Panarese, R., Moore, R., Page, A. P. , McDonald, M. , MacDonald, E. and Weir, W. (2023) The long-distance relationship between Dirofilaria and the UK: case report and literature review. Frontiers in Veterinary Science, 10, 1128188. (doi: 10.3389/fvets.2023.1128188) (PMID:37180057) (PMCID:PMC10172649)

Pagnossin, D., Weir, W. , Smith, A., Fuentes, M. , Coelho, J. and Oravcova, K. (2023) Streptococcus canis genomic epidemiology reveals the potential for zoonotic transfer. Microbial Genomics, 9(3), 000974. (doi: 10.1099/mgen.0.000974) (PMID:37000493) (PMCID:PMC10132062)

Hacılarlıoglu, S., Bilgic, H. B., Bakırcı, S., Tait, A., Weir, W. , Shiels, B. and Karagenc, T. (2023) Selection of genotypes harbouring mutations in the cytochrome b gene of Theileria annulata is associated with resistance to buparvaquone. PLoS ONE, 18(1), e0279925. (doi: 10.1371/journal.pone.0279925) (PMID:36598898) (PMCID:PMC9812330)

2022

Krumrie, S. , Capewell, P. , McDonald, M. , Dunbar, D., Panarese, R., Katzer, F., El Sakka, N., Mellor, D. , Alexander, C. L. and Weir, W. (2022) Molecular characterisation of Giardia duodenalis from human and companion animal sources in the United Kingdom using an improved triosephosphate isomerase molecular marker. Current Research in Parasitology and Vector-Borne Diseases, 2(2022), 100105. (doi: 10.1016/j.crpvbd.2022.100105) (PMID:36504596) (PMCID:PMC9731890)

Johnston, P. E.J. , Gray, A., Weir, W. , Wigham, E., Mercer, A., McGuigan, M. and Anderson, J. (2022) Livestreaming can augment the observation of veterinary post-mortem examinations. In: Varsou, O., Rea, P. M. and Welsh, M. (eds.) Biomedical Visualisation: Volume 14 ‒ COVID-19 Technology and Visualisation Adaptations for Biomedical Teaching. Series: Advances in experimental medicine and biology (1397). Springer: Cham, pp. 113-134. ISBN 9783031171345 (doi: 10.1007/978-3-031-17135-2_7)

Pagnossin, D., Smith, A. , Oravcova, K. and Weir, W. (2022) Streptococcus canis, the underdog of the genus. Veterinary Microbiology, 273, 109524. (doi: 10.1016/j.vetmic.2022.109524) (PMID:35933975)

McManus, R., Boden, L., Weir, W. , Viora, L. , Barker, R., Kim, Y. , McBride, P. and Yang, S. (2022) Thermography for Disease Detection in Livestock. In: European College of Veterinary Public Health Annual Scientific Conference 2022, Athens, Greece, 28-30 September 2022,

McManus, R., Boden, L., Weir, W. , Viora, L. , Barker, R., Kim, Y. , McBride, P. and Yang, S. (2022) Thermography for disease detection in livestock: a scoping review. Frontiers in Veterinary Science, 9, 965622. (doi: 10.3389/fvets.2022.965622) (PMID:36016809) (PMCID:PMC9395652)

Voss, S. J., McGuinness, D. H. , Weir, W. and Sutton, D. G.M. (2022) A study comparing the healthy and diseased equine glandular gastric microbiota sampled with sheathed transendoscopic cytology brushes. Journal of Equine Veterinary Science, (doi: 10.1016/j.jevs.2022.104002) (PMID:35490972)

Selim, A., Weir, W. and Khater, H. (2022) Prevalence and risk factors associated with tropical theileriosis in Egyptian dairy cattle. Veterinary World, 15(4), pp. 919-924. (doi: 10.14202/vetworld.2022.919-924) (PMID:35698515) (PMCID:PMC9178591)

Krumrie, S. , Capewell, P. , Smith-Palmer, A., Mellor, D. , Weir, W. and Alexander, C. L. (2022) A scoping review of risk factors and transmission routes associated with human giardiasis outbreaks in high-income settings. Current Research in Parasitology and Vector-Borne Diseases, 2, 100084. (doi: 10.1016/j.crpvbd.2022.100084)

Larcombe, S. D., Capewell, P. , Jensen, K., Weir, W. , Kinnaird, J., Glass, E. J. and Shiels, B. R. (2022) Susceptibility to disease (tropical theileriosis) is associated with differential expression of host genes that possess motifs recognised by a pathogen DNA binding protein. PLoS ONE, 17(1), e0262051. (doi: 10.1371/journal.pone.0262051) (PMID:35061738) (PMCID:PMC8782480)

McManus, R., Weir, W. , Viora, L. , Barker, R., Kim, Y. , McBride, P. , Yang, S. and Boden, L. (2022) Investigating Gaps For Novel Animal Health Surveillance Data Within Scotland. In: European Commission for control of foot-and-mouth disease (EUFMD) Open Session (OS22), Marseille, France, 26-28 October 2022, (Accepted for Publication)

2021

Rowland, H., Holding, E., Falces, P. M., Wissink-Argilaga, N., Stidworthy, M. F., Denk, D., Weir, W. , Krumrie, S. , Dunbar, D. and Hopper, J. S. (2021) Canine coronavirus subtype 2a associated with outbreaks of fatal diarrhoea in bush dog (Speothos venaticus) groups. Schweizer Archiv fur Tierheilkunde, 164(10), pp. 661-671. (doi: 10.17236/sat00320) (PMID:34758958)

Hosie, M. J. et al. (2021) Detection of SARS-CoV-2 in respiratory samples from cats in the UK associated with human-to-cat transmission. Veterinary Record, 188(8), e247. (doi: 10.1002/vetr.247) (PMID:33890314) (PMCID:PMC8251078)

Pagnossin, D., Smith, A. , Weir, W. , Crestani, C., Lindsay, D., Ure, R. and Oravcova, K. (2021) Complete genome sequences of three invasive strains of Streptococcus pyogenes subtype emm5.23 isolated in Scotland. Microbiology Resource Announcements, 10(15), e00101-21. (doi: 10.1128/MRA.00101-21) (PMID:33858921) (PMCID:PMC8050963)

Gray, A., Capewell, P. , Zadoks, R. , Taggart, M. A., French, A. S., Katzer, F., Shiels, B. R. and Weir, W. (2021) Wild deer in the United Kingdom are a potential reservoir for the livestock parasite. Current Research in Parasitology and Vector-Borne Diseases, 1, 100019. (doi: 10.1016/j.crpvbd.2021.100019) (PMID:35284871) (PMCID:PMC8906096)

Capewell, P. , Krumrie, S. , Katzer, F., Alexander, C. L. and Weir, W. (2021) Molecular epidemiology of Giardia infections in the genomic era. Trends in Parasitology, 37(2), pp. 142-153. (doi: 10.1016/j.pt.2020.09.013) (PMID:33067130)

2020

Coultous, R. , Leadon, D. P., Shiels, B. , Sutton, D. and Weir, W. (2020) Investigating the presence of equine piroplasmosis in Ireland. Veterinary Record, 187(11), e97. (doi: 10.1136/vr.105937) (PMID:32887846)

Mira, A. et al. (2020) High genetic diversity and differentiation of the Babesia ovis population in Turkey. Transboundary and Emerging Diseases, 67(S2), pp. 26-35. (doi: 10.1111/tbed.13174) (PMID:31231917)

Murcia, P. , Streiker, D. , Da Silva Filipe, A. , Robertson, D. , Jarrett, R. , Willett, B. , Hosie, M. , Biek, R. , Allan, K. and Weir, W. (2020) Send cat and dog samples to test for SARS-CoV-2. Veterinary Record, 186(17), p. 571. (doi: 10.1136/vr.m2019) (PMID:32451348)

Capewell, P. , Rupp, A., Fuentes, M. , McDonald, M. and Weir, W. (2020) Fatal Clostridium sordellii-mediated hemorrhagic and necrotizing gastroenteropathy in a dog: case report. BMC Veterinary Research, 16(1), 152. (doi: 10.1186/s12917-020-02362-y) (PMID:32448314) (PMCID:PMC7245850)

Coultous, R. , McDonald, M. , Raftery, A. G. , Shiels, B. , Sutton, D. G.M. and Weir, W. (2020) Analysis of Theileria equi diversity in The Gambia using a novel genotyping method. Transboundary and Emerging Diseases, 67(3), pp. 1213-1221. (doi: 10.1111/tbed.13454) (PMID:31845493)

Weir, W. , Gray, A., Shiels, B. and Katzer, F. (2020) Babesia venatorum has not ‘just arrived’ in the UK. Veterinary Record, 186(3), pp. 96-97. (doi: 10.1136/vr.m219) (PMID:31974184)

2019

Gray, A., Capewell, P. , Loney, C. , Katzer, F., Shiels, B. R. and Weir, W. (2019) Sheep as host species for zoonotic Babesia venatorum, United Kingdom. Emerging Infectious Diseases, 25(12), pp. 2257-2260. (doi: 10.3201/eid2512.190459) (PMID:31742518) (PMCID:PMC6874260)

Larcombe, S.D. et al. (2019) The impact of tick-borne pathogen infection in Indian bovines is determined by host type but not the genotype of Theileria annulata. Infection, Genetics and Evolution, 75, 103972. (doi: 10.1016/j.meegid.2019.103972) (PMID:31344487) (PMCID:PMC6853275)

Page, A. P. , Roberts, M., Felix, M.-A., Pickard, D., Page, A. and Weir, W. (2019) The golden death bacillus Chryseobacterium nematophagum is a novel matrix digesting pathogen of nematodes. BMC Biology, 17, 10. (doi: 10.1186/s12915-019-0632-x) (PMID:30813925) (PMCID:PMC6394051)

Capewell, P. et al. (2019) Resolving the apparent transmission paradox of African sleeping sickness. PLoS Biology, 17(1), e3000105. (doi: 10.1371/journal.pbio.3000105) (PMID:30633739) (PMCID:PMC6345479)

Bilgic, H. B., Aksulu, A., Bakırcı, S., Unlu, A. H., Kose, O., Hacılarlıoglu, S., Weir, W. and Karagenc, T. (2019) Infection dynamics of Theileria annulata over a disease season following cell line vaccination. Veterinary Parasitology, 265, pp. 63-73. (doi: 10.1016/j.vetpar.2018.11.012) (PMID:30638522)

Coultous, R. M., Phipps, P., Dalley, C., Lewis, J., Hammond, T.-A., Shiels, B. R. , Weir, W. and Sutton, D. G.M. (2019) Equine piroplasmosis status in the UK: an assessment of laboratory diagnostic submissions and techniques. Veterinary Record, 184(3), 95. (doi: 10.1136/vr.104855) (PMID:30413675)

2018

Dunbar, D. et al. (2018) Diagnosis of non-effusive feline infectious peritonitis by reverse transcriptase quantitative PCR from mesenteric lymph node fine-needle aspirates. Journal of Feline Medicine and Surgery, (doi: 10.1177/1098612X18809165) (PMID:30407137)

Awad, H., Al-Hamidhi, S., El Hussein, A.-R. M., Yousif, Y. M. z., Taha, K. M., Salih, D. A., Weir, W. and Babiker, H. (2018) Theileria lestoquardi in Sudan is highly diverse and genetically distinct from that in Oman. Infection, Genetics and Evolution, 62, pp. 46-52. (doi: 10.1016/j.meegid.2018.04.014) (PMID:29660557)

Ascencio, M. E., Florin-Christensen, M., Mamoun, C. B., Weir, W. , Shiels, B. and Schnittger, L. (2018) Cysteine proteinase C1A paralog profiles correspond with phylogenetic lineages of pathogenic piroplasmids. Veterinary Sciences, 5(2), 41. (doi: 10.3390/vetsci5020041) (PMID:29673170) (PMCID:PMC6024612)

Hemmink, J. D., Sitt, T., Pelle, R., de Klerk-Lorist, L.-M., Shiels, B. , Toye, P. G., Morrison, W. I. and Weir, W. (2018) Ancient diversity and geographical sub-structuring in African buffalo Theileria parva populations revealed through metagenetic analysis of antigen-encoding loci. International Journal for Parasitology, 48, pp. 287-296. (doi: 10.1016/j.ijpara.2017.10.006) (PMID:29408266) (PMCID:PMC5854372)

2017

Terron-Canedo, N., Weir, W. , Nicolson, L., Britton, C. and Nasir, L. (2017) Differential expression of microRNAs in bovine papillomavirus type 1 transformed equine cells. Veterinary and Comparative Oncology, 15(3), pp. 764-774. (doi: 10.1111/vco.12216) (PMID:27039895)

Coultous, R. M., Raftery, A. G. , Shiels, B. R. , Sutton, D. G.M. and Weir, W. (2017) Molecular confirmation of Sarcocystis fayeri in a donkey. Veterinary Parasitology, 240, pp. 30-33. (doi: 10.1016/j.vetpar.2017.04.026) (PMID:28576341)

Lempereur, L. et al. (2017) Identification of candidate transmission-blocking antigen genes in Theileria annulata and related vector-borne apicomplexan parasites. BMC Genomics, 18(1), 438. (doi: 10.1186/s12864-017-3788-1) (PMID:28583072) (PMCID:PMC5460460)

Cooper, A. et al. (2017) APOL1 renal risk variants have contrasting resistance and susceptibility associations with African trypanosomiasis. eLife, 6, e25461. (doi: 10.7554/eLife.25461) (PMID:28537557) (PMCID:PMC5495568)

Bilgic, H. B., Bakırcı, S., Kose, O., Unlu, A. H., Hacılarlıoglu, S., Eren, H., Weir, W. and Karagenc, T. (2017) Prevalence of tick-borne haemoparasites in small ruminants in Turkey and diagnostic sensitivity of single-PCR and RLB. Parasites and Vectors, 10, 211. (doi: 10.1186/s13071-017-2151-3) (PMID:28449722) (PMCID:PMC5408456)

Coultous, R., Weir, W. and Sutton, D. (2017) Equine piroplasmosis study. Veterinary Record, 180(10), p. 258. (doi: 10.1136/vr.j1153) (PMID:28283642)

Lee, S. M., Williamson, K., Weir, W. , Hulme-Moir, L. and Haining, H. (2017) Use of hyaluronidase in the comparison between manual and automated hematology analysis with the ADVIA 120 to improve analysis of feline body cavity effusions. Journal of Veterinary Diagnostic Investigation, 29(2), pp. 212-216. (doi: 10.1177/1040638716685133) (PMID:28064834)

Bilgiç, H. B., Ünlü, A. H., Aksulu, A., Bakırcı, S., Hacılarlıoğlu, S., Eren, H., Weir, W. and Karagenç, T. (2017) Selection of genetic markers to determine diversity in Theileria annulata populations after recombination. Turkiye Parazitologi Dergisi = Turkish Journal of Parasitology, 41(1), pp. 9-18. (doi: 10.5152/tpd.2017.4970) (PMID:28483728)

Kinnaird, J. H., Singh, M., Gillan, V. , Weir, W. , Calder, E. D.D., Hostettler, I., Tatu, U., Devaney, E. and Shiels, B. R. (2017) Characterization of HSP90 isoforms in transformed bovine leukocytes infected with Theileria annulata. Cellular Microbiology, 19(3), e12669. (doi: 10.1111/cmi.12669) (PMID:27649068) (PMCID:PMC5333456)

Bilgiç, H. B., Karagenç, T., Bakirci, S., Eren, H. and Weir, W. (2017) Loop mediated isothermal amplification (LAMP) of Theileria annulata DNA. Ankara Üniversitesi Veteriner Fakültesi Dergisi, 64(3), pp. 211-221. (doi: 10.1501/Vetfak_0000002801)

Gu, H. Y., Marks, N. D., Winter, A. D., Weir, W. , Tzelos, T., McNeilly, T. N., Britton, C. and Devaney, E. (2017) Conservation of a microRNA cluster in parasitic nematodes and profiling of miRNAs in excretory-secretory products and microvesicles of Haemonchus contortus. PLoS Neglected Tropical Diseases, 11(11), e0006056. (doi: 10.1371/journal.pntd.0006056) (PMID:29145392) (PMCID:PMC5709059)

2016

Goh, S. et al. (2016) Identification of Theileria lestoquardi antigens recognized by CD8+ T cells. PLoS ONE, 11(9), e0162571. (doi: 10.1371/journal.pone.0162571) (PMID:27611868) (PMCID:PMC5017765)

Al-Hamidhi, S., Weir, W. , Kinnaird, J., Tageledin, M., Beja-Pereira, A., Morrison, I., Thompson, J., Tait, A., Shiels, B. and Babiker, H. A. (2016) Theileria lestoquardi displays reduced genetic diversity relative to sympatric Theileria annulata in Oman. Infection, Genetics and Evolution, 43, pp. 297-306. (doi: 10.1016/j.meegid.2016.05.007) (PMID:27166095)

Capewell, P. et al. (2016) The skin is a significant but overlooked anatomical reservoir for vector-borne African trypanosomes. eLife, 5, e17716. (doi: 10.7554/eLife.17716) (PMID:27653219) (PMCID:PMC5065312)

Cooper, A., Capewell, P. , Clucas, C. , Veitch, N. , Weir, W. , Thomson, R., Raper, J. and MacLeod, A. (2016) A primate APOL1 variant that kills Trypanosoma brucei gambiense. PLoS Neglected Tropical Diseases, 10(8), e0004903. (doi: 10.1371/journal.pntd.0004903) (PMID:27494254) (PMCID:PMC4975595)

Gomes, J., Salgueiro, P., Inácio, J., Amaro, A., Pinto, J., Tait, A., Shiels, B. , Pereira da Fonseca, I., Santos-Gomes, G. and Weir, W. (2016) Population diversity of Theileria annulata in Portugal. Infection, Genetics and Evolution, 42, pp. 14-19. (doi: 10.1016/j.meegid.2016.04.023) (PMID:27109468)

Hemmink, J. D., Weir, W. , MacHugh, N. D., Graham, S. P., Patel, E., Paxton, E., Shiels, B. , Toye, P. G., Morrison, W. I. and Pelle, R. (2016) Limited genetic and antigenic diversity within parasite isolates used in a live vaccine against Theileria parva. International Journal for Parasitology, 46(8), pp. 495-506. (doi: 10.1016/j.ijpara.2016.02.007) (PMID:27080723) (PMCID:PMC4935670)

Bilgic, H. B., Karagenc, T., Bakırc, S., Shiels, B. , Tait, A., Kinnaird, J., Eren, H. and Weir, W. (2016) Identification and analysis of immunodominant antigens for ELISA-based detection of Theileria annulata. PLoS ONE, 11(6), e0156645. (doi: 10.1371/journal.pone.0156645) (PMID:27270235) (PMCID:PMC4896419)

Patakas, A., Ji, R., Weir, W. , Connolly, S. E., Benson, R. A. , Nadler, S. G., Brewer, J. M. , McInnes, I. B. and Garside, P. (2016) Abatacept inhibits T cell priming by inducing of a unique transcriptional profile that reduces their ability to activate antigen presenting cells. Arthritis and Rheumatology, 68(3), pp. 627-638. (doi: 10.1002/art.39470) (PMID:26473409)

Carletti, T., Barreto, C., Mesplet, M., Mira, A., Weir, W. , Shiels, B. , Oliva, A. G., Schnittger, L. and Florin-Christensen, M. (2016) Characterization of a papain-like cysteine protease essential for the survival of Babesia ovis merozoites. Ticks and Tick-borne Diseases, 7(1), pp. 85-93. (doi: 10.1016/j.ttbdis.2015.09.002) (PMID:26456355)

Weir, W. et al. (2016) Population genomics reveals the origin and asexual evolution of human infective trypanosomes. eLife, 5, e11473. (doi: 10.7554/eLife.11473) (PMID:26809473) (PMCID:PMC4739771)

2015

Bishop, R.P., Hemmink, J.D., Morrison, W.I., Weir, W. , Toye, P.G., Sitt, T., Spooner, P.R., Musoke, A.J., Skilton, R.A. and Odongo, D.O. (2015) The African buffalo parasite Theileria. sp. (buffalo) can infect and immortalize cattle leukocytes and encodes divergent orthologues of Theileria parva antigen genes. International Journal for Parasitology: Parasites and Wildlife, 4(3), pp. 333-342. (doi: 10.1016/j.ijppaw.2015.08.006) (PMID:26543804) (PMCID:PMC4589832)

Pieszko, M., Weir, W. , Goodhead, I., Kinnaird, J. and Shiels, B. (2015) ApiAP2 factors as candidate regulators of stochastic commitment to merozoite production in Theileria annulata. PLoS Neglected Tropical Diseases, 9(8), e0003933. (doi: 10.1371/journal.pntd.0003933) (PMID:26273826) (PMCID:PMC4537280)

Capewell, P. , Cooper, A., Clucas, C. , Weir, W. and MacLeod, A. (2015) A co-evolutionary arms race: trypanosomes shaping the human genome, humans shaping the trypanosome genome. Parasitology, 142(S1), S108-S119. (doi: 10.1017/S0031182014000602) (PMID:25656360) (PMCID:PMC4413828)

Al-Hamidhi, S. et al. (2015) Genetic diversity and population structure of Theileria annulata in Oman. PLoS ONE, 10(10), e0139581. (doi: 10.1371/journal.pone.0139581) (PMID:26469349) (PMCID:PMC4607491)

Capewell, P. , Cooper, A., Clucas, C. , Weir, W. , Vaikkinen, H., Morrison, L., Tait, A. and MacLeod, A. (2015) Exploiting genetic variation to discover genes involved in important disease phenotypes. Methods in Molecular Biology, 1201, pp. 91-107. (doi: 10.1007/978-1-4939-1438-8_5) (PMID:25388109)

Winter, A. D. et al. (2015) A novel member of the let-7 microRNA family is associated with developmental transitions in filarial nematode parasites. BMC Genomics, 16, 331. (doi: 10.1186/s12864-015-1536-y) (PMID:25896062) (PMCID:PMC4428239)

Woolhouse, M. E. J. et al. (2015) Co-infections determine patterns of mortality in a population exposed to parasite infection. Science Advances, 1(2), e1400026. (doi: 10.1126/sciadv.1400026) (PMID:26601143) (PMCID:PMC4643819)

2014

Jackson, A. P. et al. (2014) The evolutionary dynamics of variant antigen genes in Babesia reveal a history of genomic innovation underlying host-parasite interaction. Nucleic Acids Research, 42(11), pp. 7113-7131. (doi: 10.1093/nar/gku322) (PMID:24799432) (PMCID:PMC4066756)

2013

Braceland, M., Bickerdike, R., Tinsley, J., Cockerill, D., Mcloughlin, M.F., Graham, D.A., Burchmore, R.J., Weir, W. , Wallace, C. and Eckersall, P.D. (2013) The serum proteome of Atlantic salmon, Salmo salar, during pancreas disease (PD) following infection with salmonid alphavirus subtype 3 (SAV3). Journal of Proteomics, 94, pp. 423-436. (doi: 10.1016/j.jprot.2013.10.016) (PMID:24145143) (PMCID:PMC3878379)

Capewell, P. , Clucas, C. , Weir, W. , Veitch, N. and MacLeod, A. (2013) Normal human serum lysis of non-human trypanosomes and resistance of T. b. rhodesiense and T. b. gambiense. In: Magez, S. and Radwanska, M. (eds.) Trypanosomes and Trypanosomiasis. Springer, pp. 139-160. ISBN 9783709115558 (doi: 10.1007/978-3-7091-1556-5_6)

Asiimwe, B.B., Weir, W. , Tait, A., Lubega, G.W. and Oura, C.A.L. (2013) Haemoparasite infection kinetics and the population structure of Theileria parva on a single farm in Uganda. Veterinary Parasitology, 193(1-3), pp. 8-14. (doi: 10.1016/j.vetpar.2012.12.017)

Bilgiç, H. B., Karagenç, T., Simuunza, M., Shiels, B. , Tait, A., Eren, H. and Weir, W. (2013) Development of a multiplex PCR assay for simultaneous detection of Theileria annulata, Babesia bovis and Anaplasma marginale in cattle. Experimental Parasitology, 133(2), pp. 222-229. (doi: 10.1016/j.exppara.2012.11.005) (PMID:23183165) (PMCID:PMC3650576)

Capewell, P. , Clucas, C. , DeJesus, E., Kieft, R., Hajduk, S., Veitch, N. , Steketee, P.C., Cooper, A., Weir, W. and MacLeod, A. (2013) The TgsGP gene is essential for resistance to human serum in Trypanosoma brucei gambiense. PLoS Pathogens, 9(10), e1003686. (doi: 10.1371/journal.ppat.1003686) (PMID:24098129) (PMCID:PMC3789759)

Hayashida, K., Abe, T., Weir, W. , Nakao, R., Ito, K., Kajino, K., Suzuki, Y., Jongejan, F., Geysen, D. and Sugimoto, C. (2013) Whole-genome sequencing of Theileria parva strains provides insight into parasite migration and diversification in the african continent. DNA Research, 20(3), pp. 209-220. (doi: 10.1093/dnares/dst003)

Kinnaird, J.H., Weir, W. , Durrani, Z., Pillai, S.S., Baird, M. and Shiels, B.R. (2013) A bovine lymphosarcoma cell line infected with theileria annulata exhibits an irreversible reconfiguration of host cell gene expression. PLoS ONE, 8(6), e66833. (doi: 10.1371/journal.pone.0066833) (PMID:23840536) (PMCID:PMC3694138)

2012

Hayashida, K. et al. (2012) Comparative genome analysis of three eukaryotic parasites with differing abilities to transform leukocytes reveals key mediators of Theileria-induced leukocyte transformation. mBio, 3(5), e00204-12. (doi: 10.1128/mBio.00204-12) (PMID:22951932) (PMCID:PMC3445966)

Durrani, Z., Weir, W. , Pillai, S., Kinnaird, J. and Shiels, B. (2012) Modulation of activation-associated host cell gene expression by the apicomplexan parasite Theileria annulata. Cellular Microbiology, 14(9), pp. 1434-1454. (doi: 10.1111/j.1462-5822.2012.01809.x) (PMID:22533473) (PMCID:PMC3532605)

Braceland, M., Bickerdike, R., Cockerill, D., Burchmore, R. , Weir, W. and Eckersall, D. (2012) Proteomics in biomarker detection and monitoring of pancreas disease (PD) in atlantic salmon (Salmo salar). In: 3rd Managing Committee Meeting and 2nd Meeting of Working Groups 1, 2 & 3 of COST Action FA1002, Vilamoura, Portugal, 12-13 Apr 2012, pp. 87-90. ISBN 9789086861958 (doi: 10.3920/978-90-8686-751-6_20)

Winter, A.D., Weir, W. , Hunt, M., Berriman, M., Gilleard, J.S., Devaney, E. and Britton, C. (2012) Diversity in parasitic nematode genomes: the microRNAs of Brugia pahangi and Haemonchus contortus are largely novel. BMC Genomics, 13, p. 4. (doi: 10.1186/1471-2164-13-4)

2011

Oura, C.A.L., Tait, A., Asiimwe, B., Lubega, G.W. and Weir, W. (2011) Theileria parva genetic diversity and haemoparasite prevalence in cattle and wildlife in and around Lake Mburo National Park in Uganda. Parasitology Research, 108(6), pp. 1365-1374. (doi: 10.1007/s00436-010-2030-8)

Simuunza, M., Bilgic, H., Karagenc, T., Syakalima, M., Shiels, B. , Tait, A. and Weir, W. (2011) Population genetic analysis and sub-structuring in Babesia bovis. Molecular and Biochemical Parasitology, 177(2), pp. 106-115. (doi: 10.1016/j.molbiopara.2011.02.002) (PMID:21316400)

Connelley, T.K., MacHugh, N.D., Pelle, R., Weir, W. and Morrison, W.I. (2011) Escape from CD8⁺ T cell response by natural variants of an immunodominant epitope from Theileria parva is predominantly due to loss of TCR recognition. Journal of Immunology, 187(11), pp. 5910-5920. (doi: 10.4049/jimmunol.1102009)

Gharbi, M. et al. (2011) Prime-boost immunisation against tropical theileriosis with two parasite surface antigens: Evidence for protection and antigen synergy. Vaccine, 29(38), pp. 6620-6628. (doi: 10.1016/j.vaccine.2011.06.109) (PMID:21762754)

MacHugh, N. D., Weir, W. , Burrells, A., Lizundia, R., Graham, S.P., Taracha, E.L., Shiels, B.R. , Langsley, G. and Morrison, W.I. (2011) Extensive polymorphism and evidence of immune selection in a highly dominant antigen recognized by bovine CD8 T cells specific for Theileria annulata. Infection and Immunity, 79(5), pp. 2059-2069. (doi: 10.1128/IAI.01285-10) (PMID:21300773) (PMCID:PMC3088144)

Oura, C.A.L., Tait, A., Asiimwe, B., Lubega, G.W. and Weir, W. (2011) Haemoparasite prevalence and Theileria parva strain diversity in Cape buffalo (Syncerus caffer) in Uganda. Veterinary Parasitology, 175(3-4), pp. 212-219. (doi: 10.1016/j.vetpar.2010.10.032)

Pelle, R. et al. (2011) Two Theileria parva CD8 T cell antigen genes are more variable in buffalo than cattle parasites, but differ in pattern of sequence diversity. PLoS ONE, 6(4), e19015. (doi: 10.1371/journal.pone.0019015)

Simuunza, M., Weir, W. , Courcier, E., Tait, A. and Shiels, B. (2011) Epidemiological analysis of tick-borne diseases in Zambia. Veterinary Parasitology, 175(3-4), pp. 331-342. (doi: 10.1016/j.vetpar.2010.09.027) (PMID:21106294)

Weir, W. , Karagenç, T., Gharbi, M., Simuunza, M., Aypak, S., Aysul, N., Darghouth, M. A., Shiels, B. and Tait, A. (2011) Population diversity and multiplicity of infection in Theileria annulata. International Journal for Parasitology, 41(2), pp. 193-203. (doi: 10.1016/j.ijpara.2010.08.004) (PMID:20833170) (PMCID:PMC3034872)

2010

Schmuckli-Maurer, J., Kinnaird, J., Pillai, S., Hermann, P., McKellar, S., Weir, W. , Dobbelaere, D. and Shiels, B. (2010) Modulation of NF-kappaB activation in Theileria annulata-infected cloned cell lines is associated with detection of parasite-dependent IKK signalosomes and disruption of the actin cytoskeleton. Cellular Microbiology, 12(2), pp. 158-173. (doi: 10.1111/j.1462-5822.2009.01386.x) (PMID:19804486)

Bilgic, H.B., Karagenç, T., Shiels, B. , Tait, A., Eren, H. and Weir, W. (2010) Evaluation of cytochrome b as a sensitive target for PCR based detection of T. annulata carrier animals. Veterinary Parasitology, 174(3-4), pp. 341-347. (doi: 10.1016/j.vetpar.2010.08.025) (PMID:20880635)

Chaussepied, M. et al. (2010) TGF-b2 induction regulates invasiveness of theileria-transformed leukocytes and disease susceptibility. PLoS Pathogens, 6(11), e1001197. (doi: 10.1371/journal.ppat.1001197) (PMID:21124992) (PMCID:PMC2987823)

Weir, W., Karagenç, T., Baird, M., Tait, A. and Shiels, B.R. (2010) Evolution and diversity of secretome genes in the apicomplexan parasite Theileria annulata. BMC Genomics, 11, p. 42. (doi: 10.1186/1471-2164-11-42) (PMID:20082698) (PMCID:PMC2826314)

2009

Weir, W., Sunter, J., Chaussepied, M., Skilton, R., Tait, A., de Villiers, E.P., Bishop, R., Shiels, B. and Langsley, G. (2009) Highly syntenic and yet divergent: a tale of two Theilerias. Infection, Genetics and Evolution, 9(4), pp. 453-461. (doi: 10.1016/j.meegid.2009.01.002) (PMID:19460310)

Beck, H.P. et al. (2009) Molecular approaches to diversity of populations of apicomplexan parasites. International Journal for Parasitology, 39(2), pp. 175-189. (doi: 10.1016/j.ijpara.2008.10.001) (PMID:18983997)

Sajid, M. et al. (2009) Proteases of parasitic protozoa - current status and validation. In: Selzer, P.M. (ed.) Antiparasitic and Antibacterial Drug Discovery: From Molecular Targets to Drug Candidates. Series: Drug discovery in infectious diseases. Wiley-VCH: Weinheim, Germany, pp. 177-210. ISBN 9783527626823

2007

Weir, W. , Ben-Miled, L., Karagenc, T., Katzer, F., Darghouth, M., Shiels, B. and Tait, A. (2007) Genetic exchange and sub-structuring in Theileria annulata populations. Molecular and Biochemical Parasitology, 154(2), pp. 170-180. (doi: 10.1016/j.molbiopara.2007.04.015) (PMID:17540465)

2006

Shiels, B. , Langsley, G., Weir, W. , Pain, A., McKellar, S. and Dobbelaere, D. (2006) Alteration of host cell phenotype by Theileria annulata and Theileria parva: mining for manipulators in the parasite genomes. International Journal for Parasitology, 36(1), pp. 9-21. (doi: 10.1016/j.ijpara.2005.09.002) (PMID:16221473)

2005

Oura, C.A.L., Asiimwe, B.B., Weir, W. , Lubega, G.W. and Tait, A. (2005) Population genetic analysis and sub-structuring of Theileria parva in Uganda. Molecular and Biochemical Parasitology, 140(2), pp. 229-239. (doi: 10.1016/j.molbiopara.2004.12.015)

Pain, A. et al. (2005) Genome of the host-cell transforming parasite Theileria annulata compared with T-parva. Science, 309, pp. 131-133. (doi: 10.1126/science.1110418) (PMID:15994557)

2003

Smith, H.V., Nichols, R.A.B., Weir, W. , Mallon, M., Macleod, A., Wastling, J.M., Reilly, W.J. and Tait, A. (2003) Molecular investigations into waterborne outbreaks, incidents and events involving Cryptosporidium contamination. In: Latham, S.M., Smith, H.V. and Wastling, J.M. (eds.) Workshop on the Application of Genetic Fingerprinting for the Monitoring of Cryptosporidium in Humans, Animals and the Environment: Boulder, Colorado, USA, 3rd-5th August 2003. Foundation for Water Research (FWR): Marlow, Buckinghamshire, UK, pp. 85-90. ISBN 9780952171256

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