Dr Lesley Gilmour
- Research Portfolio Manager (MVLS College Senior Management)
telephone:
330 3597
email:
Lesley.Gilmour@glasgow.ac.uk
Biological Services, Veterinary Research Facility, Garscube Estate, Glasgow, G61 1QH
Publications
2024
Derby, S. et al. (2024) Inhibition of ATR opposes glioblastoma invasion through disruption of cytoskeletal networks and integrin internalisation via macropinocytosis. Neuro-Oncology, (doi: 10.1093/neuonc/noad210) (PMID:37936324) (Early Online Publication)
2021
Birch, J. et al. (2021) Inhibition of ATR prevents macropinocytosis driven retraction of neurites and opposes invasion in GBM. Research Square, (doi: 10.21203/rs.3.rs-967109/v1) (PMID:37936324)
2018
Birch, J. L. et al. (2018) A novel small-molecule inhibitor of MRCK prevents radiation-driven invasion in glioblastoma. Cancer Research, 78(22), pp. 6509-6522. (doi: 10.1158/0008-5472.CAN-18-1697) (PMID:30279244)
Carruthers, R. D. et al. (2018) Replication stress drives constitutive activation of the DNA damage response and radioresistance in glioblastoma stem-like cells. Cancer Research, 78(17), pp. 5060-5071. (doi: 10.1158/0008-5472.CAN-18-0569) (PMID:29976574) (PMCID:PMC6128404)
Holmes, W. M. , Vallatos, A. , Gilmour, L. and Chalmers, A. J. (2018) Multiple boli arterial spin labelling for high signal-to-noise rodent brain perfusion imaging. Magnetic Resonance in Medicine, 79(2), pp. 1020-1030. (doi: 10.1002/mrm.26706) (PMID:28516482)
2017
Gomez-Roman, N. , Stevenson, K., Gilmour, L., Hamilton, G. and Chalmers, A. (2017) A novel 3D human glioblastoma cell culture system for modeling drug and radiation responses. Neuro-Oncology, 19(2), pp. 229-241. (doi: 10.1093/neuonc/now164) (PMID:27576873) (PMCID:PMC5463789)
2016
Lochhead, P. A., Clark, J., Wang, L.-Z., Gilmour, L., Squires, M., Gilley, R., Foxton, C., Newell, D. R., Wedge, S. R. and Cook, S. J. (2016) Tumor cells with KRAS or BRAF mutations orERK5/MAPK7 amplification are not addicted to ERK5 activity for cell proliferation. Cell Cycle, 15(4), pp. 506-518. (doi: 10.1080/15384101.2015.1120915) (PMID:26959608)
2015
Ahmed, S., Carruthers, R. , Gilmour, L., Yildirim, S., Watts, C. and Chalmers, A. (2015) Selective inhibition of parallel DNA damage response pathways optimizes radiosensitization of glioblastoma stem-like cells. Cancer Research, 75(20), pp. 4416-4428. (doi: 10.1158/0008-5472.can-14-3790) (PMID:26282173)
2014
Yahyanejad, S., Granton, P. V., Lieuwes, N. G., Gilmour, L., Dubois, L., Theys, J., Chalmers, A. J. , Verhaegen, F. and Vooijs, M. (2014) Complementary use of bioluminescence imaging and contrast-enhanced micro-computed tomography in an orthotopic brain tumor model. Molecular imaging, 13, pp. 1-8. (PMID:25743108)
2011
Gillies, R.M., Robinson, S.P., McPhail, L.D., Carter, N.D. and Murray, J.F. (2011) Immunohistochemical assessment of intrinsic and extrinsic markers of hypoxia in reproductive tissue: differential expression of HIF1α and HIF2α in rat oviduct and endometrium. Journal of Molecular Histology, 42(4), pp. 341-354. (doi: 10.1007/s10735-011-9338-2)
Articles
Derby, S. et al. (2024) Inhibition of ATR opposes glioblastoma invasion through disruption of cytoskeletal networks and integrin internalisation via macropinocytosis. Neuro-Oncology, (doi: 10.1093/neuonc/noad210) (PMID:37936324) (Early Online Publication)
Birch, J. et al. (2021) Inhibition of ATR prevents macropinocytosis driven retraction of neurites and opposes invasion in GBM. Research Square, (doi: 10.21203/rs.3.rs-967109/v1) (PMID:37936324)
Birch, J. L. et al. (2018) A novel small-molecule inhibitor of MRCK prevents radiation-driven invasion in glioblastoma. Cancer Research, 78(22), pp. 6509-6522. (doi: 10.1158/0008-5472.CAN-18-1697) (PMID:30279244)
Carruthers, R. D. et al. (2018) Replication stress drives constitutive activation of the DNA damage response and radioresistance in glioblastoma stem-like cells. Cancer Research, 78(17), pp. 5060-5071. (doi: 10.1158/0008-5472.CAN-18-0569) (PMID:29976574) (PMCID:PMC6128404)
Holmes, W. M. , Vallatos, A. , Gilmour, L. and Chalmers, A. J. (2018) Multiple boli arterial spin labelling for high signal-to-noise rodent brain perfusion imaging. Magnetic Resonance in Medicine, 79(2), pp. 1020-1030. (doi: 10.1002/mrm.26706) (PMID:28516482)
Gomez-Roman, N. , Stevenson, K., Gilmour, L., Hamilton, G. and Chalmers, A. (2017) A novel 3D human glioblastoma cell culture system for modeling drug and radiation responses. Neuro-Oncology, 19(2), pp. 229-241. (doi: 10.1093/neuonc/now164) (PMID:27576873) (PMCID:PMC5463789)
Lochhead, P. A., Clark, J., Wang, L.-Z., Gilmour, L., Squires, M., Gilley, R., Foxton, C., Newell, D. R., Wedge, S. R. and Cook, S. J. (2016) Tumor cells with KRAS or BRAF mutations orERK5/MAPK7 amplification are not addicted to ERK5 activity for cell proliferation. Cell Cycle, 15(4), pp. 506-518. (doi: 10.1080/15384101.2015.1120915) (PMID:26959608)
Ahmed, S., Carruthers, R. , Gilmour, L., Yildirim, S., Watts, C. and Chalmers, A. (2015) Selective inhibition of parallel DNA damage response pathways optimizes radiosensitization of glioblastoma stem-like cells. Cancer Research, 75(20), pp. 4416-4428. (doi: 10.1158/0008-5472.can-14-3790) (PMID:26282173)
Yahyanejad, S., Granton, P. V., Lieuwes, N. G., Gilmour, L., Dubois, L., Theys, J., Chalmers, A. J. , Verhaegen, F. and Vooijs, M. (2014) Complementary use of bioluminescence imaging and contrast-enhanced micro-computed tomography in an orthotopic brain tumor model. Molecular imaging, 13, pp. 1-8. (PMID:25743108)
Gillies, R.M., Robinson, S.P., McPhail, L.D., Carter, N.D. and Murray, J.F. (2011) Immunohistochemical assessment of intrinsic and extrinsic markers of hypoxia in reproductive tissue: differential expression of HIF1α and HIF2α in rat oviduct and endometrium. Journal of Molecular Histology, 42(4), pp. 341-354. (doi: 10.1007/s10735-011-9338-2)