Dr Gavin Blackburn
- Mass Spectrometry Technical Lead (MVLS Research Facilities)
email:
Gavin.Blackburn@glasgow.ac.uk
Room B3.08, Joseph Black Building, GUniversity of Glasgow, University Place, G12 8QQ
Publications
2025
Twesigomwe, David, Zdesenko, Grace, Mduluza, Takafira, Blackburn, Gavin ORCID: https://orcid.org/0000-0003-1037-6012, Burchmore, Richard
ORCID: https://orcid.org/0000-0003-1663-9004 and Mutapi, Francisca
(2025)
Microsampling with dried blood spots and mass spectrometry enables PK/PD profiling of responses to praziquantel in a Schistosoma haematobium–exposed Zimbabwean population.
Pharmacogenetics and Genomics, 35(7),
pp. 197-213.
(doi: 10.1097/FPC.0000000000000572)
(PMID:40512603)
McCreath, Gordan, Regnault, Clément, Blackburn, Gavin J. ORCID: https://orcid.org/0000-0003-1037-6012, Daly, Rónán
ORCID: https://orcid.org/0000-0002-1275-6820, Leanord, Alistair T., Whitfield, Phillip D.
ORCID: https://orcid.org/0000-0002-0814-4119, Roe, Andrew J.
ORCID: https://orcid.org/0000-0003-3698-6134, Davidson, Alan, Watson, Malcolm J. and Sim, Malcolm A. B.
(2025)
Metabolomics for the diagnosis of secondary infections in critically ill patients with COVID-19.
Critical Care Explorations,
(Accepted for Publication)
Campillo Poveda, M. et al. (2025) Metabolomic and functional analyses of small molecules secreted by intestinal nematodes in the activation of epithelial tuft cells. Metabolomics, 21(3), 55. (doi: 10.1007/s11306-025-02248-w) (PMID:40257648) (PMCID:PMC12011944)
2024
Gabaldón-Figueira, J. C. et al. (2024) Changes in lipid abundance are associated with disease progression and treatment response in chronic Trypanosoma cruzi infection. Parasites and Vectors, 17(1), 459. (doi: 10.1186/s13071-024-06548-3) (PMID:39521974) (PMCID:PMC11549750)
2023
Ross, E. A. et al. (2023) Nanotopography reveals metabolites that maintain the immunomodulatory phenotype of mesenchymal stromal cells. Nature Communications, 14, 753. (doi: 10.1038/s41467-023-36293-7) (PMID:36765065) (PMCID:PMC9918539)
2022
Raposo de Magalhães, Cláudia, Farinha, Ana Paula, Blackburn, Gavin ORCID: https://orcid.org/0000-0003-1037-6012, Whitfield, Phillip D.
ORCID: https://orcid.org/0000-0002-0814-4119, Carrilho, Raquel, Schrama, Denise, Cerqueira, Marco and Rodrigues, Pedro M
(2022)
Gilthead seabream liver integrative proteomics and metabolomics analysis reveals regulation by different prosurvival pathways in the metabolic adaptation to stress.
International Journal of Molecular Sciences, 23(23),
15395.
(doi: 10.3390/ijms232315395)
(PMID:36499720)
(PMCID:PMC9741202)
O'Brien, Á. C. et al. (2022) Using organic contaminants to constrain the terrestrial journey of the martian meteorite Lafayette. Astrobiology, 22(11), pp. 1351-1362. (doi: 10.1089/ast.2021.0180) (PMID:36264546) (PMCID:PMC9618387)
Dominoni, D. M. et al. (2022) Integrated molecular and behavioural data reveal deep circadian disruption in response to artificial light at night in male Great tits (Parus major). Scientific Reports, 12, 1553. (doi: 10.1038/s41598-022-05059-4) (PMID:35091579) (PMCID:PMC8799718)
2021
Rossitto, G. et al. (2021) High sodium intake, glomerular hyperfiltration and protein catabolism in patients with essential hypertension. Cardiovascular Research, 117(5), pp. 1372-1381. (doi: 10.1093/cvr/cvaa205) (PMID:33053160) (PMCID:PMC8064429)
Biddau, M. et al. (2021) Plasmodium falciparum LipB mutants display altered redox and carbon metabolism in asexual stages and cannot complete sporogony in Anopheles mosquitoes. International Journal for Parasitology, 51(6), pp. 441-453. (doi: 10.1016/j.ijpara.2020.10.011) (PMID:33713652) (PMCID:PMC8126644)
2020
Blackburn, G. et al. (2020) Running on empty: a metabolomics approach to investigating changing energy metabolism during fasted exercise and rest. Metabolites, 10(10), 399. (doi: 10.3390/metabo10100399) (PMID:33050077) (PMCID:PMC7600507)
Daly, R. et al. (2020) Changes in plasma itaconate elevation in early rheumatoid arthritis patients elucidates disease activity associated macrophage activation. Metabolites, 10(6), 241. (doi: 10.3390/metabo10060241) (PMID:32531990) (PMCID:PMC7344783)
2018
Alghamdi, Adel, Gerasimidis, Konstantinos ORCID: https://orcid.org/0000-0001-9432-2200, Blackburn, Gavin
ORCID: https://orcid.org/0000-0003-1037-6012, Akinci, Didem, Edwards, Christine
ORCID: https://orcid.org/0000-0003-0406-918X, Russell, Richard K. and Watson, David G.
(2018)
Untargeted metabolomics of extracts from faecal samples demonstrates distinct differences between paediatric Crohn’s disease patients and healthy controls but no significant changes resulting from exclusive enteral nutrition treatment.
Metabolites, 8(4),
82.
(doi: 10.3390/metabo8040082)
(PMID:30467282)
2017
Westrop, Gareth D., Wang, Lijie, Blackburn, Gavin J. ORCID: https://orcid.org/0000-0003-1037-6012, Zhang, Tong, Zheng, Liang, Watson, David G. and Coombs, Graham H.
(2017)
Metabolomic profiling and stable isotope labelling of Trichomonas vaginalis and Tritrichomonas foetus reveal major differences in amino acid metabolism including the production of 2-hydroxyisocaproic acid, cystathionine and S-methylcysteine.
PLoS ONE, 12(12),
e0189072.
(doi: 10.1371/journal.pone.0189072)
(PMID:29267346)
(PMCID:PMC5739422)
Alwashih, Mohammad A., Watson, David G., Andrew, Ruth, Stimson, Roland H., Alossaimi, Manal, Blackburn, Gavin ORCID: https://orcid.org/0000-0003-1037-6012 and Walker, Brian R.
(2017)
Plasma metabolomic profile varies with glucocorticoid dose in patients with congenital adrenal hyperplasia.
Scientific Reports, 7,
17092.
(doi: 10.1038/s41598-017-17220-5)
(PMID:29213133)
(PMCID:PMC5719028)
Tsimbouri, P. M. et al. (2017) Stimulation of 3D osteogenesis by mesenchymal stem cells using a nanovibrational bioreactor. Nature Biomedical Engineering, 1, pp. 758-770. (doi: 10.1038/s41551-017-0127-4) (PMID:31015671)
2016
Shaw, C.D. et al. (2016) In vitro selection of miltefosine resistance in promastigotes of Leishmania donovani from Nepal: genomic and metabolomic characterization. Molecular Microbiology, 99(6), pp. 1134-1148. (doi: 10.1111/mmi.13291) (PMID:26713880) (PMCID:PMC4832254)
2015
Daskalaki, Evangelia, Blackburn, Gavin ORCID: https://orcid.org/0000-0003-1037-6012, Kalna, Gabriela, Zhang, Tong, Anthony, Nahoum and Watson, David
(2015)
A study of the effects of exercise on the urinary metabolome using normalisation to individual metabolic output.
Metabolites, 5(1),
pp. 119-139.
(doi: 10.3390/metabo5010119)
(PMID:25734341)
(PMCID:PMC4381293)
Articles
Twesigomwe, David, Zdesenko, Grace, Mduluza, Takafira, Blackburn, Gavin ORCID: https://orcid.org/0000-0003-1037-6012, Burchmore, Richard
ORCID: https://orcid.org/0000-0003-1663-9004 and Mutapi, Francisca
(2025)
Microsampling with dried blood spots and mass spectrometry enables PK/PD profiling of responses to praziquantel in a Schistosoma haematobium–exposed Zimbabwean population.
Pharmacogenetics and Genomics, 35(7),
pp. 197-213.
(doi: 10.1097/FPC.0000000000000572)
(PMID:40512603)
McCreath, Gordan, Regnault, Clément, Blackburn, Gavin J. ORCID: https://orcid.org/0000-0003-1037-6012, Daly, Rónán
ORCID: https://orcid.org/0000-0002-1275-6820, Leanord, Alistair T., Whitfield, Phillip D.
ORCID: https://orcid.org/0000-0002-0814-4119, Roe, Andrew J.
ORCID: https://orcid.org/0000-0003-3698-6134, Davidson, Alan, Watson, Malcolm J. and Sim, Malcolm A. B.
(2025)
Metabolomics for the diagnosis of secondary infections in critically ill patients with COVID-19.
Critical Care Explorations,
(Accepted for Publication)
Campillo Poveda, M. et al. (2025) Metabolomic and functional analyses of small molecules secreted by intestinal nematodes in the activation of epithelial tuft cells. Metabolomics, 21(3), 55. (doi: 10.1007/s11306-025-02248-w) (PMID:40257648) (PMCID:PMC12011944)
Gabaldón-Figueira, J. C. et al. (2024) Changes in lipid abundance are associated with disease progression and treatment response in chronic Trypanosoma cruzi infection. Parasites and Vectors, 17(1), 459. (doi: 10.1186/s13071-024-06548-3) (PMID:39521974) (PMCID:PMC11549750)
Ross, E. A. et al. (2023) Nanotopography reveals metabolites that maintain the immunomodulatory phenotype of mesenchymal stromal cells. Nature Communications, 14, 753. (doi: 10.1038/s41467-023-36293-7) (PMID:36765065) (PMCID:PMC9918539)
Raposo de Magalhães, Cláudia, Farinha, Ana Paula, Blackburn, Gavin ORCID: https://orcid.org/0000-0003-1037-6012, Whitfield, Phillip D.
ORCID: https://orcid.org/0000-0002-0814-4119, Carrilho, Raquel, Schrama, Denise, Cerqueira, Marco and Rodrigues, Pedro M
(2022)
Gilthead seabream liver integrative proteomics and metabolomics analysis reveals regulation by different prosurvival pathways in the metabolic adaptation to stress.
International Journal of Molecular Sciences, 23(23),
15395.
(doi: 10.3390/ijms232315395)
(PMID:36499720)
(PMCID:PMC9741202)
O'Brien, Á. C. et al. (2022) Using organic contaminants to constrain the terrestrial journey of the martian meteorite Lafayette. Astrobiology, 22(11), pp. 1351-1362. (doi: 10.1089/ast.2021.0180) (PMID:36264546) (PMCID:PMC9618387)
Dominoni, D. M. et al. (2022) Integrated molecular and behavioural data reveal deep circadian disruption in response to artificial light at night in male Great tits (Parus major). Scientific Reports, 12, 1553. (doi: 10.1038/s41598-022-05059-4) (PMID:35091579) (PMCID:PMC8799718)
Rossitto, G. et al. (2021) High sodium intake, glomerular hyperfiltration and protein catabolism in patients with essential hypertension. Cardiovascular Research, 117(5), pp. 1372-1381. (doi: 10.1093/cvr/cvaa205) (PMID:33053160) (PMCID:PMC8064429)
Biddau, M. et al. (2021) Plasmodium falciparum LipB mutants display altered redox and carbon metabolism in asexual stages and cannot complete sporogony in Anopheles mosquitoes. International Journal for Parasitology, 51(6), pp. 441-453. (doi: 10.1016/j.ijpara.2020.10.011) (PMID:33713652) (PMCID:PMC8126644)
Blackburn, G. et al. (2020) Running on empty: a metabolomics approach to investigating changing energy metabolism during fasted exercise and rest. Metabolites, 10(10), 399. (doi: 10.3390/metabo10100399) (PMID:33050077) (PMCID:PMC7600507)
Daly, R. et al. (2020) Changes in plasma itaconate elevation in early rheumatoid arthritis patients elucidates disease activity associated macrophage activation. Metabolites, 10(6), 241. (doi: 10.3390/metabo10060241) (PMID:32531990) (PMCID:PMC7344783)
Alghamdi, Adel, Gerasimidis, Konstantinos ORCID: https://orcid.org/0000-0001-9432-2200, Blackburn, Gavin
ORCID: https://orcid.org/0000-0003-1037-6012, Akinci, Didem, Edwards, Christine
ORCID: https://orcid.org/0000-0003-0406-918X, Russell, Richard K. and Watson, David G.
(2018)
Untargeted metabolomics of extracts from faecal samples demonstrates distinct differences between paediatric Crohn’s disease patients and healthy controls but no significant changes resulting from exclusive enteral nutrition treatment.
Metabolites, 8(4),
82.
(doi: 10.3390/metabo8040082)
(PMID:30467282)
Westrop, Gareth D., Wang, Lijie, Blackburn, Gavin J. ORCID: https://orcid.org/0000-0003-1037-6012, Zhang, Tong, Zheng, Liang, Watson, David G. and Coombs, Graham H.
(2017)
Metabolomic profiling and stable isotope labelling of Trichomonas vaginalis and Tritrichomonas foetus reveal major differences in amino acid metabolism including the production of 2-hydroxyisocaproic acid, cystathionine and S-methylcysteine.
PLoS ONE, 12(12),
e0189072.
(doi: 10.1371/journal.pone.0189072)
(PMID:29267346)
(PMCID:PMC5739422)
Alwashih, Mohammad A., Watson, David G., Andrew, Ruth, Stimson, Roland H., Alossaimi, Manal, Blackburn, Gavin ORCID: https://orcid.org/0000-0003-1037-6012 and Walker, Brian R.
(2017)
Plasma metabolomic profile varies with glucocorticoid dose in patients with congenital adrenal hyperplasia.
Scientific Reports, 7,
17092.
(doi: 10.1038/s41598-017-17220-5)
(PMID:29213133)
(PMCID:PMC5719028)
Tsimbouri, P. M. et al. (2017) Stimulation of 3D osteogenesis by mesenchymal stem cells using a nanovibrational bioreactor. Nature Biomedical Engineering, 1, pp. 758-770. (doi: 10.1038/s41551-017-0127-4) (PMID:31015671)
Shaw, C.D. et al. (2016) In vitro selection of miltefosine resistance in promastigotes of Leishmania donovani from Nepal: genomic and metabolomic characterization. Molecular Microbiology, 99(6), pp. 1134-1148. (doi: 10.1111/mmi.13291) (PMID:26713880) (PMCID:PMC4832254)
Daskalaki, Evangelia, Blackburn, Gavin ORCID: https://orcid.org/0000-0003-1037-6012, Kalna, Gabriela, Zhang, Tong, Anthony, Nahoum and Watson, David
(2015)
A study of the effects of exercise on the urinary metabolome using normalisation to individual metabolic output.
Metabolites, 5(1),
pp. 119-139.
(doi: 10.3390/metabo5010119)
(PMID:25734341)
(PMCID:PMC4381293)
Research datasets
2017
Tsimbouri, P. , Childs, P., Pemberton, G. D., Yang, J., Jayawarna, V., Orapiriyakul, W., Burgess, K., Gonzalez-Garcia, C., Blackburn, G., Thomas, D., Giraldo, C. V., Biggs, M. J. P., Curtis, A., Salmerón-Sanchez, M., Reid, S. and Dalby, M. (2017) Stimulation of 3D osteogenesis by mesenchymal stem cells via a nanovibrational bioreactor. [Data Collection]