Dr Elaine Huston

  • Lecturer (Molecular Biosciences)

telephone: 01413302858
email: Elaine.Huston@glasgow.ac.uk

R414, Davidson Building, Glasgow G12 8QQ

Import to contacts

ORCID iDhttps://orcid.org/0009-0001-6978-7134

Research interests

Research groups

Publications

List by: Type | Date

Jump to: 2017 | 2015 | 2014 | 2013 | 2011 | 2010 | 2009 | 2008
Number of items: 12.

2017

Tanaka, M. et al. (2017) Aggregation of scaffolding protein DISC1 dysregulates phosphodiesterase 4 in Huntington’s disease. Journal of Clinical Investigation, 127(4), pp. 1438-1450. (doi: 10.1172/JCI85594) (PMID:28263187)

2015

DeLeeuw, J., Weir, Jane, Copsey, Dickon, Roden, Chris, Deeley, Susan ORCID logoORCID: https://orcid.org/0000-0002-6712-3908, Huston, Elaine ORCID logoORCID: https://orcid.org/0009-0001-6978-7134, McVey, Mary ORCID logoORCID: https://orcid.org/0000-0003-3740-6023 and Finlay, Chris ORCID logoORCID: https://orcid.org/0000-0001-6079-1199 (2015) Developing Graduate Attributes and Improving Student Employability Through Work-based Learning: Opportunities, Successes and Challenges. 8th Annual University of Glasgow Learning and Teaching Conference, Glasgow, UK, 14 Apr 2015.

2014

Sheppard, C. L. et al. (2014) Mitotic activation of the DISC1-inducible cyclic AMP phosphodiesterase-4D9 (PDE4D9), through multi-site phosphorylation, influences cell cycle progression. Cellular Signalling, 26(9), pp. 1958-1974. (doi: 10.1016/j.cellsig.2014.04.023)

2013

Brown, K.M. et al. (2013) Phosphodiesterase-8A binds to and regulates Raf-1 kinase. Proceedings of the National Academy of Sciences of the United States of America, 110(16), E1533-E1542. (doi: 10.1073/pnas.1303004110)

2011

Day, J. P. et al. (2011) Elucidation of a structural basis for the inhibitor-driven, p62 (SQSTM1)-dependent intracellular redistribution of cAMP phosphodiesterase-4A4 (PDE4A4). Journal of Medicinal Chemistry, 54(9), pp. 3331-3347. (doi: 10.1021/jm200070e)

2010

Kim, Hyun Wook, Ha, Sang Hoon, Lee, Mi Nam, Huston, Elaine ORCID logoORCID: https://orcid.org/0009-0001-6978-7134, Kim, Do-Hyung, Jang, Sung Key, Suh, Pann-Ghill, Houslay, Miles D. and Ryu, Sung Ho (2010) cAMP controls mTOR through regulation of the dynamic interaction between Rheb and Phosphodiesterase 4D. Molecular and Cellular Biology, 30(22), pp. 5406-5420. (doi: 10.1128/MCB.00217-10)

Kim, Hyun Wook, Ha, Sang Hoon, Lee, Mi Nam, Huston, Elaine ORCID logoORCID: https://orcid.org/0009-0001-6978-7134, Kim, Do-Hyung, Jang, Sung Key, Suh, Pann-Ghill., Houslay, Miles D. and Ryu, Sung H. (2010) Cyclic AMP Controls mTOR through Regulation of the Dynamic Interaction between Rheb and Phosphodiesterase 4D. Molecular and Cellular Biology, 30(22), pp. 5406-5420. (doi: 10.1128/MCB.00217-10)

Rampersad, Sarah N., Ovens, Jeffrey D., Huston, Elaine ORCID logoORCID: https://orcid.org/0009-0001-6978-7134, Umana, M. Bibiana, Wilson, Lindsay S., Netherton, Stuart J., Lynch, Martin J., Baillie, George S. ORCID logoORCID: https://orcid.org/0000-0003-2469-6316, Houslay, Miles D. and Maurice, Donald H. (2010) Cyclic AMP Phosphodiesterase 4D (PDE4D) Tethers EPAC1 in a Vascular Endothelial Cadherin (VE-Cad)-based Signaling Complex and Controls cAMP-mediated Vascular Permeability. Journal of Biological Chemistry, 285(44), pp. 33614-33622. (doi: 10.1074/jbc.M110.140004)

Zhu, H. et al. (2010) Evolutionarily Conserved Role of Calcineurin in Phosphodegron-Dependent Degradation of Phosphodiesterase 4D. Molecular and Cellular Biology, 30(18), pp. 4379-4390. (doi: 10.1128/MCB.01193-09)

2009

Meng, Dong, Lynch, Martin J., Huston, Elaine ORCID logoORCID: https://orcid.org/0009-0001-6978-7134, Beyermann, Michael, Eichhorst, Jenny, Adams, David R., Klusmann, Enno, Houslay, Miles D. and Baillie, George S. ORCID logoORCID: https://orcid.org/0000-0003-2469-6316 (2009) MEK1 binds directly to βArrestin1, influencing both its phosphorylation by ERK and the timing of its isoprenaline-stimulated internalization. Journal of Biological Chemistry, 284(17), pp. 11425-11435. (doi: 10.1074/jbc.M806395200) (PMID:19153083) (PMCID:PMC2670148)

2008

Huston, Elaine ORCID logoORCID: https://orcid.org/0009-0001-6978-7134, Lynch, Martin J., Mohamed, Ahmed, Collins, Daniel M., Hill, Elaine V., McLeod, Ruth, Krause, Eberhard, Baillie, George S. ORCID logoORCID: https://orcid.org/0000-0003-2469-6316 and Houslay, Miles D. (2008) EPAC and PKA allow cAMP dual control over DNA-PK nuclear translocation. Proceedings of the National Academy of Sciences of the United States of America, 105(35), pp. 12791-12796. (doi: 10.1073/pnas.0805167105)

McCahill, A., Huston, E. ORCID logoORCID: https://orcid.org/0009-0001-6978-7134, Li, X. and Houslay, M.D. (2008) PDE4 associates with different scaffolding proteins: modulating interactions as treatment for certain diseases. In: Klussman, E. and Scott, J. (eds.) Protein-Protein Interactions as New Drug Targets. Series: Handbook of Experimental Pharmacology (186). Springer: Berlin, Germany, pp. 125-166. ISBN 9783540728429 (doi: 10.1007/978-3-540-72843-6_6)

This list was generated on Fri Jun 20 03:29:56 2025 BST.
Jump to: Articles | Book Sections | Conference or Workshop Item
Number of items: 12.

Articles

Tanaka, M. et al. (2017) Aggregation of scaffolding protein DISC1 dysregulates phosphodiesterase 4 in Huntington’s disease. Journal of Clinical Investigation, 127(4), pp. 1438-1450. (doi: 10.1172/JCI85594) (PMID:28263187)

Sheppard, C. L. et al. (2014) Mitotic activation of the DISC1-inducible cyclic AMP phosphodiesterase-4D9 (PDE4D9), through multi-site phosphorylation, influences cell cycle progression. Cellular Signalling, 26(9), pp. 1958-1974. (doi: 10.1016/j.cellsig.2014.04.023)

Brown, K.M. et al. (2013) Phosphodiesterase-8A binds to and regulates Raf-1 kinase. Proceedings of the National Academy of Sciences of the United States of America, 110(16), E1533-E1542. (doi: 10.1073/pnas.1303004110)

Day, J. P. et al. (2011) Elucidation of a structural basis for the inhibitor-driven, p62 (SQSTM1)-dependent intracellular redistribution of cAMP phosphodiesterase-4A4 (PDE4A4). Journal of Medicinal Chemistry, 54(9), pp. 3331-3347. (doi: 10.1021/jm200070e)

Kim, Hyun Wook, Ha, Sang Hoon, Lee, Mi Nam, Huston, Elaine ORCID logoORCID: https://orcid.org/0009-0001-6978-7134, Kim, Do-Hyung, Jang, Sung Key, Suh, Pann-Ghill, Houslay, Miles D. and Ryu, Sung Ho (2010) cAMP controls mTOR through regulation of the dynamic interaction between Rheb and Phosphodiesterase 4D. Molecular and Cellular Biology, 30(22), pp. 5406-5420. (doi: 10.1128/MCB.00217-10)

Kim, Hyun Wook, Ha, Sang Hoon, Lee, Mi Nam, Huston, Elaine ORCID logoORCID: https://orcid.org/0009-0001-6978-7134, Kim, Do-Hyung, Jang, Sung Key, Suh, Pann-Ghill., Houslay, Miles D. and Ryu, Sung H. (2010) Cyclic AMP Controls mTOR through Regulation of the Dynamic Interaction between Rheb and Phosphodiesterase 4D. Molecular and Cellular Biology, 30(22), pp. 5406-5420. (doi: 10.1128/MCB.00217-10)

Rampersad, Sarah N., Ovens, Jeffrey D., Huston, Elaine ORCID logoORCID: https://orcid.org/0009-0001-6978-7134, Umana, M. Bibiana, Wilson, Lindsay S., Netherton, Stuart J., Lynch, Martin J., Baillie, George S. ORCID logoORCID: https://orcid.org/0000-0003-2469-6316, Houslay, Miles D. and Maurice, Donald H. (2010) Cyclic AMP Phosphodiesterase 4D (PDE4D) Tethers EPAC1 in a Vascular Endothelial Cadherin (VE-Cad)-based Signaling Complex and Controls cAMP-mediated Vascular Permeability. Journal of Biological Chemistry, 285(44), pp. 33614-33622. (doi: 10.1074/jbc.M110.140004)

Zhu, H. et al. (2010) Evolutionarily Conserved Role of Calcineurin in Phosphodegron-Dependent Degradation of Phosphodiesterase 4D. Molecular and Cellular Biology, 30(18), pp. 4379-4390. (doi: 10.1128/MCB.01193-09)

Meng, Dong, Lynch, Martin J., Huston, Elaine ORCID logoORCID: https://orcid.org/0009-0001-6978-7134, Beyermann, Michael, Eichhorst, Jenny, Adams, David R., Klusmann, Enno, Houslay, Miles D. and Baillie, George S. ORCID logoORCID: https://orcid.org/0000-0003-2469-6316 (2009) MEK1 binds directly to βArrestin1, influencing both its phosphorylation by ERK and the timing of its isoprenaline-stimulated internalization. Journal of Biological Chemistry, 284(17), pp. 11425-11435. (doi: 10.1074/jbc.M806395200) (PMID:19153083) (PMCID:PMC2670148)

Huston, Elaine ORCID logoORCID: https://orcid.org/0009-0001-6978-7134, Lynch, Martin J., Mohamed, Ahmed, Collins, Daniel M., Hill, Elaine V., McLeod, Ruth, Krause, Eberhard, Baillie, George S. ORCID logoORCID: https://orcid.org/0000-0003-2469-6316 and Houslay, Miles D. (2008) EPAC and PKA allow cAMP dual control over DNA-PK nuclear translocation. Proceedings of the National Academy of Sciences of the United States of America, 105(35), pp. 12791-12796. (doi: 10.1073/pnas.0805167105)

Book Sections

McCahill, A., Huston, E. ORCID logoORCID: https://orcid.org/0009-0001-6978-7134, Li, X. and Houslay, M.D. (2008) PDE4 associates with different scaffolding proteins: modulating interactions as treatment for certain diseases. In: Klussman, E. and Scott, J. (eds.) Protein-Protein Interactions as New Drug Targets. Series: Handbook of Experimental Pharmacology (186). Springer: Berlin, Germany, pp. 125-166. ISBN 9783540728429 (doi: 10.1007/978-3-540-72843-6_6)

Conference or Workshop Item

DeLeeuw, J., Weir, Jane, Copsey, Dickon, Roden, Chris, Deeley, Susan ORCID logoORCID: https://orcid.org/0000-0002-6712-3908, Huston, Elaine ORCID logoORCID: https://orcid.org/0009-0001-6978-7134, McVey, Mary ORCID logoORCID: https://orcid.org/0000-0003-3740-6023 and Finlay, Chris ORCID logoORCID: https://orcid.org/0000-0001-6079-1199 (2015) Developing Graduate Attributes and Improving Student Employability Through Work-based Learning: Opportunities, Successes and Challenges. 8th Annual University of Glasgow Learning and Teaching Conference, Glasgow, UK, 14 Apr 2015.

This list was generated on Fri Jun 20 03:29:56 2025 BST.