Dr Celestine Santosh
- Honorary Clinical Associate Professor (School of Psychology & Neuroscience)
email:
Celestine.Santosh@glasgow.ac.uk
West Glasgow Ambulatory Care Hospital, Dalnair Street, Yorkhill, Glasgow, G3 8SJ
Publications
2021
Learmonth, G. , Benwell, C. S.Y., Märker, G., Dascalu, D., Checketts, M. , Santosh, C., Barber, M., Walters, M. , Muir, K. W. and Harvey, M. (2021) Non-invasive brain stimulation in stroke patients (NIBS): a prospective randomized open blinded end-point (PROBE) feasibility trial using transcranial direct current stimulation (tDCS) in post-stroke hemispatial neglect. Neuropsychological Rehabilitation, 31(8), pp. 1163-1189. (doi: 10.1080/09602011.2020.1767161) (PMID:32498606)
Moreton, F. C., Cullen, B. , Dickie, D. A. , Lopez Gonzalez, R., Santosh, C., Delles, C. and Muir, K. W. (2021) Brain imaging factors associated with progression of subcortical hyperintensities in CADASIL over two year follow up. European Journal of Neurology, 28(1), pp. 220-228. (doi: 10.1111/ene.14534) (PMID:32931073)
2019
Deuchar, G. A., Van Kralingen, J. C., Work, L. M. , Santosh, C., Muir, K. W. , McCabe, C. and Macrae, I. M. (2019) Preclinical validation of the therapeutic potential of Glasgow Oxygen Level Dependent (GOLD) technology: A theranostic for acute stroke. Translational Stroke Research, 10(5), pp. 583-595. (doi: 10.1007/s12975-018-0679-y) (PMID:30506268)
2018
Moreton, F. C., Cullen, B. , Delles, C. , Santosh, C., Lopez Gonzalez, R., Dani, K. and Muir, K. W. (2018) Vasoreactivity in CADASIL: comparison to structural MRI and neuropsychology. Journal of Cerebral Blood Flow and Metabolism, 38(6), pp. 1085-1095. (doi: 10.1177/0271678X17710375) (PMID:28537106)
Deuchar, G. A., Brennan, D., Holmes, W. M. , Shaw, M., Macrae, I. M. and Santosh, C. (2018) Perfluorocarbon Enhanced Glasgow Oxygen Level Dependent (GOLD) magnetic resonance metabolic imaging identifies the penumbra following acute ischemic stroke. Theranostics, 8(6), pp. 1706-1722. (doi: 10.7150/thno.21685)
2017
Dani, K. A., Moreton, F. C., Santosh, C., Lopez, R., Brennan, D., Schwarzbauer, C., Goutcher, C., O’Hare, K., Macrae, I. M. and Muir, K. W. (2017) Oxygen challenge magnetic resonance imaging in healthy human volunteers. Journal of Cerebral Blood Flow and Metabolism, 37(1), pp. 366-376. (doi: 10.1177/0271678x15627827) (PMID:26787107) (PMCID:PMC5363753)
2016
Kalladka, D. et al. (2016) Human neural stem cells in patients with chronic ischaemic stroke (PISCES): a phase 1, first-in-man study. Lancet, 388(10046), pp. 787-796. (doi: 10.1016/S0140-6736(16)30513-X) (PMID:27497862)
Cullen, B. , Moreton, F. C., Stringer, M. S., Krishnadas, R. , Kalladka, D., López-González, M. R., Santosh, C., Schwarzbauer, C. and Muir, K. W. (2016) Resting state connectivity and cognitive performance in adults with cerebral autosomal-dominant arteriopathy with subcortical infarcts and leukoencephalopathy. Journal of Cerebral Blood Flow and Metabolism, 36(5), pp. 981-991. (doi: 10.1177/0271678X16636395) (PMID:26929239)
2015
Moreton, F., Santosh, C., McArthur, K. and Muir, K. (2015) Cerebral hyperperfusion on arterial spin labeling MRI during CADASIL migrainous encephalopathy. Neurology, 85(24), pp. 2177-2179. (doi: 10.1212/WNL.0000000000002214) (PMID:26567267)
2014
Robertson, C. A., McCabe, C. , Lopez-Gonzalez, M. R., Deuchar, G. A., Dani, K., Holmes, W. M. , Muir, K. W. , Santosh, C. and Macrae, I. M. (2014) Detection of ischemic penumbra using combined perfusion and T2* oxygen challenge imaging. International Journal of Stroke, 10(1), pp. 42-50. (doi: 10.1111/ijs.12327)
2012
Dani, K.A., Santosh, C., Brennan, D., Hadley, D.M. and Muir, K.W. (2012) Crossed cerebellar diaschisis: insights into oxygen challenge MRI. Journal of Cerebral Blood Flow and Metabolism, 32(12), pp. 2114-2117. (doi: 10.1038/jcbfm.2012.142)
Holmes, W.M. , Lopez-Gonzalez, M.R., Gallagher, L., Deuchar, G., Macrae, I. and Santosh, C. (2012) Novel MRI detection of the ischemic penumbra: direct assessment of metabolic integrity. NMR in Biomedicine, 25(2), pp. 295-304. (doi: 10.1002/nbm.1748)
2011
Baskerville, T., Deuchar, G. A., McCabe, C. , Robertson, C. A., Holmes, W. M. , Santosh, C. and Macrae, I. M. (2011) Influence of 100% and 40% oxygen on penumbral blood flow, oxygen level, and T2*-weighted MRI in a rat stroke model. Journal of Cerebral Blood Flow and Metabolism, 31(8), pp. 1799-1806. (doi: 10.1038/jcbfm.2011.65)
Robertson, C. A., McCabe, C. , Gallagher, L., Lopez Gonzalez, M. d., Holmes, W. M. , Condon, B., Muir, K. W. , Santosh, C. and Macrae, I. M. (2011) Stroke penumbra defined by an MRI-based oxygen challenge technique: 2. Validation based on the consequences of reperfusion. Journal of Cerebral Blood Flow and Metabolism, 31(8), pp. 1788-1798. (doi: 10.1038/jcbfm.2011.67)
Robertson, C. A., McCabe, C. , Gallagher, L., Lopez-Gonzalez, M. d., Holmes, W. M. , Condon, B., Muir, K. W. , Santosh, C. and Macrae, I. M. (2011) Stroke penumbra defined by an MRI-based oxygen challenge technique: 1. validation using [14C]2-deoxyglucose autoradiography. Journal of Cerebral Blood Flow and Metabolism, 31, pp. 1778-1787. (doi: 10.1038/jcbfm.2011.66)
2010
Dani, K. A., Santosh, C., Brennan, D., McCabe, C. , Holmes, W. M. , Condon, B., Hadley, D. M., Macrae, I. M., Shaw, M. and Muir, K. W. (2010) T2*-weighted magnetic resonance imaging with hyperoxia in acute ischemic stroke. Annals of Neurology, 68(1), pp. 37-47. (doi: 10.1002/ana.22032)
Awadh, M., MacDougall, N., Santosh, C., Teasdale, E., Baird, T. and Muir, K.W. (2010) Early recurrent ischemic stroke complicating intravenous thrombolysis for stroke: incidence and association with atrial fibrillation. Stroke, 41(9), pp. 1990-1995. (doi: 10.1161/STROKEAHA.109.569459)
2008
Santosh, C. et al. (2008) Potential use of oxygen as a metabolic biosensor in combination with T2*-weighted MRI to define the ischemic penumbra. Journal of Cerebral Blood Flow and Metabolism, 28(10), pp. 1742-1753. (doi: 10.1038/jcbfm.2008.56)
2004
Abdallah, J. et al. (2004) Measurement of the W-pair production cross-section and W branching ratios in e+ e - collisions at root s=161-209 GeV. European Physical Journal C, 34(2), pp. 127-144. (doi: 10.1140/epjc/s2004-01709-5)
Articles
Learmonth, G. , Benwell, C. S.Y., Märker, G., Dascalu, D., Checketts, M. , Santosh, C., Barber, M., Walters, M. , Muir, K. W. and Harvey, M. (2021) Non-invasive brain stimulation in stroke patients (NIBS): a prospective randomized open blinded end-point (PROBE) feasibility trial using transcranial direct current stimulation (tDCS) in post-stroke hemispatial neglect. Neuropsychological Rehabilitation, 31(8), pp. 1163-1189. (doi: 10.1080/09602011.2020.1767161) (PMID:32498606)
Moreton, F. C., Cullen, B. , Dickie, D. A. , Lopez Gonzalez, R., Santosh, C., Delles, C. and Muir, K. W. (2021) Brain imaging factors associated with progression of subcortical hyperintensities in CADASIL over two year follow up. European Journal of Neurology, 28(1), pp. 220-228. (doi: 10.1111/ene.14534) (PMID:32931073)
Deuchar, G. A., Van Kralingen, J. C., Work, L. M. , Santosh, C., Muir, K. W. , McCabe, C. and Macrae, I. M. (2019) Preclinical validation of the therapeutic potential of Glasgow Oxygen Level Dependent (GOLD) technology: A theranostic for acute stroke. Translational Stroke Research, 10(5), pp. 583-595. (doi: 10.1007/s12975-018-0679-y) (PMID:30506268)
Moreton, F. C., Cullen, B. , Delles, C. , Santosh, C., Lopez Gonzalez, R., Dani, K. and Muir, K. W. (2018) Vasoreactivity in CADASIL: comparison to structural MRI and neuropsychology. Journal of Cerebral Blood Flow and Metabolism, 38(6), pp. 1085-1095. (doi: 10.1177/0271678X17710375) (PMID:28537106)
Deuchar, G. A., Brennan, D., Holmes, W. M. , Shaw, M., Macrae, I. M. and Santosh, C. (2018) Perfluorocarbon Enhanced Glasgow Oxygen Level Dependent (GOLD) magnetic resonance metabolic imaging identifies the penumbra following acute ischemic stroke. Theranostics, 8(6), pp. 1706-1722. (doi: 10.7150/thno.21685)
Dani, K. A., Moreton, F. C., Santosh, C., Lopez, R., Brennan, D., Schwarzbauer, C., Goutcher, C., O’Hare, K., Macrae, I. M. and Muir, K. W. (2017) Oxygen challenge magnetic resonance imaging in healthy human volunteers. Journal of Cerebral Blood Flow and Metabolism, 37(1), pp. 366-376. (doi: 10.1177/0271678x15627827) (PMID:26787107) (PMCID:PMC5363753)
Kalladka, D. et al. (2016) Human neural stem cells in patients with chronic ischaemic stroke (PISCES): a phase 1, first-in-man study. Lancet, 388(10046), pp. 787-796. (doi: 10.1016/S0140-6736(16)30513-X) (PMID:27497862)
Cullen, B. , Moreton, F. C., Stringer, M. S., Krishnadas, R. , Kalladka, D., López-González, M. R., Santosh, C., Schwarzbauer, C. and Muir, K. W. (2016) Resting state connectivity and cognitive performance in adults with cerebral autosomal-dominant arteriopathy with subcortical infarcts and leukoencephalopathy. Journal of Cerebral Blood Flow and Metabolism, 36(5), pp. 981-991. (doi: 10.1177/0271678X16636395) (PMID:26929239)
Moreton, F., Santosh, C., McArthur, K. and Muir, K. (2015) Cerebral hyperperfusion on arterial spin labeling MRI during CADASIL migrainous encephalopathy. Neurology, 85(24), pp. 2177-2179. (doi: 10.1212/WNL.0000000000002214) (PMID:26567267)
Robertson, C. A., McCabe, C. , Lopez-Gonzalez, M. R., Deuchar, G. A., Dani, K., Holmes, W. M. , Muir, K. W. , Santosh, C. and Macrae, I. M. (2014) Detection of ischemic penumbra using combined perfusion and T2* oxygen challenge imaging. International Journal of Stroke, 10(1), pp. 42-50. (doi: 10.1111/ijs.12327)
Dani, K.A., Santosh, C., Brennan, D., Hadley, D.M. and Muir, K.W. (2012) Crossed cerebellar diaschisis: insights into oxygen challenge MRI. Journal of Cerebral Blood Flow and Metabolism, 32(12), pp. 2114-2117. (doi: 10.1038/jcbfm.2012.142)
Holmes, W.M. , Lopez-Gonzalez, M.R., Gallagher, L., Deuchar, G., Macrae, I. and Santosh, C. (2012) Novel MRI detection of the ischemic penumbra: direct assessment of metabolic integrity. NMR in Biomedicine, 25(2), pp. 295-304. (doi: 10.1002/nbm.1748)
Baskerville, T., Deuchar, G. A., McCabe, C. , Robertson, C. A., Holmes, W. M. , Santosh, C. and Macrae, I. M. (2011) Influence of 100% and 40% oxygen on penumbral blood flow, oxygen level, and T2*-weighted MRI in a rat stroke model. Journal of Cerebral Blood Flow and Metabolism, 31(8), pp. 1799-1806. (doi: 10.1038/jcbfm.2011.65)
Robertson, C. A., McCabe, C. , Gallagher, L., Lopez Gonzalez, M. d., Holmes, W. M. , Condon, B., Muir, K. W. , Santosh, C. and Macrae, I. M. (2011) Stroke penumbra defined by an MRI-based oxygen challenge technique: 2. Validation based on the consequences of reperfusion. Journal of Cerebral Blood Flow and Metabolism, 31(8), pp. 1788-1798. (doi: 10.1038/jcbfm.2011.67)
Robertson, C. A., McCabe, C. , Gallagher, L., Lopez-Gonzalez, M. d., Holmes, W. M. , Condon, B., Muir, K. W. , Santosh, C. and Macrae, I. M. (2011) Stroke penumbra defined by an MRI-based oxygen challenge technique: 1. validation using [14C]2-deoxyglucose autoradiography. Journal of Cerebral Blood Flow and Metabolism, 31, pp. 1778-1787. (doi: 10.1038/jcbfm.2011.66)
Dani, K. A., Santosh, C., Brennan, D., McCabe, C. , Holmes, W. M. , Condon, B., Hadley, D. M., Macrae, I. M., Shaw, M. and Muir, K. W. (2010) T2*-weighted magnetic resonance imaging with hyperoxia in acute ischemic stroke. Annals of Neurology, 68(1), pp. 37-47. (doi: 10.1002/ana.22032)
Awadh, M., MacDougall, N., Santosh, C., Teasdale, E., Baird, T. and Muir, K.W. (2010) Early recurrent ischemic stroke complicating intravenous thrombolysis for stroke: incidence and association with atrial fibrillation. Stroke, 41(9), pp. 1990-1995. (doi: 10.1161/STROKEAHA.109.569459)
Santosh, C. et al. (2008) Potential use of oxygen as a metabolic biosensor in combination with T2*-weighted MRI to define the ischemic penumbra. Journal of Cerebral Blood Flow and Metabolism, 28(10), pp. 1742-1753. (doi: 10.1038/jcbfm.2008.56)
Abdallah, J. et al. (2004) Measurement of the W-pair production cross-section and W branching ratios in e+ e - collisions at root s=161-209 GeV. European Physical Journal C, 34(2), pp. 127-144. (doi: 10.1140/epjc/s2004-01709-5)