- Research Associate (Immunology)
III - GBRC
Glasgow G12 8TA
Research in my lab is focussed on understanding the underlying differences between naïve and memory CD4 T cells. CD4 T cells are the orchestrators of the immune system, directing and controlling many other immune cell types. Memory CD4 T cells develop following an adaptive immune response and can act more quickly and effectively to direct a secondary immune attack. However, these superior immune responses require tight regulation of memory CD4 T cell activity. In autoimmune diseases such as rheumatoid arthritis, memory or activated CD4 T cells are thought to coordinate the inappropriate cellular infiltration into joints that causes bone damage and chronic pain.
The major goal of our research is to understand the cellular and molecular differences that enable memory CD4 T cells to respond differently from their naïve counterparts. Thus, we will be able to open new avenues to improve their responses in vaccination and inhibit them in autoimmune diseases.