Professor Massimo Palmarini

  • Director of Centre for Virus Research (Centre for Virus Research)
  • Associate Academic (School of Veterinary Medicine)

telephone: 01413302356
email: Massimo.Palmarini@glasgow.ac.uk

Research interests

CVR logo

Our laboratory studies the biology and pathogenesis of livestock diseases induced by emerging arboviruses such as Bluetongue virus (BTV) and Schmallenberg virus (SBV). Approximately 30 percent of all infectious diseases that emerged between 1990 and 2000 were caused by arthropod-borne viruses (arbovirus). This is probably the result of a combination of factors including a dramatic increase in travelling and commercial exchanges, climate and ecological changes and increased livestock production. In addition, changes in trading and commercial policies have created optimal conditions for the movement of infected vertebrate hosts and invertebrate vectors over wide geographical areas.

Research in our laboratory is funded by various sources including the Wellcome Trust, BBSRC and EU.

Grants

Grants and Awards listed are those received whilst working with the University of Glasgow.

  • US-UK BBSRC-NIFA Collab: Control of emerging bunyaviruses
    Biotechnology and Biological Sciences Research Council
    2015 - 2018
     
  • The Centre for Virus Research
    Wellcome Trust
    2015 - 2020
     
  • Transmission dynamics of African swine fever in an endemic setting at the livestock-wildlife interface
    Wellcome Trust
    2015 - 2020
     
  • Development of Synthetic Vaccines for African Horse Sickness
    Horserace Betting Levy Board
    2014 - 2017
     
  • Capital Prioritisation Panel February 2014
    Medical Research Council
    2014 - 2015
     
  • Capital Equipment Award
    Medical Research Council
    2013 - 2015
     
  • Centre for Virus Research
    Medical Research Council
    2013 - 2016
     
  • Medical Research Foundation Equipment Grant in Memory of Mr Alfred Tartellin
    Medical Research Council
    2013 - 2013
     
  • Capital Equipment Award
    Medical Research Council
    2013 - 2014
     
  • Centenary Funding
    Medical Research Council
    2012 - 2013
     
  • Centenary Public Funding
    Medical Research Council
    2012 - 2013
     
  • Phylogeography, transmission dynamics and pathogenesis of bluetongue
    Wellcome Trust
    2011 - 2016
     
  • Intra and inter-host evolution of equine and swine influenza viruses
    Wellcome Trust
    2011 - 2012
     
  • Endogenous retroviruses and placental morphogenesis
    National Institute of Allergy and Infectious Diseases
    2011 - 2013
     
  • Phylogeography, transmission dynamics and pathogenesis of bluetongue
    Wellcome Trust
    2011 - 2016
     
  • Molecular and reverse genetics studies of orbivirus transmission, host responses, epidemiology and diagnostic systems
    BBSRC
    2011 - 2014
     
  • Improving existing vaccine platforms to minimise the economic impact of emerging Bluetongue virus (BTV) serotypes
    BBSRC
    2011 - 2014
     
  • Development of experimental tools to investigate the innate immune response to bluetongue virus
    Wellcome Trust
    2010 - 2011
     
  • Centre for Integrated Virology
    MRC
    2010 - 2015
     
  • Molecular pathogenesis of ovine pulmonary adenocarcinoma - host genetics and age as determinants of disease progression
    BBSRC
    2008 - 2011
     
  • Development of Novel Technologies to Fight Viral Diseases in Farm Animals: A Scottish Network of Excellence.
    Scottish Funding Council
    2007 - 2012
     
  • Mechanisms of retrovirus-induced cell transformation in a naturally occurring lung cancer of sheep
    Wellcome Trust
    2007 - 2011
     
  • A novel mechanism of retroviral interference
    Wellcome Trust
    2005 - 2011
     
  • Oncogenesis in retrovirus-induced lung cancer
    National Institute of Health
    2005 - 2006
     
  • Royal Society Wolfson Research Merit Award
    Royal Society
    2004 - 2009
     
  • Pathogenesis of ovine pulmonary adeno carcinoma: Mechanism of cellular transformation in vivo and susceptibility to disease
    Italian Ministry of Health
    2004 - 2007
     

Additional information

Editorial Board

  • 2010 - 2012: Journal of Virology

Grant Advisory Board

  • 2011 - 2014: Research Excellence Framework (REF) - Sub-Panel 6 (Agriculture, Veterinary and Food Science)
  • 2010 - 2010: MRC - Iinfection and Immunity Board Scientific Quinquennial Review of the National Institute for Medical Research (NIMR) Infection Group
  • 2010 - ongoing: Wellcome Trust - Steering Group of the Clinical Veterinary Research Training Initiative
  • 2009 - 2012: Royal Society of Edinburgh - Clinical Sciences Sectional Committee
  • 2009 - 2009: Kyoto University, Japan - Chair of the Institute for Virus Research Site Visit Review Panel
  • 2008 - 2009: European Medicines Agency - Animal Retroviruses Advisory Board
  • 2007 - 2007: DEFRA - Veterinary Laboratory Agency Audit Team
  • 2006 - 2009: BBSRC - Ad hoc member Animal Committee A
  • 2006 - 2009: Wellcome Trust - Immunology and Infectious Disease Funding Committee
  • 2005 - 2007: Royal College of Veterinary Surgeons - Research Committee

Invited International Presentations

  • 2011: Baltimore, USA - National Foundation for Infectious Diseases, 14th Annual Conference on Vaccine Research
  • 2011: Uppsala, Sweden - European Society of Veterinay Pathology 29th Annual Meeting
  • 2011: Minneapolis, USA - American Society for Virology 30th Annual Meeting
  • 2010: London, UK - European Science Foundation Exploratory Workshop, Archaelogy of Sheep Domestication: New Approaches
  • 2010: Como, Italy - 4th European Congress of Virology
  • 2010: Castel Sardo, Italy - 7th Meeting of the Italian Society of Veterinary Pathologists
  • 2009: Graves Mountain Lodge, USA - Workshop on Host Restriction of Viral Infection
  • 2008: Salzburg, Austria - Symposium on Natural Genetic Engineering and Natural Genome Editing
  • 2007: Edinburgh, UK - European Science Foundation Workshop, Genetic Models of Disease Resistance in Transgenic Livestock
  • 2006: Mystic, USA - Workshop on 'Endogenous Retroviruses and Retroelements'

Prizes, Awards and Distinctions

  • 2004: Wolfson-Royal Society - Research Merit Award
  • 2003: University of Georgia - John M. Bowen Award for Excellence in Animal Research
  • 2002: University of Georgia- Pfizer - Pfizer Award for Research Excellence

Professional Learned Society

  • 2010 - ongoing: Society of Biology - Elected Fellow
  • 2008 - ongoing: Royal Society of Edinburgh - Elected Fellow

Research Fellowship

  • 2001 - 2006: Distinguished Cancer Research Scientist - Georgia Cancer Coalition
  • 1999 - 2000: American Cancer Society - (California Division) Post-Doctoral Fellowship
  • 1997 - 1999: Wellcome Trust International Prize Travelling Fellowship
  • 1994 - 1996: EU Marie Curie Fellow

Publications

List by: Type | Date

Jump to: 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006 | 2005 | 2004 | 2003 | 2002 | 2001 | 2000 | 1999 | 1998 | 1996 | 1995 | 1994 | 1993
Number of items: 95.

2016

Ratinier, M., Shaw, A. E., Barry, G., Gu, Q., Di Gialleonardo, L., Janowicz, A., Varela, M., Randall, R. E., Caporale, M., and Palmarini, M. (2016) Bluetongue virus NS4 protein is an interferon antagonist and a determinant of virus virulence. Journal of Virology, (doi:10.1128/JVI.00422-16) (PMID:27009961) (Early Online Publication)

Varela, M. et al. (2016) Mutations in the Schmallenberg virus Gc glycoprotein facilitate cellular protein synthesis shutoff and restore pathogenicity of NSs deletion mutants in mice. Journal of Virology, (doi:10.1128/JVI.00424-16) (PMID:26984728) (Early Online Publication)

2015

Stewart, M. et al. (2015) Characterisation of a second open reading frame in genome segment 10 of bluetongue virus. Journal of General Virology, 96(11), pp. 3280-3293. (doi:10.1099/jgv.0.000267) (PMID:26290332)

Ftaich, N. et al. (2015) Turnover rate of NS3 proteins modulates bluetongue virus replication kinetics in a host-specific manner. Journal of Virology, 89(20), pp. 10467-10481. (doi:10.1128/jvi.01541-15) (PMID:26246581)

Nomikou, K., Hughes, J., Wash, R., Kellam, P., Breard, E., Zientara, S., Palmarini, M., Biek, R., and Mertens, P. (2015) Widespread reassortment shapes the evolution and epidemiology of bluetongue virus following European invasion. PLoS Pathogens, 11(8), e1005056. (doi:10.1371/journal.ppat.1005056) (PMID:26252219) (PMCID:PMC4529188)

Janowicz, A., Caporale, M., Shaw, A., Gulletta, S., Di Gialleonardo, L., Ratinier, M., and Palmarini, M. (2015) Multiple genome segments determine virulence of bluetongue virus serotype 8. Journal of Virology, 89(10), pp. 5238-5249. (doi:10.1128/JVI.00395-15) (PMID:25822026) (PMCID:PMC4442542)

Murphy, L. et al. (2015) The sheep tetherin paralog oBST2B blocks envelope glycoprotein incorporation into nascent retroviral virions. Journal of Virology, 89(1), pp. 535-544. (doi:10.1128/JVI.02751-14)

Blomström, A.-L. et al. (2015) Transcriptome analysis reveals the host response to Schmallenberg virus in bovine cells and antagonistic effects of the NSs protein. BMC Genomics, 16, 324. (doi:10.1186/s12864-015-1538-9) (PMID:25896169) (PMCID:PMC4404599)

Brennan, B. et al. (2015) In memoriam – Richard M. Elliott (1954–2015). Journal of General Virology, 96(8), pp. 1975-1978. (doi:10.1099/jgv.0.000241) (PMID:26315040)

2014

Nunes, S. F., Hamers, C., Ratinier, M., Shaw, A., Brunet, S., Hudelet, P., and Palmarini, M. (2014) A synthetic biology approach for a vaccine platform against known and newly emerging serotypes of bluetongue virus. Journal of General Virology, 29(7), pp. 912-920. (doi:10.1128/JVI.02183-14) (PMID:25142610) (PMCID:PMC4248921)

Caporale, M., Di Gialleonorado, L., Janowicz, A., Wilkie, G., Shaw, A., Savini, G., Van Rijn, P. A., Mertens, P., Di Ventura, M., and Palmarini, M. (2014) Virus and host factors affecting the clinical outcome of bluetongue virus infection. Journal of Virology, 88(18), pp. 10399-10411. (doi:10.1128/JVI.01641-14)

Barry, G. et al. (2014) NSs protein of Schmallenberg virus counteracts the antiviral response of the cell by inhibiting its transcriptional machinery. Journal of General Virology, 95(Pt. 8), pp. 1640-1646. (doi:10.1099/vir.0.065425-0)

Seehusen, F. et al. (2014) Skeletal muscle hypoplasia represents the only significant lesion in peripheral organs of ruminants infected with schmallenberg virus during gestation. Journal of Comparative Pathology, 151(2-3), pp. 148-152. (doi:10.1016/j.jcpa.2014.04.006)

Palmarini, M. (2014) Bluetongue: A rich history filled with many landmarks in virology……and more to be uncovered! Virus Research, 182, pp. 3-4. (doi:10.1016/j.virusres.2014.02.015)

Gerhauser, I., Weigand, M., Hahn, K., Herder, V., Wohlsein, P., Habierski, A., Varela, M., Palmarini, M., and Baumgärtner, W. (2014) Lack of Schmallenberg virus in ruminant brain tissues archived from 1961 to 2010 in Germany. Journal of Comparative Pathology, 150(2-3), pp. 151-154. (doi:10.1016/j.jcpa.2013.11.210)

Armezzani, A., Varela, M., Spencer, T., Palmarini, M., and Arnaud, F. (2014) "Ménage à Trois": the evolutionary interplay between JSRV, enJSRVs and domestic sheep. Viruses, 6(12), pp. 4926-4945. (doi:10.3390/v6124926)

2013

Caporale, M. et al. (2013) Host species barriers to jaagsiekte sheep retrovirus replication and carcinogenesis. Journal of Virology, 87(19), pp. 10752-10762. (doi:10.1128/JVI.01472-13)

Schnettler, E., Ratinier, M., Watson, M., Shaw, A. E., McFarlane, M., Varela, M., Elliott, R. M., Palmarini, M., and Kohl, A. (2013) RNA interference targets arbovirus replication in Culicoides cells. Journal of Virology, 87(5), pp. 2441-2454. (doi:10.1128/JVI.02848-12) (PMID:23269795) (PMCID:PMC3571378)

Shaw, A.E. et al. (2013) Reassortment between two serologically unrelated bluetongue virus strains is flexible and can involve any genome segment. Journal of Virology, 87(1), pp. 543-557. (doi:10.1128/JVI.02266-12)

Herder, V., Hansmann, F., Wohlsein, P., Peters, M., Varela, M., Palmarini, M., and Baumgärtner, W. (2013) Immunophenotyping of inflammatory cells associated with schmallenberg virus infection of the central nervous system of ruminants. PLoS ONE, 8(5), e62939. (doi:10.1371/journal.pone.0062939)

Martineau, H.M., Dagleish, M.P., Cousens, C., Underwood, C., Forbes, V., Palmarini, M., and Griffiths, D.I. (2013) Cellular differentiation and proliferation in the ovine lung during gestation and early postnatal development. Journal of Comparative Pathology, 149(2-3), pp. 255-267. (doi:10.1016/j.jcpa.2012.11.239)

Rasmussen, L., Savini, G., Lorusso, A., Bellacicco, A., Palmarini, M., Caporale, M., Rasmussen, T., Belsham, G.J., and Bøtner, A. (2013) Transplacental transmission of field and rescued strains of BTV-2 and BTV-8 in experimentally infected sheep. Veterinary Research, 44(75), (doi:10.1186/1297-9716-44-75)

Shaw, A.E., Mellor, D.J., Purse, B.V., Shaw, P.E., McCorkell, B.F., and Palmarini, M. (2013) Transmission of Schmallenberg virus in a housed dairy herd in the UK. Veterinary Record, 173(24), p. 609. (doi:10.1136/vr.101983)

Varela, M. et al. (2013) Schmallenberg virus pathogenesis, tropism and interaction with the innate immune system of the host. PLoS Pathogens, 9(1), e1003133. (doi:10.1371/journal.ppat.1003133) (PMID:23326235) (PMCID:PMC3542112)

2012

Shaw, A.E. et al. (2012) Drosophila melanogaster as a model organism for bluetongue virus replication and tropism. Journal of Virology, 86(17), pp. 9015-9024. (doi:10.1128/JVI.00131-12) (PMID:22674991) (PMCID:PMC3416142)

Spencer, T.E., and Palmarini, M. (2012) Application of next generation sequencing in mammalian embryogenomics: lessons learned from endogenous betaretroviruses of sheep. Animal Reproduction Science, 134(1-2), pp. 95-103. (doi:10.1016/j.anireprosci.2012.08.016)

Armezzani, A., Murphy, L., Spencer, T. E., Palmarini, M., and Arnaud, F. (2012) The evolutionary interplay between exogenous and endogenous sheep betaretroviruses. In: Witzany, G. (ed.) Viruses: Essential Agents of Life. Springer Netherlands: Dordrecht, pp. 293-307. ISBN 9789400748989 (doi:10.1007/978-94-007-4899-6_15)

Spencer, T.E., and Palmarini, M. (2012) Endogenous retroviruses of sheep: a model system for understanding physiological adaptation to an evolving ruminant genome. Journal of Reproduction and Development, 58(1), pp. 33-37. (doi:10.1262/jrd.2011-026)

2011

Caporale, M. et al. (2011) Determinants of bluetongue virus virulence in murine models of disease. Journal of Virology, 85(21), pp. 11479-11489. (doi:10.1128/JVI.05226-11)

Armezzani, A., Arnaud, F., Caporale, M., di Meo, G., Iannuzzi, L., Murgia, C., and Palmarini, M. (2011) The Signal Peptide of a Recently Integrated Endogenous Sheep Betaretrovirus Envelope Plays a Major Role in Eluding Gag-Mediated Late Restriction. Journal of Virology, 85(14), pp. 7118-7128. (doi:10.1128/JVI.00407-11)

Murgia, C., Ceesay, O., Caporale, M., Di Francesco, G., Ferri, N., Varasano, V., de las Heras, M., and Palmarini, M. (2011) Lung adenocarcinoma originates from retrovirus infection of proliferating type 2 pneumocytes during pulmonary post-natal development or tissue repair. PLoS Pathogens, 7(3), e1002014. (doi:10.1371/journal.ppat.1002014)

Ratinier, M. et al. (2011) Identification and characterization of a novel non-structural protein of bluetongue virus. PLoS Pathogens, 7(12), e1002477. (doi:10.1371/journal.ppat.1002477) (PMID:22241985) (PMCID:PMC3248566)

2010

Black, S.G. et al. (2010) Viral particles of endogenous betaretroviruses are released in the sheep uterus and infect the conceptus trophectoderm in a transspecies embryo transfer model. Journal of Virology, 84(18), pp. 9078-9085. (doi:10.1128/JVI.00950-10)

Arnaud, F., Black, S.G., Murphy, L., Griffiths, D.J., Neil, S.J., Spencer, T.E., and Palmarini, M. (2010) Interplay between ovine bone marrow stromal cell antigen 2/tetherin and endogenous retroviruses. Journal of Virology, 84(9), pp. 4415-4425. (doi:10.1128/JVI.00029-10)

Black, S.G., Arnaud, F., Palmarini, M., and Spencer, T.E. (2010) Endogenous Retroviruses in Trophoblast Differentiation and Placental Development. American Journal of Reproductive Immunology, 64(4), pp. 255-264. (doi:10.1111/j.1600-0897.2010.00860.x)

Dudley, J. P., Mertz, J. A., Bhadra, S., Palmarini, M., and Kozak, C. A. (2010) Endogenous retroviruses and cancer. In: Retroviruses and Insights into Cancer. Springer New York: New York, NY, pp. 119-162. ISBN 9780387095806 (doi:10.1007/978-0-387-09581-3_5)

Miyazawa, T., Yoshikawa, R., Golder, M., Okada, M., Stewart, H., and Palmarini, M. (2010) Isolation of an Infectious Endogenous Retrovirus in a Proportion of Live Attenuated Vaccines for Pets. Journal of Virology, 84(7), pp. 3690-3694. (doi:10.1128/JVI.02715-09)

Spencer, T.E., Black, S.G., Arnaud, F., and Palmarini, M. (2010) Endogenous retroviruses of sheep: a model system for understanding physiological adaptation to an evolving ruminant genome. Society of Reproduction and Fertility Supplement, 67, pp. 95-104.

Varela, M., and Palmarini, M. (2010) Multitasking: Making the Most out of the Retroviral Envelope. Viruses, 2(8), pp. 1571-1576. (doi:10.3390/v2081571)

2009

Chessa, B. et al. (2009) Revealing the history of sheep domestication using retrovirus integrations. Science, 324(5926), pp. 532-536. (doi:10.1126/science.1170587)

Caporale, M., Arnaud, F., Mura, M., Golder, M., Murgia, C., and Palmarini, M. (2009) The Signal Peptide of a Simple Retrovirus Envelope Functions as a Posttranscriptional Regulator of Viral Gene Expression. Journal of Virology, 83(9), pp. 4591-4604. (doi:10.1128/JVI.01833-08)

Heslin, D.J., Murcia, P., Arnaud, F., Van Doorslaer, K., Palmarini, M., and Lenz, J. (2009) A single amino acid substitution in a segment of the CA protein within gag that has similarity to human immunodeficiency virus type 1 blocks infectivity of a human endogenous retrovirus K provirus in the human genome. Journal of Virology, 83(2), (doi:10.1128/JVI.01439-08)

Mortuza, G.B., Goldstone, D.C., Pashley, C., Haire, L.F., Palmarini, M., Taylor, W.R., Stoye, J.P., and Taylor, I.A. (2009) Structure of the capsid amino-terminal domain from the betaretrovirus, jaagsiekte sheep retrovirus. Journal of Molecular Biology, 386(4), pp. 1179-1192. (doi:10.1016/j.jmb.2008.10.066)

Murcia, P., Donachie, W., and Palmarini, M. (2009) Viral pathogens of domestic animals and their impact on biology, medicine and agriculture. In: Schaechter, M. (ed.) Encyclopedia of Microbiology, Third Edition. Elsevier Inc., pp. 805-819. ISBN 9780123739445 (doi:10.1016/B978-012373944-5.00368-0)

Varela, M., Spencer, T.E., Palmarini, M., and Arnaud, F. (2009) Friendly viruses the special relationship between endogenous retroviruses and their host. In: Witzany, G. (ed.) Natural Genetic Engineering and Natural Genome Editing. Series: Annals of the New York Academy of Sciences (1178). New York Academy of Sciences, pp. 157-172. ISBN 9781573317658 (doi:10.1111/j.1749-6632.2009.05002.x)

2008

Arnaud, F., Varela, M., Spencer, T.E., and Palmarini, M. (2008) Coevolution of endogenous Betaretroviruses of sheep and their host. Cellular and Molecular Life Sciences, 65(21), pp. 3422-3432. (doi:10.1007/s00018-008-8500-9)

Palmarini, M. (2008) A large animal model to evaluate the effects of Hsp90 inhibitors for the treatment of lung adenocarcinoma. Virology, 371(1), pp. 206-215. (doi:10.1016/j.virol.2007.09.041)

Sharp, J.M., de las Heras, M., Spencer, T.E., and Palmarini, M. (2008) Jaagsiekte sheep retrovirus. In: Mahy, B. and van Regenmortel, M. (eds.) Encyclopedia of Virology, Third Edition. Elsevier Ltd.: Oxford, pp. 175-182. ISBN 9780123744104 (doi:10.1016/B978-012374410-4.00675-0)

2007

De Las Heras Guillamon, M., Murcia, P., Ortín, A., Azúa, J., Borderías, L., Álvarez, R., Jiménez-Más, J. A., Marchetti, A., and Palmarini, M. (2007) Jaagsiekte sheep retrovirus is not detected in human lung adenocarcinomas expressing antigens related to the Gag polyprotein of betaretrovirus. Cancer Letters, 258(1), pp. 22-30. (doi:10.1016/j.canlet.2007.08.006) (PMID:17889995)

Arnaud, F. et al. (2007) A paradigm for virus-host coevolution: sequential counter-adaptations between endogenous and exogenous retroviruses. PLoS Pathogens, 3(11), e170. (doi:10.1371/journal.ppat.0030170)

Arnaud, F., Murcia, P.R., and Palmarini, M. (2007) Mechanisms of late restriction induced by an endogenous retrovirus. Journal of Virology, 81(20), pp. 11441-11451. (doi:10.1128/JVI.01214-07)

Cousens, C., Maeda, N., Murgia, C., Dagleish, M., Palmarini, M., and Fan, H. (2007) In vivo tumorigenesis by Jaagsiekte sheep retrovirus (JSRV) requires Y590 in Env TM, but not full-length orfX open reading frame. Virology, 367, pp. 413-421. (doi:10.1016/j.virol.2007.06.004)

Murcia, P.R., Arnaud, F., and Palmarini, M. (2007) The transdominant endogenous retrovirus enJS56A1 associates with and blocks intracellular trafficking of Jaagsiekte sheep retrovirus Gag. Journal of Virology, 81(4), pp. 1762-1772. (doi:10.1128/JVI.01859-06)

Nolan, A., and Palmarini, M. (2007) Requirements for veterinary research and the recruitment of veterinary surgeons into research. Veterinary Record, 161(11), pp. 368-370. (doi:10.1136/vr.161.11.368)

Palmarini, M. (2007) A veterinary twist on pathogen biology. PLoS Pathogens, 3(2), e12. (doi:10.1371/journal.ppat.0030012)

Spencer, T., Johnson, G., Bazer, F., Burghardt, R., and Palmarini, M. (2007) Pregnancy recognition and conceptus implantation in domestic ruminants: Roles of progesterone, interferons and endogenous retroviruses. Reproduction Fertility and Development, 19, pp. 65-78. (doi:10.1071/RD06102)

2006

Caporale, M., Cousens, C., Centorame, P., Pinoni, C., De Las Heras Guillamon, M., and Palmarini, M. (2006) Expression of the Jaagsiekte sheep retrovirus envelope glycoprotein is sufficient to induce lung tumors in sheep. Journal of Virology, 80(16), pp. 8030-8037. (doi:10.1128/JVI.00474-06)

Dunlap, K., Palmarini, M., Varela, M., Burghardt, R., Hayashi, K., Farmer, J., and Spencer, T. (2006) Endogenous retroviruses regulate periimplantation placental growth and differentiation. Proceedings of the National Academy of Sciences of the United States of America, 103(39), pp. 14390-14395. (doi:10.1073/pnas.0603836103)

Palmarini, M. (2006) Ovine endogenous betaretroviruses (enJSRVs) and placental morphogenesis. Placenta, 27 Sup, S135-S140.

Varela, M., Chow, Y.H., Sturkie, C., Murcia, P.R., and Palmarini, M. (2006) Association of RON tyrosine kinase with the Jaagsiekte sheep retrovirus envelope glycoprotein. Virology, 350(2), pp. 347-357. (doi:10.1016/j.virol.2006.01.040)

2005

Caporale, M., Centorame, P., Giovannini, A., Sacchini, F., Di Ventura, M., De las Heras, M., and Palmarini, M. (2005) Infection of lung epithelial cells and induction of pulmonary adenocarcinoma is not the most common outcome of naturally occurring JSRV infection during the commercial lifespan of sheep. Virology, 338, pp. 144-153. (doi:10.1016/j.virol.2005.05.018)

Dunlap, K., Palmarini, M., Adelson, D., and Spencer, T. (2005) Sheep endogenous betaretroviruses (enJSRVs) and the hyaluronidase 2 (HYAL2) receptor in the ovine uterus and conceptus. Biology of Reproduction, 73, pp. 271-279. (doi:10.1095/biolreprod.105.039776)

Palmarini, M. (2005) A Moloney murine leukemia virus driven by the Jaagsiekte sheep retrovirus enhancers shows enhanced specificity for infectivity in lung epithelial cells. Virus Genes, 31(3), pp. 257-263.

2004

Cousens, C., Bishop, J.V., Philbey, A.W., Gill, C.A., Palmarini, M., Carlson, J.O., DeMartini, J.C., and Sharp, J.M. (2004) Analysis of integration sites of Jaagsiekte sheep retrovirus in ovine pulmonary adenocarcinoma. Journal of Virology, 78(16), pp. 8506-8512. (doi:10.1128/JVI.78.16.8506-8512.2004)

Mura, M., Murcia, P.R., Caporale, M., Spencer, T.E., Nagashima, K., Rein, A., and Palmarini, M. (2004) Late viral interference induced by transdominant Gag of an endogenous retrovirus. Proceedings of the National Academy of Sciences of the United States of America, 101(30), pp. 11117-11122. (doi:10.1073/pnas.0402877101)

Palmarini, M., Mura, M., and Spencer, T.E. (2004) Endogenous betaretroviruses of sheep: teaching new lessons in retroviral interference and adaptation. Journal of General Virology, 85(1), pp. 1-13. (doi:10.1099/vir.0.19547-0)

2003

Chow, Y.H.J., Alberti, A., Mura, M., Pretto, C., Murcia, P.R., Albritton, L.M., and Palmarini, M. (2003) Transformation of rodent fibroblasts by the Jaagsiekte sheep retrovirus envelope is receptor independent and does not require the surface domain. Journal of Virology, 77(11), pp. 6341-6350. (doi:10.1128/JVI.77.11.6341-6350.2003)

Spencer, T.E., Mura, M., Allison Gray, C., Griebel, P.J., and Palmarini, M. (2003) Receptor usage and fetal expression of ovine endogenous betaretroviruses: implications for coevolution of endogenous and exogenous retroviruses. Journal of Virology, 77(1), pp. 749-753. (doi:10.1128/JVI.77.1.749-753.2003)

Palmarini, M. (2003) Endogenous retroviruses related to jaagsiekte sheep retrovirus. Current Topics in Microbiology and Immunology, 275(.), pp. 117-137.

Palmarini, M. (2003) Molecular biology of jaagsiekte sheep retrovirus. Current Topics in Microbiology and Immunology, 275(.), pp. 81-115.

Palmarini, M. (2003) Receptor usage and fetal expression of ovine endogenous betaretroviruses: implications for coevolution of endogenous and exogenous retroviruses. Journal of Virology, 77(1), pp. 749-753.

Palmarini, M. (2003) Relevance of Akt phosphorylation in cell transformation induced by Jaagsiekte sheep retrovirus. Virology, 312(1), pp. 95-105.

Palmarini, M. (2003) Transformation and oncogenesis by jaagsiekte sheep retrovirus. Current Topics in Microbiology and Immunology, 275, pp. 139-177.

2002

Alberti, A., Murgia, C., Liu, S., Cousens, C., Sharp, M., Miller, A.D., and Palmarini, M. (2002) Envelope-induced cell transformation by ovine betaretroviruses. Journal of Virology, 76(11), pp. 5387-5394. (doi:10.1128/JVI.76.11.5387-5394.2002)

Palmarini, M. (2002) HNF-3beta is a critical factor for the expression of the Jaagsiekte sheep retrovirus long terminal repeat in type II pneumocytes but not in Clara cells. Virology, 292(1), pp. 87-97.

Palmarini, M. (2002) Spliced and prematurely polyadenylated Jaagsiekte sheep retrovirus-specific RNAs from infected or transfected cells. Virology, 294(1), pp. 180-188.

2001

Palmarini, M., Allison Gray, C., Carpenter, K., Fan, H., Bazer, F.W., and Spencer, T.E. (2001) Expression of endogenous betaretroviruses in the ovine uterus: effects of neonatal age, estrous cycle, pregnancy, and progesterone. Journal of Virology, 75(23), pp. 11319-11327. (doi:10.1128/JVI.75.23.11319-11327.2001)

Palmarini, M., Maeda, N., Murgia, C., De-Fraja, C., Hofacre, A., and Fan, H. (2001) A phosphatidylinositol 3-kinase docking site in the cytoplasmic tail of the Jaagsiekte sheep retrovirus transmembrane protein is essential for envelope-induced transformation of NIH 3T3 cells. Journal of Virology, 75(22), pp. 11002-11009. (doi:10.1128/JVI.75.22.11002-11009.2001)

Maeda, N., Palmarini, M., Murgia, C., and Fan, H. (2001) Direct transformation of rodent fibroblasts by jaagsiekte sheep retrovirus DNA. Proceedings of the National Academy of Sciences of the United States of America, 98(8), pp. 4449-4454. (doi:10.1073/pnas.071547598)

Palmarini, M. (2001) Association of jaagsiekte sheep retrovirus with pulmonary carcinoma in Sardinian moufflon (Ovis musimon). Journal of Comparative Pathology, 125(02-Mar), pp. 145-152.

Palmarini, M. (2001) Retrovirus-induced ovine pulmonary adenocarcinoma, an animal model for lung cancer. Journal of the National Cancer Institute, 93(21), pp. 1603-1614.

2000

Palmarini, M., Hallwirth, C., York, D., Murgia, C., and de Oliveira, T. (2000) Molecular cloning and functional analysis of three type D endogenous retroviruses of sheep reveal a different cell tropism from that of the highly related exogenous Jaagsiekte sheep retrovirus. Journal of Virology, 74(17), pp. 8065-8076.

De las Heras, M., Barsky, S.H., Hasleton, P., Wagner, M., Larson, E., Egan, J., Ortin, A., Gimenez-Mas, J.A., Palmarini, M., and Sharp, J.M. (2000) Evidence for a protein related immunologically to the jaagsiekte sheep retrovirus in some human lung tumours. European Respiratory Journal, 16(2), pp. 330-332. (doi:10.1034/j.1399-3003.2000.16b23.x)

Palmarini, M., Datta, S., Omid, R., Murgia, C., and Fan, H. (2000) The long terminal repeat of Jaagsiekte sheep retrovirus is preferentially active in differentiated epithelial cells of the lungs. Journal of Virology, 74(13), pp. 5776-5787.

Rosati, S., Pittau, M., Alberti, A., Pozzi, S., York, D.F., Sharp, J.M., and Palmarini, M. (2000) An accessory open reading frame (orf-x) of jaagsiekte sheep retrovirus is conserved between different virus isolates. Virus Research, 66(1), pp. 109-116. (doi:10.1016/S0168-1702(99)00118-5)

1999

Palmarini, M., Sharp, J.M., de las Heras, M., and Fan, H. (1999) Jaagsiekte sheep retrovirus is necessary and sufficient to induce a contagious lung cancer in sheep. Journal of Virology, 73(8), pp. 6964-6972.

Holland, M.J., Palmarini, M., Garcia-Goti, M., Gonzalez, L., McKendrick, I., De Las Heras, M., and Sharp, J.M. (1999) Jaagsiekte retrovirus is widely distributed both in T and B lymphocytes and in mononuclear phagocytes of sheep with naturally and experimentally acquired pulmonary adenomatosis. Journal of Virology, 73(5), pp. 4004-4008.

1998

Ortı́n, A., Minguijón, E., Dewar, P., Garcı́a, M., Ferrer, L. M., Palmarini, M., Gonzalez, L., Sharp, J. M., and De las Heras, M. (1998) Lack of a specific immune response against a recombinant capsid protein of Jaagsiekte sheep retrovirus in sheep and goats naturally affected by enzootic nasal tumour or sheep pulmonary adenomatosis. Veterinary Immunology and Immunopathology, 61(2-4), pp. 229-237. (doi:10.1016/S0165-2427(97)00149-9)

1996

Palmarini, M., Holland, M. J., Cousens, C., Dalziel, R. G., and Sharp, M. (1996) Jaagsiekte retrovirus establishes a disseminated infection of the lymphoid tissues of sheep affected by pulmonary adenomatosis. Journal of General Virology, 77(12), pp. 2991-2998. (doi:10.1099/0022-1317-77-12-2991)

Cousens, C., Minguijon, E., Garcia, M., Ferrer, L.M., Dalziel, R.G., Palmarini, M., De las Heras, M., and Sharp, J.M. (1996) PCR-based detection and partial characterization of a retrovirus associated with contagious intranasal tumors of sheep and goats. Journal of Virology, 70(11), pp. 7580-7583.

Palmarini, M., Cousens, C., Dalziel, R.G., Bai, J., Stedman, K., DeMartini, J.C., and Sharp, J.M. (1996) The exogenous form of Jaagsiekte retrovirus is specifically associated with a contagious lung cancer of sheep. Journal of Virology, 70(3), pp. 1618-1623.

1995

Palmarini, M., Dewar, P., De las Heras, M., Inglis, N. F., Dalziel, R.G., and Sharp, J.M. (1995) Epithelial tumour cells in the lungs of sheep with pulmonary adenomatosis are major sites of replication for Jaagsiekte retrovirus. Journal of General Virology, 76(11), pp. 2731-2737. (doi:10.1099/0022-1317-76-11-2731)

1994

Palmarini, M., Mughetti, L., Tollis, M., Alunni, L., and Vitellozzi, G. (1994) Il tumore intranasale enzootico della capra. Summa, 4, pp. 49-53.

1993

Palmarini, M., Farina, L., Cancellotti, F.M., and Macri, A. (1993) Utilizzazione dei reflui zootecnici in agricoltura: problemi igienico-sanitari. In: Rapporti Istisan 93/18. Istituto Superiore di Sanità: Italy.

Vitellozzi, G., Mughetti, L., Palmarini, M., Mandara, M. T., Mechelli, L., Sharp, J. M., and Manocchio, I. (1993) Enzootic intranasal tumour of goats in Italy. Journal of Veterinary Medicine, Series B, 40(1-10), pp. 459-468. (doi:10.1111/j.1439-0450.1993.tb00164.x)

This list was generated on Wed May 25 04:02:22 2016 BST.
Number of items: 95.

Articles

Ratinier, M., Shaw, A. E., Barry, G., Gu, Q., Di Gialleonardo, L., Janowicz, A., Varela, M., Randall, R. E., Caporale, M., and Palmarini, M. (2016) Bluetongue virus NS4 protein is an interferon antagonist and a determinant of virus virulence. Journal of Virology, (doi:10.1128/JVI.00422-16) (PMID:27009961) (Early Online Publication)

Varela, M. et al. (2016) Mutations in the Schmallenberg virus Gc glycoprotein facilitate cellular protein synthesis shutoff and restore pathogenicity of NSs deletion mutants in mice. Journal of Virology, (doi:10.1128/JVI.00424-16) (PMID:26984728) (Early Online Publication)

Stewart, M. et al. (2015) Characterisation of a second open reading frame in genome segment 10 of bluetongue virus. Journal of General Virology, 96(11), pp. 3280-3293. (doi:10.1099/jgv.0.000267) (PMID:26290332)

Ftaich, N. et al. (2015) Turnover rate of NS3 proteins modulates bluetongue virus replication kinetics in a host-specific manner. Journal of Virology, 89(20), pp. 10467-10481. (doi:10.1128/jvi.01541-15) (PMID:26246581)

Nomikou, K., Hughes, J., Wash, R., Kellam, P., Breard, E., Zientara, S., Palmarini, M., Biek, R., and Mertens, P. (2015) Widespread reassortment shapes the evolution and epidemiology of bluetongue virus following European invasion. PLoS Pathogens, 11(8), e1005056. (doi:10.1371/journal.ppat.1005056) (PMID:26252219) (PMCID:PMC4529188)

Janowicz, A., Caporale, M., Shaw, A., Gulletta, S., Di Gialleonardo, L., Ratinier, M., and Palmarini, M. (2015) Multiple genome segments determine virulence of bluetongue virus serotype 8. Journal of Virology, 89(10), pp. 5238-5249. (doi:10.1128/JVI.00395-15) (PMID:25822026) (PMCID:PMC4442542)

Murphy, L. et al. (2015) The sheep tetherin paralog oBST2B blocks envelope glycoprotein incorporation into nascent retroviral virions. Journal of Virology, 89(1), pp. 535-544. (doi:10.1128/JVI.02751-14)

Blomström, A.-L. et al. (2015) Transcriptome analysis reveals the host response to Schmallenberg virus in bovine cells and antagonistic effects of the NSs protein. BMC Genomics, 16, 324. (doi:10.1186/s12864-015-1538-9) (PMID:25896169) (PMCID:PMC4404599)

Brennan, B. et al. (2015) In memoriam – Richard M. Elliott (1954–2015). Journal of General Virology, 96(8), pp. 1975-1978. (doi:10.1099/jgv.0.000241) (PMID:26315040)

Nunes, S. F., Hamers, C., Ratinier, M., Shaw, A., Brunet, S., Hudelet, P., and Palmarini, M. (2014) A synthetic biology approach for a vaccine platform against known and newly emerging serotypes of bluetongue virus. Journal of General Virology, 29(7), pp. 912-920. (doi:10.1128/JVI.02183-14) (PMID:25142610) (PMCID:PMC4248921)

Caporale, M., Di Gialleonorado, L., Janowicz, A., Wilkie, G., Shaw, A., Savini, G., Van Rijn, P. A., Mertens, P., Di Ventura, M., and Palmarini, M. (2014) Virus and host factors affecting the clinical outcome of bluetongue virus infection. Journal of Virology, 88(18), pp. 10399-10411. (doi:10.1128/JVI.01641-14)

Barry, G. et al. (2014) NSs protein of Schmallenberg virus counteracts the antiviral response of the cell by inhibiting its transcriptional machinery. Journal of General Virology, 95(Pt. 8), pp. 1640-1646. (doi:10.1099/vir.0.065425-0)

Seehusen, F. et al. (2014) Skeletal muscle hypoplasia represents the only significant lesion in peripheral organs of ruminants infected with schmallenberg virus during gestation. Journal of Comparative Pathology, 151(2-3), pp. 148-152. (doi:10.1016/j.jcpa.2014.04.006)

Palmarini, M. (2014) Bluetongue: A rich history filled with many landmarks in virology……and more to be uncovered! Virus Research, 182, pp. 3-4. (doi:10.1016/j.virusres.2014.02.015)

Gerhauser, I., Weigand, M., Hahn, K., Herder, V., Wohlsein, P., Habierski, A., Varela, M., Palmarini, M., and Baumgärtner, W. (2014) Lack of Schmallenberg virus in ruminant brain tissues archived from 1961 to 2010 in Germany. Journal of Comparative Pathology, 150(2-3), pp. 151-154. (doi:10.1016/j.jcpa.2013.11.210)

Armezzani, A., Varela, M., Spencer, T., Palmarini, M., and Arnaud, F. (2014) "Ménage à Trois": the evolutionary interplay between JSRV, enJSRVs and domestic sheep. Viruses, 6(12), pp. 4926-4945. (doi:10.3390/v6124926)

Caporale, M. et al. (2013) Host species barriers to jaagsiekte sheep retrovirus replication and carcinogenesis. Journal of Virology, 87(19), pp. 10752-10762. (doi:10.1128/JVI.01472-13)

Schnettler, E., Ratinier, M., Watson, M., Shaw, A. E., McFarlane, M., Varela, M., Elliott, R. M., Palmarini, M., and Kohl, A. (2013) RNA interference targets arbovirus replication in Culicoides cells. Journal of Virology, 87(5), pp. 2441-2454. (doi:10.1128/JVI.02848-12) (PMID:23269795) (PMCID:PMC3571378)

Shaw, A.E. et al. (2013) Reassortment between two serologically unrelated bluetongue virus strains is flexible and can involve any genome segment. Journal of Virology, 87(1), pp. 543-557. (doi:10.1128/JVI.02266-12)

Herder, V., Hansmann, F., Wohlsein, P., Peters, M., Varela, M., Palmarini, M., and Baumgärtner, W. (2013) Immunophenotyping of inflammatory cells associated with schmallenberg virus infection of the central nervous system of ruminants. PLoS ONE, 8(5), e62939. (doi:10.1371/journal.pone.0062939)

Martineau, H.M., Dagleish, M.P., Cousens, C., Underwood, C., Forbes, V., Palmarini, M., and Griffiths, D.I. (2013) Cellular differentiation and proliferation in the ovine lung during gestation and early postnatal development. Journal of Comparative Pathology, 149(2-3), pp. 255-267. (doi:10.1016/j.jcpa.2012.11.239)

Rasmussen, L., Savini, G., Lorusso, A., Bellacicco, A., Palmarini, M., Caporale, M., Rasmussen, T., Belsham, G.J., and Bøtner, A. (2013) Transplacental transmission of field and rescued strains of BTV-2 and BTV-8 in experimentally infected sheep. Veterinary Research, 44(75), (doi:10.1186/1297-9716-44-75)

Shaw, A.E., Mellor, D.J., Purse, B.V., Shaw, P.E., McCorkell, B.F., and Palmarini, M. (2013) Transmission of Schmallenberg virus in a housed dairy herd in the UK. Veterinary Record, 173(24), p. 609. (doi:10.1136/vr.101983)

Varela, M. et al. (2013) Schmallenberg virus pathogenesis, tropism and interaction with the innate immune system of the host. PLoS Pathogens, 9(1), e1003133. (doi:10.1371/journal.ppat.1003133) (PMID:23326235) (PMCID:PMC3542112)

Shaw, A.E. et al. (2012) Drosophila melanogaster as a model organism for bluetongue virus replication and tropism. Journal of Virology, 86(17), pp. 9015-9024. (doi:10.1128/JVI.00131-12) (PMID:22674991) (PMCID:PMC3416142)

Spencer, T.E., and Palmarini, M. (2012) Application of next generation sequencing in mammalian embryogenomics: lessons learned from endogenous betaretroviruses of sheep. Animal Reproduction Science, 134(1-2), pp. 95-103. (doi:10.1016/j.anireprosci.2012.08.016)

Spencer, T.E., and Palmarini, M. (2012) Endogenous retroviruses of sheep: a model system for understanding physiological adaptation to an evolving ruminant genome. Journal of Reproduction and Development, 58(1), pp. 33-37. (doi:10.1262/jrd.2011-026)

Caporale, M. et al. (2011) Determinants of bluetongue virus virulence in murine models of disease. Journal of Virology, 85(21), pp. 11479-11489. (doi:10.1128/JVI.05226-11)

Armezzani, A., Arnaud, F., Caporale, M., di Meo, G., Iannuzzi, L., Murgia, C., and Palmarini, M. (2011) The Signal Peptide of a Recently Integrated Endogenous Sheep Betaretrovirus Envelope Plays a Major Role in Eluding Gag-Mediated Late Restriction. Journal of Virology, 85(14), pp. 7118-7128. (doi:10.1128/JVI.00407-11)

Murgia, C., Ceesay, O., Caporale, M., Di Francesco, G., Ferri, N., Varasano, V., de las Heras, M., and Palmarini, M. (2011) Lung adenocarcinoma originates from retrovirus infection of proliferating type 2 pneumocytes during pulmonary post-natal development or tissue repair. PLoS Pathogens, 7(3), e1002014. (doi:10.1371/journal.ppat.1002014)

Ratinier, M. et al. (2011) Identification and characterization of a novel non-structural protein of bluetongue virus. PLoS Pathogens, 7(12), e1002477. (doi:10.1371/journal.ppat.1002477) (PMID:22241985) (PMCID:PMC3248566)

Black, S.G. et al. (2010) Viral particles of endogenous betaretroviruses are released in the sheep uterus and infect the conceptus trophectoderm in a transspecies embryo transfer model. Journal of Virology, 84(18), pp. 9078-9085. (doi:10.1128/JVI.00950-10)

Arnaud, F., Black, S.G., Murphy, L., Griffiths, D.J., Neil, S.J., Spencer, T.E., and Palmarini, M. (2010) Interplay between ovine bone marrow stromal cell antigen 2/tetherin and endogenous retroviruses. Journal of Virology, 84(9), pp. 4415-4425. (doi:10.1128/JVI.00029-10)

Black, S.G., Arnaud, F., Palmarini, M., and Spencer, T.E. (2010) Endogenous Retroviruses in Trophoblast Differentiation and Placental Development. American Journal of Reproductive Immunology, 64(4), pp. 255-264. (doi:10.1111/j.1600-0897.2010.00860.x)

Miyazawa, T., Yoshikawa, R., Golder, M., Okada, M., Stewart, H., and Palmarini, M. (2010) Isolation of an Infectious Endogenous Retrovirus in a Proportion of Live Attenuated Vaccines for Pets. Journal of Virology, 84(7), pp. 3690-3694. (doi:10.1128/JVI.02715-09)

Spencer, T.E., Black, S.G., Arnaud, F., and Palmarini, M. (2010) Endogenous retroviruses of sheep: a model system for understanding physiological adaptation to an evolving ruminant genome. Society of Reproduction and Fertility Supplement, 67, pp. 95-104.

Varela, M., and Palmarini, M. (2010) Multitasking: Making the Most out of the Retroviral Envelope. Viruses, 2(8), pp. 1571-1576. (doi:10.3390/v2081571)

Chessa, B. et al. (2009) Revealing the history of sheep domestication using retrovirus integrations. Science, 324(5926), pp. 532-536. (doi:10.1126/science.1170587)

Caporale, M., Arnaud, F., Mura, M., Golder, M., Murgia, C., and Palmarini, M. (2009) The Signal Peptide of a Simple Retrovirus Envelope Functions as a Posttranscriptional Regulator of Viral Gene Expression. Journal of Virology, 83(9), pp. 4591-4604. (doi:10.1128/JVI.01833-08)

Heslin, D.J., Murcia, P., Arnaud, F., Van Doorslaer, K., Palmarini, M., and Lenz, J. (2009) A single amino acid substitution in a segment of the CA protein within gag that has similarity to human immunodeficiency virus type 1 blocks infectivity of a human endogenous retrovirus K provirus in the human genome. Journal of Virology, 83(2), (doi:10.1128/JVI.01439-08)

Mortuza, G.B., Goldstone, D.C., Pashley, C., Haire, L.F., Palmarini, M., Taylor, W.R., Stoye, J.P., and Taylor, I.A. (2009) Structure of the capsid amino-terminal domain from the betaretrovirus, jaagsiekte sheep retrovirus. Journal of Molecular Biology, 386(4), pp. 1179-1192. (doi:10.1016/j.jmb.2008.10.066)

Arnaud, F., Varela, M., Spencer, T.E., and Palmarini, M. (2008) Coevolution of endogenous Betaretroviruses of sheep and their host. Cellular and Molecular Life Sciences, 65(21), pp. 3422-3432. (doi:10.1007/s00018-008-8500-9)

Palmarini, M. (2008) A large animal model to evaluate the effects of Hsp90 inhibitors for the treatment of lung adenocarcinoma. Virology, 371(1), pp. 206-215. (doi:10.1016/j.virol.2007.09.041)

De Las Heras Guillamon, M., Murcia, P., Ortín, A., Azúa, J., Borderías, L., Álvarez, R., Jiménez-Más, J. A., Marchetti, A., and Palmarini, M. (2007) Jaagsiekte sheep retrovirus is not detected in human lung adenocarcinomas expressing antigens related to the Gag polyprotein of betaretrovirus. Cancer Letters, 258(1), pp. 22-30. (doi:10.1016/j.canlet.2007.08.006) (PMID:17889995)

Arnaud, F. et al. (2007) A paradigm for virus-host coevolution: sequential counter-adaptations between endogenous and exogenous retroviruses. PLoS Pathogens, 3(11), e170. (doi:10.1371/journal.ppat.0030170)

Arnaud, F., Murcia, P.R., and Palmarini, M. (2007) Mechanisms of late restriction induced by an endogenous retrovirus. Journal of Virology, 81(20), pp. 11441-11451. (doi:10.1128/JVI.01214-07)

Cousens, C., Maeda, N., Murgia, C., Dagleish, M., Palmarini, M., and Fan, H. (2007) In vivo tumorigenesis by Jaagsiekte sheep retrovirus (JSRV) requires Y590 in Env TM, but not full-length orfX open reading frame. Virology, 367, pp. 413-421. (doi:10.1016/j.virol.2007.06.004)

Murcia, P.R., Arnaud, F., and Palmarini, M. (2007) The transdominant endogenous retrovirus enJS56A1 associates with and blocks intracellular trafficking of Jaagsiekte sheep retrovirus Gag. Journal of Virology, 81(4), pp. 1762-1772. (doi:10.1128/JVI.01859-06)

Nolan, A., and Palmarini, M. (2007) Requirements for veterinary research and the recruitment of veterinary surgeons into research. Veterinary Record, 161(11), pp. 368-370. (doi:10.1136/vr.161.11.368)

Palmarini, M. (2007) A veterinary twist on pathogen biology. PLoS Pathogens, 3(2), e12. (doi:10.1371/journal.ppat.0030012)

Spencer, T., Johnson, G., Bazer, F., Burghardt, R., and Palmarini, M. (2007) Pregnancy recognition and conceptus implantation in domestic ruminants: Roles of progesterone, interferons and endogenous retroviruses. Reproduction Fertility and Development, 19, pp. 65-78. (doi:10.1071/RD06102)

Caporale, M., Cousens, C., Centorame, P., Pinoni, C., De Las Heras Guillamon, M., and Palmarini, M. (2006) Expression of the Jaagsiekte sheep retrovirus envelope glycoprotein is sufficient to induce lung tumors in sheep. Journal of Virology, 80(16), pp. 8030-8037. (doi:10.1128/JVI.00474-06)

Dunlap, K., Palmarini, M., Varela, M., Burghardt, R., Hayashi, K., Farmer, J., and Spencer, T. (2006) Endogenous retroviruses regulate periimplantation placental growth and differentiation. Proceedings of the National Academy of Sciences of the United States of America, 103(39), pp. 14390-14395. (doi:10.1073/pnas.0603836103)

Palmarini, M. (2006) Ovine endogenous betaretroviruses (enJSRVs) and placental morphogenesis. Placenta, 27 Sup, S135-S140.

Varela, M., Chow, Y.H., Sturkie, C., Murcia, P.R., and Palmarini, M. (2006) Association of RON tyrosine kinase with the Jaagsiekte sheep retrovirus envelope glycoprotein. Virology, 350(2), pp. 347-357. (doi:10.1016/j.virol.2006.01.040)

Caporale, M., Centorame, P., Giovannini, A., Sacchini, F., Di Ventura, M., De las Heras, M., and Palmarini, M. (2005) Infection of lung epithelial cells and induction of pulmonary adenocarcinoma is not the most common outcome of naturally occurring JSRV infection during the commercial lifespan of sheep. Virology, 338, pp. 144-153. (doi:10.1016/j.virol.2005.05.018)

Dunlap, K., Palmarini, M., Adelson, D., and Spencer, T. (2005) Sheep endogenous betaretroviruses (enJSRVs) and the hyaluronidase 2 (HYAL2) receptor in the ovine uterus and conceptus. Biology of Reproduction, 73, pp. 271-279. (doi:10.1095/biolreprod.105.039776)

Palmarini, M. (2005) A Moloney murine leukemia virus driven by the Jaagsiekte sheep retrovirus enhancers shows enhanced specificity for infectivity in lung epithelial cells. Virus Genes, 31(3), pp. 257-263.

Cousens, C., Bishop, J.V., Philbey, A.W., Gill, C.A., Palmarini, M., Carlson, J.O., DeMartini, J.C., and Sharp, J.M. (2004) Analysis of integration sites of Jaagsiekte sheep retrovirus in ovine pulmonary adenocarcinoma. Journal of Virology, 78(16), pp. 8506-8512. (doi:10.1128/JVI.78.16.8506-8512.2004)

Mura, M., Murcia, P.R., Caporale, M., Spencer, T.E., Nagashima, K., Rein, A., and Palmarini, M. (2004) Late viral interference induced by transdominant Gag of an endogenous retrovirus. Proceedings of the National Academy of Sciences of the United States of America, 101(30), pp. 11117-11122. (doi:10.1073/pnas.0402877101)

Palmarini, M., Mura, M., and Spencer, T.E. (2004) Endogenous betaretroviruses of sheep: teaching new lessons in retroviral interference and adaptation. Journal of General Virology, 85(1), pp. 1-13. (doi:10.1099/vir.0.19547-0)

Chow, Y.H.J., Alberti, A., Mura, M., Pretto, C., Murcia, P.R., Albritton, L.M., and Palmarini, M. (2003) Transformation of rodent fibroblasts by the Jaagsiekte sheep retrovirus envelope is receptor independent and does not require the surface domain. Journal of Virology, 77(11), pp. 6341-6350. (doi:10.1128/JVI.77.11.6341-6350.2003)

Spencer, T.E., Mura, M., Allison Gray, C., Griebel, P.J., and Palmarini, M. (2003) Receptor usage and fetal expression of ovine endogenous betaretroviruses: implications for coevolution of endogenous and exogenous retroviruses. Journal of Virology, 77(1), pp. 749-753. (doi:10.1128/JVI.77.1.749-753.2003)

Palmarini, M. (2003) Endogenous retroviruses related to jaagsiekte sheep retrovirus. Current Topics in Microbiology and Immunology, 275(.), pp. 117-137.

Palmarini, M. (2003) Molecular biology of jaagsiekte sheep retrovirus. Current Topics in Microbiology and Immunology, 275(.), pp. 81-115.

Palmarini, M. (2003) Receptor usage and fetal expression of ovine endogenous betaretroviruses: implications for coevolution of endogenous and exogenous retroviruses. Journal of Virology, 77(1), pp. 749-753.

Palmarini, M. (2003) Relevance of Akt phosphorylation in cell transformation induced by Jaagsiekte sheep retrovirus. Virology, 312(1), pp. 95-105.

Palmarini, M. (2003) Transformation and oncogenesis by jaagsiekte sheep retrovirus. Current Topics in Microbiology and Immunology, 275, pp. 139-177.

Alberti, A., Murgia, C., Liu, S., Cousens, C., Sharp, M., Miller, A.D., and Palmarini, M. (2002) Envelope-induced cell transformation by ovine betaretroviruses. Journal of Virology, 76(11), pp. 5387-5394. (doi:10.1128/JVI.76.11.5387-5394.2002)

Palmarini, M. (2002) HNF-3beta is a critical factor for the expression of the Jaagsiekte sheep retrovirus long terminal repeat in type II pneumocytes but not in Clara cells. Virology, 292(1), pp. 87-97.

Palmarini, M. (2002) Spliced and prematurely polyadenylated Jaagsiekte sheep retrovirus-specific RNAs from infected or transfected cells. Virology, 294(1), pp. 180-188.

Palmarini, M., Allison Gray, C., Carpenter, K., Fan, H., Bazer, F.W., and Spencer, T.E. (2001) Expression of endogenous betaretroviruses in the ovine uterus: effects of neonatal age, estrous cycle, pregnancy, and progesterone. Journal of Virology, 75(23), pp. 11319-11327. (doi:10.1128/JVI.75.23.11319-11327.2001)

Palmarini, M., Maeda, N., Murgia, C., De-Fraja, C., Hofacre, A., and Fan, H. (2001) A phosphatidylinositol 3-kinase docking site in the cytoplasmic tail of the Jaagsiekte sheep retrovirus transmembrane protein is essential for envelope-induced transformation of NIH 3T3 cells. Journal of Virology, 75(22), pp. 11002-11009. (doi:10.1128/JVI.75.22.11002-11009.2001)

Maeda, N., Palmarini, M., Murgia, C., and Fan, H. (2001) Direct transformation of rodent fibroblasts by jaagsiekte sheep retrovirus DNA. Proceedings of the National Academy of Sciences of the United States of America, 98(8), pp. 4449-4454. (doi:10.1073/pnas.071547598)

Palmarini, M. (2001) Association of jaagsiekte sheep retrovirus with pulmonary carcinoma in Sardinian moufflon (Ovis musimon). Journal of Comparative Pathology, 125(02-Mar), pp. 145-152.

Palmarini, M. (2001) Retrovirus-induced ovine pulmonary adenocarcinoma, an animal model for lung cancer. Journal of the National Cancer Institute, 93(21), pp. 1603-1614.

Palmarini, M., Hallwirth, C., York, D., Murgia, C., and de Oliveira, T. (2000) Molecular cloning and functional analysis of three type D endogenous retroviruses of sheep reveal a different cell tropism from that of the highly related exogenous Jaagsiekte sheep retrovirus. Journal of Virology, 74(17), pp. 8065-8076.

De las Heras, M., Barsky, S.H., Hasleton, P., Wagner, M., Larson, E., Egan, J., Ortin, A., Gimenez-Mas, J.A., Palmarini, M., and Sharp, J.M. (2000) Evidence for a protein related immunologically to the jaagsiekte sheep retrovirus in some human lung tumours. European Respiratory Journal, 16(2), pp. 330-332. (doi:10.1034/j.1399-3003.2000.16b23.x)

Palmarini, M., Datta, S., Omid, R., Murgia, C., and Fan, H. (2000) The long terminal repeat of Jaagsiekte sheep retrovirus is preferentially active in differentiated epithelial cells of the lungs. Journal of Virology, 74(13), pp. 5776-5787.

Rosati, S., Pittau, M., Alberti, A., Pozzi, S., York, D.F., Sharp, J.M., and Palmarini, M. (2000) An accessory open reading frame (orf-x) of jaagsiekte sheep retrovirus is conserved between different virus isolates. Virus Research, 66(1), pp. 109-116. (doi:10.1016/S0168-1702(99)00118-5)

Palmarini, M., Sharp, J.M., de las Heras, M., and Fan, H. (1999) Jaagsiekte sheep retrovirus is necessary and sufficient to induce a contagious lung cancer in sheep. Journal of Virology, 73(8), pp. 6964-6972.

Holland, M.J., Palmarini, M., Garcia-Goti, M., Gonzalez, L., McKendrick, I., De Las Heras, M., and Sharp, J.M. (1999) Jaagsiekte retrovirus is widely distributed both in T and B lymphocytes and in mononuclear phagocytes of sheep with naturally and experimentally acquired pulmonary adenomatosis. Journal of Virology, 73(5), pp. 4004-4008.

Ortı́n, A., Minguijón, E., Dewar, P., Garcı́a, M., Ferrer, L. M., Palmarini, M., Gonzalez, L., Sharp, J. M., and De las Heras, M. (1998) Lack of a specific immune response against a recombinant capsid protein of Jaagsiekte sheep retrovirus in sheep and goats naturally affected by enzootic nasal tumour or sheep pulmonary adenomatosis. Veterinary Immunology and Immunopathology, 61(2-4), pp. 229-237. (doi:10.1016/S0165-2427(97)00149-9)

Palmarini, M., Holland, M. J., Cousens, C., Dalziel, R. G., and Sharp, M. (1996) Jaagsiekte retrovirus establishes a disseminated infection of the lymphoid tissues of sheep affected by pulmonary adenomatosis. Journal of General Virology, 77(12), pp. 2991-2998. (doi:10.1099/0022-1317-77-12-2991)

Cousens, C., Minguijon, E., Garcia, M., Ferrer, L.M., Dalziel, R.G., Palmarini, M., De las Heras, M., and Sharp, J.M. (1996) PCR-based detection and partial characterization of a retrovirus associated with contagious intranasal tumors of sheep and goats. Journal of Virology, 70(11), pp. 7580-7583.

Palmarini, M., Cousens, C., Dalziel, R.G., Bai, J., Stedman, K., DeMartini, J.C., and Sharp, J.M. (1996) The exogenous form of Jaagsiekte retrovirus is specifically associated with a contagious lung cancer of sheep. Journal of Virology, 70(3), pp. 1618-1623.

Palmarini, M., Dewar, P., De las Heras, M., Inglis, N. F., Dalziel, R.G., and Sharp, J.M. (1995) Epithelial tumour cells in the lungs of sheep with pulmonary adenomatosis are major sites of replication for Jaagsiekte retrovirus. Journal of General Virology, 76(11), pp. 2731-2737. (doi:10.1099/0022-1317-76-11-2731)

Palmarini, M., Mughetti, L., Tollis, M., Alunni, L., and Vitellozzi, G. (1994) Il tumore intranasale enzootico della capra. Summa, 4, pp. 49-53.

Vitellozzi, G., Mughetti, L., Palmarini, M., Mandara, M. T., Mechelli, L., Sharp, J. M., and Manocchio, I. (1993) Enzootic intranasal tumour of goats in Italy. Journal of Veterinary Medicine, Series B, 40(1-10), pp. 459-468. (doi:10.1111/j.1439-0450.1993.tb00164.x)

Book Sections

Armezzani, A., Murphy, L., Spencer, T. E., Palmarini, M., and Arnaud, F. (2012) The evolutionary interplay between exogenous and endogenous sheep betaretroviruses. In: Witzany, G. (ed.) Viruses: Essential Agents of Life. Springer Netherlands: Dordrecht, pp. 293-307. ISBN 9789400748989 (doi:10.1007/978-94-007-4899-6_15)

Dudley, J. P., Mertz, J. A., Bhadra, S., Palmarini, M., and Kozak, C. A. (2010) Endogenous retroviruses and cancer. In: Retroviruses and Insights into Cancer. Springer New York: New York, NY, pp. 119-162. ISBN 9780387095806 (doi:10.1007/978-0-387-09581-3_5)

Murcia, P., Donachie, W., and Palmarini, M. (2009) Viral pathogens of domestic animals and their impact on biology, medicine and agriculture. In: Schaechter, M. (ed.) Encyclopedia of Microbiology, Third Edition. Elsevier Inc., pp. 805-819. ISBN 9780123739445 (doi:10.1016/B978-012373944-5.00368-0)

Varela, M., Spencer, T.E., Palmarini, M., and Arnaud, F. (2009) Friendly viruses the special relationship between endogenous retroviruses and their host. In: Witzany, G. (ed.) Natural Genetic Engineering and Natural Genome Editing. Series: Annals of the New York Academy of Sciences (1178). New York Academy of Sciences, pp. 157-172. ISBN 9781573317658 (doi:10.1111/j.1749-6632.2009.05002.x)

Sharp, J.M., de las Heras, M., Spencer, T.E., and Palmarini, M. (2008) Jaagsiekte sheep retrovirus. In: Mahy, B. and van Regenmortel, M. (eds.) Encyclopedia of Virology, Third Edition. Elsevier Ltd.: Oxford, pp. 175-182. ISBN 9780123744104 (doi:10.1016/B978-012374410-4.00675-0)

Palmarini, M., Farina, L., Cancellotti, F.M., and Macri, A. (1993) Utilizzazione dei reflui zootecnici in agricoltura: problemi igienico-sanitari. In: Rapporti Istisan 93/18. Istituto Superiore di Sanità: Italy.

This list was generated on Wed May 25 04:02:22 2016 BST.

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