Professor Hugh Willison
- Emeritus (School of Infection & Immunity)
email:
Hugh.Willison@glasgow.ac.uk
University of Glasgow, G128TA
https://orcid.org/0000-0002-5997-1683Publications
2023
Cunningham, M. E. , McGonigal, R. , Barrie, J. A., Campbell, C. I., Yao, D. and Willison, H. J. (2023) Axolemmal nanoruptures arising from paranodal membrane injury induce secondary axon degeneration in murine Guillain-Barré syndrome. Journal of the Peripheral Nervous System, 28(1), pp. 17-31. (doi: 10.1111/jns.12532) (PMID:36710500)
Halstead, S. K. et al. (2023) Serum anti‐GM2 and anti‐GalNAc‐GD1a ganglioside IgG antibodies are biomarkers for immune‐mediated polyneuropathies in cats. Journal of the Peripheral Nervous System, 28(1), pp. 32-40. (doi: 10.1111/jns.12529) (PMID:36573790)
McGonigal, R. , Cunningham, M. E. , Smyth, D., Chou, M., Barrie, J. A., Wilkie, A., Campbell, C., Saatman, K. E., Lunn, M. and Willison, H. J. (2023) The endogenous calpain inhibitor calpastatin attenuates axon degeneration in murine Guillain-Barré syndrome. Journal of the Peripheral Nervous System, 28(1), pp. 4-16. (doi: 10.1111/jns.12520) (PMID:36335586)
2022
McGonigal, R. and Willison, H. J. (2022) The role of gangliosides in the organisation of the node of Ranvier examined in glycosyltransferase transgenic mice. Journal of Anatomy, 241(5), pp. 1259-1271. (doi: 10.1111/joa.13562) (PMID:34605014) (PMCID:PMC9558150)
Cunningham, M. E. , McGonigal, R. , Barrie, J. A., Yao, D. and Willison, H. J. (2022) Real time imaging of intra-axonal calcium flux in an explant mouse model of axonal Guillain-Barré syndrome. Experimental Neurology, 355, 114127. (doi: 10.1016/j.expneurol.2022.114127) (PMID:35640716) (PMCID:PMC7614209)
Leonhard, S. E. et al. (2022) An international perspective on preceding infections in Guillain-Barré syndrome: The IGOS-1000 cohort. Neurology, 99(12), e1299-e1313. (doi: 10.1212/WNL.0000000000200885) (PMID:35981895)
McGonigal, R. , Campbell, C. I., Barrie, J. A., Yao, D., Cunningham, M. E. , Crawford, C. L., Rinaldi, S., Rowan, E. G. and Willison, H. J. (2022) Schwann cell nodal membrane disruption triggers bystander axonal degeneration in a Guillain-Barré syndrome mouse model. Journal of Clinical Investigation, 132(14), e158524. (doi: 10.1172/JCI158524) (PMID:35671105) (PMCID:PMC9282931)
Crawford, C. L. et al. (2022) SARM1 depletion slows axon degeneration in a CNS model of neurotropic viral infection. Frontiers in Molecular Neuroscience, 15, 860410. (doi: 10.3389/fnmol.2022.860410) (PMID:35493328) (PMCID:PMC9043327)
Wilder-Smith, A. et al. (2022) The legacy of ZikaPLAN: a transnational research consortium addressing Zika. Global Health Action, 14(sup1), 2008139. (doi: 10.1080/16549716.2021.2008139) (PMID:35377284) (PMCID:PMC8986226)
Ndondo, A. P., Eley, B., Wilmshurst, J. M., Kakooza-Mwesige, A., Giannoccaro, M. P., Willison, H. J. , Cruz, P. M. R., Heckmann, J. M., Bateman, K. and Vincent, A. (2022) Post-infectious autoimmunity in the central (CNS) and peripheral (PNS) nervous systems: an African perspective. Frontiers in Immunology, 13, 833548. (doi: 10.3389/fimmu.2022.833548) (PMID:35356001) (PMCID:PMC8959857)
Halstead, S.K. et al. (2022) Serum anti-GM2 and anti-GalNAc-GD1a IgG antibodies are biomarkers for acute canine polyradiculoneuritis. Journal of Small Animal Practice, 63(2), pp. 104-112. (doi: 10.1111/jsap.13439) (PMID:34791652)
Halstead, S. K., Gourlay, D. and Willison, H. J. (2022) Detection of autoantibodies using combinatorial glycolipid microarrays. In: Kilcoyne, M. and Gerlach, J. Q. (eds.) Glycan Microarrays: Methods and Protocols. Series: Methods in Molecular Biology, 2460. Humana Press: New York, pp. 183-191. ISBN 9781071621479 (doi: 10.1007/978-1-0716-2148-6_11)
Campbell, C. I., McGonigal, R. , Barrie, J. A., Delaere, J., Bracke, L., Cunningham, M. E. , Yao, D., Delahaye, T., Van de Walle, I. and Willison, H. J. (2022) Complement inhibition prevents glial nodal membrane injury in a GM1 antibody-mediated mouse model. Brain Communications, 4(6), fcac306. (doi: 10.1093/braincomms/fcac306) (PMID:36523267) (PMCID:PMC9746686)
2021
Persson, B. D., Nord, S., Lindqvist, R., Danskog, K., Överby, A. K., Kohl, A. , Willison, H. J. , Lenman, A. and Arnberg, N. (2021) BAF45b Is required for efficient Zika virus infection of HAP1 cells. Viruses, 13(10), 2007. (doi: 10.3390/v13102007) (PMCID:PMC8540262)
Leonhard, S. E. et al. (2021) Guía basada en la evidencia. Diagnóstico y manejo del síndrome de Guillain-Barré en diez pasos = Evidence based guidelines. Diagnosis and management of Guillain-Barré syndrome in ten steps. Medicina, 81(5), pp. 817-836. (PMID:34633957)
Schultz, V. et al. (2021) Oligodendrocytes are susceptible to Zika virus infection in a mouse model of perinatal exposure: implications for CNS complications. Glia, 69(8), pp. 2023-2036. (doi: 10.1002/glia.24010) (PMID:33942402) (PMCID:PMC9216243)
McGonigal, R. , Barrie, J. A., Yao, D., Black, L. E. , McLaughlin, M. and Willison, H. J. (2021) Neuronally expressed a-series gangliosides are sufficient to prevent the lethal age-dependent phenotype in GM3-only expressing mice. Journal of Neurochemistry, 158(2), pp. 217-232. (doi: 10.1111/jnc.15365) (PMID:33864399)
Schultz, V. et al. (2021) Zika virus infection leads to demyelination and axonal injury in mature CNS cultures. Viruses, 13(1), 91. (doi: 10.3390/v13010091) (PMID:33440758) (PMCID:PMC7827345)
2020
Brito Ferreira, M. L. et al. (2020) Neurological disease in adults with Zika and chikungunya virus infection in Northeast Brazil: a prospective observational study. Lancet Neurology, 19(10), pp. 826-839. (doi: 10.1016/S1474-4422(20)30232-5) (PMID:32949543)
Cunningham, M. E. , Meehan, G. R. , Robinson, S., Yao, D., McGonigal, R. and Willison, H. J. (2020) Perisynaptic Schwann cells phagocytose nerve terminal debris in a mouse model of Guillain-Barré syndrome. Journal of the Peripheral Nervous System, 25(2), pp. 143-151. (doi: 10.1111/jns.12373) (PMID:32250537)
2019
Whitehead, M. J., McCanney, G., Willison, H. J. and Barnett, S. C. (2019) MyelinJ: an ImageJ macro for high throughput analysis of myelinating cultures. Bioinformatics, 35(21), pp. 4528-4530. (doi: 10.1093/bioinformatics/btz403) (PMID:31095292) (PMCID:PMC6821319)
Leonhard, S. E. et al. (2019) Diagnosis and management of Guillain-Barré syndrome in ten steps. Nature Reviews Neurology, 15, pp. 671-683. (doi: 10.1038/s41582-019-0250-9) (PMID:31541214) (PMCID:PMC6821638)
Nutma, E., Willison, H. , Martino, G. and Amor, S. (2019) Neuroimmunology - the past, present and future. Clinical and Experimental Immunology, 197(3), pp. 278-293. (doi: 10.1111/cei.13279) (PMID:30768789) (PMCID:PMC6693969)
Verboon, C. et al. (2019) Current treatment practice of Guillain-Barré syndrome. Neurology, 93(1), e59-e76. (doi: 10.1212/WNL.0000000000007719) (PMID:31175208)
McCanney, G. A., Mcgrath, M. A., Otto, T. D. , Burchmore, R. , Yates, E. A., Bavington, C. D., Willison, H. J. , Turnbull, J. E. and Barnett, S. C. (2019) Low sulfated heparins target multiple proteins for central nervous system repair. Glia, 67(4), pp. 668-687. (doi: 10.1002/glia.23562) (PMID:30585359)
McGonigal, R. , Barrie, J.A., Yao, D., McLaughlin, M. , Cunningham, M.E. , Rowan, E.G. and Willison, H.J. (2019) Glial sulfatides and neuronal complex gangliosides are functionally interdependent in maintaining myelinating axon integrity. Journal of Neuroscience, 39(1), pp. 63-77. (doi: 10.1523/JNEUROSCI.2095-18.2018) (PMID:30446529) (PMCID:PMC6325269)
McCanney, G. A., Lindsay, S. L. , McGrath, M. A., Willison, H. , Moss, C., Bavington, C. and Barnett, S. C. (2019) The use of myelinating cultures as a screen of glycomolecules for CNS repair. Biology, 8(3), 52. (doi: 10.3390/biology8030052) (PMID:31261710)
Wilder-Smith, A. et al. (2019) ZikaPLAN: addressing the knowledge gaps and working towards a research preparedness network in the Americas. Global Health Action, 12(1), 1666566. (doi: 10.1080/16549716.2019.1666566) (PMID:31640505) (PMCID:PMC6818126)
2018
Meehan, G. R. , McGonigal, R. , Cunningham, M. E. , Wang, Y., Barrie, J. A., Halstead, S. K., Gourlay, D., Yao, D. and Willison, H. J. (2018) Differential binding patterns of anti-sulfatide antibodies to glial membranes. Journal of Neuroimmunology, 323, pp. 28-35. (doi: 10.1016/j.jneuroim.2018.07.004) (PMID:30196830) (PMCID:PMC6134133)
Doets, A. Y. et al. (2018) Regional variation of Guillain-Barré syndrome. Brain, 141(10), pp. 2866-2877. (doi: 10.1093/brain/awy232) (PMID:30247567)
Leonhard, S. E., Lant, S., Jacobs, B. C., Wilder-Smith, A., Brito Ferreira, M. L., Solomon, T. and Willison, H. (2018) Zika virus infection in the returning traveller: what every neurologist should know. Practical Neurology, 18(4), pp. 271-277. (doi: 10.1136/practneurol-2017-001789) (PMID:29618586) (PMCID:PMC6204932)
Acosta-Ampudia, Y., Monsalve, D. M., Castillo-Medina, L. F., Rodríguez, Y., Pacheco, Y., Halstead, S., Willison, H. J. , Anaya, J.-M. and Ramírez-Santana, C. (2018) Autoimmune neurological conditions associated with Zika virus infection. Frontiers in Molecular Neuroscience, 11, 116. (doi: 10.3389/fnmol.2018.00116) (PMID:29695953) (PMCID:PMC5904274)
Whitehead, M. J., McGonigal, R. , Willison, H. J. and Barnett, S. C. (2018) Heparanase attenuates axon degeneration following sciatic nerve transection. Scientific Reports, 8, 5219. (doi: 10.1038/s41598-018-23070-6) (PMID:29581478) (PMCID:PMC5980233)
Fehmi, J., Scherer, S. S., Willison, H. J. and Rinaldi, S. (2018) Nodes, paranodes and neuropathies. Journal of Neurology, Neurosurgery and Psychiatry, 89(1), pp. 61-71. (doi: 10.1136/jnnp-2016-315480) (PMID:28819062)
Goodfellow, J. A. and Willison, H. J. (2018) Gangliosides and autoimmune peripheral nerve diseases. In: Gangliosides in Health and Disease. Series: Progress in Molecular Biology and Translational Science, 156. Elsevier, pp. 355-382. ISBN 9780128123416 (doi: 10.1016/bs.pmbts.2017.12.010)
Willison, H. J. (2018) Anti-ganglioside antibodies in peripheral nerve pathology. In: Sonnino, S. and Prinetti, A. (eds.) Gangliosides: Methods and Protocols. Series: Methods in molecular biology (1804). Humana Press: New York, NY, pp. 173-188. ISBN 9781493985517 (doi: 10.1007/978-1-4939-8552-4_7)
2017
Rupp, A. et al. (2017) The Sero-Prevalence of Anti-Glycolipid Antibodies in Acute Canine Polyradiculoneuritis and Other Peripheral and Cranial Neuropathies, Neuromuscular Disorders and Myopathies. 30th Annual Symposium of the European Society of Veterinary Neurology, Helsinki, Finland, 21-23 Sep 2017.
Cumberworth, S. L. et al. (2017) Zika virus tropism and interactions in myelinating neural cell cultures: CNS cells and myelin are preferentially affected. Acta Neuropathologica Communications, 5, 50. (doi: 10.1186/s40478-017-0450-8) (PMID:28645311) (PMCID:PMC5481922)
Jacobs, B. C. et al. (2017) International Guillain-Barré Syndrome Outcome Study (IGOS): protocol of a prospective observational cohort study on clinical and biological predictors of disease course and outcome in Guillain-Barré syndrome. Journal of the Peripheral Nervous System, 22(2), pp. 68-76. (doi: 10.1111/jns.12209) (PMID:28406555)
Kleinecke, S. et al. (2017) Peroxisomal dysfunctions cause lysosomal storage and axonal Kv1 channel redistribution in peripheral neuropathy. eLife, 6, e23332. (doi: 10.7554/elife.23332) (PMID:28470148) (PMCID:PMC5417850)
Clark, A. J., Kaller, M. S., Galino, J., Willison, H. J. , Rinaldi, S. and Bennett, D. L.H. (2017) Co-cultures with stem cell-derived human sensory neurons reveal regulators of peripheral myelination. Brain, 140(4), pp. 898-913. (doi: 10.1093/brain/awx012) (PMID:28334857) (PMCID:PMC5637940)
Davidson, A. I., Halstead, S. K., Goodfellow, J. A., Chavada, G., Mallik, A., Overell, J., Lunn, M. P., McConnachie, A. , van Doorn, P. and Willison, H. J. (2017) Inhibition of complement in Guillain-Barré Syndrome: the ICA-GBS study. Journal of the Peripheral Nervous System, 6, pp. 4-12. (doi: 10.1111/jns.12194) (PMID:27801990)
Wilder-Smith, A. et al. (2017) ZikaPLAN: Zika Preparedness Latin American Network. Global Health Action, 10(1), 1398485. (doi: 10.1080/16549716.2017.1398485) (PMID:29235414)
2016
Goodfellow, J. A. and Willison, H. J. (2016) Guillain-Barré syndrome: a century of progress. Nature Reviews Neurology, 12(12), pp. 723-731. (doi: 10.1038/nrneurol.2016.172) (PMID:27857121)
Halstead, S. K., Kalna, G., Islam, M. B., Jahan, I., Mohammad, Q. D., Jacobs, B. C., Endtz, H. P., Islam, Z. and Willison, H. J. (2016) Microarray screening of Guillain-Barré syndrome sera for antibodies to glycolipid complexes. Neurology: Neuroimmunology and Neuroinflammation, 3(6), e284. (doi: 10.1212/NXI.0000000000000284) (PMID:27790627)
Umapathi, T., Lim, C. S. J., Ooi, E. E., Zhang, S. L., Jin Hui Goh, E., Tan, H. C., Chng, K. Y. S. and Willison, H. (2016) Asymptomatic dengue infection may trigger Guillain-Barré syndrome. Journal of the Peripheral Nervous System, 21(4), pp. 375-377. (doi: 10.1111/jns.12190) (PMID:27717230)
Goodfellow, J. and Willison, H. (2016) Antiganglioside, antiganglioside-complex, and antiglycolipid-complex antibodies in immune-mediated neuropathies. Current Opinion in Neurology, 29(5), pp. 572-580. (doi: 10.1097/WCO.0000000000000361) (PMID:27427992)
Hughes, R. A.C., Cornblath, D. R. and Willison, H. J. (2016) Guillain-Barré syndrome in the 100 years since its description by Guillain, Barré and Strohl. Brain, 139(11), pp. 3041-3047. (doi: 10.1093/brain/aww247) (PMID:29106487)
Willison, H. J. , Jacobs, B. and van Doorn, P. (2016) Guillain-Barré syndrome. Lancet, 388(10045), pp. 717-727. (doi: 10.1016/s0140-6736(16)00339-1) (PMID:26948435)
Rupp, A. et al. (2016) Complement-fixing Anti-ganglioside Antibodies in Acute Canine Polyradiculoneuritis. PNS/Inflammatory Neuropathy Consortium Meeting, Glasgow, UK, 21-25 Jun 2016.
Cunningham, M. , McGonigal, R. , Meehan, G. R. , Barrie, J. A., Yao, D., Halstead, S. K. and Willison, H. J. (2016) Anti-ganglioside antibodies are removed from circulation in mice by neuronal endocytosis. Brain, 139(6), pp. 1657-1665. (doi: 10.1093/brain/aww056) (PMID:27017187) (PMCID:PMC4892750)
Cao-Lormeau, V.-M. et al. (2016) Guillain-Barré Syndrome outbreak associated with Zika virus infection in French Polynesia: a case-control study. Lancet, 387(10027), pp. 1531-1539. (doi: 10.1016/s0140-6736(16)00562-6) (PMID:26948433) (PMCID:PMC5444521)
Martini, R. and Willison, H. (2016) Neuroinflammation in the peripheral nerve: Cause, modulator, or bystander in peripheral neuropathies? Glia, 64(4), pp. 475-486. (doi: 10.1002/glia.22899) (PMID:26250643) (PMCID:PMC4832258)
Willison, H. J. and Goodfellow, J. A. (Eds.) (2016) GBS100: Celebrating a Century of Progress in Guillain-Barré Syndrome. Peripheral Nerve Society: San Diego, CA. ISBN 9780997510300
McGonigal, R. , Cunningham, M. E. , Yao, D., Barrie, J. A., Sankaranarayanan, S., Fewou, S. N., Furukawa, K., Yednock, T. A. and Willison, H. J. (2016) C1q-targeted inhibition of the classical complement pathway prevents injury in a novel mouse model of acute motor axonal neuropathy. Acta Neuropathologica Communications, 4, 23. (doi: 10.1186/s40478-016-0291-x) (PMID:26936605) (PMCID:PMC4776408)
2015
Feldman, E. L., Hughes, R. A.C. and Willison, H. (2015) Progress in inflammatory neuropathy :the legacy of Dr Jack Griffin. Nature Reviews Neurology, 11(11), pp. 646-650. (doi: 10.1038/nrneurol.2015.192) (PMID:26458287)
Rupp, A. et al. (2015) The Sero-prevalence of Anti-glycolipid Antibodies in Acute Canine Polyradiculoneuritis and Other Peripheral and Cranial Neuropathies, Neuromuscular Disorders and Myopathies – Interim Report. 28th Annual Symposium of the European Society of Veterinary Neurology and European College of Veterinary Neurology, Amsterdam, The Netherlands, 18 Sep 2015.
Delmont, E., Robb, H., Davidson, A., Halstead, S., Yao, D., Meehan, G. R. and Willison, H. (2015) Prospective study comparing enzyme-linked immunosorbent assay and glycoarray assay to detect antiglycolipid antibodies in a routine diagnostic neuroimmunology laboratory setting. Clinical and Experimental Neuroimmunology, 6(2), pp. 175-182. (doi: 10.1111/cen3.12193)
Delmont, E., Halstead, S., Galban-Horcajo, F., Yao, D., Desnuelle, C. and Willison, H. (2015) Improving the detection of IgM antibodies against glycolipids complexes of GM1 and galactocerebroside in multifocal motor neuropathy using glycoarray and ELISA assays. Journal of Neuroimmunology, 278, pp. 159-161. (doi: 10.1016/j.jneuroim.2014.11.001) (PMID:25468269)
Galban-Horcajo, F., Vlam, L., Delmont, E., Halstead, S. K., van den Berg, L., van der Pol, W.-L. and Willison, H. J. (2015) The diagnostic utility of determining anti-GM1: GalC complex antibodies in multifocal motor neuropathy: a validation study. Journal of Neuromuscular Diseases, 2(2), pp. 157-165. (doi: 10.3233/JND-150080) (PMID:27858734) (PMCID:PMC5271459)
2014
Galban-Horcajo, F., Halstead, S. K., McGonigal, R. and Willison, H. J. (2014) The application of glycosphingolipid arrays to autoantibody detection in neuroimmunological disorders. Current Opinion in Chemical Biology, 18, pp. 78-86. (doi: 10.1016/j.cbpa.2014.01.008)
Fewou, S.N., Plomp, J.J. and Willison, H.J. (2014) The pre-synaptic motor nerve terminal as a site for antibody-mediated neurotoxicity in autoimmune neuropathies and synaptopathies. Journal of Anatomy, 224(1), pp. 36-44. (doi: 10.1111/joa.12088)
Miller, J. A.L., Spyropoulos, A., Jaros, E., Galban-Horcajo, F., Whittaker, R. G. and Willison, H. J. (2014) Anti-GQ1b ganglioside positive Miller Fisher syndrome - evidence of paranodal pathology on nerve biopsy. Journal of Neuromuscular Diseases, 1(2), pp. 191-195. (doi: 10.3233/JND-140039) (PMID:27858774)
Willison, H. J. , Galban-Horcajo, F. and Halstead, S. K. (2014) Antibodies to GM1: galactocerebroside complexes in multifocal motor neuropathy: it takes two to tango. Journal of Neurology, Neurosurgery and Psychiatry, 85(7), p. 715. (doi: 10.1136/jnnp-2013-306050)
Yao, D. et al. (2014) Neuronal expression of galnac transferase is sufficient to prevent the age-related neurodegenerative phenotype of complex ganglioside-deficient mice. Journal of Neuroscience, 34(3), pp. 880-891. (doi: 10.1523/JNEUROSCI.3996-13.2014)
2013
Reindl, M. et al. (2013) Antibodies to heteromeric glycolipid complexes in Guillain-Barré syndrome. PLoS ONE, 8(12), e82337. (doi: 10.1371/journal.pone.0082337) (PMID:24358172) (PMCID:PMC3864991)
Willison, H.J. and Goodyear, C.S. (2013) Glycolipid antigens and autoantibodies in autoimmune neuropathies. Trends in Immunology, 34(9), pp. 453-459. (doi: 10.1016/j.it.2013.05.001)
Rupp, A., Cunningham, M. E. , Yao, D., Furukawa, K. and Willison, H. J. (2013) The effects of age and ganglioside composition on the rate of motor nerve terminal regeneration following antibody-mediated injury in mice. Synapse, 67(7), pp. 382-389. (doi: 10.1002/syn.21648) (PMID:23401234) (PMCID:PMC4495252)
Rupp, A., Yao, D., Meehan, G. R. and Willison, H. J. (2013) Thy-1 Mice Lend Themselves for the Modelling of Anti-ganglioside Antibody-mediated Disorders. PNS Biennial Meeting of the Peripheral Nerve Society, St Malo, France, 11-14 Jun 2013.
Rupp, A.F., Galban-Horcajo, F., Bianchi, E., Dondi, M., Penderis, J., Cappell, J., Burgess, K., Matiasek, K., McGonigal, R. and Willison, H.J. (2013) Anti-GM2 ganglioside antibodies are a biomarker for acute canine polyradiculoneuritis. Journal of the Peripheral Nervous System, 18(1), pp. 75-88. (doi: 10.1111/jns5.12011) (PMID:23521648)
Galban-Horcajo, F., Fitzpatrick, A.M., Hutton, A.J., Dunn, S.M., Kalna, G., Brennan, K.M., Rinaldi, S., Yu, R.K., Goodyear, C.S. and Willison, H.J. (2013) Antibodies to heteromeric glycolipid complexes in multifocal motor neuropathy. European Journal of Neurology, 20(1), pp. 62-70. (doi: 10.1111/j.1468-1331.2012.03767.x)
2012
Chavada, G. and Willison, H.J. (2012) Autoantibodies in immune-mediated neuropathies. Current Opinion in Neurology, 25(5), pp. 550-555. (doi: 10.1097/WCO.0b013e328357a77f)
Rupp, A., Galban-Horcajo, F., Bianchi, E., Dondi, M., Penderis, J., Galluci, A. and Willison, H. J. (2012) Anti-ganglioside Antibodies as a Diagnostic Marker in Acute Canine Polyradiculoneuritis. 25th Annual Symposium of the European Society of Veterinary Neurology and European College of Veterinary Neurology, Ghent, Belgium, 13-15 Sep 2012.
Willison, H.J. and Linington, C. (2012) Antibodies to MOG in NMO: a seasoned veteran finds a new role. Neurology, 79(12), pp. 1198-1199. (doi: 10.1212/WNL.0b013e31826aadaf)
Rupp, A., Galban-Horcajo, F., Bianchi, E., Dondi, M., Penderis, J. and Willison, H. J. (2012) Acute Canine Polyradiculoneuritis: A Naturally Occurring Model for Guillain-Barré Syndrome. PNS/Inflammatory Neuropathy Consortium Meeting, Rotterdam, The Netherlands, 24-27 Jun 2012.
Elliott, C. et al. (2012) Functional identification of pathogenic autoantibody responses in patients with multiple sclerosis. Brain, 135(6), pp. 1819-1833. (doi: 10.1093/brain/aws105)
Fewou, S. N., Rupp, A., Nickolay, L. E., Carrick, K., Greenshields, K. N., Pediani, J. , Plomp, J. J. and Willison, H. J. (2012) Anti-ganglioside antibody internalization attenuates motor nerve terminal injury in a mouse model of acute motor axonal neuropathy. Journal of Clinical Investigation, 122(3), pp. 1037-1051. (doi: 10.1172/JCI59110) (PMID:22307327) (PMCID:PMC3287221)
Huizinga, R. et al. (2012) Sialylation of campylobacter jejuni lipo-oligosaccharides: impact on phagocytosis and cytokine production in mice. PLoS ONE, 7(3), e34416. (doi: 10.1371/journal.pone.0034416) (PMID:22470569) (PMCID:PMC3314637)
Islam, Z. et al. (2012) Guillain-Barré Syndrome-related campylobacter jejuni in Bangladesh: ganglioside mimicry and cross-reactive antibodies. PLoS ONE, 7(8), e43976. (doi: 10.1371/journal.pone.0043976) (PMID:22952833) (PMCID:PMC3428305)
Rinaldi, S., Brennan, K.M. and Willison, H.J. (2012) Combinatorial glycoarray. Methods in Molecular Biology, 808, pp. 413-423. (doi: 10.1007/978-1-61779-373-8_28)
Rupp, A., Morrison, I., Barrie, J.A., Halstead, S.K., Townson, K.H., Greenshields, K.N. and Willison, H.J. (2012) Motor nerve terminal destruction and regeneration following anti-ganglioside antibody and complement-mediated injury: An in and ex vivo imaging study in the mouse. Experimental Neurology, 233(2), pp. 836-848. (doi: 10.1016/j.expneurol.2011.12.010)
2011
Rupp, A., Morrison, I., Greenshields, K. and Willison, H. J. (2011) Harnessing In Vivo Imaging to Investigate Immune-mediated Disorders of the Neuromuscular Junction. 11th Course of the European School of Neuroimmunology, Glasgow, UK, 04-07 Nov 2011.
Höke, A. and Willison, H.J. (2011) In memoriam: remembering John W. 'Jack' Griffin M.D. Nature Reviews Neurology, 7, pp. 361-362. (doi: 10.1038/nrneurol.2011.94)
Rupp, A., Morrison, I., Halstead, S. K., Townson, K. H., Greenshields, K. N. and Willison, H. J. (2011) Rapid Deterioration and Steady Recovery of the Motor Nerve Terminal Integrity Following Complemenet-mediated Injury in a Murine Model of Guillain-Barré Syndrome. PNS Biennial Meeting of the Peripheral Nerve Society, Potomac, MD, USA, 25-29 Jun 2011.
Barnett, M. H., Barnett, Y., Burke, D. and Willison, H. (2011) Spinal nerve root hypertrophy in chronic ataxic neuropathy with antiglycolipid IgM antibodies. Journal of Neurology, Neurosurgery and Psychiatry, 82(1), p. 97. (doi: 10.1136/jnnp.2010.205096)
Brennan, K.M. et al. (2011) Lipid arrays identify myelin-derived lipids and lipid complexes as prominent targets for oligoclonal band antibodies in multiple sclerosis. Journal of Neuroimmunology, 238(1-2), pp. 87-95. (doi: 10.1016/j.jneuroim.2011.08.002)
Fitzpatrick, A.M., Mann, C.A., Barry, S. , Brennan, K., Overell, J.R. and Willison, H.J. (2011) An open label clinical trial of complement inhibition in multifocal motor neuropathy. Journal of the Peripheral Nervous System, 16(2), pp. 84-91. (doi: 10.1111/j.1529-8027.2011.00328.x)
Hartung, H.-P., Lehmann, H.C. and Willison, H.J. (2011) Peripheral neuropathies: Establishing common clinical research standards for CIDP. Nature Reviews Neurology, 7(5), pp. 250-251. (doi: 10.1038/nrneurol.2011.46)
Nilsson, E.C. et al. (2011) The GD1a glycan is a cellular receptor for adenoviruses causing epidemic keratoconjunctivitis. Nature Medicine, 17(1), pp. 105-109. (doi: 10.1038/nm.2267)
Willison, H. (2011) Reply: Neurofascin as target of autoantibodies in Guillain-Barre syndrome. Brain, 134(5), e174-e174. (doi: 10.1093/brain/awq375)
Willison, H.J. (2011) Biomarkers in experimental models of antibody-mediated neuropathies. Journal of the Peripheral Nervous System, 16, pp. 60-62. (doi: 10.1111/j.1529-8027.2011.00310.x)
Zitman, F.M.P. et al. (2011) Neuropathophysiological potential of Guillain-Barré syndrome anti-ganglioside-complex antibodies at mouse motor nerve terminals. Clinical and Experimental Neuroimmunology, 2(3), pp. 59-67. (doi: 10.1111/j.1759-1961.2011.00022.x)
Zitman, F.M.P., Todorov, B., Verschuuren, J.J., Jacobs, B.C., Furukawa, K., Furukawa, K., Willison, H.J. and Plomp, J.J. (2011) Neuromuscular synaptic transmission in aged ganglioside-deficient mice. Neurobiology of Aging, 32(1), pp. 157-167. (doi: 10.1016/j.neurobiolaging.2009.01.007)
2010
Rupp, A. and Willison, H. J. (2010) Rapid Injury and Steady Recovery of the Neuromuscular Nerve Terminal Integrity After Application of Anti-ganglioside Antibody in a Murine Model of Guillain-Barré Syndrome. 10th International Congress of Neuroimmunology, Barcelona, Spain, 26-30 Oct 2010.
Rupp, A., Morrison, I., Halstead, S. K. and Willison, H. J. (2010) A Combination of In Vivo and Ex Vivo Imaging to Monitor Degeneration and Regeneration of the Murine Neuromuscular Junction Following Immune-mediated Injury. 23rd Annual Symposium of the European Society of Veterinary Neurology and European College of Veterinary Neurology, Cambridge, UK, 17-18 Sep 2010.
McGonigal, R. , Rowan, E.G., Greenshields, K.N., Halstead, S.K., Humphreys, P.D., Rother, R.P., Furukawa, K. and Willison, H.J. (2010) Anti-GD1a antibodies activate complement and calpain to injure distal motor nodes of Ranvier in mice. Brain, 133(7), pp. 1944-1960. (doi: 10.1093/brain/awq119)
Willison, H.J. (2010) Sugar refining reveals a further specificity for autoantibodies in multifocal motor neuropathy. Journal of Neurology, Neurosurgery and Psychiatry, 81(7), pp. 707-708. (doi: 10.1136/jnnp.2010.205310)
Zitman, F.M.P., Todorov, B., Furukawa, K., Furukawa, K., Willison, H.J. and Plomp, J.J. (2010) Total ganglioside ablation at mouse motor nerve terminals alters neurotransmitter release level. Synapse, 64(4), pp. 335-338. (doi: 10.1002/syn.20747)
Willison, H.J. and Wraith, D.C. (2010) A hazardous vapour trail from abattoir to neuropathy clinic. Lancet Neurology, 9(1), pp. 22-24. (doi: 10.1016/S1474-4422(09)70323-0)
Lockington, D., Imrie, F., Gillen, J., Fitzpatrick, A. and Willison, H. (2010) Visual improvement in established central retinal vein occlusion with long standing macular edema following systemic eculizumab treatment. Canadian Journal of Ophthalmology = Journal canadien d'ophtalmologie, 45(6), p. 649. (doi: 10.3129/i10-060)
Rinaldi, S., Brennan, K.M. and Willison, H.J. (2010) Heteromeric glycolipid complexes as modulators of autoantibody and lectin binding. Progress in Lipid Research, 49(1), pp. 87-95. (doi: 10.1016/j.plipres.2009.09.001)
2009
Jacobs, B.C. and Willison, H.J. (2009) Peripheral neuropathies: biomarkers for axonal damage in immune-mediated neuropathy. Nature Reviews Neurology, 5(11), pp. 584-585. (doi: 10.1038/nrneurol.2009.161)
Reid, J.M., Foley, P. and Willison, H.J. (2009) Voltage-gated potassium channel-associated limbic encephalitis in the west of Scotland: case reports and literature review. Scottish Medical Journal, 54(4), pp. 27-31. (doi: 10.1258/rsmsmj.54.4.27)
Plomp, J.J. and Willison, H.J. (2009) Pathophysiological actions of neuropathy-related anti-ganglioside antibodies at the neuromuscular junction. Journal of Physiology, 587(16), pp. 3979-3999. (doi: 10.1113/jphysiol.2009.171702)
Iorio, R., Capone, F., Iannaccone, E., Willison, H.J. , Modoni, A., Tonali, P.A. and Silvestri, G. (2009) SIADH in a patient with sensory ataxic neuropathy with anti-disialosyl antibodies (CANOMAD). Journal of Neurology, 256(7), pp. 1177-1179. (doi: 10.1007/s00415-009-5071-0)
Greenshields, K.N. et al. (2009) The neuropathic potential of anti-GM1 autoantibodies is regulated by the local glycolipid environment in mice. Journal of Clinical Investigation, 119(3), pp. 595-610. (doi: 10.1172/JCI37338)
Liu, J., Willison, H. and Pedrosa-Domellof, F. (2009) Immunolocalization of GQ1b and Related Gangliosides in Human Extraocular Neuromuscular Junctions and Muscle Spindles. Investigative Ophthalmology and Visual Science, 50(7), pp. 3226-3232.
Lunn, M.P.T. and Willison, H.J. (2009) Diagnosis and treatment in inflammatory neuropathies. Journal of Neurology, Neurosurgery and Psychiatry, 80(3), pp. 249-258.
Lunn, M. and Willison, H. (2009) Diagnosis and treatment in inflammatory neuropathies (Reprinted from Journal of Neurology, Neurosurgery, and Psychiatry, vol 80, pg 249-58, 2009). Postgraduate Medical Journal, 85(1006), pp. 437-446.
Marioni, R. et al. (2009) Peripheral Levels of Fibrinogen, C-Reactive Protein, and Plasma Viscosity Predict Future Cognitive Decline in Individuals Without DementiaPeripheral Neuropathies Biomarkers for Axonal Damage in Immune-Mediated Neuropathy. Psychosomatic Medicine, 71(8), pp. 901-906.
Rinaldi, S., Brennan, K., Goodyear, C. , O'Leary, C., Schiavo, G., Crocker, P. and Willison, H. (2009) Analysis of lectin binding to glycolipid complexes using combinatorial glycoarrays. Glycobiology, 19(7), pp. 789-796. (doi: 10.1093/glycob/cwp049)
Silajdzic, E., Willison, H., Furukawa, K. and Barnett, S. (2009) In Vitro Analysis of Glial Cell Function in Ganglioside-deficient Mice. Journal of Neuroscience Research, 87(11), pp. 2467-2483. (doi: 10.1002/jnr.22085)
2008
Rupp, A., Halstead, S. K. and Willison, H. J. (2008) Age-related Changes to the Distribution of Perisynaptic Schwann Cells at the Murine Neuromuscular Junction. 13th International Congress of the Federation of Societies for Histochemistry and Cytochemistry, Gdansk, Poland, 23-27 Aug 2008.
Halstead, S., Zitman, F., Humphreys, P., Greenshields, K., Verschuuren, J., Jacobs, B., Rother, R., Plomp, J. and Willison, H. (2008) Eculizumab prevents anti-ganglioside antibody-mediated neuropathy in a murine model. Brain, 131(5), pp. 1197-1208. (doi: 10.1093/brain/awm316)
Court, F., Gillingwater, T., Melrose, S., Sherman, D., Greenshields, K., Morton, A., Harris, J., Willison, H. and Ribchester, R. (2008) Identity, developmental restriction and reactivity of extralaminar cells capping mammalian neuromuscular junctions. Journal of Cell Science, 121(23), pp. 3901-3911.
Halstead, S., Humphreys, P., Zitman, F., Hamer, J., Plomp, J. and Willison, H. (2008) C5 inhibitor rEV576 protects against neural injury in an in vitro mouse model of Miller Fisher syndrome. Journal of the Peripheral Nervous System, 13(3), pp. 228-235.
Jacobs, B., Koga, M., van Rijs, W., Geleijns, K., van Doom, P., Willison, H. and Yuki, N. (2008) Subclass IgG to motor gangliosides related to infection and clinical course in Guillain-Barre syndrome. Journal of Neuroimmunology, 194(1-2), pp. 181-190.
Rinaldi, S. and Willison, H. (2008) Ganglioside antibodies and neuropathies. Current Opinion in Neurology, 21(5), pp. 540-546.
Townson, K., Speak, A., Greenshields, K., Goodyear, C. , Willison, H. and Platt, F. (2008) Glycosphingolipid depletion in PC12 cells using iminosugars protects neuronal membranes from anti-ganglioside antibody mediated injury. Journal of Neuroimmunology, 203(1), pp. 33-38. (doi: 10.1016/j.jneuroim.2008.06.033)
Willison, H. , Halstead, S., Bevenidge, E., Zitman, F., Greenshields, K., Morgan, B. and Plomp, J. (2008) The role of complement and complement regulators in mediating motor nerve terminal injury in murine models of Guillain-Barre syndrome. Journal of Neuroimmunology, 201, pp. 172-182.
Willison, H. and Plomp, J. (2008) Anti-ganglioside antibodies and the presynaptic motor nerve terminal. Myasthenia Gravis and Related Disorders, 1132, pp. 114-123.
Zitman, F.M.P., Todorov, B., Jacobs, B.C., Verschuuren, J.J., Furukawa, K., Willison, H.J. and Plomp, J.J. (2008) Neuromuscular synaptic function in mice lacking major subsets of gangliosides. Neuroscience, 156(4), pp. 885-897. (doi: 10.1016/j.neuroscience.2008.08.034)
2007
Willison, H.J. (2007) Gangliosides as targets for autoimmune injury to the nervous system. Journal of Neurochemistry, 103(s1), pp. 143-149. (doi: 10.1111/j.1471-4159.2007.04718.x)
Nachamkin, I. et al. (2007) Patterns of Guillain-Barre syndrome in children - Results from a Mexican population. Neurology, 69, pp. 1665-1671.
Overell, J.R., Hsieh, S.-T., Odaka, M., Yuki, N. and Willison, H.J. (2007) Treatment for Fisher syndrome, Bickerstaff's brainstem encephalitis and related disorders. Cochrane Database of Systematic Reviews(1), CD004761. (doi: 10.1002/14651858.CD004761.pub2)
Townson, K. et al. (2007) Solid phase immunoadsorption for therapeutic and analytical studies on neuropathy-associated anti-GM1 antibodies. Glycobiology, 17, pp. 294-303. (doi: 10.1093/glycob/cwl074)
Townson, K. et al. (2007) Sulfatide binding properties of murine and human antiganglioside antibodies. Glycobiology, 17, pp. 1156-1166. (doi: 10.1093/glycob/cwm095)
2006
Willison, H.J. (2006) Ganglioside complexes as targets for antibodies in Miller Fisher syndrome. Journal of Neurology, Neurosurgery and Psychiatry, 77(9), pp. 1002-1003. (doi: 10.1136/jnnp.2006.094441)
Deinhardt, K., Berninghausen, O., Willison, H.J. , Hopkins, C.R. and Schiavo, G. (2006) Tetanus toxin is internalized by a sequential clathrin-dependent mechanism initiated within lipid microdomains and independent of epsin1. Journal of Cell Biology, 174(3), pp. 459-71. (doi: 10.1083/jcb.200508170)
Avril, T., North, S., Haslam, S., Willison, H. and Crocker, P. (2006) Probing the cis interactions of the inhibitory receptor Siglec-7 with alpha 2,8-disialylated ligands on natural killer cells and other leukocytes using glycan-specific antibodies and by analysis of alpha 2,8-sialyltransferase gene expression. Journal of Leukocyte Biology, 80, pp. 787-796. (doi: 10.1189/jlb.1005559)
Avril, T., Wagner, E., Willison, H. and Crocker, P. (2006) Sialic acid-binding immunoglobulin-like lectin 7 mediates selective recognition of sialylated glycans expressed on Campylobacter jejuni lipooligosaccharides. Infection and Immunity, 74, pp. 4133-4141. (doi: 10.1128/IAI.02094-05)
Willison, H.J. (2006) Basic and clinical aspects of autoimmune disorders in peripheral nerves. Acta Neurologica Scandinavica, 113(s183), pp. 14-18. (doi: 10.1111/j.1600-0404.2006.00607.x)
2005
Halstead, S.K., Morrison, I., O'Hanlon, G.M., Humphreys, P.D., Goodfellow, J.A., Plomp, J.J. and Willison, H.J. (2005) Anti-disialosyl antibodies mediate selective neuronal or Schwann cell injury at mouse neuromuscular junctions. Glia, 52(3), pp. 177-189. (doi: 10.1002/glia.20228)
Willison, H.J. (2005) Ganglioside complexes: new autoantibody targets in Guillain-Barré syndromes. Nature Clinical Practice Neurology, 1(1), pp. 2-3. (doi: 10.1038/ncpneuro0001)
Boffey, J., Odaka, M., Nicoll, D., Wagner, E.R., Townson, K., Bowes, T., Conner, J., Furukawa, K. and Willison, H.J. (2005) Characterisation of the immunoglobulin variable region gene usage encoding the murine anti-ganglioside antibody repertoire. Journal of Neuroimmunology, 165(1-2), pp. 92-103. (doi: 10.1016/j.jneuroim.2005.04.011)
Willison, H.J. (2005) The immunobiology of Guillain-Barré syndromes. Journal of the Peripheral Nervous System, 10(2), pp. 94-112. (doi: 10.1111/j.1085-9489.2005.0010202.x)
Bullens, R., Halstead, S., OHanlon, G., Veitch, J., Molenaar, P., Willison, H. and Plomp, J. (2005) Concanavalin A inhibits pathophysiological effects of anti-ganglioside GQ1b antibodies at the mouse neuromuscular synapse. Muscle and Nerve, 31, pp. 751-760. (doi: 10.1002/mus.20327)
Goodfellow, J. et al. (2005) Overexpression of GD1a ganglioside sensitizes motor nerve terminals to anti-GD1a antibody-mediated injury in a model of acute motor axonal neuropathy. Journal of Neuroscience, 25, pp. 1620-1628. (doi: 10.1523/JNEUROSCI.4279-04.2005)
Halstead, S., Humphreys, P., Goodfellow, J., Wagner, E., Smith, R. and Willison, H. (2005) Complement inhibition abrogates nerve terminal injury in Miller Fisher syndrome. Annals of Neurology, 58, pp. 203-210. (doi: 10.1002/ana.20546)
Overell, J. and Willison, H. (2005) Recent developments in Miller Fisher syndrome and related disorders. Current Opinion in Neurology, 18, pp. 562-566.
2004
Lee, G., Jeong, Y., Wirguin, I., Hays, A.P., Willison, H.J. and Latov, N. (2004) Induction of human IgM and IgG anti-GM1 antibodies in transgenic mice in response to lipopolysaccharides from Campylobacter jejuni. Journal of Neuroimmunology, 146(1-2), pp. 63-75. (doi: 10.1016/j.jneuroim.2003.10.045)
Andersen, S., Ling, C., Zhang, P., Townson, K., Willison, H. and Bundle, D. (2004) Synthesis of ganglioside epitopes for oligosaccharide specific immunoadsorption therapy of Guillian-Barre syndrome. Organic and Biomolecular Chemistry, 2, pp. 1199-1212. (doi: 10.1039/b400029c)
Boffey, J., Nicholl, D., Wagner, E., Townson, K., Goodyear, C., Furukawa, K., Conner, J. and Willison, H. (2004) Innate murine B cells produce anti-disialosyl antibodies reactive with Campylobacter jejuni LPS and gangliosides that are polyreactive and encoded by a restricted set of unmutated V genes. Journal of Neuroimmunology, 152, pp. 98-111. (doi: 10.1016/j.jneuroim.2004.04.002)
Halstead, S., OHanlon, G., Humphreys, P., Morrison, D., Morgan, B., Todd, A., Plomp, J. and Willison, H. (2004) Anti-disialoside antibodies kill perisynaptic Schwann cells and damage motor nerve terminals via membrane attack complex in a murine model of neuropathy. Brain, 127, pp. 2109-2123. (doi: 10.1093/brain/awh231)
Kieseier, B.C., Kiefer, R., Gold, R., Hemmer, B., Willison, H.J. and Hartung, H.P. (2004) Advances in understanding and treatment of immune-mediated disorders of the peripheral nervous system. Muscle and Nerve, 30, pp. 131-156. (doi: 10.1002/mus.20076)
Willison, H., Townson, K., Veitch, J., Boffey, J., Isaacs, N., Andersen, S., Zhang, P., Ling, C. and Bundle, D. (2004) Synthetic disialylgalactose immunoadsorbents deplete anti-GQ1b antibodies from autoimmune nueropathy sera. Brain, 127, pp. 680-691. (doi: 10.1093/brain/awh083)
2003
O'Hanlon, G.M., Hirst, T.R. and Willison, H.J. (2003) Ganglioside GM1 binding toxins and human neuropathy-associated IgM antibodies differentially promote neuritogenesis in a PC12 assay. Neuroscience Research, 47(4), pp. 383-390. (doi: 10.1016/S0168-0102(03)00239-6)
Jacobs, B.C., O'Hanlon, G.M., Bullens, R.W.M., Veitch, J., Plomp, J.J. and Willison, H.J. (2003) Immunoglobulins inhibit pathophysiological effects of anti-GQ1b-positive sera at motor nerve terminals through inhibition of antibody binding. Brain, 126(10), pp. 2220-2234. (doi: 10.1093/brain/awg235)
Bullens, R.W.M., O'Hanlon, G.M., Wagner, E., Molenaar, P.C., Furukawa, K., Furukawa, K., Plomp, J.J. and Willison, H.J. (2003) Roles of complex gangliosides at the neuromuscular junction. Annals of the New York Academy of Sciences, 998(1), pp. 401-403. (doi: 10.1196/annals.1254.051)
Willison, H.J. and Winer, J.B. (2003) Clinical evaluation and investigation of neuropathy. Journal of Neurology, Neurosurgery and Psychiatry, 74(s2), ii3-ii8. (doi: 10.1136/jnnp.74.suppl_2.ii3)
Ooi, M. H. et al. (2003) Adenovirus type 21-associated acute flaccid paralysis during an outbreak of hand-foot-and-mouth disease in Sarawak, Malaysia. Clinical Infectious Diseases, 36(5), pp. 550-559. (doi: 10.1086/367648) (PMID:12594634)
McCrone, P. et al. (2003) Cost-utility analysis of intravenous immunoglobulin and prednisolone for chronic inflammatory demyelinating polyradiculoneuropathy. European Journal of Neurology, 10, pp. 687-694.
OHanlon, G., Humphreys, P., Goldman, R., Halstead, S., Bullens, R., Plomp, J., Ushkaryov, Y. and Willison, H. (2003) Calpain inhibitors protect against axonal degeneration in a model of anti-ganglioside antibody-mediated motor nerve terminal injury. Brain, 126, pp. 2497-2509. (doi: 10.1093/brain/awg254)
Pritchard, J., Gray, I., Idrissova, Z., Lecky, B., Sutton, I., Swan, A., Willison, H. , Winer, J. and Hughes, R. (2003) A randomized controlled trial of recombinant interferon-beta 1a in Guillain-Barre syndrome. Neurology, 61, pp. 1282-1284.
Pritchard, J., Hughes, R.A.C., Rees, J.H., Willison, H.J. and Nicoll, J.A.R. (2003) Apolipoprotein E genotypes and clinical outcome in Guillain-Barre syndrome. Journal of Neurology, Neurosurgery and Psychiatry, 74, pp. 971-973.
Solomon, T. and Willison, H. (2003) Infectious causes of acute flaccid paralysis. Current Opinion in Infectious Diseases, 16, pp. 375-381. (doi: 10.1097/01.qco.0000092807.64370.1e)
2002
Willison, H.J. (2002) Anti-glycolipid antibodies in the diagnosis of autoimmune neuropathies. Revue Neurologique, 158(123), pp. 16-20.
Willison, H.J. and Yuki, N. (2002) Peripheral neuropathies and anti-glycolipid antibodies. Brain, 125(12), pp. 2591-2625. (doi: 10.1093/brain/awf272)
Hartung, H.-P., Willison, H.J. and Kieseier, B.C. (2002) Acute immunoinflammatory neuropathy: update on Guillain-Barré syndrome. Current Opinion in Neurology, 15(5), pp. 571-577.
Bowes, T., Wagner, E.R., Boffey, J., Nicholl, D., Cochrane, L., Benboubetra, M., Conner, J., Furukawa, K., Furukawa, K. and Willison, H.J. (2002) Tolerance to self gangliosides is the major factor restricting the antibody response to lipopolysaccharide core oligosaccharides in Campylobacter jejuni strains associated with Guillain-Barré syndrome. Infection and Immunity, 70(9), pp. 5008-5018. (doi: 10.1128/IAI.70.9.5008-5018.2002)
Bullens, R.W.M., O'Hanlon, G.M., Wagner, E., Molenaar, P.C., Furukawa, K., Furukawa, K., Plomp, J.J. and Willison, H.J. (2002) Complex gangliosides at the neuromuscular junction are membrane receptors for autoantibodies and botulinum neurotoxin but redundant for normal synaptic function. Journal of Neuroscience, 22(16), pp. 6876-6884.
O'Hanlon, G.M., Bullens, R.W.M., Plomp, J.J. and Willison, H.J. (2002) Complex gangliosides as autoantibody targets at the neuromuscular junction in Miller Fisher syndrome: a current perspective. Neurochemical Research, 27(7-8), pp. 697-709. (doi: 10.1023/A:1020284302718)
Jacobs, B.C., Bullens, R.W.M., O'Hanlon, G.M., Ang, C.W., Willison, H.J. and Plomp, J.J. (2002) Detection and prevalence of α-latrotoxin-like effects of serum from patients with Guillain-Barré syndrome. Muscle and Nerve, 25(4), pp. 549-558. (doi: 10.1002/mus.10060)
Ang, C.W., Laman, J.D., Willison, H.J. , Wagner, E.R., Endtz, H.P., De Klerk, M.A., Tio-Gillen, A.P., Van den Braak, N., Jacobs, B.C. and Van Doorn, P.A. (2002) Structure of Campylobacter jejuni lipopolysaccharides determines antiganglioside specificity and clinical features of Guillain-Barré and Miller Fisher patients. Infection and Immunity, 70(3), pp. 1202-1208. (doi: 10.1128/IAI.70.3.1202-1208.2002)
Willison, H.J. , Stoll, G., Toyka, K.V., Berger, T. and Hartung, H.-P. (2002) Autoimmunity and inflammation in the peripheral nervous system. Trends in Neurosciences, 25(3), pp. 127-129. (doi: 10.1016/S0166-2236(00)02120-2)
Comi, G. et al. (2002) A randomised controlled trial of intravenous immunoglobulin in IgM paraprotein associated demyelinating neuropathy. Journal of Neurology, 249, pp. 1370-1377. (doi: 10.1007/s00415-002-0808-z)
2001
Willison, H.J. (2001) Fine specificity of anti-GQ1b antibodies and clinical features. Journal of the Neurological Sciences, 185(1), pp. 1-2. (doi: 10.1016/S0022-510X(01)00465-8)
Serrano-Munuera, C. et al. (2001) Antiganglioside antibodies in acute self-limiting ataxic neuropathy: incidence and significance. Journal of Neuroimmunology, 120(1-2), pp. 78-83. (doi: 10.1016/S0165-5728(01)00428-3)
Hadden, R., Gregson, N., Gold, R., Willison, H. and Hughes, R. (2001) Guillain-Barre syndrome serum and anti-Campylobacter antibody do not exacerbate experimental autoimmune neuritis. Journal of Neuroimmunology, 119, pp. 306-316.
Hughes, R. et al. (2001) Randomized controlled trial of intravenous immunoglobulin versus oral prednisolone in chronic inflammatory demyelinating polyradiculoneuropathy. Annals of Neurology, 50, pp. 195-201.
O'Hanlon, G.M. et al. (2001) Anti-GQ1b ganglioside antibodies mediate complement-dependent destruction of the motor nerve terminal. Brain, 124(5), pp. 893-906. (doi: 10.1093/brain/124.5.893)
Willison, H. et al. (2001) The clinical and laboratory features of chronic sensory ataxic neuropathy with anti-disialosyl IgM antibodies. Brain, 124, pp. 1968-1977.
2000
Willison, H.J. , Ang, W., Gilhus, N.E., Graus, F., Liblau, R., Vedeler, C. and Vincent, A. (2000) EFNS task force report: a questionnaire-based survey on the service provision and quality assurance for determination of diagnostic autoantibody tests in European neuroimmunology centres. European Journal of Neurology, 7(6), pp. 625-628. (doi: 10.1046/j.1468-1331.2000.00158.x)
O'Leary, C.P. and Willison, H.J. (2000) The role of antiglycolipid antibodies in peripheral neuropathies. Current Opinion in Neurology, 13(5), pp. 583-588.
Bensa, S., Hadden, R.D.M., Hahn, A., Hughes, R.A.C. and Willison, H.J. (2000) Randomized controlled trial of brain-derived neurotrophic factor in Guillain-Barré syndrome: a pilot study. European Journal of Neurology, 7(4), pp. 423-426. (doi: 10.1046/j.1468-1331.2000.00096.x)
Bullens, R.W.M., O'Hanlon, G.M., Goodyear, C.S. , Molenaar, P.C., Conner, J., Willison, H.J. and Plomp, J.J. (2000) Anti-GQ1b antibodies and evoked acetylcholine release at mouse motor endplates. Muscle and Nerve, 23(7), pp. 1035-1043. (doi: 10.1002/1097-4598(200007)23:7<1035::AID-MUS5>3.0.CO;2-R)
Lough, J.C., Rafferty, D., McColl, J.H. , Bell, F. and Willison, H.J. (2000) The application of control limits analysis to the myometric assessment of motor performance in neuropathy patients. European Journal of Neurology, 7(4), pp. 427-434. (doi: 10.1046/j.1468-1331.2000.00095.x) (PMID:10971603)
Ponsford, S., Willison, H.J. , Veitch, J., Morris, R. and Thomas, P.K. (2000) Long-term clinical and neurophysiological follow-up of patients with peripheral, neuropathy associated with benign monoclonal gammopathy. Muscle and Nerve, 23(2), pp. 164-174. (doi: 10.1002/(SICI)1097-4598(200002)23:2<164::AID-MUS4>3.0.CO;2-Y)
O'Hanlon, G.M., Veitch, J., Gallardo, E., Illa, I., Chancellor, A.M. and Willison, H.J. (2000) Peripheral neuropathy associated with anti-GM2 ganglioside antibodies: clinical and immunopathological studies. Autoimmunity, 32(2), pp. 133-144.
1999
Willison, H.J. and O'Hanlon, G.M. (1999) The immunopathogenesis of Miller Fisher syndrome. Journal of Neuroimmunology, 100(1-2), pp. 3-12. (doi: 10.1016/S0165-5728(99)00213-1)
Goodyear, C.S. , O'Hanlon, G.M., Plomp, J.J., Wagner, E.R., Cochrane, L., Bullens, R.W.M., Molenaar, P.C., Conner, J. and Willison, H.J. (1999) Monoclonal antibodies raised against Guillain-Barr. Journal of Clinical Investigation, 104(6), pp. 697-708. (doi: 10.1172/JCI6837)
Prendergast, M.M., Willison, H.J. and Moran, A.P. (1999) Human monoclonal immunoglobulin M antibodies to ganglioside GM1 show diverse cross-reactivities with lipopolysaccharides of Campylobacter jejuni strains associated with Guillain-Barré syndrome. Infection and Immunity, 67(7), pp. 3698-3701.
Paparounas, K., O'Hanlon, G.M., O'Leary, C.P., Rowan, E.G. and Willison, H.J. (1999) Anti-ganglioside antibodies can bind peripheral nerve nodes of Ranvier and activate the complement cascade without inducing acute conduction block in vitro. Brain, 122(5), pp. 807-816. (doi: 10.1093/brain/122.5.807)
Ballantyne, J.P. et al. (1999) Management of drug budgets: neurologists do not have confidence in Glasgow's method of managing drugs budget. British Medical Journal, 318(7187), p. 874. (doi: 10.1136/bmj.318.7187.874)
Weiss, M.D., Dalakas, M.C., Lauter, C.J., Willison, H.J. and Quarles, R.H. (1999) Variability in the binding of anti-MAG and anti-SGPG antibodies to target antigens in demyelinating neuropathy and IgM paraproteinemia. Journal of Neuroimmunology, 95(1-2), pp. 174-184. (doi: 10.1016/S0165-5728(98)00247-1)
Ho, T.W. et al. (1999) Anti-GD1a antibody is associated with axonal but not demyelinating forms of Guillain-Barré syndrome. Annals of Neurology, 45(2), pp. 168-173. (doi: 10.1002/1531-8249(199902)45:2<168::AID-ANA6>3.0.CO;2-6)
Benatar, M., Willison, H.J. and Vincent, A. (1999) Immune-mediated peripheral neuropathies and voltage-gated sodiums channels. Muscle and Nerve, 22(1), pp. 108-110. (doi: 10.1002/(SICI)1097-4598(199901)22:1<108::AID-MUS16>3.0.CO;2-I)
Willison, H.J. , Veitch, J., Swan, A.V., Baumann, N., Comi, G., Gregson, N.A., Illa, I., Zielasek, J. and Hughes, R.A.C. (1999) Inter-laboratory validation of an ELISA for the determination of serum anti-ganglioside antibodies. European Journal of Neurology, 6(1), pp. 71-77. (doi: 10.1046/j.1468-1331.1999.610071.x)
1998
Sheikh, K.A. et al. (1998) Campylobacter jejuni lipopolysaccharides in Guillain-Barré syndrome: molecular mimicry and host susceptibility. Neurology, 51(2), pp. 371-378.
O'Hanlon, G.M., Paterson, G.J., Veitch, J., Wilson, G. and Willison, H.J. (1998) Mapping immunoreactive epitopes in the human peripheral nervous system using human monoclonal anti-GM1 ganglioside antibodies. Acta Neuropathologica, 95(6), pp. 605-616.
1997
Benatar, M.G., Willison, H.J. and Vincent, A. (1997) Lack of effect of Miller Fisher sera/plasmas on transmitter release from PC12 cells. Journal of Neuroimmunology, 80(1-2), pp. 1-5. (doi: 10.1016/S0165-5728(97)00127-6)
Jacobs, B.C., O'Hanlon, G.M., Breedland, E.G., Veitch, J., van Doorn, P.A. and Willison, H.J. (1997) Human IgM paraproteins demonstrate shared reactivity between Campylobacter jejuni lipopolysaccharides and human peripheral nerve disialylated gangliosides. Journal of Neuroimmunology, 80(1-2), pp. 23-30. (doi: 10.1016/S0165-5728(97)00130-6)
Willison, H.J. , O'Hanlon, G.M., Paterson, G., O'Leary, C.P., Veitch, J., Wilson, G., Roberts, M., Tang, T. and Vincent, A. (1997) Mechanisms of action of anti-GM1 and anti-GQ1b ganglioside antibodies in Guillain-Barré syndrome. Journal of Infectious Diseases, 176(s2), s144-s149. (doi: 10.1086/513799)
O'Leary, C.P. and Willison, H.J. (1997) Autoimmune ataxic neuropathies (sensory ganglionopathies). Current Opinion in Neurology, 10(5), pp. 366-370.
O'Leary, C.P., Mann, A.C., Lough, J. and Willison, H.J. (1997) Muscle hypertrophy in multifocal motor neuropathy is associated with continuous motor unit activity. Muscle and Nerve, 20(4), pp. 479-485. (doi: 10.1002/(SICI)1097-4598(199704)20:4<479::AID-MUS11>3.0.CO;2-U)
Ho, T.W. et al. (1997) Motor nerve terminal degeneration provides a potential mechanism for rapid recovery in acute motor axonal neuropathy after Campylobacter infection. Neurology, 48(3), pp. 717-724.
1996
Willison, H.J. , O'Hanlon, G.M., Paterson, G., Veitch, J., Wilson, G., Roberts, M., Tang, T. and Vincent, A. (1996) A somatically mutated human antiganglioside IgM antibody that induces experimental neuropathy in mice is encoded by the variable region heavy chain gene, V1-18. Journal of Clinical Investigation, 97(5), pp. 1155-1164.
O'Hanlon, G.M., Paterson, G.J., Wilson, G., Doyle, D., McHardie, P. and Willison, H.J. (1996) Anti-GM1 ganglioside antibodies cloned from autoimmune neuropathy patients show diverse binding patterns in the rodent nervous system. Journal of Neuropathology and Experimental Neurology, 55(2), pp. 184-195.
Jamieson, D.R., Teasdale, E. and Willison, H.J. (1996) False localising signs in the spinal cord. British Medical Journal, 312(7025), pp. 243-244.
Hartung, H.-P., Willison, H.J. , Jung, S., Pette, M., Toyka, K.V. and Giegerich, G. (1996) Autoimmune responses in peripheral nerve. Springer Seminars in Immunopathology, 18(1), pp. 97-123. (doi: 10.1007/BF00792612)
1995
O'Leary, C.P. and Willison, H.J. (1995) Immunological investigation. Current Opinion in Neurology, 8(5), pp. 349-353.
Paterson, G., Wilson, G., Kennedy, P.G. and Willison, H.J. (1995) Analysis of anti-GM1 ganglioside IgM antibodies cloned from motor neuropathy patients demonstrates diverse V region gene usage with extensive somatic mutation. Journal of Immunology, 155(6), pp. 3049-3059.
Roberts, M., Willison, H.J. , Vincent, A. and Newsom-Davis, J. (1995) Multifocal motor neuropathy human sera block distal motor nerve conduction in mice. Annals of Neurology, 38(1), pp. 111-118. (doi: 10.1002/ana.410380118)
Vincent, A., Roberts, M., Willison, H.J. , Lang, B. and Newsom-Davis, J. (1995) Autoantibodies, neurotoxins and the nervous system. Journal of Physiology: Paris, 89(3), pp. 129-136. (doi: 10.1016/0928-4257(96)80110-0)
1994
Willison, H.J. , Almemar, A., Veitch, J. and Thrush, D. (1994) Acute ataxic neuropathy with cross-reactive antibodies to GD1b and GD3 gangliosides. Neurology, 44(12), pp. 2395-2397.
Willison, H.J. (1994) Antiglycolipid antibodies in peripheral neuropathy: fact or fiction? Journal of Neurology, Neurosurgery and Psychiatry, 57(11), pp. 1303-1307. (doi: 10.1136/jnnp.57.11.1303)
Willison, H.J. , Chancellor, A.M., Veitch, J., Kennedy, P.G. and Warlow, C.P. (1994) Immunoglobulin G subclasses are normal in motor neuron disease. Journal of the Neurological Sciences, 124(1), pp. 115-116. (doi: 10.1016/0022-510X(94)90021-3)
Vincent, A., Barrett-Jolley, R., Shillito, P., Hart, I., Beeson, D., MacLennan, C., Nicolle, M., Lang, B., Roberts, M. and Willison, H.J. (1994) Involvement of cation channels in autoimmune disease. Biochemical Society Transactions, 22(2), pp. 488-491.
Thomas, P.K. and Willison, H.J. (1994) Paraproteinaemic neuropathy. Baillière's Clinical Neurology, 3(1), pp. 129-147.
Willison, H.J. , Paterson, G., Kennedy, P.G. and Veitch, J. (1994) Cloning of human anti-GM1 antibodies from motor neuropathy patients. Annals of Neurology, 35(4), pp. 471-478. (doi: 10.1002/ana.410350416)
Willison, H.J. and Veitch, J. (1994) Immunoglobulin subclass distribution and binding characteristics of anti-GQ1b antibodies in Miller Fisher syndrome. Journal of Neuroimmunology, 50(2), pp. 159-165. (doi: 10.1016/0165-5728(94)90042-6)
Roberts, M., Vincent, A., Newsom-Davis, J. and Willison, H.J. (1994) Serum factor in Miller-Fisher variant of Guillain-Barré syndrome and neurotransmitter release. Lancet, 343(8895), pp. 454-5. (doi: 10.1016/S0140-6736(94)92694-8)
de Silva, R.N., Willison, H.J. , Doyle, D., Weir, A.I., Hadley, D.M. and Thomas, A.M. (1994) Nerve root hypertrophy in chronic inflammatory demyelinating polyneuropathy. Muscle and Nerve, 17(2), pp. 168-170. (doi: 10.1002/mus.880170206)
Herron, B., Willison, H.J. , Veitch, J., Roelcke, D., Illis, L.S. and Boulton, F.E. (1994) Monoclonal IgM cold agglutinins with anti-Pr1d specificity in a patient with peripheral neuropathy. Vox Sanguinis, 67(1), pp. 58-63. (doi: 10.1111/j.1423-0410.1994.tb05039.x)
1993
Willison, H.J. , Paterson, G., Veitch, J., Inglis, G. and Barnett, S.C. (1993) Peripheral neuropathy associated with monoclonal IgM anti-Pr2 cold agglutinins. Journal of Neurology, Neurosurgery and Psychiatry, 56(11), pp. 1178-1183. (doi: 10.1136/jnnp.56.11.1178)
Willison, H.J. and Kennedy, P.G. (1993) Gangliosides and bacterial toxins in Guillain-Barré syndrome. Journal of Neuroimmunology, 46(1-2), pp. 105-12. (doi: 10.1016/0165-5728(93)90239-U)
Willison, H.J. and Kennedy, P.G. (1993) The fine specificity of anti-GM1 antibodies. QJM: An International Journal of Medicine, 86(3), pp. 216-217.
Willison, H. J. , Veitch, J., Paterson, G. and Kennedy, P. G. E. (1993) Miller Fisher syndrome is associated with serum antibodies to GQ1b ganglioside. Journal of Neurology, Neurosurgery and Psychiatry, 56(2), pp. 204-206. (doi: 10.1136/jnnp.56.2.204)
Willison, H.J. , Chancellor, A.M., Paterson, G., Veitch, J., Singh, S., Whitelaw, J., Kennedy, P.G. and Warlow, C.P. (1993) Antiglycolipid antibodies, immunoglobulins and paraproteins in motor neuron disease: a population based case-control study. Journal of the Neurological Sciences, 114(2), pp. 209-215. (doi: 10.1016/0022-510X(93)90300-N)
1991
Gregson, N.A., Jones, D., Thomas, P.K. and Willison, H.J. (1991) Acute motor neuropathy with antibodies to GM1 ganglioside. Journal of Neurology, 238(8), pp. 447-451.
Willison, H.J. , Gale, A.N. and McLaughlin, J.E. (1991) Creutzfeldt-Jacob disease following cadaveric dura mater graft. Journal of Neurology, Neurosurgery and Psychiatry, 54(10), p. 940.
1990
Willison, H.J. , Kendall, B.E., Trend, P., Thomas, P.K., Symon, L. and Thrush, D. (1990) Spinal arteriovenous malformation unmasked during intravenous urography. Journal of Neurology, Neurosurgery and Psychiatry, 53(2), pp. 175-176.
Quarles, R.H., Ilyas, A.A. and Willison, H.J. (1990) Antibodies to gangliosides and myelin proteins in Guillain-Barré syndrome. Annals of Neurology, 27(Sup. 1), S48-S52. (doi: 10.1002/ana.410270713)
1988
Willison, H.J. , Trapp, B.D., Bacher, J.D., Dalakas, M.C., Griffin, J.W. and Quarles, R.H. (1988) Demyelination induced by intraneural injection of human antimyelin-associated glycoprotein antibodies. Muscle and Nerve, 11(11), pp. 1169-1176. (doi: 10.1002/mus.880111111)
Ilyas, A.A., Willison, H.J. , Dalakas, M.C., Whitaker, J.N. and Quarles, R.H. (1988) Identification and characterization of gangliosides reacting with IgM paraproteins in three patients with neuropathy associated with biclonal gammopathy. Journal of Neurochemistry, 51(3), pp. 851-858. (doi: 10.1111/j.1471-4159.1988.tb01821.x)
Ilyas, A.A., Willison, H.J. , Quarles, R.H., Jungalwala, F.B., Cornblath, D.R., Trapp, B.D., Griffin, D.E., Griffin, J.W. and McKhann, G.M. (1988) Serum antibodies to gangliosides in Guillain-Barré syndrome. Annals of Neurology, 23(5), pp. 440-447. (doi: 10.1002/ana.410230503)
Willison, H.J. , Trapp, B.D., Bacher, J.D. and Quarles, R.H. (1988) The expression of myelin-associated glycoprotein in regenerating cat sciatic nerve. Brain Research, 444(1), pp. 10-16. (doi: 10.1016/0006-8993(88)90907-9)
1987
Willison, H.J. , Ilyas, A.I., O'Shannessy, D.J., Pulley, M., Trapp, B.D. and Quarles, R.H. (1987) Myelin-associated glycoprotein and related glycoconjugates in developing cat peripheral nerve: a correlative biochemical and morphometric study. Journal of Neurochemistry, 49(6), pp. 1853-1862. (doi: 10.1111/j.1471-4159.1987.tb02447.x)
1986
Quarles, R.H., Ilyas, A.A. and Willison, H.J. (1986) Antibodies to glycolipids in demyelinating diseases of the human peripheral nervous system. Chemistry and Physics of Lipids, 42(1-3), pp. 235-248. (doi: 10.1016/0009-3084(86)90055-1)
Ilyas, A.A., Dobersen, M.J., Willison, H.J. and Quarles, R.H. (1986) Mouse monoclonal and rabbit polyclonal antibodies prepared to human myelin-associated glycoprotein also react with glycosphingolipids of peripheral nerve. Journal of Neuroimmunology, 12(2), pp. 99-106. (doi: 10.1016/0165-5728(86)90023-8)
Willison, H.J. , Minna, J.D., Brady, R.O. and Quarles, R.H. (1986) Glycoconjugates in nervous tissue and small cell lung cancer share immunologically cross-reactive carbohydrate determinants. Journal of Neuroimmunology, 10(4), pp. 353-365. (doi: 10.1016/S0165-5728(86)90018-4)
1985
Willison, H.J. , Muller, D.P., Matthews, S., Jones, S., Kriss, A., Stead, R.J., Hodson, M.E. and Harding, A.E. (1985) A study of the relationship between neurological function and serum vitamin E concentrations in patients with cystic fibrosis. Journal of Neurology, Neurosurgery and Psychiatry, 48(11), pp. 1097-1102.
O'Shannessy, D.J., Willison, H.J. , Inuzuka, T., Dobersen, M.J. and Quarles, R.H. (1985) The species distribution of nervous system antigens that react with anti-myelin-associated glycoprotein antibodies. Journal of Neuroimmunology, 9(5), pp. 255-268. (doi: 10.1016/S0165-5728(85)80024-2)
1982
Harding, A.E., Muller, D.P., Thomas, P.K. and Willison, H.J. (1982) Spinocerebellar degeneration secondary to chronic intestinal malabsorption: a vitamin E deficiency syndrome. Annals of Neurology, 12(5), pp. 419-424.
Articles
Cunningham, M. E. , McGonigal, R. , Barrie, J. A., Campbell, C. I., Yao, D. and Willison, H. J. (2023) Axolemmal nanoruptures arising from paranodal membrane injury induce secondary axon degeneration in murine Guillain-Barré syndrome. Journal of the Peripheral Nervous System, 28(1), pp. 17-31. (doi: 10.1111/jns.12532) (PMID:36710500)
Halstead, S. K. et al. (2023) Serum anti‐GM2 and anti‐GalNAc‐GD1a ganglioside IgG antibodies are biomarkers for immune‐mediated polyneuropathies in cats. Journal of the Peripheral Nervous System, 28(1), pp. 32-40. (doi: 10.1111/jns.12529) (PMID:36573790)
McGonigal, R. , Cunningham, M. E. , Smyth, D., Chou, M., Barrie, J. A., Wilkie, A., Campbell, C., Saatman, K. E., Lunn, M. and Willison, H. J. (2023) The endogenous calpain inhibitor calpastatin attenuates axon degeneration in murine Guillain-Barré syndrome. Journal of the Peripheral Nervous System, 28(1), pp. 4-16. (doi: 10.1111/jns.12520) (PMID:36335586)
McGonigal, R. and Willison, H. J. (2022) The role of gangliosides in the organisation of the node of Ranvier examined in glycosyltransferase transgenic mice. Journal of Anatomy, 241(5), pp. 1259-1271. (doi: 10.1111/joa.13562) (PMID:34605014) (PMCID:PMC9558150)
Cunningham, M. E. , McGonigal, R. , Barrie, J. A., Yao, D. and Willison, H. J. (2022) Real time imaging of intra-axonal calcium flux in an explant mouse model of axonal Guillain-Barré syndrome. Experimental Neurology, 355, 114127. (doi: 10.1016/j.expneurol.2022.114127) (PMID:35640716) (PMCID:PMC7614209)
Leonhard, S. E. et al. (2022) An international perspective on preceding infections in Guillain-Barré syndrome: The IGOS-1000 cohort. Neurology, 99(12), e1299-e1313. (doi: 10.1212/WNL.0000000000200885) (PMID:35981895)
McGonigal, R. , Campbell, C. I., Barrie, J. A., Yao, D., Cunningham, M. E. , Crawford, C. L., Rinaldi, S., Rowan, E. G. and Willison, H. J. (2022) Schwann cell nodal membrane disruption triggers bystander axonal degeneration in a Guillain-Barré syndrome mouse model. Journal of Clinical Investigation, 132(14), e158524. (doi: 10.1172/JCI158524) (PMID:35671105) (PMCID:PMC9282931)
Crawford, C. L. et al. (2022) SARM1 depletion slows axon degeneration in a CNS model of neurotropic viral infection. Frontiers in Molecular Neuroscience, 15, 860410. (doi: 10.3389/fnmol.2022.860410) (PMID:35493328) (PMCID:PMC9043327)
Wilder-Smith, A. et al. (2022) The legacy of ZikaPLAN: a transnational research consortium addressing Zika. Global Health Action, 14(sup1), 2008139. (doi: 10.1080/16549716.2021.2008139) (PMID:35377284) (PMCID:PMC8986226)
Ndondo, A. P., Eley, B., Wilmshurst, J. M., Kakooza-Mwesige, A., Giannoccaro, M. P., Willison, H. J. , Cruz, P. M. R., Heckmann, J. M., Bateman, K. and Vincent, A. (2022) Post-infectious autoimmunity in the central (CNS) and peripheral (PNS) nervous systems: an African perspective. Frontiers in Immunology, 13, 833548. (doi: 10.3389/fimmu.2022.833548) (PMID:35356001) (PMCID:PMC8959857)
Halstead, S.K. et al. (2022) Serum anti-GM2 and anti-GalNAc-GD1a IgG antibodies are biomarkers for acute canine polyradiculoneuritis. Journal of Small Animal Practice, 63(2), pp. 104-112. (doi: 10.1111/jsap.13439) (PMID:34791652)
Campbell, C. I., McGonigal, R. , Barrie, J. A., Delaere, J., Bracke, L., Cunningham, M. E. , Yao, D., Delahaye, T., Van de Walle, I. and Willison, H. J. (2022) Complement inhibition prevents glial nodal membrane injury in a GM1 antibody-mediated mouse model. Brain Communications, 4(6), fcac306. (doi: 10.1093/braincomms/fcac306) (PMID:36523267) (PMCID:PMC9746686)
Persson, B. D., Nord, S., Lindqvist, R., Danskog, K., Överby, A. K., Kohl, A. , Willison, H. J. , Lenman, A. and Arnberg, N. (2021) BAF45b Is required for efficient Zika virus infection of HAP1 cells. Viruses, 13(10), 2007. (doi: 10.3390/v13102007) (PMCID:PMC8540262)
Leonhard, S. E. et al. (2021) Guía basada en la evidencia. Diagnóstico y manejo del síndrome de Guillain-Barré en diez pasos = Evidence based guidelines. Diagnosis and management of Guillain-Barré syndrome in ten steps. Medicina, 81(5), pp. 817-836. (PMID:34633957)
Schultz, V. et al. (2021) Oligodendrocytes are susceptible to Zika virus infection in a mouse model of perinatal exposure: implications for CNS complications. Glia, 69(8), pp. 2023-2036. (doi: 10.1002/glia.24010) (PMID:33942402) (PMCID:PMC9216243)
McGonigal, R. , Barrie, J. A., Yao, D., Black, L. E. , McLaughlin, M. and Willison, H. J. (2021) Neuronally expressed a-series gangliosides are sufficient to prevent the lethal age-dependent phenotype in GM3-only expressing mice. Journal of Neurochemistry, 158(2), pp. 217-232. (doi: 10.1111/jnc.15365) (PMID:33864399)
Schultz, V. et al. (2021) Zika virus infection leads to demyelination and axonal injury in mature CNS cultures. Viruses, 13(1), 91. (doi: 10.3390/v13010091) (PMID:33440758) (PMCID:PMC7827345)
Brito Ferreira, M. L. et al. (2020) Neurological disease in adults with Zika and chikungunya virus infection in Northeast Brazil: a prospective observational study. Lancet Neurology, 19(10), pp. 826-839. (doi: 10.1016/S1474-4422(20)30232-5) (PMID:32949543)
Cunningham, M. E. , Meehan, G. R. , Robinson, S., Yao, D., McGonigal, R. and Willison, H. J. (2020) Perisynaptic Schwann cells phagocytose nerve terminal debris in a mouse model of Guillain-Barré syndrome. Journal of the Peripheral Nervous System, 25(2), pp. 143-151. (doi: 10.1111/jns.12373) (PMID:32250537)
Whitehead, M. J., McCanney, G., Willison, H. J. and Barnett, S. C. (2019) MyelinJ: an ImageJ macro for high throughput analysis of myelinating cultures. Bioinformatics, 35(21), pp. 4528-4530. (doi: 10.1093/bioinformatics/btz403) (PMID:31095292) (PMCID:PMC6821319)
Leonhard, S. E. et al. (2019) Diagnosis and management of Guillain-Barré syndrome in ten steps. Nature Reviews Neurology, 15, pp. 671-683. (doi: 10.1038/s41582-019-0250-9) (PMID:31541214) (PMCID:PMC6821638)
Nutma, E., Willison, H. , Martino, G. and Amor, S. (2019) Neuroimmunology - the past, present and future. Clinical and Experimental Immunology, 197(3), pp. 278-293. (doi: 10.1111/cei.13279) (PMID:30768789) (PMCID:PMC6693969)
Verboon, C. et al. (2019) Current treatment practice of Guillain-Barré syndrome. Neurology, 93(1), e59-e76. (doi: 10.1212/WNL.0000000000007719) (PMID:31175208)
McCanney, G. A., Mcgrath, M. A., Otto, T. D. , Burchmore, R. , Yates, E. A., Bavington, C. D., Willison, H. J. , Turnbull, J. E. and Barnett, S. C. (2019) Low sulfated heparins target multiple proteins for central nervous system repair. Glia, 67(4), pp. 668-687. (doi: 10.1002/glia.23562) (PMID:30585359)
McGonigal, R. , Barrie, J.A., Yao, D., McLaughlin, M. , Cunningham, M.E. , Rowan, E.G. and Willison, H.J. (2019) Glial sulfatides and neuronal complex gangliosides are functionally interdependent in maintaining myelinating axon integrity. Journal of Neuroscience, 39(1), pp. 63-77. (doi: 10.1523/JNEUROSCI.2095-18.2018) (PMID:30446529) (PMCID:PMC6325269)
McCanney, G. A., Lindsay, S. L. , McGrath, M. A., Willison, H. , Moss, C., Bavington, C. and Barnett, S. C. (2019) The use of myelinating cultures as a screen of glycomolecules for CNS repair. Biology, 8(3), 52. (doi: 10.3390/biology8030052) (PMID:31261710)
Wilder-Smith, A. et al. (2019) ZikaPLAN: addressing the knowledge gaps and working towards a research preparedness network in the Americas. Global Health Action, 12(1), 1666566. (doi: 10.1080/16549716.2019.1666566) (PMID:31640505) (PMCID:PMC6818126)
Meehan, G. R. , McGonigal, R. , Cunningham, M. E. , Wang, Y., Barrie, J. A., Halstead, S. K., Gourlay, D., Yao, D. and Willison, H. J. (2018) Differential binding patterns of anti-sulfatide antibodies to glial membranes. Journal of Neuroimmunology, 323, pp. 28-35. (doi: 10.1016/j.jneuroim.2018.07.004) (PMID:30196830) (PMCID:PMC6134133)
Doets, A. Y. et al. (2018) Regional variation of Guillain-Barré syndrome. Brain, 141(10), pp. 2866-2877. (doi: 10.1093/brain/awy232) (PMID:30247567)
Leonhard, S. E., Lant, S., Jacobs, B. C., Wilder-Smith, A., Brito Ferreira, M. L., Solomon, T. and Willison, H. (2018) Zika virus infection in the returning traveller: what every neurologist should know. Practical Neurology, 18(4), pp. 271-277. (doi: 10.1136/practneurol-2017-001789) (PMID:29618586) (PMCID:PMC6204932)
Acosta-Ampudia, Y., Monsalve, D. M., Castillo-Medina, L. F., Rodríguez, Y., Pacheco, Y., Halstead, S., Willison, H. J. , Anaya, J.-M. and Ramírez-Santana, C. (2018) Autoimmune neurological conditions associated with Zika virus infection. Frontiers in Molecular Neuroscience, 11, 116. (doi: 10.3389/fnmol.2018.00116) (PMID:29695953) (PMCID:PMC5904274)
Whitehead, M. J., McGonigal, R. , Willison, H. J. and Barnett, S. C. (2018) Heparanase attenuates axon degeneration following sciatic nerve transection. Scientific Reports, 8, 5219. (doi: 10.1038/s41598-018-23070-6) (PMID:29581478) (PMCID:PMC5980233)
Fehmi, J., Scherer, S. S., Willison, H. J. and Rinaldi, S. (2018) Nodes, paranodes and neuropathies. Journal of Neurology, Neurosurgery and Psychiatry, 89(1), pp. 61-71. (doi: 10.1136/jnnp-2016-315480) (PMID:28819062)
Cumberworth, S. L. et al. (2017) Zika virus tropism and interactions in myelinating neural cell cultures: CNS cells and myelin are preferentially affected. Acta Neuropathologica Communications, 5, 50. (doi: 10.1186/s40478-017-0450-8) (PMID:28645311) (PMCID:PMC5481922)
Jacobs, B. C. et al. (2017) International Guillain-Barré Syndrome Outcome Study (IGOS): protocol of a prospective observational cohort study on clinical and biological predictors of disease course and outcome in Guillain-Barré syndrome. Journal of the Peripheral Nervous System, 22(2), pp. 68-76. (doi: 10.1111/jns.12209) (PMID:28406555)
Kleinecke, S. et al. (2017) Peroxisomal dysfunctions cause lysosomal storage and axonal Kv1 channel redistribution in peripheral neuropathy. eLife, 6, e23332. (doi: 10.7554/elife.23332) (PMID:28470148) (PMCID:PMC5417850)
Clark, A. J., Kaller, M. S., Galino, J., Willison, H. J. , Rinaldi, S. and Bennett, D. L.H. (2017) Co-cultures with stem cell-derived human sensory neurons reveal regulators of peripheral myelination. Brain, 140(4), pp. 898-913. (doi: 10.1093/brain/awx012) (PMID:28334857) (PMCID:PMC5637940)
Davidson, A. I., Halstead, S. K., Goodfellow, J. A., Chavada, G., Mallik, A., Overell, J., Lunn, M. P., McConnachie, A. , van Doorn, P. and Willison, H. J. (2017) Inhibition of complement in Guillain-Barré Syndrome: the ICA-GBS study. Journal of the Peripheral Nervous System, 6, pp. 4-12. (doi: 10.1111/jns.12194) (PMID:27801990)
Wilder-Smith, A. et al. (2017) ZikaPLAN: Zika Preparedness Latin American Network. Global Health Action, 10(1), 1398485. (doi: 10.1080/16549716.2017.1398485) (PMID:29235414)
Goodfellow, J. A. and Willison, H. J. (2016) Guillain-Barré syndrome: a century of progress. Nature Reviews Neurology, 12(12), pp. 723-731. (doi: 10.1038/nrneurol.2016.172) (PMID:27857121)
Halstead, S. K., Kalna, G., Islam, M. B., Jahan, I., Mohammad, Q. D., Jacobs, B. C., Endtz, H. P., Islam, Z. and Willison, H. J. (2016) Microarray screening of Guillain-Barré syndrome sera for antibodies to glycolipid complexes. Neurology: Neuroimmunology and Neuroinflammation, 3(6), e284. (doi: 10.1212/NXI.0000000000000284) (PMID:27790627)
Umapathi, T., Lim, C. S. J., Ooi, E. E., Zhang, S. L., Jin Hui Goh, E., Tan, H. C., Chng, K. Y. S. and Willison, H. (2016) Asymptomatic dengue infection may trigger Guillain-Barré syndrome. Journal of the Peripheral Nervous System, 21(4), pp. 375-377. (doi: 10.1111/jns.12190) (PMID:27717230)
Goodfellow, J. and Willison, H. (2016) Antiganglioside, antiganglioside-complex, and antiglycolipid-complex antibodies in immune-mediated neuropathies. Current Opinion in Neurology, 29(5), pp. 572-580. (doi: 10.1097/WCO.0000000000000361) (PMID:27427992)
Hughes, R. A.C., Cornblath, D. R. and Willison, H. J. (2016) Guillain-Barré syndrome in the 100 years since its description by Guillain, Barré and Strohl. Brain, 139(11), pp. 3041-3047. (doi: 10.1093/brain/aww247) (PMID:29106487)
Willison, H. J. , Jacobs, B. and van Doorn, P. (2016) Guillain-Barré syndrome. Lancet, 388(10045), pp. 717-727. (doi: 10.1016/s0140-6736(16)00339-1) (PMID:26948435)
Cunningham, M. , McGonigal, R. , Meehan, G. R. , Barrie, J. A., Yao, D., Halstead, S. K. and Willison, H. J. (2016) Anti-ganglioside antibodies are removed from circulation in mice by neuronal endocytosis. Brain, 139(6), pp. 1657-1665. (doi: 10.1093/brain/aww056) (PMID:27017187) (PMCID:PMC4892750)
Cao-Lormeau, V.-M. et al. (2016) Guillain-Barré Syndrome outbreak associated with Zika virus infection in French Polynesia: a case-control study. Lancet, 387(10027), pp. 1531-1539. (doi: 10.1016/s0140-6736(16)00562-6) (PMID:26948433) (PMCID:PMC5444521)
Martini, R. and Willison, H. (2016) Neuroinflammation in the peripheral nerve: Cause, modulator, or bystander in peripheral neuropathies? Glia, 64(4), pp. 475-486. (doi: 10.1002/glia.22899) (PMID:26250643) (PMCID:PMC4832258)
McGonigal, R. , Cunningham, M. E. , Yao, D., Barrie, J. A., Sankaranarayanan, S., Fewou, S. N., Furukawa, K., Yednock, T. A. and Willison, H. J. (2016) C1q-targeted inhibition of the classical complement pathway prevents injury in a novel mouse model of acute motor axonal neuropathy. Acta Neuropathologica Communications, 4, 23. (doi: 10.1186/s40478-016-0291-x) (PMID:26936605) (PMCID:PMC4776408)
Feldman, E. L., Hughes, R. A.C. and Willison, H. (2015) Progress in inflammatory neuropathy :the legacy of Dr Jack Griffin. Nature Reviews Neurology, 11(11), pp. 646-650. (doi: 10.1038/nrneurol.2015.192) (PMID:26458287)
Delmont, E., Robb, H., Davidson, A., Halstead, S., Yao, D., Meehan, G. R. and Willison, H. (2015) Prospective study comparing enzyme-linked immunosorbent assay and glycoarray assay to detect antiglycolipid antibodies in a routine diagnostic neuroimmunology laboratory setting. Clinical and Experimental Neuroimmunology, 6(2), pp. 175-182. (doi: 10.1111/cen3.12193)
Delmont, E., Halstead, S., Galban-Horcajo, F., Yao, D., Desnuelle, C. and Willison, H. (2015) Improving the detection of IgM antibodies against glycolipids complexes of GM1 and galactocerebroside in multifocal motor neuropathy using glycoarray and ELISA assays. Journal of Neuroimmunology, 278, pp. 159-161. (doi: 10.1016/j.jneuroim.2014.11.001) (PMID:25468269)
Galban-Horcajo, F., Vlam, L., Delmont, E., Halstead, S. K., van den Berg, L., van der Pol, W.-L. and Willison, H. J. (2015) The diagnostic utility of determining anti-GM1: GalC complex antibodies in multifocal motor neuropathy: a validation study. Journal of Neuromuscular Diseases, 2(2), pp. 157-165. (doi: 10.3233/JND-150080) (PMID:27858734) (PMCID:PMC5271459)
Galban-Horcajo, F., Halstead, S. K., McGonigal, R. and Willison, H. J. (2014) The application of glycosphingolipid arrays to autoantibody detection in neuroimmunological disorders. Current Opinion in Chemical Biology, 18, pp. 78-86. (doi: 10.1016/j.cbpa.2014.01.008)
Fewou, S.N., Plomp, J.J. and Willison, H.J. (2014) The pre-synaptic motor nerve terminal as a site for antibody-mediated neurotoxicity in autoimmune neuropathies and synaptopathies. Journal of Anatomy, 224(1), pp. 36-44. (doi: 10.1111/joa.12088)
Miller, J. A.L., Spyropoulos, A., Jaros, E., Galban-Horcajo, F., Whittaker, R. G. and Willison, H. J. (2014) Anti-GQ1b ganglioside positive Miller Fisher syndrome - evidence of paranodal pathology on nerve biopsy. Journal of Neuromuscular Diseases, 1(2), pp. 191-195. (doi: 10.3233/JND-140039) (PMID:27858774)
Willison, H. J. , Galban-Horcajo, F. and Halstead, S. K. (2014) Antibodies to GM1: galactocerebroside complexes in multifocal motor neuropathy: it takes two to tango. Journal of Neurology, Neurosurgery and Psychiatry, 85(7), p. 715. (doi: 10.1136/jnnp-2013-306050)
Yao, D. et al. (2014) Neuronal expression of galnac transferase is sufficient to prevent the age-related neurodegenerative phenotype of complex ganglioside-deficient mice. Journal of Neuroscience, 34(3), pp. 880-891. (doi: 10.1523/JNEUROSCI.3996-13.2014)
Reindl, M. et al. (2013) Antibodies to heteromeric glycolipid complexes in Guillain-Barré syndrome. PLoS ONE, 8(12), e82337. (doi: 10.1371/journal.pone.0082337) (PMID:24358172) (PMCID:PMC3864991)
Willison, H.J. and Goodyear, C.S. (2013) Glycolipid antigens and autoantibodies in autoimmune neuropathies. Trends in Immunology, 34(9), pp. 453-459. (doi: 10.1016/j.it.2013.05.001)
Rupp, A., Cunningham, M. E. , Yao, D., Furukawa, K. and Willison, H. J. (2013) The effects of age and ganglioside composition on the rate of motor nerve terminal regeneration following antibody-mediated injury in mice. Synapse, 67(7), pp. 382-389. (doi: 10.1002/syn.21648) (PMID:23401234) (PMCID:PMC4495252)
Rupp, A.F., Galban-Horcajo, F., Bianchi, E., Dondi, M., Penderis, J., Cappell, J., Burgess, K., Matiasek, K., McGonigal, R. and Willison, H.J. (2013) Anti-GM2 ganglioside antibodies are a biomarker for acute canine polyradiculoneuritis. Journal of the Peripheral Nervous System, 18(1), pp. 75-88. (doi: 10.1111/jns5.12011) (PMID:23521648)
Galban-Horcajo, F., Fitzpatrick, A.M., Hutton, A.J., Dunn, S.M., Kalna, G., Brennan, K.M., Rinaldi, S., Yu, R.K., Goodyear, C.S. and Willison, H.J. (2013) Antibodies to heteromeric glycolipid complexes in multifocal motor neuropathy. European Journal of Neurology, 20(1), pp. 62-70. (doi: 10.1111/j.1468-1331.2012.03767.x)
Chavada, G. and Willison, H.J. (2012) Autoantibodies in immune-mediated neuropathies. Current Opinion in Neurology, 25(5), pp. 550-555. (doi: 10.1097/WCO.0b013e328357a77f)
Willison, H.J. and Linington, C. (2012) Antibodies to MOG in NMO: a seasoned veteran finds a new role. Neurology, 79(12), pp. 1198-1199. (doi: 10.1212/WNL.0b013e31826aadaf)
Elliott, C. et al. (2012) Functional identification of pathogenic autoantibody responses in patients with multiple sclerosis. Brain, 135(6), pp. 1819-1833. (doi: 10.1093/brain/aws105)
Fewou, S. N., Rupp, A., Nickolay, L. E., Carrick, K., Greenshields, K. N., Pediani, J. , Plomp, J. J. and Willison, H. J. (2012) Anti-ganglioside antibody internalization attenuates motor nerve terminal injury in a mouse model of acute motor axonal neuropathy. Journal of Clinical Investigation, 122(3), pp. 1037-1051. (doi: 10.1172/JCI59110) (PMID:22307327) (PMCID:PMC3287221)
Huizinga, R. et al. (2012) Sialylation of campylobacter jejuni lipo-oligosaccharides: impact on phagocytosis and cytokine production in mice. PLoS ONE, 7(3), e34416. (doi: 10.1371/journal.pone.0034416) (PMID:22470569) (PMCID:PMC3314637)
Islam, Z. et al. (2012) Guillain-Barré Syndrome-related campylobacter jejuni in Bangladesh: ganglioside mimicry and cross-reactive antibodies. PLoS ONE, 7(8), e43976. (doi: 10.1371/journal.pone.0043976) (PMID:22952833) (PMCID:PMC3428305)
Rinaldi, S., Brennan, K.M. and Willison, H.J. (2012) Combinatorial glycoarray. Methods in Molecular Biology, 808, pp. 413-423. (doi: 10.1007/978-1-61779-373-8_28)
Rupp, A., Morrison, I., Barrie, J.A., Halstead, S.K., Townson, K.H., Greenshields, K.N. and Willison, H.J. (2012) Motor nerve terminal destruction and regeneration following anti-ganglioside antibody and complement-mediated injury: An in and ex vivo imaging study in the mouse. Experimental Neurology, 233(2), pp. 836-848. (doi: 10.1016/j.expneurol.2011.12.010)
Höke, A. and Willison, H.J. (2011) In memoriam: remembering John W. 'Jack' Griffin M.D. Nature Reviews Neurology, 7, pp. 361-362. (doi: 10.1038/nrneurol.2011.94)
Barnett, M. H., Barnett, Y., Burke, D. and Willison, H. (2011) Spinal nerve root hypertrophy in chronic ataxic neuropathy with antiglycolipid IgM antibodies. Journal of Neurology, Neurosurgery and Psychiatry, 82(1), p. 97. (doi: 10.1136/jnnp.2010.205096)
Brennan, K.M. et al. (2011) Lipid arrays identify myelin-derived lipids and lipid complexes as prominent targets for oligoclonal band antibodies in multiple sclerosis. Journal of Neuroimmunology, 238(1-2), pp. 87-95. (doi: 10.1016/j.jneuroim.2011.08.002)
Fitzpatrick, A.M., Mann, C.A., Barry, S. , Brennan, K., Overell, J.R. and Willison, H.J. (2011) An open label clinical trial of complement inhibition in multifocal motor neuropathy. Journal of the Peripheral Nervous System, 16(2), pp. 84-91. (doi: 10.1111/j.1529-8027.2011.00328.x)
Hartung, H.-P., Lehmann, H.C. and Willison, H.J. (2011) Peripheral neuropathies: Establishing common clinical research standards for CIDP. Nature Reviews Neurology, 7(5), pp. 250-251. (doi: 10.1038/nrneurol.2011.46)
Nilsson, E.C. et al. (2011) The GD1a glycan is a cellular receptor for adenoviruses causing epidemic keratoconjunctivitis. Nature Medicine, 17(1), pp. 105-109. (doi: 10.1038/nm.2267)
Willison, H. (2011) Reply: Neurofascin as target of autoantibodies in Guillain-Barre syndrome. Brain, 134(5), e174-e174. (doi: 10.1093/brain/awq375)
Willison, H.J. (2011) Biomarkers in experimental models of antibody-mediated neuropathies. Journal of the Peripheral Nervous System, 16, pp. 60-62. (doi: 10.1111/j.1529-8027.2011.00310.x)
Zitman, F.M.P. et al. (2011) Neuropathophysiological potential of Guillain-Barré syndrome anti-ganglioside-complex antibodies at mouse motor nerve terminals. Clinical and Experimental Neuroimmunology, 2(3), pp. 59-67. (doi: 10.1111/j.1759-1961.2011.00022.x)
Zitman, F.M.P., Todorov, B., Verschuuren, J.J., Jacobs, B.C., Furukawa, K., Furukawa, K., Willison, H.J. and Plomp, J.J. (2011) Neuromuscular synaptic transmission in aged ganglioside-deficient mice. Neurobiology of Aging, 32(1), pp. 157-167. (doi: 10.1016/j.neurobiolaging.2009.01.007)
McGonigal, R. , Rowan, E.G., Greenshields, K.N., Halstead, S.K., Humphreys, P.D., Rother, R.P., Furukawa, K. and Willison, H.J. (2010) Anti-GD1a antibodies activate complement and calpain to injure distal motor nodes of Ranvier in mice. Brain, 133(7), pp. 1944-1960. (doi: 10.1093/brain/awq119)
Willison, H.J. (2010) Sugar refining reveals a further specificity for autoantibodies in multifocal motor neuropathy. Journal of Neurology, Neurosurgery and Psychiatry, 81(7), pp. 707-708. (doi: 10.1136/jnnp.2010.205310)
Zitman, F.M.P., Todorov, B., Furukawa, K., Furukawa, K., Willison, H.J. and Plomp, J.J. (2010) Total ganglioside ablation at mouse motor nerve terminals alters neurotransmitter release level. Synapse, 64(4), pp. 335-338. (doi: 10.1002/syn.20747)
Willison, H.J. and Wraith, D.C. (2010) A hazardous vapour trail from abattoir to neuropathy clinic. Lancet Neurology, 9(1), pp. 22-24. (doi: 10.1016/S1474-4422(09)70323-0)
Lockington, D., Imrie, F., Gillen, J., Fitzpatrick, A. and Willison, H. (2010) Visual improvement in established central retinal vein occlusion with long standing macular edema following systemic eculizumab treatment. Canadian Journal of Ophthalmology = Journal canadien d'ophtalmologie, 45(6), p. 649. (doi: 10.3129/i10-060)
Rinaldi, S., Brennan, K.M. and Willison, H.J. (2010) Heteromeric glycolipid complexes as modulators of autoantibody and lectin binding. Progress in Lipid Research, 49(1), pp. 87-95. (doi: 10.1016/j.plipres.2009.09.001)
Jacobs, B.C. and Willison, H.J. (2009) Peripheral neuropathies: biomarkers for axonal damage in immune-mediated neuropathy. Nature Reviews Neurology, 5(11), pp. 584-585. (doi: 10.1038/nrneurol.2009.161)
Reid, J.M., Foley, P. and Willison, H.J. (2009) Voltage-gated potassium channel-associated limbic encephalitis in the west of Scotland: case reports and literature review. Scottish Medical Journal, 54(4), pp. 27-31. (doi: 10.1258/rsmsmj.54.4.27)
Plomp, J.J. and Willison, H.J. (2009) Pathophysiological actions of neuropathy-related anti-ganglioside antibodies at the neuromuscular junction. Journal of Physiology, 587(16), pp. 3979-3999. (doi: 10.1113/jphysiol.2009.171702)
Iorio, R., Capone, F., Iannaccone, E., Willison, H.J. , Modoni, A., Tonali, P.A. and Silvestri, G. (2009) SIADH in a patient with sensory ataxic neuropathy with anti-disialosyl antibodies (CANOMAD). Journal of Neurology, 256(7), pp. 1177-1179. (doi: 10.1007/s00415-009-5071-0)
Greenshields, K.N. et al. (2009) The neuropathic potential of anti-GM1 autoantibodies is regulated by the local glycolipid environment in mice. Journal of Clinical Investigation, 119(3), pp. 595-610. (doi: 10.1172/JCI37338)
Liu, J., Willison, H. and Pedrosa-Domellof, F. (2009) Immunolocalization of GQ1b and Related Gangliosides in Human Extraocular Neuromuscular Junctions and Muscle Spindles. Investigative Ophthalmology and Visual Science, 50(7), pp. 3226-3232.
Lunn, M.P.T. and Willison, H.J. (2009) Diagnosis and treatment in inflammatory neuropathies. Journal of Neurology, Neurosurgery and Psychiatry, 80(3), pp. 249-258.
Lunn, M. and Willison, H. (2009) Diagnosis and treatment in inflammatory neuropathies (Reprinted from Journal of Neurology, Neurosurgery, and Psychiatry, vol 80, pg 249-58, 2009). Postgraduate Medical Journal, 85(1006), pp. 437-446.
Marioni, R. et al. (2009) Peripheral Levels of Fibrinogen, C-Reactive Protein, and Plasma Viscosity Predict Future Cognitive Decline in Individuals Without DementiaPeripheral Neuropathies Biomarkers for Axonal Damage in Immune-Mediated Neuropathy. Psychosomatic Medicine, 71(8), pp. 901-906.
Rinaldi, S., Brennan, K., Goodyear, C. , O'Leary, C., Schiavo, G., Crocker, P. and Willison, H. (2009) Analysis of lectin binding to glycolipid complexes using combinatorial glycoarrays. Glycobiology, 19(7), pp. 789-796. (doi: 10.1093/glycob/cwp049)
Silajdzic, E., Willison, H., Furukawa, K. and Barnett, S. (2009) In Vitro Analysis of Glial Cell Function in Ganglioside-deficient Mice. Journal of Neuroscience Research, 87(11), pp. 2467-2483. (doi: 10.1002/jnr.22085)
Halstead, S., Zitman, F., Humphreys, P., Greenshields, K., Verschuuren, J., Jacobs, B., Rother, R., Plomp, J. and Willison, H. (2008) Eculizumab prevents anti-ganglioside antibody-mediated neuropathy in a murine model. Brain, 131(5), pp. 1197-1208. (doi: 10.1093/brain/awm316)
Court, F., Gillingwater, T., Melrose, S., Sherman, D., Greenshields, K., Morton, A., Harris, J., Willison, H. and Ribchester, R. (2008) Identity, developmental restriction and reactivity of extralaminar cells capping mammalian neuromuscular junctions. Journal of Cell Science, 121(23), pp. 3901-3911.
Halstead, S., Humphreys, P., Zitman, F., Hamer, J., Plomp, J. and Willison, H. (2008) C5 inhibitor rEV576 protects against neural injury in an in vitro mouse model of Miller Fisher syndrome. Journal of the Peripheral Nervous System, 13(3), pp. 228-235.
Jacobs, B., Koga, M., van Rijs, W., Geleijns, K., van Doom, P., Willison, H. and Yuki, N. (2008) Subclass IgG to motor gangliosides related to infection and clinical course in Guillain-Barre syndrome. Journal of Neuroimmunology, 194(1-2), pp. 181-190.
Rinaldi, S. and Willison, H. (2008) Ganglioside antibodies and neuropathies. Current Opinion in Neurology, 21(5), pp. 540-546.
Townson, K., Speak, A., Greenshields, K., Goodyear, C. , Willison, H. and Platt, F. (2008) Glycosphingolipid depletion in PC12 cells using iminosugars protects neuronal membranes from anti-ganglioside antibody mediated injury. Journal of Neuroimmunology, 203(1), pp. 33-38. (doi: 10.1016/j.jneuroim.2008.06.033)
Willison, H. , Halstead, S., Bevenidge, E., Zitman, F., Greenshields, K., Morgan, B. and Plomp, J. (2008) The role of complement and complement regulators in mediating motor nerve terminal injury in murine models of Guillain-Barre syndrome. Journal of Neuroimmunology, 201, pp. 172-182.
Willison, H. and Plomp, J. (2008) Anti-ganglioside antibodies and the presynaptic motor nerve terminal. Myasthenia Gravis and Related Disorders, 1132, pp. 114-123.
Zitman, F.M.P., Todorov, B., Jacobs, B.C., Verschuuren, J.J., Furukawa, K., Willison, H.J. and Plomp, J.J. (2008) Neuromuscular synaptic function in mice lacking major subsets of gangliosides. Neuroscience, 156(4), pp. 885-897. (doi: 10.1016/j.neuroscience.2008.08.034)
Willison, H.J. (2007) Gangliosides as targets for autoimmune injury to the nervous system. Journal of Neurochemistry, 103(s1), pp. 143-149. (doi: 10.1111/j.1471-4159.2007.04718.x)
Nachamkin, I. et al. (2007) Patterns of Guillain-Barre syndrome in children - Results from a Mexican population. Neurology, 69, pp. 1665-1671.
Overell, J.R., Hsieh, S.-T., Odaka, M., Yuki, N. and Willison, H.J. (2007) Treatment for Fisher syndrome, Bickerstaff's brainstem encephalitis and related disorders. Cochrane Database of Systematic Reviews(1), CD004761. (doi: 10.1002/14651858.CD004761.pub2)
Townson, K. et al. (2007) Solid phase immunoadsorption for therapeutic and analytical studies on neuropathy-associated anti-GM1 antibodies. Glycobiology, 17, pp. 294-303. (doi: 10.1093/glycob/cwl074)
Townson, K. et al. (2007) Sulfatide binding properties of murine and human antiganglioside antibodies. Glycobiology, 17, pp. 1156-1166. (doi: 10.1093/glycob/cwm095)
Willison, H.J. (2006) Ganglioside complexes as targets for antibodies in Miller Fisher syndrome. Journal of Neurology, Neurosurgery and Psychiatry, 77(9), pp. 1002-1003. (doi: 10.1136/jnnp.2006.094441)
Deinhardt, K., Berninghausen, O., Willison, H.J. , Hopkins, C.R. and Schiavo, G. (2006) Tetanus toxin is internalized by a sequential clathrin-dependent mechanism initiated within lipid microdomains and independent of epsin1. Journal of Cell Biology, 174(3), pp. 459-71. (doi: 10.1083/jcb.200508170)
Avril, T., North, S., Haslam, S., Willison, H. and Crocker, P. (2006) Probing the cis interactions of the inhibitory receptor Siglec-7 with alpha 2,8-disialylated ligands on natural killer cells and other leukocytes using glycan-specific antibodies and by analysis of alpha 2,8-sialyltransferase gene expression. Journal of Leukocyte Biology, 80, pp. 787-796. (doi: 10.1189/jlb.1005559)
Avril, T., Wagner, E., Willison, H. and Crocker, P. (2006) Sialic acid-binding immunoglobulin-like lectin 7 mediates selective recognition of sialylated glycans expressed on Campylobacter jejuni lipooligosaccharides. Infection and Immunity, 74, pp. 4133-4141. (doi: 10.1128/IAI.02094-05)
Willison, H.J. (2006) Basic and clinical aspects of autoimmune disorders in peripheral nerves. Acta Neurologica Scandinavica, 113(s183), pp. 14-18. (doi: 10.1111/j.1600-0404.2006.00607.x)
Halstead, S.K., Morrison, I., O'Hanlon, G.M., Humphreys, P.D., Goodfellow, J.A., Plomp, J.J. and Willison, H.J. (2005) Anti-disialosyl antibodies mediate selective neuronal or Schwann cell injury at mouse neuromuscular junctions. Glia, 52(3), pp. 177-189. (doi: 10.1002/glia.20228)
Willison, H.J. (2005) Ganglioside complexes: new autoantibody targets in Guillain-Barré syndromes. Nature Clinical Practice Neurology, 1(1), pp. 2-3. (doi: 10.1038/ncpneuro0001)
Boffey, J., Odaka, M., Nicoll, D., Wagner, E.R., Townson, K., Bowes, T., Conner, J., Furukawa, K. and Willison, H.J. (2005) Characterisation of the immunoglobulin variable region gene usage encoding the murine anti-ganglioside antibody repertoire. Journal of Neuroimmunology, 165(1-2), pp. 92-103. (doi: 10.1016/j.jneuroim.2005.04.011)
Willison, H.J. (2005) The immunobiology of Guillain-Barré syndromes. Journal of the Peripheral Nervous System, 10(2), pp. 94-112. (doi: 10.1111/j.1085-9489.2005.0010202.x)
Bullens, R., Halstead, S., OHanlon, G., Veitch, J., Molenaar, P., Willison, H. and Plomp, J. (2005) Concanavalin A inhibits pathophysiological effects of anti-ganglioside GQ1b antibodies at the mouse neuromuscular synapse. Muscle and Nerve, 31, pp. 751-760. (doi: 10.1002/mus.20327)
Goodfellow, J. et al. (2005) Overexpression of GD1a ganglioside sensitizes motor nerve terminals to anti-GD1a antibody-mediated injury in a model of acute motor axonal neuropathy. Journal of Neuroscience, 25, pp. 1620-1628. (doi: 10.1523/JNEUROSCI.4279-04.2005)
Halstead, S., Humphreys, P., Goodfellow, J., Wagner, E., Smith, R. and Willison, H. (2005) Complement inhibition abrogates nerve terminal injury in Miller Fisher syndrome. Annals of Neurology, 58, pp. 203-210. (doi: 10.1002/ana.20546)
Overell, J. and Willison, H. (2005) Recent developments in Miller Fisher syndrome and related disorders. Current Opinion in Neurology, 18, pp. 562-566.
Lee, G., Jeong, Y., Wirguin, I., Hays, A.P., Willison, H.J. and Latov, N. (2004) Induction of human IgM and IgG anti-GM1 antibodies in transgenic mice in response to lipopolysaccharides from Campylobacter jejuni. Journal of Neuroimmunology, 146(1-2), pp. 63-75. (doi: 10.1016/j.jneuroim.2003.10.045)
Andersen, S., Ling, C., Zhang, P., Townson, K., Willison, H. and Bundle, D. (2004) Synthesis of ganglioside epitopes for oligosaccharide specific immunoadsorption therapy of Guillian-Barre syndrome. Organic and Biomolecular Chemistry, 2, pp. 1199-1212. (doi: 10.1039/b400029c)
Boffey, J., Nicholl, D., Wagner, E., Townson, K., Goodyear, C., Furukawa, K., Conner, J. and Willison, H. (2004) Innate murine B cells produce anti-disialosyl antibodies reactive with Campylobacter jejuni LPS and gangliosides that are polyreactive and encoded by a restricted set of unmutated V genes. Journal of Neuroimmunology, 152, pp. 98-111. (doi: 10.1016/j.jneuroim.2004.04.002)
Halstead, S., OHanlon, G., Humphreys, P., Morrison, D., Morgan, B., Todd, A., Plomp, J. and Willison, H. (2004) Anti-disialoside antibodies kill perisynaptic Schwann cells and damage motor nerve terminals via membrane attack complex in a murine model of neuropathy. Brain, 127, pp. 2109-2123. (doi: 10.1093/brain/awh231)
Kieseier, B.C., Kiefer, R., Gold, R., Hemmer, B., Willison, H.J. and Hartung, H.P. (2004) Advances in understanding and treatment of immune-mediated disorders of the peripheral nervous system. Muscle and Nerve, 30, pp. 131-156. (doi: 10.1002/mus.20076)
Willison, H., Townson, K., Veitch, J., Boffey, J., Isaacs, N., Andersen, S., Zhang, P., Ling, C. and Bundle, D. (2004) Synthetic disialylgalactose immunoadsorbents deplete anti-GQ1b antibodies from autoimmune nueropathy sera. Brain, 127, pp. 680-691. (doi: 10.1093/brain/awh083)
O'Hanlon, G.M., Hirst, T.R. and Willison, H.J. (2003) Ganglioside GM1 binding toxins and human neuropathy-associated IgM antibodies differentially promote neuritogenesis in a PC12 assay. Neuroscience Research, 47(4), pp. 383-390. (doi: 10.1016/S0168-0102(03)00239-6)
Jacobs, B.C., O'Hanlon, G.M., Bullens, R.W.M., Veitch, J., Plomp, J.J. and Willison, H.J. (2003) Immunoglobulins inhibit pathophysiological effects of anti-GQ1b-positive sera at motor nerve terminals through inhibition of antibody binding. Brain, 126(10), pp. 2220-2234. (doi: 10.1093/brain/awg235)
Bullens, R.W.M., O'Hanlon, G.M., Wagner, E., Molenaar, P.C., Furukawa, K., Furukawa, K., Plomp, J.J. and Willison, H.J. (2003) Roles of complex gangliosides at the neuromuscular junction. Annals of the New York Academy of Sciences, 998(1), pp. 401-403. (doi: 10.1196/annals.1254.051)
Willison, H.J. and Winer, J.B. (2003) Clinical evaluation and investigation of neuropathy. Journal of Neurology, Neurosurgery and Psychiatry, 74(s2), ii3-ii8. (doi: 10.1136/jnnp.74.suppl_2.ii3)
Ooi, M. H. et al. (2003) Adenovirus type 21-associated acute flaccid paralysis during an outbreak of hand-foot-and-mouth disease in Sarawak, Malaysia. Clinical Infectious Diseases, 36(5), pp. 550-559. (doi: 10.1086/367648) (PMID:12594634)
McCrone, P. et al. (2003) Cost-utility analysis of intravenous immunoglobulin and prednisolone for chronic inflammatory demyelinating polyradiculoneuropathy. European Journal of Neurology, 10, pp. 687-694.
OHanlon, G., Humphreys, P., Goldman, R., Halstead, S., Bullens, R., Plomp, J., Ushkaryov, Y. and Willison, H. (2003) Calpain inhibitors protect against axonal degeneration in a model of anti-ganglioside antibody-mediated motor nerve terminal injury. Brain, 126, pp. 2497-2509. (doi: 10.1093/brain/awg254)
Pritchard, J., Gray, I., Idrissova, Z., Lecky, B., Sutton, I., Swan, A., Willison, H. , Winer, J. and Hughes, R. (2003) A randomized controlled trial of recombinant interferon-beta 1a in Guillain-Barre syndrome. Neurology, 61, pp. 1282-1284.
Pritchard, J., Hughes, R.A.C., Rees, J.H., Willison, H.J. and Nicoll, J.A.R. (2003) Apolipoprotein E genotypes and clinical outcome in Guillain-Barre syndrome. Journal of Neurology, Neurosurgery and Psychiatry, 74, pp. 971-973.
Solomon, T. and Willison, H. (2003) Infectious causes of acute flaccid paralysis. Current Opinion in Infectious Diseases, 16, pp. 375-381. (doi: 10.1097/01.qco.0000092807.64370.1e)
Willison, H.J. (2002) Anti-glycolipid antibodies in the diagnosis of autoimmune neuropathies. Revue Neurologique, 158(123), pp. 16-20.
Willison, H.J. and Yuki, N. (2002) Peripheral neuropathies and anti-glycolipid antibodies. Brain, 125(12), pp. 2591-2625. (doi: 10.1093/brain/awf272)
Hartung, H.-P., Willison, H.J. and Kieseier, B.C. (2002) Acute immunoinflammatory neuropathy: update on Guillain-Barré syndrome. Current Opinion in Neurology, 15(5), pp. 571-577.
Bowes, T., Wagner, E.R., Boffey, J., Nicholl, D., Cochrane, L., Benboubetra, M., Conner, J., Furukawa, K., Furukawa, K. and Willison, H.J. (2002) Tolerance to self gangliosides is the major factor restricting the antibody response to lipopolysaccharide core oligosaccharides in Campylobacter jejuni strains associated with Guillain-Barré syndrome. Infection and Immunity, 70(9), pp. 5008-5018. (doi: 10.1128/IAI.70.9.5008-5018.2002)
Bullens, R.W.M., O'Hanlon, G.M., Wagner, E., Molenaar, P.C., Furukawa, K., Furukawa, K., Plomp, J.J. and Willison, H.J. (2002) Complex gangliosides at the neuromuscular junction are membrane receptors for autoantibodies and botulinum neurotoxin but redundant for normal synaptic function. Journal of Neuroscience, 22(16), pp. 6876-6884.
O'Hanlon, G.M., Bullens, R.W.M., Plomp, J.J. and Willison, H.J. (2002) Complex gangliosides as autoantibody targets at the neuromuscular junction in Miller Fisher syndrome: a current perspective. Neurochemical Research, 27(7-8), pp. 697-709. (doi: 10.1023/A:1020284302718)
Jacobs, B.C., Bullens, R.W.M., O'Hanlon, G.M., Ang, C.W., Willison, H.J. and Plomp, J.J. (2002) Detection and prevalence of α-latrotoxin-like effects of serum from patients with Guillain-Barré syndrome. Muscle and Nerve, 25(4), pp. 549-558. (doi: 10.1002/mus.10060)
Ang, C.W., Laman, J.D., Willison, H.J. , Wagner, E.R., Endtz, H.P., De Klerk, M.A., Tio-Gillen, A.P., Van den Braak, N., Jacobs, B.C. and Van Doorn, P.A. (2002) Structure of Campylobacter jejuni lipopolysaccharides determines antiganglioside specificity and clinical features of Guillain-Barré and Miller Fisher patients. Infection and Immunity, 70(3), pp. 1202-1208. (doi: 10.1128/IAI.70.3.1202-1208.2002)
Willison, H.J. , Stoll, G., Toyka, K.V., Berger, T. and Hartung, H.-P. (2002) Autoimmunity and inflammation in the peripheral nervous system. Trends in Neurosciences, 25(3), pp. 127-129. (doi: 10.1016/S0166-2236(00)02120-2)
Comi, G. et al. (2002) A randomised controlled trial of intravenous immunoglobulin in IgM paraprotein associated demyelinating neuropathy. Journal of Neurology, 249, pp. 1370-1377. (doi: 10.1007/s00415-002-0808-z)
Willison, H.J. (2001) Fine specificity of anti-GQ1b antibodies and clinical features. Journal of the Neurological Sciences, 185(1), pp. 1-2. (doi: 10.1016/S0022-510X(01)00465-8)
Serrano-Munuera, C. et al. (2001) Antiganglioside antibodies in acute self-limiting ataxic neuropathy: incidence and significance. Journal of Neuroimmunology, 120(1-2), pp. 78-83. (doi: 10.1016/S0165-5728(01)00428-3)
Hadden, R., Gregson, N., Gold, R., Willison, H. and Hughes, R. (2001) Guillain-Barre syndrome serum and anti-Campylobacter antibody do not exacerbate experimental autoimmune neuritis. Journal of Neuroimmunology, 119, pp. 306-316.
Hughes, R. et al. (2001) Randomized controlled trial of intravenous immunoglobulin versus oral prednisolone in chronic inflammatory demyelinating polyradiculoneuropathy. Annals of Neurology, 50, pp. 195-201.
O'Hanlon, G.M. et al. (2001) Anti-GQ1b ganglioside antibodies mediate complement-dependent destruction of the motor nerve terminal. Brain, 124(5), pp. 893-906. (doi: 10.1093/brain/124.5.893)
Willison, H. et al. (2001) The clinical and laboratory features of chronic sensory ataxic neuropathy with anti-disialosyl IgM antibodies. Brain, 124, pp. 1968-1977.
Willison, H.J. , Ang, W., Gilhus, N.E., Graus, F., Liblau, R., Vedeler, C. and Vincent, A. (2000) EFNS task force report: a questionnaire-based survey on the service provision and quality assurance for determination of diagnostic autoantibody tests in European neuroimmunology centres. European Journal of Neurology, 7(6), pp. 625-628. (doi: 10.1046/j.1468-1331.2000.00158.x)
O'Leary, C.P. and Willison, H.J. (2000) The role of antiglycolipid antibodies in peripheral neuropathies. Current Opinion in Neurology, 13(5), pp. 583-588.
Bensa, S., Hadden, R.D.M., Hahn, A., Hughes, R.A.C. and Willison, H.J. (2000) Randomized controlled trial of brain-derived neurotrophic factor in Guillain-Barré syndrome: a pilot study. European Journal of Neurology, 7(4), pp. 423-426. (doi: 10.1046/j.1468-1331.2000.00096.x)
Bullens, R.W.M., O'Hanlon, G.M., Goodyear, C.S. , Molenaar, P.C., Conner, J., Willison, H.J. and Plomp, J.J. (2000) Anti-GQ1b antibodies and evoked acetylcholine release at mouse motor endplates. Muscle and Nerve, 23(7), pp. 1035-1043. (doi: 10.1002/1097-4598(200007)23:7<1035::AID-MUS5>3.0.CO;2-R)
Lough, J.C., Rafferty, D., McColl, J.H. , Bell, F. and Willison, H.J. (2000) The application of control limits analysis to the myometric assessment of motor performance in neuropathy patients. European Journal of Neurology, 7(4), pp. 427-434. (doi: 10.1046/j.1468-1331.2000.00095.x) (PMID:10971603)
Ponsford, S., Willison, H.J. , Veitch, J., Morris, R. and Thomas, P.K. (2000) Long-term clinical and neurophysiological follow-up of patients with peripheral, neuropathy associated with benign monoclonal gammopathy. Muscle and Nerve, 23(2), pp. 164-174. (doi: 10.1002/(SICI)1097-4598(200002)23:2<164::AID-MUS4>3.0.CO;2-Y)
O'Hanlon, G.M., Veitch, J., Gallardo, E., Illa, I., Chancellor, A.M. and Willison, H.J. (2000) Peripheral neuropathy associated with anti-GM2 ganglioside antibodies: clinical and immunopathological studies. Autoimmunity, 32(2), pp. 133-144.
Willison, H.J. and O'Hanlon, G.M. (1999) The immunopathogenesis of Miller Fisher syndrome. Journal of Neuroimmunology, 100(1-2), pp. 3-12. (doi: 10.1016/S0165-5728(99)00213-1)
Goodyear, C.S. , O'Hanlon, G.M., Plomp, J.J., Wagner, E.R., Cochrane, L., Bullens, R.W.M., Molenaar, P.C., Conner, J. and Willison, H.J. (1999) Monoclonal antibodies raised against Guillain-Barr. Journal of Clinical Investigation, 104(6), pp. 697-708. (doi: 10.1172/JCI6837)
Prendergast, M.M., Willison, H.J. and Moran, A.P. (1999) Human monoclonal immunoglobulin M antibodies to ganglioside GM1 show diverse cross-reactivities with lipopolysaccharides of Campylobacter jejuni strains associated with Guillain-Barré syndrome. Infection and Immunity, 67(7), pp. 3698-3701.
Paparounas, K., O'Hanlon, G.M., O'Leary, C.P., Rowan, E.G. and Willison, H.J. (1999) Anti-ganglioside antibodies can bind peripheral nerve nodes of Ranvier and activate the complement cascade without inducing acute conduction block in vitro. Brain, 122(5), pp. 807-816. (doi: 10.1093/brain/122.5.807)
Ballantyne, J.P. et al. (1999) Management of drug budgets: neurologists do not have confidence in Glasgow's method of managing drugs budget. British Medical Journal, 318(7187), p. 874. (doi: 10.1136/bmj.318.7187.874)
Weiss, M.D., Dalakas, M.C., Lauter, C.J., Willison, H.J. and Quarles, R.H. (1999) Variability in the binding of anti-MAG and anti-SGPG antibodies to target antigens in demyelinating neuropathy and IgM paraproteinemia. Journal of Neuroimmunology, 95(1-2), pp. 174-184. (doi: 10.1016/S0165-5728(98)00247-1)
Ho, T.W. et al. (1999) Anti-GD1a antibody is associated with axonal but not demyelinating forms of Guillain-Barré syndrome. Annals of Neurology, 45(2), pp. 168-173. (doi: 10.1002/1531-8249(199902)45:2<168::AID-ANA6>3.0.CO;2-6)
Benatar, M., Willison, H.J. and Vincent, A. (1999) Immune-mediated peripheral neuropathies and voltage-gated sodiums channels. Muscle and Nerve, 22(1), pp. 108-110. (doi: 10.1002/(SICI)1097-4598(199901)22:1<108::AID-MUS16>3.0.CO;2-I)
Willison, H.J. , Veitch, J., Swan, A.V., Baumann, N., Comi, G., Gregson, N.A., Illa, I., Zielasek, J. and Hughes, R.A.C. (1999) Inter-laboratory validation of an ELISA for the determination of serum anti-ganglioside antibodies. European Journal of Neurology, 6(1), pp. 71-77. (doi: 10.1046/j.1468-1331.1999.610071.x)
Sheikh, K.A. et al. (1998) Campylobacter jejuni lipopolysaccharides in Guillain-Barré syndrome: molecular mimicry and host susceptibility. Neurology, 51(2), pp. 371-378.
O'Hanlon, G.M., Paterson, G.J., Veitch, J., Wilson, G. and Willison, H.J. (1998) Mapping immunoreactive epitopes in the human peripheral nervous system using human monoclonal anti-GM1 ganglioside antibodies. Acta Neuropathologica, 95(6), pp. 605-616.
Benatar, M.G., Willison, H.J. and Vincent, A. (1997) Lack of effect of Miller Fisher sera/plasmas on transmitter release from PC12 cells. Journal of Neuroimmunology, 80(1-2), pp. 1-5. (doi: 10.1016/S0165-5728(97)00127-6)
Jacobs, B.C., O'Hanlon, G.M., Breedland, E.G., Veitch, J., van Doorn, P.A. and Willison, H.J. (1997) Human IgM paraproteins demonstrate shared reactivity between Campylobacter jejuni lipopolysaccharides and human peripheral nerve disialylated gangliosides. Journal of Neuroimmunology, 80(1-2), pp. 23-30. (doi: 10.1016/S0165-5728(97)00130-6)
Willison, H.J. , O'Hanlon, G.M., Paterson, G., O'Leary, C.P., Veitch, J., Wilson, G., Roberts, M., Tang, T. and Vincent, A. (1997) Mechanisms of action of anti-GM1 and anti-GQ1b ganglioside antibodies in Guillain-Barré syndrome. Journal of Infectious Diseases, 176(s2), s144-s149. (doi: 10.1086/513799)
O'Leary, C.P. and Willison, H.J. (1997) Autoimmune ataxic neuropathies (sensory ganglionopathies). Current Opinion in Neurology, 10(5), pp. 366-370.
O'Leary, C.P., Mann, A.C., Lough, J. and Willison, H.J. (1997) Muscle hypertrophy in multifocal motor neuropathy is associated with continuous motor unit activity. Muscle and Nerve, 20(4), pp. 479-485. (doi: 10.1002/(SICI)1097-4598(199704)20:4<479::AID-MUS11>3.0.CO;2-U)
Ho, T.W. et al. (1997) Motor nerve terminal degeneration provides a potential mechanism for rapid recovery in acute motor axonal neuropathy after Campylobacter infection. Neurology, 48(3), pp. 717-724.
Willison, H.J. , O'Hanlon, G.M., Paterson, G., Veitch, J., Wilson, G., Roberts, M., Tang, T. and Vincent, A. (1996) A somatically mutated human antiganglioside IgM antibody that induces experimental neuropathy in mice is encoded by the variable region heavy chain gene, V1-18. Journal of Clinical Investigation, 97(5), pp. 1155-1164.
O'Hanlon, G.M., Paterson, G.J., Wilson, G., Doyle, D., McHardie, P. and Willison, H.J. (1996) Anti-GM1 ganglioside antibodies cloned from autoimmune neuropathy patients show diverse binding patterns in the rodent nervous system. Journal of Neuropathology and Experimental Neurology, 55(2), pp. 184-195.
Jamieson, D.R., Teasdale, E. and Willison, H.J. (1996) False localising signs in the spinal cord. British Medical Journal, 312(7025), pp. 243-244.
Hartung, H.-P., Willison, H.J. , Jung, S., Pette, M., Toyka, K.V. and Giegerich, G. (1996) Autoimmune responses in peripheral nerve. Springer Seminars in Immunopathology, 18(1), pp. 97-123. (doi: 10.1007/BF00792612)
O'Leary, C.P. and Willison, H.J. (1995) Immunological investigation. Current Opinion in Neurology, 8(5), pp. 349-353.
Paterson, G., Wilson, G., Kennedy, P.G. and Willison, H.J. (1995) Analysis of anti-GM1 ganglioside IgM antibodies cloned from motor neuropathy patients demonstrates diverse V region gene usage with extensive somatic mutation. Journal of Immunology, 155(6), pp. 3049-3059.
Roberts, M., Willison, H.J. , Vincent, A. and Newsom-Davis, J. (1995) Multifocal motor neuropathy human sera block distal motor nerve conduction in mice. Annals of Neurology, 38(1), pp. 111-118. (doi: 10.1002/ana.410380118)
Vincent, A., Roberts, M., Willison, H.J. , Lang, B. and Newsom-Davis, J. (1995) Autoantibodies, neurotoxins and the nervous system. Journal of Physiology: Paris, 89(3), pp. 129-136. (doi: 10.1016/0928-4257(96)80110-0)
Willison, H.J. , Almemar, A., Veitch, J. and Thrush, D. (1994) Acute ataxic neuropathy with cross-reactive antibodies to GD1b and GD3 gangliosides. Neurology, 44(12), pp. 2395-2397.
Willison, H.J. (1994) Antiglycolipid antibodies in peripheral neuropathy: fact or fiction? Journal of Neurology, Neurosurgery and Psychiatry, 57(11), pp. 1303-1307. (doi: 10.1136/jnnp.57.11.1303)
Willison, H.J. , Chancellor, A.M., Veitch, J., Kennedy, P.G. and Warlow, C.P. (1994) Immunoglobulin G subclasses are normal in motor neuron disease. Journal of the Neurological Sciences, 124(1), pp. 115-116. (doi: 10.1016/0022-510X(94)90021-3)
Vincent, A., Barrett-Jolley, R., Shillito, P., Hart, I., Beeson, D., MacLennan, C., Nicolle, M., Lang, B., Roberts, M. and Willison, H.J. (1994) Involvement of cation channels in autoimmune disease. Biochemical Society Transactions, 22(2), pp. 488-491.
Thomas, P.K. and Willison, H.J. (1994) Paraproteinaemic neuropathy. Baillière's Clinical Neurology, 3(1), pp. 129-147.
Willison, H.J. , Paterson, G., Kennedy, P.G. and Veitch, J. (1994) Cloning of human anti-GM1 antibodies from motor neuropathy patients. Annals of Neurology, 35(4), pp. 471-478. (doi: 10.1002/ana.410350416)
Willison, H.J. and Veitch, J. (1994) Immunoglobulin subclass distribution and binding characteristics of anti-GQ1b antibodies in Miller Fisher syndrome. Journal of Neuroimmunology, 50(2), pp. 159-165. (doi: 10.1016/0165-5728(94)90042-6)
Roberts, M., Vincent, A., Newsom-Davis, J. and Willison, H.J. (1994) Serum factor in Miller-Fisher variant of Guillain-Barré syndrome and neurotransmitter release. Lancet, 343(8895), pp. 454-5. (doi: 10.1016/S0140-6736(94)92694-8)
de Silva, R.N., Willison, H.J. , Doyle, D., Weir, A.I., Hadley, D.M. and Thomas, A.M. (1994) Nerve root hypertrophy in chronic inflammatory demyelinating polyneuropathy. Muscle and Nerve, 17(2), pp. 168-170. (doi: 10.1002/mus.880170206)
Herron, B., Willison, H.J. , Veitch, J., Roelcke, D., Illis, L.S. and Boulton, F.E. (1994) Monoclonal IgM cold agglutinins with anti-Pr1d specificity in a patient with peripheral neuropathy. Vox Sanguinis, 67(1), pp. 58-63. (doi: 10.1111/j.1423-0410.1994.tb05039.x)
Willison, H.J. , Paterson, G., Veitch, J., Inglis, G. and Barnett, S.C. (1993) Peripheral neuropathy associated with monoclonal IgM anti-Pr2 cold agglutinins. Journal of Neurology, Neurosurgery and Psychiatry, 56(11), pp. 1178-1183. (doi: 10.1136/jnnp.56.11.1178)
Willison, H.J. and Kennedy, P.G. (1993) Gangliosides and bacterial toxins in Guillain-Barré syndrome. Journal of Neuroimmunology, 46(1-2), pp. 105-12. (doi: 10.1016/0165-5728(93)90239-U)
Willison, H.J. and Kennedy, P.G. (1993) The fine specificity of anti-GM1 antibodies. QJM: An International Journal of Medicine, 86(3), pp. 216-217.
Willison, H. J. , Veitch, J., Paterson, G. and Kennedy, P. G. E. (1993) Miller Fisher syndrome is associated with serum antibodies to GQ1b ganglioside. Journal of Neurology, Neurosurgery and Psychiatry, 56(2), pp. 204-206. (doi: 10.1136/jnnp.56.2.204)
Willison, H.J. , Chancellor, A.M., Paterson, G., Veitch, J., Singh, S., Whitelaw, J., Kennedy, P.G. and Warlow, C.P. (1993) Antiglycolipid antibodies, immunoglobulins and paraproteins in motor neuron disease: a population based case-control study. Journal of the Neurological Sciences, 114(2), pp. 209-215. (doi: 10.1016/0022-510X(93)90300-N)
Gregson, N.A., Jones, D., Thomas, P.K. and Willison, H.J. (1991) Acute motor neuropathy with antibodies to GM1 ganglioside. Journal of Neurology, 238(8), pp. 447-451.
Willison, H.J. , Gale, A.N. and McLaughlin, J.E. (1991) Creutzfeldt-Jacob disease following cadaveric dura mater graft. Journal of Neurology, Neurosurgery and Psychiatry, 54(10), p. 940.
Willison, H.J. , Kendall, B.E., Trend, P., Thomas, P.K., Symon, L. and Thrush, D. (1990) Spinal arteriovenous malformation unmasked during intravenous urography. Journal of Neurology, Neurosurgery and Psychiatry, 53(2), pp. 175-176.
Quarles, R.H., Ilyas, A.A. and Willison, H.J. (1990) Antibodies to gangliosides and myelin proteins in Guillain-Barré syndrome. Annals of Neurology, 27(Sup. 1), S48-S52. (doi: 10.1002/ana.410270713)
Willison, H.J. , Trapp, B.D., Bacher, J.D., Dalakas, M.C., Griffin, J.W. and Quarles, R.H. (1988) Demyelination induced by intraneural injection of human antimyelin-associated glycoprotein antibodies. Muscle and Nerve, 11(11), pp. 1169-1176. (doi: 10.1002/mus.880111111)
Ilyas, A.A., Willison, H.J. , Dalakas, M.C., Whitaker, J.N. and Quarles, R.H. (1988) Identification and characterization of gangliosides reacting with IgM paraproteins in three patients with neuropathy associated with biclonal gammopathy. Journal of Neurochemistry, 51(3), pp. 851-858. (doi: 10.1111/j.1471-4159.1988.tb01821.x)
Ilyas, A.A., Willison, H.J. , Quarles, R.H., Jungalwala, F.B., Cornblath, D.R., Trapp, B.D., Griffin, D.E., Griffin, J.W. and McKhann, G.M. (1988) Serum antibodies to gangliosides in Guillain-Barré syndrome. Annals of Neurology, 23(5), pp. 440-447. (doi: 10.1002/ana.410230503)
Willison, H.J. , Trapp, B.D., Bacher, J.D. and Quarles, R.H. (1988) The expression of myelin-associated glycoprotein in regenerating cat sciatic nerve. Brain Research, 444(1), pp. 10-16. (doi: 10.1016/0006-8993(88)90907-9)
Willison, H.J. , Ilyas, A.I., O'Shannessy, D.J., Pulley, M., Trapp, B.D. and Quarles, R.H. (1987) Myelin-associated glycoprotein and related glycoconjugates in developing cat peripheral nerve: a correlative biochemical and morphometric study. Journal of Neurochemistry, 49(6), pp. 1853-1862. (doi: 10.1111/j.1471-4159.1987.tb02447.x)
Quarles, R.H., Ilyas, A.A. and Willison, H.J. (1986) Antibodies to glycolipids in demyelinating diseases of the human peripheral nervous system. Chemistry and Physics of Lipids, 42(1-3), pp. 235-248. (doi: 10.1016/0009-3084(86)90055-1)
Ilyas, A.A., Dobersen, M.J., Willison, H.J. and Quarles, R.H. (1986) Mouse monoclonal and rabbit polyclonal antibodies prepared to human myelin-associated glycoprotein also react with glycosphingolipids of peripheral nerve. Journal of Neuroimmunology, 12(2), pp. 99-106. (doi: 10.1016/0165-5728(86)90023-8)
Willison, H.J. , Minna, J.D., Brady, R.O. and Quarles, R.H. (1986) Glycoconjugates in nervous tissue and small cell lung cancer share immunologically cross-reactive carbohydrate determinants. Journal of Neuroimmunology, 10(4), pp. 353-365. (doi: 10.1016/S0165-5728(86)90018-4)
Willison, H.J. , Muller, D.P., Matthews, S., Jones, S., Kriss, A., Stead, R.J., Hodson, M.E. and Harding, A.E. (1985) A study of the relationship between neurological function and serum vitamin E concentrations in patients with cystic fibrosis. Journal of Neurology, Neurosurgery and Psychiatry, 48(11), pp. 1097-1102.
O'Shannessy, D.J., Willison, H.J. , Inuzuka, T., Dobersen, M.J. and Quarles, R.H. (1985) The species distribution of nervous system antigens that react with anti-myelin-associated glycoprotein antibodies. Journal of Neuroimmunology, 9(5), pp. 255-268. (doi: 10.1016/S0165-5728(85)80024-2)
Harding, A.E., Muller, D.P., Thomas, P.K. and Willison, H.J. (1982) Spinocerebellar degeneration secondary to chronic intestinal malabsorption: a vitamin E deficiency syndrome. Annals of Neurology, 12(5), pp. 419-424.
Book Sections
Halstead, S. K., Gourlay, D. and Willison, H. J. (2022) Detection of autoantibodies using combinatorial glycolipid microarrays. In: Kilcoyne, M. and Gerlach, J. Q. (eds.) Glycan Microarrays: Methods and Protocols. Series: Methods in Molecular Biology, 2460. Humana Press: New York, pp. 183-191. ISBN 9781071621479 (doi: 10.1007/978-1-0716-2148-6_11)
Goodfellow, J. A. and Willison, H. J. (2018) Gangliosides and autoimmune peripheral nerve diseases. In: Gangliosides in Health and Disease. Series: Progress in Molecular Biology and Translational Science, 156. Elsevier, pp. 355-382. ISBN 9780128123416 (doi: 10.1016/bs.pmbts.2017.12.010)
Willison, H. J. (2018) Anti-ganglioside antibodies in peripheral nerve pathology. In: Sonnino, S. and Prinetti, A. (eds.) Gangliosides: Methods and Protocols. Series: Methods in molecular biology (1804). Humana Press: New York, NY, pp. 173-188. ISBN 9781493985517 (doi: 10.1007/978-1-4939-8552-4_7)
Edited Books
Willison, H. J. and Goodfellow, J. A. (Eds.) (2016) GBS100: Celebrating a Century of Progress in Guillain-Barré Syndrome. Peripheral Nerve Society: San Diego, CA. ISBN 9780997510300
Conference or Workshop Item
Rupp, A. et al. (2017) The Sero-Prevalence of Anti-Glycolipid Antibodies in Acute Canine Polyradiculoneuritis and Other Peripheral and Cranial Neuropathies, Neuromuscular Disorders and Myopathies. 30th Annual Symposium of the European Society of Veterinary Neurology, Helsinki, Finland, 21-23 Sep 2017.
Rupp, A. et al. (2016) Complement-fixing Anti-ganglioside Antibodies in Acute Canine Polyradiculoneuritis. PNS/Inflammatory Neuropathy Consortium Meeting, Glasgow, UK, 21-25 Jun 2016.
Rupp, A. et al. (2015) The Sero-prevalence of Anti-glycolipid Antibodies in Acute Canine Polyradiculoneuritis and Other Peripheral and Cranial Neuropathies, Neuromuscular Disorders and Myopathies – Interim Report. 28th Annual Symposium of the European Society of Veterinary Neurology and European College of Veterinary Neurology, Amsterdam, The Netherlands, 18 Sep 2015.
Rupp, A., Yao, D., Meehan, G. R. and Willison, H. J. (2013) Thy-1 Mice Lend Themselves for the Modelling of Anti-ganglioside Antibody-mediated Disorders. PNS Biennial Meeting of the Peripheral Nerve Society, St Malo, France, 11-14 Jun 2013.
Rupp, A., Galban-Horcajo, F., Bianchi, E., Dondi, M., Penderis, J., Galluci, A. and Willison, H. J. (2012) Anti-ganglioside Antibodies as a Diagnostic Marker in Acute Canine Polyradiculoneuritis. 25th Annual Symposium of the European Society of Veterinary Neurology and European College of Veterinary Neurology, Ghent, Belgium, 13-15 Sep 2012.
Rupp, A., Galban-Horcajo, F., Bianchi, E., Dondi, M., Penderis, J. and Willison, H. J. (2012) Acute Canine Polyradiculoneuritis: A Naturally Occurring Model for Guillain-Barré Syndrome. PNS/Inflammatory Neuropathy Consortium Meeting, Rotterdam, The Netherlands, 24-27 Jun 2012.
Rupp, A., Morrison, I., Greenshields, K. and Willison, H. J. (2011) Harnessing In Vivo Imaging to Investigate Immune-mediated Disorders of the Neuromuscular Junction. 11th Course of the European School of Neuroimmunology, Glasgow, UK, 04-07 Nov 2011.
Rupp, A., Morrison, I., Halstead, S. K., Townson, K. H., Greenshields, K. N. and Willison, H. J. (2011) Rapid Deterioration and Steady Recovery of the Motor Nerve Terminal Integrity Following Complemenet-mediated Injury in a Murine Model of Guillain-Barré Syndrome. PNS Biennial Meeting of the Peripheral Nerve Society, Potomac, MD, USA, 25-29 Jun 2011.
Rupp, A. and Willison, H. J. (2010) Rapid Injury and Steady Recovery of the Neuromuscular Nerve Terminal Integrity After Application of Anti-ganglioside Antibody in a Murine Model of Guillain-Barré Syndrome. 10th International Congress of Neuroimmunology, Barcelona, Spain, 26-30 Oct 2010.
Rupp, A., Morrison, I., Halstead, S. K. and Willison, H. J. (2010) A Combination of In Vivo and Ex Vivo Imaging to Monitor Degeneration and Regeneration of the Murine Neuromuscular Junction Following Immune-mediated Injury. 23rd Annual Symposium of the European Society of Veterinary Neurology and European College of Veterinary Neurology, Cambridge, UK, 17-18 Sep 2010.
Rupp, A., Halstead, S. K. and Willison, H. J. (2008) Age-related Changes to the Distribution of Perisynaptic Schwann Cells at the Murine Neuromuscular Junction. 13th International Congress of the Federation of Societies for Histochemistry and Cytochemistry, Gdansk, Poland, 23-27 Aug 2008.
Grants
Grants and Awards listed are those received whilst working with the University of Glasgow.
- Pathophysiological factors in the diagnosis and treatment of the Guillain-Barre syndromes
Wellcome Trust
2017 - 2021
- ZikaPLAN
European Commission
2016 - 2019
- Zika virus- GBS: a joint Brazil-Colombia-UK infrastrucure project
Wellcome Trust
2016 - 2017
- Assocation studies with Guillain-Barre syndrome and neurotropism
Medical Research Council
2016 - 2017
- response to MRC ZIKA call
Medical Research Council
2016 - 2017
- Clinical and biological determinants of disease course in Guillain-Barre syndrome: the first analysis of the International Guillain-Barre syndrome Outcome Study (IGOS) biobank for GBS biomarkers.
Guillain-Barre & Associated Inflammatory Neuropathies
2016 - 2017
- Clinical and biological determinants of disease course in Guillain-Barre syndrome: a prospective UK-wide clinical initiative.
Guillain-Barre & Associated Inflammatory Neuropathies
2013 - 2014
- Defining the clinical relevance of demyelinating and axopathic autoantibodies in multiple sclerosis.
Action Medical Research
2013 - 2014
- Development of a high throughput combinatorial microarray platform for identifying novel glycolipid targets in inflammatory neuropahties
Peripheral Nerve Society
2013 - 2016
- Monitoring distal nerve degeneration and regeneration in an active immunization mouse model of Guillain-Barre syndrome
Peripheral Nerve Society
2011 - 2012
- The structural and functional diversity of anti-glycolipid antibody repertoires and their nerve binding domains in human autoimmune neuropathy
Wellcome Trust
2011 - 2016
- Neurofascin specific autoantibodies and the pathogenesis of MS
Multiple Sclerosis Society
2010 - 2013
- Anti-Sulphatide Antibodies in Multiple Sclerosis
NHS Greater Glasgow and Clyde
2010 - 2011
- Capacity Building Award in Integrative Mammalian Biology
Biotechnology and Biological Sciences Research Council
2010 - 2011
- Glycan Complexes as Novel Antigenic Targets in the Nervous System
Wellcome Trust
2008 - 2010
- Glycosphingolipid antigen depletion as a novel strategy for treating autoimmune peripheral nerve diseases
Medical Research Council
2008 - 2011
- Imaging brain metabolism in acute stroke patients
Patrick Berthould Charitable Trust
2007 - 2010
- An analysis of gangliocide specific B cells in autoimmune disease
Pathological Society of Great Britain and Ireland
2007 - 2010
- An integrated approach to novel mechanisms and therapeutic strategies in murine models of human autoimmune neuropathy
Wellcome Trust
2006 - 2011
- Phenotypic analysis and therapeutic modulation of murine autoimmune neuropathy
Patrick Berthould Charitable Trust
2004 - 2007
- Synthetic disialygalactose immunoadsorbents deplete anti-GQlb antibodies from autoimmune neuropathy sera
Guillain-Barre Syndrome Foundation International
2004 - 2006
- Glasgow Biomedical Research Centre
Wellcome Trust
2003 - 2006
- The Pathogenesis of Autoimmune Neuropathy Associated with Anti-ganglioside Antibodies
Wellcome Trust
2000 - 2006
Research datasets
2022
McGonigal, R. , Cunningham, M. , Smyth, D., Chou, M., Barrie, J., Wilkie, A., Campbell, C., Saatman, K. E., Lunn, M. and Willison, H. (2022) The endogenous calpain inhibitor calpastatin attenuates axon degeneration in murine Guillain-Barré syndrome. [Data Collection]
2020
Schultz, V. , Cumberworth, S., Gu, N., Johnson, N., Donald, C. , McCanney, G., Barrie, J., Da Silva Filipe, A. , Linington, C. , Willison, H. , Edgar, J., Barnett, S. and Kohl, A. (2020) Zika virus infection leads to demyelination and axonal injury in mature CNS cultures. [Data Collection]