Institute of Infection, Immunity and Inflammation

Dr Daniel Wall

  • Lecturer in Microbiology (Bacteriology)

telephone: 01413307123
email: Donal.Wall@glasgow.ac.uk


Bacterial manipulation of Programmed Cell Death (PCD) during infection facilitates the persistence of bacterial pathogens within host immune cells. This we believe contributes to the prolonged inflammation and severe pathology seen in many bacterial infections. By gaining an understanding of the mechanisms of bacterial targeting of these pathways we aim for therapeutic strategies to combat long term infection (Inflammatory Bowel Disease) and also to use the same knowledge to understand diseases where PCD is malfunctioning (cancer).


Research Group Home Page

List all by: Type | Date

Jump to: 2010
Number of items: 3.

2010

Wall, Daniel (2010) Salmonella pathogenesis and processing of secreted effectors by caspase-3. Other. Science.

Srikanth, C.V., Wall, D.M., Maldonado-Contreras, A., Shi, H.N., Zhou, D.G., Demma, Z., Mumy, K.L., and Mccormick, B.A. (2010) Salmonella Pathogenesis and Processing of Secreted Effectors by Caspase-3. Science, 330 (6002). pp. 390-393. ISSN 0036-8075 (doi:10.1126/science.1194598)

Wall, D.M., Srikanth, C.V., and McCormick, B.A. (2010) Targeting tumors with Salmonella Typhimurium - potential for therapy. Oncotarget, 1 (8). pp. 721-728. ISSN 1949-2553

This list was generated on Wed Jun 19 20:36:11 2013 BST.
Jump to: Article | Research Report or Paper
Number of items: 3.

Article

Srikanth, C.V., Wall, D.M., Maldonado-Contreras, A., Shi, H.N., Zhou, D.G., Demma, Z., Mumy, K.L., and Mccormick, B.A. (2010) Salmonella Pathogenesis and Processing of Secreted Effectors by Caspase-3. Science, 330 (6002). pp. 390-393. ISSN 0036-8075 (doi:10.1126/science.1194598)

Wall, D.M., Srikanth, C.V., and McCormick, B.A. (2010) Targeting tumors with Salmonella Typhimurium - potential for therapy. Oncotarget, 1 (8). pp. 721-728. ISSN 1949-2553

Research Report or Paper

Wall, Daniel (2010) Salmonella pathogenesis and processing of secreted effectors by caspase-3. Other. Science.

This list was generated on Wed Jun 19 20:36:11 2013 BST.

Grants and Awards listed are those received whilst working with the University of Glasgow.

  • Survival and dissemination of enteric pathogens through exploitation and inhibition of programmed cell death pathways in circulating immune cells.
    Biotechnology and Biological Sciences Research Council
    2013 - 2016
     
  • Deciphering and harnessing the activation of caspase-3 during infection by Salmonella typhimurium
    Society for General Microbiology
    2010 - 2010
     
  • Controlled induction of apoptotic enzymes by Salmonella typhimurium drives infection and inflammation
    Tenovus-Scotland
    2010 - 2011
     

Invited International Presentations

  • 2011: Tenovus Scotland - Sir Robert MacLellan Award
  • 2011: University of Strathclyde, UK - "Exploitation of apoptosis by Salmonella Typhimurium"
  • 2007: Washington D.C., USA - Experimental Biology Annual General Meeting - Identification of the Salmonella typhimurium SipA functional domain required for intestinal inflammation.
  • 2005: Long Island, NY, USA - Cold Spring Harbor Laboratory Microbial Pathogenesis & Host Response meeting. Cold Spring Harbor Laboratory - The S. typhimurium effector protein SipA possesses two discrete functional domains for invasion and inflammation

Prizes, Awards and Distinctions

  • 2010: Society for General Microbiology - President's Award

Research Fellowship

  • 2010 - 2010: University of Massachusetts, USA - Visiting Academic, University of Massachusetts Medical School, Molecular Genetics and Microbiology Department. Funded by the Society for General Microbiology, UK President's Fund.