Institute of Infection, Immunity and Inflammation

Prof Andy Waters

  • Professor (Parasitology)

telephone: 01413308720
email: Andy.Waters@glasgow.ac.uk


Prof Waters has >30 years experience in malaria research and together with Dr Janse helped pioneer the development of the rodent model of malaria research, Plasmodium berghei. The major objective of the laboratory is to understand the molecular developmental biology that is associated with sexual development. 

There are two main themes to the research:

1. Understanding the phenomenon of translational repression during sexual development and its role and importance for the further development of the fertilized zygote.

2. Triggers for gametocytogenesis. A transcription factor underpinning commitment to this critical event has been recently identified in the laboratory.  It’s mode of action and control of its expression are currently under study.

The laboratory analyses these issues using a polyomics approach which is institutionalised in Glasgow and includes metabolomics, parasite genetic manipulation and complemented by a fully functioning insectary.  Technology development is also a key part of our activities.

The laboratory currently has 5 post-doctoral researchers with a great range of molecular biological expertise, three technical support staff and three PhD students.  Our activities are complemented by three other research groups working on malaria or Toxoplasma and through our participation in the WTCMP of which Prof Waters is Director.  Together with the many other parasitological groups at Glasgow there is the greatest concentration and breadth of molecular parasitology expertise in the UK. The group participates mainly in Clusters 2 and 4.

The Waters‘ group consists of five post-doctoral research assistants and 3 technical support staff whose focus is on the molecular biology of sexual development of malaria parasites. Dr. Mhairi Stewart has extensive experience with RNA binding proteins in protozoa, Dr. Nisha Philip has extensive experience in signalling and miRNAs in Plasmodium; Dr Agnieszka Religa has extensive experience in parasite epigenetics; Dr Katie Hughes has extensive experience in Plasmodium cell biology and protozoan molecular biology and Dr Sonya Taylor has extensive experience in protozoan genetics and virulence.

Selected Publications

Hall, N., Karras, M., Raine, J.D., Carlton, J.M., Kooij, T.W.A., Berriman, M., Florens, L., Janssen, C., Pain, A., Christophides, C.K., James, K., Rutherford, K., Harris, B., Harris, D., Churcher, C., Quail, M.A., Ormond, D., Doggett, J., Trueman, H.E., Mendoza, J., Bidwell, S., Rajandream, M.A., Carucci, D.A., Yates, J.R. III, Kafatos, F.C., Janse, C.J., Barrell, B., Turner, C.M.R., Waters, A.P., Sinden, R.E. (2005) Science 307. 82-6. An integrated survey of gene expression during the life cycle of malaria parasites. (30.927)

Khan, S.M., Franke-Fayard, B., Mair, G.R., Lasonder, E., Janse, C.J, Mann, M. & Waters, A.P. (2005) Cell 121: 675-87. Proteome analysis of separated male and female gametocytes reveals novel sex specific Plasmodium biology. (29.431)

Mair, G.R. Braks, J.A.M., Garver, L.S., Wiegant, J.C.A.G., Hall, N., Dirks, R.W., Khan, S.M., Dimopoulos, G., Janse, C.J., Waters, A.P. (2006) Science 313. 667-9. Regulation of sexual development of Plasmodium by translational repression. (30.927)

Mair, G.R., Lasonder, E., Garver, L.S., Franke-Fayard, B., Carret, C.K., Wiegant, J., Dirks, R., Dimopoulos, G., Janse, C.J, Waters, A.P. (2010) PLoS Path. 6. e1000767. Universal features of post-transcriptional gene regulation are critical for Plasmodium zygote development. (9.079)

Iwanaga, S., Khan, S.M., Kaneko, I., Christodoulou, Z., Newbold, C.I., Yuda, M., Janse, C.J. & Waters, A.P. (2010) Cell Host Microbe, 7, 245-255. Functional Identification of the Plasmodium Centromere and Generation of a Plasmodium Artificial Chromosome. (13.728)

Number of original publications since 2008: 31
Number of joint publications (with NoE partners): 21

Jump to: 2012 | 2011 | 2010 | 2009 | 2008
Number of items: 39.

2012

Religa, A.A., and Waters, A.P. (2012) Sirtuins of parasitic protozoa: in search of function(s). Molecular and Biochemical Parasitology, 185 (2). pp. 71-88. ISSN 0166-6851 (doi:10.1016/j.molbiopara.2012.08.003)

Reboud, J., Bourquin, Y., Wilson, R., Pall, G.S., Jiwaji, M., Pitt, A.R., Graham, A., Waters, A.P., and Cooper, J.M. (2012) Shaping acoustic fields as a toolset for microfluidic manipulations in diagnostic technologies. Proceedings of the National Academy of Sciences of the United States of America, 109 (38). pp. 15162-15167. ISSN 0027-8424 (doi:10.1073/pnas.1206055109)

Orr, R.Y., Philip, N., and Waters, A.P. (2012) Improved negative selection protocol for Plasmodium berghei in the rodent malarial model. Malaria Journal, 11 (103). ISSN 1475-2875 (doi:10.1186/1475-2875-11-103)

Philip, N., Vaikkinen, H.J., Tetley, L., and Waters, A.P. (2012) A unique kelch domain phosphatase in plasmodium regulates ookinete morphology, motility and invasion. PLoS ONE, 7 (9). e44617. ISSN 1932-6203 (doi:10.1371/journal.pone.0044617)

Ramakrishnan, C., Rademacher, A., Soichot, J., Costa, G., Waters, A.P., Janse, C.J., Ramesar, J., Franke-Fayard, B.M., and Levashina, E.A. (2012) Salivary gland-specific P. berghei reporter lines enable rapid evaluation of tissue-specific sporozoite loads in mosquitoes. PLoS ONE, 7 (5). e36376. ISSN 1932-6203 (doi:10.1371/journal.pone.0036376)

2011

Laurentino, E.C. et al. (2011) Experimentally controlled downregulation of the histone chaperone FACT in Plasmodium berghei reveals that it is critical to male gamete fertility. Cellular Microbiology, 13 (12). pp. 1956-1974. ISSN 1462-5814 (doi:10.1111/j.1462-5822.2011.01683.x)

Fonager, J., Franke-Fayard, B.M.D., Adams, J.H., Ramesar, J., Klop, O., Khan, S.M, Janse, C.J., and Waters, A.P. (2011) Development of the piggyBac transposable system for Plasmodium berghei and its application for random mutagenesis in malaria parasites. BMC Genomics, 12 (155). pp. 1-17. ISSN 1471-2164 (doi:10.1186/1471-2164-12-155)

Gomes-Santos, C.S.S. et al. (2011) Transition of plasmodium sporozoites into liver stage-like forms is regulated by the RNA binding protein pumilio. PLoS Pathogens, 7 (5). e1002046. ISSN 1553-7366 (doi:10.1371/journal.ppat.1002046)

Hills, T., Srivastava, A., Ayi, K., Wernimont, A.K., Kain, K., Waters, A.P., Hui, R., and Pizarro, J.C. (2011) Characterization of a new phosphatase from Plasmodium. Molecular and Biochemical Parasitology, 179 (2). pp. 69-79. ISSN 0166-6851 (doi:10.1016/j.molbiopara.2011.06.001)

Sicard, A. et al. (2011) Activation of a PAK-MEK signalling pathway in malaria parasite-infected erythrocytes. Cellular Microbiology, 13 (6). pp. 836-845. ISSN 1462-5814 (doi:10.1111/j.1462-5822.2011.01582.x)

Wykes, M.N. et al. (2011) Rodent blood-stage Plasmodium survive in dendritic cells that infect naive mice. Proceedings of the National Academy of Sciences, 108 (27). pp. 11205-11210. ISSN 0027-8424 (doi:10.1073/pnas.1108579108)

2010

van Dijk, M.R. et al. (2010) Three members of the 6-cys protein family of Plasmodium play a role in gamete fertility. PLoS Pathogens, 6 (6). e1000853. ISSN 1553-7366 (doi:10.1371/journal.ppat.1000853)

Iwanaga, S., Khan, S.M., Kaneko, I., Christodoulou, Z., Newbold, C.N., Yuda, M., Janse, C.J., and Waters, A.P. (2010) Functional identification of the Plasmodium centromere and generation of a Plasmodium artificial chromosome. Cell Host and Microbe, 7 (3). pp. 245-255. ISSN 1931-3128 (doi:10.1016/j.chom.2010.02.010)

Starnes, G. L., and Waters, A.P. (2010) Home improvements: how the malaria parasite makes the red blood cell home sweet home. Journal of Molecular Cell Biology, 2 (1). pp. 11-13. ISSN 1674-2788 (doi:10.1093/jmcb/mjp024)

Bopp, S.E.R. et al. (2010) Genome wide analysis of inbred mouse lines identifies a locus containing Ppar-Ī³ as contributing to enhanced malaria surviva. PLoS ONE, 5 (5). e10903. ISSN 1932-6203 (doi:10.1371/journal.pone.0010903)

Goldberg, D. E., Janse, C.J., Cowman, A. F., and Waters, A.P. (2010) Has the time come for us to complement our malaria parasites? Trends in Parasitology, 27 (1). pp. 1-2. ISSN 1471-4922 (doi:10.1016/j.pt.2010.06.017)

Hughes, K.R., Philip, N., Lucas Starnes, G., Taylor, S., and Waters, A.P. (2010) From cradle to grave: RNA biology in malaria parasites. Wiley Interdisciplinary Reviews - RNA, 1 (2). pp. 287-303. ISSN 1757-7004 (doi:10.1002/wrna.30)

Janse, C.J., Kroeze, H., van Wigcheren, A., Mededovic, S., Fonager, J., Franke-Fayard, B., Waters, A.P., and Khan, S.H. (2010) A genotype and phenotype database of genetically modified malaria-parasites. Trends in Parasitology, 27 (1). pp. 31-39. ISSN 1471-4922 (doi:10.1016/j.pt.2010.06.016)

Mair, G.R. et al. (2010) Universal features of post-transcriptional gene regulation are critical for Plasmodium zygote development. PLoS Pathogens, 6 (2). e1000767. ISSN 1553-7366 (doi:10.1371/journal.ppat.1000767)

Ploemen , I.H.J. et al. (2010) Visualisation and quantitative analysis of the rodent malaria liver stage by real time imaging. PLoS ONE, 4 (11). e7881. ISSN 1932-6203 (doi:10.1371/journal.pone.0007881)

Spaccapelo, R. et al. (2010) Plasmepsin 4-deficient Plasmodium berghei are virulence attenuated and induce protective immunity against experimental malaria. American Journal of Pathology, 176 (1). pp. 205-217. ISSN 0002-9440 (doi:10.2353/ajpath.2010.090504)

2009

Ponzi, M. et al. (2009) Egress of Plasmodium berghei gametes from their host erythrocyte is mediated by the MDV-1/PEG3 protein. Cellular Microbiology, 11 (8). pp. 1272-1288. ISSN 1462-5814 (doi:10.1111/j.1462-5822.2009.01331.x)

Tufet-Bayona, M., Janse, C.J., Khan, S.M., Waters, A.P., Sinden, R.E., and Franke-Fayard, B. (2009) Localisation and timing of expression of putative Plasmodium berghei rhoptry proteins in merozoites and sporozoites. Molecular and Biochemical Parasitology, 166 (1). pp. 22-31. ISSN 0166-6851 (doi:10.1016/j.molbiopara.2009.02.009)

Vega-Rodriguez, J., Franke-Fayard, B., Dinglasan, R.R., Janse, C.J., Pastrana-Mena, R., Rodriguez-Orengo, J.F., Jacobs-Lorena, M., Serrano, A.E., Waters, A., and Srinivasan , P. (2009) The glutathione biosynthetic pathway of Plasmodium is essential for mosquito transmission. PLoS Pathogens, 5 (2). e1000302. ISSN 1553-7366 (doi:10.1371/journal.ppat.1000302)

Baum, J., Papenfuss, A.T., Mair, G.R., Janse, C.J., Vlachou, D., Waters, A.P., Cowman, A.F., Crabb, B.S., and Koning-Ward, T.F. (2009) Molecular genetics and comparative genomics reveal RNAi is not functional in malaria parasites. Nucleic Acids Research, 37 (11). pp. 3788-3798. ISSN 0305-1048 (doi:10.1093/nar/gkp239)

Dobson, Sarah E., Augustijn, Kevin D., Brannigan, James A., Schnick, Claudia, Janse, Chris J., Dodson, Eleanor J., Waters, A.P., and Wilkinson, Anthony J. (2009) The crystal structures of macrophage migration inhibitory factor fromPlasmodium falciparumandPlasmodium berghei. Protein Science, 18 (12). pp. 2578-2591. ISSN 0961-8368 (doi:10.1002/pro.263)

Lavazec, C., Moreira, C.K., Mair, G.R., Waters, A.P., Janse, C.J., and Templeton, T.J. (2009) Analysis of mutant Plasmodium berghei parasites lacking expression of multiple PbCCp genes. Molecular and Biochemical Parasitology, 163 (1). pp. 1-7. ISSN 0166-6851 (doi:10.1016/j.molbiopara.2008.09.002)

Moon, R.W., Taylor, C.J., Bex, C., Schepers, R., Goulding, D., Janse, C.J., Waters, A.P., Baker, D.A., and Billker, O. (2009) A cyclic GMP signalling module that regulates gliding motility in a malaria parasite. PLoS Pathogens, 5 (9). e1000599. ISSN 1553-7366 (doi:10.1371/journal.ppat.1000599)

Yuda, M., Iwanaga, S., Shigenobu, S., Mair, G.R., Janse, C.J., Waters, A.P., Kato, T., and Kaneko, I. (2009) Identification of a transcription factor in the mosquito-invasive stage of malaria parasites. Molecular Microbiology, 71 (6). pp. 1402-1414. ISSN 0950-382X (doi:10.1111/j.1365-2958.2009.06609.x)

2008

Yu, M. et al. (2008) The fatty acid biosynthesis enzyme fabi plays a key role in the development of liver stage malarial parasites. Cell Host and Microbe, 4 (6). pp. 567-568. ISSN 1931-3128 (doi:10.1016/j.chom.2008.11.001)

Braks, J.A.M., Mair, G.R., Franke-Fayard, B., Janse, C.J., and Waters, A.P. (2008) A conserved U-rich RNA region implicated in regulation of translation in Plasmodium female gametocytes. Nucleic Acids Research, 36 (4). pp. 1176-1186. ISSN 0305-1048 (doi:10.1093/nar/gkm1142)

van Schaijk, B. C. L. et al. (2008) Gene disruption of Plasmodium falciparum p52 results in attenuation of malaria liver stage development in cultured primary human hepatocytes. PLoS ONE, 3 (10). e3549. ISSN 1932-6203 (doi:10.1371/journal.pone.0003549)

Braks, J.A.M., Mair, G.R., Franke-Fayard, B., Janse, C.J., and Waters, A.P. (2008) A conserved U-rich RNA region implicated in regulation of translation in Plasmodium female gametocytes. Nucleic Acids Research, 36 (4). pp. 1176-1186. ISSN 1362-4962 (doi:10.1093/nar/gkm1142)

Di Girolamo, F. et al. (2008) Plasmodium lipid rafts contain proteins implicated in vesicular trafficking and signalling as well as members of the PIR superfamily, potentially implicated in host immune system interactions. Proteomics, 8 (12). pp. 2500-2513. ISSN 1615-9853 (doi:10.1002/pmic.200700763)

Franke-Fayard, B., Djokovic, D., Dooren, M.W., Ramesar, J., Waters, A.P., Falade, M.O., Kranendonk, M., Martinelli, A., Cravo, P., and Janse, C.J. (2008) Simple and sensitive antimalarial drug screening in vitro and in vivo using transgenic luciferase expressing Plasmodium berghei parasites. International Journal for Parasitology, 38 (14). pp. 1651-1662. ISSN 0020-7519 (doi:10.1016/j.ijpara.2008.05.012)

Lasonder, E. et al. (2008) Proteomic profiling of Plasmodium sporozoite maturation identifies new proteins essential for parasite development and infectivity. PLoS Pathogens, 4 (10). e1000195 . ISSN 1553-7366 (doi:10.1371/journal.ppat.1000195)

Moreira, C.K., Templeton, T.J., Lavazec, C., Hayward, R.E., Hobbs, C.V., Kroeze, H., Janse, C.J., Waters, A.P., Sinnis, P., and Coppi, A. (2008) The Plasmodium TRAPMIC2 family member, TRAP-Like Protein (TLP), is involved in tissue traversal by sporozoites. Cellular Microbiology, 10 (7). pp. 1505-1516. ISSN 1462-5814 (doi:10.1111/j.1462-5822.2008.01143.x)

Waters, A.P. (2008) Genome-informed contributions to malaria therapies: feeding somewhere down the (pipe)line. Cell Host and Microbe, 3 (5). pp. 280-283. ISSN 1931-3128 (doi:10.1016/j.chom.2008.04.005)

van Ooij, C. et al. (2008) The malaria secretome: from algorithms to essential function in blood stage infection. PLoS Pathogens, 4 (6). e1000084. ISSN 1553-7366 (doi:10.1371/journal.ppat.1000084)

This list was generated on Fri May 3 05:39:00 2013 BST.

Grants and Awards listed are those received whilst working with the University of Glasgow.

  • Wellcome Open Access Award
    Wellcome Trust
    2013 - 2013
     
  • Institutional Strategic Support Fund (ISSF)
    Wellcome Trust
    2012 - 2014
     
  • ParaMet - A systematic approach to understanding parasite metabolism.
    European Commission
    2012 - 2016
     
  • Ozmalnetā??TOWARDS THE ESTABLISHMENT OF A FRAMEWORK IN MALARIA BETWEEN THE AMRN AND EVIMALAR
    European Commission
    2012 - 2014
     
  • Integrated Health - Polyomics and Systems Biomedicine (ISSF Bid)
    Wellcome Trust
    2011 - 2014
     
  • RSE International Exhange Programme: IEP Open - Incoming
    Royal Society of Edinburgh
    2010 - 2010
     
  • Evimalar
    European Commission
    2009 - 2014
     
  • Search for optimised inhibitors of Plasmodium falciparum
    Medicines for Malaria Venture
    2008 - 2008
     
  • Conditional translational repression: a core regulatory mechanism of gene expression during development of the malaria parasite.
    Wellcome Trust
    2008 - 2015
     

Editorial Board

  • 2005 - ongoing: Future Microbiology - Member Editorial Advisory Board
  • 2001 - ongoing: Molecular & Biochemical Parasitology - Executive Editor
  • 2000 - 2005: Molecular & Biochemical Parasitology - Member Editorial Board & Reviews Editor
  • 1998 - 2008: Trends in Parasitology - Member Editorial Advisory Board

Grant Advisory Board

  • 2009 - 2014: Biomalpar - Director Biomalpar, a European Community-funded Network of Excellence
  • 2007 - 2007: WHO/TDR - Consultant to Steering Committee on Pathogenesis and Applied Genomics
  • 2007 - 2007: Wellcome Trust - Member External review Committee for PhD Programme
  • 2007 - 2007: International Livestock Research Institute (ILRI) - Consultant on development of anti-parasitic diagnostics and vaccines in the post-genomic era.
  • 2006 - 2006: French Medical Research Council (INSERM) - Appointed INSERM expert peer reviewer
  • 2006 - 2008: WHO/TDR - PLUS Review panel member for parasite applied genomics
  • 2006 - 2008: Nederlandse Organisatie voor Wetenschappelijke Onderzoek (NWO) - Rubicon award, review panel member
  • 2006 - 2009: European ANTIMAL Network - Member of External Scientific Advisory Committee
  • 2005 - ongoing: WHO - Member Parasite Transfection Task Force and Drug Resistance
  • 2004 - 2009: European Commission Framework VI - Member Executive Scientific Steering Committee and Scientific Cluster Co-ordinator, Network of Excellence, Biology of Malaria Parasites (BIOMALPAR)
  • 2002 - 2005: The Malaria Research and Reference Reagent Resource Center (MR4) - Member Scientific Advisory Panel, MR4, ATCC, Manassas, VA, USA
  • 2001 - 2001: Institut Pasteur - Member, External Evaluation Committee, Department of Immunology
  • 2001 - 2007: Nederlandse Organisatie voor Wetenschappelijke Onderzoek (NWO) - Member, Microbiology Grants Panel, Aard-en Levenswetenschappen (ALW)
  • 2001 - 2004: Wellcome Trust - Member, Infection & Immunity Panel

Invited International Presentations

  • 2009: Baltimore, MD, USA - Invited Speaker, 7th Malaria Conference of the Malaria Institute, Johns Hopkins University
  • 2009: Oxford, UK, - Invited Speaker, Malaria Gordon Conference
  • 2009: Aberdeen, Scotland - Invited Speaker, University of Aberdeen, Department of Medical Microbiology
  • 2009: Woods Hole, MA, USA - Invited Speaker, Biology of Parasitism
  • 2008: Rhode Island, USA - Invited Speaker, Gordon Research Conference on the Biology of Host-Parasite Interactions
  • 2008: Alpbach, Austria - Invited Speaker Keystone Symposium on Malaria: Immunology, Pathogenesis and Vaccine Perspectives
  • 2008: Melbourne, Australia - Invited Speaker, (of 3) at GTAC ? the Genome Technology Access Centre. Presentation made to an invited audience of High School students
  • 2008: Brussels, Belgium - White paper author and rapporteur at "Challenges for the Future: Research on HIV/AIDS, Malaria and Tuberculosis" FP7 policy conference for FP8
  • 2008: Singapore, - Invited Speaker, 2nd Malaria Conference, Nangyang TU
  • 2008: Lorne, Australia - Invited Speaker, 3rd MAM Conference
  • 2008: Woods Hole, MA, USA - Invited Speaker Biology of Parasitism
  • 2007: Arnhem, The Netherlands - Invited Speaker Dutch Microbiology Society Annual Meeting
  • 2007: Bern, Switzerland - Invited Speaker University of Bern Graduate School Cell Biology
  • 2007: St. Louis, USA - Invited Speaker ? Department of Microbiology, Washington University
  • 2007: Salvador, Bahia, Brazil - Invited Speaker, XXXVI Annual Meeting of the Brazilian Society of Biochemistry and Molecular Biology (SBBq)
  • 2007: Bangkok, Thailand, - Course Faculty, Malaria Parasite Transfection Workshop
  • 2007: San Feliu de Guixols, SPAIN - Invited Speaker, 2nd ESF-EMBO Symposium Comparative Genomics of Eukaryotic Microorganisms: Eukaryotic Genome Evolution from Yeasts to Parasites and Pathogens?.
  • 2007: Leiden, The Netherlands - Invited speaker, Centre of Infectious Diseases symposium, Leiden University Medical Centre
  • 2007: Siena, Italy - Invited Speaker 1st Global Novartis Infectious Disease Meeting
  • 2007: Woods Hole, MA, USA - Invited Speaker, Biology of Parasitism Course, MBL
  • 2006: Rhode Island, USA - Invited Speaker, Gordon Research Conference on the Biology of Host-Parasite Interactions
  • 2006: Dresden, Germany - Speaker, COST 857 Conference
  • 2006: Glasgow, Scotland - Invited Speaker, Biology of Parasitism Course, MBL
  • 2006: Matsuyama, Japan - Invited Speaker, Matsuyama International Symposium on Cell-Free Sciences
  • 2006: Leiden, The Netherlands - Invited Speaker, Federation of Biomedical Scientific Societies (FMWV-NWO),
  • 2006: Atlanta, Georgia, USA. - Invited Speaker, ?Knockouts (and knock-ins) in parasites: promises and challenges? pre-meeting workshop of the American Society of Tropical Medicine and Hygiene (ASTMH) meeting
  • 2006: Heidleberg, Germany - Lead organiser, EU FP6 NoE BIOMALPAR Annual Meeting
  • 2006: Taos, New Mexico - Invited Speaker, Keystone Symposium on Malaria: Functional Genomics to Biology to Medicine
  • 2006: Singapore - External Examiner, Thesis Jaysree Iyer, University of Nan-Yang
  • 2006: Dundee, Scotland - Invited Speaker, University of Dundee
  • 2006: Jerusalem, Israel - Invited Speaker, workshop on Severe Malaria, Israeli Society for Parasitology, Protozoology and Tropical Diseases (ISPPTD)
  • 2006: Puerto Rico - Invited Speaker, University of Puerto Rico
  • 2006: Glasgow, Scotland - Invited Speaker, University of Glasgow, Division of Life Sciences
  • 2006: Woods Hole, MA, USA - Invited Speaker, Biology of Parasitism Course, MBL
  • 2005: Washington DC, USA - Invited Speaker, Plasmodium pre-erythrocytic development; genomic/proteomic approaches to intervention
  • 2005: Boston, USA - Invited participant, ?Future of Malaria Genomics?. Policy forum sponsored by Burroughs Wellcome Fund and Wellcome Trust
  • 2005: Oxford, England - Chairman, Gordon Research Conference on Malaria
  • 2005: Oxford, England - Organiser and Chairman, Malaria Gordon Conference
  • 2005: Woods Hole, MA, USA - Co-organiser, Molecular Parasitology Meeting
  • 2005: New Delhi, India - Course Faculty, Malaria Parasite Transfection Workshop
  • 2005: Veyrier du Lac, France - Invited Panelist, Meeting, ?Future of Anti-Parasitic Vaccines?, Merieux Foundation
  • 2005: Woods Hole, MA, USA, - Invited Speaker, Biology of Parasitism course
  • 2005: San Feliu de Guixols - Invited Speaker ESF-EMBO Conference, Comparative genomics of eukaryotic microorganisms: eukaryotic genome evolution, approaches with yeasts and fungi.
  • 2004: Baltimore MD, USA - Invited Speaker, 2nd Malaria Conference of the Malaria Institute, Johns Hopkins University
  • 2004: Melbourne, Australia - Invited speaker at Walter and Elisa Hall Institute
  • 2004: Singapore - Invited Speaker, Molecular Approaches to Malaria, Nanyang Technological University, Singapore
  • 2004: London, England - Invited Speaker, Keynote Lecture Series, NIMR, Mill Hill
  • 2004: Woods Hole, MA, USA - 2004-6 Co-organiser, Molecular Parasitology Meeting
  • 2004: Bangkok, Thailand - Invited Speaker and Discussant, WHO Workshop, "The impact of genetic engineering of Plasmodium on parasite drug resistance"
  • 2004: Les Treilles, France - 2004 Invited participant in New Frontiers in Malaria Parasite and Anopheles Mosquito Engineering, Fondation des Treilles
  • 2004: Lorne, Australia - Speaker & Session Chair, MAM04
  • 2004: Miami, USA - Invited Speaker, Symposium on ?Transmission Blocking Vaccines", ASTMH Meeting
  • 2004: Paris, France - Invited Speaker at "Dynamic Imaging Microscopy & Analysis for Biologists" Workshop held at Institut Pasteur
  • 2004: Woods Hole, MA, USA - Invited Speaker, Biology of Parasitism course
  • 2004: Chester, England - Invited Keynote Speaker, British Society for Parasitology, Annual meeting
  • 2003: Paris, France - Plenary Speaker, European Conference on Computational Biology 2003
  • 2003: Glasgow, Scotland - Invited Speaker, Wellcome Institute for Parasitology Lecture Series, University of Glasgow
  • 2003: Odense, Denmark - Invited Speaker, University of Southern Denmark
  • 2003: Utrecht, The Netherlands - Invited Speaker, Dutch Microbiological Society, de Uithof
  • 2003: Kindrogan, Scotland - British Society for Parasitology Kindrogan Speaker, SUMP
  • 2003: Manchester, England - Symposium speaker, "Post Genomics Applied to Processes: Advances in Eukaryotic Microbiology", Society for General Microbiology
  • 2003: Oxford, UK - Vice chairman, Gordon Research Conference on Malaria
  • 2003: Heidelberg, Germany - Invited speaker, ZDF Spearpoint programme, University of Heidelberg
  • 2003: Edinburgh, Scotland - Invited speaker, University of Edinburgh
  • 2003: Oxford, England - Vice chairman, Gordon Research Conference on Malaria
  • 2003: Aubiere, France - Plenary Speaker, Bienniale Reunion Protozologists
  • 2003: Amsterdam, The Netherlands - Symposium speaker, ?Phacilitate? Vaccine development Congress
  • 2002: Umea, Sweden - Speaker, external lecture series, University of Umea
  • 2002: Stockholm, Sweden - Invited Speaker, Pathology of Malaria, Meeting, Karolinska Institute
  • 2002: Woods Hole, MA, USA - Invited speaker, Molecular Parasitology Course
  • 2002: Kidrogan, Scotland - Plenary speaker, SUMP
  • 2002: Tucson, AZ, USA - Invited speaker, Vector Pathogen interactions meeting
  • 2002: Woods Hole, MA, USA - Session Chair, Molecular Parasitology Meeting
  • 2001: Woods Hole, MA, USA - Invited speaker, Molecular Parasitology Course
  • 2001: Oxford, England - Invited speaker, Gordon Malaria Conference
  • 2001: Hinxton, England - Invited participant, 11th Malaria Genome Meeting, Wellcome Trust
  • 2001: London, England - Invited Speaker, ?Functional Genomics of Protozoan Parasites?, Royal Society of Great Britain
  • 2001: Keele, England - Plenary Speaker, British Society for Parasitology

Prizes, Awards and Distinctions

  • 2008: Wellcome Trust Principal Research Fellow
  • 2006: Visiting Professor, Edinburgh University, Scotland, UK
  • 2003: Honorary Reader, Imperial College, London, UK
  • 2001: Visiting Fellow, Gulbenkian Institute of Science, Oeiras, Portugal

Professional Learned Society

  • 2010 - ongoing: Royal Society of Edinburgh - Fellow
  • 2009 - ongoing: European Molecular Biology Organisation - Elected Member
  • 2009 - ongoing: Society for General Microbiology
  • 2000 - 2008: British Society for Parasitology
  • 1998 - 2007: Dutch Parasitological Society (NVP)
  • 1996 - 2001: Royal Society of Tropical Medicine and Hygiene

Research Fellowship

  • 2008 - 2015: Wellcome Trust Principal Research Fellowship