Dr Andrew Roe

  • Senior Lecturer (Bacteriology)

telephone: 01413302980
email: Andrew.Roe@glasgow.ac.uk

Research interests

 

Regulation and expression of virulence factors in enterohaemorraghic Escherichia coli (EHEC) O157:H7.

Research Group Home Page

Personal Profile on ResearchGate

Grants

Grants and Awards listed are those received whilst working with the University of Glasgow.

  • Characterisation of the role of AdhE in regulation of virulence in Escherichia coli O157:H7
    Tenovus-Scotland
    2013 - 2014
     
  • Utility of LOV-based Fluorescent Reporters To Monitor the Real-Time Secretion and Localisation of Bacterial Effector Proteins
    BBSRC
    2010 - 2011
     
  • Identification of proteins targeted by salicylic aldehyde inhibitors in Escherichia coli O157
    Medical Research Scotland
    2009 - 2010
     
  • A biochemical and molecular analysis of the YhaO membrane protein in Escherichia coli O157:H7
    BBSRC
    2009 - 2012
     
  • Development and evaluation of fluorescent Light Oxygen-Voltage (LOV) domains for monitoring bacterial protein translocation
    Royal Society
    2008 - 2009
     
  • Characterisation of novel inhibitors of type three secretion systems in Escherichia coli O157
    Tenovus-Scotland
    2008 - 2008
     

Publications

List by: Type | Date

Jump to: 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006 | 2005 | 2004 | 2003 | 2002 | 2001
Number of items: 50.

2014

Beckham, K. S.H., and Roe, A. J. (2014) From screen to target: insights and approaches for the development of anti-virulence compounds. Frontiers in Cellular and Infection Microbiology, 4 (139). ISSN 2235-2988 (doi:10.3389/fcimb.2014.00139)

Beckham, K. S.H. et al. (2014) The metabolic enzyme AdhE controls the virulence of Escherichia coli O157:H7. Molecular Microbiology, 93 (1). pp. 199-211. ISSN 0950-382X (doi:10.1111/mmi.12651)

2013

Dunne, K.A. et al. (2013) Increased S-nitrosylation and proteasomal degradation of caspase-3 during infection contribute to the persistence of adherent invasive escherichia coli (AIEC) in immune cells. PLoS ONE, 8 (7). e68386. ISSN 1932-6203 (doi:10.1371/journal.pone.0068386)

Gabrielsen, M., Roe, A.J., and McLuskey, K. (2013) High-throughput methods for the detection of protein overexpression using fluorescence markers. Methods in Cell Biology, 113 . pp. 189-208. ISSN 0091-679X (doi:10.1016/B978-0-12-407239-8.00010-0)

Othman, S., Roe, A.J., Parton, R., and Coote, J.G. (2013) Use of a dual reporter plasmid to demonstrate bactofection with an attenuated aroa- derivative of Pasteurella multocida b:2. PLoS ONE, 8 (8). e71524. ISSN 1932-6203 (doi:10.1371/journal.pone.0071524)

2012

Tahoun, A. et al. (2012) Salmonella transforms follicle-associated epithelial cells into M cells to promote intestinal invasion. Cell Host and Microbe, 12 (5). pp. 645-656. ISSN 1931-3128 (doi:10.1016/j.chom.2012.10.009)

Gabrielsen, M., Rey-Burusco, M.F., Griffiths, K., Roe, A.J., Cooper, A., Smith, B.O., Kennedy, M.W., and Corsico, B. (2012) Two crystal forms of a helix-rich fatty acid- and retinol-binding protein, Na-FAR-1, from the parasitic nematodeNecator americanus. Acta Crystallographica. Section F: Structural Biology and Crystallization Communications, 68 (7). pp. 835-838. ISSN 1744-3091 (doi:10.1107/S1744309112023597)

Beckham, K.S.H., Byron, O., Roe, A.J., and Gabrielsen, M. (2012) The structure of an orthorhombic crystal form of a 'forced reduced' thiol peroxidase reveals lattice formation aided by the presence of the affinity tag. Acta Crystallographica. Section F: Structural Biology and Crystallization Communications, 68 (5). pp. 522-526. ISSN 1744-3091 (doi:10.1107/S1744309112011487)

Beckham, K.S., Byron, O., Roe, A.J., and Gabrielsen, M. (2012) The structure of an orthorhombic crystal form of a `forced reduced' thiol peroxidase reveals lattice formation aided by the presence of the affinity tag. Acta Crystallographica. Section F: Structural Biology and Crystallization Communications, 68 (5). pp. 522-526. ISSN 1744-3091 (doi:10.1107/S1744309112011487)

Christie, J.M., Gawthorne, J., Young, G., Fraser, N.J., and Roe, A.J. (2012) LOV to BLUF: flavoprotein contributions to the optogenetic toolkit. Molecular Plant . ISSN 1674-2052 (doi:10.1093/mp/sss020)

Gabrielsen, M., Beckham, K.S., Feher, V.A., Zetterstrom, C.E., Wang, D., Muller, S., Elofsson, M., Amaro, R.E., Byron, O., and Roe, A.J. (2012) Structural characterisation of Tpx from yersinia pseudotuberculosis reveals insights into the binding of salicylidene acylhydrazide compounds. PLoS ONE, 7 (2). e32217. ISSN 1932-6203 (doi:10.1371/journal.pone.0032217)

Gabrielsen, M., Beckham, K.S.H., Cogdell, R.J., Byron, O., and Roe, A.J. (2012) FolX from Pseudomonas aeruginosa is octameric in both crystal and solution. FEBS Letters, 586 (8). pp. 1160-1165. ISSN 0014-5793 (doi:10.1016/j.febslet.2012.03.031)

Gabrielsen, M., Beckham, K.S.H., and Roe, A.J. (2012) High-throughput methods for the identification of protein purification conditions using a cleavable tag system. Methods in Cell Biology, 112 . pp. 93-110. ISSN 0091-679X (doi:10.1016/B978-0-12-405914-6.00005-6)

Gabrielsen, M., Riboldi-Tunnicliffe, A., Ibáñez-Shimabukuro, M., Griffiths, K., Roe, A.J., Cooper, A., Smith, B., Córsico, B., and Kennedy, M.W. (2012) Useable diffraction data from a multiple microdomain-containing crystal of Ascaris suum As-p18 fatty-acid-binding protein using a microfocus beamline. Acta Crystallographica. Section F: Structural Biology and Crystallization Communications, 68 . pp. 939-941. ISSN 1744-3091 (doi:10.1107/S1744309112026553)

Gabrielsen, M., Riboldi-Tunnicliffe, A., Ibáñez-Shimabukuro, M., Griffiths, K., Roe, A.J., Cooper, A., Smith, B.O., Córsico, B., and Kennedy, M.W. (2012) Useable diffraction data from a multiple microdomain-containing crystal ofAscaris suumAs-p18 fatty-acid-binding protein using a microfocus beamline. Acta Crystallographica. Section F: Structural Biology and Crystallization Communications, 68 (8). pp. 939-941. ISSN 1744-3091 (doi:10.1107/S1744309112026553)

Gawthorne, J.A., Reddick, L.E., Akpunarlieva, S.N., Beckham, K.S.H., Christie, J.M., Alto, N.M., Gabrielsen, M., and Roe, A.J. (2012) Express your LOV: an engineered flavoprotein as a reporter for protein expression and purification. PLoS ONE, 7 (12). e52962. ISSN 1932-6203 (doi:10.1371/journal.pone.0052962)

Schmidt, E.E., Holmes, A., Lindestam Arlehamn, C.S., Wang, D., Mitchell, T.J., Evans, T.J., and Roe, A.J. (2012) Expression and regulation of the Escherichia coli O157:H7 effector proteins NleH1 and NleH2. PLoS ONE, 7 (3). e33408. ISSN 1932-6203 (doi:10.1371/journal.pone.0033408)

Xuefang, X. et al. (2012) Lysogeny with Shiga toxin 2-encoding bacteriophages represses type III secretion in enterohemorrhagic Escherichia coli. PLoS Pathogens, 8 (5). e1002672. ISSN 1553-7366 (doi:10.1371/journal.ppat.1002672)

2011

Gabrielsen, M., Kroner, F., Black, I., Isaacs, N.W., Roe, A.J., and McLuskey, K. (2011) High-throughput identification of purification conditions leads to preliminary crystallization conditions for three inner membrane proteins. Molecular Membrane Biology, 28 (7-8). pp. 445-453. ISSN 0968-7688 (doi:10.3109/09687688.2011.628954)

Wang, D. et al. (2011) Identification of bacterial target proteins for the salicylidene acylhydrazide class of virulence blocking compounds. Journal of Biological Chemistry, 286 (34). pp. 29922-29931. ISSN 0021-9258 (doi:10.1074/jbc.M111.233858)

Tree, J.J. et al. (2011) Transcriptional regulators of the GAD acid stress island are carried by effector protein-encoding prophages and indirectly control type III secretion in enterohemorrhagic Escherichia coli O157:H7. Molecular Microbiology, 80 (5). pp. 1349-1365. ISSN 0950-382X (doi:10.1111/j.1365-2958.2011.07650.x)

2010

Gabrielsen, M., Zetterström, C.E., Wang, D., Beckham, K.S.H., Elofsson, M., Isaacs, N.W., and Roe, A. (2010) Expression, purification, crystallization and initial X-ray diffraction analysis of thiol peroxidase from Yersinia pseudotuberculosis. Acta Crystallographica. Section F: Structural Biology and Crystallization Communications, 66 (12). pp. 1606-1609. ISSN 1744-3091 (doi:10.1107/S1744309110039679)

Holmes, A., Muhlen, S., Roe, A.J., and Dean, P. (2010) The EspF effector - a bacterial pathogen's Swiss army knife. Infection and Immunity, 78 (11). pp. 4445-4453. ISSN 0019-9567 (doi:10.1128/IAI.00635-10)

2009

Tree, J.J., Wang, D., McInally, C., Mahajan, A., Layton, A., Houghton, I., Elofsson, M., Stevens, M.P., Gally, D.L., and Roe, A.J. (2009) Characterisation of the effects of salicylidene acylhydrazide compounds on type three secretion in Escherichia coli O157:H7. Infection and Immunity, 77 (10). pp. 4209-4220. ISSN 0019-9567 (doi:10.1128/IAI.00562-09)

Tree, J.J., Wolfson, E.B., Wang, D., Roe, A.J., and Gally, D.L. (2009) Controlling injection: regulation of type III secretion in enterohaemorrhagic Escherichia coli. Trends in Microbiology, 17 (8). pp. 361-370. ISSN 0966-842X (doi:10.1016/j.tim.2009.06.001)

Mahajan, A. et al. (2009) An investigation of the expression and adhesin function of H7 flagella in the interaction of Escherichia coli O157 : H7 with bovine intestinal epithelium. Cellular Microbiology, 11 (1). pp. 121-137. ISSN 1462-5814 (doi:10.1111/j.1462-5822.2008.01244.x)

Mahajan, A. et al. (2009) An investigation of the expression and adhesin function of H7 flagella in the interaction ofEscherichia coliO157 : H7 with bovine intestinal epithelium. Cellular Microbiology, 11 (1). pp. 121-137. ISSN 1462-5814 (doi:10.1111/j.1462-5822.2008.01244.x)

Tree, J. J., Wang, D., McInally, C., Mahajan, A., Layton, A., Houghton, I., Elofsson, M., Stevens, M. P., Gally, D. L., and Roe, A.J. (2009) Characterization of the Effects of Salicylidene Acylhydrazide Compounds on Type III Secretion in Escherichia coli O157:H7. Infection and Immunity, 77 (10). pp. 4209-4220. ISSN 0019-9567 (doi:10.1128/IAI.00562-09)

2008

Wang, D., Roe, A.J., McAteer, S., Shipston, M.J., and Gally, D.L. (2008) Hierarchal type III secretion of translocators and effectors fromEscherichia coliO157:H7 requires the carboxy terminus of SepL that binds to Tir. Molecular Microbiology, 69 (6). pp. 1499-1512. ISSN 0950-382X (doi:10.1111/j.1365-2958.2008.06377.x)

2007

Roe, A. J. et al. (2007) Analysis of the expression, regulation and export of NleA-E in Escherichia coli O157: H7. Microbiology, 153 . pp. 1350-1360. ISSN 1350-0872 (doi:10.1099/mic.0.2006/003707-0)

Roe, A. (2007) Increased adherence and actin pedestal formation by dam-deficient enterohemorrhagic Escherichia coli O157:H7. Molecular Microbiology, 63 (5). pp. 1468-1481. (doi:10.1111/j.1365-2958.2007.05602.x)

2006

Low, A. S., Holden, N., Rosser, T., Roe, A. J., Constantinidou, C., Hobman, J. L., Smith, D. G.E., Low, J. C., and Gally, D. L. (2006) Analysis of firnbrial gene clusters and their expression in enterohaernorrhagic Escherichia coli O157 : H7. Environmental Microbiology, 8 (6). pp. 1033-1047. ISSN 1462-2912 (doi:10.1111/j.1462-2920.2006.00995.x)

Spears, K. J., Roe, A., and Gally, D. L. (2006) A comparison of enteropathogenic and enterohaemorrhagic Escherichia coli pathogenesis. FEMS Microbiology Letters, 255 (2). pp. 187-202. ISSN 0378-1097 (doi:10.1111/j.1574-6968.2006.00119.x)

Roe, A. (2006) Enhancement of bacterial competitive fitness by apramycin resistance plasmids from non-pathogenic Escherichia coli. Biology Letters, 2 (3). pp. 463-465. (doi:10.1098/rsbl.2006.0478)

Roe, A. (2006) Generation of gene deletions and gene replacements in Escherichia coli O157:H7 using a temperature sensitive allelic exchange system. Biological Procedures Online, 8 (1). pp. 153-162. (doi:10.1251/bpo123)

Roe, A. (2006) Demonstration of regulatory cross-talk between P fimbriae and type 1 fimbriae in uropathogenic Escherichia coli. Microbiology: SGM, 152 (Pt4). pp. 1143-1153. ISSN 1350-0872 (doi:10.1099/mic.0.28677-0)

2005

Naylor, S. A., Roe, A. J., Nart, P., Spears, K., Smith, D. G.E., Low, J. C., and Gally, D. L. (2005) Escherichia coli O157 : H7 forms attaching and effacing lesions at the terminal rectum of cattle and colonization requires the LEE4 operon. Microbiology, 151 (8). pp. 2773-2781. ISSN 1350-0872 (doi:10.1099/mic.0.28060-0)

Roe, A. (2005) Type III secretion of the Salmonella effector protein SopE is mediated via an n-terminal amino acid signal and not an mRNA sequence (vol 187, pg 1559, 2005). Journal of Bacteriology, 187 (15). p. 5505. (doi:10.1128/JB.187.15.5505.2005)

2004

Porter, M. E., Mitchell, P., Roe, A. J., Free, A., Smith, D. G.E., and Gally, D. L. (2004) Direct and indirect transcriptional activation of virulence genes by an AraC-like protein, PerA from enteropathogenic Escherichia coli. Molecular Microbiology, 54 (4). pp. 1117-1133. ISSN 0950-382X (doi:10.1111/j.1365-2958.2004.04333.x)

Roe, A. J. et al. (2004) Co-ordinate single-cell expression of LEE4- and LEE5-encoded proteins of Escherichia coli O157:H7. Molecular Microbiology, 54 (2). pp. 337-352. ISSN 0950-382X (doi:10.1111/j.1365-2958.2004.04277.x)

Roe, A. (2004) Co-ordinate single-cell expression of LEE4- and LEE5-encoded proteins of Escherichia coli O157 : H7. Molecular Microbiology, 54 (2). pp. 337-352. (doi:10.1111/j.1365-2958.2004.04277.x)

Roe, A. (2004) Mutation of toxB and a truncated version of the efa-1 gene in Escherichia coli O157 : H7 influences the expression and secretion of locus of enterocyte effacement-encoded proteins but not intestinal colonization in calves or sheep. Infection and Immunity, 72 (9). pp. 5402-5411. (doi:10.1128/IAI.72.9.5402-5411.2004)

Zhang, L. et al. (2004) Regulators encoded in the Escherichia coli type III secretion system 2 gene cluster influence expression of genes within the locus for enterocyte effacement in enterohemorrhagic E. coli 0157 : H7. Infection and Immunity, 72 . pp. 7282-7293. ISSN 0019-9567 (doi:10.1128/IAI.72.12.7282-7293.2004)

2003

Roe, A. J., Yull, H., Naylor, S. W., Woodward, M. J., Smith, D. G.E., and Gally, D. L. (2003) Heterogeneous surface expression of EspA translocon filaments by Escherichia coli O157:H7 is controlled at the posttranscriptional level. Infection and Immunity, 71 (10). pp. 5900-5909. ISSN 0019-9567 (doi:10.1128/IAI.71.10.5900-5909.2003)

Roe, A. (2003) Heterogeneous surface expression of EspA translocon filaments by Escherichia coli O157 : H7 is controlled at the posttranscriptional level. Infection and Immunity, 71 (10). pp. 5900-5909. (doi:10.1128/IAI.71.10.5900-5909.2003)

Roe, A. (2003) Regulation, secretion and activity of type III-secreted proteins of enterohaemorrhagic Escherichia coli O157. Biochemical Society Transactions, 31 (Pt 1). pp. 98-103.

2002

Roe, A. (2002) Inhibition of Escherichia coli growth by acetic acid: a problem with methionine biosynthesis and homocysteine toxicity. Microbiology: SGM, 148 (Pt 7). pp. 2215-2222. ISSN 1350-0872

2001

McNally, A., Roe, A. J., Simpson, S., Thomson-Carter, F. M., Hoey, D.E. E., Currie, C., Chakraborty, T., Smith, D. G.E., and Gally, D. L. (2001) Differences in levels of secreted locus of enterocyte effacement proteins between human disease-associated and bovine Escherichia coli O157. Infection and Immunity, 69 (8). pp. 5107-5114. ISSN 0019-9567 (doi:10.1128/IAI.69.8.5107-5114.2001)

Roe, A. J., Currie, C., Smith, D. G.E., and Gally, D. L. (2001) Analysis of type 1 fimbriae expression in verotoxigenic Escherichia coli: a comparison between serotypes O157 and O26. Microbiology, 147 (Pt 1). pp. 145-52. ISSN 1350-0872

Roe, A. (2001) Analysis of type 1 fimbriae expression in verotoxigenic Escherichia coli: a comparison between serotypes O157 and O26. Microbiology: SGM, 147 (Pt1). pp. 145-152. ISSN 1350-0872

This list was generated on Fri Oct 24 05:25:49 2014 BST.
Jump to: Article
Number of items: 50.

Article

Beckham, K. S.H., and Roe, A. J. (2014) From screen to target: insights and approaches for the development of anti-virulence compounds. Frontiers in Cellular and Infection Microbiology, 4 (139). ISSN 2235-2988 (doi:10.3389/fcimb.2014.00139)

Beckham, K. S.H. et al. (2014) The metabolic enzyme AdhE controls the virulence of Escherichia coli O157:H7. Molecular Microbiology, 93 (1). pp. 199-211. ISSN 0950-382X (doi:10.1111/mmi.12651)

Dunne, K.A. et al. (2013) Increased S-nitrosylation and proteasomal degradation of caspase-3 during infection contribute to the persistence of adherent invasive escherichia coli (AIEC) in immune cells. PLoS ONE, 8 (7). e68386. ISSN 1932-6203 (doi:10.1371/journal.pone.0068386)

Gabrielsen, M., Roe, A.J., and McLuskey, K. (2013) High-throughput methods for the detection of protein overexpression using fluorescence markers. Methods in Cell Biology, 113 . pp. 189-208. ISSN 0091-679X (doi:10.1016/B978-0-12-407239-8.00010-0)

Othman, S., Roe, A.J., Parton, R., and Coote, J.G. (2013) Use of a dual reporter plasmid to demonstrate bactofection with an attenuated aroa- derivative of Pasteurella multocida b:2. PLoS ONE, 8 (8). e71524. ISSN 1932-6203 (doi:10.1371/journal.pone.0071524)

Tahoun, A. et al. (2012) Salmonella transforms follicle-associated epithelial cells into M cells to promote intestinal invasion. Cell Host and Microbe, 12 (5). pp. 645-656. ISSN 1931-3128 (doi:10.1016/j.chom.2012.10.009)

Gabrielsen, M., Rey-Burusco, M.F., Griffiths, K., Roe, A.J., Cooper, A., Smith, B.O., Kennedy, M.W., and Corsico, B. (2012) Two crystal forms of a helix-rich fatty acid- and retinol-binding protein, Na-FAR-1, from the parasitic nematodeNecator americanus. Acta Crystallographica. Section F: Structural Biology and Crystallization Communications, 68 (7). pp. 835-838. ISSN 1744-3091 (doi:10.1107/S1744309112023597)

Beckham, K.S.H., Byron, O., Roe, A.J., and Gabrielsen, M. (2012) The structure of an orthorhombic crystal form of a 'forced reduced' thiol peroxidase reveals lattice formation aided by the presence of the affinity tag. Acta Crystallographica. Section F: Structural Biology and Crystallization Communications, 68 (5). pp. 522-526. ISSN 1744-3091 (doi:10.1107/S1744309112011487)

Beckham, K.S., Byron, O., Roe, A.J., and Gabrielsen, M. (2012) The structure of an orthorhombic crystal form of a `forced reduced' thiol peroxidase reveals lattice formation aided by the presence of the affinity tag. Acta Crystallographica. Section F: Structural Biology and Crystallization Communications, 68 (5). pp. 522-526. ISSN 1744-3091 (doi:10.1107/S1744309112011487)

Christie, J.M., Gawthorne, J., Young, G., Fraser, N.J., and Roe, A.J. (2012) LOV to BLUF: flavoprotein contributions to the optogenetic toolkit. Molecular Plant . ISSN 1674-2052 (doi:10.1093/mp/sss020)

Gabrielsen, M., Beckham, K.S., Feher, V.A., Zetterstrom, C.E., Wang, D., Muller, S., Elofsson, M., Amaro, R.E., Byron, O., and Roe, A.J. (2012) Structural characterisation of Tpx from yersinia pseudotuberculosis reveals insights into the binding of salicylidene acylhydrazide compounds. PLoS ONE, 7 (2). e32217. ISSN 1932-6203 (doi:10.1371/journal.pone.0032217)

Gabrielsen, M., Beckham, K.S.H., Cogdell, R.J., Byron, O., and Roe, A.J. (2012) FolX from Pseudomonas aeruginosa is octameric in both crystal and solution. FEBS Letters, 586 (8). pp. 1160-1165. ISSN 0014-5793 (doi:10.1016/j.febslet.2012.03.031)

Gabrielsen, M., Beckham, K.S.H., and Roe, A.J. (2012) High-throughput methods for the identification of protein purification conditions using a cleavable tag system. Methods in Cell Biology, 112 . pp. 93-110. ISSN 0091-679X (doi:10.1016/B978-0-12-405914-6.00005-6)

Gabrielsen, M., Riboldi-Tunnicliffe, A., Ibáñez-Shimabukuro, M., Griffiths, K., Roe, A.J., Cooper, A., Smith, B., Córsico, B., and Kennedy, M.W. (2012) Useable diffraction data from a multiple microdomain-containing crystal of Ascaris suum As-p18 fatty-acid-binding protein using a microfocus beamline. Acta Crystallographica. Section F: Structural Biology and Crystallization Communications, 68 . pp. 939-941. ISSN 1744-3091 (doi:10.1107/S1744309112026553)

Gabrielsen, M., Riboldi-Tunnicliffe, A., Ibáñez-Shimabukuro, M., Griffiths, K., Roe, A.J., Cooper, A., Smith, B.O., Córsico, B., and Kennedy, M.W. (2012) Useable diffraction data from a multiple microdomain-containing crystal ofAscaris suumAs-p18 fatty-acid-binding protein using a microfocus beamline. Acta Crystallographica. Section F: Structural Biology and Crystallization Communications, 68 (8). pp. 939-941. ISSN 1744-3091 (doi:10.1107/S1744309112026553)

Gawthorne, J.A., Reddick, L.E., Akpunarlieva, S.N., Beckham, K.S.H., Christie, J.M., Alto, N.M., Gabrielsen, M., and Roe, A.J. (2012) Express your LOV: an engineered flavoprotein as a reporter for protein expression and purification. PLoS ONE, 7 (12). e52962. ISSN 1932-6203 (doi:10.1371/journal.pone.0052962)

Schmidt, E.E., Holmes, A., Lindestam Arlehamn, C.S., Wang, D., Mitchell, T.J., Evans, T.J., and Roe, A.J. (2012) Expression and regulation of the Escherichia coli O157:H7 effector proteins NleH1 and NleH2. PLoS ONE, 7 (3). e33408. ISSN 1932-6203 (doi:10.1371/journal.pone.0033408)

Xuefang, X. et al. (2012) Lysogeny with Shiga toxin 2-encoding bacteriophages represses type III secretion in enterohemorrhagic Escherichia coli. PLoS Pathogens, 8 (5). e1002672. ISSN 1553-7366 (doi:10.1371/journal.ppat.1002672)

Gabrielsen, M., Kroner, F., Black, I., Isaacs, N.W., Roe, A.J., and McLuskey, K. (2011) High-throughput identification of purification conditions leads to preliminary crystallization conditions for three inner membrane proteins. Molecular Membrane Biology, 28 (7-8). pp. 445-453. ISSN 0968-7688 (doi:10.3109/09687688.2011.628954)

Wang, D. et al. (2011) Identification of bacterial target proteins for the salicylidene acylhydrazide class of virulence blocking compounds. Journal of Biological Chemistry, 286 (34). pp. 29922-29931. ISSN 0021-9258 (doi:10.1074/jbc.M111.233858)

Tree, J.J. et al. (2011) Transcriptional regulators of the GAD acid stress island are carried by effector protein-encoding prophages and indirectly control type III secretion in enterohemorrhagic Escherichia coli O157:H7. Molecular Microbiology, 80 (5). pp. 1349-1365. ISSN 0950-382X (doi:10.1111/j.1365-2958.2011.07650.x)

Gabrielsen, M., Zetterström, C.E., Wang, D., Beckham, K.S.H., Elofsson, M., Isaacs, N.W., and Roe, A. (2010) Expression, purification, crystallization and initial X-ray diffraction analysis of thiol peroxidase from Yersinia pseudotuberculosis. Acta Crystallographica. Section F: Structural Biology and Crystallization Communications, 66 (12). pp. 1606-1609. ISSN 1744-3091 (doi:10.1107/S1744309110039679)

Holmes, A., Muhlen, S., Roe, A.J., and Dean, P. (2010) The EspF effector - a bacterial pathogen's Swiss army knife. Infection and Immunity, 78 (11). pp. 4445-4453. ISSN 0019-9567 (doi:10.1128/IAI.00635-10)

Tree, J.J., Wang, D., McInally, C., Mahajan, A., Layton, A., Houghton, I., Elofsson, M., Stevens, M.P., Gally, D.L., and Roe, A.J. (2009) Characterisation of the effects of salicylidene acylhydrazide compounds on type three secretion in Escherichia coli O157:H7. Infection and Immunity, 77 (10). pp. 4209-4220. ISSN 0019-9567 (doi:10.1128/IAI.00562-09)

Tree, J.J., Wolfson, E.B., Wang, D., Roe, A.J., and Gally, D.L. (2009) Controlling injection: regulation of type III secretion in enterohaemorrhagic Escherichia coli. Trends in Microbiology, 17 (8). pp. 361-370. ISSN 0966-842X (doi:10.1016/j.tim.2009.06.001)

Mahajan, A. et al. (2009) An investigation of the expression and adhesin function of H7 flagella in the interaction of Escherichia coli O157 : H7 with bovine intestinal epithelium. Cellular Microbiology, 11 (1). pp. 121-137. ISSN 1462-5814 (doi:10.1111/j.1462-5822.2008.01244.x)

Mahajan, A. et al. (2009) An investigation of the expression and adhesin function of H7 flagella in the interaction ofEscherichia coliO157 : H7 with bovine intestinal epithelium. Cellular Microbiology, 11 (1). pp. 121-137. ISSN 1462-5814 (doi:10.1111/j.1462-5822.2008.01244.x)

Tree, J. J., Wang, D., McInally, C., Mahajan, A., Layton, A., Houghton, I., Elofsson, M., Stevens, M. P., Gally, D. L., and Roe, A.J. (2009) Characterization of the Effects of Salicylidene Acylhydrazide Compounds on Type III Secretion in Escherichia coli O157:H7. Infection and Immunity, 77 (10). pp. 4209-4220. ISSN 0019-9567 (doi:10.1128/IAI.00562-09)

Wang, D., Roe, A.J., McAteer, S., Shipston, M.J., and Gally, D.L. (2008) Hierarchal type III secretion of translocators and effectors fromEscherichia coliO157:H7 requires the carboxy terminus of SepL that binds to Tir. Molecular Microbiology, 69 (6). pp. 1499-1512. ISSN 0950-382X (doi:10.1111/j.1365-2958.2008.06377.x)

Roe, A. J. et al. (2007) Analysis of the expression, regulation and export of NleA-E in Escherichia coli O157: H7. Microbiology, 153 . pp. 1350-1360. ISSN 1350-0872 (doi:10.1099/mic.0.2006/003707-0)

Roe, A. (2007) Increased adherence and actin pedestal formation by dam-deficient enterohemorrhagic Escherichia coli O157:H7. Molecular Microbiology, 63 (5). pp. 1468-1481. (doi:10.1111/j.1365-2958.2007.05602.x)

Low, A. S., Holden, N., Rosser, T., Roe, A. J., Constantinidou, C., Hobman, J. L., Smith, D. G.E., Low, J. C., and Gally, D. L. (2006) Analysis of firnbrial gene clusters and their expression in enterohaernorrhagic Escherichia coli O157 : H7. Environmental Microbiology, 8 (6). pp. 1033-1047. ISSN 1462-2912 (doi:10.1111/j.1462-2920.2006.00995.x)

Spears, K. J., Roe, A., and Gally, D. L. (2006) A comparison of enteropathogenic and enterohaemorrhagic Escherichia coli pathogenesis. FEMS Microbiology Letters, 255 (2). pp. 187-202. ISSN 0378-1097 (doi:10.1111/j.1574-6968.2006.00119.x)

Roe, A. (2006) Enhancement of bacterial competitive fitness by apramycin resistance plasmids from non-pathogenic Escherichia coli. Biology Letters, 2 (3). pp. 463-465. (doi:10.1098/rsbl.2006.0478)

Roe, A. (2006) Generation of gene deletions and gene replacements in Escherichia coli O157:H7 using a temperature sensitive allelic exchange system. Biological Procedures Online, 8 (1). pp. 153-162. (doi:10.1251/bpo123)

Roe, A. (2006) Demonstration of regulatory cross-talk between P fimbriae and type 1 fimbriae in uropathogenic Escherichia coli. Microbiology: SGM, 152 (Pt4). pp. 1143-1153. ISSN 1350-0872 (doi:10.1099/mic.0.28677-0)

Naylor, S. A., Roe, A. J., Nart, P., Spears, K., Smith, D. G.E., Low, J. C., and Gally, D. L. (2005) Escherichia coli O157 : H7 forms attaching and effacing lesions at the terminal rectum of cattle and colonization requires the LEE4 operon. Microbiology, 151 (8). pp. 2773-2781. ISSN 1350-0872 (doi:10.1099/mic.0.28060-0)

Roe, A. (2005) Type III secretion of the Salmonella effector protein SopE is mediated via an n-terminal amino acid signal and not an mRNA sequence (vol 187, pg 1559, 2005). Journal of Bacteriology, 187 (15). p. 5505. (doi:10.1128/JB.187.15.5505.2005)

Porter, M. E., Mitchell, P., Roe, A. J., Free, A., Smith, D. G.E., and Gally, D. L. (2004) Direct and indirect transcriptional activation of virulence genes by an AraC-like protein, PerA from enteropathogenic Escherichia coli. Molecular Microbiology, 54 (4). pp. 1117-1133. ISSN 0950-382X (doi:10.1111/j.1365-2958.2004.04333.x)

Roe, A. J. et al. (2004) Co-ordinate single-cell expression of LEE4- and LEE5-encoded proteins of Escherichia coli O157:H7. Molecular Microbiology, 54 (2). pp. 337-352. ISSN 0950-382X (doi:10.1111/j.1365-2958.2004.04277.x)

Roe, A. (2004) Co-ordinate single-cell expression of LEE4- and LEE5-encoded proteins of Escherichia coli O157 : H7. Molecular Microbiology, 54 (2). pp. 337-352. (doi:10.1111/j.1365-2958.2004.04277.x)

Roe, A. (2004) Mutation of toxB and a truncated version of the efa-1 gene in Escherichia coli O157 : H7 influences the expression and secretion of locus of enterocyte effacement-encoded proteins but not intestinal colonization in calves or sheep. Infection and Immunity, 72 (9). pp. 5402-5411. (doi:10.1128/IAI.72.9.5402-5411.2004)

Zhang, L. et al. (2004) Regulators encoded in the Escherichia coli type III secretion system 2 gene cluster influence expression of genes within the locus for enterocyte effacement in enterohemorrhagic E. coli 0157 : H7. Infection and Immunity, 72 . pp. 7282-7293. ISSN 0019-9567 (doi:10.1128/IAI.72.12.7282-7293.2004)

Roe, A. J., Yull, H., Naylor, S. W., Woodward, M. J., Smith, D. G.E., and Gally, D. L. (2003) Heterogeneous surface expression of EspA translocon filaments by Escherichia coli O157:H7 is controlled at the posttranscriptional level. Infection and Immunity, 71 (10). pp. 5900-5909. ISSN 0019-9567 (doi:10.1128/IAI.71.10.5900-5909.2003)

Roe, A. (2003) Heterogeneous surface expression of EspA translocon filaments by Escherichia coli O157 : H7 is controlled at the posttranscriptional level. Infection and Immunity, 71 (10). pp. 5900-5909. (doi:10.1128/IAI.71.10.5900-5909.2003)

Roe, A. (2003) Regulation, secretion and activity of type III-secreted proteins of enterohaemorrhagic Escherichia coli O157. Biochemical Society Transactions, 31 (Pt 1). pp. 98-103.

Roe, A. (2002) Inhibition of Escherichia coli growth by acetic acid: a problem with methionine biosynthesis and homocysteine toxicity. Microbiology: SGM, 148 (Pt 7). pp. 2215-2222. ISSN 1350-0872

McNally, A., Roe, A. J., Simpson, S., Thomson-Carter, F. M., Hoey, D.E. E., Currie, C., Chakraborty, T., Smith, D. G.E., and Gally, D. L. (2001) Differences in levels of secreted locus of enterocyte effacement proteins between human disease-associated and bovine Escherichia coli O157. Infection and Immunity, 69 (8). pp. 5107-5114. ISSN 0019-9567 (doi:10.1128/IAI.69.8.5107-5114.2001)

Roe, A. J., Currie, C., Smith, D. G.E., and Gally, D. L. (2001) Analysis of type 1 fimbriae expression in verotoxigenic Escherichia coli: a comparison between serotypes O157 and O26. Microbiology, 147 (Pt 1). pp. 145-52. ISSN 1350-0872

Roe, A. (2001) Analysis of type 1 fimbriae expression in verotoxigenic Escherichia coli: a comparison between serotypes O157 and O26. Microbiology: SGM, 147 (Pt1). pp. 145-152. ISSN 1350-0872

This list was generated on Fri Oct 24 05:25:49 2014 BST.