Dr Bill Mullen

  • Senior Research Fellow (Institute of Cardiovascular and Medical Sciences)
  • Associate - Life Sciences (School of Life Sciences)

telephone: 01413306210
email: William.Mullen@glasgow.ac.uk

Research interests

Bill Mullen is a Research Fellow for the Institute of Cardiovascular & Medical Sciences at the University of Glasgow. He returned to the University after working in a Pharmaceutical Drug Metabolism lab and also running his own company designing and manufacturing scientific instruments for metabolite analysis. Since returning to the University in 1998 he has published more than 60 manuscripts in peer reviewed journals. His first 10 years back at the University was in the Plant Products and Human Nutrition group, where his expertise in mass spectrometric analysis became world renowned. His principle aim was to find causal links between diet and health. We all know that a diet rich in fruit and vegetables is good for us, but why? It became apparent to him that the classical bioavailability/ metabolism approach to this question was not going to reveal the answer. The chance to work with Harald Mischak in applied systems biology, with the latest Orbitrap mass spectrometer, was too good an offer to turn down. Although the primary goal of the group is generating peptide “fingerprints” of disease to allow early diagnosis and monitoring of treatment, this work would lend itself to his original question of why fruit and vegetables are needed for a healthy life. By being able to determine deterioration in health as such an early stage, that no lasting damage had incurred, he believes it may be possible to show changes in diet could alter the biomarker fingerprints from unhealthy to healthy.

Grants

Grants and Awards listed are those received whilst working with the University of Glasgow.

  • Metabolite and protein profiling in CADASIL to unravel the vascular pathophysiology and natural history
    NHS Endowment Funds
    2014 - 2016
     
  • SysVasc
    European Commission
    2014 - 2018
     
  • Urine proteomics as biomarker for inflammatory arthritis
    Pfizer Global Research and Development
    2013 - 2014
     
  • Can a football-based weight management, physical activity and healthy living programme be adapted for delivery in secure institutional settings to support at risk groups in positive, sustainable ....
    Scottish Executive Health Department
    2013 - 2015
     
  • Bioavailability of Olive Oil phenolics and impact of high olive oil consumption on proteomic markers
    University of Lisbon
    2012 - 2015
     
  • The iomarkers in Stroke Programme; Detecting, Understanding, and Predicting Outcome After Stroke (ISSF Catalyst Fund)
    Wellcome Trust
    2011 - 2014
     
  • Investigating the potential of cathepsin-L as a common therapeutic target and biomarker for coronary heart disease and African trypanosomiasis (ISSF Catalyst Fund)
    Wellcome Trust
    2011 - 2014
     

Publications

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Jump to: 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006
Number of items: 80.

2015

Pontillo, C., Filip, S., Borràs, D. M., Mullen, W., Vlahou, A., and Mischak, H. (2015) CE-MS-based proteomics in biomarker discovery and clinical application. Proteomics Clinical Applications, 9(3-4), pp. 322-334. (doi:10.1002/prca.201400115) (PMID:25641774)

Kuhla, B., Laeger, T., Husi, H., and Mullen, W. (2015) Cerebrospinal fluid prohormone processing and neuropeptides stimulating feed intake of dairy cows during early lactation. Journal of Proteome Research, 14(2), pp. 823-828. (doi:10.1021/pr500872k) (PMID:25547169)

Brown, C. E. et al. (2015) Urinary proteomic biomarkers to predict cardiovascular events. Proteomics Clinical Applications, (doi:10.1002/prca.201400195) (PMID:25786980) (Early Online Publication)

Stalmach, A., Husi, H., Mosbahi, K., Albalat, A., Mullen, W., and Mischak, H. (2015) Methods in capillary electrophoresis coupled to mass spectrometry for the identification of clinical proteomic/peptidomic biomarkers in biofluids. Methods in Molecular Biology, 1243, pp. 187-205. (doi:10.1007/978-1-4939-1872-0_11)

2014

Seetho, I. W. et al. (2014) Urinary proteomics in obstructive sleep apnoea and obesity. European Journal of Clinical Investigation, 44(11), pp. 1104-1115. (doi:10.1111/eci.12346) (PMID:25267120)

Siwy, J. et al. (2014) Multicentre prospective validation of a urinary peptidome-based classifier for the diagnosis of type 2 diabetic nephropathy. Nephrology, Dialysis, Transplantation, 29(8), pp. 1563-1570. (doi:10.1093/ndt/gfu039)

Husi, H., Van Agtmael, T., Mullen, W., Bahlmann, F. H., Schanstra, J. P., Vlahou, A., Delles, C., Perco, P., and Mischak, H. (2014) Proteome-based systems biology analysis of the diabetic mouse aorta reveals major changes in fatty acid biosynthesis as potential hallmark in diabetes mellitus-associated vascular disease. Circulation: Cardiovascular Genetics, 7(2), pp. 161-170. (doi:10.1161/CIRCGENETICS.113.000196)

Klein, J., Papadopoulos, T., Mischak, H., and Mullen, W. (2014) Comparison of CE-MS/MS and LC-MS/MS sequencing demonstrates significant complementarity in natural peptide identification in human urine. Electrophoresis, 35(7), pp. 1060-1064. (doi:10.1002/elps.201300327)

Mullen, W., Saigusa, D., Abe, T., Adamski, J., and Mischak, H. (2014) Proteomics and metabolomics as tools to unravel novel culprits and mechanisms of uremic toxicity: instrument or hype? Seminars in Nephrology, 34(2), pp. 180-190. (doi:10.1016/j.semnephrol.2014.02.009)

Frantzi, M. et al. (2014) Discovery and validation of urinary biomarkers for detection of renal cell carcinoma. Journal of Proteomics, 98C, pp. 44-58. (doi:10.1016/j.jprot.2013.12.010)

Klein, J., Buffin-Meyer, B., Mullen, W., Carty, D. M., Delles, C., Vlahou, A., Mischak, H., Decramer, S., Bascands, J.-L., and Schanstra, J. P. (2014) Clinical proteomics in obstetrics and neonatology. Expert Review of Proteomics, 11(1), pp. 75-89. (doi:10.1586/14789450.2014.872564)

Silva, S., Bronze, M. R., Figueira, M. E., Siwy, J., Mischak, H., Combet, E., and Mullen, W. (2014) Impact of a 6-wk olive oil supplementation in healthy adults on urinary proteomic biomarkers of coronary artery disease, chronic kidney disease, and diabetes (types 1 and 2): a randomized, parallel, controlled, double-blind study. American Journal of Clinical Nutrition, 101(4), pp. 44-54. (doi:10.3945/ajcn.114.094219)

Albalat, A., Husi, H., Siwy, J., Nally, J.E., McLaughlin, M., Eckersall, P.D., and Mullen, W. (2014) Capillary electrophoresis interfaced with a mass spectrometer (CE-MS): technical considerations and applicability for biomarker studies in animals. Current Protein and Peptide Science, 15(1), pp. 23-35. (doi:10.2174/1389203715666140221123920)

Koss, M. J. et al. (2014) Proteomics of vitreous humor of patients with exudative age-related macular degeneration. PLoS ONE, 9(5), e96895. (doi:10.1371/journal.pone.0096895)

Latosinska, A., Frantzi, M., Mullen, W., Vlahou, A., and Makridakis, M. (2014) Targeting the proteome of cellular fractions: focus on secreted proteins. Methods in Molecular Biology, 1243, pp. 29-41. (doi:10.1007/978-1-4939-1872-0_2)

Nkuipou-Kenfack, E. et al. (2014) Assessment of metabolomic and proteomic biomarkers in detection and prognosis of progression of renal function in chronic kidney disease. PLoS ONE, 9(5), e96955. (doi:10.1371/journal.pone.0096955)

Stalmach, A., Johnsson, H., McInnes, I. B., Husi, H., Klein, J., Dakna, M., Mullen, W., Mischak, H., and Porter, D. (2014) Identification of urinary peptide biomarkers associated with rheumatoid arthritis. PLoS ONE, 9(8), e104625. (doi:10.1371/journal.pone.0104625)

Tedesco, S., Mullen, W., and Cristobal, S. (2014) High-throughput proteomics: a new tool for quality and safety in fishery products. Current Protein and Peptide Science, 15(2), pp. 118-133. (doi:10.2174/1389203715666140221120219)

Weissinger, E. M., Mullen, W., and Albalat, A. (2014) Urinary proteomics employing capillary electrophoresis coupled to mass spectrometry in the monitoring of patients after stem cell transplantation. Methods in Molecular Biology, 1109, pp. 293-306. (doi:10.1007/978-1-4614-9437-9_15)

2013

Frantzi, M. et al. (2013) IMAC fractionation in combination with LC–MS reveals H2B and NIF-1 peptides as potential bladder cancer biomarkers. Journal of Proteome Research, 12(9), pp. 3969-3979. (doi:10.1021/pr400255h)

Klein, J. et al. (2013) Fetal urinary peptides to predict postnatal outcome of renal disease in fetuses with posterior urethral valves(PUV). Science Translational Medicine, 5(198), 198ra106. (doi:10.1126/scitranslmed.3005807)

Mansor, R., Mullen, W., Albalat, A., Zerefos, P., Mischak, H., Barrett, D.C., Biggs, A., and Eckersall, P.D. (2013) A peptidomic approach to biomarker discovery for bovine mastitis. Journal of Proteomics, 85, pp. 89-98. (doi:10.1016/j.jprot.2013.04.027)

Stalmach, A., Albalat, A., Mullen, W., and Mischak, H. (2013) Recent advances in capillary electrophoresis coupled to mass spectrometry for clinical proteomic applications. Electrophoresis, 34(11), pp. 1452-1464. (doi:10.1002/elps.201200708)

Dissard, R. et al. (2013) Long term metabolic syndrome induced by a high fat high fructose diet leads to minimal renal injury in C57BL/6 mice. PLoS ONE, 8(10), e76703. (doi:10.1371/journal.pone.0076703)

Husi, H., Sanchez-Niño, M., Delles, C., Mullen, W., Vlahou, A., Ortiz, A., and Mischak, H. (2013) A combinatorial approach of Proteomics and Systems Biology in unravelling the mechanisms of acute kidney injury (AKI): involvement of NMDA receptor GRIN1 in murine AKI. BMC Systems Biology, 7(110), (doi:10.1186/1752-0509-7-110)

Kistler, A.D. et al. (2013) Urinary proteomic biomarkers for diagnosis and risk stratification of autosomal dominant polycystic kidney disease: a multicentric study. PLoS ONE, 8(1), e53016. (doi:10.1371/journal.pone.0053016)

Metzger, J. et al. (2013) Urine proteomic analysis differentiates cholangiocarcinoma from primary sclerosing cholangitis and other benign biliary disorders. Gut, 62(1), pp. 122-130. (doi:10.1136/gutjnl-2012-302047)

Mullen, W., Nemzer, B., Stalmach, A., Sidrah, A., and Combet, E. (2013) The polyphenolic and hydroxycinnamate contents of whole coffee fruits from China, India and Mexico. Journal of Agricultural and Food Chemistry, 61(22), pp. 5298-5309. (doi:10.1021/jf4003126)

Weissinger, E.M. et al. (2013) Proteomic peptide profiling for preemptive diagnosis of acute graft-versus-host-disease after allogeneic stem cell transplantation. Leukemia, (doi:10.1038/leu.2013.210)

2012

Mullen, W. (2012) The human urinary proteome: combinational approaches to comprehensive mapping. Expert Review of Proteomics, 9(4), pp. 375-377. (doi:10.1586/epr.12.36)

Mullen, W., Albalat, A., Gonzalez, J., Zerefos, P., Siwy, J., Franke, J., and Mischak, H. (2012) Performance of different separation methods interfaced in the same MS-reflection TOF detector: a comparison of performance between CE versus HPLC for biomarker analysis. Electrophoresis, 33(4), pp. 567-574. (doi:10.1002/elps.201100415)

Dawson, J., Walters, M., Delles, C., Mischak, H., and Mullen, W. (2012) Urinary proteomics to support diagnosis of stroke. PLoS ONE, 7(5), e35879. (doi:10.1371/journal.pone.0035879)

Kitson, S.M., Mullen, W., Cogdell, R.J., Bill, R.M., and Fraser, N.J. (2012) GPCR production in a novel yeast strain that makes cholesterol-like sterols. Methods, 55(4), pp. 287-292. (doi:10.1016/j.ymeth.2011.09.023)

Kuznetsova, T., Mischak, H., Mullen, W., and Staessen, J.A. (2012) Urinary proteome analysis in hypertensive patients with left ventricular diastolic dysfunction. European Heart Journal, 33(18), pp. 2342-2350. (doi:10.1093/eurheartj/ehs185)

Mullen, W., Gonzalez, J., Siwy, J., Franke, J., Sattar, N., Mullan, A., Roberts, S., Delles, C., Mischak, H., and Albalat, A. (2012) A pilot study on the effect of short-term consumption of a polyphenol rich drink on biomarkers of coronary artery disease defined by urinary proteomics. Journal of Agricultural and Food Chemistry, 59(24), pp. 12850-12857. (doi:10.1021/jf203369r)

Omar, M.H., Mullen, W., Stalmach, A., Auger, C., Rouanet, J.-M., Teissedre, P.-L., Caldwell, S.T., Hartley, R.C., and Crozier, A. (2012) Absorption, disposition, metabolism, and excretion of [3-14C]caffeic acid in rats. Journal of Agricultural and Food Chemistry, 60(20), pp. 5205-5214. (doi:10.1021/jf3001185)

Rouse, R., Siwy, J., Mullen, W., Mischak, H., Metzger, J., and Hanig, J. (2012) Proteomic candidate biomarkers of drug-induced nephrotoxicity in the rat. PLoS ONE, 7(4), e34606. (doi:10.1371/journal.pone.0034606)

Siwy, J. et al. (2012) Evaluation of the zucker diabetic fatty (ZDF) rat as a model for human disease based on urinary peptidomic profiles. PLoS ONE, 7(12), e51334. (doi:10.1371/journal.pone.0051334)

2011

Albalat, A., Mischak, H., and Mullen, W. (2011) Urine proteomics in clinical applications: technologies, principal considerations and clinical implementation. Prilozi, 32(1), pp. 13-44.

AlGamdi, N., Mullen, W., and Crozier, A. (2011) Tea prepared from Anastatica hirerochuntica seeds contains a diversity of antioxidant flavonoids, chlorogenic acids and phenolic compounds. Phytochemistry, 72(2-3), pp. 248-254. (doi:10.1016/j.phytochem.2010.11.017)

Lopez, L.M., Mullen, W., Zürbig, P., Harris, S.E., Gow, A.J., Starr, J.M., Porteous, D.J., Mischak, H., and Deary, I.J. (2011) A pilot study of urinary peptides as biomarkers for intelligence in old age. Intelligence, 39(1), pp. 46-53. (doi:10.1016/j.intell.2010.11.001)

Albalat, A., Gornik, S.G., Mullen, W., Crozier, A., Atkinson, R.J.A., Coombs, G.H., and Neil, D.M. (2011) Quality changes in chilled Norway lobster (Nephrops norvegicus) tail meat and the effects of delayed icing. International Journal of Food Science and Technology, 46(7), pp. 1413-1421. (doi:10.1111/j.1365-2621.2011.02650.x)

Albalat, A., Mischak, H., and Mullen, W. (2011) Clinical application of urinary proteomics/peptidomics. Expert Review of Proteomics, 8(5), pp. 615-629. (doi:10.1586/epr.11.46)

Carty, D.M. et al. (2011) Urinary proteomics for prediction of preeclampsia. Hypertension, 57(3), pp. 561-569. (doi:10.1161/HYPERTENSIONAHA.110.164285)

Kistler, A.D. et al. (2011) A distinct urinary biomarker pattern characteristic of female fabry patients that mirrors response to enzyme replacement therapy. PLoS ONE, 6(6), e20534. (doi:10.1371/journal.pone.0020534)

Metzger, J. et al. (2011) Diagnosis of subclinical and clinical acute T-cell-mediated rejection in renal transplant patients by urinary proteome analysis. Proteomics Clinical Applications, 5(5-6), pp. 322-333. (doi:10.1002/prca.201000153)

Mullen, W., Delles, C., and Mischak, H. (2011) Urinary proteomics in the assessment of chronic kidney disease. Current Opinion in Nephrology and Hypertension, 20(6), pp. 654-661. (doi:10.1097/MNH.0b013e32834b7ffa)

Mullen, W., Nemzer, B., Ou, B., Stalmach, A., Hunter, J., Clifford, M.N., and Combet, E. (2011) The antioxidant and chlorogenic acid profiles of whole coffee fruits are influenced by the extraction procedures. Journal of Agricultural and Food Chemistry, 59(8), pp. 3754-3762. (doi:10.1021/jf200122m)

Omar, M.H., Mullen, W., and Crozier, A. (2011) Identification of proanthocyanidin dimers and trimers, FlavoneC-Glycosides, and antioxidants in Ficus deltoidea, a Malaysian herbal tea. Journal of Agricultural and Food Chemistry, 59(4), pp. 1363-1369. (doi:10.1021/jf1032729)

Siwy, J., Mullen, W., Golovko, I., Franke, J., and Zürbig, P. (2011) Human urinary peptide database for multiple disease biomarker discovery. Proteomics Clinical Applications, 5(5-6), pp. 367-374. (doi:10.1002/prca.201000155)

Wittke, S., Jahn, H., Z, P., Kellmann, M., Mullen, W., Eichenlaub, M., and Mischak, H. (2011) Peptide fingerprinting of Alzheimer's disease in cerebrospinal fluid: identification and prospective evaluation of new synaptic biomarkers. PLoS ONE, 6(10), e26540. (doi:10.1371/journal.pone.0026540)

2010

Borges, G., Mullen, W., and Crozier, A. (2010) Comparison of the polyphenolic composition and antioxidant activity of European commercial fruit juices. Food and Function, 1(1), pp. 73-83. (doi:10.1039/c0fo00008f)

Borges, G., Mullen, W., Mullan, A., Lean, M., Roberts, S., and Crozier, A. (2010) Bioavailability of multiple components following acute ingestion of a polyphenol-rich juice drink. Molecular Nutrition and Food Research, 54(S2), S268-S277. (doi:10.1002/mnfr.200900611)

Borges, G., Degeneve, A., Mullen, W., and Crozier, A. (2010) Identification of flavonoid and phenolic antioxidants in black currants, blueberries, raspberries, red currants, and cranberries. Journal of Agricultural and Food Chemistry, 58(7), pp. 3901-3909. (doi:10.1021/jf902263n)

Ashihara, H., Deng, W.-W., Mullen, W., and Crozier, A. (2010) Distribution and biosynthesis of flavan-3-ols in Camellia sinensis seedlings and expression of genes encoding biosynthetic enzymes. Phytochemistry, 71(5-6), pp. 559-566. (doi:10.1016/j.phytochem.2010.01.010)

Stalmach, A., Mullen, W., Steiling, H., Williamson, G., Lean, M.E.J., and Crozier, A. (2010) Absorption, metabolism, and excretion of green tea flavan-3-ols in humans with an ileostomy. Molecular Nutrition and Food Research, 54(3), pp. 323-334. (doi:10.1002/mnfr.200900194)

Gonzalez-Barrio, R., Borges, G., Mullen, W., and Crozier, A. (2010) Bioavailability of Anthocyanins and Ellagitannins Following Consumption of Raspberries by Healthy Humans and Subjects with an Ileostomy. Journal of Agricultural and Food Chemistry, 58(7), pp. 3933-3939. (doi:10.1021/jf100315d)

González-Barrio, R., Borges, G., Mullen, W., and Crozier, A. (2010) Bioavailability of Anthocyanins and Ellagitannins Following Consumption of Raspberries by Healthy Humans and Subjects with an Ileostomy†. Journal of Agricultural and Food Chemistry, 58(7), pp. 3933-3939. (doi:10.1021/jf100315d)

Larcombe, S.D., Mullen, W., Alexander, L., and Arnold, K.E. (2010) Dietary antioxidants, lipid peroxidation and plumage colouration in nestling blue tits Cyanistes caeruleus. Naturwissenschaften, 97(10), pp. 903-913. (doi:10.1007/s00114-010-0708-5)

Mullen, W., Borges, G., Lean, M.E.J., Roberts, S.A., and Crozier, A. (2010) Identification of metabolites in human plasma and urine after consumption of a polyphenol-rich juice drink. Journal of Agricultural and Food Chemistry, 58(4), pp. 2586-2595. (doi:10.1021/jf904096v)

Mullen, W., Larcombe, S., Arnold, K., Welchman, H., and Crozier, A. (2010) Use of accurate mass full scan mass spectrometry for the analysis of anthocyanins in berries and berry-fed tissues. Journal of Agricultural and Food Chemistry, 58(7), pp. 3910-3915. (doi:10.1021/jf902267v)

Roowi, S., Stalmach, A., Mullen, W., Lean, M., Edwards, C.A., and Crozier, A. (2010) Green tea flavan-3-ols: colonic degradation and urinary excretion of catabolites by humans. Journal of Agricultural and Food Chemistry, 58(2), pp. 1296-1304. (doi:10.1021/jf9032975)

Troufflard, S., Mullen, W., Larson, T. R., Graham, I. A., Crozier, A., Amtmann, A., and Armengaud, P. (2010) Potassium deficiency induces the biosynthesis of oxylipins and glucosinolates in Arabidopsis thaliana. BMC Plant Biology, 10(1), p. 172. (doi:10.1186/1471-2229-10-172)

Wright, B., Moraes, L.A., Kemp, C.F., Mullen, W., Crozier, A., Lovegrove, J.A., and Gibbins, J.M. (2010) A structural basis for the inhibition of collagen-stimulated platelet function by quercetin and structurally related flavonoids. British Journal of Pharmacology, 159(6), pp. 1312-1325. (doi:10.1111/j.1476-5381.2009.00632.x)

2009

Jaganath, I.B., Mullen, W., Lean, M., Edwards, C.A., and Crozier, A. (2009) In vitro catabolism of rutin by human fecal bacteria and the antioxidant capacity of its catabolites. Free Radical Biology and Medicine, 47(8), pp. 1180-1189. (doi:10.1016/j.freeradbiomed.2009.07.031)

Stalmach, A., Mullen, W., Barron, D., Uchida, K., Yokota, T., Cavin, C., Steiling, H., Williamson, G., and Crozier, A. (2009) Metabolite profiling of hydroxycinnamate derivatives in plasma and urine after the ingestion of coffee by humans: identification of biomarkers of coffee consumption. Drug Metabolism and Disposition, 37(8), pp. 1749-1758. (doi:10.1124/dmd.109.028019)

Mullen, W., Borges, G.,, Donovan, J.L., Edwards, C.A., Serafini, M., Lean, M.E.J., and Crozier, A. (2009) Milk decreases urinary excretion but not plasma pharmacokinetics of cocoa flavan-3-ol metabolites in humans. American Journal of Clinical Nutrition, 89(6), pp. 1784-1791. (doi:10.3945/ajcn.2008.27339)

Marks, S.C., Mullen, W., Borges, G., and Crozier, A. (2009) Absorption, Metabolism, and Excretion of Cider Dihydrochalcones in Healthy Humans and Subjects with an Ileostomy. Journal of Agricultural and Food Chemistry, 57(5), pp. 2009-2015. (doi:10.1021/jf802757x)

Renouf, M. et al. (2009) Metabolism of chlorogenic acids after coffee ingestion in ileostomy and healthy subjects. In: 22nd International Conference on Coffee Science, ASIC 2008, Campinas, Brazil, 14-19 September 2008, pp. 110-117.

Roowi, S., Mullen, W., Edwards, C.A., and Crozier, A. (2009) Yoghurt impacts on the excretion of phenolic acids derived from colonic breakdown of orange juice flavanones in humans. Molecular Nutrition and Food Research, 53(Suppl ), S68-S75. (doi:10.1002/mnfr.200800287)

Stalmach, A., Mullen, W., Pecorari, M., Serafini, M., and Crozier, A. (2009) Bioavailability of c-linked dihydrochalcone and flavanone glucosides in humans following ingestion of unfermented and fermented rooibos teas. Journal of Agricultural and Food Chemistry, 57(15), pp. 7104-7111. (doi:10.1021/jf9011642)

2008

Jordão, A.M., Ricardo-Da-Silva, J.M., Laureano, O., Mullen, W., and Crozier, A. (2008) Effect of ellagitannins, ellagic acid and volatile compounds from oak wood on the (+)-catechin, procyanidin B1 and malvidin-3-glucoside content of model wines. Australian Journal of Grape and Wine Research, 14(3), pp. 260-270.

Auger, C., Mullen, W., Hara, Y., and Crozier, A. (2008) Bioavailability of polyphenon E flavan-3-ols in humans with an lleostomy. Journal of Nutrition, 138(8), 1535S-1542S.

Gauliard, B., Grieve, D., Wilson, R., Crozier, A., Jenkins, C., Mullen, W., and Lean, M. (2008) The effects of dietary phenolic compounds on cytokine and antioxidant production by a549 cells. Journal of Medicinal Food, 11(2), pp. 382-384. (doi:10.1089/jmf.2007.593)

Mullen, W., Archeveque, M.-A., Edwards, C.A., Matsumoto, H., and Crozier, A. (2008) Bioavailability and Metabolism of Orange Juice Flavanones in Humans: Impact of a Full-Fat Yogurt. Journal of Agricultural and Food Chemistry, 56(23), pp. 11157-11164. (doi:10.1021/jf801974v)

Mullen, W., Edwards, C.A., Serafini, M., and Crozier, A. (2008) Bioavailability of pelargonidin-3-O-glucoside and its metabolites in humans following the ingestion of strawberries with and without cream. Journal of Agricultural and Food Chemistry, 56(3), pp. 713-719. (doi:10.1021/jf072000p)

Mullen, W., Rouanet, J.-M., Auger, C., Teissèdre, P.-L., Caldwell, S.T., Hartley, R.C., Lean, M.E.J., Edwards, C.A., and Crozier, A. (2008) Bioavailability of [2-14C]Quercetin-4′-glucoside in rats. Journal of Agricultural and Food Chemistry, 56(24), pp. 12127-12137. (doi:10.1021/jf802754s)

2007

Combet, E., Paterson, S., Iijima, K., Winter, J., Mullen, W., Crozier, A., Preston, T., and McColl, K.E.L. (2007) Fat transforms ascorbic acid from inhibiting to promoting acid-catalysed N-nitrosation. Gut, 56, pp. 1678-1684. (doi:10.1136/gut.2007.128587)

Marks, S.C., Mullen, W., and Crozier, A. (2007) Flavonoid and hydroxycinnamate profiles of English apple ciders. Journal of Agricultural and Food Chemistry, 55, pp. 8723-8730. (doi:10.1021/jf071155u)

2006

Stalmach, A., Mullen, W., Nagai, A., and Crozier, A. (2006) On-line HPLC analysis of the antioxidant activity of phenolic compounds in brewed, paper-filtered coffee. Brazilian Journal of Plant Physiology, 18(1), pp. 253-262. (doi:10.1590/S1677-04202006000100018)

This list was generated on Mon May 25 07:31:08 2015 BST.
Number of items: 80.

Articles

Pontillo, C., Filip, S., Borràs, D. M., Mullen, W., Vlahou, A., and Mischak, H. (2015) CE-MS-based proteomics in biomarker discovery and clinical application. Proteomics Clinical Applications, 9(3-4), pp. 322-334. (doi:10.1002/prca.201400115) (PMID:25641774)

Kuhla, B., Laeger, T., Husi, H., and Mullen, W. (2015) Cerebrospinal fluid prohormone processing and neuropeptides stimulating feed intake of dairy cows during early lactation. Journal of Proteome Research, 14(2), pp. 823-828. (doi:10.1021/pr500872k) (PMID:25547169)

Brown, C. E. et al. (2015) Urinary proteomic biomarkers to predict cardiovascular events. Proteomics Clinical Applications, (doi:10.1002/prca.201400195) (PMID:25786980) (Early Online Publication)

Stalmach, A., Husi, H., Mosbahi, K., Albalat, A., Mullen, W., and Mischak, H. (2015) Methods in capillary electrophoresis coupled to mass spectrometry for the identification of clinical proteomic/peptidomic biomarkers in biofluids. Methods in Molecular Biology, 1243, pp. 187-205. (doi:10.1007/978-1-4939-1872-0_11)

Seetho, I. W. et al. (2014) Urinary proteomics in obstructive sleep apnoea and obesity. European Journal of Clinical Investigation, 44(11), pp. 1104-1115. (doi:10.1111/eci.12346) (PMID:25267120)

Siwy, J. et al. (2014) Multicentre prospective validation of a urinary peptidome-based classifier for the diagnosis of type 2 diabetic nephropathy. Nephrology, Dialysis, Transplantation, 29(8), pp. 1563-1570. (doi:10.1093/ndt/gfu039)

Husi, H., Van Agtmael, T., Mullen, W., Bahlmann, F. H., Schanstra, J. P., Vlahou, A., Delles, C., Perco, P., and Mischak, H. (2014) Proteome-based systems biology analysis of the diabetic mouse aorta reveals major changes in fatty acid biosynthesis as potential hallmark in diabetes mellitus-associated vascular disease. Circulation: Cardiovascular Genetics, 7(2), pp. 161-170. (doi:10.1161/CIRCGENETICS.113.000196)

Klein, J., Papadopoulos, T., Mischak, H., and Mullen, W. (2014) Comparison of CE-MS/MS and LC-MS/MS sequencing demonstrates significant complementarity in natural peptide identification in human urine. Electrophoresis, 35(7), pp. 1060-1064. (doi:10.1002/elps.201300327)

Mullen, W., Saigusa, D., Abe, T., Adamski, J., and Mischak, H. (2014) Proteomics and metabolomics as tools to unravel novel culprits and mechanisms of uremic toxicity: instrument or hype? Seminars in Nephrology, 34(2), pp. 180-190. (doi:10.1016/j.semnephrol.2014.02.009)

Frantzi, M. et al. (2014) Discovery and validation of urinary biomarkers for detection of renal cell carcinoma. Journal of Proteomics, 98C, pp. 44-58. (doi:10.1016/j.jprot.2013.12.010)

Klein, J., Buffin-Meyer, B., Mullen, W., Carty, D. M., Delles, C., Vlahou, A., Mischak, H., Decramer, S., Bascands, J.-L., and Schanstra, J. P. (2014) Clinical proteomics in obstetrics and neonatology. Expert Review of Proteomics, 11(1), pp. 75-89. (doi:10.1586/14789450.2014.872564)

Silva, S., Bronze, M. R., Figueira, M. E., Siwy, J., Mischak, H., Combet, E., and Mullen, W. (2014) Impact of a 6-wk olive oil supplementation in healthy adults on urinary proteomic biomarkers of coronary artery disease, chronic kidney disease, and diabetes (types 1 and 2): a randomized, parallel, controlled, double-blind study. American Journal of Clinical Nutrition, 101(4), pp. 44-54. (doi:10.3945/ajcn.114.094219)

Albalat, A., Husi, H., Siwy, J., Nally, J.E., McLaughlin, M., Eckersall, P.D., and Mullen, W. (2014) Capillary electrophoresis interfaced with a mass spectrometer (CE-MS): technical considerations and applicability for biomarker studies in animals. Current Protein and Peptide Science, 15(1), pp. 23-35. (doi:10.2174/1389203715666140221123920)

Koss, M. J. et al. (2014) Proteomics of vitreous humor of patients with exudative age-related macular degeneration. PLoS ONE, 9(5), e96895. (doi:10.1371/journal.pone.0096895)

Latosinska, A., Frantzi, M., Mullen, W., Vlahou, A., and Makridakis, M. (2014) Targeting the proteome of cellular fractions: focus on secreted proteins. Methods in Molecular Biology, 1243, pp. 29-41. (doi:10.1007/978-1-4939-1872-0_2)

Nkuipou-Kenfack, E. et al. (2014) Assessment of metabolomic and proteomic biomarkers in detection and prognosis of progression of renal function in chronic kidney disease. PLoS ONE, 9(5), e96955. (doi:10.1371/journal.pone.0096955)

Stalmach, A., Johnsson, H., McInnes, I. B., Husi, H., Klein, J., Dakna, M., Mullen, W., Mischak, H., and Porter, D. (2014) Identification of urinary peptide biomarkers associated with rheumatoid arthritis. PLoS ONE, 9(8), e104625. (doi:10.1371/journal.pone.0104625)

Tedesco, S., Mullen, W., and Cristobal, S. (2014) High-throughput proteomics: a new tool for quality and safety in fishery products. Current Protein and Peptide Science, 15(2), pp. 118-133. (doi:10.2174/1389203715666140221120219)

Weissinger, E. M., Mullen, W., and Albalat, A. (2014) Urinary proteomics employing capillary electrophoresis coupled to mass spectrometry in the monitoring of patients after stem cell transplantation. Methods in Molecular Biology, 1109, pp. 293-306. (doi:10.1007/978-1-4614-9437-9_15)

Frantzi, M. et al. (2013) IMAC fractionation in combination with LC–MS reveals H2B and NIF-1 peptides as potential bladder cancer biomarkers. Journal of Proteome Research, 12(9), pp. 3969-3979. (doi:10.1021/pr400255h)

Klein, J. et al. (2013) Fetal urinary peptides to predict postnatal outcome of renal disease in fetuses with posterior urethral valves(PUV). Science Translational Medicine, 5(198), 198ra106. (doi:10.1126/scitranslmed.3005807)

Mansor, R., Mullen, W., Albalat, A., Zerefos, P., Mischak, H., Barrett, D.C., Biggs, A., and Eckersall, P.D. (2013) A peptidomic approach to biomarker discovery for bovine mastitis. Journal of Proteomics, 85, pp. 89-98. (doi:10.1016/j.jprot.2013.04.027)

Stalmach, A., Albalat, A., Mullen, W., and Mischak, H. (2013) Recent advances in capillary electrophoresis coupled to mass spectrometry for clinical proteomic applications. Electrophoresis, 34(11), pp. 1452-1464. (doi:10.1002/elps.201200708)

Dissard, R. et al. (2013) Long term metabolic syndrome induced by a high fat high fructose diet leads to minimal renal injury in C57BL/6 mice. PLoS ONE, 8(10), e76703. (doi:10.1371/journal.pone.0076703)

Husi, H., Sanchez-Niño, M., Delles, C., Mullen, W., Vlahou, A., Ortiz, A., and Mischak, H. (2013) A combinatorial approach of Proteomics and Systems Biology in unravelling the mechanisms of acute kidney injury (AKI): involvement of NMDA receptor GRIN1 in murine AKI. BMC Systems Biology, 7(110), (doi:10.1186/1752-0509-7-110)

Kistler, A.D. et al. (2013) Urinary proteomic biomarkers for diagnosis and risk stratification of autosomal dominant polycystic kidney disease: a multicentric study. PLoS ONE, 8(1), e53016. (doi:10.1371/journal.pone.0053016)

Metzger, J. et al. (2013) Urine proteomic analysis differentiates cholangiocarcinoma from primary sclerosing cholangitis and other benign biliary disorders. Gut, 62(1), pp. 122-130. (doi:10.1136/gutjnl-2012-302047)

Mullen, W., Nemzer, B., Stalmach, A., Sidrah, A., and Combet, E. (2013) The polyphenolic and hydroxycinnamate contents of whole coffee fruits from China, India and Mexico. Journal of Agricultural and Food Chemistry, 61(22), pp. 5298-5309. (doi:10.1021/jf4003126)

Weissinger, E.M. et al. (2013) Proteomic peptide profiling for preemptive diagnosis of acute graft-versus-host-disease after allogeneic stem cell transplantation. Leukemia, (doi:10.1038/leu.2013.210)

Mullen, W. (2012) The human urinary proteome: combinational approaches to comprehensive mapping. Expert Review of Proteomics, 9(4), pp. 375-377. (doi:10.1586/epr.12.36)

Mullen, W., Albalat, A., Gonzalez, J., Zerefos, P., Siwy, J., Franke, J., and Mischak, H. (2012) Performance of different separation methods interfaced in the same MS-reflection TOF detector: a comparison of performance between CE versus HPLC for biomarker analysis. Electrophoresis, 33(4), pp. 567-574. (doi:10.1002/elps.201100415)

Dawson, J., Walters, M., Delles, C., Mischak, H., and Mullen, W. (2012) Urinary proteomics to support diagnosis of stroke. PLoS ONE, 7(5), e35879. (doi:10.1371/journal.pone.0035879)

Kitson, S.M., Mullen, W., Cogdell, R.J., Bill, R.M., and Fraser, N.J. (2012) GPCR production in a novel yeast strain that makes cholesterol-like sterols. Methods, 55(4), pp. 287-292. (doi:10.1016/j.ymeth.2011.09.023)

Kuznetsova, T., Mischak, H., Mullen, W., and Staessen, J.A. (2012) Urinary proteome analysis in hypertensive patients with left ventricular diastolic dysfunction. European Heart Journal, 33(18), pp. 2342-2350. (doi:10.1093/eurheartj/ehs185)

Mullen, W., Gonzalez, J., Siwy, J., Franke, J., Sattar, N., Mullan, A., Roberts, S., Delles, C., Mischak, H., and Albalat, A. (2012) A pilot study on the effect of short-term consumption of a polyphenol rich drink on biomarkers of coronary artery disease defined by urinary proteomics. Journal of Agricultural and Food Chemistry, 59(24), pp. 12850-12857. (doi:10.1021/jf203369r)

Omar, M.H., Mullen, W., Stalmach, A., Auger, C., Rouanet, J.-M., Teissedre, P.-L., Caldwell, S.T., Hartley, R.C., and Crozier, A. (2012) Absorption, disposition, metabolism, and excretion of [3-14C]caffeic acid in rats. Journal of Agricultural and Food Chemistry, 60(20), pp. 5205-5214. (doi:10.1021/jf3001185)

Rouse, R., Siwy, J., Mullen, W., Mischak, H., Metzger, J., and Hanig, J. (2012) Proteomic candidate biomarkers of drug-induced nephrotoxicity in the rat. PLoS ONE, 7(4), e34606. (doi:10.1371/journal.pone.0034606)

Siwy, J. et al. (2012) Evaluation of the zucker diabetic fatty (ZDF) rat as a model for human disease based on urinary peptidomic profiles. PLoS ONE, 7(12), e51334. (doi:10.1371/journal.pone.0051334)

Albalat, A., Mischak, H., and Mullen, W. (2011) Urine proteomics in clinical applications: technologies, principal considerations and clinical implementation. Prilozi, 32(1), pp. 13-44.

AlGamdi, N., Mullen, W., and Crozier, A. (2011) Tea prepared from Anastatica hirerochuntica seeds contains a diversity of antioxidant flavonoids, chlorogenic acids and phenolic compounds. Phytochemistry, 72(2-3), pp. 248-254. (doi:10.1016/j.phytochem.2010.11.017)

Lopez, L.M., Mullen, W., Zürbig, P., Harris, S.E., Gow, A.J., Starr, J.M., Porteous, D.J., Mischak, H., and Deary, I.J. (2011) A pilot study of urinary peptides as biomarkers for intelligence in old age. Intelligence, 39(1), pp. 46-53. (doi:10.1016/j.intell.2010.11.001)

Albalat, A., Gornik, S.G., Mullen, W., Crozier, A., Atkinson, R.J.A., Coombs, G.H., and Neil, D.M. (2011) Quality changes in chilled Norway lobster (Nephrops norvegicus) tail meat and the effects of delayed icing. International Journal of Food Science and Technology, 46(7), pp. 1413-1421. (doi:10.1111/j.1365-2621.2011.02650.x)

Albalat, A., Mischak, H., and Mullen, W. (2011) Clinical application of urinary proteomics/peptidomics. Expert Review of Proteomics, 8(5), pp. 615-629. (doi:10.1586/epr.11.46)

Carty, D.M. et al. (2011) Urinary proteomics for prediction of preeclampsia. Hypertension, 57(3), pp. 561-569. (doi:10.1161/HYPERTENSIONAHA.110.164285)

Kistler, A.D. et al. (2011) A distinct urinary biomarker pattern characteristic of female fabry patients that mirrors response to enzyme replacement therapy. PLoS ONE, 6(6), e20534. (doi:10.1371/journal.pone.0020534)

Metzger, J. et al. (2011) Diagnosis of subclinical and clinical acute T-cell-mediated rejection in renal transplant patients by urinary proteome analysis. Proteomics Clinical Applications, 5(5-6), pp. 322-333. (doi:10.1002/prca.201000153)

Mullen, W., Delles, C., and Mischak, H. (2011) Urinary proteomics in the assessment of chronic kidney disease. Current Opinion in Nephrology and Hypertension, 20(6), pp. 654-661. (doi:10.1097/MNH.0b013e32834b7ffa)

Mullen, W., Nemzer, B., Ou, B., Stalmach, A., Hunter, J., Clifford, M.N., and Combet, E. (2011) The antioxidant and chlorogenic acid profiles of whole coffee fruits are influenced by the extraction procedures. Journal of Agricultural and Food Chemistry, 59(8), pp. 3754-3762. (doi:10.1021/jf200122m)

Omar, M.H., Mullen, W., and Crozier, A. (2011) Identification of proanthocyanidin dimers and trimers, FlavoneC-Glycosides, and antioxidants in Ficus deltoidea, a Malaysian herbal tea. Journal of Agricultural and Food Chemistry, 59(4), pp. 1363-1369. (doi:10.1021/jf1032729)

Siwy, J., Mullen, W., Golovko, I., Franke, J., and Zürbig, P. (2011) Human urinary peptide database for multiple disease biomarker discovery. Proteomics Clinical Applications, 5(5-6), pp. 367-374. (doi:10.1002/prca.201000155)

Wittke, S., Jahn, H., Z, P., Kellmann, M., Mullen, W., Eichenlaub, M., and Mischak, H. (2011) Peptide fingerprinting of Alzheimer's disease in cerebrospinal fluid: identification and prospective evaluation of new synaptic biomarkers. PLoS ONE, 6(10), e26540. (doi:10.1371/journal.pone.0026540)

Borges, G., Mullen, W., and Crozier, A. (2010) Comparison of the polyphenolic composition and antioxidant activity of European commercial fruit juices. Food and Function, 1(1), pp. 73-83. (doi:10.1039/c0fo00008f)

Borges, G., Mullen, W., Mullan, A., Lean, M., Roberts, S., and Crozier, A. (2010) Bioavailability of multiple components following acute ingestion of a polyphenol-rich juice drink. Molecular Nutrition and Food Research, 54(S2), S268-S277. (doi:10.1002/mnfr.200900611)

Borges, G., Degeneve, A., Mullen, W., and Crozier, A. (2010) Identification of flavonoid and phenolic antioxidants in black currants, blueberries, raspberries, red currants, and cranberries. Journal of Agricultural and Food Chemistry, 58(7), pp. 3901-3909. (doi:10.1021/jf902263n)

Ashihara, H., Deng, W.-W., Mullen, W., and Crozier, A. (2010) Distribution and biosynthesis of flavan-3-ols in Camellia sinensis seedlings and expression of genes encoding biosynthetic enzymes. Phytochemistry, 71(5-6), pp. 559-566. (doi:10.1016/j.phytochem.2010.01.010)

Stalmach, A., Mullen, W., Steiling, H., Williamson, G., Lean, M.E.J., and Crozier, A. (2010) Absorption, metabolism, and excretion of green tea flavan-3-ols in humans with an ileostomy. Molecular Nutrition and Food Research, 54(3), pp. 323-334. (doi:10.1002/mnfr.200900194)

Gonzalez-Barrio, R., Borges, G., Mullen, W., and Crozier, A. (2010) Bioavailability of Anthocyanins and Ellagitannins Following Consumption of Raspberries by Healthy Humans and Subjects with an Ileostomy. Journal of Agricultural and Food Chemistry, 58(7), pp. 3933-3939. (doi:10.1021/jf100315d)

González-Barrio, R., Borges, G., Mullen, W., and Crozier, A. (2010) Bioavailability of Anthocyanins and Ellagitannins Following Consumption of Raspberries by Healthy Humans and Subjects with an Ileostomy†. Journal of Agricultural and Food Chemistry, 58(7), pp. 3933-3939. (doi:10.1021/jf100315d)

Larcombe, S.D., Mullen, W., Alexander, L., and Arnold, K.E. (2010) Dietary antioxidants, lipid peroxidation and plumage colouration in nestling blue tits Cyanistes caeruleus. Naturwissenschaften, 97(10), pp. 903-913. (doi:10.1007/s00114-010-0708-5)

Mullen, W., Borges, G., Lean, M.E.J., Roberts, S.A., and Crozier, A. (2010) Identification of metabolites in human plasma and urine after consumption of a polyphenol-rich juice drink. Journal of Agricultural and Food Chemistry, 58(4), pp. 2586-2595. (doi:10.1021/jf904096v)

Mullen, W., Larcombe, S., Arnold, K., Welchman, H., and Crozier, A. (2010) Use of accurate mass full scan mass spectrometry for the analysis of anthocyanins in berries and berry-fed tissues. Journal of Agricultural and Food Chemistry, 58(7), pp. 3910-3915. (doi:10.1021/jf902267v)

Roowi, S., Stalmach, A., Mullen, W., Lean, M., Edwards, C.A., and Crozier, A. (2010) Green tea flavan-3-ols: colonic degradation and urinary excretion of catabolites by humans. Journal of Agricultural and Food Chemistry, 58(2), pp. 1296-1304. (doi:10.1021/jf9032975)

Troufflard, S., Mullen, W., Larson, T. R., Graham, I. A., Crozier, A., Amtmann, A., and Armengaud, P. (2010) Potassium deficiency induces the biosynthesis of oxylipins and glucosinolates in Arabidopsis thaliana. BMC Plant Biology, 10(1), p. 172. (doi:10.1186/1471-2229-10-172)

Wright, B., Moraes, L.A., Kemp, C.F., Mullen, W., Crozier, A., Lovegrove, J.A., and Gibbins, J.M. (2010) A structural basis for the inhibition of collagen-stimulated platelet function by quercetin and structurally related flavonoids. British Journal of Pharmacology, 159(6), pp. 1312-1325. (doi:10.1111/j.1476-5381.2009.00632.x)

Jaganath, I.B., Mullen, W., Lean, M., Edwards, C.A., and Crozier, A. (2009) In vitro catabolism of rutin by human fecal bacteria and the antioxidant capacity of its catabolites. Free Radical Biology and Medicine, 47(8), pp. 1180-1189. (doi:10.1016/j.freeradbiomed.2009.07.031)

Stalmach, A., Mullen, W., Barron, D., Uchida, K., Yokota, T., Cavin, C., Steiling, H., Williamson, G., and Crozier, A. (2009) Metabolite profiling of hydroxycinnamate derivatives in plasma and urine after the ingestion of coffee by humans: identification of biomarkers of coffee consumption. Drug Metabolism and Disposition, 37(8), pp. 1749-1758. (doi:10.1124/dmd.109.028019)

Mullen, W., Borges, G.,, Donovan, J.L., Edwards, C.A., Serafini, M., Lean, M.E.J., and Crozier, A. (2009) Milk decreases urinary excretion but not plasma pharmacokinetics of cocoa flavan-3-ol metabolites in humans. American Journal of Clinical Nutrition, 89(6), pp. 1784-1791. (doi:10.3945/ajcn.2008.27339)

Marks, S.C., Mullen, W., Borges, G., and Crozier, A. (2009) Absorption, Metabolism, and Excretion of Cider Dihydrochalcones in Healthy Humans and Subjects with an Ileostomy. Journal of Agricultural and Food Chemistry, 57(5), pp. 2009-2015. (doi:10.1021/jf802757x)

Roowi, S., Mullen, W., Edwards, C.A., and Crozier, A. (2009) Yoghurt impacts on the excretion of phenolic acids derived from colonic breakdown of orange juice flavanones in humans. Molecular Nutrition and Food Research, 53(Suppl ), S68-S75. (doi:10.1002/mnfr.200800287)

Stalmach, A., Mullen, W., Pecorari, M., Serafini, M., and Crozier, A. (2009) Bioavailability of c-linked dihydrochalcone and flavanone glucosides in humans following ingestion of unfermented and fermented rooibos teas. Journal of Agricultural and Food Chemistry, 57(15), pp. 7104-7111. (doi:10.1021/jf9011642)

Jordão, A.M., Ricardo-Da-Silva, J.M., Laureano, O., Mullen, W., and Crozier, A. (2008) Effect of ellagitannins, ellagic acid and volatile compounds from oak wood on the (+)-catechin, procyanidin B1 and malvidin-3-glucoside content of model wines. Australian Journal of Grape and Wine Research, 14(3), pp. 260-270.

Auger, C., Mullen, W., Hara, Y., and Crozier, A. (2008) Bioavailability of polyphenon E flavan-3-ols in humans with an lleostomy. Journal of Nutrition, 138(8), 1535S-1542S.

Gauliard, B., Grieve, D., Wilson, R., Crozier, A., Jenkins, C., Mullen, W., and Lean, M. (2008) The effects of dietary phenolic compounds on cytokine and antioxidant production by a549 cells. Journal of Medicinal Food, 11(2), pp. 382-384. (doi:10.1089/jmf.2007.593)

Mullen, W., Archeveque, M.-A., Edwards, C.A., Matsumoto, H., and Crozier, A. (2008) Bioavailability and Metabolism of Orange Juice Flavanones in Humans: Impact of a Full-Fat Yogurt. Journal of Agricultural and Food Chemistry, 56(23), pp. 11157-11164. (doi:10.1021/jf801974v)

Mullen, W., Edwards, C.A., Serafini, M., and Crozier, A. (2008) Bioavailability of pelargonidin-3-O-glucoside and its metabolites in humans following the ingestion of strawberries with and without cream. Journal of Agricultural and Food Chemistry, 56(3), pp. 713-719. (doi:10.1021/jf072000p)

Mullen, W., Rouanet, J.-M., Auger, C., Teissèdre, P.-L., Caldwell, S.T., Hartley, R.C., Lean, M.E.J., Edwards, C.A., and Crozier, A. (2008) Bioavailability of [2-14C]Quercetin-4′-glucoside in rats. Journal of Agricultural and Food Chemistry, 56(24), pp. 12127-12137. (doi:10.1021/jf802754s)

Combet, E., Paterson, S., Iijima, K., Winter, J., Mullen, W., Crozier, A., Preston, T., and McColl, K.E.L. (2007) Fat transforms ascorbic acid from inhibiting to promoting acid-catalysed N-nitrosation. Gut, 56, pp. 1678-1684. (doi:10.1136/gut.2007.128587)

Marks, S.C., Mullen, W., and Crozier, A. (2007) Flavonoid and hydroxycinnamate profiles of English apple ciders. Journal of Agricultural and Food Chemistry, 55, pp. 8723-8730. (doi:10.1021/jf071155u)

Stalmach, A., Mullen, W., Nagai, A., and Crozier, A. (2006) On-line HPLC analysis of the antioxidant activity of phenolic compounds in brewed, paper-filtered coffee. Brazilian Journal of Plant Physiology, 18(1), pp. 253-262. (doi:10.1590/S1677-04202006000100018)

Conference Proceedings

Renouf, M. et al. (2009) Metabolism of chlorogenic acids after coffee ingestion in ileostomy and healthy subjects. In: 22nd International Conference on Coffee Science, ASIC 2008, Campinas, Brazil, 14-19 September 2008, pp. 110-117.

This list was generated on Mon May 25 07:31:08 2015 BST.