Professor Anna Dominiczak

  • Regius Professor of Medicine (Institute of Cardiovascular and Medical Sciences)
  • Vice Principal & Head of College (MVLS College Senior Management)

email: Anna.Dominiczak@glasgow.ac.uk

MVLS College Office
Wolfson Medical School Building
University Avenue
Glasgow G12 8QQ


Professor Anna Dominiczak is Regius Professor of Medicine, Vice Principal and Head of College of Medical, Veterinary and Life Sciences at the University of Glasgow as well as honorary consultant physician with the Greater Glasgow and Clyde Health Board.

A graduate of the Medical School in Gdansk, Poland, Prof Dominiczak, is one of the world’s leading cardiovascular scientists and clinical academics. She held a British Heart Foundation Chair of Cardiovascular Medicine at the University of Glasgow between 1997 and 2010, as well as the directorship of the Cardiovascular Research Centre between 2000 and 2010. Her major research interests are in hypertension, cardiovascular genomics and systems medicine and her total research income in the last three years totals more than £30 million.

Prof Dominiczak is a Fellow of the Royal College of Physicians, the Academy of Medical Sciences, the Royal Society of Edinburgh, the American Heart Association and the European Society of Cardiology as well as a member of the Association of Physicians of Great Britain and Ireland, the European Society of Hypertension, American Physiological Society, Society of Endocrinology, British Hypertension Society and British Cardiovascular Society.

She was a secretary of the Scientific Council of the International Society of Hypertension between 2002 and 2006 and is currently a member at large of the Scientific Council of the European Society of Hypertension, and a member of the Leadership Committee of the Council for High Blood Pressure Research of the American Heart Association.

With more than 250 publications in peer-reviewed journals, in 2005 her services to medicine were recognised by the Queen who awarded her with an OBE.

In addition to membership of several editorial boards, Professor Dominiczak was Editor-in-Chief of Clinical Science between 2004 and 2008, an Associate Editor of the Journal of Hypertension between 2009 and 2011 and Editor-in-Chief of Hypertension as from January 2012.

Her expertise and scientific and clinical contributions are widely recognised with invitations to serve on the Medical Research Council Physiological Medicine Board, British Heart Foundation Project Grant Committee, the Wellcome Trust Physiological Science Committee, the Scientific Advisory Boards of the Leducq Foundation, the Max Dellbrück Centre in Berlin and the George Pompidou European Hospital (HEGP) in Paris.

She has been invited to give over 100 international plenary and state-of-the-art lectures, including the Presidential Award and Lecture of the Canadian Hypertension Society, the Corcoran Award and Lecture of the American Heart Association, R. D. Wright Award and Lecture of the high Blood Pressure Research Council of Australia and the Bjorn Folkow Award and Lecture of the European Society of Hypertension. In 2010 Anna is also a Sackler Lecturer at the Tel Aviv University.

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Number of items: 288.

2014

Arking, D. E. et al. (2014) Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization. Nature Genetics, 46 (8). pp. 826-836. ISSN 1061-4036 (doi:10.1038/ng.3014)

Tragante, V. et al. (2014) Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple blood-pressure-related loci. American Journal of Human Genetics, 94 (3). pp. 349-360. ISSN 0002-9297 (doi:10.1016/j.ajhg.2013.12.016)

Graham, L. A. et al. (2014) Validation of uromodulin as a candidate gene for human essential hypertension. Hypertension, 63 (3). pp. 551-558. ISSN 0194-911X (doi:10.1161/HYPERTENSIONAHA.113.01423)

McLachlan, J., Beattie, E., Murphy, M. P., Koh-Tan, C. H.H., Olson, E., Beattie, W., Dominiczak, A. F., Nicklin, S. A., and Graham, D. (2014) Combined therapeutic benefit of mitochondria-targeted antioxidant, MitoQ10, and angiotensin receptor blocker, losartan, on cardiovascular function. Journal of Hypertension, 32 (3). pp. 555-564. ISSN 0263-6352 (doi:10.1097/HJH.0000000000000054)

Carty, D.M., Neisius, U., Rooney, L., Dominiczak, A., and Delles, C. (2014) Pulse wave analysis for prediction of preeclampsia. Journal of Human Hypertension, 28 (2). pp. 98-104. ISSN 0950-9240 (doi:10.1038/jhh.2013.64)

Carty, D.M., Neisius, U., Rooney, L.K., Dominiczak, A.F., and Delles, C. (2014) Pulse wave analysis for the prediction of preeclampsia. Journal of Human Hypertension, 28 (2). pp. 98-104. ISSN 0950-9240 (doi:10.1038/jhh.2013.64)

Mancia, G. et al. (2014) 2013 ESH/ESC practice guidelines for the management of arterial hypertension. Blood Pressure, 23 (1). pp. 3-16. ISSN 0803-7051 (doi:10.3109/08037051.2014.868629)

Bailey, E. L., McBride, M. W., Crawford, W., McClure, J. D., Graham, D., Dominiczak, A. F., Sudlow, C. L.M., Smith, C., and Wardlaw, J. M. (2014) Differential gene expression in multiple neurological, inflammatory and connective tissue pathways in a spontaneous model of human small vessel stroke. Neuropathology and Applied Neurobiology . ISSN 0305-1846 (doi:10.1111/nan.12116) (Early Online Publication)

Beattie, C. J., Fulton, R. L., Higgins, P., Padmanabhan, S., McCallum, L., Walters, M. R., Dominiczak, A. F., Touyz, R. M., and Dawson, J. (2014) Allopurinol initiation and change in blood pressure in older adults with hypertension. Hypertension . ISSN 0194-911X (doi:10.1161/HYPERTENSIONAHA.114.03953) (Early Online Publication)

Dominiczak, A.F., and Fink, G.D. (2014) Celebrating 35 years of success. Hypertension, 63 (1). pp. 2-3. ISSN 0194-911X (doi:10.1161/HYPERTENSIONAHA.113.02762)

Holmes, M. V. et al. (2014) Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data. BMJ, 349 . g4164. ISSN 1756-1833 (doi:10.1136/bmj.g4164)

Holmes, M. V. et al. (2014) Mendelian randomization of blood lipids for coronary heart disease. European Heart Journal . ISSN 0195-668X (doi:10.1093/eurheartj/eht571)

McCallum, L. et al. (2014) Response to effect of serum chloride on mortality in hypertensive patients. Hypertension, 63 (3). e15-e15. ISSN 0194-911X (doi:10.1161/HYPERTENSIONAHA.113.02926)

Norsworthy, P. J. et al. (2014) Targeted genetic testing for familial hypercholesterolaemia using next generation sequencing: a population-based study. BMC Medical Genetics, 15 (1). p. 70. ISSN 1471-2350 (doi:10.1186/1471-2350-15-70)

Padmanabhan, S., Caulfield, M., and Dominiczak, A. F. (2014) Genetic basis of blood pressure and hypertension. In: Mancia, G., Grassi, G. and Redon, J. (eds.) Manual of Hypertension of the European Society of Hypertension, Second Edition. CRC Press , Boca Raton, FL, pp. 115-128. ISBN 9781841849973

Williamson, C. et al. (2014) Family history of premature cardiovascular disease: blood pressure control and long-term mortality outcomes in hypertensive patients. European Heart Journal, 35 (9). pp. 563-570. ISSN 0195-668X (doi:10.1093/eurheartj/eht539)

Yoneyama, S. et al. (2014) Gene-centric meta-analyses for central adiposity traits in up to 57 412 individuals of European descent confirm known loci and reveal several novel associations. Human Molecular Genetics, 23 (9). pp. 2498-2510. ISSN 0964-6906 (doi:10.1093/hmg/ddt626)

2013

McCallum, L. et al. (2013) Serum chloride is an independent predictor of mortality in hypertensive patients. Hypertension, 62 (5). pp. 836-843. ISSN 0194-911X (doi:10.1161/HYPERTENSIONAHA.113.01793)

Hastie, C., Sloan, W., Dominiczak, A., Morrison, D., and Padmanabhan, S. (2013) Long-term and ultra long-term blood pressure variability during follow-up and mortality in 14 522 patients with hypertension. Hypertension, 62 (4). pp. 698-705. ISSN 0194-911X (doi:10.1161/HYPERTENSIONAHA.113.01343)

Mancia, G. et al. (2013) 2013 practice guidelines for the management of arterial hypertension of the European Society of Hypertension (ESH) and the European Society of Cardiology (ESC). Journal of Hypertension, 31 (10). pp. 1925-1938. ISSN 0263-6352 (doi:10.1097/HJH.0b013e328364ca4c)

Goodson, N.J., Smith, B.H., Hocking, L.J., McGilchrist, M.M., Dominiczak, A.F., Morris, A., Porteous, D.J., and Goebel, A. (2013) Cardiovascular risk factors associated with the metabolic syndrome are more prevalent in people reporting chronic pain: Results from a cross-sectional general population study. Pain, 154 (9). pp. 1595-1602. ISSN 0304-3959 (doi:10.1016/j.pain.2013.04.043)

Rossi, S. H. et al. (2013) Impaired renal function impacts negatively on vascular stiffness in patients with coronary artery disease. BMC Nephrology, 14 (173). ISSN 1471-2369 (doi:10.1186/1471-2369-14-173)

Atanur, S.S. et al. (2013) Genome sequencing reveals loci under artificial selection that underlie disease phenotypes in the laboratory rat. Cell, 154 (3). pp. 691-703. ISSN 0092-8674 (doi:10.1016/j.cell.2013.06.040)

Aubini è re-Robb, L. et al. (2013) Blood pressure response to patterns of weather fluctuations and effect on mortality. Hypertension, 62 (1). pp. 190-196. ISSN 0194-911X (doi:10.1161/HYPERTENSIONAHA.111.00686)

Smith, B. H. et al. (2013) Generation Scotland: Scottish family health study. A profile of the study, its participants, and their potential for genetic research on health and illness. International Journal of Epidemiology, 42 (3). pp. 689-700. ISSN 0300-5771 (doi:10.1093/ije/dys084)

Carty, D.M., Dominiczak, A., and Delles, C. (2013) Pulse wave analysis for prediction of preeclampsia. Endocrine Reviews, 34 (3). SAT-520. ISSN 0163-769X

MacKenzie, R.M. et al. (2013) Mitochondrial reactive oxygen species enhance AMP-activated protein kinase activation in the endothelium of patients with coronary artery disease and diabetes. Clinical Science, 124 (6). pp. 403-411. ISSN 0143-5221 (doi:10.1042/CS20120239)

Alvarez-Madrazo, S. et al. (2013) Common polymorphisms in the CYP11B1 and CYP11B2 genes: evidence for a digenic influence on hypertension. Hypertension, 61 (1). pp. 232-239. ISSN 0194-911X (doi:10.1161/HYPERTENSIONAHA.112.200741)

Baud, A. et al. (2013) Combined sequence-based and genetic mapping analysis of complex traits in outbred rats. Nature Genetics, 45 (7). pp. 767-775. ISSN 1061-4036 (doi:10.1038/ng.2644)

Brittain, J.F. et al. (2013) An MRI-histological study of white matter in stroke-free SHRSP. Journal of Cerebral Blood Flow and Metabolism, 33 (5). pp. 760-763. ISSN 0271-678X (doi:10.1038/jcbfm.2013.14)

Dawson, J. et al. (2013) Acetaminophen use and change in blood pressure in a hypertensive population. Journal of Hypertension, 31 (7). pp. 1485-1490. ISSN 0263-6352 (doi:10.1097/HJH.0b013e328360f6f8)

Dawson, J. et al. (2013) Serum uric acid level, longitudinal blood pressure, renal function, and long-term mortality in treated hypertensive patients. Hypertension, 62 (1). pp. 105-111. ISSN 0194-911X (doi:10.1161/HYPERTENSIONAHA.113.00859)

Dominiczak, A. (2013) Hypertension: update 2013. Hypertension, 61 (1). p. 2. ISSN 0194-911X (doi:10.1161/HYPERTENSIONAHA.111.00667)

Hastie, C. et al. (2013) Long-term and ultra-long term blood pressure variability during follow–up and mortality in 14522 patients with hypertension. Hypertension, 62 (4). pp. 698-705. ISSN 0194-911X (doi:10.1161/HYPERTENSIONAHA.113.01343)

Koh-Tan, H.H. C., McBride, M. W., McClure, J. D., Beattie, E., Young, B., Dominiczak, A. F., and Graham, D. (2013) Interaction between chromosome 2 and 3 regulates pulse pressure in the stroke-prone spontaneously hypertensive rat. Hypertension, 62 (1). pp. 33-40. ISSN 0194-911X (doi:10.1161/HYPERTENSIONAHA.111.00814)

Mancia, G. et al. (2013) 2013 ESH/ESC guidelines for the management of arterial hypertension: the task force for the management of arterial hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). European Heart Journal, 34 (28). pp. 2159-2219. ISSN 0195-668X (doi:10.1093/eurheartj/eht151)

McDonough, C.W., Gong, Y., Padmanabhan, S., Burkley, B., Langaee, T.Y., Melander, O., Pepine, C.J., Dominiczak, A.F., Cooper-DeHoff, R.M., and Johnson, J.A. (2013) Pharmacogenomic association of nonsynonymous SNPs in SIGLEC12, A1BG, and the selectin region and cardiovascular outcomes. Hypertension, 62 (1). pp. 48-54. ISSN 0194-911X (doi:10.1161/HYPERTENSIONAHA.111.00823)

Smith, B.H. et al. (2013) Cohort profile: Generation Scotland: Scottish Family Health Study (GS:SFHS). The study, its participants and their potential for genetic research on health and illness. International Journal of Epidemiology, 42 (3). pp. 689-700. ISSN 0300-5771 (doi:10.1093/ije/dys084)

Turner, S.T. et al. (2013) Genomic association analysis of common variants influencing antihypertensive response to hydrochlorothiazide. Hypertension, 62 . pp. 391-397. ISSN 0194-911X (doi:10.1161/HYPERTENSIONAHA.111.00436)

2012

Sanna-Cherchi, S. et al. (2012) Copy-number disorders are a common cause of congenital kidney malformations. American Journal of Human Genetics, 91 (6). pp. 987-997. ISSN 0002-9297 (doi:10.1016/j.ajhg.2012.10.007)

Mackenzie, R.M., Sandrim, V.C., Carty, D.M., McClure, J.D., Freeman, D.J., Dominiczak, A.F., McBride, M.W., and Delles, C. (2012) Endothelial FOS expression and pre-eclampsia. BJOG: An International Journal of Obstetrics and Gynaecology, 119 (13). pp. 1564-1571. ISSN 1470-0328 (doi:10.1111/1471-0528.12016)

Asselbergs, F.W. et al. (2012) Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. American Journal of Human Genetics, 91 (5). pp. 823-838. ISSN 0002-9297 (doi:10.1016/j.ajhg.2012.08.032)

Paul, L. et al. (2012) Hematocrit predicts long-term mortality in a nonlinear and sex-specific manner in hypertensive adults. Hypertension, 60 (3). pp. 631-638. ISSN 0194-911X (doi:10.1161/HYPERTENSIONAHA.112.191510)

Hocking, L.J. et al. (2012) Heritability of chronic pain in 2195 extended families. European Journal of Pain, 16 (7). pp. 1053-1063. ISSN 1090-3801 (doi:10.1002/j.1532-2149.2011.00095.x)

Carty, D.M., Anderson, L.A., Freeman, D.J., Welsh, P.I., Brennand, J.E., Dominiczak, A.F., and Delles, C. (2012) Early pregnancy soluble E-selectin concentrations and risk of preeclampsia. Journal of Hypertension, 30 (5). pp. 954-959. ISSN 0263-6352 (doi:10.1097/HJH.0b013e328352573b)

Saxena, R. et al. (2012) Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci. American Journal of Human Genetics, 90 (3). pp. 410-425. ISSN 0002-9297 (doi:10.1016/j.ajhg.2011.12.022)

Currie, G., Freel, E. M., Perry, C. G., and Dominiczak, A. F. (2012) Disorders of blood pressure regulation — role of catecholamine biosynthesis, release, and metabolism. Current Hypertension Reports, 14 (1). pp. 38-45. ISSN 1522-6417 (doi:10.1007/s11906-011-0239-2)

Carty, D.M., Anderson, L.A., Duncan, C.N., Baird, D., Rooney, L.K., Dominiczak, A.F., and Delles, C. (2012) Peripheral arterial tone: assessment of microcirculatory function in pregnancy. Journal of Hypertension, 30 (1). pp. 117-123. ISSN 0263-6352 (doi:10.1097/HJH.0b013e32834d76fb)

Charchar, F.J. et al. (2012) Inheritance of coronary artery disease in men: an analysis of the role of the Y chromosome. Lancet, 379 (9819). pp. 915-922. ISSN 0140-6736 (doi:10.1016/S0140-6736(11)61453-0)

Dominiczak, A.F. (2012) Hypertension: update 2012. Hypertension, 59 (4). pp. 753-754. ISSN 0194-911X (doi:10.1161/HYP.0b013e31824f9ffe)

Flores, M., Graham, D., Dominiczak, A.F., Milligan, G., Baker, A.H., and Nicklin, S.A. (2012) Angiotensin-(1-9) antagonises Angiotensin II-induced cardiac remodeling via the angiotensin type 2 receptor. Proceedings of the Physiological Society, 27 . C1. ISSN 1749-6187

Flores, M., Work, L.M., Douglas, K., Denby, L., Dominiczak, A.F., Graham, D., and Nicklin, S.A. (2012) Angiotensin-(1-9) attenuates cardiac fibrosis in the stroke-prone spontaneously hypertensive rat via the angiotensin type 2 receptor. Hypertension, 59 (2). pp. 300-307. ISSN 0194-911X (doi:10.1161/HYPERTENSIONAHA.111.177485)

Flores, M., Graham, D., Dominiczak, A. F., Milligan, G., Baker, A. H., and Nicklin, S. A. (2012) Abstract 231: angiotensin-(1-9) antagonises cardiac remodelling in a mouse model of Angiotensin Ii-induced hypertension. Hypertension, 60 . A231. ISSN 0194-911X

Hamilton, G., Evans, K.L., MacIntyre, D.J., Deary, I.J., Dominiczak, A.F., Smith, B.H., Morris, A.D., Porteous, D.J., and Thomson, P.A. (2012) Alzheimer's disease risk factor complement receptor 1 is associated with depression. Neuroscience Letters, 510 (1). pp. 6-9. ISSN 0304-3940 (doi:10.1016/j.neulet.2011.12.059)

Neisius, U. et al. (2012) Association of central and peripheral pulse pressure with intermediate cardiovascular phenoytpes. Journal of Hypertension, 30 (1). pp. 67-74. ISSN 0263-6352 (doi:10.1097/HJH.0b013e32834e12d8)

Padmanabhan, S., Newton-Cheh, C., and Dominiczak, A.F. (2012) Genetic basis of blood pressure and hypertension. Trends in Genetics, 28 (8). pp. 397-408. ISSN 0168-9525 (doi:10.1016/j.tig.2012.04.001)

Padmanabhan, S., and Dominiczak, A. F. (2012) Genetics and hypertension: which information for clinical practice. In: Berbari, A. E. and Mancia, G. (eds.) Special Issues in Hypertension. Springer Milan, Milan, pp. 439-452. ISBN 9788847026001

Salvi, E. et al. (2012) Genomewide Association study using a high-density single nucleotide polymorphism array and case-control design identifies a novel essential hypertension susceptibility locus in the promoter region of endothelial NO synthase. Hypertension, 59 (2). pp. 248-255. ISSN 0194-911X (doi:10.1161/HYPERTENSIONAHA.111.181990)

Xu, H. et al. (2012) Upregulation of junctional adhesion molecule-A is a putative prognostic marker of hypertension. Cardiovascular Research, 96 (3). pp. 552-560. ISSN 0008-6363 (doi:10.1093/cvr/cvs273)

2011

Johnson, T. et al. (2011) Blood pressure loci identified with a gene-centric array. American Journal of Human Genetics, 89 (6). pp. 688-700. ISSN 0002-9297 (doi:10.1016/j.ajhg.2011.10.013)

Ehret, G. B. et al. (2011) Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature, 478 (7367). pp. 103-109. ISSN 0028-0836 (doi:10.1038/nature10405)

Delles, C., Diez, J., and Dominiczak, A.F. (2011) Urinary proteomics in cardiovascular disease: achievements, limits and hopes. Proteomics Clinical Applications, 5 (5-6). pp. 222-232. ISSN 1862-8346 (doi:10.1002/prca.201000125)

Lanktree, M. B. et al. (2011) Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height. American Journal of Human Genetics, 88 (1). pp. 6-18. ISSN 0002-9297 (doi:10.1016/j.ajhg.2010.11.007 )

Bailey, E.L., Wardlaw, J.M., Graham, D., Dominiczak, A.F., Sudlow, C.L.M., and Smith, C. (2011) Cerebral small vessel endothelial structural changes predate hypertension in stroke-prone spontaneously hypertensive rats: a blinded, controlled immunohistochemical study of 5- to 21-week-old rats. Neuropathology and Applied Neurobiology, 37 (7). pp. 711-726. ISSN 0305-1846 (doi:10.1111/j.1365-2990.2011.01170.x)

Carty, D.M. et al. (2011) Urinary proteomics for prediction of preeclampsia. Hypertension, 57 (3). pp. 561-569. ISSN 0194-911X (doi:10.1161/HYPERTENSIONAHA.110.164285)

Denby, L. et al. (2011) miR-21 and miR-214 are consistently modulated during renal injury in rodent models. American Journal of Pathology, 179 (2). pp. 661-672. ISSN 0002-9440 (doi:10.1016/j.ajpath.2011.04.021)

Dominiczak, A.F. (2011) Replication of genome-wide association studies blood pressure hits in a large cohort. Journal of Hypertension, 29 (1). p. 32. ISSN 0263-6352 (doi:10.1097/HJH.0b013e328341c6c9)

Menni, C. et al. (2011) Evaluation of How Gene-Job Strain Interaction Affects Blood Pressure in the PAMELA Study. Psychosomatic Medicine, 73 (4). pp. 304-309. ISSN 0033-3174 (doi:10.1097/PSY.0b013e318212e0be)

Shah, S. et al. (2011) Four genetic loci influencing electrocardiographic indices of left ventricular hypertrophy. Circulation: Cardiovascular Genetics, 4 (6). pp. 626-635. ISSN 1942-325X (doi:10.1161/CIRCGENETICS.111.960203)

Soler Artigas, M. et al. (2011) Effect of five genetic variants associated with lung function on the risk of chronic obstructive lung disease, and their joint effects on lung function. American Journal of Respiratory and Critical Care Medicine, 184 (7). pp. 786-795. ISSN 1073-449X (doi:10.1164/rccm.201102-0192OC)

Yogi, A., Callera, G.E., Aranha, A.B., Antunes, T.T., Graham, D., McBride, M., Dominiczak, A., and Touyz, R.M. (2011) Sphingosine-1-Phosphate-Induced Inflammation Involves Receptor Tyrosine Kinase Transactivation in Vascular Cells: Upregulation in Hypertension. Hypertension, 57 (4). pp. 809-818. ISSN 0194-911X (doi:10.1161/HYPERTENSIONAHA.110.162719)

2010

Dominiczak, A.F., and Munroe, P.B. (2010) Genome-Wide association studies will unlock the genetic basis of hypertension: Pro side of the argument. Hypertension, 56 (6). pp. 1017-1020. ISSN 0194-911X (doi:10.1161/HYPERTENSIONAHA.110.156208)

Greig, J.A., Shirley, R., Graham, D., Denby, L., Dominiczak, A.F., Work, L.M., and Baker, A. (2010) Vascular-targeting anti-oxidant therapy in a model of hypertension and stroke. Journal of Cardiovascular Pharmacology, 56 (6). pp. 642-650. ISSN 0160-2446 (doi:10.1097/FJC.0b013e3181f8f19f)

Hopcroft, L. E.M., McBride, M. W., Harris, K. J., Sampson, A. K., McClure, J. D., Graham, D. , Young, G., Holyoake, T. L., Girolami, M. A., and Dominiczak, A. F. (2010) Predictive response-relevant clustering of expression data provides insights into disease processes. Nucleic Acids Research, 38 (20). pp. 6831-6840. ISSN 0305-1048 (doi:10.1093/nar/gkq550)

Good, D. M. et al. (2010) Naturally Occurring Human Urinary Peptides for Use in Diagnosis of Chronic Kidney Disease. Molecular and Cellular Proteomics, 9 (11). pp. 2424-2437. ISSN 1535-9476 (doi:10.1074/mcp.M110.001917)

Chambers, J. C. et al. (2010) Genetic loci influencing kidney function and chronic kidney disease. Nature Genetics, 42 (5). pp. 373-375. ISSN 1061-4036 (doi:10.1038/ng.566)

Craddock, N. et al. (2010) Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls. Nature, 464 (7289). 713-U86. ISSN 0028-0836 (doi:10.1038/nature08979)

Paul, L., Hastie, C. E., Li, W. S., Harrow, C., Muir, S., Connell, J. M.C., Dominiczak, A. F., McInnes, G. T., and Padmanabhan, S. (2010) Resting heart rate pattern during follow-up and mortality in hypertensive patients. Hypertension, 55 (2). pp. 567-574. ISSN 0194-911X (doi:10.1161/HYPERTENSIONAHA.109.144808)

Carty, D.A., Crichton, L., Alakandy, L., O'Dwyer, P., and Dominiczak, A. (2010) Hypertension in pregnancy:think laterally. European Journal of Obstetrics, Gynecology and Reproductive Biology, 150 (2). pp. 220-221. ISSN 0301-2115 (doi:10.1016/j.ejogrb.2010.03.005)

Carty, D.M., Delles, C., and Dominiczak, A.F. (2010) Preeclampsia and future maternal health. Journal of Hypertension, 28 (7). pp. 1349-1355. ISSN 0263-6352 (doi:10.1097/HJH.0b013e32833a39d0)

Delles, C., Dymott, J.A., Neisius, U., Rocchiccioli, J.P., Bryce, G.J., Moreno Zulategui, M.U., Carty, D.M., Berg, G.A., Hamilton, C.A., and Dominiczak, A.F. (2010) Reduced LDL-cholesterol levels in patients with coronary artery disease are paralelled by improved endothelial function: An observational study in patients from 2003 and 2007. Atherosclerosis, 211 (1). pp. 271-277. ISSN 0021-9150 (doi:10.1016/j.atherosclerosis.2010.01.014)

Delles, C., McBride, M.W., Graham, D., Padmanabhan, S., and Dominiczak, A.F. (2010) Genetics of hypertension: from experimental animals to humans. Biochimica et Biophysica Acta: Molecular Basis of Disease, 1802 (12). pp. 1299-1308. ISSN 0925-4439 (doi:10.1016/j.bbadis.2009.12.006)

Delles, C. et al. (2010) Urinary proteomic diagnosis of coronary artery disease: identification and clinical validation in 623 individuals. Journal of Hypertension, 28 (11). pp. 2316-2322. ISSN 0263-6352 (doi:10.1097/HJH.0b013e32833d81b7)

Dominiczak, A. F. et al. (2010) Systems biology to battle vascular disease. Nephrology, Dialysis, Transplantation, 25 (4). pp. 1019-1022. ISSN 0931-0509 (doi:10.1093/ndt/gfq025)

Fadini, G.P. et al. (2010) Urinary collagen fragments are significantly altered in diabetes: a link to pathophysiology. PLoS ONE, 5 (9). e13051. ISSN 1932-6203 (doi:10.1371/journal.pone.0013051)

Fairley, S., McClure, J., Hanlon, N., Irving, R., McBride, M., Dominiczak, A., and Hunt, E. (2010) Mapping affymetrix microarray probes to the rat genome via a persistent index. International Journal of Knowledge Discovery in Bioinformatics, 1 (1). pp. 48-65. ISSN 1947-9115 (doi:10.4018/jkdb.2010100204)

Graham, D., Koh-Tan, H. H. C., and Dominiczak, A. F. (2010) Reduced renal glutathione S-transferase mu type 1 expression in the stroke-prone spontaneously hypertensive rat. Journal of Hypertension, 28 (3). p. 634. ISSN 0263-6352 (doi:10.1097/HJH.0b013e328336902d)

Hastie, C. et al. (2010) Obesity paradox in a cohort of 4880 consecutive patients undergoing percutaneous coronary intervention. European Heart Journal, 31 (2). pp. 222-226. ISSN 0195-668X (doi:10.1093/eurheartj/ehp317)

Hastie, C. E., Padmanabhan, S., and Dominiczak, A. F. (2010) Genome-wide association studies of hypertension: light at the end of the tunnel. International Journal of Hypertension, 2010 (509581). ISSN 2090-0384 (doi:10.4061/2010/509581)

Lango Allen, H. et al. (2010) Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature, 467 (7317). pp. 832-838. ISSN 0028-0836 (doi:10.1038/nature09410)

Lindgren, C.M. et al. (2010) Genome-wide association scan meta-analysis identifies three loci influencing adiposity and fat distribution. PLoS Genetics, 6 (4). e1000508. ISSN 1553-7390 (doi:10.1371/journal.pgen.1000508)

Liu, J. Z. et al. (2010) Meta-analysis and imputation refines the association of 15q25 with smoking quantity. Nature Genetics, 42 (5). pp. 436-440. ISSN 1061-4036 (doi:10.1038/ng.572)

Luciano, M. et al. (2010) Shared genetic aetiology between cognitive ability and cardiovascular disease risk factors: Generation Scotland's Scottish family health study. Intelligence, 38 (3). pp. 304-313. ISSN 0160-2896 (doi:10.1016/j.intell.2010.03.002)

McCabe, C., Gallagher, L., Macrae, I.M., Gsell, W., Graham, D., and Dominiczak, A.F. (2010) Response to letter by Yao (Differences in the evolution of the ischemic penumbra in stroke-prone spontaneously hypertensive and Wistar-Kyoto rats). Stroke, 41 (4). E198-E199. ISSN 0039-2499 (doi:10.1161/STROKEAHA.109.575704)

Olsen, M.H. et al. (2010) Agreement within Europe about antihypertensive treatment and education – results from the European Society of Hypertension questionnaire. Journal of Hypertension, 28 (7). pp. 1593-1594. ISSN 0263-6352 (doi:10.1097/HJH.0b013e32833b7b08)

Padmanabhan, S., Hastie, C., Prabhakaran, D., and Dominiczak, A.F. (2010) Genomic approaches to coronary artery disease. Indian Journal of Medical Research, 132 (5). pp. 567-78. ISSN 0971-5916

Padmanabhan, S. et al. (2010) Genome-wide association study of blood pressure extremes identifies variant near UMOD associated with hypertension. PLoS Genetics, 6 (10). e1001177. ISSN 1553-7390 (doi:10.1371/journal.pgen.1001177)

Padmanabhan, S. et al. (2010) The effects of sex and method of blood pressure measurement on genetic associations with blood pressure in the PAMELA study. Journal of Hypertension, 28 (3). pp. 465-477. ISSN 0263-6352 (doi:10.1097/HJH.0b013e32833594d7)

Rocchiccioli, J.P., McMurray, J.J.V., and Dominiczak, A.F. (2010) Biomarkers in heart failure: a clinical review. Heart Failure Reviews, 15 (4). pp. 251-273. ISSN 1382-4147 (doi:10.1007/s10741-008-9123-9)

Sotoodehnia, N. et al. (2010) Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction. Nature Genetics, 42 (12). pp. 1068-1076. ISSN 1061-4036 (doi:10.1038/ng.716)

Taurino, C., Miller, W.H., McBride, M.W., McClure, J.D., Khanin, R., Moreno Zulategui, M.U., Dymott, J., Delles, C., and Dominiczak, A.F. (2010) Gene expression profiling in whole blood of patients with coronary artery disease. Clinical Science, 119 (8). pp. 335-343. ISSN 0143-5221 (doi:10.1042/CS20100043)

Teslovich, T.M. et al. (2010) Biological, clinical and population relevance of 95 loci for blood lipids. Nature, 466 (7307). pp. 707-713. ISSN 0028-0836 (doi:10.1038/nature09270)

2009

McCabe, C., Gallagher, L., Gsell, W., Graham, D., Dominiczak, A. F., and Macrae, I. M. (2009) Differences in the evolution of the ischemic penumbra in stroke-prone spontaneously hypertensive and Wistar-Kyoto rats. Stroke, 40 (12). pp. 3864-3868. ISSN 0039-2499 (doi:10.1161/STROKEAHA.109.559021)

Talmud, P. et al. (2009) Gene-centric association signals for lipids and apolipoproteins identified via the humanCVD BeadChip. American Journal of Human Genetics, 85 (5). pp. 628-642. ISSN 0002-9297 (doi:10.1016/j.ajhg.2009.10.014)

Nolte, I. M. et al. (2009) Common genetic variation near the phospholamban gene is associated with cardiac repolarisation: meta-analysis of three genome-wide association studies. PLoS ONE, 4 (7). e6138. ISSN 1932-6203 (doi:10.1371/journal.pone.0006138)

Sõber, S. et al. (2009) Targeting 160 candidate genes for blood pressure regulation with a genome-wide genotyping array. PLoS ONE, 4 (6). e6034. ISSN 1932-6203 (doi:10.1371/journal.pone.0006034)

Org, E. et al. (2009) Genome-wide scan identifies CDH13 as a novel susceptibility locus contributing to blood pressure determination in two European populations. Human Molecular Genetics, 18 (12). pp. 2288-2296. ISSN 0964-6906 (doi:10.1093/hmg/ddp135)

Newton-Cheh, C. et al. (2009) Genome-wide association study identifies eight loci associated with blood pressure. Nature Genetics, 41 (6). pp. 666-676. ISSN 1061-4036 (doi:10.1038/ng.361)

Newhouse, S. et al. (2009) Polymorphisms in the WNK1 gene are associated with blood pressure variation and urinary potassium excretion. PLoS ONE, 4 (4). e5003. ISSN 1932-6203 (doi:10.1371/journal.pone.0005003)

Padmanabhan, S., Hastie, C., Sainsbury, C., McBride, M. W., Connell, J. M., and Dominiczak, A. F. (2009) The cat, the fly and the beetle - why genetics needs a semantic education. International Journal of Semantic Computing, 3 (1). pp. 77-90. ISSN 1793-351X (doi:10.1142/S1793351X09000665)

Dominiczak, A. F., Delles, C., and Padmanabhan, S. (2009) Are isolated populations better for studying genes that predispose to hypertension? Journal of Hypertension, 27 (5). pp. 939-940.

Dominiczak, A., and Webb, R. (2009) David F. Bohr 1915-2008 In memoriam. Journal of Hypertension, 27 (3). pp. 660-661.

Graham, D., Huynh, N.N., Hamilton, C.A., Beattie, E.C., Smith, R.A.J., Cocheme, H.M., Murphy, M.P., and Dominiczak, A.F. (2009) Mitochondria-targeted antioxidant MitoQ(10) improves endothelial function and attenuates cardiac hypertrophy. Hypertension, 54 (2). 322-U233. ISSN 0194-911X (doi:10.1161/HYPERTENSIONAHA.109.130351)

Johannesson, M. et al. (2009) A resource for the simultaneous high-resolution mapping of multiple quantitative trait loci in rats: The NIH heterogeneous stock. Genome Research, 19 (1). pp. 150-158. ISSN 1088-9051 (doi:10.1101/gr.081497.108 )

Koh-Tan, H., Graham, D., Hamilton, C., Nicoll, G., Fields, L., McBride, M., Young, B., Young, B., and Dominiczak, A. (2009) Renal and vascular glutathione S-transferase mu is not affected by pharmacological intervention to reduce systolic blood pressure. Journal of Hypertension, 27 (8). pp. 1575-1584. ISSN 0263-6352 (doi:10.1097/HJH.0b013e32832cc5a1 )

Kolz, M. et al. (2009) Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations. PLoS Genetics, 5 (6). e1000504. ISSN 1553-7390 (doi:10.1371/journal.pgen.1000504)

Mancia, G. et al. (2009) Reappraisal of European guidelines on hypertension management: a European Society of Hypertension Task Force document. Blood Pressure, 18 (6). pp. 308-347. ISSN 0803-7051 (doi:10.3109/08037050903450468)

Mancia, G. et al. (2009) Reappraisal of European guidelines on hypertension management: a European Society of Hypertension Task Force document. Journal of Hypertension, 27 (11). pp. 2121-2158.

Masson, R. et al. (2009) Onset of experimental severe cardiac fibrosis is mediated by overexpression of angiotensin-converting enzyme 2. Hypertension, 53 (4). pp. 694-700. ISSN 0194-911X (doi:10.1161/HYPERTENSIONAHA.108.122333)

Mischak, H., Coon, J., Novak, J., Weissinger, E., Schanstra, J., and Dominiczak, A. (2009) Capillary Electrophoresis-Mass Spectrometry As A Powerful Tool in Biomarker Discovery and Clinical Diagnosis: An Update of Recent Developments. Mass Spectrometry Reviews, 28 (5). pp. 703-724. ISSN 0277-7037 (doi:10.1002/mas.20205 )

Padmanabhan, S., Menni, C., Prabhakaran, D., and Dominiczak, A. (2009) Discovering the genetic determinants of complex diseases. Current Science, 97 (3). pp. 385-391.

Work, L.M., Dominiczak, A.F., and McBride, M.W. (2009) The genetic basis of stroke: animal models. In: 3rd Report on Stroke: Genetic research in prevention and in cure. Il Pensiero Scientifico Editore, pp. 219-40.

zur Muhlen, C. et al. (2009) Evaluation of Urine Proteome Pattern Analysis for Its Potential To Reflect Coronary Artery Atherosclerosis in Symptomatic Patients. Journal of Proteome Research, 8 (1). pp. 335-345. ISSN 1535-3893 (doi:10.1021/pr800615t )

2008

Delles, C., McBride, M.W., Padmanabhan, S., and Dominiczak, A.F. (2008) The genetics of cardiovascular disease. Trends in Endocrinology and Metabolism, 19 (9). pp. 309-316. ISSN 1043-2760 (doi:10.1016/j.tem.2008.07.010 )

Caulfield, M. J. et al. (2008) SLC2A9 is a high-capacity urate transporter in humans. PLoS Medicine, 5 (10). e197. ISSN 1549-1277 (doi:10.1371/journal.pmed.0050197 )

Delles, C. et al. (2008) Glutathione S-transferase variants and hypertension. Journal of Hypertension, 26 (7). pp. 1343-1352. ISSN 0263-6352 (doi:10.1097/HJH.0b013e3282fe1d67)

Padmanabhan, S., Melander, O., Hastie, C., Menni, C., Delles, C., Connell, J. M., and Dominiczak, A. F. (2008) Hypertension and genome-wide association studies: combining high fidelity phenotyping and hypercontrols. Journal of Hypertension, 26 (7). pp. 1275-1281. ISSN 0263-6352 (doi:10.1097/HJH.0b013e3282ff634f)

Berry, C., Zimmerli, L.U., Steedman, T., Foster, J.E., Dargie, H.J., Berg, H.A., Dominiczak, A.F., and Delles, C. (2008) Cardiac magnetic resonance findings predict increased resource utilization in elective coronary artery bypass grafting. Clinical Science, 114 (6). pp. 423-430. ISSN 0140-8736 (doi:10.1042/CS20070337)

Wallace, C. et al. (2008) Genome-wide association study identifies genes for biomarkers of cardiovascular disease: Serum urate and dyslipiclemia. American Journal of Human Genetics, 82 (1). pp. 139-149. ISSN 0002-9297 (doi:10.1016/j.ajhg.2007.11.001)

Carty, D., Delles, C., and Dominiczak, A. (2008) Novel Biomarkers for Predicting Preeclampsia. Trends in Cardiovascular Medicine, 18 (5). pp. 186-194. ISSN 1050-1738 (doi:10.1016/j.tcm.2008.07.002)

Coon, J.J. et al. (2008) CE-MS analysis of the human urinary proteome for biomarker discovery and disease diagnostics. Proteomics Clinical Applications, 2 (7-8). pp. 964-973. ISSN 1862-8346 (doi:10.1002/prca.200800024)

Delles, C., Miller, W. H., and Dominiczak, A. F. (2008) Targeting reactive oxygen species in hypertension. Antioxidants and Redox Signaling, 10 (6). pp. 1061-1077. ISSN 1523-0864 (doi:10.1089/ars.2007.2008 )

Delles, C., Neisius, U., Dymott, J., Carty, D., Rocchiccioli, J., Bryce, G., Berg, G., Hamilton, C., and Dominiczak, A. (2008) Strategies to target cholesterol levels lead to improved endothelial function in patients with coronary artery disease (CAD). Journal of Hypertension, 26 . S325-S325. ISSN 0263-6352

Dymott, J.A., Chow, C., Rocchiccioli, J.P., Berg, G.A., Cherry, A.K.L., Delles, C., Hamilton, C.A., and Dominiczak, A.F. (2008) Endothelial function in patients undergoing coronary artery by-pass grafting is improved in patients in 2006 compared to 2003. Scottish Medical Journal, 53 (1). p. 57. ISSN 0036-9330

Hastie, C., Padmanabhan, S., Slack, R., Dominiczak, A., and Pell, J. (2008) Factors that predict survival following Percutaneous coronary intervention in patients with and without hypertension. Journal of Hypertension, 26 . S113-S113. ISSN 0263-6352

Miller, W., Graham, D., Douglas, K., MacKenzie, R., and Dominiczak, A. (2008) Metabolic phenotypes in SHRSP and chromosome 2 congenic strains. Journal of Human Hypertension, 22 (10). pp. 736-737. ISSN 0950-9240

Miller, W., Graham, D., Douglas, K., Mackenzie, R., Huynh, N., and Dominiczak, A. (2008) Characterisation of metabolic phenotypes in the SHRSP using chromosome 2 congenic strains. Journal of Hypertension, 26 (Suppl.). S340-S341. ISSN 0263-6352

Moreno, M., Dymott, J., Taurino, C., Berg, G., Carty, D., Mc Culloch, J., Delles, C., and Dominiczak, A. (2008) Whole blood and mononuclear cell superoxide generation are increased in patients with coronary artery disease. Journal of Hypertension, 26 . S308-S308.

Moreno, M., Dymott, J., Taurino, C., Carty, D., Mc Culloch, J., Delles, C., and Dominiczak, A. (2008) Exercise attenuates superoxide release in whole blood and mononuclear cells in patients with coronary artery disease. Journal of Hypertension, 26 . S320-S320.

Padmanabhan, S., Menni, C., Lee, W., Brambilla, P., Laing, S., Sega, R., Cesana, G., Mancia, G., and Dominiczak, A. (2008) Cardiovascular gene centric association study of metabolic syndrome and ambulatory blood pressure in the PAMELA study. Journal of Hypertension, 26 . S18-S18.

Tian, T., McBride, M.W., Graham, D., Touyz, R., and Dominiczak, A.F. (2008) A systems biology approach for the sphingosine-1-phosphate signal transduction in vascular smooth muscle cell. Journal of Hypertension, 26 (Suppl.). S148-S148. ISSN 0263-6352

Tonyz, R., Aranha, A., Yogi, A., Graham, D., McBride, M., Callera, G., Montezano, A., Coimbra, T., and Dominiczak, A. (2008) Increased vascular sphingosine-1-phosphate signaling in SHRSP is due to post-receptor mechanisms. Journal of Hypertension, 26 (Suppl.). S329-S329. ISSN 0263-6352

Weedon, M. et al. (2008) Genome-wide association analysis identifies 20 loci that influence adult height. Nature Genetics, 40 (5). pp. 575-583.

Zimmerli, L.U. et al. (2008) Urinary proteomic biomarkers on coronary artery disease. Molecular and Cellular Proteomics, 7 (2). pp. 290-298. ISSN 1535-9476 (doi:10.1074/mcp.M700394-MCP200)

Zulategui, M., Dymott, J., Taurino, C., Berg, G., Rocchiccioli, J., Delles, C., and Dominiczak, A. (2008) Superoxide release by whole blood and mononuclear cells as markers of oxidative stress in patients with coronary artery disease. Journal of Human Hypertension, 22 (10). p. 733.

de Ujue, M., Zulategui, M., Dymott, J., Taurino, C., Berg, G., Rocchiccioli, P., Delles, C., and Dominiczak, A. (2008) Relationship between whole blood and mononuclear cell superoxide levels in patients with coronary artery disease. Hypertension, 52 (4). E55-E56. ISSN 0194-911X

2007

Freel, E.M. et al. (2007) Phenotypic consequences of variation across the aldosterone synthase and 11-beta hydroxylase locus in a hypertensive cohort: data from the MRC BRIGHT Study. Clinical Endocrinology, 67 (6). pp. 832-838. ISSN 0300-0664 (doi:10.1111/j.1365-2265.2007.02971.x)

Bailey, S. et al. (2007) Mutations in the gene encoding the 3 '-5 ' DNA exonuclease TREX1 are associated with systemic lupus erythematosus. Nature Genetics, 39 . pp. 1065-1067. (doi:10.1038/ng2091)

Barr, M. et al. (2007) Polymorphic variation in the 11 beta-hydroxylase gene associates with reduced 11-hydroxylase efficiency. Hypertension, 49 . pp. 113-119. (doi:10.1161/01.HYP.0000249904.93940.7a)

Burton, P.R. et al. (2007) Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature, 447 (7145). pp. 661-678. ISSN 0028-0836 (doi:10.1038/nature05911)

Burton, P. R. et al. (2007) Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants. Nature Genetics, 39 (11). pp. 1329-1337. ISSN 1061-4036 (doi:10.1038/ng.2007.17)

Chow, C., Pell, A., Walker, A., O'Dowd, C., Dominiczak, A., and Pell, J. (2007) Families of patients with premature coronary heart disease: an obvious but neglected target for primary prevention. British Medical Journal, 335 . pp. 481-485. ISSN 0959-535X

Good, D., Thongboonkerd, V., Novak, J., Bascands, J., Schanstra, J., Coon, J., Dominiczak, A., and Mischak, H. (2007) Body fluid proteomics for biomarker discovery: lessons from the past hold the key to success in the future. Journal of Proteome Research, 6 (12). pp. 4549-4555. ISSN 1535-3893

Graham, D. et al. (2007) Candidate genes that determine response to salt in the stroke-prone spontaneously hypertensive rat - Congenic analysis. Hypertension, 50 . pp. 1134-1141. (doi:10.1161/HYPERTENSIONAHA.107.095349)

Jakubowska, J., Hunt, E., Chalmers, M., McBride, M., and Dominiczak, A. F. (2007) VisGenome: visualization of single and comparative genome representations. Bioinformatics, 23 (19). pp. 2641-2642. ISSN 1367-4803 (doi:10.1093/bioinformatics/btm394)

Lee-Kirsch, M. et al. (2007) Mutations in the gene encoding the 3'-5' DNA exonuclease TREX1 are associated with systemic lupus erythematosus. Nature Genetics, 39 (9). pp. 1065-1067. ISSN 1061-4036 (doi:10.1038/ng2091 )

Mancia, G. et al. (2007) [ESH/ESC 2007 Guidelines for the management of arterial hypertension]. Rev Esp Cardiol, 60 (9). pp. 968-994.

Mancia, G. et al. (2007) 2007 Guidelines for the management of arterial hypertension - The task force for the management of arterial hypertension of the European society of hypertension (ESH) and of the European society of cardiology (ESC). European Heart Journal, 28 . pp. 1462-1536. (doi:10.1093/eurheartj/ehm236)

Mancia, G. et al. (2007) 2007 ESH-ESC practice guidelines for the management of arterial hypertension - ESH-ESC task force on the management of arterial hypertension. Journal of Hypertension, 25 . pp. 1751-1762.

Mancia, G. et al. (2007) [Practice guidelines 2007 for the treatment of arterial hypertension]. Giornale Italiano di Cardiologia, 8 (7). pp. 389-479.

Mansia, G. et al. (2007) 2007 ESH-ESC Guidelines for the management of arterial hypertension: the task force for the management of arterial hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). Blood Press, 16 (3). pp. 135-232.

Marcano, A. C. B. et al. (2007) Genetic association analysis of inositol polyphosphate phosphatase-like 1 (INPPL1, SHIP2) variants with essential hypertension. Journal of Medical Genetics, 44 . (doi:10.1136/jmg.2007.049718)

Nawrot, T., Staessen, J., Roels, H., Den Hond, E., Thijs, L., Fagard, R., Dominiczak, A., and Struijker-Boudier, H. (2007) Blood pressure and blood selenium: a cross-sectional and longitudinal population study. European Heart Journal, 28 . pp. 628-633. (doi:10.1093/eurheartj/ehl479)

Newhouse, S. et al. (2007) Association of the WNK1 gene with essential hypertension, blood pressure variability and serum and urine electrolytes. Journal of Human Hypertension, 21 (10). p. 831.

Newhouse, S. et al. (2007) Novel associations of the Wnk1 gene with risk for essential hypertension and electrolyte homeostasis. Circulation Research, 101 (11). p. 1208.

Padmanabhan, S. et al. (2007) Association of the CYP11B1 and CYP11B2 gene polymorphisms with hypertension in the British Genetics of Hypertension case-control study. Journal of Human Hypertension, 21 (10). p. 837.

Padmanabhan, S. et al. (2007) Urinary albumin excretion in hypertensive siblings in the British Genetics of Hypertension study. Journal of Human Hypertension, 21 (10). p. 843.

Shankar, R., Charchar, F., Eckert, G., Saha, C., Tu, W., Dominiczak, A., and Pratt, J. (2007) Studies of an association in boys of blood pressure and the Y chromosome. American Journal of Hypertension, 20 . pp. 27-31. (doi:10.1016/j.amjhyper.2006.06.013)

Tomaszewski, M., Charchar, F., Lynch, M., Padmanabhan, S., Wang, W., Miller, W., Grzeszczak, W., Maric, C., Zukowska-Szczechowska, E., and Dominiczak, A. (2007) Fibroblast growth factor 1 gene and hypertension: from the quantitative trait locus to positional analysis. Circulation, 116 (17). pp. 1915-1924.

Tomaszewski, M., Charchar, F., Lynch, M., Padmanabhan, S., Wang, W., Miller, W., Grzeszczak, W., Maric, C., Zukowska-Szczechowska, E., and Dominiczak, A. (2007) Fibroblast growth factor 1 gene and hypertension - From the quantitative trait locus to positional analysis. Circulation, 116 . pp. 1915-1924. (doi:10.1161/CIRCULATIONAHA.107.710293)

Tomaszewski, M., Charchar, F., Maric, C., McClure, J., Crawford, L., Grzeszczak, W., Sattar, N., Zukowska-Szczechowska, E., and Dominiczak, A. (2007) Glomerular hyperfiltration: A new marker of metabolic risk. Kidney International, 71 . pp. 816-821. ISSN 0085-2538 (doi:10.1038/sj.ki.5002160)

Wallace, C. et al. (2007) Discovery of novel genes for serum urate and low-density lipoprotein cholesterol - Two biomarkers of cardiovascular disease. Circulation Research, 101 (11). p. 1208.

Zimmerli, L., Mark, P., Steedman, T., Foster, J., Berg, G., Dargie, H., Jardine, A., Delles, C., and Dominiczak, A. (2007) Vascular function in patients with end-stage renal disease and/or coronary artery disease: A cardiac magnetic resonance imaging study. Kidney International, 71 . pp. 68-73. ISSN 0085-2538 (doi:10.1038/sj.ki.5002024)

2006

Al Benna, S., Hamilton, C.A., McClure, J.D., Rogers, P.N., Berg, G.A., Ford, I., Delles, C., and Dominiczak, A.F. (2006) Low-density lipoprotein cholesterol determines oxidative stress and endothelial dysfunction in saphenous veins from patients with coronary artery disease. Arteriosclerosis, Thrombosis and Vascular Biology, 26 . pp. 218-223. ISSN 1079-5642 (doi:10.1161/01.ATV.0000193626.22269.45)

Bell, J. et al. (2006) Two-dimensional genome-scan identifies novel epistatic loci for essential hypertension. Human Molecular Genetics, 15 . pp. 1365-1374. (doi:10.1093/hmg/ddl058)

Delles, C. et al. (2006) Association between variants of the human GSTM gene family and hypertension. Hypertension, 48 (4). E27-E27. ISSN 0194-911X

Delles, C., and Dominiczak, A. (2006) Vascular failure or sick vessel syndrome: The cardiovascular continuum is a useful concept for clinical research. Journal of Hypertension, 24 (11). pp. 2147-2148. ISSN 0263-6352

Delles, C. et al. (2006) Variants of the human mu type glutathione-s-transferase (GSTM) gene family are associated with hypertension. Journal of Hypertension, 24 . S13-S13.

Hamilton, C., Groves, S., Carswell, H., Brosnan, M., Graham, D., and Dominiczak, A. (2006) Estrogen treatment enhances nitric oxide bioavailability in normotensive but not hypertensive rats. American Journal of Hypertension, 19 . pp. 859-866. (doi:10.1016/j.amjhyper.2006.01.008)

Ibrahim, J., McGee, A., Graham, D., McGrath, J.C., and Dominiczak, A.F. (2006) Sex-specific differences in cerebral arterial myogenic tone in hypertensive and normotensive rats. American Journal of Physiology: Heart and Circulatory Physiology, 290 . H1081-H1089. ISSN 0363-6135 (doi:10.1152/ajpheart.00752.2005)

McBride, M., Graham, D., Delles, C., and Dominiczak, A. (2006) Functional genomics in hypertension. Current Opinion in Nephrology and Hypertension, 15 . pp. 145-151.

Munroe, P. et al. (2006) Increased support for linkage of a novel locus on chromosome 5q13 for essential hypertension in the British genetics of hypertension study. Hypertension, 48 . pp. 105-111. (doi:10.1161/01.HYP.0000228324.74255.f1)

Padmanabhan, S. et al. (2006) Genomewide linkage analysis for loci affecting electrocardiographic LV mass. Journal of Hypertension, 24 . S330-S330.

Padmanabhan, S. et al. (2006) Chromosome 2p shows significant linkage to antihypertensive response in the British genetics of hypertension study. Hypertension, 47 . pp. 603-608. (doi:10.1161/01.HYP.0000197947.62601.9d)

Smith, B.H. et al. (2006) Generation Scotland: the Scottish family health study; a new resource for researching genes and heritability. BMC Medical Genetics, 7 . p. 74. ISSN 1471-2350 (doi:10.1186/1471-2350-7-74 )

Tomaszewski, M., Moreno, M., Charchar, F., Zukowska-Szczechowska, E., and Dominiczak, A. (2006) Functional significance of single nucleotide polymorphisms within the 5'-flanking region of beta2-adrenergic receptor gene. Journal of Hypertension, 24 (12). pp. 2473-2474. ISSN 0263-6352

Tomaszewski, M., Zimmerli, L., Charchar, F., and Dominiczak, A. (2006) Genetic information in the diagnosis and treatment of hypertension. Current Hypertension Reports, 8 . pp. 309-316.

Wallace, C. et al. (2006) Linkage analysis using co-phenotypes in the BRIGHT study reveals novel potential susceptibility loci for hypertension. American Journal of Human Genetics, 79 . pp. 323-331.

2005

Tomaszewski, M., Charchar, F.J., Zukowska-Szczechowska, E., Grzeszczak, W., and Dominiczak, A.F. (2005) Letter re: Inflammation and lipoprotein changes with protracted exercise. Journal of Clinical Endocrinology and Metabolism, 90 (8). p. 4981. ISSN 0021-972X

Brain, N.J.R., and Dominiczak, A.F. (2005) Pharmacogenomics in hypertension: present practicalities and future potential. Journal of Hypertension, 23 (7). pp. 1327-1329. ISSN 0263-6352

Carswell, H., Dominiczak, A., Garcia-Segura, L., Harada, N., Hutchison, J., and Macrae, I. (2005) Brain aromatase expression after experimental stroke: Topography and time course. Journal of Steroid Biochemistry and Molecular Biology, 96 . pp. 89-91. (doi:10.1016/j.jsbmb.2005.02.016)

Carswell, H., McBride, M., Graham, D., Dominiczak, A., and Macrae, I. (2005) Mutant animal models of stroke and gene expression: the stroke-prone spontaneously hypertensive rat. Methods in Molecular Medicine, 104 . pp. 49-74.

Collison, M., James, D., Graham, D., Holman, G., Connell, J., Dominiczak, A.F., Gould, G., and Salt, I. (2005) Reduced insulin-stimulated GLUT4 bioavailability in stroke-prone spontaneously hypertensive rats. Diabetologia, 48 (3). pp. 539-546. ISSN 0012-186X (doi:10.1007/s00125-005-1674-x)

Dominiczak, A. (2005) Disentangling fetal and maternal susceptibility for pre-eclampsia: a British multicenter candidate-gene study. American Journal of Human Genetics, 77 (1). pp. 127-131. ISSN 0002-9297 (doi:10.1086/431245)

Dominiczak, A. F., Graham, D., McBride, M. W., Brain, N. J.R., Lee, W. K., Charchar, F. J., Tomaszewski, M., Delles, C., and Hamilton, C. A. (2005) Corcoran Lecture. Cardiovascular genomics and oxidative stress. Hypertension, 45 (4). pp. 636-642. ISSN 0194-911X (doi:10.1161/01.HYP.0000154253.53134.09)

Graham, D., McBride, M., Brain, N., and Dominiczak, A. (2005) Congenic/consomic models of hypertension. Methods in Molecular Medicine, 108 . pp. 3-15.

McBride, M. et al. (2005) Reduction of Gstm1 expression in the stroke-prone spontaneously hypertension rat contributes to increased oxidative stress. Hypertension, 45 . pp. 786-792. (doi:10.1161/01.HYP.0000154879.49245.39)

McCallum, R., Hamilton, C., Graham, D., Jardine, E., Connell, J., and Dominiczak, A. (2005) Vascular responses to IGF-I and insulin are impaired in aortae of hypertensive rats. Journal of Hypertension, 23 . pp. 351-358.

McCallum, R., Sainsbury, C., Spiers, A., Dominiczak, A., Petrie, J., Sattar, N., and Connell, J. (2005) Growth hormone replacement reduces C-reactive protein and large-artery stiffness but does not alter endothelial function in patients with adult growth hormone deficiency. Clinical Endocrinology, 62 (4). pp. 473-479. ISSN 0300-0664 (doi:10.1111/j.1365-2265.2005.02245.x)

McGill, J.K., Gallagher, L., Carswell, H.V.O., Irving, E.A., Dominiczak, A.F., and Macrae, I.M. (2005) Impaired functional recovery after stroke in the stroke-prone spontaneously hypertensive rat. Stroke, 36 (1). pp. 135-141. ISSN 0039-2499 (doi:10.1161/01.STR.0000149629.32525.b7)

Miller, W.H., Nicklin, S.A., Baker, A.H., and Dominiczak, A. (2005) Gene transfer and the cardiovascular system. In: Raizada, M.K., Paton, J.F.R., Kasparov, S. and Katovich, M.J. (eds.) Cardiovascular Genomics. Series: Contemporary cardiology . Humana Press, Totowa, NJ, USA, pp. 175-196. ISBN 9781588294005

Miller, W., Brosnan, M., Graham, D., Nicol, C., Morecroft, I., Channon, K., Danilov, S., Reynolds, P., Baker, A., and Dominiczak, A. (2005) Targeting endothelial cells with adenovirus expressing nitric oxide synthase prevents elevation of blood pressure in stroke-prone spontaneously hypertensive rats. Molecular Therapy, 12 . pp. 321-327. (doi:10.1016/j.ymthe.2005.02.025)

Nemoto, K. et al. (2005) No involvement of the nerve growth factor gene locus in hypertension in spontaneously hypertensive rats. Hypertension Research, 28 (2). pp. 155-163. ISSN 0916-9636

Newhouse, S. et al. (2005) Haplotypes of the WNK1 gene associate with blood pressure variation in a severely hypertensive population from the British Genetics of Hypertension study. Human Molecular Genetics, 14 . pp. 1805-1814. (doi:10.1093/hmg/ddi187)

Padmanabhan, S., Munroe, P.B., Brown, M., Clayton, D., Farrall, M., Webster, J., Lathrop, M., Caulfield, M., Dominiczak, A.F., and Connell, J. (2005) Chromosome 2p shows genome wide significant linkage to anti-hypertensive medication response in the British genetics hypertension (BRIGHT) study. Hypertension, 46 (4). p. 886. ISSN 0194-911X

Strahorn, P., Graham, D., Charchar, F., Sattar, N., McBride, M., and Dominiczak, A. (2005) Genetic determinants of metabolic syndrome components in the stroke-prone spontaneously hypertensive rat. Journal of Hypertension, 23 . pp. 2179-2186.

Wallace, C. et al. (2005) Loci on chromosomes 5p and 20q are linked to multiple hypertension phenotypes in the BRItish Genetics of HyperTension (BRIGHT) study. p. 877.

2004

McBride, M.W., Charchar, F.J., Graham, D., Miller, W.H., Strahorn, P., Carr, F.J., and Dominiczak, A.F. (2004) Functional genomics in rodent models of hypertension. Journal of Physiology, 554 . pp. 56-63. ISSN 0022-3751 (doi:10.1113/jphysiol.2003.049361)

Antier, D., Carswell, H., Brosnan, M., Hamilton, C., Macrae, I., Groves, S., Jardine, E., Reid, J., and Dominiczak, A. (2004) Increased levels of superoxide in brains from old female rats. Free Radical Research, 38 . pp. 177-183. (doi:10.1080/10715760310001643294)

Carswell, H.V., Bingham, D., Wallace, K., Nilsen, M., Graham, D.I., Dominiczak, A.F., and Macrae, I.M. (2004) Differential effects of 17beta-estradiol upon stroke damage in stroke prone and normotensive rats. Journal of Cerebral Blood Flow and Metabolism, 24 (3). pp. 298-304. ISSN 0271-678X

Carswell, H., Bingham, D., Wallace, K., Nilsen, M., Graham, D., Dominiczak, A., and Macrae, I. (2004) Differential effects of 17 beta-estradiol upon stroke damage in stroke prone and normotensive rats. Journal of Cerebral Blood Flow and Metabolism, 24 . pp. 298-304. (doi:10.1097/01.WCB.0000112322.75217.FD)

Charchar, F., Padmanabhan, S., Anderson, N.H., Tomaszewski, M., Upton, M.N., McConnachie, A., Connell, J.M., Watt, G.C.M., Dominiczak, A.F., and Charchar, F.J. (2004) Y chromsome variant is a predictor of cardiovascular mortality. Journal of Hypertension: Supplement, 22 (S1). S58-S59. ISSN 0952-1178

Charchar, F.J., Tomaszewski, M., Lacka, B., Zakrzewski, J., Zukowska-Szczechowska, E., Grzeszczak, W., and Dominiczak, A.F. (2004) Association of the human Y chromosome with cholesterol levels in the general population. Arteriosclerosis, Thrombosis and Vascular Biology, 24 . pp. 308-312. ISSN 1079-5642 (doi:10.1161/01.ATV.0000113291.39267.0a)

Dominiczak, A., Brain, N., Charchar, F., McBride, M., Hanlon, N., and Lee, W. (2004) Genetics of hypertension: Lessons learnt from Mendelian and polygenic syndromes. Clinical and Experimental Hypertension, 26 . pp. 611-620. (doi:10.1081/CEH-200031939)

Graham, D., Hamilton, C., Beattie, E., Spiers, A., and Dominiczak, A. (2004) Comparison of the effects of omapatrilat and irbesartan hydrochlorothiazide on endothelial function and cardiac hypertrophy in the stroke-prone spontaneously hypertensive rat: sex differences. Journal of Hypertension, 22 (2). pp. 329-337. ISSN 0263-6352 (doi:10.1097/01.hjh.0000098240.58662.93)

Graham, D., Hamilton, C., Beattie, E., Spiers, A., and Dominiczak, A.F. (2004) Comparison of the effects of omapatrilat and irbesartan/hydrochlorothiazide on endothelial function and cardiac hypertrophy in the stroke-prone spontaneously hypertensive rat: sex differences. Journal of Hypertension, 22 (2). pp. 329-337. ISSN 0263-6352

Hamilton, C., Miller, W., Al Benna, S., Brosnan, M., Drummond, R., McBride, M., and Dominiczak, A. (2004) Strategies to reduce oxidative stress in cardiovascular disease. Clinical Science, 106 . pp. 219-234. (doi:10.1042/CS20030379)

Hunt, E., Hanlon, N., Leader, D.P., Bryce, H., and Dominiczak, A.F. (2004) The visual language of synteny. OMICS: A Journal of Integrative Biology, 8 . pp. 289-305.

Kuznetsova, T. et al. (2004) Relationship between left ventricular mass and the ACE D/I polymorphism varies according to sodium intake. Journal of Hypertension, 22 (2). pp. 287-295. ISSN 0263-6352

Newhouse, S. et al. (2004) No association of the WNK1 gene with essential hypertension in the MRC BRIGHT study. Journal of Hypertension, 22 . S212-S212.

Padmanabhan, S., Connell, J.M.C., Dominiczak, A.F., Inglis, G., Macfarlane, P.W., and Watt, G. (2004) Heritability and genetic determinants of electrocardiographic measures of left ventricular mass - a two generation family study. Journal of Hypertension: Supplement, 22 (S1). S180-S181. ISSN 0952-1178

Sinnott, R.O. et al. (2004) Grid services supporting the usage of secure federated, distributed biomedical data. In: Proceedings of UK e-Science All Hands Meeting, 31 Aug - 3 Sept 2004, Nottingham, UK.

Tomaszewski, M., Charchar, F., Crawford, L., Zukowska-Sczechowska, E., Grzeszczak, W., Sattar, N., and Dominiczak, A. (2004) Serum C-reactive protein and lipids in ultra-marathon runners. American Journal of Cardiology, 94 . pp. 125-126. (doi:10.1016/j.amjcard.2004.03.043)

Tomaszewski, M., Charchar, F., Lacka, B., Pesonen, U., Wang, W., Zukowska-Szczechowska, E., Grzeszczak, W., and Dominiczak, A. (2004) Epistatic interaction between beta2-adrenergic receptor and neuropeptide Y genes influences LDL-cholesterol in hypertension. pp. 689-694.

Tomaszewski, M., Charchar, F., Lacka, B., Pesonen, U., Wang, W., Zukowska-Szczechowska, E., Grzeszczak, W., and Dominiczak, A. (2004) Epistatic interaction between beta(2)-adrenergic receptor and neuropeptide Y genes influences LDL-cholesterol in hypertension. Hypertension, 44 . pp. 689-694. (doi:10.1161/01.HYP.0000143844.81979.61)

2003

Stanton, T., Payne, J.R., Montgomery, H.E., Watt, G., Dominiczak, A.F., Jardine, A.G., and Connell, J.M. (2003) Genetic determinants of left ventricular mass: the role of beta-1 adrenoceptor variation in normal, athletic, and disease populations. Journal of the American College of Cardiology, 41 (6 (S1)). p. 273. ISSN 0735-1097 (doi:10.1016/S0735-1097(03)82282-9)

Brown, M., Cruickshank, J., Dominiczak, A., MacGregor, G., Poulter, N., Russell, G., Thom, S., and Williams, B. (2003) Better blood pressure control: how to combine drugs. Journal of Human Hypertension, 17 . pp. 81-86. (doi:10.1038/sj.jhh.1001511)

Caulfield, M. et al. (2003) Genome-wide mapping of human loci for essential hypertension. Lancet, 361 (9375). pp. 2118-2123. ISSN 0140-6736 (doi:10.1016/S0140-6736(03)13722-1)

Charchar, F., Tomaszewski, M., Strahorn, P., Champagne, B., and Dominiczak, A. (2003) Y is there a risk to being male? Trends in Endocrinology and Metabolism, 14 . pp. 163-168. ISSN 1043-2760 (doi:10.1016/S1043-2760(02)00032-8)

Dominiczak, A.F., and McBride, M.W. (2003) Genetics of common polygenic stroke. Nature Genetics, 35 (2). pp. 116-117.

Izzard, A.S., Graham, D., Burnham, M.P., Heerkens, E.H., Dominiczak, A.F., and Heagerty, A.M. (2003) Myogenic and structural properties of cerebral arteries from the stroke-prone spontaneously hypertensive rat. American Journal of Physiology: Heart and Circulatory Physiology, 285 . H1489-H1494. ISSN 0363-6135 (doi:10.1152/ajpheart.00352.2003)

Khan, I.Y., Taylor, P.D., Dekou, V., Seed, P.T., Lakasing, L., Graham, D., Dominiczak, A.F., Hanson, M.A., and Poston, L. (2003) Gender-linked hypertension in offspring of lard-fed pregnant rats. Hypertension, 41 (1). pp. 168-175. ISSN 0194-911X

Khan, L., Taylor, P., Dekou, V., Seed, P., Lakasing, L., Graham, D., Dominiczak, A., Hanson, M., and Poston, L. (2003) Gender-linked hypertension in offspring of lard-fed pregnant rat. Hypertension, 41 . pp. 168-175. (doi:10.1161/01.HYP.0000047511.97879.FC)

McBride, M., Carr, F., Graham, D., Anderson, N., Clark, J., Lee, W., Charchar, F., Brosnan, M., and Dominiczak, A. (2003) Microarray analysis of rat chromosome 2 congenic strains. Hypertension, 41 . pp. 847-853. (doi:10.1161/01.HYP.0000047103.07205.03)

Pell, J., Smith, G., Dominiczak, A., Cobbe, S., Dobbie, R., McMahon, A., and Ford, I. (2003) Family history of premature death from ischaemic heart disease is associated with an increased risk of delivering a low birth weight baby. Heart, 89 (10). pp. 1249-1250. (doi:10.1136/heart.89.10.1249 )

Stanton, T., Robb, S., Payne, J., Montgomery, H., Watt, G., McDonagh, T., Dominiczak, A., Connell, J., and Dargie, H. (2003) The effect of beta-1 adrenoceptor genetic variation on left ventricular mass. Circulation, 108 (17). p. 180.

Tomaszewski, M., Charchar, F.J., Padmanabhan, S., Zukowska-Szczechowska, E., Grzeszczak, W., and Dominiczak, A.F. (2003) Cardiovascular diseases and G-protein beta 3 subunit gene (GNB3) in the era of genomewide scans. Journal of Human Hypertension, 17 (6). pp. 379-380. ISSN 0950-9240 (doi:10.1038/sj.jhh.1001559)

Tomaszewski, M. et al. (2003) Strikingly low circulating CRP concentrations in ultramarathon runners independent of markers of adiposity - How low can you go? Arteriosclerosis, Thrombosis and Vascular Biology, 23 (9). pp. 1640-1644. ISSN 1079-5642 (doi:10.1161/01.ATV.0000087036.75849.0B)

Ye, P. et al. (2003) Cardiac aldosterone synthase (CYP11B2) gene expression is not increased in the fibrotic heart. p. 635.

2002

Tomaszewski, M. et al. (2002) Essential hypertension and beta(2)-adrenergic receptor gene linkage and association analysis. Hypertension, 40 (3). pp. 286-291. ISSN 0194-911X

Brosnan, M., Hamilton, C., Graham, D., Lygate, C., Jardine, E., and Dominiczak, A. (2002) Irbesartan lowers superoxide levels and increases nitric oxide bioavailability in blood vessels from spontaneously hypertensive stroke-prone rats. Journal of Hypertension, 20 . pp. 281-286.

Carr, F.J., Negrin, C.D., Clark, J.S., Graham, D., McBride, M.W., Anderson, N.W., and Dominiczak, A.F. (2002) Chromosome 2 reciprocal congenic strains to evaluate the effect of the genetic background on blood pressure. Scottish Medical Journal, 47 (1). pp. 7-9. ISSN 0036-9330

Carr, F., McBride, M., Carswell, H., Graham, D., Strahorn, P., Clark, J., Charchar, F., and Dominiczak, A. (2002) Genetic aspects of stroke: Human and experimental studies. Journal of Cerebral Blood Flow and Metabolism, 22 . pp. 767-773.

Caulfield, M. et al. (2002) The MRC British Genetics of Hypertension Study - Genome-wide screen results. Journal of Hypertension, 20 . S7-S7.

Charchar, F.J. et al. (2002) The Y chromosome effect on blood pressure in two European populations. Hypertension, 39 . pp. 353-356. ISSN 0194-911X

Duncan, A., Petrie, J., Brosnan, M., Devlin, A., Bass, R., Charnock-Jones, D., Connell, J., Dominiczak, A., and Lumsden, M. (2002) Is estradiol cardioprotection a nitric oxide-mediated effect? Human Reproduction, 17 (7). pp. 1918-1923. ISSN 0268-1161 (doi:10.1093/humrep/17.7.1918)

Fennell, J., Brosnan, M., Frater, A., Hamilton, C., Alexander, M., Nicklin, S., Heistad, D., Baker, A., and Dominiczak, A. (2002) Adenovirus-mediated overexpression of extracellular superoxide dismutase improves endothelial dysfunction in a rat model of hypertension. Gene Therapy, 9 . pp. 110-117. (doi:10.1038/sj/gt/3301633)

Hamilton, C., Brosnan, M., Al Benna, S., Berg, G., and Dominiczak, A. (2002) NAD(P)H oxidase inhibition improves endothelial function in rat and human blood vessels. Hypertension, 40 (5). pp. 755-762.

Hamilton, C., O'Dowd, G., McIntosh, L., Berg, G., Butler, J., Pathi, V., Williams, R., Reid, J., and Dominiczak, A. (2002) Vasorelaxant properties of isolated human radial arteries: comparison with internal mammary arteries. Atherosclerosis, 160 . pp. 345-353. ISSN 0021-9150

McBride, M., Carswell, H., Graham, D., Carr, F., Charchar, F., Macrae, I., and Dominiczak, A. (2002) Genetic and gender determinants of cerebrovascular disease. Seminars in Nephrology, 22 . pp. 127-134. (doi:10.1053/snep.2002.30213)

McCallum, R.W., Hamilton, C., Graham, D., Jardine, E., Dominiczak, A.F., and Connell, J. (2002) Hypertensive but not normotensive rat arteries display impaired nitric oxide-dependant vasodilatation to insulin-like growth factor and insulin. Journal of Hypertension, 20 . S284-S284.

McCallum, R., Petrie, J., Dominiczak, A., and Connell, J. (2002) Growth hormone deficiency and vascular risk. Clinical Endocrinology, 57 (1). pp. 11-24. ISSN 0300-0664 (doi:10.1046/j.1365-2265.2002.01559.x)

Padmanabhan, S., Padmanabhan, A., Dominiczak, A.F., and Connell, J. (2002) A web-based hypertension genetics resource. Journal of Hypertension, 20 . S24-S24.

Stanton, T., Inglis, G.C., Padmanabhan, S., Dominiczak, A.F., Jardine, A.G., and Connell, J.M. (2002) Variation at the beta-1 adrenoceptor gene locus affects left ventricular mass in renal failure. Journal of Nephrology, 15 (5). pp. 512-518.

Stanton, T., Padmanabhan, S., Payne, J.R., Watt, G., Montgomery, H.E., Jardine, A.G., Dominiczak, A.F., and Connell, J. (2002) The role of beta-1 adrenoceptor variation in determining LV mass in normal, athletic and disease populations. Hypertension, 40 (4). p. 576. ISSN 0194-911X

2001

Berry, C., Anderson, N., Kirk, A., Dominiczak, A., and McMurray, J. (2001) Renin angiotensin system inhibition is associated with reduced free radical concentrations in arteries of patients with coronary heart disease. Heart, 86 (2). pp. 217-220.

Berry, C., Brosnan, M., Alexander, M., Hamilton, C., McMurray, J., and Dominiczak, A.F. (2001) Mechanisms of oxidative free radical generation in human arteries. Clinical Science , 101 (2). 7P.

Berry, C., Brosnan, M., Fennell, J., Hamilton, C., and Dominiczak, A. (2001) Oxidative stress and vascular damage in hypertension. Current Opinion in Nephrology and Hypertension, 10 . pp. 247-255.

Berry, C., Touyz, R., Dominiczak, A.F., Webb, R.C., and Johns, D.G. (2001) Angiotensin receptors: signaling, vascular pathophysiology, and interactions with ceramide. American Journal of Physiology: Heart and Circulatory Physiology, 281 . H2337-H2365. ISSN 0363-6135

Cohuet, G., Challande, P., Osborne-Pellegrin, M., Arribas, S., Dominiczak, A., Louis, H., Laurent, S., and Lacolley, P. (2001) Mechanical strength of the isolated carotid artery in SHR. Hypertension, 38 . pp. 1167-1171.

De Lange, R.P., Burr, K., Clark, J.S., Negrin, C.D., Brosnan, M.J., St Clair, D.M., Dominiczak, A.F., and Shaw, D.J. (2001) Mapping and sequencing rat dishevelled-1: a candidate gene for cerebral ischaemic insult in a rat model of stroke. Neurogenetics, 3 (2). pp. 99-106.

Dorrance, A., Graham, D., Webb, R., Fraser, R., and Dominiczak, A. (2001) Increased membrane sphingomyelin and arachidonic acid in stroke-prone spontaneously hypertensive rats. American Journal of Hypertension, 14 . pp. 1149-1153.

Hamilton, C.A., McPhaden, A.R., Berg, G., Pathi, V., and Dominiczak, A.F. (2001) Is hydrogen peroxide an EDHF in human radial arteries? American Journal of Physiology: Heart and Circulatory Physiology, 280 . H2451-H2455. ISSN 0363-6135

Hamilton, C., Brosnan, M., McIntyre, M., Graham, D., and Dominiczak, A. (2001) Superoxide excess in hypertension and aging - A common cause of endothelial dysfunction. Hypertension, 37 . pp. 529-534.

James, D.J., Cairns, F., Salt, I.P., Murphy, G.J., Dominiczak, A.F., Connell, J.M.C., and Gould, G.W. (2001) Skeletal muscle of stroke-prone spontaneously hypertensive rats exhibits reduced insulin-stimulated glucose transport and elevated levels of caveolin and flotillin. Diabetes, 50 (9). pp. 2148-2156. ISSN 0012-1797 (doi:10.2337/diabetes.50.9.2148 )

Jamieson, A., Ingham, D.G., Dominiczak, A.F., and Connell, J.M. (2001) Not the usual cause of superior vena cava obstruction. Scottish Medical Journal, 46 (2). pp. 51-52. ISSN 0036-9330

Knight, J. et al. (2001) No support for linkage of chromosome 17(q21-24) to Essential Hypertension in the MRC British Genetics of Hypertension (MRC BRIGHT) Study. American Journal of Human Genetics, 69 (4). p. 559.

MacKay, A., Hamilton, C., McArthur, K., Berg, G., Tropeano, A., Boutouyrie, P., Reid, J., and Dominiczak, A. (2001) Radial artery hypertrophy occurs in coronary atherosclerosis and is independent of blood pressure. Clinical Science, 100 . pp. 509-516.

MacKenzie, C.J., Wakefield, J.M., Cairns, F., Dominiczak, A.F., and Gould, G.W. (2001) Regulation of glucose transport in aortic smooth muscle cells by cAMP and cGMP. Biochemical Journal, 353 . pp. 513-519. ISSN 0264-6021

Marks, L., Carswell, H., Peters, E., Graham, D., Patterson, J., Dominiczak, A., and Macrae, I. (2001) Characterization of the microglial response to cerebral ischemia in the stroke-prone spontaneously hypertensive rat. Hypertension, 38 . pp. 116-122.

McCallum, R., Hamilton, C., Graham, D., Jardine, E., Connell, J., and Dominiczak, A. F. (2001) Insulin-like growth factor acts as a NO-dependant vasodilator in normotensive but not hypertensive rat arteries. p. 968.

Negrin, C., McBride, M., Carswell, H., Graham, D., Carr, F., Clark, J., Jeffs, B., Anderson, N., Macrae, I., and Dominiczak, A. (2001) Reciprocal consomic strains to evaluate Y chromosome effects. Hypertension, 37 . pp. 391-397.

Nicklin, S., Reynolds, P., Brosnan, M., White, S., Curiel, D., Dominiczak, A., and Baker, A. (2001) Analysis of cell-specific promoters for viral gene therapy targeted at the vascular endothelium. Hypertension, 38 . pp. 65-70.

Nicklin, S., Von Seggern, D., Work, L., Pek, D., Dominiczak, A., Nemerow, G., and Baker, A. (2001) Ablating adenovirus type 5 fiber-CAR binding and HI loop insertion of the SIGYPLP peptide generate an endothelial cell-selective adenovirus. Molecular Therapy, 4 (6). pp. 534-542. ISSN 1525-0016 (doi:10.1006/mthe.2001.0489)

Petrie, J., Collison, M., Connell, J., Gould, G., and Dominiczak, A. (2001) CD36 deficiency and insulin resistance. Lancet, 358 (9277). pp. 242-243. ISSN 0140-6736 (doi:10.1016/S0140-6736(01)05428-9)

Stanton, T., Jardine, A. G., Dominiczak, A. F., and Connell, J. (2001) Genetic determinants of left ventricular mass: The role of beta-1 adrenoceptor variation. Circulation, 104 (17). p. 197. ISSN 0009-7322

Zicha, J., Negrin, C., Dobesova, Z., Carr, F., Vokurkova, M., McBride, M., Kunes, J., and Dominiczak, A. (2001) Altered Na+-K+ pump activity and plasma lipids in salt-hypertensive Dahl rats: relationship to Atp1a1 gene. Physiol Genomics, 6 (2). pp. 99-104.

2000

Caulfield, M. et al. (2000) A new tool for checks of data precision within the MRC British genetics of hypertension study. Journal of Hypertension, 18 . S180-S180.

Collison, M., Campbell, I., Salt, I., Dominiczak, A., Connell, J., Lyall, H., and Gould, G. (2000) Sex hormones induce insulin resistance in 3T3-L1 adipocytes by reducing cellular content of IRS proteins. Diabetologia, 43 (11). pp. 1374-1380. ISSN 0012-186X (doi:10.1007/s001250051541)

Collison, M., Glazier, A., Graham, D., Morton, J., Dominiczak, M., Aitman, T., Connell, J., Gould, G., and Dominiczak, A. F. (2000) Cd36 and molecular mechanisms of insulin resistance in the stroke-prone spontaneously hypertensive rat. Diabetes, 49 (12). pp. 2222-2226.

Graham, D., Collison, M., Glazier, A., Morton, J., Aitman, T., Connell, J., Gouid, G., and Dominiczak, A. F. (2000) Cd36 gene and molecular mechanisms in insulin resistance in the SHRSP. Journal of Hypertension, 18 . S173-S173.

Munroe, P. et al. (2000) Analysis of the angiotensinogen gene in the MRC British genetics of Hypertension study. American Journal of Human Genetics, 67 (4). p. 304.

1998

Dominiczak, A., Jeffs, B., and Connell, J. (1998) New genetic concepts in hypertensive cardiovascular disease. Current Opinion in Cardiology, 13 (5). pp. 304-311.

1997

Jeffs, B., Clark, J.S., Anderson, N.H., Gratton, J., Brosnan, M.J., Gauguier, D., Reid, J.L., Macrae, I.M., and Dominiczak, A.F. (1997) Sensitivity to cerebral ischaemic insult in a rat model of stroke is determined by a single genetic locus. Nature Genetics, 16 (4). pp. 364-367. ISSN 1061-4036 (doi:10.1038/ng0897-364)

Harden, P., MacLeod, M., Rodger, R., Baxter, G., Connell, J., Dominiczak, A., Junor, B., Briggs, J., and Moss, J. (1997) Effect of renal-artery stenting on progression of renovascular renal failure. Lancet, 349 (9059). pp. 1133-1136.

1995

MacLeod, M., Taylor, A., Baxter, G., Harden, P., Briggs, D., Moss, J., Semple, P., Connell, J., and Dominiczak, A. (1995) Renal artery stenosis managed by Palmaz stent insertion: Technical and clinical outcome. Journal of Hypertension, 13 (12). pp. 1791-1795.

MacLeod, M., Connell, J., Harden, P., Briggs, J., Moss, J., and Dominiczak, A. (1995) Transluminal Vascular Stents for Ostial Atherosclerotic Renal-Artery Stenosis. Lancet, 346 (8982). pp. 1109-1110.

1990

O'Connell, J., Dominiczak, A., Isles, C., McLellan, A., Davidson, G., Gray, C., and Connell, J. (1990) A Comparison of Calcium Pentagastrin and Trh Tests in Screening for Medullary Carcinoma of the Thyroid in Men-Iia. Clinical Endocrinology, 32 (4). pp. 417-423. ISSN 0300-0664 (doi:10.1111/j.1365-2265.1990.tb00881.x)

This list was generated on Mon Sep 15 14:59:36 2014 BST.
Number of items: 288.

Article

Arking, D. E. et al. (2014) Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization. Nature Genetics, 46 (8). pp. 826-836. ISSN 1061-4036 (doi:10.1038/ng.3014)

Tragante, V. et al. (2014) Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple blood-pressure-related loci. American Journal of Human Genetics, 94 (3). pp. 349-360. ISSN 0002-9297 (doi:10.1016/j.ajhg.2013.12.016)

Graham, L. A. et al. (2014) Validation of uromodulin as a candidate gene for human essential hypertension. Hypertension, 63 (3). pp. 551-558. ISSN 0194-911X (doi:10.1161/HYPERTENSIONAHA.113.01423)

McLachlan, J., Beattie, E., Murphy, M. P., Koh-Tan, C. H.H., Olson, E., Beattie, W., Dominiczak, A. F., Nicklin, S. A., and Graham, D. (2014) Combined therapeutic benefit of mitochondria-targeted antioxidant, MitoQ10, and angiotensin receptor blocker, losartan, on cardiovascular function. Journal of Hypertension, 32 (3). pp. 555-564. ISSN 0263-6352 (doi:10.1097/HJH.0000000000000054)

Carty, D.M., Neisius, U., Rooney, L., Dominiczak, A., and Delles, C. (2014) Pulse wave analysis for prediction of preeclampsia. Journal of Human Hypertension, 28 (2). pp. 98-104. ISSN 0950-9240 (doi:10.1038/jhh.2013.64)

Carty, D.M., Neisius, U., Rooney, L.K., Dominiczak, A.F., and Delles, C. (2014) Pulse wave analysis for the prediction of preeclampsia. Journal of Human Hypertension, 28 (2). pp. 98-104. ISSN 0950-9240 (doi:10.1038/jhh.2013.64)

Mancia, G. et al. (2014) 2013 ESH/ESC practice guidelines for the management of arterial hypertension. Blood Pressure, 23 (1). pp. 3-16. ISSN 0803-7051 (doi:10.3109/08037051.2014.868629)

Bailey, E. L., McBride, M. W., Crawford, W., McClure, J. D., Graham, D., Dominiczak, A. F., Sudlow, C. L.M., Smith, C., and Wardlaw, J. M. (2014) Differential gene expression in multiple neurological, inflammatory and connective tissue pathways in a spontaneous model of human small vessel stroke. Neuropathology and Applied Neurobiology . ISSN 0305-1846 (doi:10.1111/nan.12116) (Early Online Publication)

Beattie, C. J., Fulton, R. L., Higgins, P., Padmanabhan, S., McCallum, L., Walters, M. R., Dominiczak, A. F., Touyz, R. M., and Dawson, J. (2014) Allopurinol initiation and change in blood pressure in older adults with hypertension. Hypertension . ISSN 0194-911X (doi:10.1161/HYPERTENSIONAHA.114.03953) (Early Online Publication)

Dominiczak, A.F., and Fink, G.D. (2014) Celebrating 35 years of success. Hypertension, 63 (1). pp. 2-3. ISSN 0194-911X (doi:10.1161/HYPERTENSIONAHA.113.02762)

Holmes, M. V. et al. (2014) Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data. BMJ, 349 . g4164. ISSN 1756-1833 (doi:10.1136/bmj.g4164)

Holmes, M. V. et al. (2014) Mendelian randomization of blood lipids for coronary heart disease. European Heart Journal . ISSN 0195-668X (doi:10.1093/eurheartj/eht571)

McCallum, L. et al. (2014) Response to effect of serum chloride on mortality in hypertensive patients. Hypertension, 63 (3). e15-e15. ISSN 0194-911X (doi:10.1161/HYPERTENSIONAHA.113.02926)

Norsworthy, P. J. et al. (2014) Targeted genetic testing for familial hypercholesterolaemia using next generation sequencing: a population-based study. BMC Medical Genetics, 15 (1). p. 70. ISSN 1471-2350 (doi:10.1186/1471-2350-15-70)

Williamson, C. et al. (2014) Family history of premature cardiovascular disease: blood pressure control and long-term mortality outcomes in hypertensive patients. European Heart Journal, 35 (9). pp. 563-570. ISSN 0195-668X (doi:10.1093/eurheartj/eht539)

Yoneyama, S. et al. (2014) Gene-centric meta-analyses for central adiposity traits in up to 57 412 individuals of European descent confirm known loci and reveal several novel associations. Human Molecular Genetics, 23 (9). pp. 2498-2510. ISSN 0964-6906 (doi:10.1093/hmg/ddt626)

McCallum, L. et al. (2013) Serum chloride is an independent predictor of mortality in hypertensive patients. Hypertension, 62 (5). pp. 836-843. ISSN 0194-911X (doi:10.1161/HYPERTENSIONAHA.113.01793)

Hastie, C., Sloan, W., Dominiczak, A., Morrison, D., and Padmanabhan, S. (2013) Long-term and ultra long-term blood pressure variability during follow-up and mortality in 14 522 patients with hypertension. Hypertension, 62 (4). pp. 698-705. ISSN 0194-911X (doi:10.1161/HYPERTENSIONAHA.113.01343)

Mancia, G. et al. (2013) 2013 practice guidelines for the management of arterial hypertension of the European Society of Hypertension (ESH) and the European Society of Cardiology (ESC). Journal of Hypertension, 31 (10). pp. 1925-1938. ISSN 0263-6352 (doi:10.1097/HJH.0b013e328364ca4c)

Goodson, N.J., Smith, B.H., Hocking, L.J., McGilchrist, M.M., Dominiczak, A.F., Morris, A., Porteous, D.J., and Goebel, A. (2013) Cardiovascular risk factors associated with the metabolic syndrome are more prevalent in people reporting chronic pain: Results from a cross-sectional general population study. Pain, 154 (9). pp. 1595-1602. ISSN 0304-3959 (doi:10.1016/j.pain.2013.04.043)

Rossi, S. H. et al. (2013) Impaired renal function impacts negatively on vascular stiffness in patients with coronary artery disease. BMC Nephrology, 14 (173). ISSN 1471-2369 (doi:10.1186/1471-2369-14-173)

Atanur, S.S. et al. (2013) Genome sequencing reveals loci under artificial selection that underlie disease phenotypes in the laboratory rat. Cell, 154 (3). pp. 691-703. ISSN 0092-8674 (doi:10.1016/j.cell.2013.06.040)

Aubini è re-Robb, L. et al. (2013) Blood pressure response to patterns of weather fluctuations and effect on mortality. Hypertension, 62 (1). pp. 190-196. ISSN 0194-911X (doi:10.1161/HYPERTENSIONAHA.111.00686)

Smith, B. H. et al. (2013) Generation Scotland: Scottish family health study. A profile of the study, its participants, and their potential for genetic research on health and illness. International Journal of Epidemiology, 42 (3). pp. 689-700. ISSN 0300-5771 (doi:10.1093/ije/dys084)

Carty, D.M., Dominiczak, A., and Delles, C. (2013) Pulse wave analysis for prediction of preeclampsia. Endocrine Reviews, 34 (3). SAT-520. ISSN 0163-769X

MacKenzie, R.M. et al. (2013) Mitochondrial reactive oxygen species enhance AMP-activated protein kinase activation in the endothelium of patients with coronary artery disease and diabetes. Clinical Science, 124 (6). pp. 403-411. ISSN 0143-5221 (doi:10.1042/CS20120239)

Alvarez-Madrazo, S. et al. (2013) Common polymorphisms in the CYP11B1 and CYP11B2 genes: evidence for a digenic influence on hypertension. Hypertension, 61 (1). pp. 232-239. ISSN 0194-911X (doi:10.1161/HYPERTENSIONAHA.112.200741)

Baud, A. et al. (2013) Combined sequence-based and genetic mapping analysis of complex traits in outbred rats. Nature Genetics, 45 (7). pp. 767-775. ISSN 1061-4036 (doi:10.1038/ng.2644)

Brittain, J.F. et al. (2013) An MRI-histological study of white matter in stroke-free SHRSP. Journal of Cerebral Blood Flow and Metabolism, 33 (5). pp. 760-763. ISSN 0271-678X (doi:10.1038/jcbfm.2013.14)

Dawson, J. et al. (2013) Acetaminophen use and change in blood pressure in a hypertensive population. Journal of Hypertension, 31 (7). pp. 1485-1490. ISSN 0263-6352 (doi:10.1097/HJH.0b013e328360f6f8)

Dawson, J. et al. (2013) Serum uric acid level, longitudinal blood pressure, renal function, and long-term mortality in treated hypertensive patients. Hypertension, 62 (1). pp. 105-111. ISSN 0194-911X (doi:10.1161/HYPERTENSIONAHA.113.00859)

Dominiczak, A. (2013) Hypertension: update 2013. Hypertension, 61 (1). p. 2. ISSN 0194-911X (doi:10.1161/HYPERTENSIONAHA.111.00667)

Hastie, C. et al. (2013) Long-term and ultra-long term blood pressure variability during follow–up and mortality in 14522 patients with hypertension. Hypertension, 62 (4). pp. 698-705. ISSN 0194-911X (doi:10.1161/HYPERTENSIONAHA.113.01343)

Koh-Tan, H.H. C., McBride, M. W., McClure, J. D., Beattie, E., Young, B., Dominiczak, A. F., and Graham, D. (2013) Interaction between chromosome 2 and 3 regulates pulse pressure in the stroke-prone spontaneously hypertensive rat. Hypertension, 62 (1). pp. 33-40. ISSN 0194-911X (doi:10.1161/HYPERTENSIONAHA.111.00814)

Mancia, G. et al. (2013) 2013 ESH/ESC guidelines for the management of arterial hypertension: the task force for the management of arterial hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). European Heart Journal, 34 (28). pp. 2159-2219. ISSN 0195-668X (doi:10.1093/eurheartj/eht151)

McDonough, C.W., Gong, Y., Padmanabhan, S., Burkley, B., Langaee, T.Y., Melander, O., Pepine, C.J., Dominiczak, A.F., Cooper-DeHoff, R.M., and Johnson, J.A. (2013) Pharmacogenomic association of nonsynonymous SNPs in SIGLEC12, A1BG, and the selectin region and cardiovascular outcomes. Hypertension, 62 (1). pp. 48-54. ISSN 0194-911X (doi:10.1161/HYPERTENSIONAHA.111.00823)

Smith, B.H. et al. (2013) Cohort profile: Generation Scotland: Scottish Family Health Study (GS:SFHS). The study, its participants and their potential for genetic research on health and illness. International Journal of Epidemiology, 42 (3). pp. 689-700. ISSN 0300-5771 (doi:10.1093/ije/dys084)

Turner, S.T. et al. (2013) Genomic association analysis of common variants influencing antihypertensive response to hydrochlorothiazide. Hypertension, 62 . pp. 391-397. ISSN 0194-911X (doi:10.1161/HYPERTENSIONAHA.111.00436)

Sanna-Cherchi, S. et al. (2012) Copy-number disorders are a common cause of congenital kidney malformations. American Journal of Human Genetics, 91 (6). pp. 987-997. ISSN 0002-9297 (doi:10.1016/j.ajhg.2012.10.007)

Mackenzie, R.M., Sandrim, V.C., Carty, D.M., McClure, J.D., Freeman, D.J., Dominiczak, A.F., McBride, M.W., and Delles, C. (2012) Endothelial FOS expression and pre-eclampsia. BJOG: An International Journal of Obstetrics and Gynaecology, 119 (13). pp. 1564-1571. ISSN 1470-0328 (doi:10.1111/1471-0528.12016)

Asselbergs, F.W. et al. (2012) Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. American Journal of Human Genetics, 91 (5). pp. 823-838. ISSN 0002-9297 (doi:10.1016/j.ajhg.2012.08.032)

Paul, L. et al. (2012) Hematocrit predicts long-term mortality in a nonlinear and sex-specific manner in hypertensive adults. Hypertension, 60 (3). pp. 631-638. ISSN 0194-911X (doi:10.1161/HYPERTENSIONAHA.112.191510)

Hocking, L.J. et al. (2012) Heritability of chronic pain in 2195 extended families. European Journal of Pain, 16 (7). pp. 1053-1063. ISSN 1090-3801 (doi:10.1002/j.1532-2149.2011.00095.x)

Carty, D.M., Anderson, L.A., Freeman, D.J., Welsh, P.I., Brennand, J.E., Dominiczak, A.F., and Delles, C. (2012) Early pregnancy soluble E-selectin concentrations and risk of preeclampsia. Journal of Hypertension, 30 (5). pp. 954-959. ISSN 0263-6352 (doi:10.1097/HJH.0b013e328352573b)

Saxena, R. et al. (2012) Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci. American Journal of Human Genetics, 90 (3). pp. 410-425. ISSN 0002-9297 (doi:10.1016/j.ajhg.2011.12.022)

Currie, G., Freel, E. M., Perry, C. G., and Dominiczak, A. F. (2012) Disorders of blood pressure regulation — role of catecholamine biosynthesis, release, and metabolism. Current Hypertension Reports, 14 (1). pp. 38-45. ISSN 1522-6417 (doi:10.1007/s11906-011-0239-2)

Carty, D.M., Anderson, L.A., Duncan, C.N., Baird, D., Rooney, L.K., Dominiczak, A.F., and Delles, C. (2012) Peripheral arterial tone: assessment of microcirculatory function in pregnancy. Journal of Hypertension, 30 (1). pp. 117-123. ISSN 0263-6352 (doi:10.1097/HJH.0b013e32834d76fb)

Charchar, F.J. et al. (2012) Inheritance of coronary artery disease in men: an analysis of the role of the Y chromosome. Lancet, 379 (9819). pp. 915-922. ISSN 0140-6736 (doi:10.1016/S0140-6736(11)61453-0)

Dominiczak, A.F. (2012) Hypertension: update 2012. Hypertension, 59 (4). pp. 753-754. ISSN 0194-911X (doi:10.1161/HYP.0b013e31824f9ffe)

Flores, M., Graham, D., Dominiczak, A.F., Milligan, G., Baker, A.H., and Nicklin, S.A. (2012) Angiotensin-(1-9) antagonises Angiotensin II-induced cardiac remodeling via the angiotensin type 2 receptor. Proceedings of the Physiological Society, 27 . C1. ISSN 1749-6187

Flores, M., Work, L.M., Douglas, K., Denby, L., Dominiczak, A.F., Graham, D., and Nicklin, S.A. (2012) Angiotensin-(1-9) attenuates cardiac fibrosis in the stroke-prone spontaneously hypertensive rat via the angiotensin type 2 receptor. Hypertension, 59 (2). pp. 300-307. ISSN 0194-911X (doi:10.1161/HYPERTENSIONAHA.111.177485)

Flores, M., Graham, D., Dominiczak, A. F., Milligan, G., Baker, A. H., and Nicklin, S. A. (2012) Abstract 231: angiotensin-(1-9) antagonises cardiac remodelling in a mouse model of Angiotensin Ii-induced hypertension. Hypertension, 60 . A231. ISSN 0194-911X

Hamilton, G., Evans, K.L., MacIntyre, D.J., Deary, I.J., Dominiczak, A.F., Smith, B.H., Morris, A.D., Porteous, D.J., and Thomson, P.A. (2012) Alzheimer's disease risk factor complement receptor 1 is associated with depression. Neuroscience Letters, 510 (1). pp. 6-9. ISSN 0304-3940 (doi:10.1016/j.neulet.2011.12.059)

Neisius, U. et al. (2012) Association of central and peripheral pulse pressure with intermediate cardiovascular phenoytpes. Journal of Hypertension, 30 (1). pp. 67-74. ISSN 0263-6352 (doi:10.1097/HJH.0b013e32834e12d8)

Padmanabhan, S., Newton-Cheh, C., and Dominiczak, A.F. (2012) Genetic basis of blood pressure and hypertension. Trends in Genetics, 28 (8). pp. 397-408. ISSN 0168-9525 (doi:10.1016/j.tig.2012.04.001)

Salvi, E. et al. (2012) Genomewide Association study using a high-density single nucleotide polymorphism array and case-control design identifies a novel essential hypertension susceptibility locus in the promoter region of endothelial NO synthase. Hypertension, 59 (2). pp. 248-255. ISSN 0194-911X (doi:10.1161/HYPERTENSIONAHA.111.181990)

Xu, H. et al. (2012) Upregulation of junctional adhesion molecule-A is a putative prognostic marker of hypertension. Cardiovascular Research, 96 (3). pp. 552-560. ISSN 0008-6363 (doi:10.1093/cvr/cvs273)

Johnson, T. et al. (2011) Blood pressure loci identified with a gene-centric array. American Journal of Human Genetics, 89 (6). pp. 688-700. ISSN 0002-9297 (doi:10.1016/j.ajhg.2011.10.013)

Ehret, G. B. et al. (2011) Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature, 478 (7367). pp. 103-109. ISSN 0028-0836 (doi:10.1038/nature10405)

Delles, C., Diez, J., and Dominiczak, A.F. (2011) Urinary proteomics in cardiovascular disease: achievements, limits and hopes. Proteomics Clinical Applications, 5 (5-6). pp. 222-232. ISSN 1862-8346 (doi:10.1002/prca.201000125)

Lanktree, M. B. et al. (2011) Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height. American Journal of Human Genetics, 88 (1). pp. 6-18. ISSN 0002-9297 (doi:10.1016/j.ajhg.2010.11.007 )

Bailey, E.L., Wardlaw, J.M., Graham, D., Dominiczak, A.F., Sudlow, C.L.M., and Smith, C. (2011) Cerebral small vessel endothelial structural changes predate hypertension in stroke-prone spontaneously hypertensive rats: a blinded, controlled immunohistochemical study of 5- to 21-week-old rats. Neuropathology and Applied Neurobiology, 37 (7). pp. 711-726. ISSN 0305-1846 (doi:10.1111/j.1365-2990.2011.01170.x)

Carty, D.M. et al. (2011) Urinary proteomics for prediction of preeclampsia. Hypertension, 57 (3). pp. 561-569. ISSN 0194-911X (doi:10.1161/HYPERTENSIONAHA.110.164285)

Denby, L. et al. (2011) miR-21 and miR-214 are consistently modulated during renal injury in rodent models. American Journal of Pathology, 179 (2). pp. 661-672. ISSN 0002-9440 (doi:10.1016/j.ajpath.2011.04.021)

Dominiczak, A.F. (2011) Replication of genome-wide association studies blood pressure hits in a large cohort. Journal of Hypertension, 29 (1). p. 32. ISSN 0263-6352 (doi:10.1097/HJH.0b013e328341c6c9)

Menni, C. et al. (2011) Evaluation of How Gene-Job Strain Interaction Affects Blood Pressure in the PAMELA Study. Psychosomatic Medicine, 73 (4). pp. 304-309. ISSN 0033-3174 (doi:10.1097/PSY.0b013e318212e0be)

Shah, S. et al. (2011) Four genetic loci influencing electrocardiographic indices of left ventricular hypertrophy. Circulation: Cardiovascular Genetics, 4 (6). pp. 626-635. ISSN 1942-325X (doi:10.1161/CIRCGENETICS.111.960203)

Soler Artigas, M. et al. (2011) Effect of five genetic variants associated with lung function on the risk of chronic obstructive lung disease, and their joint effects on lung function. American Journal of Respiratory and Critical Care Medicine, 184 (7). pp. 786-795. ISSN 1073-449X (doi:10.1164/rccm.201102-0192OC)

Yogi, A., Callera, G.E., Aranha, A.B., Antunes, T.T., Graham, D., McBride, M., Dominiczak, A., and Touyz, R.M. (2011) Sphingosine-1-Phosphate-Induced Inflammation Involves Receptor Tyrosine Kinase Transactivation in Vascular Cells: Upregulation in Hypertension. Hypertension, 57 (4). pp. 809-818. ISSN 0194-911X (doi:10.1161/HYPERTENSIONAHA.110.162719)

Dominiczak, A.F., and Munroe, P.B. (2010) Genome-Wide association studies will unlock the genetic basis of hypertension: Pro side of the argument. Hypertension, 56 (6). pp. 1017-1020. ISSN 0194-911X (doi:10.1161/HYPERTENSIONAHA.110.156208)

Greig, J.A., Shirley, R., Graham, D., Denby, L., Dominiczak, A.F., Work, L.M., and Baker, A. (2010) Vascular-targeting anti-oxidant therapy in a model of hypertension and stroke. Journal of Cardiovascular Pharmacology, 56 (6). pp. 642-650. ISSN 0160-2446 (doi:10.1097/FJC.0b013e3181f8f19f)

Hopcroft, L. E.M., McBride, M. W., Harris, K. J., Sampson, A. K., McClure, J. D., Graham, D. , Young, G., Holyoake, T. L., Girolami, M. A., and Dominiczak, A. F. (2010) Predictive response-relevant clustering of expression data provides insights into disease processes. Nucleic Acids Research, 38 (20). pp. 6831-6840. ISSN 0305-1048 (doi:10.1093/nar/gkq550)

Good, D. M. et al. (2010) Naturally Occurring Human Urinary Peptides for Use in Diagnosis of Chronic Kidney Disease. Molecular and Cellular Proteomics, 9 (11). pp. 2424-2437. ISSN 1535-9476 (doi:10.1074/mcp.M110.001917)

Chambers, J. C. et al. (2010) Genetic loci influencing kidney function and chronic kidney disease. Nature Genetics, 42 (5). pp. 373-375. ISSN 1061-4036 (doi:10.1038/ng.566)

Craddock, N. et al. (2010) Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls. Nature, 464 (7289). 713-U86. ISSN 0028-0836 (doi:10.1038/nature08979)

Paul, L., Hastie, C. E., Li, W. S., Harrow, C., Muir, S., Connell, J. M.C., Dominiczak, A. F., McInnes, G. T., and Padmanabhan, S. (2010) Resting heart rate pattern during follow-up and mortality in hypertensive patients. Hypertension, 55 (2). pp. 567-574. ISSN 0194-911X (doi:10.1161/HYPERTENSIONAHA.109.144808)

Carty, D.A., Crichton, L., Alakandy, L., O'Dwyer, P., and Dominiczak, A. (2010) Hypertension in pregnancy:think laterally. European Journal of Obstetrics, Gynecology and Reproductive Biology, 150 (2). pp. 220-221. ISSN 0301-2115 (doi:10.1016/j.ejogrb.2010.03.005)

Carty, D.M., Delles, C., and Dominiczak, A.F. (2010) Preeclampsia and future maternal health. Journal of Hypertension, 28 (7). pp. 1349-1355. ISSN 0263-6352 (doi:10.1097/HJH.0b013e32833a39d0)

Delles, C., Dymott, J.A., Neisius, U., Rocchiccioli, J.P., Bryce, G.J., Moreno Zulategui, M.U., Carty, D.M., Berg, G.A., Hamilton, C.A., and Dominiczak, A.F. (2010) Reduced LDL-cholesterol levels in patients with coronary artery disease are paralelled by improved endothelial function: An observational study in patients from 2003 and 2007. Atherosclerosis, 211 (1). pp. 271-277. ISSN 0021-9150 (doi:10.1016/j.atherosclerosis.2010.01.014)

Delles, C., McBride, M.W., Graham, D., Padmanabhan, S., and Dominiczak, A.F. (2010) Genetics of hypertension: from experimental animals to humans. Biochimica et Biophysica Acta: Molecular Basis of Disease, 1802 (12). pp. 1299-1308. ISSN 0925-4439 (doi:10.1016/j.bbadis.2009.12.006)

Delles, C. et al. (2010) Urinary proteomic diagnosis of coronary artery disease: identification and clinical validation in 623 individuals. Journal of Hypertension, 28 (11). pp. 2316-2322. ISSN 0263-6352 (doi:10.1097/HJH.0b013e32833d81b7)

Dominiczak, A. F. et al. (2010) Systems biology to battle vascular disease. Nephrology, Dialysis, Transplantation, 25 (4). pp. 1019-1022. ISSN 0931-0509 (doi:10.1093/ndt/gfq025)

Fadini, G.P. et al. (2010) Urinary collagen fragments are significantly altered in diabetes: a link to pathophysiology. PLoS ONE, 5 (9). e13051. ISSN 1932-6203 (doi:10.1371/journal.pone.0013051)

Fairley, S., McClure, J., Hanlon, N., Irving, R., McBride, M., Dominiczak, A., and Hunt, E. (2010) Mapping affymetrix microarray probes to the rat genome via a persistent index. International Journal of Knowledge Discovery in Bioinformatics, 1 (1). pp. 48-65. ISSN 1947-9115 (doi:10.4018/jkdb.2010100204)

Graham, D., Koh-Tan, H. H. C., and Dominiczak, A. F. (2010) Reduced renal glutathione S-transferase mu type 1 expression in the stroke-prone spontaneously hypertensive rat. Journal of Hypertension, 28 (3). p. 634. ISSN 0263-6352 (doi:10.1097/HJH.0b013e328336902d)

Hastie, C. et al. (2010) Obesity paradox in a cohort of 4880 consecutive patients undergoing percutaneous coronary intervention. European Heart Journal, 31 (2). pp. 222-226. ISSN 0195-668X (doi:10.1093/eurheartj/ehp317)

Hastie, C. E., Padmanabhan, S., and Dominiczak, A. F. (2010) Genome-wide association studies of hypertension: light at the end of the tunnel. International Journal of Hypertension, 2010 (509581). ISSN 2090-0384 (doi:10.4061/2010/509581)

Lango Allen, H. et al. (2010) Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature, 467 (7317). pp. 832-838. ISSN 0028-0836 (doi:10.1038/nature09410)

Lindgren, C.M. et al. (2010) Genome-wide association scan meta-analysis identifies three loci influencing adiposity and fat distribution. PLoS Genetics, 6 (4). e1000508. ISSN 1553-7390 (doi:10.1371/journal.pgen.1000508)

Liu, J. Z. et al. (2010) Meta-analysis and imputation refines the association of 15q25 with smoking quantity. Nature Genetics, 42 (5). pp. 436-440. ISSN 1061-4036 (doi:10.1038/ng.572)

Luciano, M. et al. (2010) Shared genetic aetiology between cognitive ability and cardiovascular disease risk factors: Generation Scotland's Scottish family health study. Intelligence, 38 (3). pp. 304-313. ISSN 0160-2896 (doi:10.1016/j.intell.2010.03.002)

McCabe, C., Gallagher, L., Macrae, I.M., Gsell, W., Graham, D., and Dominiczak, A.F. (2010) Response to letter by Yao (Differences in the evolution of the ischemic penumbra in stroke-prone spontaneously hypertensive and Wistar-Kyoto rats). Stroke, 41 (4). E198-E199. ISSN 0039-2499 (doi:10.1161/STROKEAHA.109.575704)

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Delles, C., Neisius, U., Dymott, J., Carty, D., Rocchiccioli, J., Bryce, G., Berg, G., Hamilton, C., and Dominiczak, A. (2008) Strategies to target cholesterol levels lead to improved endothelial function in patients with coronary artery disease (CAD). Journal of Hypertension, 26 . S325-S325. ISSN 0263-6352

Dymott, J.A., Chow, C., Rocchiccioli, J.P., Berg, G.A., Cherry, A.K.L., Delles, C., Hamilton, C.A., and Dominiczak, A.F. (2008) Endothelial function in patients undergoing coronary artery by-pass grafting is improved in patients in 2006 compared to 2003. Scottish Medical Journal, 53 (1). p. 57. ISSN 0036-9330

Hastie, C., Padmanabhan, S., Slack, R., Dominiczak, A., and Pell, J. (2008) Factors that predict survival following Percutaneous coronary intervention in patients with and without hypertension. Journal of Hypertension, 26 . S113-S113. ISSN 0263-6352

Miller, W., Graham, D., Douglas, K., MacKenzie, R., and Dominiczak, A. (2008) Metabolic phenotypes in SHRSP and chromosome 2 congenic strains. Journal of Human Hypertension, 22 (10). pp. 736-737. ISSN 0950-9240

Miller, W., Graham, D., Douglas, K., Mackenzie, R., Huynh, N., and Dominiczak, A. (2008) Characterisation of metabolic phenotypes in the SHRSP using chromosome 2 congenic strains. Journal of Hypertension, 26 (Suppl.). S340-S341. ISSN 0263-6352

Moreno, M., Dymott, J., Taurino, C., Berg, G., Carty, D., Mc Culloch, J., Delles, C., and Dominiczak, A. (2008) Whole blood and mononuclear cell superoxide generation are increased in patients with coronary artery disease. Journal of Hypertension, 26 . S308-S308.

Moreno, M., Dymott, J., Taurino, C., Carty, D., Mc Culloch, J., Delles, C., and Dominiczak, A. (2008) Exercise attenuates superoxide release in whole blood and mononuclear cells in patients with coronary artery disease. Journal of Hypertension, 26 . S320-S320.

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Tian, T., McBride, M.W., Graham, D., Touyz, R., and Dominiczak, A.F. (2008) A systems biology approach for the sphingosine-1-phosphate signal transduction in vascular smooth muscle cell. Journal of Hypertension, 26 (Suppl.). S148-S148. ISSN 0263-6352

Tonyz, R., Aranha, A., Yogi, A., Graham, D., McBride, M., Callera, G., Montezano, A., Coimbra, T., and Dominiczak, A. (2008) Increased vascular sphingosine-1-phosphate signaling in SHRSP is due to post-receptor mechanisms. Journal of Hypertension, 26 (Suppl.). S329-S329. ISSN 0263-6352

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Al Benna, S., Hamilton, C.A., McClure, J.D., Rogers, P.N., Berg, G.A., Ford, I., Delles, C., and Dominiczak, A.F. (2006) Low-density lipoprotein cholesterol determines oxidative stress and endothelial dysfunction in saphenous veins from patients with coronary artery disease. Arteriosclerosis, Thrombosis and Vascular Biology, 26 . pp. 218-223. ISSN 1079-5642 (doi:10.1161/01.ATV.0000193626.22269.45)

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Hamilton, C., Groves, S., Carswell, H., Brosnan, M., Graham, D., and Dominiczak, A. (2006) Estrogen treatment enhances nitric oxide bioavailability in normotensive but not hypertensive rats. American Journal of Hypertension, 19 . pp. 859-866. (doi:10.1016/j.amjhyper.2006.01.008)

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Brain, N.J.R., and Dominiczak, A.F. (2005) Pharmacogenomics in hypertension: present practicalities and future potential. Journal of Hypertension, 23 (7). pp. 1327-1329. ISSN 0263-6352

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Collison, M., James, D., Graham, D., Holman, G., Connell, J., Dominiczak, A.F., Gould, G., and Salt, I. (2005) Reduced insulin-stimulated GLUT4 bioavailability in stroke-prone spontaneously hypertensive rats. Diabetologia, 48 (3). pp. 539-546. ISSN 0012-186X (doi:10.1007/s00125-005-1674-x)

Dominiczak, A. (2005) Disentangling fetal and maternal susceptibility for pre-eclampsia: a British multicenter candidate-gene study. American Journal of Human Genetics, 77 (1). pp. 127-131. ISSN 0002-9297 (doi:10.1086/431245)

Dominiczak, A. F., Graham, D., McBride, M. W., Brain, N. J.R., Lee, W. K., Charchar, F. J., Tomaszewski, M., Delles, C., and Hamilton, C. A. (2005) Corcoran Lecture. Cardiovascular genomics and oxidative stress. Hypertension, 45 (4). pp. 636-642. ISSN 0194-911X (doi:10.1161/01.HYP.0000154253.53134.09)

Graham, D., McBride, M., Brain, N., and Dominiczak, A. (2005) Congenic/consomic models of hypertension. Methods in Molecular Medicine, 108 . pp. 3-15.

McBride, M. et al. (2005) Reduction of Gstm1 expression in the stroke-prone spontaneously hypertension rat contributes to increased oxidative stress. Hypertension, 45 . pp. 786-792. (doi:10.1161/01.HYP.0000154879.49245.39)

McCallum, R., Hamilton, C., Graham, D., Jardine, E., Connell, J., and Dominiczak, A. (2005) Vascular responses to IGF-I and insulin are impaired in aortae of hypertensive rats. Journal of Hypertension, 23 . pp. 351-358.

McCallum, R., Sainsbury, C., Spiers, A., Dominiczak, A., Petrie, J., Sattar, N., and Connell, J. (2005) Growth hormone replacement reduces C-reactive protein and large-artery stiffness but does not alter endothelial function in patients with adult growth hormone deficiency. Clinical Endocrinology, 62 (4). pp. 473-479. ISSN 0300-0664 (doi:10.1111/j.1365-2265.2005.02245.x)

McGill, J.K., Gallagher, L., Carswell, H.V.O., Irving, E.A., Dominiczak, A.F., and Macrae, I.M. (2005) Impaired functional recovery after stroke in the stroke-prone spontaneously hypertensive rat. Stroke, 36 (1). pp. 135-141. ISSN 0039-2499 (doi:10.1161/01.STR.0000149629.32525.b7)

Miller, W., Brosnan, M., Graham, D., Nicol, C., Morecroft, I., Channon, K., Danilov, S., Reynolds, P., Baker, A., and Dominiczak, A. (2005) Targeting endothelial cells with adenovirus expressing nitric oxide synthase prevents elevation of blood pressure in stroke-prone spontaneously hypertensive rats. Molecular Therapy, 12 . pp. 321-327. (doi:10.1016/j.ymthe.2005.02.025)

Nemoto, K. et al. (2005) No involvement of the nerve growth factor gene locus in hypertension in spontaneously hypertensive rats. Hypertension Research, 28 (2). pp. 155-163. ISSN 0916-9636

Newhouse, S. et al. (2005) Haplotypes of the WNK1 gene associate with blood pressure variation in a severely hypertensive population from the British Genetics of Hypertension study. Human Molecular Genetics, 14 . pp. 1805-1814. (doi:10.1093/hmg/ddi187)

Padmanabhan, S., Munroe, P.B., Brown, M., Clayton, D., Farrall, M., Webster, J., Lathrop, M., Caulfield, M., Dominiczak, A.F., and Connell, J. (2005) Chromosome 2p shows genome wide significant linkage to anti-hypertensive medication response in the British genetics hypertension (BRIGHT) study. Hypertension, 46 (4). p. 886. ISSN 0194-911X

Strahorn, P., Graham, D., Charchar, F., Sattar, N., McBride, M., and Dominiczak, A. (2005) Genetic determinants of metabolic syndrome components in the stroke-prone spontaneously hypertensive rat. Journal of Hypertension, 23 . pp. 2179-2186.

Wallace, C. et al. (2005) Loci on chromosomes 5p and 20q are linked to multiple hypertension phenotypes in the BRItish Genetics of HyperTension (BRIGHT) study. p. 877.

McBride, M.W., Charchar, F.J., Graham, D., Miller, W.H., Strahorn, P., Carr, F.J., and Dominiczak, A.F. (2004) Functional genomics in rodent models of hypertension. Journal of Physiology, 554 . pp. 56-63. ISSN 0022-3751 (doi:10.1113/jphysiol.2003.049361)

Antier, D., Carswell, H., Brosnan, M., Hamilton, C., Macrae, I., Groves, S., Jardine, E., Reid, J., and Dominiczak, A. (2004) Increased levels of superoxide in brains from old female rats. Free Radical Research, 38 . pp. 177-183. (doi:10.1080/10715760310001643294)

Carswell, H.V., Bingham, D., Wallace, K., Nilsen, M., Graham, D.I., Dominiczak, A.F., and Macrae, I.M. (2004) Differential effects of 17beta-estradiol upon stroke damage in stroke prone and normotensive rats. Journal of Cerebral Blood Flow and Metabolism, 24 (3). pp. 298-304. ISSN 0271-678X

Carswell, H., Bingham, D., Wallace, K., Nilsen, M., Graham, D., Dominiczak, A., and Macrae, I. (2004) Differential effects of 17 beta-estradiol upon stroke damage in stroke prone and normotensive rats. Journal of Cerebral Blood Flow and Metabolism, 24 . pp. 298-304. (doi:10.1097/01.WCB.0000112322.75217.FD)

Charchar, F., Padmanabhan, S., Anderson, N.H., Tomaszewski, M., Upton, M.N., McConnachie, A., Connell, J.M., Watt, G.C.M., Dominiczak, A.F., and Charchar, F.J. (2004) Y chromsome variant is a predictor of cardiovascular mortality. Journal of Hypertension: Supplement, 22 (S1). S58-S59. ISSN 0952-1178

Charchar, F.J., Tomaszewski, M., Lacka, B., Zakrzewski, J., Zukowska-Szczechowska, E., Grzeszczak, W., and Dominiczak, A.F. (2004) Association of the human Y chromosome with cholesterol levels in the general population. Arteriosclerosis, Thrombosis and Vascular Biology, 24 . pp. 308-312. ISSN 1079-5642 (doi:10.1161/01.ATV.0000113291.39267.0a)

Dominiczak, A., Brain, N., Charchar, F., McBride, M., Hanlon, N., and Lee, W. (2004) Genetics of hypertension: Lessons learnt from Mendelian and polygenic syndromes. Clinical and Experimental Hypertension, 26 . pp. 611-620. (doi:10.1081/CEH-200031939)

Graham, D., Hamilton, C., Beattie, E., Spiers, A., and Dominiczak, A. (2004) Comparison of the effects of omapatrilat and irbesartan hydrochlorothiazide on endothelial function and cardiac hypertrophy in the stroke-prone spontaneously hypertensive rat: sex differences. Journal of Hypertension, 22 (2). pp. 329-337. ISSN 0263-6352 (doi:10.1097/01.hjh.0000098240.58662.93)

Graham, D., Hamilton, C., Beattie, E., Spiers, A., and Dominiczak, A.F. (2004) Comparison of the effects of omapatrilat and irbesartan/hydrochlorothiazide on endothelial function and cardiac hypertrophy in the stroke-prone spontaneously hypertensive rat: sex differences. Journal of Hypertension, 22 (2). pp. 329-337. ISSN 0263-6352

Hamilton, C., Miller, W., Al Benna, S., Brosnan, M., Drummond, R., McBride, M., and Dominiczak, A. (2004) Strategies to reduce oxidative stress in cardiovascular disease. Clinical Science, 106 . pp. 219-234. (doi:10.1042/CS20030379)

Hunt, E., Hanlon, N., Leader, D.P., Bryce, H., and Dominiczak, A.F. (2004) The visual language of synteny. OMICS: A Journal of Integrative Biology, 8 . pp. 289-305.

Kuznetsova, T. et al. (2004) Relationship between left ventricular mass and the ACE D/I polymorphism varies according to sodium intake. Journal of Hypertension, 22 (2). pp. 287-295. ISSN 0263-6352

Newhouse, S. et al. (2004) No association of the WNK1 gene with essential hypertension in the MRC BRIGHT study. Journal of Hypertension, 22 . S212-S212.

Padmanabhan, S., Connell, J.M.C., Dominiczak, A.F., Inglis, G., Macfarlane, P.W., and Watt, G. (2004) Heritability and genetic determinants of electrocardiographic measures of left ventricular mass - a two generation family study. Journal of Hypertension: Supplement, 22 (S1). S180-S181. ISSN 0952-1178

Tomaszewski, M., Charchar, F., Crawford, L., Zukowska-Sczechowska, E., Grzeszczak, W., Sattar, N., and Dominiczak, A. (2004) Serum C-reactive protein and lipids in ultra-marathon runners. American Journal of Cardiology, 94 . pp. 125-126. (doi:10.1016/j.amjcard.2004.03.043)

Tomaszewski, M., Charchar, F., Lacka, B., Pesonen, U., Wang, W., Zukowska-Szczechowska, E., Grzeszczak, W., and Dominiczak, A. (2004) Epistatic interaction between beta2-adrenergic receptor and neuropeptide Y genes influences LDL-cholesterol in hypertension. pp. 689-694.

Tomaszewski, M., Charchar, F., Lacka, B., Pesonen, U., Wang, W., Zukowska-Szczechowska, E., Grzeszczak, W., and Dominiczak, A. (2004) Epistatic interaction between beta(2)-adrenergic receptor and neuropeptide Y genes influences LDL-cholesterol in hypertension. Hypertension, 44 . pp. 689-694. (doi:10.1161/01.HYP.0000143844.81979.61)

Stanton, T., Payne, J.R., Montgomery, H.E., Watt, G., Dominiczak, A.F., Jardine, A.G., and Connell, J.M. (2003) Genetic determinants of left ventricular mass: the role of beta-1 adrenoceptor variation in normal, athletic, and disease populations. Journal of the American College of Cardiology, 41 (6 (S1)). p. 273. ISSN 0735-1097 (doi:10.1016/S0735-1097(03)82282-9)

Brown, M., Cruickshank, J., Dominiczak, A., MacGregor, G., Poulter, N., Russell, G., Thom, S., and Williams, B. (2003) Better blood pressure control: how to combine drugs. Journal of Human Hypertension, 17 . pp. 81-86. (doi:10.1038/sj.jhh.1001511)

Caulfield, M. et al. (2003) Genome-wide mapping of human loci for essential hypertension. Lancet, 361 (9375). pp. 2118-2123. ISSN 0140-6736 (doi:10.1016/S0140-6736(03)13722-1)

Charchar, F., Tomaszewski, M., Strahorn, P., Champagne, B., and Dominiczak, A. (2003) Y is there a risk to being male? Trends in Endocrinology and Metabolism, 14 . pp. 163-168. ISSN 1043-2760 (doi:10.1016/S1043-2760(02)00032-8)

Dominiczak, A.F., and McBride, M.W. (2003) Genetics of common polygenic stroke. Nature Genetics, 35 (2). pp. 116-117.

Izzard, A.S., Graham, D., Burnham, M.P., Heerkens, E.H., Dominiczak, A.F., and Heagerty, A.M. (2003) Myogenic and structural properties of cerebral arteries from the stroke-prone spontaneously hypertensive rat. American Journal of Physiology: Heart and Circulatory Physiology, 285 . H1489-H1494. ISSN 0363-6135 (doi:10.1152/ajpheart.00352.2003)

Khan, I.Y., Taylor, P.D., Dekou, V., Seed, P.T., Lakasing, L., Graham, D., Dominiczak, A.F., Hanson, M.A., and Poston, L. (2003) Gender-linked hypertension in offspring of lard-fed pregnant rats. Hypertension, 41 (1). pp. 168-175. ISSN 0194-911X

Khan, L., Taylor, P., Dekou, V., Seed, P., Lakasing, L., Graham, D., Dominiczak, A., Hanson, M., and Poston, L. (2003) Gender-linked hypertension in offspring of lard-fed pregnant rat. Hypertension, 41 . pp. 168-175. (doi:10.1161/01.HYP.0000047511.97879.FC)

McBride, M., Carr, F., Graham, D., Anderson, N., Clark, J., Lee, W., Charchar, F., Brosnan, M., and Dominiczak, A. (2003) Microarray analysis of rat chromosome 2 congenic strains. Hypertension, 41 . pp. 847-853. (doi:10.1161/01.HYP.0000047103.07205.03)

Pell, J., Smith, G., Dominiczak, A., Cobbe, S., Dobbie, R., McMahon, A., and Ford, I. (2003) Family history of premature death from ischaemic heart disease is associated with an increased risk of delivering a low birth weight baby. Heart, 89 (10). pp. 1249-1250. (doi:10.1136/heart.89.10.1249 )

Stanton, T., Robb, S., Payne, J., Montgomery, H., Watt, G., McDonagh, T., Dominiczak, A., Connell, J., and Dargie, H. (2003) The effect of beta-1 adrenoceptor genetic variation on left ventricular mass. Circulation, 108 (17). p. 180.

Tomaszewski, M., Charchar, F.J., Padmanabhan, S., Zukowska-Szczechowska, E., Grzeszczak, W., and Dominiczak, A.F. (2003) Cardiovascular diseases and G-protein beta 3 subunit gene (GNB3) in the era of genomewide scans. Journal of Human Hypertension, 17 (6). pp. 379-380. ISSN 0950-9240 (doi:10.1038/sj.jhh.1001559)

Tomaszewski, M. et al. (2003) Strikingly low circulating CRP concentrations in ultramarathon runners independent of markers of adiposity - How low can you go? Arteriosclerosis, Thrombosis and Vascular Biology, 23 (9). pp. 1640-1644. ISSN 1079-5642 (doi:10.1161/01.ATV.0000087036.75849.0B)

Ye, P. et al. (2003) Cardiac aldosterone synthase (CYP11B2) gene expression is not increased in the fibrotic heart. p. 635.

Tomaszewski, M. et al. (2002) Essential hypertension and beta(2)-adrenergic receptor gene linkage and association analysis. Hypertension, 40 (3). pp. 286-291. ISSN 0194-911X

Brosnan, M., Hamilton, C., Graham, D., Lygate, C., Jardine, E., and Dominiczak, A. (2002) Irbesartan lowers superoxide levels and increases nitric oxide bioavailability in blood vessels from spontaneously hypertensive stroke-prone rats. Journal of Hypertension, 20 . pp. 281-286.

Carr, F.J., Negrin, C.D., Clark, J.S., Graham, D., McBride, M.W., Anderson, N.W., and Dominiczak, A.F. (2002) Chromosome 2 reciprocal congenic strains to evaluate the effect of the genetic background on blood pressure. Scottish Medical Journal, 47 (1). pp. 7-9. ISSN 0036-9330

Carr, F., McBride, M., Carswell, H., Graham, D., Strahorn, P., Clark, J., Charchar, F., and Dominiczak, A. (2002) Genetic aspects of stroke: Human and experimental studies. Journal of Cerebral Blood Flow and Metabolism, 22 . pp. 767-773.

Caulfield, M. et al. (2002) The MRC British Genetics of Hypertension Study - Genome-wide screen results. Journal of Hypertension, 20 . S7-S7.

Charchar, F.J. et al. (2002) The Y chromosome effect on blood pressure in two European populations. Hypertension, 39 . pp. 353-356. ISSN 0194-911X

Duncan, A., Petrie, J., Brosnan, M., Devlin, A., Bass, R., Charnock-Jones, D., Connell, J., Dominiczak, A., and Lumsden, M. (2002) Is estradiol cardioprotection a nitric oxide-mediated effect? Human Reproduction, 17 (7). pp. 1918-1923. ISSN 0268-1161 (doi:10.1093/humrep/17.7.1918)

Fennell, J., Brosnan, M., Frater, A., Hamilton, C., Alexander, M., Nicklin, S., Heistad, D., Baker, A., and Dominiczak, A. (2002) Adenovirus-mediated overexpression of extracellular superoxide dismutase improves endothelial dysfunction in a rat model of hypertension. Gene Therapy, 9 . pp. 110-117. (doi:10.1038/sj/gt/3301633)

Hamilton, C., Brosnan, M., Al Benna, S., Berg, G., and Dominiczak, A. (2002) NAD(P)H oxidase inhibition improves endothelial function in rat and human blood vessels. Hypertension, 40 (5). pp. 755-762.

Hamilton, C., O'Dowd, G., McIntosh, L., Berg, G., Butler, J., Pathi, V., Williams, R., Reid, J., and Dominiczak, A. (2002) Vasorelaxant properties of isolated human radial arteries: comparison with internal mammary arteries. Atherosclerosis, 160 . pp. 345-353. ISSN 0021-9150

McBride, M., Carswell, H., Graham, D., Carr, F., Charchar, F., Macrae, I., and Dominiczak, A. (2002) Genetic and gender determinants of cerebrovascular disease. Seminars in Nephrology, 22 . pp. 127-134. (doi:10.1053/snep.2002.30213)

McCallum, R.W., Hamilton, C., Graham, D., Jardine, E., Dominiczak, A.F., and Connell, J. (2002) Hypertensive but not normotensive rat arteries display impaired nitric oxide-dependant vasodilatation to insulin-like growth factor and insulin. Journal of Hypertension, 20 . S284-S284.

McCallum, R., Petrie, J., Dominiczak, A., and Connell, J. (2002) Growth hormone deficiency and vascular risk. Clinical Endocrinology, 57 (1). pp. 11-24. ISSN 0300-0664 (doi:10.1046/j.1365-2265.2002.01559.x)

Padmanabhan, S., Padmanabhan, A., Dominiczak, A.F., and Connell, J. (2002) A web-based hypertension genetics resource. Journal of Hypertension, 20 . S24-S24.

Stanton, T., Inglis, G.C., Padmanabhan, S., Dominiczak, A.F., Jardine, A.G., and Connell, J.M. (2002) Variation at the beta-1 adrenoceptor gene locus affects left ventricular mass in renal failure. Journal of Nephrology, 15 (5). pp. 512-518.

Stanton, T., Padmanabhan, S., Payne, J.R., Watt, G., Montgomery, H.E., Jardine, A.G., Dominiczak, A.F., and Connell, J. (2002) The role of beta-1 adrenoceptor variation in determining LV mass in normal, athletic and disease populations. Hypertension, 40 (4). p. 576. ISSN 0194-911X

Berry, C., Anderson, N., Kirk, A., Dominiczak, A., and McMurray, J. (2001) Renin angiotensin system inhibition is associated with reduced free radical concentrations in arteries of patients with coronary heart disease. Heart, 86 (2). pp. 217-220.

Berry, C., Brosnan, M., Alexander, M., Hamilton, C., McMurray, J., and Dominiczak, A.F. (2001) Mechanisms of oxidative free radical generation in human arteries. Clinical Science , 101 (2). 7P.

Berry, C., Brosnan, M., Fennell, J., Hamilton, C., and Dominiczak, A. (2001) Oxidative stress and vascular damage in hypertension. Current Opinion in Nephrology and Hypertension, 10 . pp. 247-255.

Berry, C., Touyz, R., Dominiczak, A.F., Webb, R.C., and Johns, D.G. (2001) Angiotensin receptors: signaling, vascular pathophysiology, and interactions with ceramide. American Journal of Physiology: Heart and Circulatory Physiology, 281 . H2337-H2365. ISSN 0363-6135

Cohuet, G., Challande, P., Osborne-Pellegrin, M., Arribas, S., Dominiczak, A., Louis, H., Laurent, S., and Lacolley, P. (2001) Mechanical strength of the isolated carotid artery in SHR. Hypertension, 38 . pp. 1167-1171.

De Lange, R.P., Burr, K., Clark, J.S., Negrin, C.D., Brosnan, M.J., St Clair, D.M., Dominiczak, A.F., and Shaw, D.J. (2001) Mapping and sequencing rat dishevelled-1: a candidate gene for cerebral ischaemic insult in a rat model of stroke. Neurogenetics, 3 (2). pp. 99-106.

Dorrance, A., Graham, D., Webb, R., Fraser, R., and Dominiczak, A. (2001) Increased membrane sphingomyelin and arachidonic acid in stroke-prone spontaneously hypertensive rats. American Journal of Hypertension, 14 . pp. 1149-1153.

Hamilton, C.A., McPhaden, A.R., Berg, G., Pathi, V., and Dominiczak, A.F. (2001) Is hydrogen peroxide an EDHF in human radial arteries? American Journal of Physiology: Heart and Circulatory Physiology, 280 . H2451-H2455. ISSN 0363-6135

Hamilton, C., Brosnan, M., McIntyre, M., Graham, D., and Dominiczak, A. (2001) Superoxide excess in hypertension and aging - A common cause of endothelial dysfunction. Hypertension, 37 . pp. 529-534.

James, D.J., Cairns, F., Salt, I.P., Murphy, G.J., Dominiczak, A.F., Connell, J.M.C., and Gould, G.W. (2001) Skeletal muscle of stroke-prone spontaneously hypertensive rats exhibits reduced insulin-stimulated glucose transport and elevated levels of caveolin and flotillin. Diabetes, 50 (9). pp. 2148-2156. ISSN 0012-1797 (doi:10.2337/diabetes.50.9.2148 )

Jamieson, A., Ingham, D.G., Dominiczak, A.F., and Connell, J.M. (2001) Not the usual cause of superior vena cava obstruction. Scottish Medical Journal, 46 (2). pp. 51-52. ISSN 0036-9330

Knight, J. et al. (2001) No support for linkage of chromosome 17(q21-24) to Essential Hypertension in the MRC British Genetics of Hypertension (MRC BRIGHT) Study. American Journal of Human Genetics, 69 (4). p. 559.

MacKay, A., Hamilton, C., McArthur, K., Berg, G., Tropeano, A., Boutouyrie, P., Reid, J., and Dominiczak, A. (2001) Radial artery hypertrophy occurs in coronary atherosclerosis and is independent of blood pressure. Clinical Science, 100 . pp. 509-516.

MacKenzie, C.J., Wakefield, J.M., Cairns, F., Dominiczak, A.F., and Gould, G.W. (2001) Regulation of glucose transport in aortic smooth muscle cells by cAMP and cGMP. Biochemical Journal, 353 . pp. 513-519. ISSN 0264-6021

Marks, L., Carswell, H., Peters, E., Graham, D., Patterson, J., Dominiczak, A., and Macrae, I. (2001) Characterization of the microglial response to cerebral ischemia in the stroke-prone spontaneously hypertensive rat. Hypertension, 38 . pp. 116-122.

McCallum, R., Hamilton, C., Graham, D., Jardine, E., Connell, J., and Dominiczak, A. F. (2001) Insulin-like growth factor acts as a NO-dependant vasodilator in normotensive but not hypertensive rat arteries. p. 968.

Negrin, C., McBride, M., Carswell, H., Graham, D., Carr, F., Clark, J., Jeffs, B., Anderson, N., Macrae, I., and Dominiczak, A. (2001) Reciprocal consomic strains to evaluate Y chromosome effects. Hypertension, 37 . pp. 391-397.

Nicklin, S., Reynolds, P., Brosnan, M., White, S., Curiel, D., Dominiczak, A., and Baker, A. (2001) Analysis of cell-specific promoters for viral gene therapy targeted at the vascular endothelium. Hypertension, 38 . pp. 65-70.

Nicklin, S., Von Seggern, D., Work, L., Pek, D., Dominiczak, A., Nemerow, G., and Baker, A. (2001) Ablating adenovirus type 5 fiber-CAR binding and HI loop insertion of the SIGYPLP peptide generate an endothelial cell-selective adenovirus. Molecular Therapy, 4 (6). pp. 534-542. ISSN 1525-0016 (doi:10.1006/mthe.2001.0489)

Petrie, J., Collison, M., Connell, J., Gould, G., and Dominiczak, A. (2001) CD36 deficiency and insulin resistance. Lancet, 358 (9277). pp. 242-243. ISSN 0140-6736 (doi:10.1016/S0140-6736(01)05428-9)

Stanton, T., Jardine, A. G., Dominiczak, A. F., and Connell, J. (2001) Genetic determinants of left ventricular mass: The role of beta-1 adrenoceptor variation. Circulation, 104 (17). p. 197. ISSN 0009-7322

Zicha, J., Negrin, C., Dobesova, Z., Carr, F., Vokurkova, M., McBride, M., Kunes, J., and Dominiczak, A. (2001) Altered Na+-K+ pump activity and plasma lipids in salt-hypertensive Dahl rats: relationship to Atp1a1 gene. Physiol Genomics, 6 (2). pp. 99-104.

Caulfield, M. et al. (2000) A new tool for checks of data precision within the MRC British genetics of hypertension study. Journal of Hypertension, 18 . S180-S180.

Collison, M., Campbell, I., Salt, I., Dominiczak, A., Connell, J., Lyall, H., and Gould, G. (2000) Sex hormones induce insulin resistance in 3T3-L1 adipocytes by reducing cellular content of IRS proteins. Diabetologia, 43 (11). pp. 1374-1380. ISSN 0012-186X (doi:10.1007/s001250051541)

Collison, M., Glazier, A., Graham, D., Morton, J., Dominiczak, M., Aitman, T., Connell, J., Gould, G., and Dominiczak, A. F. (2000) Cd36 and molecular mechanisms of insulin resistance in the stroke-prone spontaneously hypertensive rat. Diabetes, 49 (12). pp. 2222-2226.

Graham, D., Collison, M., Glazier, A., Morton, J., Aitman, T., Connell, J., Gouid, G., and Dominiczak, A. F. (2000) Cd36 gene and molecular mechanisms in insulin resistance in the SHRSP. Journal of Hypertension, 18 . S173-S173.

Munroe, P. et al. (2000) Analysis of the angiotensinogen gene in the MRC British genetics of Hypertension study. American Journal of Human Genetics, 67 (4). p. 304.

Dominiczak, A., Jeffs, B., and Connell, J. (1998) New genetic concepts in hypertensive cardiovascular disease. Current Opinion in Cardiology, 13 (5). pp. 304-311.

Jeffs, B., Clark, J.S., Anderson, N.H., Gratton, J., Brosnan, M.J., Gauguier, D., Reid, J.L., Macrae, I.M., and Dominiczak, A.F. (1997) Sensitivity to cerebral ischaemic insult in a rat model of stroke is determined by a single genetic locus. Nature Genetics, 16 (4). pp. 364-367. ISSN 1061-4036 (doi:10.1038/ng0897-364)

Harden, P., MacLeod, M., Rodger, R., Baxter, G., Connell, J., Dominiczak, A., Junor, B., Briggs, J., and Moss, J. (1997) Effect of renal-artery stenting on progression of renovascular renal failure. Lancet, 349 (9059). pp. 1133-1136.

MacLeod, M., Taylor, A., Baxter, G., Harden, P., Briggs, D., Moss, J., Semple, P., Connell, J., and Dominiczak, A. (1995) Renal artery stenosis managed by Palmaz stent insertion: Technical and clinical outcome. Journal of Hypertension, 13 (12). pp. 1791-1795.

MacLeod, M., Connell, J., Harden, P., Briggs, J., Moss, J., and Dominiczak, A. (1995) Transluminal Vascular Stents for Ostial Atherosclerotic Renal-Artery Stenosis. Lancet, 346 (8982). pp. 1109-1110.

O'Connell, J., Dominiczak, A., Isles, C., McLellan, A., Davidson, G., Gray, C., and Connell, J. (1990) A Comparison of Calcium Pentagastrin and Trh Tests in Screening for Medullary Carcinoma of the Thyroid in Men-Iia. Clinical Endocrinology, 32 (4). pp. 417-423. ISSN 0300-0664 (doi:10.1111/j.1365-2265.1990.tb00881.x)

Book Section

Padmanabhan, S., Caulfield, M., and Dominiczak, A. F. (2014) Genetic basis of blood pressure and hypertension. In: Mancia, G., Grassi, G. and Redon, J. (eds.) Manual of Hypertension of the European Society of Hypertension, Second Edition. CRC Press , Boca Raton, FL, pp. 115-128. ISBN 9781841849973

Padmanabhan, S., and Dominiczak, A. F. (2012) Genetics and hypertension: which information for clinical practice. In: Berbari, A. E. and Mancia, G. (eds.) Special Issues in Hypertension. Springer Milan, Milan, pp. 439-452. ISBN 9788847026001

Work, L.M., Dominiczak, A.F., and McBride, M.W. (2009) The genetic basis of stroke: animal models. In: 3rd Report on Stroke: Genetic research in prevention and in cure. Il Pensiero Scientifico Editore, pp. 219-40.

Miller, W.H., Nicklin, S.A., Baker, A.H., and Dominiczak, A. (2005) Gene transfer and the cardiovascular system. In: Raizada, M.K., Paton, J.F.R., Kasparov, S. and Katovich, M.J. (eds.) Cardiovascular Genomics. Series: Contemporary cardiology . Humana Press, Totowa, NJ, USA, pp. 175-196. ISBN 9781588294005

Conference Proceedings

Sinnott, R.O. et al. (2004) Grid services supporting the usage of secure federated, distributed biomedical data. In: Proceedings of UK e-Science All Hands Meeting, 31 Aug - 3 Sept 2004, Nottingham, UK.

This list was generated on Mon Sep 15 14:59:36 2014 BST.

Grants and Awards listed are those received whilst working with the University of Glasgow.

  • Investigation of Osteopontin as a candidate gene for left ventricular hypertrophy
    British Heart Foundation
    2014 - 2017
     
  • Priming Innovative Translational Research - The University of Glasgow CiC Programme
    Medical Research Council
    2014 - 2015
     
  • Capital Funding for South Glasgow Hospital
    Scottish Executive Health Department
    2014 - 2014
     
  • Stratified Medicine and Imaging
    European Regional Development Fund
    2014 - 2015
     
  • Glasgow Cancer Research UK Centre (CORE)
    Cancer Research UK
    2013 - 2014
     
  • Funding Schemes
    Wellcome Trust
    2013 - 2014
     
  • Institutional Strategic Support Fund (ISSF)
    Wellcome Trust
    2013 - 2014
     
  • Genetic, molecular and functional dissection of a novel pathway for hypertension: Uromodulin, renal function, sodium homeostasis and blood pressure.
    British Heart Foundation
    2013 - 2016
     
  • Wolfson Research Merit Award
    Royal Society
    2013 - 2018
     
  • The Stratified Medicine Scotland Innovation Centre
    Scottish Funding Council
    2013 - 2017
     
  • The Stratified Medicine Scotland Innovation Centre
    Scottish Funding Council
    2013 - 2018
     
  • The Stratified Medicine Scotland Innovation Centre
    Scottish Funding Council
    2013 - 2018
     
  • The Stratified Medicine Scotland Innovation Centre
    Scottish Funding Council
    2013 - 2018
     
  • The Stratified Medicine Scotland Innovation Centre
    Scottish Funding Council
    2013 - 2018
     
  • Glasgow Cancer Research UK Centre (CORE)
    Cancer Research UK
    2012 - 2013
     
  • Institutional Strategic Support Fund (ISSF)
    Wellcome Trust
    2012 - 2014
     
  • Cardiovascular consequences of preeclampsia in women from the Generation Scotland: Scottish Family Health Study.
    Scottish Executive Health Department
    2012 - 2014
     
  • The mitochondrial-targeted antioxidant, MitoQ10: a novel therapeutic agent for cardiovascular disease.
    British Heart Foundation
    2012 - 2012
     
  • EU-MASCARA - Biomarkers for Cardiovascular Disease
    European Commission
    2011 - 2015
     
  • InterPregGen
    European Commission
    2011 - 2016
     
  • Integrated Health - Polyomics and Systems Biomedicine (ISSF Bid)
    Wellcome Trust
    2011 - 2014
     
  • SAHSC Industry Support Programme
    East Scotland European Partnership
    2011 - 2014
     
  • SAHSC Industry Support Programme
    University of Glasgow
    2011 - 2014
     
  • MRes Pathology Students
    Cancer Research UK
    2010 - 2015
     
  • Glasgow Cancer Research UK Centre (CORE)
    Cancer Research UK
    2010 - 2012
     
  • Euratrans
    European Commission
    2010 - 2014
     
  • Practicum - ITE
    Scottish Executive - Teachers Division
    2010 - 2012
     
  • Dissecting the mechanism of action of the novel renin angiotensin hormone angiotensin1-9
    MRC
    2010 - 2013
     
  • Strategic Recruitment
    MRC
    2010 - 2013
     
  • Interrogation and manipulation of miRNA in acute vascular injury
    British Heart Foundation
    2010 - 2014
     
  • DPFS Resource Request (University of Glasgow)
    MRC
    2009 - 2011
     
  • Researcher Exchange from Faculdade de Medicina de Ribeirao Preto, Brazil
    British Council - Manchester
    2009 - 2009
     
  • 3 Tesla Cardiac Magnetic Resonance Imaging Facility at the BHF Glasgow Cardiovascular Research Centre
    British Heart Foundation
    2008 - 2009
     
  • Collaborative strategy for a definitive genome scan in essential hypertension: high fidelity phenotyping and "hypercontrols"
    British Heart Foundation
    2008 - 2011
     
  • A combined approach targeting oxidative stress and apoptosis in stroke
    British Heart Foundation
    2008 - 2012
     
  • Genomics and proteomics of hypertension and its vascular complications: the pathwayomic strategies.
    British Heart Foundation
    2008 - 2011
     
  • Assessment of endothelial function in pregnancy: evaluation of a non-invasive method to analyse flow-mediated vasodilation
    NHS Greater Glasgow & Clyde West Research Endowment Fund
    2008 - 2010
     
  • QTL [Quantitative Trait Locus] Mapping using a rat heterogeneous stock
    Wellcome Trust
    2008 - 2011
     
  • High throughput collaborative analysis of cardiovascular genes in 6000 hypertensives and 6000 controls
    British Heart Foundation
    2008 - 2009
     
  • BRIGHT study - early results and future prospects
    MRC
    2007 - 2008
     
  • Does ACE2 have a protective role in the heart? Systematic analysis of ACE2 in a disease model
    British Heart Foundation
    2007 - 2010
     
  • Biomarkers for battling chronic diseases
    Scottish Funding Council
    2007 - 2012
     
  • Variation in promoter function in CYP11B2 and regulation of aldosterone secretion in cardiovascular disease
    MRC
    2007 - 2010
     
  • VisGenome: visualisation of single and comparative genome representations
    Wellcome Trust
    2007 - 2008
     
  • Does variation in response to oral antiplatelet therapy influence outcome in patients undergoing PCI [Percutaneous Coronary Intervention]?
    NHS Greater Glasgow & Clyde, Endowment Funds Office
    2007 - 2007
     
  • Strategic Partnership Equipment Grant
    MRC
    2007 - 2007
     
  • Characterising the ischaemic penumbra in the SIIRSP and WKY following focal cerebral ischaemia
    Neurosciences Foundation
    2006 - 2007
     
  • InGenious HyperCare - Integrating Genomics, Clinical Research and Care in Hypertension
    European Commission
    2006 - 2010
     
  • Hydralazine in heart failure - a study of the mechanisms of action in human blood vessels
    British Heart Foundation
    2006 - 2009
     
  • Research Councils UK academic fellowships - adrenal and extra-adrenal production of corticosteroids
    EPSRC
    2006 - 2011
     
  • EURATools - European Rat Tools for Functional Genomics
    European Commission
    2006 - 2010
     
  • Acidic fibroblast growth factor gene and human hypertension - from positional cloning to functional studies
    Scottish Executive Health Department
    2005 - 2006
     
  • Targeted gene therapy for cardiovascular disease
    MRC
    2005 - 2008
     
  • Endothelial Repair:Relationships with Human Coronary Atheroma in Vivo
    British Heart Foundation
    2005 - 2006
     
  • BRIGHT study - early results and future prospects
    MRC
    2005 - 2010
     
  • Generation Scotland
    Scottish Executive Health Department
    2005 - 2011
     
  • Sustained gene delivery in vivo using vascular-targeted AAV vectors
    British Heart Foundation
    2005 - 2008
     
  • High Fidelity Phenotyping combined with genomics, proteomics and metabonomics close to the patient
    British Heart Foundation
    2004 - 2008
     
  • Adipocyte lipolysis as a candidate pathway in the pathogenesis of pre-eclampsia
    British Heart Foundation
    2004 - 2008
     
  • Functional genomic analysis of the glutathione-S-transferase mu type 1, positional candidate gene for hypertension
    British Heart Foundation
    2004 - 2007
     
  • Genetic Health in the 21st Century Project
    Scottish Higher Education Funding Council
    2004 - 2009
     
  • Development of systemic gene delivery to the kidney
    Kidney Research UK
    2003 - 2005
     
  • Development and evaluation of novel adeno-associated viral vectors for long term gene therapy
    MRC
    2003 - 2006
     
  • Development of a novel adenovirus-based, targetable vector for selective in vivo gene delivery
    British Heart Foundation
    2003 - 2005
     
  • Genetic determinants of hypertension and its vascular complications: from positional candidate genes to vascular gene transfer strategies
    British Heart Foundation
    2003 - 2008
     
  • The British genetics of hypertension study - application to enhance TDT and control recruitment for fine mapping genes for hypertension
    British Heart Foundation
    2003 - 2005
     
  • The Y Chromosome and Genetic Hypertension
    North Glasgow University Hospitals
    2002 - 2005
     
  • Cardiovascular Functional genomics - Translating experimental work to human disease
    Wellcome Trust
    2002 - 2009
     
  • Y chromosome B2-adrenergic receptor gene and cardiovascular traits from intermediate phenotypes to gene-gene interactions
    Wellcome Trust
    2002 - 2005
     
  • BHF Chair
    British Heart Foundation
    2000 - 2014
     
  • Scottish Centre for Research into e-Science Data, Information and Knowledge Transformation (eDIKT)
    Scottish Higher Education Funding Council
    2000 - 2008
     

Editorial Board

  • 2012 - ongoing: Hypertension - Editor in Chief
  • 2011 - ongoing: Global Heart - Editorial Board
  • 2009 - ongoing: The Asia-Pacific Journal of General Practice - Editorial Board
  • 2009 - 2011: Journal of Hypertension - Associate Editor
  • 2006 - ongoing: Internal and Emergency Medicine - Editorial Board
  • 2006 - ongoing: Journal of the American Society of Hypertension - Editorial Board
  • 2006 - ongoing: American Journal of Hypertension - Editorial Board
  • 2005 - 2007: Faculty of 1000 Biology - Editorial Board
  • 2004 - 2008: Clinical Science - Editor-in-Chief
  • 2004 - ongoing: Current Hypertension Reviews - Editorial Board
  • 2004 - ongoing: Cell Metabolism - Editorial Board
  • 2001 - 2010: Journal of Molecular Medicine - Editorial Board
  • 2001 - ongoing: Blood Pressure - Editorial Board
  • 2000 - 2003: Clinical Science - Associate Editor
  • 1999 - 2000: Clinical Science - Rapid Communication Editor
  • 1999 - ongoing: Physiological Genomics - Editorial Board
  • 1998 - ongoing: Hypertension - Editorial Board
  • 1997 - 2008: Clinical Science - Editorial Board
  • 1996 - 1996: Hypertension - Guest Editor -(Genetic Symposium)
  • 1994 - 1997: Journal of Hypertension - Editorial Board

Prizes, Awards and Distinctions

  • 2010: Sackler Foundation - Sackler Fellowship and Lecture
  • 2009: The Royal Philosophical Society of Glasgow - The Graham Lecture and Medal
  • 2008: European Society of Hypertension - Bjorn Folkow Award and Lecture
  • 2007: Lord Provost - The Lord Provost's Special Award for 2006, for the contribution and commitment to the health of Glasgow
  • 2006: Scotswoman of the Year
  • 2005: High Blood Pressure Research Council of Australia - RD Wright Award and Lecture
  • 2005: OBE
  • 2004: American Heart Association - Arthur Corcoran Award and Lecture
  • 2003: Canadian Hypertension Society - Presidential Award and Lecture
  • 2003: Belgian Hypertension Society - The Lecturer of the Year
  • 1990: University of Michigan - Visiting Associate Professor

Professional Learned Society

  • 2003 - ongoing: Royal Society of Edinburgh - FRSE
  • 2001 - ongoing: Academy of Medical Sciences - FMedSci
  • 1996 - ongoing: American Heart Association - International Fellowship of the Council of High Blood Pressure Research of the American Heart Association (F.A.H.A)

Research Fellowship

  • 1993 - 1998: British Heart Foundation - Senior Research Fellowship