Article

Davidson, A.J., King, J.S., and Insall, R.H. (2013) The use of streptavidin conjugates as immunoblot loading controls and mitochondrial markers for use with Dictyostelium discoideum. BioTechniques, 55 (1). pp. 39-41. ISSN 1940-9818 (doi:10.2144/000114054)

Park, L., Thomason, P.A., Zech, T., King, J.S., Veltman, D.M., Carnell, M., Ura, S., Machesky, L.M., and Insall, R.H. (2013) Cyclical Action of the WASH complex: FAM21 and capping protein drive WASH recycling, not initial recruitment. Developmental Cell, 24 (2). pp. 169-181. ISSN 1534-5807 (doi:10.1016/j.devcel.2012.12.014)

Choi, C.-H., Thomason, P.A., Zaki, M., Insall, R.H., and Barber, D.D.L. (2013) Phosphorylation of actin-related protein 2 (Arp2) is required for normal development and cAMP chemotaxis in dictyostelium. Journal of Biological Chemistry, 288 (4). pp. 2464-2474. ISSN 0021-9258 (doi:10.1074/jbc.M112.435313)

Tang, H. et al. (2013) Loss of scar/WAVE complex promotes N-WASP- and FAK-dependent invasion. Current Biology, 23 (2). pp. 107-117. ISSN 0960-9822 (doi:10.1016/j.cub.2012.11.059)

Pakes, N.K., Veltman, D.M., Rivero, F., Nasir, J., Insall, R., and Williams, R.S.B. (2012) The Rac GEF ZizB regulates development, cell motility and cytokinesis in Dictyostelium. Journal of Cell Science, 125 (10). pp. 2457-2465. ISSN 0021-9533 (doi:10.1242/jcs.100966)

Ura, S., Pollitt, A.Y., Veltman, D.M., Morrice, N.A., Machesky, L.M., and Insall, R.H. (2012) Pseudopod growth and evolution during cell movement is controlled through SCAR/WAVE dephosphorylation. Current Biology, 22 (7). pp. 553-561. ISSN 0960-9822 (doi:10.1016/j.cub.2012.02.020)

Insall, R. (2012) How a paper on RAC set the standard. Nature Reviews Molecular Cell Biology, 13 (2). p. 66. ISSN 1471-0072 (doi:10.1038/nrm3277)

Spence, H.J., Timpson, P., Tang, H.R., Insall, R.H., and Machesky, L.M. (2012) Scar/WAVE3 contributes to motility and plasticity of lamellipodial dynamics but not invasion in three dimensions. Biochemical Journal, 448 (1). pp. 35-42. ISSN 0264-6021 (doi:10.1042/BJ20112206)

Yu, X. et al. (2012) N-WASP coordinates the delivery and F-actin-mediated capture of MT1-MMP at invasive pseudopods. Journal of Cell Biology, 199 (3). pp. 527-544. ISSN 0021-9525 (doi:10.1083/jcb.201203025)

King, J.S., Veltman, D.M., and Insall, R.H. (2011) The induction of autophagy by mechanical stress. Autophagy, 7 (12). pp. 1490-1499. ISSN 1554-8627 (doi:10.4161/auto.7.12.17924)

Li, A. et al. (2011) Rac1 drives melanoblast organization during mouse development by orchestrating pseudopod- driven motility and cell-cycle progression. Developmental Cell, 21 (4). pp. 722-734. ISSN 1534-5807 (doi:10.1016/j.devcel.2011.07.008)

Sapey, E., Stockley, J.A., Greenwood, H., Ahmad, A., Bayley, D., Lord, J.M., Insall, R., and Stockley, R.A. (2011) Behavioral and structural differences in migrating peripheral neutrophils from patients with chronic obstructive pulmonary disease. American Journal of Respiratory and Critical Care Medicine, 183 (9). pp. 1176-1186. ISSN 1073-449X (doi:10.1164/rccm.201008-1285OC)

Carnell, M., Zech, T., Calaminus, S.D., Ura, S., Hagedorn, M., Johnston, S.A., May, R.C., Soldati, T., Machesky, L.M., and Insall, R.H. (2011) Actin polymerization driven by WASH causes V-ATPase retrieval and vesicle neutralization before exocytosis. Journal of Cell Biology, 193 (5). pp. 831-839. ISSN 0021-9525 (doi:10.1083/jcb.201009119)

Carnell, M.J., and Insall, R.H. (2011) Actin on disease – Studying the pathobiology of cell motility using Dictyostelium discoideum. Seminars in Cell and Developmental Biology, 22 (1). pp. 82-88. ISSN 1084-9521 (doi:10.1016/j.semcdb.2010.12.003)

Davidson, Andrew, and Insall, R.H. (2011) Actin-Based Motility: WAVE Regulatory Complex Structure Reopens Old SCARs. Current Biology, 21 (2). R66-R68. ISSN 0960-9822 (doi:10.1016/j.cub.2010.12.001)

Insall, R. (2011) Career postdocs increase scrap heap. Nature, 471 (7340). p. 578. ISSN 0028-0836 (doi:10.1038/471578e)

Insall, R.H. (2011) Dogma bites back – the evidence for branched actin. Trends in Cell Biology, 21 (1). p. 2. ISSN 0962-8924 (doi:10.1016/j.tcb.2010.11.002)

Itakura, A., Verbout, N. G., Phillips, K. G., Insall, R.H., Gailani, D., Tucker, E. I., Gruber, A., and McCarty, O. J. T. (2011) Activated factor XI inhibits chemotaxis of polymorphonuclear leukocytes. Journal of Leukocyte Biology, 90 (5). pp. 923-927. ISSN 0741-5400 (doi:10.1189/jlb.0411182)

Neilson, M.P., Mackenzie, J.A., Webb, S.D., and Insall, R.H. (2011) Modeling Cell Movement and Chemotaxis Using Pseudopod-Based Feedback. SIAM: Journal on Scientific Computing, 33 (3). pp. 1035-1057. ISSN 1064-8275 (doi:10.1137/100788938)

Neilson, M.P., Veltman, D.M., van Haastert, P.J.M., Webb, S.D., Mackenzie, J.A., and Insall, R.H. (2011) Chemotaxis: a feedback-based computational model robustly predicts multiple aspects of real cell behaviour. PLoS Biology, 9 (5). e1000618. ISSN 1544-9173 (doi:10.1371/journal.pbio.1000618)

Veltman, D.W., Auciello, Giulio, Spence, H.J., Machesky, L.M., Rappoport, J.Z., and Insall, R.H. (2011) Functional analysis of DictyosteliumIBARa reveals a conserved role of the I-BAR domain in endocytosis. Biochemical Journal, 436 (1). pp. 45-52. ISSN 0264-6021 (doi:10.1042/BJ20101684)

Zech, T., Calaminus, S.D.J., Caswell, P., Spence, H.J., Carnell, M., Insall, R.H., Norman, J., and Machesky, L.M. (2011) The Arp2/3 activator WASH regulates 5 1-integrin-mediated invasive migration. Journal of Cell Science, 124 (22). pp. 3753-3759. ISSN 0021-9533 (doi:10.1242/jcs.080986)

Gullberg, D., Muinonen-Martin, A.J., Veltman, D.M., Kalna, G., and Insall, R. (2010) An improved chamber for direct visualisation of chemotaxis. PLoS ONE, 5 (12). e15309. ISSN 1932-6203 (doi:10.1371/journal.pone.0015309)

Insall, R.H. (2010) Understanding eukaryotic chemotaxis: a pseudopod-centred view. Nature Reviews Molecular Cell Biology, 11 (6). pp. 453-458. ISSN 1471-0072 (doi:10.1038/nrm2905)

King, J. S., Veltman, D. M., Georgiou, M., Baum, B., and Insall, R. H. (2010) SCAR/WAVE is activated at mitosis and drives myosin-independent cytokinesis. Journal of Cell Science, 123 (13). pp. 2246-2255. ISSN 0021-9533 (doi:10.1242/jcs.063735)

Neilson, M., Mackenzie, J.A., Webb, S.D., and Insall, R. (2010) Use of the parameterised finite element method to robustly and efficiently evolve the edge of a moving cell. Integrative Biology, 2 (11-12). pp. 687-695. ISSN 1757-9694 (doi:10.1039/c0ib00047g)

Veltman, D.M., and Insall, R. H. (2010) WASP Family Proteins: Their Evolution and Its Physiological Implications. Molecular Biology of the Cell, 21 (16). pp. 2880-2893. ISSN 1059-1524 (doi:10.1091/mbc.E10-04-0372)

Insall, RH., and Machesky, L.M. (2009) Actin Dynamics at the Leading Edge: From Simple Machinery to Complex Networks. Developmental Cell, 17 (3). pp. 310-322. ISSN 1534-5807 (doi:10.1016/j.devcel.2009.08.012)

King, J.S., and Insall, R.H. (2009) Chemotaxis: finding the way forward with Dictyostelium. Trends in Cell Biology, 19 (10). pp. 523-530. ISSN 09628924 (doi:10.1016/j.tcb.2009.07.004)

Pollitt, A. Y., and Insall, R. H. (2009) WASP and SCAR/WAVE proteins: the drivers of actin assembly. Journal of Cell Science, 122 (15). pp. 2575-2578. ISSN 0021-9533 (doi:10.1242/jcs.023879)

Pollitt, A.Y., and Insall, R.H. (2009) Loss of Dictyostelium HSPC300 causes a scar-like phenotype and loss of SCAR protein. BMC Cell Biology, 10 (1). p. 13. ISSN 1471-2121 (doi:10.1186/1471-2121-10-13)

Heath, R. J. W., and Insall, R. H. (2008) Dictyostelium MEGAPs: F-BAR domain proteins that regulate motility and membrane tubulation in contractile vacuoles. Journal of Cell Science, 121 (7). pp. 1054-1064. ISSN 0021-9533 (doi:10.1242/jcs.021113)

Heath, R. J. W., and Insall, R. H. (2008) F-BAR domains: multifunctional regulators of membrane curvature. Journal of Cell Science, 121 (12). pp. 1951-1954. ISSN 0021-9533 (doi:10.1242/jcs.023895)

King, J.S., and Insall, R.H. (2008) Chemotaxis: TorC before You Akt…. Current Biology, 18 (18). R864-R866. ISSN 0960-9822 (doi:10.1016/j.cub.2008.07.051)

Pollitt, A.Y., and Insall, R.H. (2008) Abi Mutants in Dictyostelium Reveal Specific Roles for the SCAR/WAVE Complex in Cytokinesis. Current Biology, 18 (3). pp. 203-210. ISSN 09609822 (doi:10.1016/j.cub.2008.01.026)

Insall, R., and Andrew, N. (2007) Chemotaxis in Dictyostelium: how to walk straight using parallel pathways. Current Opinion in Microbiology, 10 (6). pp. 578-581. ISSN 13695274 (doi:10.1016/j.mib.2007.10.004)

Conference Proceedings

Kim, J., and Insall, R. (2009) Position and velocity estimation of cell boundary. In: International Conference on Systems Biology, 30 Aug - 4 Sep 2009, Palo Alto, USA.