Institute of Molecular, Cell and Systems Biology

Prof Julian Dow

Prof Julian A Dow
  • Professor of Molecular and Integrative Physiology (Institute of Molecular Cell and Systems Biology)

telephone: 01413304616
email: Julian.Dow@glasgow.ac.uk


'Molecular Physiology of Ion Transport and Cell Signalling Pathways in Drosophila'

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Jump to: 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006 | 2005 | 2004 | 2003 | 2002 | 2001
Number of items: 65.

2013

Cabrero, P., Richmond, L., Nitabach, M., Davies, S.A., and Dow, J.A.T. (2013) A biogenic amine and a neuropeptide act identically: tyramine signals through calcium in drosophila tubule stellate cells. Proceedings of the Royal Society of London Series B: Biological Sciences, 280 (1757). Art. 20122943. ISSN 0962-8452 (doi:10.1098/rspb.2012.2943)

Efetova, M., Petereit, L., Rosiewicz, K., Overend, G., Haussig, F., Hovemann, B.T., Cabrero, P., Dow, J.A.T., and Schwarzel, M. (2013) Separate roles of PKA and EPAC in renal function unraveled by the optogenetic control of cAMP levels in vivo. Journal of Cell Science, 126 (3). pp. 778-788. ISSN 0021-9533 (doi:10.1242/jcs.114140)

Robinson, S.W., Herzyk, P., Dow, J.A.T., and Leader, D.P. (2013) FlyAtlas: database of gene expression in the tissues of drosophila melanogaster. Nucleic Acids Research, 41 (D1). D744-D750. ISSN 0305-1048 (doi:10.1093/nar/gks1141)

2012

Hirata, T., Cabrero, P., Berkholz, D.S., Bondeson, D.P., Ritman, E.L., Thompson, J.R., Dow, J.A.T., and Romero, M.F. (2012) In vivo Drosophilia genetic model for calcium oxalate nephrolithiasis. American Journal of Physiology: Renal Physiology, 303 (11). F1555-F1562. ISSN 1931-857X (doi:10.1152/ajprenal.00074.2012)

Davies, S.A., Overend, G., Sebastian, S., Cundall, M., Cabrero, P., Dow, J.A.T., and Terhzaz, S. (2012) Immune and stress response 'cross-talk' in the Drosophila Malpighian tubule. Journal of Insect Physiology, 58 (4). pp. 488-497. ISSN 0022-1910 (doi:10.1016/j.jinsphys.2012.01.008)

Dow, J.A.T. (2012) William R. Harvey: an appreciation. Journal of Insect Physiology, 58 (4). pp. 428-430. ISSN 0022-1910 (doi:10.1016/j.jinsphys.2011.09.019)

Hirata, T., Czapar, A., Brin, L., Haritonova, A., Bondeson, D.P., Linser, P., Cabrero, P., Thompson, J., Dow, J.A.T., and Romero, M.F. (2012) Ion and solute transport by Prestin in Drosophila and Anopheles. Journal of Insect Physiology, 58 (4). pp. 563-9. ISSN 0022-1910 (doi:10.1016/j.jinsphys.2012.01.009)

Overend, G., Cabrero, P., Guo, A.X., Sebastian, S., Cundall, M., Armstrong, H., Mertens, I., Schoofs, L., Dow, J.A.T., and Davies, S.-A. (2012) The receptor guanylate cyclase Gyc76C and a peptide ligand, NPLP1-VQQ, modulate the innate immune IMD pathway in response to salt stress. Peptides, 34 (1). pp. 209-218. ISSN 0196-9781 (doi:10.1016/j.peptides.2011.08.019)

Bratty, M.A., Chintapalli, V.R., Dow, J.A.T., Zhang, T., and Watson, D.G. (2012) Metabolomic profiling reveals that Drosophila melanogaster larvae with the y mutation have altered lysine metabolism. FEBS Open Bio, 2 . pp. 217-221. ISSN 2211-5463 (doi:10.1016/j.fob.2012.07.007)

Chintapalli, V., Terhzaz, S., Wang, J., Al Bratty, M., Watson, D.G., Herzyk, P., Davies, S.A., and Dow, J.A.T. (2012) Functional correlates of positional and gender-specific renal asymmetry in Drosophila. PLoS ONE, 7 (4). e32577. ISSN 1932-6203 (doi:10.1371/journal.pone.0032577)

Terhzaz, S., Cabrero, P., Robben, J.H., Radford, J.C., Hudson, B., Milligan, G., Dow, J.A.T., and Davies, S. (2012) Mechanism and function of Drosophila capa GPCR: a desiccation stress-responsive receptor with functional homology to human neuromedinU receptor. PLoS ONE, 7 (1). e29897. ISSN 1932-6203 (doi:10.1371/journal.pone.0029897)

Terhzaz, S., Cabrero, P., Robben, J.H., Radford, J.C., Hudson, B.D., Milligan, G., Dow, J.A.T., and Davies, S.A. (2012) Mechanism and function of drosophila capa GPCR: a desiccation stress-responsive receptor with functional homology to human neuromedinU receptor. PLoS ONE, 7 (1). e29897. ISSN 1932-6203 (doi:10.1371/journal.pone.0029897)

2011

Al Bratty, M., Hobani, Y., Dow, J.A.T., and Watson, D.G. (2011) Metabolomic profiling of the effects of allopurinol on Drosophila melanogaster. Metabolomics, 7 (4). pp. 542-548. ISSN 1573-3882 (doi:10.1007/s11306-011-0275-6)

Dow, J.A.T. (2011) The versatile stellate cell – More than just a space-filler. Journal of Insect Physiology, 58 (4). pp. 467-472. ISSN 0022-1910 (doi:10.1016/j.jinsphys.2011.12.003)

2010

Terhzaz, S., Finlayson, A.J., Stirrat, L., Yang, J.L., Tricoire, H., Woods, D.J., Dow, J.A.T., and Davies, S.A. (2010) Cell-specific inositol 1,4,5 trisphosphate 3-kinase mediates epithelial cell apoptosis in response to oxidative stress in Drosophila. Cellular Signalling, 22 (5). pp. 737-748. ISSN 0898-6568 (doi:10.1016/j.cellsig.2009.12.009)

Terhzaz, S., Cabrero, P., Chintapalli, V.R., Davies, S.A., and Dow, J.A.T. (2010) Mislocalization of mitochondria and compromised renal function and oxidative stress resistance in Drosophila SesB mutants. Physiological Genomics, 41 (1). pp. 33-41. ISSN 1094-8341 (doi:10.1152/physiolgenomics.00147.2009)

Beyenbach, K.W., Skaer, H., and Dow, J.A.T. (2010) The developmental, molecular, and transport biology of Malpighian tubules. Annual Review of Entomology, 55 . pp. 351-374. ISSN 0066-4170 (doi:10.1146/annurev-ento-112408-085512)

Dow, J.A.T., and Romero, M.F. (2010) Drosophila provides rapid modeling of renal development, function, and disease. AJP: Renal Physiology, 299 (6). F1237-F1244. ISSN 0363-6127 (doi:10.1152/ajprenal.00521.2010)

Terhzaz, S., Cabrero, P., Chintapalli, V.R., Davies, S.A., and Dow, J.A.T. (2010) Mislocalization of mitochondria and compromised renal function and oxidative stress resistance in Drosophila SesB mutants. Physiological Genomics, 41 (1). pp. 33-41. ISSN 1094-8341 (doi:10.1152/physiolgenomics.00147.2009)

2009

Kamleh, M.A., Hobani, Y., Dow, J.A.T., Zheng, L., and Watson, D.G. (2009) Towards a platform for the metabonomic profiling of different strains of Drosophila melanogaster using liquid chromatography-Fourier transform mass spectrometry. FEBS Journal, 276 (22). pp. 6798-6809. ISSN 1742-464X (doi:10.1111/j.1742-4658.2009.07397.x)

Davies, S.A., and Dow, J.A.T. (2009) Modulation of epithelial innate immunity by autocrine production of nitric oxide. General and Comparative Endocrinology, 162 (1). pp. 113-121. ISSN 0016-6480 (doi:10.1016/j.ygcen.2008.09.012)

Simons, M. et al. (2009) Electrochemical cues regulate assembly of the Frizzled/Dishevelled complex at the plasma membrane during planar epithelial polarization. Nature Cell Biology, 11 (3). pp. 286-294. ISSN 1465-7392 (doi:10.1038/ncb1836)

Dow, J.A.T. (2009) Insights into the Malpighian tubule from functional genomics. Journal of Experimental Biology, 212 (3). pp. 435-445. ISSN 0022-0949 (doi:10.1242/jeb.024224)

Dow, J.A.T. (2009) Where it all began (nearly). Journal of Experimental Biology, 212 (3). pp. 327-328. ISSN 0022-0949 (doi:10.1242/jeb.021964)

Kettlewell, S., Cabrero, P., Nicklin, S.A., Dow, J.A.T., Davies, S.A., and Smith, G.L. (2009) Changes of intra-mitochondrial Ca2+ in adult ventricular cardiomyocytes examined using a novel fluorescent Ca2+ indicator targeted to mitochondria. Journal of Molecular and Cellular Cardiology, 46 (6). pp. 891-901. ISSN 0022-2828 (doi:10.1016/j.yjmcc.2009.02.016)

Stergiopoulos, K., Cabrero, P., Davies, S.A., and Dow, J.A.T. (2009) Salty dog, an SLC5 symporter, modulates Drosophila response to salt stress. Physiological Genomics, 37 (1). pp. 1-11. ISSN 1094-8341 (doi:10.1152/physiolgenomics.90360.2008)

2008

Kamleh, M.A., Hobani, Y., Dow, J.A.T., and Watson, D.G. (2008) Metabolomic profiling of Drosophila using liquid chromatography Fourier transform mass spectrometry. FEBS Letters, 582 (19). pp. 2916-2922. ISSN 0014-5793 (doi:10.1016/j.febslet.2008.07.029)

Day, J. P., Wang, S.M., Allan, A.K., Kean, L., Davies, S.A., Gray, J.V., and Dow, J.A.T. (2008) Identification of two partners from the bacterial Kef exchanger family for the apical plasma membrane V-ATPase of Metazoa. Journal of Cell Science, 121 (15). pp. 2612-2619. ISSN 0021-9533 (doi:10.1242/jcs.033084)

Evans, J.M., Day, J.P., Cabrero, P., Dow, J.A.T., and Davies, S.A. (2008) A new role for a classical gene: white transports cyclic GMP. Journal of Experimental Biology, 211 . pp. 890-899. ISSN 0022-0949 (doi:10.1242/jeb.014837)

2007

Baker, D.A., Meadows, L.A., Wang, J., Dow, J.A.T., and Russell, S. (2007) Variable sexually dimorphic gene expression in laboratory strains of Drosophila melanogaster. BMC Genomics, 8 . p. 454. ISSN 1471-2164 (doi:10.1186/1471-2164-8-454)

Chintapalli, V.R., Wang, J., and Dow, J.A.T. (2007) Using FlyAtlas to identify better Drosophila melanogaster models of human disease. Nature Genetics, 39 . pp. 715-720. (doi:10.1038/ng2049)

Dow, JAT (2007) Integrative physiology, functional genomics and the phenotype gap: a guide for comparative physiologists. Journal of Experimental Biology, 210 . pp. 1632-1640. (doi:10.1242/jeb.002691)

Dow, JAT (2007) Model organisms and molecular genetics for endocrinology. General and Comparative Endocrinology, 153 . pp. 3-12. ISSN 0016-6480 (doi:10.1016/j.ygcen.2007.01.023)

Yang, J, McCart, C, Woods, DJ, Terhzaz, S, Greenwood, KG, Ffrench-Constant, RH, and Dow, JAT (2007) A Drosophila systems approach to xenobiotic metabolism. Physiological Genomics, 30 . pp. 223-231. ISSN 1094-8341 (doi:10.1152/physiolgenomics.00018.2007)

2006

Du, J., Kean, L., Allan, A.K., Southall, T.D., Davies, S.A., McInerny, C.J., and Dow, J.A.T. (2006) The SzA mutations of the B subunit of the Drosophila vacuolar H+ ATPase identify conserved residues essential for function in fly and yeast. Journal of Cell Science, 119 (12). pp. 2542-2551. ISSN 0021-9533 (doi:10.1242/jcs.02983)

Dow, JAT, and Davies, SA (2006) The Malpighian tubule: Rapid insights from post-genomic biology. Journal of Insect Physiology, 52 . pp. 365-378. ISSN 0022-1910 (doi:10.1016/j.jinsphys.2005.10.007)

Southall, T.D., Terhzaz, S, Cabrero, P, Chintapalli, V.R., Evans, J.M., Dow, J.A.T, and Davies, S.A. (2006) Novel subcellular locations and functions for secretory pathway Ca2+/Mn2+-ATPases. Physiological Genomics, 26 . pp. 35-45. ISSN 1094-8341 (doi:10.1152/physiolgenomics.00038.2006)

Terhzaz, S, Southall, TD, Lilley, KS, Kean, L, Allan, AK, Davies, SA, and Dow, JAT (2006) Differential gel electrophoresis and transgenic mitochondrial calcium reporters demonstrate spatiotemporal filtering in calcium control of mitochondria. Journal of Biological Chemistry, 281 . pp. 18849-18858. ISSN 0021-9258 (doi:10.1074/jbc.M603002200)

2005

Allan, AK, Du, J, Davies, SA, and Dow, JAT (2005) Genome-wide survey of V-ATPase genes in Drosophila reveals a conserved renal phenotype for lethal alleles. Physiological Genomics, 22 . pp. 128-138. ISSN 1094-8341 (doi:10.1152/physiolgenomics.00233.2004)

Day, JP, Dow, JAT, Houslay, MD, and Davies, SA (2005) Cyclic nucleotide phosphodiesterases in Drosophila melanogaster. Biochemical Journal, 388 . pp. 333-342. ISSN 0264-6021 (doi:10.1042/BJ20050057)

Dow, J (2005) Physiology engages with functional genomics - at last. Genome Biology, 6 (8). pp. 3351-3353. (doi:10.1186/gb-2005-6-8-335)

Evans, JM, Allan, AK, Davies, SA, and Dow, JAT (2005) Sulphonylurea sensitivity and enriched expression implicate inward rectifier K+ channels in Drosophila melanogaster renal function. Journal of Experimental Biology, 208 . pp. 3771-3783.

Gilleard, JS, Woods, DJ, and Dow, JAT (2005) Model-organism genomics in veterinary parasite drug-discovery. Trends in Parasitology, 21 . pp. 302-305. (doi:10.1016/j.pt.2005.05.007)

Johnson, EC, Shafer, OT, Trigg, JS, Park, J, Schooley, DA, Dow, JA, and Taghert, PH (2005) A novel diuretic hormone receptor in Drosophila: evidence for conservation of CGRP signaling. Journal of Experimental Biology, 208 . pp. 1239-1246. (doi:10.1242/jeb.01529)

Kaufmann, N, Mathai, JC, Hill, WG, Dow, JAT, Zeidel, ML, and Brodsky, JL (2005) Developmental expression and biophysical characterization of a Drosophila melanogaster aquaporin. American Journal of Physiology: Cell Physiology, 289 . C397-C407. (doi:10.1152/ajpcell.00612.2004)

MacPherson, MR, Pollock, VP, Kean, L, Southall, TD, Giannakou, ME, Broderick, KE, Dow, JAT, Hardie, RC, and Davies, SA (2005) Transient receptor potential-like channels are essential for calcium signaling and fluid transport in a Drosophila epithelium. Genetics, 169 . pp. 1541-1552. (doi:10.1534/genetics.104.035139)

McGettigan, J et al. (2005) Insect renal tubules constitute a cell-autonomous immune system that protects the organism against bacterial infection. Insect Biochemistry and Molecular Biology, 35 . pp. 741-754. (doi:10.1016/j.ibmb.2005.02.017)

2004

Broderick, KE, Kean, L, Dow, JAT, Pyne, NJ, and Davies, SA (2004) Ectopic expression of bovine type 5 phosphodiesterase confers a renal phenotype in Drosophila. Journal of Biological Chemistry, 279 . pp. 8159-8168. ISSN 0021-9258 (doi:10.1074/jbc.M304679200)

Cabrero, P, Pollock, VP, Davies, SA, and Dow, JAT (2004) A conserved domain of alkaline phosphatase expression in the Malpighian tubules of dipteran insects. Journal of Experimental Biology, 207 . pp. 3299-3305. (doi:10.1242/jeb.01156)

MacPherson, MR, Broderick, KE, Graham, S, Day, JP, Houslay, MD, Dow, JAT, and Davies, SA (2004) The dg2 (for) gene confers a renal phenotype in Drosophila by modulation of cGMP-specific phosphodiesterase. Journal of Experimental Biology, 207 . pp. 2769-2776. (doi:10.1242/jeb.01086)

Pollock, VP, McGettigan, J, Cabrero, P, Maudlin, IM, Dow, JAT, and Davies, SA (2004) Conservation of capa peptide-induced nitric oxide signalling in Diptera. Journal of Experimental Biology, 207 . pp. 4135-4145. (doi:10.1242/jeb.01255)

Radford, JHC, Terhzaz, S, Cabrero, P, Davies, SA, and Dow, JAT (2004) Functional characterisation of the Anopheles leucokinins and their cognate G-protein coupled receptor. Journal of Experimental Biology, 207 . pp. 4573-4586. (doi:10.1242/jeb.01317)

Torrie, LS, Radford, JC, Southall, TD, Kean, L, Dinsmore, AJ, Davies, SA, and Dow, JAT (2004) Resolution of the insect ouabain paradox. Proceedings of the National Academy of Sciences of the United States of America, 101 . pp. 13689-13693. (doi:10.1073/pnas.0403087101)

Wang, J, Kean, L, Yang, JL, Allan, AK, Davies, SA, Herzyk, P, and Dow, JAT (2004) Function-informed transcriptome analysis of Drosophila renal tubule. Genome Biology, 5 .

2003

Broderick, KE, MacPherson, MR, Regulski, M, Tully, T, Dow, JAT, and Davies, SA (2003) Interactions between epithelial nitric oxide signaling and phosphodiesterase activity in Drosophila. American Journal of Physiology: Cell Physiology, 285 . C1207-C1218. (doi:10.1152/ajpcell.00123.2003)

Dow, J (2003) The Drosophila genome: the way forward. Briefings in Functional Genomics and Proteomics, 2 (2). pp. 92-93. (doi:10.1093/bfgp%2F2.2.92)

Dow, J (2003) The Drosophila phenotype gap ù and how to close it. Briefings in Functional Genomics and Proteomics, 2 (2). pp. 121-127. (doi:10.1093/bfgp%2F2.2.121)

Dow, JAT, and Davies, SA (2003) Integrative physiology and functional genomics of epithelial function in a genetic model organism. Physiological Reviews, 83 . pp. 687-729. (doi:10.1152/physrev.00035.2002)

Pollock, VP, Radford, JC, Pyne, S, Hasan, G, Dow, JAT, and Davies, SA (2003) norpA and itpr mutants reveal roles for phospholipase C and inositol (1,4,5)-trisphosphate receptor in Drosophila melanogaster renal function. Journal of Experimental Biology, 206 . pp. 901-911. (doi:10.1242/jeb.00189)

2002

Cabrero, P, Radford, JC, Broderick, KE, Costes, L, Veenstra, JA, Spana, EP, Davies, SA, and Dow, JAT (2002) The Dh gene of Drosophila melanogaster encodes a diuretic peptide that acts through cyclic AMP. Journal of Experimental Biology, 205 . pp. 3799-3807.

Kean, L., Cazenave, W., Costes, L., Broderick, K.E., Graham, S., Pollock, V.P., Davies, S.A., Veenstra, J.A., and Dow, J.A.T. (2002) Two nitridergic peptides are encoded by the gene capability in Drosophila melanogaster. American Journal of Physiology: Regulatory Integrative and Comparative Physiology, 282 . R1297-R1307. (doi:10.1152/ajpregu.00584.2001)

Radford, JC, Davies, SA, and Dow, JAT (2002) Systematic G-protein-coupled receptor analysis in Drosophila melanogaster identifies a leucokinin receptor with novel roles. Journal of Biological Chemistry, 277 . pp. 38810-38817. ISSN 0021-9258 (doi:10.1074/jbc.M203694200)

2001

Dow, JAT, and Davies, SA (2001) The Drosophila melanogaster malpighian tubule. Advances in Insect Physiology, 28 . pp. 1-83.

Giannakou, ME, and Dow, JAT (2001) Characterization of the Drosophila melanogaster alkali-metal/proton exchanger (NHE) gene family. Journal of Experimental Biology, 204 . pp. 3703-3716.

MacPherson, MR, Pollock, VP, Broderick, KE, Kean, L, OConnell, FC, Dow, JAT, and Davies, SA (2001) Model organisms: New insights into ion channel and transporter function. L-type calcium channels regulate epithelial fluid transport in Drosophila melanogaster. American Journal of Physiology: Cell Physiology, 280 . C394-C407.

This list was generated on Wed Jun 19 13:43:19 2013 BST.
Jump to: Article
Number of items: 65.

Article

Cabrero, P., Richmond, L., Nitabach, M., Davies, S.A., and Dow, J.A.T. (2013) A biogenic amine and a neuropeptide act identically: tyramine signals through calcium in drosophila tubule stellate cells. Proceedings of the Royal Society of London Series B: Biological Sciences, 280 (1757). Art. 20122943. ISSN 0962-8452 (doi:10.1098/rspb.2012.2943)

Efetova, M., Petereit, L., Rosiewicz, K., Overend, G., Haussig, F., Hovemann, B.T., Cabrero, P., Dow, J.A.T., and Schwarzel, M. (2013) Separate roles of PKA and EPAC in renal function unraveled by the optogenetic control of cAMP levels in vivo. Journal of Cell Science, 126 (3). pp. 778-788. ISSN 0021-9533 (doi:10.1242/jcs.114140)

Robinson, S.W., Herzyk, P., Dow, J.A.T., and Leader, D.P. (2013) FlyAtlas: database of gene expression in the tissues of drosophila melanogaster. Nucleic Acids Research, 41 (D1). D744-D750. ISSN 0305-1048 (doi:10.1093/nar/gks1141)

Hirata, T., Cabrero, P., Berkholz, D.S., Bondeson, D.P., Ritman, E.L., Thompson, J.R., Dow, J.A.T., and Romero, M.F. (2012) In vivo Drosophilia genetic model for calcium oxalate nephrolithiasis. American Journal of Physiology: Renal Physiology, 303 (11). F1555-F1562. ISSN 1931-857X (doi:10.1152/ajprenal.00074.2012)

Davies, S.A., Overend, G., Sebastian, S., Cundall, M., Cabrero, P., Dow, J.A.T., and Terhzaz, S. (2012) Immune and stress response 'cross-talk' in the Drosophila Malpighian tubule. Journal of Insect Physiology, 58 (4). pp. 488-497. ISSN 0022-1910 (doi:10.1016/j.jinsphys.2012.01.008)

Dow, J.A.T. (2012) William R. Harvey: an appreciation. Journal of Insect Physiology, 58 (4). pp. 428-430. ISSN 0022-1910 (doi:10.1016/j.jinsphys.2011.09.019)

Hirata, T., Czapar, A., Brin, L., Haritonova, A., Bondeson, D.P., Linser, P., Cabrero, P., Thompson, J., Dow, J.A.T., and Romero, M.F. (2012) Ion and solute transport by Prestin in Drosophila and Anopheles. Journal of Insect Physiology, 58 (4). pp. 563-9. ISSN 0022-1910 (doi:10.1016/j.jinsphys.2012.01.009)

Overend, G., Cabrero, P., Guo, A.X., Sebastian, S., Cundall, M., Armstrong, H., Mertens, I., Schoofs, L., Dow, J.A.T., and Davies, S.-A. (2012) The receptor guanylate cyclase Gyc76C and a peptide ligand, NPLP1-VQQ, modulate the innate immune IMD pathway in response to salt stress. Peptides, 34 (1). pp. 209-218. ISSN 0196-9781 (doi:10.1016/j.peptides.2011.08.019)

Bratty, M.A., Chintapalli, V.R., Dow, J.A.T., Zhang, T., and Watson, D.G. (2012) Metabolomic profiling reveals that Drosophila melanogaster larvae with the y mutation have altered lysine metabolism. FEBS Open Bio, 2 . pp. 217-221. ISSN 2211-5463 (doi:10.1016/j.fob.2012.07.007)

Chintapalli, V., Terhzaz, S., Wang, J., Al Bratty, M., Watson, D.G., Herzyk, P., Davies, S.A., and Dow, J.A.T. (2012) Functional correlates of positional and gender-specific renal asymmetry in Drosophila. PLoS ONE, 7 (4). e32577. ISSN 1932-6203 (doi:10.1371/journal.pone.0032577)

Terhzaz, S., Cabrero, P., Robben, J.H., Radford, J.C., Hudson, B., Milligan, G., Dow, J.A.T., and Davies, S. (2012) Mechanism and function of Drosophila capa GPCR: a desiccation stress-responsive receptor with functional homology to human neuromedinU receptor. PLoS ONE, 7 (1). e29897. ISSN 1932-6203 (doi:10.1371/journal.pone.0029897)

Terhzaz, S., Cabrero, P., Robben, J.H., Radford, J.C., Hudson, B.D., Milligan, G., Dow, J.A.T., and Davies, S.A. (2012) Mechanism and function of drosophila capa GPCR: a desiccation stress-responsive receptor with functional homology to human neuromedinU receptor. PLoS ONE, 7 (1). e29897. ISSN 1932-6203 (doi:10.1371/journal.pone.0029897)

Al Bratty, M., Hobani, Y., Dow, J.A.T., and Watson, D.G. (2011) Metabolomic profiling of the effects of allopurinol on Drosophila melanogaster. Metabolomics, 7 (4). pp. 542-548. ISSN 1573-3882 (doi:10.1007/s11306-011-0275-6)

Dow, J.A.T. (2011) The versatile stellate cell – More than just a space-filler. Journal of Insect Physiology, 58 (4). pp. 467-472. ISSN 0022-1910 (doi:10.1016/j.jinsphys.2011.12.003)

Terhzaz, S., Finlayson, A.J., Stirrat, L., Yang, J.L., Tricoire, H., Woods, D.J., Dow, J.A.T., and Davies, S.A. (2010) Cell-specific inositol 1,4,5 trisphosphate 3-kinase mediates epithelial cell apoptosis in response to oxidative stress in Drosophila. Cellular Signalling, 22 (5). pp. 737-748. ISSN 0898-6568 (doi:10.1016/j.cellsig.2009.12.009)

Terhzaz, S., Cabrero, P., Chintapalli, V.R., Davies, S.A., and Dow, J.A.T. (2010) Mislocalization of mitochondria and compromised renal function and oxidative stress resistance in Drosophila SesB mutants. Physiological Genomics, 41 (1). pp. 33-41. ISSN 1094-8341 (doi:10.1152/physiolgenomics.00147.2009)

Beyenbach, K.W., Skaer, H., and Dow, J.A.T. (2010) The developmental, molecular, and transport biology of Malpighian tubules. Annual Review of Entomology, 55 . pp. 351-374. ISSN 0066-4170 (doi:10.1146/annurev-ento-112408-085512)

Dow, J.A.T., and Romero, M.F. (2010) Drosophila provides rapid modeling of renal development, function, and disease. AJP: Renal Physiology, 299 (6). F1237-F1244. ISSN 0363-6127 (doi:10.1152/ajprenal.00521.2010)

Terhzaz, S., Cabrero, P., Chintapalli, V.R., Davies, S.A., and Dow, J.A.T. (2010) Mislocalization of mitochondria and compromised renal function and oxidative stress resistance in Drosophila SesB mutants. Physiological Genomics, 41 (1). pp. 33-41. ISSN 1094-8341 (doi:10.1152/physiolgenomics.00147.2009)

Kamleh, M.A., Hobani, Y., Dow, J.A.T., Zheng, L., and Watson, D.G. (2009) Towards a platform for the metabonomic profiling of different strains of Drosophila melanogaster using liquid chromatography-Fourier transform mass spectrometry. FEBS Journal, 276 (22). pp. 6798-6809. ISSN 1742-464X (doi:10.1111/j.1742-4658.2009.07397.x)

Davies, S.A., and Dow, J.A.T. (2009) Modulation of epithelial innate immunity by autocrine production of nitric oxide. General and Comparative Endocrinology, 162 (1). pp. 113-121. ISSN 0016-6480 (doi:10.1016/j.ygcen.2008.09.012)

Simons, M. et al. (2009) Electrochemical cues regulate assembly of the Frizzled/Dishevelled complex at the plasma membrane during planar epithelial polarization. Nature Cell Biology, 11 (3). pp. 286-294. ISSN 1465-7392 (doi:10.1038/ncb1836)

Dow, J.A.T. (2009) Insights into the Malpighian tubule from functional genomics. Journal of Experimental Biology, 212 (3). pp. 435-445. ISSN 0022-0949 (doi:10.1242/jeb.024224)

Dow, J.A.T. (2009) Where it all began (nearly). Journal of Experimental Biology, 212 (3). pp. 327-328. ISSN 0022-0949 (doi:10.1242/jeb.021964)

Kettlewell, S., Cabrero, P., Nicklin, S.A., Dow, J.A.T., Davies, S.A., and Smith, G.L. (2009) Changes of intra-mitochondrial Ca2+ in adult ventricular cardiomyocytes examined using a novel fluorescent Ca2+ indicator targeted to mitochondria. Journal of Molecular and Cellular Cardiology, 46 (6). pp. 891-901. ISSN 0022-2828 (doi:10.1016/j.yjmcc.2009.02.016)

Stergiopoulos, K., Cabrero, P., Davies, S.A., and Dow, J.A.T. (2009) Salty dog, an SLC5 symporter, modulates Drosophila response to salt stress. Physiological Genomics, 37 (1). pp. 1-11. ISSN 1094-8341 (doi:10.1152/physiolgenomics.90360.2008)

Kamleh, M.A., Hobani, Y., Dow, J.A.T., and Watson, D.G. (2008) Metabolomic profiling of Drosophila using liquid chromatography Fourier transform mass spectrometry. FEBS Letters, 582 (19). pp. 2916-2922. ISSN 0014-5793 (doi:10.1016/j.febslet.2008.07.029)

Day, J. P., Wang, S.M., Allan, A.K., Kean, L., Davies, S.A., Gray, J.V., and Dow, J.A.T. (2008) Identification of two partners from the bacterial Kef exchanger family for the apical plasma membrane V-ATPase of Metazoa. Journal of Cell Science, 121 (15). pp. 2612-2619. ISSN 0021-9533 (doi:10.1242/jcs.033084)

Evans, J.M., Day, J.P., Cabrero, P., Dow, J.A.T., and Davies, S.A. (2008) A new role for a classical gene: white transports cyclic GMP. Journal of Experimental Biology, 211 . pp. 890-899. ISSN 0022-0949 (doi:10.1242/jeb.014837)

Baker, D.A., Meadows, L.A., Wang, J., Dow, J.A.T., and Russell, S. (2007) Variable sexually dimorphic gene expression in laboratory strains of Drosophila melanogaster. BMC Genomics, 8 . p. 454. ISSN 1471-2164 (doi:10.1186/1471-2164-8-454)

Chintapalli, V.R., Wang, J., and Dow, J.A.T. (2007) Using FlyAtlas to identify better Drosophila melanogaster models of human disease. Nature Genetics, 39 . pp. 715-720. (doi:10.1038/ng2049)

Dow, JAT (2007) Integrative physiology, functional genomics and the phenotype gap: a guide for comparative physiologists. Journal of Experimental Biology, 210 . pp. 1632-1640. (doi:10.1242/jeb.002691)

Dow, JAT (2007) Model organisms and molecular genetics for endocrinology. General and Comparative Endocrinology, 153 . pp. 3-12. ISSN 0016-6480 (doi:10.1016/j.ygcen.2007.01.023)

Yang, J, McCart, C, Woods, DJ, Terhzaz, S, Greenwood, KG, Ffrench-Constant, RH, and Dow, JAT (2007) A Drosophila systems approach to xenobiotic metabolism. Physiological Genomics, 30 . pp. 223-231. ISSN 1094-8341 (doi:10.1152/physiolgenomics.00018.2007)

Du, J., Kean, L., Allan, A.K., Southall, T.D., Davies, S.A., McInerny, C.J., and Dow, J.A.T. (2006) The SzA mutations of the B subunit of the Drosophila vacuolar H+ ATPase identify conserved residues essential for function in fly and yeast. Journal of Cell Science, 119 (12). pp. 2542-2551. ISSN 0021-9533 (doi:10.1242/jcs.02983)

Dow, JAT, and Davies, SA (2006) The Malpighian tubule: Rapid insights from post-genomic biology. Journal of Insect Physiology, 52 . pp. 365-378. ISSN 0022-1910 (doi:10.1016/j.jinsphys.2005.10.007)

Southall, T.D., Terhzaz, S, Cabrero, P, Chintapalli, V.R., Evans, J.M., Dow, J.A.T, and Davies, S.A. (2006) Novel subcellular locations and functions for secretory pathway Ca2+/Mn2+-ATPases. Physiological Genomics, 26 . pp. 35-45. ISSN 1094-8341 (doi:10.1152/physiolgenomics.00038.2006)

Terhzaz, S, Southall, TD, Lilley, KS, Kean, L, Allan, AK, Davies, SA, and Dow, JAT (2006) Differential gel electrophoresis and transgenic mitochondrial calcium reporters demonstrate spatiotemporal filtering in calcium control of mitochondria. Journal of Biological Chemistry, 281 . pp. 18849-18858. ISSN 0021-9258 (doi:10.1074/jbc.M603002200)

Allan, AK, Du, J, Davies, SA, and Dow, JAT (2005) Genome-wide survey of V-ATPase genes in Drosophila reveals a conserved renal phenotype for lethal alleles. Physiological Genomics, 22 . pp. 128-138. ISSN 1094-8341 (doi:10.1152/physiolgenomics.00233.2004)

Day, JP, Dow, JAT, Houslay, MD, and Davies, SA (2005) Cyclic nucleotide phosphodiesterases in Drosophila melanogaster. Biochemical Journal, 388 . pp. 333-342. ISSN 0264-6021 (doi:10.1042/BJ20050057)

Dow, J (2005) Physiology engages with functional genomics - at last. Genome Biology, 6 (8). pp. 3351-3353. (doi:10.1186/gb-2005-6-8-335)

Evans, JM, Allan, AK, Davies, SA, and Dow, JAT (2005) Sulphonylurea sensitivity and enriched expression implicate inward rectifier K+ channels in Drosophila melanogaster renal function. Journal of Experimental Biology, 208 . pp. 3771-3783.

Gilleard, JS, Woods, DJ, and Dow, JAT (2005) Model-organism genomics in veterinary parasite drug-discovery. Trends in Parasitology, 21 . pp. 302-305. (doi:10.1016/j.pt.2005.05.007)

Johnson, EC, Shafer, OT, Trigg, JS, Park, J, Schooley, DA, Dow, JA, and Taghert, PH (2005) A novel diuretic hormone receptor in Drosophila: evidence for conservation of CGRP signaling. Journal of Experimental Biology, 208 . pp. 1239-1246. (doi:10.1242/jeb.01529)

Kaufmann, N, Mathai, JC, Hill, WG, Dow, JAT, Zeidel, ML, and Brodsky, JL (2005) Developmental expression and biophysical characterization of a Drosophila melanogaster aquaporin. American Journal of Physiology: Cell Physiology, 289 . C397-C407. (doi:10.1152/ajpcell.00612.2004)

MacPherson, MR, Pollock, VP, Kean, L, Southall, TD, Giannakou, ME, Broderick, KE, Dow, JAT, Hardie, RC, and Davies, SA (2005) Transient receptor potential-like channels are essential for calcium signaling and fluid transport in a Drosophila epithelium. Genetics, 169 . pp. 1541-1552. (doi:10.1534/genetics.104.035139)

McGettigan, J et al. (2005) Insect renal tubules constitute a cell-autonomous immune system that protects the organism against bacterial infection. Insect Biochemistry and Molecular Biology, 35 . pp. 741-754. (doi:10.1016/j.ibmb.2005.02.017)

Broderick, KE, Kean, L, Dow, JAT, Pyne, NJ, and Davies, SA (2004) Ectopic expression of bovine type 5 phosphodiesterase confers a renal phenotype in Drosophila. Journal of Biological Chemistry, 279 . pp. 8159-8168. ISSN 0021-9258 (doi:10.1074/jbc.M304679200)

Cabrero, P, Pollock, VP, Davies, SA, and Dow, JAT (2004) A conserved domain of alkaline phosphatase expression in the Malpighian tubules of dipteran insects. Journal of Experimental Biology, 207 . pp. 3299-3305. (doi:10.1242/jeb.01156)

MacPherson, MR, Broderick, KE, Graham, S, Day, JP, Houslay, MD, Dow, JAT, and Davies, SA (2004) The dg2 (for) gene confers a renal phenotype in Drosophila by modulation of cGMP-specific phosphodiesterase. Journal of Experimental Biology, 207 . pp. 2769-2776. (doi:10.1242/jeb.01086)

Pollock, VP, McGettigan, J, Cabrero, P, Maudlin, IM, Dow, JAT, and Davies, SA (2004) Conservation of capa peptide-induced nitric oxide signalling in Diptera. Journal of Experimental Biology, 207 . pp. 4135-4145. (doi:10.1242/jeb.01255)

Radford, JHC, Terhzaz, S, Cabrero, P, Davies, SA, and Dow, JAT (2004) Functional characterisation of the Anopheles leucokinins and their cognate G-protein coupled receptor. Journal of Experimental Biology, 207 . pp. 4573-4586. (doi:10.1242/jeb.01317)

Torrie, LS, Radford, JC, Southall, TD, Kean, L, Dinsmore, AJ, Davies, SA, and Dow, JAT (2004) Resolution of the insect ouabain paradox. Proceedings of the National Academy of Sciences of the United States of America, 101 . pp. 13689-13693. (doi:10.1073/pnas.0403087101)

Wang, J, Kean, L, Yang, JL, Allan, AK, Davies, SA, Herzyk, P, and Dow, JAT (2004) Function-informed transcriptome analysis of Drosophila renal tubule. Genome Biology, 5 .

Broderick, KE, MacPherson, MR, Regulski, M, Tully, T, Dow, JAT, and Davies, SA (2003) Interactions between epithelial nitric oxide signaling and phosphodiesterase activity in Drosophila. American Journal of Physiology: Cell Physiology, 285 . C1207-C1218. (doi:10.1152/ajpcell.00123.2003)

Dow, J (2003) The Drosophila genome: the way forward. Briefings in Functional Genomics and Proteomics, 2 (2). pp. 92-93. (doi:10.1093/bfgp%2F2.2.92)

Dow, J (2003) The Drosophila phenotype gap ù and how to close it. Briefings in Functional Genomics and Proteomics, 2 (2). pp. 121-127. (doi:10.1093/bfgp%2F2.2.121)

Dow, JAT, and Davies, SA (2003) Integrative physiology and functional genomics of epithelial function in a genetic model organism. Physiological Reviews, 83 . pp. 687-729. (doi:10.1152/physrev.00035.2002)

Pollock, VP, Radford, JC, Pyne, S, Hasan, G, Dow, JAT, and Davies, SA (2003) norpA and itpr mutants reveal roles for phospholipase C and inositol (1,4,5)-trisphosphate receptor in Drosophila melanogaster renal function. Journal of Experimental Biology, 206 . pp. 901-911. (doi:10.1242/jeb.00189)

Cabrero, P, Radford, JC, Broderick, KE, Costes, L, Veenstra, JA, Spana, EP, Davies, SA, and Dow, JAT (2002) The Dh gene of Drosophila melanogaster encodes a diuretic peptide that acts through cyclic AMP. Journal of Experimental Biology, 205 . pp. 3799-3807.

Kean, L., Cazenave, W., Costes, L., Broderick, K.E., Graham, S., Pollock, V.P., Davies, S.A., Veenstra, J.A., and Dow, J.A.T. (2002) Two nitridergic peptides are encoded by the gene capability in Drosophila melanogaster. American Journal of Physiology: Regulatory Integrative and Comparative Physiology, 282 . R1297-R1307. (doi:10.1152/ajpregu.00584.2001)

Radford, JC, Davies, SA, and Dow, JAT (2002) Systematic G-protein-coupled receptor analysis in Drosophila melanogaster identifies a leucokinin receptor with novel roles. Journal of Biological Chemistry, 277 . pp. 38810-38817. ISSN 0021-9258 (doi:10.1074/jbc.M203694200)

Dow, JAT, and Davies, SA (2001) The Drosophila melanogaster malpighian tubule. Advances in Insect Physiology, 28 . pp. 1-83.

Giannakou, ME, and Dow, JAT (2001) Characterization of the Drosophila melanogaster alkali-metal/proton exchanger (NHE) gene family. Journal of Experimental Biology, 204 . pp. 3703-3716.

MacPherson, MR, Pollock, VP, Broderick, KE, Kean, L, OConnell, FC, Dow, JAT, and Davies, SA (2001) Model organisms: New insights into ion channel and transporter function. L-type calcium channels regulate epithelial fluid transport in Drosophila melanogaster. American Journal of Physiology: Cell Physiology, 280 . C394-C407.

This list was generated on Wed Jun 19 13:43:19 2013 BST.

Grants and Awards listed are those received whilst working with the University of Glasgow.

  • FlyAtlas2: a definitive, expanded NGS expression resource for the Drosophila community and beyond.
    Biotechnology and Biological Sciences Research Council
    2013 - 2017
     
  • Drosophila model of oxalate nephrolithiasis
    National Institute of Health
    2012 - 2013
     
  • Japan-Systems Approaches to Addressing Food Security: Novel methodology for pest control using key regulators of insect survival against infection
    Biotechnology and Biological Sciences Research Council
    2012 - 2015
     
  • A new direction for insect control: transporters as novel targets for insecticidal compunds.
    Scottish Universities Life Sciences Alliance
    2012 - 2012
     
  • Extraordinary pH - the mechanism of generation of pH 12 in living systems
    Biotechnology and Biological Sciences Research Council
    2012 - 2014
     
  • Unravelling the function of the Nha gene family
    BBSRC
    2010 - 2013
     
  • Epithelial stress sensors: novel roles for cytochrome P450s and organellar calcium in integrated stress and immune responses.
    BBSRC
    2009 - 2013
     
  • Genetic, proteomic and functional analysis of junctional complexes in Drosophila
    BBSRC
    2008 - 2011
     
  • FlyAtlas: a comprehensive online atlas of gene expression in Drosophilia.
    BBSRC
    2008 - 2010
     
  • Cyclic nucleotide signalling in innate immunity
    BBSRC
    2007 - 2010
     
  • Spatiotemporal filtering in calcium control of mitochondrial function
    BBSRC
    2006 - 2009
     
  • Investigation of calcium signalling in sarcoplasmic riticulum of cardiac myocytes using a novel targeted reporter
    BBSRC
    2005 - 2008
     
  • Exploration of cyclic 3', 5' guanosine monophosphate (cGMP) signalling dynamics in vivo
    BBSRC
    2004 - 2008
     
  • Confocal laser scanning microscope
    BBSRC
    2003 - 2006
     
  • Comparative integrative physiology of novel branches of the NA+/H+ exchanger family
    BBSRC
    2003 - 2006
     
  • Function of intracellular calcium pools in renal transport - unravelling complexities using targeted calcium reporters
    BBSRC
    2003 - 2006
     
  • Affymetrix array service for the UK Drosophila Community
    BBSRC
    2002 - 2006
     
  • Functional Genomics in Drosophila
    University of Cambridge
    2001 - 2005
     

Editorial Board

  • 2007 - ongoing: Journal of Experimental Biology - Editor
  • 2006 - ongoing: Physiological Genomics - Associate Editor
  • 2006 - ongoing: Advances in Experimental Biology - Member of Editorial Advisory Board
  • 2002 - ongoing: Briefings in Functional Genomics and Proteomics
  • 1999 - ongoing: Arthropod Structure & Function

Grant Advisory Board

  • 2010 - 2010: BBSRC - Member of REI panel
  • 2009 - 2009: BBSRC - ERA SysBio Plus Grant Panel
  • 2008 - 2011: BBSRC - Data Sharing Policy Management Group
  • 2008 - 2011: BBSRC - Strategy Group; Integrative and Systems Biology
  • 2008 - 2009: BBSRC - BBR Grant Panel
  • 2004 - 2005: BBSRC - Strategic Research Studentship Committee
  • 2004 - 2008: BBSRC - Strategy Group, The Healthy Animal
  • 2004 - 2007: European Science Foundation - Core Group member, Life and Environmental Science Committee
  • 2000 - 2003: BBSRC - Drosophila Steering Group, Chair
  • 2000 - 2004: ESF - Life & Environmental Sciences Plenary Committee
  • 1999 - 2003: BBSRC - Animal Sciences Panel, 1999-2002; JREI Panel, 1999-2002; Functional Genomics Workshop, 1999-2003

Invited International Presentations

  • 2009: Hong Kong - 16th International Congress of Comparative Endocrinology
  • 2008: Cornell University, USA - Robert L. Patton Distinguished Lecture in Entomology
  • 2008: Marseille, France - Society for Experimental Biology
  • 2007: Philadelphia, USA - International Drosophila Conference
  • 2006: San Diego, USA - American Society for Nephrology Annual Meeting
  • 2006: Banff, Canada - Journal of Experimental Biology Discussion Meeting
  • 2006: Manchester UK - Plenary, Conference European Comparative Endocrinology
  • 2005: San Diego, USA - XXXVth International Congress of Physiological Sciences
  • 2005: Barcelona, Spain - Society for Experimental Biology
  • 2004: Uppsala, Sweden - Conference European Comparative Endocrinology
  • 2004: Bidder Lecture, Society for Experimental Biology
  • 2004: International Drosophila conference - Bethesda, USA
  • 2003: University of Potsdam, Germany - Workshop on comparative Physiology
  • 2003: Australia - International Congress of Comparative Biochemistry & Physiology
  • 2003: London, UK - 3rd BBSRC ARK Genomics Workshop
  • 2002: Rowett Institute, Aberdeen - Plenary, SEERAD Genomics Taskforce Workshop
  • 2001: Glasgow, UK - British Association Festival of Science
  • 2001: Aberdeen, UK - Plenary, Royal Entomological Society Insects and disease
  • 2001: Sorrento, Italy - Symposium of the Society for Experimental Biology
  • 2001: Bethesda, USA - NIDDK, National Institutes of Health
  • 2000: Brazil - International Congress of Entomology
  • 2000: Liege, Belgium - International Congress of Comparative Physiology and Biochemistry
  • 1999: Birmingham, UK - Joint meeting: British and European Endocrine Societies

Prizes, Awards and Distinctions

  • 2009: Visiting Research Professor, King Saud University
  • 2004: Bidder Lecture, Society for Experimental Biology

Professional Learned Society

  • 2010 - ongoing: Royal Society of Edinburgh - Fellow
  • 2009 - 2012: Physiological Society - Trustee and Member of Council
  • 2001 - ongoing: Genetical Society - Member
  • 2000 - ongoing: Genetics Society of America - Member
  • 1997 - ongoing: Physiological Society - Member
  • 1985 - ongoing: British Cell Biology Society - Member
  • 1984 - ongoing: Royal Entomological Society - Member; Fellow from 1985
  • 1980 - ongoing: Society for Experimental Biology - Member