Dr Brian Smith

  • Lecturer (Institute of Molecular Cell and Systems Biology)
  • Affiliate (Polyomics Facility)

telephone: 01413305167
email: Brian.Smith@glasgow.ac.uk

B4.20 Level B4
Molecular Cell & Systems Biology
Joseph Black Building
Glasgow G12 8QQ


NMR spectroscopy for the determination of protein and nucleic acid structure, dynamics and interaction. Methylated DNA binding proteins. Nematode fatty acid binding proteins.

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Jump to: 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006 | 2005 | 2004 | 2002 | 2001
Number of items: 39.

2014

Beckham, K. S.H. et al. (2014) The metabolic enzyme AdhE controls the virulence of Escherichia coli O157:H7. Molecular Microbiology, 93 (1). pp. 199-211. ISSN 0950-382X (doi:10.1111/mmi.12651)

Cameron, R. T., Quinn, S. D., Cairns, L. S., MacLeod, R., Samuel, I. D.W., Smith, B. O., Penedo, J. C., and Baillie, G. S. (2014) The phosphorylation of Hsp20 enhances its association with amyloid-β to increase protection against neuronal cell death. Molecular and Cellular Neuroscience, 61 . pp. 46-55. ISSN 1044-7431 (doi:10.1016/j.mcn.2014.05.002)

Ibáñez-Shimabukuro, M., Rey-Burusco, M.F., Cooper, A., Kennedy, M. W., Córsico, B., and Smith, B. O. (2014) Resonance assignment of As-p18, a fatty acid binding protein secreted by developing larvae of the parasitic nematode Ascaris suum. Biomolecular NMR Assignments, 8 (1). pp. 33-36. ISSN 1874-2718 (doi:10.1007/s12104-012-9447-1)

Vance, S. J., McDonald, R. E., Cooper, A., Kennedy, M. W., and Smith, B. O. (2014) Resonance assignments for latherin, a natural surfactant protein from horse sweat. Biomolecular NMR Assignments, 8 (1). pp. 213-216. ISSN 1874-2718 (doi:10.1007/s12104-013-9485-3)

Yvon, C., Surman, A. J., Hutin, M., Alex, J., Smith, B. O., Long, D. L., and Cronin, L. (2014) Polyoxometalate clusters integrated into peptide chains and as inorganic amino acids: solution- and solid-phase approaches. Angewandte Chemie (International Edition), 53 (13). pp. 3336-3341. ISSN 1433-7851 (doi:10.1002/anie.201311135)

Rey-Burusco, M.F., Ibañez-Shimabukuro, M., Cooper, A., Kennedy, M. W., Córsico, B., and Smith, B. O. (2014) 1H, 13C and 15N chemical shift assignments of Na-FAR-1, a helix-rich fatty acid and retinol binding protein of the parasitic nematode Necator americanus. Biomolecular NMR Assignments, 8 (1). pp. 19-21. ISSN 1874-2718 (doi:10.1007/s12104-012-9444-4)

Mccaughey, L. C. et al. (2014) Lectin-like bacteriocins from Pseudomonas spp. utilise D-rhamnose containing lipopolysaccharide as a cellular receptor. PLoS Pathogens, 10 (2). e1003898. ISSN 1553-7366 (doi:10.1371/journal.ppat.1003898)

Josts, I., Grinter, R., Kelly, S. M., Mosbahi, K., Roszak, A., Cogdell, R., Smith, B. O., Byron, O., and Walker, D. (2014) Recombinant expression, purification, crystallization and preliminary X-ray diffraction analysis of the C-terminal DUF490963–1138domain of TamB fromEscherichia coli. Acta Crystallographica. Section F: Structural Biology Communications, 70 (9). pp. 1272-1275. ISSN 1744-3091 (doi:10.1107/S2053230X14017403)

2013

Laird, J. et al. (2013) Identification of the domains of cauliflower mosaic virus protein P6 responsible for suppression of RNA silencing and salicylic acid signalling. Journal of General Virology, 94 (12). pp. 2777-2789. ISSN 0022-1317 (doi:10.1099/vir.0.057729-0)

Laird, J. et al. (2013) Identification of the domains of cauliflower mosaic virus protein P6 responsible for suppression of RNA-silencing and salicylic acid-signalling. Journal of General Virology, 94 (12). pp. 2777-2789. ISSN 0022-1317 (doi:10.1099/vir.0.057729-0)

Hamatsu, J. et al. (2013) High-resolution heteronuclear multidimensional NMR of proteins in living insect cells using a baculovirus protein expression system. Journal of the American Chemical Society, 135 (5). pp. 1688-1691. ISSN 0002-7863 (doi:10.1021/ja310928u)

Kennedy, M.W., Córsico, B., Cooper, A., and Smith, B.O. (2013) The unusual lipid-binding proteins of nematodes: NPAs, nemFABPs and FARs. In: Kennedy, M. and Harnett, m. (eds.) Parasitic Nematodes: Molecular Biology, Biochemistry and Immunology [2nd. ed.]. CABI; Wallingford; UK, pp. 397-412. ISBN 9781845937591

Vance, S.J., McDonald, R.E., Cooper, A., Smith, B.O., and Kennedy, M.W. (2013) The structure of latherin, a surfactant allergen protein from horse sweat and saliva. Journal of The Royal Society Interface, 10 (85). Art. 20130453. ISSN 1742-5689 (doi:10.1098/rsif.2013.0453)

2012

Cloix, C., Kaiserli, E., Heilmann, M., Baxter, K.J., Brown, B.A., O'Hara, A., Smith, B.O., Christie, J.M., and Jenkins, G.I. (2012) C-terminal region of the UV-B photoreceptor UVR8 initiates signaling through interaction with the COP1 protein. Proceedings of the National Academy of Sciences of the United States of America, 109 (40). pp. 16366-16370. ISSN 0027-8424 (doi:10.1073/pnas.1210898109)

Gabrielsen, M., Rey-Burusco, M.F., Griffiths, K., Roe, A.J., Cooper, A., Smith, B.O., Kennedy, M.W., and Corsico, B. (2012) Two crystal forms of a helix-rich fatty acid- and retinol-binding protein, Na-FAR-1, from the parasitic nematodeNecator americanus. Acta Crystallographica. Section F: Structural Biology and Crystallization Communications, 68 (7). pp. 835-838. ISSN 1744-3091 (doi:10.1107/S1744309112023597)

Parnell, E., Smith, B. O., Palmer, T. M., Terrin, A., Zaccolo, M., and Yarwood, S. J. (2012) Regulation of the inflammatory response of vascular endothelial cells by EPAC1. British Journal of Pharmacology, 166 (2). pp. 434-446. ISSN 0007-1188 (doi:10.1111/j.1476-5381.2011.01808.x)

Christie, J.M. et al. (2012) Plant UVR8 photoreceptor senses UV-B by tryptophan-mediated disruption of cross-dimer salt bridges. Science, 335 (6075). pp. 1492-1496. ISSN 0036-8075 (doi:10.1126/science.1218091)

Gabrielsen, M., Riboldi-Tunnicliffe, A., Ibáñez-Shimabukuro, M., Griffiths, K., Roe, A.J., Cooper, A., Smith, B., Córsico, B., and Kennedy, M.W. (2012) Useable diffraction data from a multiple microdomain-containing crystal of Ascaris suum As-p18 fatty-acid-binding protein using a microfocus beamline. Acta Crystallographica. Section F: Structural Biology and Crystallization Communications, 68 . pp. 939-941. ISSN 1744-3091 (doi:10.1107/S1744309112026553)

Gabrielsen, M., Riboldi-Tunnicliffe, A., Ibáñez-Shimabukuro, M., Griffiths, K., Roe, A.J., Cooper, A., Smith, B.O., Córsico, B., and Kennedy, M.W. (2012) Useable diffraction data from a multiple microdomain-containing crystal ofAscaris suumAs-p18 fatty-acid-binding protein using a microfocus beamline. Acta Crystallographica. Section F: Structural Biology and Crystallization Communications, 68 (8). pp. 939-941. ISSN 1744-3091 (doi:10.1107/S1744309112026553)

2011

Wang, D. et al. (2011) Identification of bacterial target proteins for the salicylidene acylhydrazide class of virulence blocking compounds. Journal of Biological Chemistry, 286 (34). pp. 29922-29931. ISSN 0021-9258 (doi:10.1074/jbc.M111.233858)

Meenan, N.A.G., Ball, G., Bromek, K., Uhrín, D., Cooper, A., Kennedy, M.W., and Smith, B.O. (2011) Solution structure of a repeated unit of the ABA-1 nematode polyprotein allergen of ascaris reveals a novel fold and two discrete lipid-binding sites. PLoS Neglected Tropical Diseases, 5 (4). e1040. ISSN 1935-2727 (doi:10.1371/journal.pntd.0001040)

2010

Ikeya, T. et al. (2010) NMR protein structure determination in living E. coli cells using nonlinear sampling. Nature Protocols, 5 (6). pp. 1051-1060. ISSN 1754-2189 (doi:10.1038/nprot.2010.69)

2009

MacKenzie, C.D., Smith, B.O., Meister, A., Blume, A., Zhao, X., Lu, J.R., Kennedy, M.W., and Cooper, A. (2009) Ranaspumin-2: structure and function of a surfactant protein from the foam nests of a tropical frog. Biophysical Journal, 96 (12). pp. 4984-4992. ISSN 0006-3495 (doi:10.1016/j.bpj.2009.03.044)

Sakakibara, D. et al. (2009) Protein structure determination in living cells by in-cell NMR spectroscopy. Nature, 458 (7234). pp. 102-105. ISSN 0028-0836 (doi:10.1038/nature07814)

Borland, G., Smith, B.O., and Yarwood, S.J. (2009) EPAC proteins transduce diverse cellular actions of cAMP. British Journal of Pharmacology, 158 (1). pp. 70-86. ISSN 0007-1188 (doi:10.1111/j.1476-5381.2008.00087.x)

2008

dos Reis, F. C.G., Smith, B. O., Santos, C. C. , Costa, T., F., Scharfstein, J., Coombs, G. H., Mottram, J. C., and Lima, A. P. C.A. (2008) The role of conserved residues of chagasin in the inhibition of cysteine peptidases. FEBS Letters, 582 (4). pp. 485-490. ISSN 0014-5793 (doi:10.1016/j.febslet.2008.01.008)

Caldwell, S. T., Cooke, G., Cooper, A., Nutley, M., Rabani, G., Rotello, V., Smith, B. O., and Woisel, P. (2008) Tuneable pseudorotaxane formation between a biotin-avidin bioconjugate and CBPQT(4+). Chemical Communications (23). pp. 2650-2652. ISSN 1359-7345 (doi:10.1039/b803856b)

Caldwell, S. T., Cooke, G., Hewage, S. G., Mabruk, S., Rabani, G., Rotello, V., Smith, B.O., Subramani, C., and Woisel, P. (2008) Model systems for flavoenzyme activity: intramolecular self-assembly of a flavin derivative via hydrogen bonding and aromatic interactions. Chemical Communications (35). pp. 4126-4128. ISSN 1359-7345 (doi:10.1039/b809762c)

2007

Alexander, A. et al. (2007) Probing the solvent-induced tautomerism of a redox-active ureidopyrimidinone. Chemical Communications . pp. 2246-2248. (doi:10.1039/b703070c)

2006

Smith, B.O., Picken, N.C., Westrop, G.D., Bromek, K., Mottram, J.C., and Coombs, G.H. (2006) The structure of Leishmania mexicana ICP provides evidence for convergent evolution of cysteine peptidase inhibitors. Journal of Biological Chemistry, 281 . pp. 5821-5828. ISSN 0021-9258 (doi:10.1074/jbc.M510868200)

Ball, G., Meenan, N., Bromek, K., Smith, B., Bella, J., and Uhrin, D. (2006) Measurement of one-bond C-13(alpha)-H-1(alpha) residual dipolar coupling constants in proteins by selective manipulation of (CH alpha)-H-alpha spins. Journal of Magnetic Resonance, 180 . pp. 127-136. (doi:10.1016/j.jmr.2006.01.017)

Smith, B.O., Westrop, G.D., Mottram, J.C., and Coombs, G.H. (2006) Chemical shift assignments of Leishmania mexicana ICP, a novel cysteine peptidase inhibitor. Journal of Biomolecular NMR, 36 . p. 7. ISSN 0925-2738 (doi:10.1007/s10858-005-4739-8)

2005

Meenan, N.A.G., Cooper, A., Kennedy, M.W., and Smith, B. (2005) Resonance assignment of ABA-1A, from Ascaris suum nematode polyprotein allergen. Journal of Biomolecular NMR, 32 (2). p. 176. ISSN 0925-2738 (doi:10.1007/s10858-005-6070-9)

2004

Weber, M.A. et al. (2004) Blood pressure dependent and independent effects of antihypertensive treatment on clinical events in the VALUE Trial. Lancet, 363 (9426). pp. 2049-2051. ISSN 0140-6736 (doi:10.1016/S0140-6736(04)16456-8)

Smith, B. (2004) Structural analysis of the complement control protein (CCP) modules of GABAB receptor 1a: only one of the two ccp modules is compactly folded. Journal of Biological Chemistry, 279 (46). pp. 48292-48306. ISSN 0021-9258 (doi:10.1074/jbc.M406540200)

2002

Bramham, J., Hodgkinson, J., Smith, B., Uhrin, D., Barlow, P., and Winder, S. (2002) Solution structure of the calponin CH domain and fitting to the 3D-helical reconstruction of F-actin : calponin. Structure, 10 . pp. 249-258.

Smith, B. (2002) Structure of the C3b binding site of CR1 (CD35), the immune adherence receptor. Cell, 108 (6). pp. 769-780. (doi:10.1016/S0092-8674(02)00672-4)

2001

Smith, B. (2001) DNA recognition by the methyl-CpG binding domain of MeCP2. Journal of Biological Chemistry, 276 (5). pp. 3353-3360. ISSN 0021-9258 (doi:10.1074/jbc.M007224200)

Smith, B. (2001) Solution structure and dynamics of the central CCP module pair of a poxvirus complement control protein. Journal of Molecular Biology, 307 (1). pp. 323-339. (doi:10.1006/jmbi.2000.4477)

This list was generated on Fri Oct 31 19:06:55 2014 GMT.
Number of items: 39.

Article

Beckham, K. S.H. et al. (2014) The metabolic enzyme AdhE controls the virulence of Escherichia coli O157:H7. Molecular Microbiology, 93 (1). pp. 199-211. ISSN 0950-382X (doi:10.1111/mmi.12651)

Cameron, R. T., Quinn, S. D., Cairns, L. S., MacLeod, R., Samuel, I. D.W., Smith, B. O., Penedo, J. C., and Baillie, G. S. (2014) The phosphorylation of Hsp20 enhances its association with amyloid-β to increase protection against neuronal cell death. Molecular and Cellular Neuroscience, 61 . pp. 46-55. ISSN 1044-7431 (doi:10.1016/j.mcn.2014.05.002)

Ibáñez-Shimabukuro, M., Rey-Burusco, M.F., Cooper, A., Kennedy, M. W., Córsico, B., and Smith, B. O. (2014) Resonance assignment of As-p18, a fatty acid binding protein secreted by developing larvae of the parasitic nematode Ascaris suum. Biomolecular NMR Assignments, 8 (1). pp. 33-36. ISSN 1874-2718 (doi:10.1007/s12104-012-9447-1)

Vance, S. J., McDonald, R. E., Cooper, A., Kennedy, M. W., and Smith, B. O. (2014) Resonance assignments for latherin, a natural surfactant protein from horse sweat. Biomolecular NMR Assignments, 8 (1). pp. 213-216. ISSN 1874-2718 (doi:10.1007/s12104-013-9485-3)

Yvon, C., Surman, A. J., Hutin, M., Alex, J., Smith, B. O., Long, D. L., and Cronin, L. (2014) Polyoxometalate clusters integrated into peptide chains and as inorganic amino acids: solution- and solid-phase approaches. Angewandte Chemie (International Edition), 53 (13). pp. 3336-3341. ISSN 1433-7851 (doi:10.1002/anie.201311135)

Rey-Burusco, M.F., Ibañez-Shimabukuro, M., Cooper, A., Kennedy, M. W., Córsico, B., and Smith, B. O. (2014) 1H, 13C and 15N chemical shift assignments of Na-FAR-1, a helix-rich fatty acid and retinol binding protein of the parasitic nematode Necator americanus. Biomolecular NMR Assignments, 8 (1). pp. 19-21. ISSN 1874-2718 (doi:10.1007/s12104-012-9444-4)

Mccaughey, L. C. et al. (2014) Lectin-like bacteriocins from Pseudomonas spp. utilise D-rhamnose containing lipopolysaccharide as a cellular receptor. PLoS Pathogens, 10 (2). e1003898. ISSN 1553-7366 (doi:10.1371/journal.ppat.1003898)

Josts, I., Grinter, R., Kelly, S. M., Mosbahi, K., Roszak, A., Cogdell, R., Smith, B. O., Byron, O., and Walker, D. (2014) Recombinant expression, purification, crystallization and preliminary X-ray diffraction analysis of the C-terminal DUF490963–1138domain of TamB fromEscherichia coli. Acta Crystallographica. Section F: Structural Biology Communications, 70 (9). pp. 1272-1275. ISSN 1744-3091 (doi:10.1107/S2053230X14017403)

Laird, J. et al. (2013) Identification of the domains of cauliflower mosaic virus protein P6 responsible for suppression of RNA silencing and salicylic acid signalling. Journal of General Virology, 94 (12). pp. 2777-2789. ISSN 0022-1317 (doi:10.1099/vir.0.057729-0)

Laird, J. et al. (2013) Identification of the domains of cauliflower mosaic virus protein P6 responsible for suppression of RNA-silencing and salicylic acid-signalling. Journal of General Virology, 94 (12). pp. 2777-2789. ISSN 0022-1317 (doi:10.1099/vir.0.057729-0)

Hamatsu, J. et al. (2013) High-resolution heteronuclear multidimensional NMR of proteins in living insect cells using a baculovirus protein expression system. Journal of the American Chemical Society, 135 (5). pp. 1688-1691. ISSN 0002-7863 (doi:10.1021/ja310928u)

Vance, S.J., McDonald, R.E., Cooper, A., Smith, B.O., and Kennedy, M.W. (2013) The structure of latherin, a surfactant allergen protein from horse sweat and saliva. Journal of The Royal Society Interface, 10 (85). Art. 20130453. ISSN 1742-5689 (doi:10.1098/rsif.2013.0453)

Cloix, C., Kaiserli, E., Heilmann, M., Baxter, K.J., Brown, B.A., O'Hara, A., Smith, B.O., Christie, J.M., and Jenkins, G.I. (2012) C-terminal region of the UV-B photoreceptor UVR8 initiates signaling through interaction with the COP1 protein. Proceedings of the National Academy of Sciences of the United States of America, 109 (40). pp. 16366-16370. ISSN 0027-8424 (doi:10.1073/pnas.1210898109)

Gabrielsen, M., Rey-Burusco, M.F., Griffiths, K., Roe, A.J., Cooper, A., Smith, B.O., Kennedy, M.W., and Corsico, B. (2012) Two crystal forms of a helix-rich fatty acid- and retinol-binding protein, Na-FAR-1, from the parasitic nematodeNecator americanus. Acta Crystallographica. Section F: Structural Biology and Crystallization Communications, 68 (7). pp. 835-838. ISSN 1744-3091 (doi:10.1107/S1744309112023597)

Parnell, E., Smith, B. O., Palmer, T. M., Terrin, A., Zaccolo, M., and Yarwood, S. J. (2012) Regulation of the inflammatory response of vascular endothelial cells by EPAC1. British Journal of Pharmacology, 166 (2). pp. 434-446. ISSN 0007-1188 (doi:10.1111/j.1476-5381.2011.01808.x)

Christie, J.M. et al. (2012) Plant UVR8 photoreceptor senses UV-B by tryptophan-mediated disruption of cross-dimer salt bridges. Science, 335 (6075). pp. 1492-1496. ISSN 0036-8075 (doi:10.1126/science.1218091)

Gabrielsen, M., Riboldi-Tunnicliffe, A., Ibáñez-Shimabukuro, M., Griffiths, K., Roe, A.J., Cooper, A., Smith, B., Córsico, B., and Kennedy, M.W. (2012) Useable diffraction data from a multiple microdomain-containing crystal of Ascaris suum As-p18 fatty-acid-binding protein using a microfocus beamline. Acta Crystallographica. Section F: Structural Biology and Crystallization Communications, 68 . pp. 939-941. ISSN 1744-3091 (doi:10.1107/S1744309112026553)

Gabrielsen, M., Riboldi-Tunnicliffe, A., Ibáñez-Shimabukuro, M., Griffiths, K., Roe, A.J., Cooper, A., Smith, B.O., Córsico, B., and Kennedy, M.W. (2012) Useable diffraction data from a multiple microdomain-containing crystal ofAscaris suumAs-p18 fatty-acid-binding protein using a microfocus beamline. Acta Crystallographica. Section F: Structural Biology and Crystallization Communications, 68 (8). pp. 939-941. ISSN 1744-3091 (doi:10.1107/S1744309112026553)

Wang, D. et al. (2011) Identification of bacterial target proteins for the salicylidene acylhydrazide class of virulence blocking compounds. Journal of Biological Chemistry, 286 (34). pp. 29922-29931. ISSN 0021-9258 (doi:10.1074/jbc.M111.233858)

Meenan, N.A.G., Ball, G., Bromek, K., Uhrín, D., Cooper, A., Kennedy, M.W., and Smith, B.O. (2011) Solution structure of a repeated unit of the ABA-1 nematode polyprotein allergen of ascaris reveals a novel fold and two discrete lipid-binding sites. PLoS Neglected Tropical Diseases, 5 (4). e1040. ISSN 1935-2727 (doi:10.1371/journal.pntd.0001040)

Ikeya, T. et al. (2010) NMR protein structure determination in living E. coli cells using nonlinear sampling. Nature Protocols, 5 (6). pp. 1051-1060. ISSN 1754-2189 (doi:10.1038/nprot.2010.69)

MacKenzie, C.D., Smith, B.O., Meister, A., Blume, A., Zhao, X., Lu, J.R., Kennedy, M.W., and Cooper, A. (2009) Ranaspumin-2: structure and function of a surfactant protein from the foam nests of a tropical frog. Biophysical Journal, 96 (12). pp. 4984-4992. ISSN 0006-3495 (doi:10.1016/j.bpj.2009.03.044)

Sakakibara, D. et al. (2009) Protein structure determination in living cells by in-cell NMR spectroscopy. Nature, 458 (7234). pp. 102-105. ISSN 0028-0836 (doi:10.1038/nature07814)

Borland, G., Smith, B.O., and Yarwood, S.J. (2009) EPAC proteins transduce diverse cellular actions of cAMP. British Journal of Pharmacology, 158 (1). pp. 70-86. ISSN 0007-1188 (doi:10.1111/j.1476-5381.2008.00087.x)

dos Reis, F. C.G., Smith, B. O., Santos, C. C. , Costa, T., F., Scharfstein, J., Coombs, G. H., Mottram, J. C., and Lima, A. P. C.A. (2008) The role of conserved residues of chagasin in the inhibition of cysteine peptidases. FEBS Letters, 582 (4). pp. 485-490. ISSN 0014-5793 (doi:10.1016/j.febslet.2008.01.008)

Caldwell, S. T., Cooke, G., Cooper, A., Nutley, M., Rabani, G., Rotello, V., Smith, B. O., and Woisel, P. (2008) Tuneable pseudorotaxane formation between a biotin-avidin bioconjugate and CBPQT(4+). Chemical Communications (23). pp. 2650-2652. ISSN 1359-7345 (doi:10.1039/b803856b)

Caldwell, S. T., Cooke, G., Hewage, S. G., Mabruk, S., Rabani, G., Rotello, V., Smith, B.O., Subramani, C., and Woisel, P. (2008) Model systems for flavoenzyme activity: intramolecular self-assembly of a flavin derivative via hydrogen bonding and aromatic interactions. Chemical Communications (35). pp. 4126-4128. ISSN 1359-7345 (doi:10.1039/b809762c)

Alexander, A. et al. (2007) Probing the solvent-induced tautomerism of a redox-active ureidopyrimidinone. Chemical Communications . pp. 2246-2248. (doi:10.1039/b703070c)

Smith, B.O., Picken, N.C., Westrop, G.D., Bromek, K., Mottram, J.C., and Coombs, G.H. (2006) The structure of Leishmania mexicana ICP provides evidence for convergent evolution of cysteine peptidase inhibitors. Journal of Biological Chemistry, 281 . pp. 5821-5828. ISSN 0021-9258 (doi:10.1074/jbc.M510868200)

Ball, G., Meenan, N., Bromek, K., Smith, B., Bella, J., and Uhrin, D. (2006) Measurement of one-bond C-13(alpha)-H-1(alpha) residual dipolar coupling constants in proteins by selective manipulation of (CH alpha)-H-alpha spins. Journal of Magnetic Resonance, 180 . pp. 127-136. (doi:10.1016/j.jmr.2006.01.017)

Smith, B.O., Westrop, G.D., Mottram, J.C., and Coombs, G.H. (2006) Chemical shift assignments of Leishmania mexicana ICP, a novel cysteine peptidase inhibitor. Journal of Biomolecular NMR, 36 . p. 7. ISSN 0925-2738 (doi:10.1007/s10858-005-4739-8)

Meenan, N.A.G., Cooper, A., Kennedy, M.W., and Smith, B. (2005) Resonance assignment of ABA-1A, from Ascaris suum nematode polyprotein allergen. Journal of Biomolecular NMR, 32 (2). p. 176. ISSN 0925-2738 (doi:10.1007/s10858-005-6070-9)

Weber, M.A. et al. (2004) Blood pressure dependent and independent effects of antihypertensive treatment on clinical events in the VALUE Trial. Lancet, 363 (9426). pp. 2049-2051. ISSN 0140-6736 (doi:10.1016/S0140-6736(04)16456-8)

Smith, B. (2004) Structural analysis of the complement control protein (CCP) modules of GABAB receptor 1a: only one of the two ccp modules is compactly folded. Journal of Biological Chemistry, 279 (46). pp. 48292-48306. ISSN 0021-9258 (doi:10.1074/jbc.M406540200)

Bramham, J., Hodgkinson, J., Smith, B., Uhrin, D., Barlow, P., and Winder, S. (2002) Solution structure of the calponin CH domain and fitting to the 3D-helical reconstruction of F-actin : calponin. Structure, 10 . pp. 249-258.

Smith, B. (2002) Structure of the C3b binding site of CR1 (CD35), the immune adherence receptor. Cell, 108 (6). pp. 769-780. (doi:10.1016/S0092-8674(02)00672-4)

Smith, B. (2001) DNA recognition by the methyl-CpG binding domain of MeCP2. Journal of Biological Chemistry, 276 (5). pp. 3353-3360. ISSN 0021-9258 (doi:10.1074/jbc.M007224200)

Smith, B. (2001) Solution structure and dynamics of the central CCP module pair of a poxvirus complement control protein. Journal of Molecular Biology, 307 (1). pp. 323-339. (doi:10.1006/jmbi.2000.4477)

Book Section

Kennedy, M.W., Córsico, B., Cooper, A., and Smith, B.O. (2013) The unusual lipid-binding proteins of nematodes: NPAs, nemFABPs and FARs. In: Kennedy, M. and Harnett, m. (eds.) Parasitic Nematodes: Molecular Biology, Biochemistry and Immunology [2nd. ed.]. CABI; Wallingford; UK, pp. 397-412. ISBN 9781845937591

This list was generated on Fri Oct 31 19:06:55 2014 GMT.

Grants and Awards listed are those received whilst working with the University of Glasgow.

  • A novel mechanism of protein uptake in Gram-negative bacteria
    Biotechnology and Biological Sciences Research Council
    2014 - 2017
     
  • Assessing the predictive value of quantitative high-throughput NMR metabolomic analysis for CVD events in a major study of diabetes: ADVANCE
    Chest, Heart & Stroke, Scotland
    2013 - 2015
     
  • How does the plant UV-B photoreceptor UVR8 initiate signalling?
    Biotechnology and Biological Sciences Research Council
    2013 - 2016
     
  • Structure determination and functional analysis through Nuclear Magnetic Resonance
    Boehringer Ingelheim Fonds
    2012 - 2012
     
  • Final structure refinement and functional analysis of Na-FAR-1
    Boehringer Ingelheim Fonds
    2012 - 2012
     
  • The application of a high-throughput NMR metabolomics system to the study of insulin resistance (ISSF Catalyst)
    Wellcome Trust
    2011 - 2014
     
  • Interaction between the essential replication factor TopBP1 and human papillomavirus 16 E1: a novel antiviral target
    Cancer Research UK
    2011 - 2014
     
  • Identification of small molecule activators of EPAC1 to serve as novel anti-inflamatory agents in vascular endothelial cells
    Scottish Universities Life Sciences Alliance
    2011 - 2012
     
  • Quest for the Holy Grail of plant photobiology: a UV-B photoreceptor
    Leverhulme Trust
    2010 - 2014
     
  • Structural and biophysical analysis of novel lipid binding proteins from parasitic helminths
    Wellcome Trust
    2008 - 2012
     
  • The solution structures of newly discovered natural inhibitors of cystine peptidases from eukaryotic and bacterial pathogens
    Wellcome Trust
    2004 - 2008
     
  • Toward Understanding the structural basis of molecular recognition by methylated DNA binding proteins
    Royal Society
    2004 - 2005
     
  • Establishment of high field NMR facility
    Wellcome Trust
    2003 - 2006
     

Grant Advisory Board

  • 2001 - 2009: BBSRC - Member of Executive Committee of CCPN (A Collaborative Computing Project for the NMR Community). Committee Chair 2007-2009

Invited International Presentations

  • 2013: La Plata, Argentina - 8th International Conference on Lipid Binding Proteins: Session chair, Structural Biology of LBPs; Invited speaker, "Structures and ligand binding of all-alpha-helical lipid binding proteins from nematodes"
  • 2009: Ambleside, England - Meeting Chair, 9th CCPN Meeting; speaker, "An overview of fast NMR methods and their practical aspects"
  • 2008: Ambleside, England - Meeting Chair 8th CCPN Meeting
  • 2007: Tokyo, Japan - Invited speaker, Symposium: "Application of advanced analytical techniques to chemical substances", Tokyo Metropolitan University
  • 2007: Ambleside, England - Co-organiser and Session Chair 7th CCPN Meeting - NMR of problematic biological systems
  • 2006: Ambleside, England - Co-organiser and Session Chair 6th CCPN Meeting - Effective and Rapid Structure Determination by NMR
  • 2005: Ambleside, England - Co-organiser and Session Chair 5th CCPN Meeting - NMR and Molecular Interaction

Research Fellowship

  • 1999 - 2003: MRC Career Development Fellowship