Dr Roz Laing

  • Research Associate (Institute of Biodiversity Animal Health and Comparative Medicine)

Research interests

Research interests:

Molecular biology of veterinary parasites; population genetics and genomics of parasitic nematodes; genetic basis of parasite drug resistance; drug metabolism; approaches to the diagnosis and control of anthelmintic resistance

 

Grants

Grants and Awards listed are those received whilst working with the University of Glasgow.

  • Monepantel: anthelmintic resistance and the development of tools for sustainable use
    The Scottish Government
    2017 - 2018
     
  • United States-UK partnering award:Co-infection and resistance (CORE)
    Biotechnology and Biological Sciences Research Council
    2016 - 2020
     
  • Monepantel: anthelmintic resistance and the development of tools for sustainable use
    The Scottish Government
    2016 - 2017
     
  • The BUG consortium Building Upon the Genome: using H. contortus genomic resources to develop novel interventions to control endemic GI parasites
    Biotechnology and Biological Sciences Research Council
    2015 - 2020
     

Publications

List by: Type | Date

Jump to: 2017 | 2016 | 2015 | 2013 | 2012 | 2011 | 2010
Number of items: 10.

2017

Laing, R., Gillan, V. and Devaney, E. (2017) Ivermectin - old drug, new tricks? Trends in Parasitology, (doi:10.1016/j.pt.2017.02.004) (PMID:28285851) (Early Online Publication)

2016

Laing, R., Maitland, K., Lecova, L., Skuce, P. J., Tait, A. and Devaney, E. (2016) Analysis of putative resistance gene loci in UK field populations of Haemonchus contortus after six years of macrocyclic lactone use. International Journal for Parasitology, 46(10), pp. 621-630. (doi:10.1016/j.ijpara.2016.03.010) (PMID:27179994) (PMCID:PMC5011429)

Rezansoff, A. M., Laing, R. and Gilleard, J. S. (2016) Evidence from two independent backcross experiments supports genetic linkage of microsatellite Hcms8a20, but not other candidate loci, to a major ivermectin resistance locus in Haemonchus contortus. International Journal for Parasitology, 46(10), pp. 653-661. (doi:10.1016/j.ijpara.2016.04.007) (PMID:27216082)

2015

Laing, R., Bartley, D. J., Morrison, A. A., Rezansoff, A., Martinelli, A., Laing, S. T. and Gilleard, J. S. (2015) The cytochrome P450 family in the parasitic nematode Haemonchus contortus. International Journal for Parasitology, 45(4), pp. 243-251. (doi:10.1016/j.ijpara.2014.12.001) (PMID:25558056) (PMCID:PMC4365919)

Lecova, L., Růžičková, M., Laing, R., Vogel, H., Szotáková, B., Prchal, L., Lamka, J., Vokřál, I., Skálová, L. and Matoušková, P. (2015) Reliable reference gene selection for quantitative real time PCR in Haemonchus contortus. Molecular and Biochemical Parasitology, 201(2), pp. 123-127. (doi:10.1016/j.molbiopara.2015.08.001) (PMID:26255779)

2013

Laing, R. et al. (2013) The genome and transcriptome of haemonchus contortus, a key model parasite for drug and vaccine discovery. Genome Biology, 14(8), R88. (doi:10.1186/gb-2013-14-8-r88)

Saunders, G. I., Wasmuth, J. D., Beech, R., Laing, R., Hunt, M., Naghra, H., Cotton, J. A., Berriman, M., Britton, C. and Gilleard, J. S. (2013) Characterization and comparative analysis of the complete Haemonchus contortus β-tubulin gene family and implications for benzimidazole resistance in strongylid nematodes. International Journal for Parasitology, 43(6), pp. 465-475. (doi:10.1016/j.ijpara.2012.12.011)

2012

Laing, S.T., Ivens, A., Butler, V., Ravikumar, S.P., Laing, R., Woods, D.J. and Gilleard, J.S. (2012) The transcriptional response of Caenorhabditis elegans to ivermectin exposure identifies novel genes involved in the response to reduced food intake. PLoS ONE, 7(2), e31367. (doi:10.1371/journal.pone.0031367)

2011

Laing, R. et al. (2011) Annotation of two large contiguous regions from the Haemonchus contortus genome using RNA-seq and comparative analysis with Caenorhabditis elegans. PLoS ONE, 6(8), e23216. (doi:10.1371/journal.pone.0023216)

2010

Laing, S., Ivens, A., Laing, R., Ravikumar, S., Butler, V., Woods, D.J. and Gilleard, J.S. (2010) Characterization of the xenobiotic response of Caenorhabditis elegans to the anthelmintic drug albendazole and the identification of novel drug glucoside metabolites. Biochemical Journal, 432(3), pp. 505-514. (doi:10.1042/BJ20101346)

This list was generated on Wed Jun 28 10:18:00 2017 BST.
Jump to: Articles
Number of items: 10.

Articles

Laing, R., Gillan, V. and Devaney, E. (2017) Ivermectin - old drug, new tricks? Trends in Parasitology, (doi:10.1016/j.pt.2017.02.004) (PMID:28285851) (Early Online Publication)

Laing, R., Maitland, K., Lecova, L., Skuce, P. J., Tait, A. and Devaney, E. (2016) Analysis of putative resistance gene loci in UK field populations of Haemonchus contortus after six years of macrocyclic lactone use. International Journal for Parasitology, 46(10), pp. 621-630. (doi:10.1016/j.ijpara.2016.03.010) (PMID:27179994) (PMCID:PMC5011429)

Rezansoff, A. M., Laing, R. and Gilleard, J. S. (2016) Evidence from two independent backcross experiments supports genetic linkage of microsatellite Hcms8a20, but not other candidate loci, to a major ivermectin resistance locus in Haemonchus contortus. International Journal for Parasitology, 46(10), pp. 653-661. (doi:10.1016/j.ijpara.2016.04.007) (PMID:27216082)

Laing, R., Bartley, D. J., Morrison, A. A., Rezansoff, A., Martinelli, A., Laing, S. T. and Gilleard, J. S. (2015) The cytochrome P450 family in the parasitic nematode Haemonchus contortus. International Journal for Parasitology, 45(4), pp. 243-251. (doi:10.1016/j.ijpara.2014.12.001) (PMID:25558056) (PMCID:PMC4365919)

Lecova, L., Růžičková, M., Laing, R., Vogel, H., Szotáková, B., Prchal, L., Lamka, J., Vokřál, I., Skálová, L. and Matoušková, P. (2015) Reliable reference gene selection for quantitative real time PCR in Haemonchus contortus. Molecular and Biochemical Parasitology, 201(2), pp. 123-127. (doi:10.1016/j.molbiopara.2015.08.001) (PMID:26255779)

Laing, R. et al. (2013) The genome and transcriptome of haemonchus contortus, a key model parasite for drug and vaccine discovery. Genome Biology, 14(8), R88. (doi:10.1186/gb-2013-14-8-r88)

Saunders, G. I., Wasmuth, J. D., Beech, R., Laing, R., Hunt, M., Naghra, H., Cotton, J. A., Berriman, M., Britton, C. and Gilleard, J. S. (2013) Characterization and comparative analysis of the complete Haemonchus contortus β-tubulin gene family and implications for benzimidazole resistance in strongylid nematodes. International Journal for Parasitology, 43(6), pp. 465-475. (doi:10.1016/j.ijpara.2012.12.011)

Laing, S.T., Ivens, A., Butler, V., Ravikumar, S.P., Laing, R., Woods, D.J. and Gilleard, J.S. (2012) The transcriptional response of Caenorhabditis elegans to ivermectin exposure identifies novel genes involved in the response to reduced food intake. PLoS ONE, 7(2), e31367. (doi:10.1371/journal.pone.0031367)

Laing, R. et al. (2011) Annotation of two large contiguous regions from the Haemonchus contortus genome using RNA-seq and comparative analysis with Caenorhabditis elegans. PLoS ONE, 6(8), e23216. (doi:10.1371/journal.pone.0023216)

Laing, S., Ivens, A., Laing, R., Ravikumar, S., Butler, V., Woods, D.J. and Gilleard, J.S. (2010) Characterization of the xenobiotic response of Caenorhabditis elegans to the anthelmintic drug albendazole and the identification of novel drug glucoside metabolites. Biochemical Journal, 432(3), pp. 505-514. (doi:10.1042/BJ20101346)

This list was generated on Wed Jun 28 10:18:00 2017 BST.