Mrs Elaine Friel
- Technician (Cardiovascular & Metabolic Health Professional Services)
telephone:
01413304962
email:
Elaine.Friel@glasgow.ac.uk
RC405 Level C4, Institute of C&MS, Bhf Gcrc, Glasgow G12 8TA
Publications
2021
Docherty, C., Bresciani, J., Carswell, A., Chanderseka, A., Friel, E., Stasi, M. and Mercer, J. (2021) An inducible and vascular smooth muscle cell specific Pink-1 knockout induces mitochondrial dysfunction during atherogenesis. International Journal of Molecular Sciences, 22(18), 9993. (doi: 10.3390/ijms22189993) (PMID:34576157) (PMCID:PMC8467198)
2018
Docherty, C. K., Carswell, A., Friel, E. and Mercer, J. R. (2018) Impaired mitochondrial respiration in human carotid plaque atherosclerosis: a potential role for Pink1 in vascular smooth muscle cell energetics. Atherosclerosis, 268, pp. 1-11. (doi: 10.1016/j.atherosclerosis.2017.11.009) (PMID:29156421) (PMCID:PMC6565844)
2016
Diver, L. A. et al. (2016) Common polymorphisms at the CYP17A1 locus associate with steroid phenotype: support for blood pressure genome-wide association study signals at this locus. Hypertension, 67(4), pp. 724-732. (doi: 10.1161/HYPERTENSIONAHA.115.06925) (PMID:26902494) (PMCID:PMC4789491)
2009
Holloway, C.D. et al. (2009) Effects of genetic variation in the aldosterone synthase (CYP11B2) gene on enzyme function. Clinical Endocrinology, 70(3), pp. 363-371. (doi: 10.1111/j.1365-2265.2008.03383.x)
2007
Freel, E.M. et al. (2007) Phenotypic consequences of variation across the aldosterone synthase and 11-beta hydroxylase locus in a hypertensive cohort: data from the MRC BRIGHT Study. Clinical Endocrinology, 67(6), pp. 832-838. (doi: 10.1111/j.1365-2265.2007.02971.x)
2004
Freel, E., Shakerdi, L.A., Friel, E., Wallace, A.M., Davies, E., Fraser, R. and Connell, J.M.C. (2004) Studies on the origin of circulating 18-hydroxycortisol and 18-oxocortisol in normal human subjects. Journal of Clinical Endocrinology and Metabolism, 89(9), pp. 4628-4633. (doi: 10.1210/jc.2004-0379)
Freel, E.M., Shakerdi, L., Friel, E., Wallace, A.M., Davies, E. , Fraser, R. and Connell, J.M.C. (2004) The origin of circulating 18-oxo and 18-hydroxycortisol in normal human subjects. Journal of Clinical Endocrinology and Metabolism, 89(9), pp. 4628-4633. (doi: 10.1210/jc.2004-0379)
Connell, J. M.C., Fraser, R., MacKenzie, S. M. , Friel, E. C., Ingram, M. C., Holloway, C. D. and Davies, E. (2004) The impact of polymorphisms in the gene encoding aldosterone synthase (CYP11B2) on steroid synthesis and blood pressure regulation. Molecular and Cellular Endocrinology, 217(1-2), pp. 243-247. (doi: 10.1016/j.mce.2003.10.025) (PMID:15134824)
Articles
Docherty, C., Bresciani, J., Carswell, A., Chanderseka, A., Friel, E., Stasi, M. and Mercer, J. (2021) An inducible and vascular smooth muscle cell specific Pink-1 knockout induces mitochondrial dysfunction during atherogenesis. International Journal of Molecular Sciences, 22(18), 9993. (doi: 10.3390/ijms22189993) (PMID:34576157) (PMCID:PMC8467198)
Docherty, C. K., Carswell, A., Friel, E. and Mercer, J. R. (2018) Impaired mitochondrial respiration in human carotid plaque atherosclerosis: a potential role for Pink1 in vascular smooth muscle cell energetics. Atherosclerosis, 268, pp. 1-11. (doi: 10.1016/j.atherosclerosis.2017.11.009) (PMID:29156421) (PMCID:PMC6565844)
Diver, L. A. et al. (2016) Common polymorphisms at the CYP17A1 locus associate with steroid phenotype: support for blood pressure genome-wide association study signals at this locus. Hypertension, 67(4), pp. 724-732. (doi: 10.1161/HYPERTENSIONAHA.115.06925) (PMID:26902494) (PMCID:PMC4789491)
Holloway, C.D. et al. (2009) Effects of genetic variation in the aldosterone synthase (CYP11B2) gene on enzyme function. Clinical Endocrinology, 70(3), pp. 363-371. (doi: 10.1111/j.1365-2265.2008.03383.x)
Freel, E.M. et al. (2007) Phenotypic consequences of variation across the aldosterone synthase and 11-beta hydroxylase locus in a hypertensive cohort: data from the MRC BRIGHT Study. Clinical Endocrinology, 67(6), pp. 832-838. (doi: 10.1111/j.1365-2265.2007.02971.x)
Freel, E., Shakerdi, L.A., Friel, E., Wallace, A.M., Davies, E., Fraser, R. and Connell, J.M.C. (2004) Studies on the origin of circulating 18-hydroxycortisol and 18-oxocortisol in normal human subjects. Journal of Clinical Endocrinology and Metabolism, 89(9), pp. 4628-4633. (doi: 10.1210/jc.2004-0379)
Freel, E.M., Shakerdi, L., Friel, E., Wallace, A.M., Davies, E. , Fraser, R. and Connell, J.M.C. (2004) The origin of circulating 18-oxo and 18-hydroxycortisol in normal human subjects. Journal of Clinical Endocrinology and Metabolism, 89(9), pp. 4628-4633. (doi: 10.1210/jc.2004-0379)
Connell, J. M.C., Fraser, R., MacKenzie, S. M. , Friel, E. C., Ingram, M. C., Holloway, C. D. and Davies, E. (2004) The impact of polymorphisms in the gene encoding aldosterone synthase (CYP11B2) on steroid synthesis and blood pressure regulation. Molecular and Cellular Endocrinology, 217(1-2), pp. 243-247. (doi: 10.1016/j.mce.2003.10.025) (PMID:15134824)