Mr David Strachan
- Senior Scientific Officer (School of Cancer Sciences)
email:
David.Strachan@glasgow.ac.uk
R432 Level 4, Institute of Cancer Sciences, Beatson Institute, G61 1bd
Publications
2023
Román-Fernández, A. et al. (2023) Spatial regulation of the glycocalyx component podocalyxin is a switch for prometastatic function. Science Advances, 9(5), eabq1858. (doi: 10.1126/sciadv.abq1858) (PMID:36735782) (PMCID:PMC9897673)
2022
Freckmann, E. C. et al. (2022) Traject3d allows label-free identification of distinct co-occurring phenotypes within 3D culture by live imaging. Nature Communications, 13, 5317. (doi: 10.1038/s41467-022-32958-x) (PMID:36085324) (PMCID:PMC9463449)
2021
Galbraith, L. C.A., Mui, E., Nixon, C., Hedley, A., Strachan, D., MacKay, G., Sumpton, D., Sansom, O. J. , Leung, H. Y. and Ahmad, I. (2021) PPAR-gamma induced AKT3 expression increases levels of mitochondrial biogenesis driving prostate cancer. Oncogene, 40(13), pp. 2355-2366. (doi: 10.1038/s41388-021-01707-7) (PMID:33654198) (PMCID:PMC8016665)
2020
Michalopoulou, E., Auciello, F. R., Bulusu, V., Strachan, D., Campbell, A. D., Tait-Mulder, J., Karim, S. A., Morton, J. P. , Sansom, O. J. and Kamphorst, J. J. (2020) Macropinocytosis renders a subset of pancreatic tumor cells resistant to mTOR inhibition. Cell Reports, 30(8), 2729-2742.e4. (doi: 10.1016/j.celrep.2020.01.080) (PMID:32101748) (PMCID:PMC7043007)
2016
van Loon, J. et al. (2016) Genome-wide association studies identify genetic loci for low von Willebrand factor levels. European Journal of Human Genetics, 24(7), pp. 1035-1040. (doi: 10.1038/ejhg.2015.222) (PMID:26486471)
2015
Mrschtik, M., O'Prey, J., Lao, L.Y., Long, J.S., Beaumatin, F., Strachan, D., O'Prey, M., Skommer, J. and Ryan, K.M. (2015) DRAM-3 modulates autophagy and promotes cell survival in the absence of glucose. Cell Death and Differentiation, 22(10), pp. 1714-1726. (doi: 10.1038/cdd.2015.26) (PMID:25929859) (PMCID:PMC4563785)
2014
Ioannidou, K., Anderson, K. I., Strachan, D., Edgar, J. M. and Barnett, S. C. (2014) Astroglial-axonal interactions during early stages of myelination in mixed cultures using in vitro and ex vivo imaging techniques. BMC Neuroscience, 15(1), p. 59. (doi: 10.1186/1471-2202-15-59)
2012
Dozynkiewicz, M.A. et al. (2012) Rab25 and CLIC3 collaborate to promote integrin recycling from late endosomes/lysosomes and drive cancer progression. Developmental Cell, 22(1), pp. 131-145. (doi: 10.1016/j.devcel.2011.11.008)
Ioannidou, K., Anderson, K.I., Strachan, D., Edgar, J.M. and Barnett, S.C. (2012) Time-lapse imaging of the dynamics of CNS glial-axonal interactions in vitro and ex vivo. PLoS ONE, 7(1), e30775. (doi: 10.1371/journal.pone.0030775)
2010
Padmanabhan, S. et al. (2010) Genome-wide association study of blood pressure extremes identifies variant near UMOD associated with hypertension. PLoS Genetics, 6(10), e1001177. (doi: 10.1371/journal.pgen.1001177)
Articles
Román-Fernández, A. et al. (2023) Spatial regulation of the glycocalyx component podocalyxin is a switch for prometastatic function. Science Advances, 9(5), eabq1858. (doi: 10.1126/sciadv.abq1858) (PMID:36735782) (PMCID:PMC9897673)
Freckmann, E. C. et al. (2022) Traject3d allows label-free identification of distinct co-occurring phenotypes within 3D culture by live imaging. Nature Communications, 13, 5317. (doi: 10.1038/s41467-022-32958-x) (PMID:36085324) (PMCID:PMC9463449)
Galbraith, L. C.A., Mui, E., Nixon, C., Hedley, A., Strachan, D., MacKay, G., Sumpton, D., Sansom, O. J. , Leung, H. Y. and Ahmad, I. (2021) PPAR-gamma induced AKT3 expression increases levels of mitochondrial biogenesis driving prostate cancer. Oncogene, 40(13), pp. 2355-2366. (doi: 10.1038/s41388-021-01707-7) (PMID:33654198) (PMCID:PMC8016665)
Michalopoulou, E., Auciello, F. R., Bulusu, V., Strachan, D., Campbell, A. D., Tait-Mulder, J., Karim, S. A., Morton, J. P. , Sansom, O. J. and Kamphorst, J. J. (2020) Macropinocytosis renders a subset of pancreatic tumor cells resistant to mTOR inhibition. Cell Reports, 30(8), 2729-2742.e4. (doi: 10.1016/j.celrep.2020.01.080) (PMID:32101748) (PMCID:PMC7043007)
van Loon, J. et al. (2016) Genome-wide association studies identify genetic loci for low von Willebrand factor levels. European Journal of Human Genetics, 24(7), pp. 1035-1040. (doi: 10.1038/ejhg.2015.222) (PMID:26486471)
Mrschtik, M., O'Prey, J., Lao, L.Y., Long, J.S., Beaumatin, F., Strachan, D., O'Prey, M., Skommer, J. and Ryan, K.M. (2015) DRAM-3 modulates autophagy and promotes cell survival in the absence of glucose. Cell Death and Differentiation, 22(10), pp. 1714-1726. (doi: 10.1038/cdd.2015.26) (PMID:25929859) (PMCID:PMC4563785)
Ioannidou, K., Anderson, K. I., Strachan, D., Edgar, J. M. and Barnett, S. C. (2014) Astroglial-axonal interactions during early stages of myelination in mixed cultures using in vitro and ex vivo imaging techniques. BMC Neuroscience, 15(1), p. 59. (doi: 10.1186/1471-2202-15-59)
Dozynkiewicz, M.A. et al. (2012) Rab25 and CLIC3 collaborate to promote integrin recycling from late endosomes/lysosomes and drive cancer progression. Developmental Cell, 22(1), pp. 131-145. (doi: 10.1016/j.devcel.2011.11.008)
Ioannidou, K., Anderson, K.I., Strachan, D., Edgar, J.M. and Barnett, S.C. (2012) Time-lapse imaging of the dynamics of CNS glial-axonal interactions in vitro and ex vivo. PLoS ONE, 7(1), e30775. (doi: 10.1371/journal.pone.0030775)
Padmanabhan, S. et al. (2010) Genome-wide association study of blood pressure extremes identifies variant near UMOD associated with hypertension. PLoS Genetics, 6(10), e1001177. (doi: 10.1371/journal.pgen.1001177)