Dr Gavin Blackburn
- Bioinformatician (MVLS Research Facilities)
email:
Gavin.Blackburn@glasgow.ac.uk
Glasgow Polyomics, Wolfson Wohl Cancer Research Centre, Garscube Campus, Bearsden, G61 1QH
Publications
2023
Ross, E. A. et al. (2023) Nanotopography reveals metabolites that maintain the immunomodulatory phenotype of mesenchymal stromal cells. Nature Communications, 14, 753. (doi: 10.1038/s41467-023-36293-7) (PMID:36765065) (PMCID:PMC9918539)
2022
Raposo de Magalhães, C., Farinha, A. P., Blackburn, G., Whitfield, P. D. , Carrilho, R., Schrama, D., Cerqueira, M. and Rodrigues, P. M. (2022) Gilthead seabream liver integrative proteomics and metabolomics analysis reveals regulation by different prosurvival pathways in the metabolic adaptation to stress. International Journal of Molecular Sciences, 23(23), 15395. (doi: 10.3390/ijms232315395) (PMID:36499720) (PMCID:PMC9741202)
O'Brien, Á. C. et al. (2022) Using organic contaminants to constrain the terrestrial journey of the martian meteorite Lafayette. Astrobiology, 22(11), pp. 1351-1362. (doi: 10.1089/ast.2021.0180) (PMID:36264546) (PMCID:PMC9618387)
Dominoni, D. M. et al. (2022) Integrated molecular and behavioural data reveal deep circadian disruption in response to artificial light at night in male Great tits (Parus major). Scientific Reports, 12, 1553. (doi: 10.1038/s41598-022-05059-4) (PMID:35091579) (PMCID:PMC8799718)
2021
Rossitto, G. et al. (2021) High sodium intake, glomerular hyperfiltration and protein catabolism in patients with essential hypertension. Cardiovascular Research, 117(5), pp. 1372-1381. (doi: 10.1093/cvr/cvaa205) (PMID:33053160) (PMCID:PMC8064429)
Biddau, M. et al. (2021) Plasmodium falciparum LipB mutants display altered redox and carbon metabolism in asexual stages and cannot complete sporogony in Anopheles mosquitoes. International Journal for Parasitology, 51(6), pp. 441-453. (doi: 10.1016/j.ijpara.2020.10.011) (PMID:33713652) (PMCID:PMC8126644)
2020
Blackburn, G. et al. (2020) Running on empty: a metabolomics approach to investigating changing energy metabolism during fasted exercise and rest. Metabolites, 10(10), 399. (doi: 10.3390/metabo10100399) (PMID:33050077) (PMCID:PMC7600507)
Daly, R. et al. (2020) Changes in plasma itaconate elevation in early rheumatoid arthritis patients elucidates disease activity associated macrophage activation. Metabolites, 10(6), 241. (doi: 10.3390/metabo10060241) (PMID:32531990) (PMCID:PMC7344783)
2018
Alghamdi, A., Gerasimidis, K. , Blackburn, G., Akinci, D., Edwards, C. , Russell, R. K. and Watson, D. G. (2018) Untargeted metabolomics of extracts from faecal samples demonstrates distinct differences between paediatric Crohn’s disease patients and healthy controls but no significant changes resulting from exclusive enteral nutrition treatment. Metabolites, 8(4), 82. (doi: 10.3390/metabo8040082) (PMID:30467282)
2017
Westrop, G. D., Wang, L., Blackburn, G. J., Zhang, T., Zheng, L., Watson, D. G. and Coombs, G. H. (2017) Metabolomic profiling and stable isotope labelling of Trichomonas vaginalis and Tritrichomonas foetus reveal major differences in amino acid metabolism including the production of 2-hydroxyisocaproic acid, cystathionine and S-methylcysteine. PLoS ONE, 12(12), e0189072. (doi: 10.1371/journal.pone.0189072) (PMID:29267346) (PMCID:PMC5739422)
Alwashih, M. A., Watson, D. G., Andrew, R., Stimson, R. H., Alossaimi, M., Blackburn, G. and Walker, B. R. (2017) Plasma metabolomic profile varies with glucocorticoid dose in patients with congenital adrenal hyperplasia. Scientific Reports, 7, 17092. (doi: 10.1038/s41598-017-17220-5) (PMID:29213133) (PMCID:PMC5719028)
Tsimbouri, P. M. et al. (2017) Stimulation of 3D osteogenesis by mesenchymal stem cells using a nanovibrational bioreactor. Nature Biomedical Engineering, 1, pp. 758-770. (doi: 10.1038/s41551-017-0127-4) (PMID:31015671)
2016
Shaw, C.D. et al. (2016) In vitro selection of miltefosine resistance in promastigotes of Leishmania donovani from Nepal: genomic and metabolomic characterization. Molecular Microbiology, 99(6), pp. 1134-1148. (doi: 10.1111/mmi.13291) (PMID:26713880) (PMCID:PMC4832254)
2015
Daskalaki, E., Blackburn, G., Kalna, G., Zhang, T., Anthony, N. and Watson, D. (2015) A study of the effects of exercise on the urinary metabolome using normalisation to individual metabolic output. Metabolites, 5(1), pp. 119-139. (doi: 10.3390/metabo5010119) (PMID:25734341) (PMCID:PMC4381293)
Articles
Ross, E. A. et al. (2023) Nanotopography reveals metabolites that maintain the immunomodulatory phenotype of mesenchymal stromal cells. Nature Communications, 14, 753. (doi: 10.1038/s41467-023-36293-7) (PMID:36765065) (PMCID:PMC9918539)
Raposo de Magalhães, C., Farinha, A. P., Blackburn, G., Whitfield, P. D. , Carrilho, R., Schrama, D., Cerqueira, M. and Rodrigues, P. M. (2022) Gilthead seabream liver integrative proteomics and metabolomics analysis reveals regulation by different prosurvival pathways in the metabolic adaptation to stress. International Journal of Molecular Sciences, 23(23), 15395. (doi: 10.3390/ijms232315395) (PMID:36499720) (PMCID:PMC9741202)
O'Brien, Á. C. et al. (2022) Using organic contaminants to constrain the terrestrial journey of the martian meteorite Lafayette. Astrobiology, 22(11), pp. 1351-1362. (doi: 10.1089/ast.2021.0180) (PMID:36264546) (PMCID:PMC9618387)
Dominoni, D. M. et al. (2022) Integrated molecular and behavioural data reveal deep circadian disruption in response to artificial light at night in male Great tits (Parus major). Scientific Reports, 12, 1553. (doi: 10.1038/s41598-022-05059-4) (PMID:35091579) (PMCID:PMC8799718)
Rossitto, G. et al. (2021) High sodium intake, glomerular hyperfiltration and protein catabolism in patients with essential hypertension. Cardiovascular Research, 117(5), pp. 1372-1381. (doi: 10.1093/cvr/cvaa205) (PMID:33053160) (PMCID:PMC8064429)
Biddau, M. et al. (2021) Plasmodium falciparum LipB mutants display altered redox and carbon metabolism in asexual stages and cannot complete sporogony in Anopheles mosquitoes. International Journal for Parasitology, 51(6), pp. 441-453. (doi: 10.1016/j.ijpara.2020.10.011) (PMID:33713652) (PMCID:PMC8126644)
Blackburn, G. et al. (2020) Running on empty: a metabolomics approach to investigating changing energy metabolism during fasted exercise and rest. Metabolites, 10(10), 399. (doi: 10.3390/metabo10100399) (PMID:33050077) (PMCID:PMC7600507)
Daly, R. et al. (2020) Changes in plasma itaconate elevation in early rheumatoid arthritis patients elucidates disease activity associated macrophage activation. Metabolites, 10(6), 241. (doi: 10.3390/metabo10060241) (PMID:32531990) (PMCID:PMC7344783)
Alghamdi, A., Gerasimidis, K. , Blackburn, G., Akinci, D., Edwards, C. , Russell, R. K. and Watson, D. G. (2018) Untargeted metabolomics of extracts from faecal samples demonstrates distinct differences between paediatric Crohn’s disease patients and healthy controls but no significant changes resulting from exclusive enteral nutrition treatment. Metabolites, 8(4), 82. (doi: 10.3390/metabo8040082) (PMID:30467282)
Westrop, G. D., Wang, L., Blackburn, G. J., Zhang, T., Zheng, L., Watson, D. G. and Coombs, G. H. (2017) Metabolomic profiling and stable isotope labelling of Trichomonas vaginalis and Tritrichomonas foetus reveal major differences in amino acid metabolism including the production of 2-hydroxyisocaproic acid, cystathionine and S-methylcysteine. PLoS ONE, 12(12), e0189072. (doi: 10.1371/journal.pone.0189072) (PMID:29267346) (PMCID:PMC5739422)
Alwashih, M. A., Watson, D. G., Andrew, R., Stimson, R. H., Alossaimi, M., Blackburn, G. and Walker, B. R. (2017) Plasma metabolomic profile varies with glucocorticoid dose in patients with congenital adrenal hyperplasia. Scientific Reports, 7, 17092. (doi: 10.1038/s41598-017-17220-5) (PMID:29213133) (PMCID:PMC5719028)
Tsimbouri, P. M. et al. (2017) Stimulation of 3D osteogenesis by mesenchymal stem cells using a nanovibrational bioreactor. Nature Biomedical Engineering, 1, pp. 758-770. (doi: 10.1038/s41551-017-0127-4) (PMID:31015671)
Shaw, C.D. et al. (2016) In vitro selection of miltefosine resistance in promastigotes of Leishmania donovani from Nepal: genomic and metabolomic characterization. Molecular Microbiology, 99(6), pp. 1134-1148. (doi: 10.1111/mmi.13291) (PMID:26713880) (PMCID:PMC4832254)
Daskalaki, E., Blackburn, G., Kalna, G., Zhang, T., Anthony, N. and Watson, D. (2015) A study of the effects of exercise on the urinary metabolome using normalisation to individual metabolic output. Metabolites, 5(1), pp. 119-139. (doi: 10.3390/metabo5010119) (PMID:25734341) (PMCID:PMC4381293)
Research datasets
2017
Tsimbouri, P. , Childs, P., Pemberton, G. D., Yang, J., Jayawarna, V., Orapiriyakul, W., Burgess, K., Gonzalez-Garcia, C., Blackburn, G., Thomas, D., Giraldo, C. V., Biggs, M. J. P., Curtis, A., Salmerón-Sanchez, M., Reid, S. and Dalby, M. (2017) Stimulation of 3D osteogenesis by mesenchymal stem cells via a nanovibrational bioreactor. [Data Collection]