Paula Blair

Research title

The Genetics of Prenatal Diagnosis and Its Social Impact, c1950-c1990: the case of Malcolm Ferguson-Smith

Research summary

Resarch Summary

The 1960s was a decade of major social and cultural change, which was characterised by a decline in religious adherence and advances in many scientific disciplines. The field of genetics was amongst those progressing rapidly, with major technical advances being made. Whilst it had long been recognised that many medical conditions were inherited, it was only in the late 1950s that it became possible to identify specific genetic conditions during pregnancy using prenatal diagnostic testing. In the West of Scotland a key figure involved in developing prenatal testing was Malcolm Ferguson-Smith, who is widely regarded as one of the most eminent British geneticists of recent decades. He played a key role in developing prenatal tests for Down’s syndrome and spina bifida and was also responsible for the establishment of the Duncan Guthrie Institute in Glasgow in 1980, one of the first specialised diagnostic and genetic counselling services for patients in the UK.

 

Ferguson-Smith’s research work often placed him in direct conflict with religious organisations, as the nature of research into the detection of genetic abnormality, enabling elective termination of affected pregnancies, raised ethical issues and concerns which directly conflicted with the views of a number of religious groups and commentators. This project will investigate Ferguson-Smith’s role in the development of prenatal diagnostic testing, and will place his findings in the relevant context of the complex religious-ethical conflicts that arose from his research and its implications.

 

Research Title

The Genetics of Prenatal Diagnosis and Its Social Impact, c1950-c1990: the case of Malcolm Ferguson-Smith

Research Interests

  • Genetics
  • History of medicine
  • History of science
  • Malcolm Ferguson-Smith
  • Prenatal testing
  • Religion

Sponsor / Funder

Economic and Social Research Council

 

 


Publications

Blair, P. (2017) 'Down's syndrome: the story of an extra chromosome 21', Biological Sciences Review, 29 (3), pp. 37-41.


Supervisors

Grants

Fully funded PhD


Teaching

Tutor of Biology in the Centre for Open Studies Access course at the University of Glasgow

Tutor on the Top Up programme, part of Widening Access at the University of Glasgow


Additional information

I began studying for my MSc in History of Medicine at the University of Glasgow in 2014, funded by the Wellcome Trust, and I graduated in December 2015 with Merit.

 

I am now in the third year of studying for my ESRC-funded PhD at the University of Glasgow, which will focus on the development of prenatal diagnostic testing in the West of Scotland, and the response of religious organisations to the testing. I have spoken at a variety of events throughout the course of my PhD so far, including several national and one international conference.