2018

Wyse, C.A., Zhang, X., McLaughlin, M. , Biello, S.M. , Hough, D., Bellingham, M. , Curtis, A.M., Robinson, J.E. and Evans, N.P. (2018) Circadian rhythms of melatonin and behaviour in juvenile sheep in field conditions: effects of photoperiod, environment and weaning. Physiology and Behavior, 194, pp. 362-370. (doi: 10.1016/j.physbeh.2018.06.001) (PMID:29894760)

2017

Tsimbouri, P. M. et al. (2017) Stimulation of 3D osteogenesis by mesenchymal stem cells using a nanovibrational bioreactor. Nature Biomedical Engineering, 1, pp. 758-770. (doi: 10.1038/s41551-017-0127-4) (PMID:31015671)

2016

Nikukar, H., Childs, P. G., Curtis, A. S., Martin, I. W. , Riehle, M. O. , Dalby, M. J. and Reid, S. (2016) Production of nanoscale vibration for stimulation of human mesenchymal stem cells. Journal of Biomedical Nanotechnology, 12(7), pp. 1478-1488. (doi: 10.1166/jbn.2016.2264)

Childs, P. G., Boyle, C., Pemberton, G. D., Nikukar, H., Curtis, A. S.G., Henriquez, F. L., Dalby, M. J. and Reid, S. (2016) Use of nanoscale mechanical stimulation for control and manipulation of cell behaviour. Acta Biomaterialia, 34, pp. 159-168. (doi: 10.1016/j.actbio.2015.11.045) (PMID:6612418))

2015

Nikukar, H., Reid, S., Riehle, M.O. , Curtis, A.S.G. and Dalby, M.J. (2015) Control of mesenchymal stem-cell fate by engineering the nanoenvironment. In: Baharvand, H. and Aghdami, N. (eds.) Stem-Cell Nanoengineering. Wiley Blackwell: Hoboken, NJ, pp. 205-221. ISBN 9781118540619 (doi: 10.1002/9781118540640.ch12)

Pemberton, G. D., Childs, P., Reid, S., Nikukar, H., Tsimbouri, M. , Gadegaard, N. , Curtis, A. S. and Dalby, M. J. (2015) Nanoscale stimulation of osteoblastogenesis from mesenchymal stem cells: nanotopography and nanokicking. Nanomedicine, 10(4), pp. 547-560. (doi: 10.2217/nnm.14.134) (PMID:25723089)

2014

Curtis, A. S. and Tsimbouri, P. M. (2014) Epigenesis: roles of nanotopography, nanoforces and nanovibration. Expert Review of Medical Devices, 11(4), pp. 417-423. (doi: 10.1586/17434440.2014.916205)

2013

Curtis, A. S.G., Reid, S., Martin, I. , Vaidyanathan, R., Smith, C.-A. , Nikukar, H. and Dalby, M. J. (2013) Cell interactions at the nanoscale: piezoelectric stimulation. IEEE Transactions on NanoBioscience, 12(3), pp. 247-254. (doi: 10.1109/TNB.2013.2257837) (PMID:23771395)

Nikukar, H., Reid, S.W.J., Tsimbouri, P.M. , Riehle, M.O. , Curtis, A.S.G. and Dalby, M.J. (2013) Osteogenesis of mesenchymal stem cells by nanoscale mechanotransduction. ACS Nano, 7(3), pp. 2758-2767. (doi: 10.1021/nn400202j)

2012

McNamara, L.E., Burchmore, R.J.S. , Riehle, M.O. , Herzyk, P. , Biggs, M.J.P., Wilkinson, C.D.W., Curtis, A.S.G. and Dalby, M.J. (2012) The role of microtopography in cellular mechanotransduction. Biomaterials, 33(10), pp. 2835-2847. (doi: 10.1016/j.biomaterials.2011.11.047)

2009

Seunarine, K., Curtis, A.S.G., Meredith, D.O., Wilkinson, C.D.W., Riehle, M.O. and Gadegaard, N. (2009) A hierarchical response of cells to perpendicular micro- and nanometric textural cues. IEEE Transactions on NanoBioscience, 8(3), pp. 219-225. (doi: 10.1109/TNB.2009.2016477)

Beattie, A.J., Curtis, A.S.G., Wilkinson, C.D.W. and Riehle, M.O. (2009) Nanomaterials for neural interfaces: emerging new function and potential applications. In: Offenhausser, A. and Rinaldi, R. (eds.) Nanoelectronics - for Electronics, Biology, and Medicine. Series: Nanostructure Science and Technology. Springer: New York, USA, pp. 277-286. ISBN 9780387094598 (doi: 10.1007/978-0-387-09459-5)

2008

Martines, E., Csaderova, L., Morgan, H., Curtis, A.S.G. and Riehle, M.O. (2008) DLVO interaction energy between a sphere and a nano-patterned plate. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 318(1-3), pp. 45-52. (doi: 10.1016/j.colsurfa.2007.11.035)

2007

Curtis, A., Sokolikova-Csaderova, L. and Aitchison, G. (2007) Measuring cell forces by a photoelastic method. Biophysical Journal, 92(6), pp. 2255-2261. (doi: 10.1529/biophysj.106.088849)

Berry, C.C. , Curtis, A.S.G., Oreffo, R.O.C., Agheli, H. and Sutherland, D.S. (2007) Human fibroblast and human bone marrow cell response to lithographically nanopatterned adhesive domains on protein rejecting substrates. IEEE Transactions on NanoBioscience, 6(3), pp. 201-209. (doi: 10.1109/TNB.2007.903457)

Dalby, M.J. , Biggs, M.J.P., Gadegaard, N. , Kalna, G., Wilkinson, C.D.W. and Curtis, A.S.G. (2007) Nanotopographical stimulation of mechanotransduction and changes in interphase centromere positioning. Journal of Cellular Biochemistry, 100, pp. 326-338. (doi: 10.1002/jcb.21058)

Meredith, D., Eschbach, L., Riehle, M. , Curtis, A. and Richards, R. (2007) Microtopography of metal surfaces influence fibroblast growth by modifying cell shape, cytoskeleton, and adhesion. Journal of Orthopaedic Research, 25, pp. 1523-1533. (doi: 10.1002/jor.20430)

Meredith, D., Riehle, M. , Curtis, A. and Richards, R. (2007) Is surface chemical composition important for orthopaedic implant materials? Journal of Materials Science: Materials in Medicine, 18, pp. 405-413. (doi: 10.1007/s10856-006-0706-5)

2006

Curtis, A., Aitchison, G. and Tsapikouni, T. (2006) Orthogonal (transverse) arrangements of actin in endothelia and fibroblasts. Journal of the Royal Society: Interface, 3, pp. 753-756. (doi: 10.1098/rsif.2006.0132)

Curtis, A.S.G., Dalby, M.J. and Gadegaard, N. (2006) Cell signaling arising from nanotopography: implications for nanomedical devices. Nanomedicine, 1, pp. 67-72. (doi: 10.2217/17435889.1.1.67)

Curtis, A., Dalby, M. and Gadegaard, N. (2006) Nanoprinting onto cells. Journal of the Royal Society: Interface, 3, pp. 393-398. (doi: 10.1098/rsif.2005.0104)

de la Fuente, J., Berry, C., Riehle, M.O. and Curtis, A. (2006) Nanoparticle targeting at cells. Langmuir, 22, pp. 3286-3293. (doi: 10.1021/la053029v)

Hamilton, D., Riehle, M.O. , Monaghan, W. and Curtis, A. (2006) Chondrocyte aggregation on micrometric surface topography: A time-lapse study. Tissue Engineering, 12, pp. 189-199.

Johnson, W., Wootton, A., El Haj, A., Eisenstein, S., Curtis, A. and Roberts, S. (2006) Topographical guidance of intervertebral disc cell growth in vitro: towards the development of tissue repair strategies for the anulus fibrosus. European Spine Journal, 15, S389-S396. (doi: 10.1007/s00586-006-0125-9)

Lecomte, H.A., Liggat, J.J. and Curtis, A.S.G. (2006) Synthesis and characterization of novel biodegradable aliphatic poly(ester amide)s containing cyclohexane units. Journal of Polymer Science Part A: Polymer Chemistry, 44, pp. 1785-1795. (doi: 10.1002/pola.21288)

2005

Curtis, A. (2005) Cell forces in tissues. Medical Engineering and Physics, 27(9), pp. 773-779. (doi: 10.1016/j.medengphy.2005.04.004)

Riehle, M. and Curtis, A.S.G. (2005) Effects of mechanical forces engineering reactions at the cellular level. Medical Engineering and Physics, 27(9), p. 729. (doi: 10.1016/j.medengphy.2005.04.003)

de la Fuente, J.M., Fandel, M., Berry, C.C. , Riehle, M. , Cronin, L. , Aitchison, G. and Curtis, A.S.G. (2005) Quantum dots protected with tiopronin: a new fluorescence system for cell-biology studies. ChemBioChem, 6(6), pp. 989-991. (doi: 10.1002/cbic.200500071)

Jorgensen, H.G. , McLellan, S., Crossan, J. and Curtis, A.S.G. (2005) Neutralisation of TGFβ or binding of VLA-4 to fibronectin prevents rat tendon adhesion following transection. Cytokine, 30(4), pp. 195-202. (doi: 10.1016/j.cyto.2004.12.017)

Curtis, A. (2005) The potential for the use of nanofeaturing in medical devices. Expert Review of Medical Devices, 2, pp. 293-301. (doi: 10.1586/17434440.2.3.293)

Curtis, A.S.G., Wilkinson, C.D.W., Crossan, J., Broadley, C., Darmani, H., Johal, K.K., Jorgensen, H. and Monaghan, W. (2005) An in vivo microfabricated scaffold for tendon repair. European Cells and Materials, 9, pp. 50-57.

Dalby, M.J. , Riehle, M.O. , Sutherland, D.S., Agheli, H. and Curtis, A.S.G. (2005) Morphological and microarray analysis of human fibroblasts cultured on nanocolumns produced by colloidal lithography. European Cells and Materials, 9, pp. 1-8.

Hamilton, D., Riehle, M.O. , Monaghan, W. and Curtis, A. (2005) Articular chondrocyte passage number: Influence on adhesion, migration, cytoskeletal organisation and phenotype in response to nano- and micro-metric topography. Cell Biology International, 29, pp. 408-421. (doi: 10.1016/j.cellbi.2004.12.008)

Hamilton, D., Riehle, M.O. , Rappuoli, R., Monaghan, W., Barbucci, R. and Curtis, A. (2005) The response of primary articular chondrocytes to micrometric surface topography and sulphated hyaluronic acid-based matrices. Cell Biology International, 29, pp. 605-615. (doi: 10.1016/j.cellbi.2005.03.013)

Jorgensen, H., McLellan, S., Crossan, J. and Curtis, A. (2005) Neutralisation of TGF beta or binding of VLA-4 to fibronectin prevents rat tendon adhesion following transection. Cytokine, 30, pp. 195-202. (doi: 10.1016/j.cyto.2004.12.017)

Meredith, D., Eschbach, L., Wood, M., Riehle, M.O. , Curtis, A. and Richards, R. (2005) Human fibroblast reactions to standard and electropolished titanium and Ti-6Al-7Nb, and electropolished stainless steel. Journal of Biomedical Materials Research Part A, 75A, pp. 541-555. (doi: 10.1002/jbm.a.30457)

Ruggiero, C., Mantelli, M., Curtis, A. and Rolfe, P. (2005) Protein-surface interactions - An energy-based mathematical model. Cell Biochemistry and Biophysics, 43, pp. 407-417.

2004

Curtis, A.S.G. (2004) Tutorial on the biology of nanotopography. IEEE Transactions on NanoBioscience, 3(4), pp. 293-295. (doi: 10.1109/TNB.2004.837898)

Berry, C. , Campbell, G., Spadiccino, A., Robertson, M. and Curtis, A.S.G. (2004) The influence of microscale topography on fibroblast attachment and motility. Biomaterials, 25(26), pp. 5781-5788. (doi: 10.1016/j.biomaterials.2004.01.029)

Gadegaard, N. , Dalby, M.J. , Riehle, M.O. , Curtis, A.S.G. and Affrossman, S. (2004) Tubes with controllable internal nanotopography. Advanced Materials, 20, pp. 1857-1860. (doi: 10.1002/adma.200400408)

Berry, C.C. , Wells, S., Charles, S., Aitchison, G. and Curtis, A.S.G. (2004) Cell response to dextran-derivatised iron oxide nanoparticles post internalisation. Biomaterials, 25(23), pp. 5405-5413. (doi: 10.1016/j.biomaterials.2003.12.046)

Dalby, M.J. , Gadegaard, N. , Riehle, M.O. , Wilkinson, C.D.W. and Curtis, A.S.G. (2004) Investigating filopodia sensing using arrays of defined nano-pits down to 35 nm diameter in size. International Journal of Biochemistry and Cell Biology, 36(10), pp. 2005-2015. (doi: 10.1016/j.biocel.2004.03.001)

Dalby, M.J. , Riehle, M.O. , Sutherland, D.S., Agheli, H. and Curtis, A.S.G. (2004) Changes in fibroblast morphology in response to nano-columns produced by colloidal lithography. Biomaterials, 25(23), pp. 5415-5422. (doi: 10.1016/j.biomaterials.2003.12.049) (PMID:15130726)

Martines, E., McGhee, K., Wilkinson, C. and Curtis, A.S.G. (2004) A parallel-plate flow chamber to study initial cell adhesion on a nanofeatured surface. IEEE Transactions on NanoBioscience, 3(2), pp. 90-95. (doi: 10.1109/TNB.2004.828268)

Dalby, M.J. , Berry, C.C. , Riehle, M.O. , Sutherland, D.S., Agheli, H. and Curtis, A.S.G. (2004) Attempted endocytosis of nano-environment produced by colloidal lithography by human fibroblasts. Experimental Cell Research, 295(2), pp. 387-394. (doi: 10.1016/j.yexcr.2004.02.004)

Mikhaylova, M., Kim, D.K., Berry, C.C. , Zagorodni, A., Toprak, M., Curtis, A.S.G. and Muhammed, M. (2004) BSA immobilization on amine-functionalized superparamagnetic iron oxide nanoparticles. Chemistry of Materials, 16(12), pp. 2344-2354. (doi: 10.1021/cm0348904)

Gupta, A.K. and Curtis, A.S.G. (2004) Surface modified superparamagnetic nanoparticles for drug delivery: interaction studies with human fibroblasts in culture. Journal of Materials Science: Materials in Medicine, 15(4), pp. 493-496. (doi: 10.1023/B:JMSM.0000021126.32934.20)

Dalby, M.J. , Riehle, M.O. , Sutherland, D.S., Agheli, H. and Curtis, A.S.G. (2004) Fibroblast response to a controlled nanoenvironment produced by colloidal lithography. Journal of Biomedical Materials Research Part A, 69A(2), pp. 314-322. (doi: 10.1002/jbm.a.20138)

Berry, C.C. , Charles, S., Wells, S., Dalby, M.J. and Curtis, A.S.G. (2004) The influence of transferrin stabilised magnetic nanoparticles on human dermal fibroblasts in culture. International Journal of Pharmaceutics, 269(1), pp. 211-225. (doi: 10.1016/j.ijpharm.2003.09.042)

Dalby, M.J. , Giannaras, D., Riehle, M.O. , Gadegaard, N. , Affrossman, S. and Curtis, A.S.G. (2004) Rapid fibroblast adhesion to 27 nm high polymer demixed nano-topography. Biomaterials, 25(1), pp. 77-83. (doi: 10.1016/S0142-9612(03)00475-7)

Curtis, A.S.G., Gadegaard, N. , Dalby, M.J. , Riehle, M.O. , Wilkinson, C.D.W. and Aitchison, G. (2004) Cells react to nanoscale order and symmetry in their surroundings. IEEE Transactions on NanoBioscience, 3(1), pp. 61-65. (doi: 10.1109/TNB.2004.824276)

Dalby, M.J. , Riehle, M.O. , Johnstone, H., Affrossman, S. and Curtis, A.S.G. (2004) Investigating the limits of filopodial sensing: a brief report using SEM to image the interaction between 10 nm high nano-topography and fibroblast filopodia. Cell Biology International, 28(3), pp. 229-236. (doi: 10.1016/j.cellbi.2003.12.004)

Dalby, M.J. , Riehle, M.O. , Sutherland, D.S., Agheli, H. and Curtis, A.S.G. (2004) Use of nanotopography to study mechanotransduction in fibroblasts – methods and perspectives. European Journal of Cell Biology, 83(4), pp. 159-169. (doi: 10.1078/0171-9335-00369)

Darmani, H., Crossan, J., McLellan, S., Meek, D. and Curtis, A. (2004) Expression of nitric oxide synthase and transforming growth factor-beta in crush-injured tendon and synovium. Mediators of Inflammation, 13, pp. 299-305. (doi: 10.1080/09629350400008844)

Darmani, H., Crossan, J. and Curtis, A. (2004) Single dose of inducible nitric oxide synthase inhibitor induces prolonged inflammatory cell accumulation and fibrosis around injured tendon and synovium. Mediators of Inflammation, 13, pp. 157-164. (doi: 10.1080/09511920410001713556)

Darmani, H., Crossan, J., Mclellan, S.D., Meek, D. and Curtis, A.S.G. (2004) Expression of nitric oxide synthase and transforming growth factor-beta in crush-injured tendon and synovium. Mediators of Inflammation, 13(5-6), pp. 299-305. (doi: 10.1080/09629350400008844)

Darmani, H., Crossan, J.C. and Curtis, A. (2004) Single dose of inducible nitric oxide synthase inhibitor induces prolonged inflammatory cell accumulation and fibrosis around injured tendon and synovium. Mediators of Inflammation, 13(3), pp. 157-164. (doi: 10.1080/09511920410001713556)

Gupta, A. and Curtis, A. (2004) Lactoferrin and ceruloplasmin derivatized superparamagnetic iron oxide nanoparticles for targeting cell surface receptors. Biomaterials, 25, pp. 3029-3040. (doi: 10.1016/j.biomaterials.2003.09.095)

Gupta, A., Gupta, M., Yarwood, S. and Curtis, A. (2004) Effect of cellular uptake of gelatin nanoparticles on adhesion, morphology and cytoskeleton organisation of human fibroblasts. Journal of Controlled Release, 95, pp. 197-207. (doi: 10.1016/j.jconrel.2003.11.006)

Mikhaylova, M., Berry, C.C. , Kim, D.K., Jo, Y.S., Curtis, A.S.G. and Muhammed, M. (2004) In vitro reaction of human fibroblasts with gold – and L-aspartic acid – functionalized superparamagnetic iron oxide nanoparticles. Annals of Transplantation, 9(Sup 1A), pp. 79-81.

2003

Gupta, A.K., Berry, C.C. , Gupta, M. and Curtis, A.S.G. (2003) Receptor-mediated targeting of magnetic nanoparticles using insulin as a surface ligand to prevent endocytosis. IEEE Transactions on NanoBioscience, 2(4), pp. 255-261. (doi: 10.1109/TNB.2003.820279)

Berry, C.C. , Wells, S., Charles, S. and Curtis, A.S.G. (2003) Dextran and albumin derivatised iron oxide nanoparticles: influence on fibroblasts in vitro. Biomaterials, 24(25), pp. 4551-4557. (doi: 10.1016/S0142-9612(03)00237-0)

Dalby, M.J. , Riehle, M.O. , Johnstone, H.J.H., Affrossman, S. and Curtis, A.S.G. (2003) Nonadhesive nanotopography: fibroblast response to poly(n-butyl methacrylate)-poly(styrene) demixed surface features. Journal of Biomedical Materials Research Part A, 67A(3), pp. 1025-1032. (doi: 10.1002/jbm.a.10139)

Dalby, M.J. , Riehle, M.O. , Yarwood, S.J., Wilkinson, C.D.W. and Curtis, A.S.G. (2003) Nucleus alignment and cell signaling in fibroblasts: response to a micro-grooved topography. Experimental Cell Research, 284(2), pp. 272-280. (doi: 10.1016/S0014-4827(02)00053-8)

Barbucci, R., Pasqui, D., Wirsen, A., Affrossman, S., Curtis, A. and Tetta, C. (2003) Micro and nano-structured surfaces. Journal of Materials Science: Materials in Medicine, 14, pp. 721-725.

Berry, C.C. and Curtis, A.S.G. (2003) Functionalisation of magnetic nanoparticles for applications in biomedicine. Journal of Physics D: Applied Physics, 36(13), R198-R206. (doi: 10.1088/0022-3727/36/13/203)

Curtis, A.S.G. (2003) Biomedical aspects of magnetic nanoparticles. Europhysics News, 34(6), (doi: 10.1051/epn:2003602)

Dalby, M., Childs, S., Riehle, M.O. , Johnstone, H., Affrossman, S. and Curtis, A. (2003) Fibroblast reaction to island topography: changes in cytoskeleton and morphology with time. Biomaterials, 24, pp. 927-935.

Wilkinson, C.D.W., Thoms, S. , Macintyre, D., Curtis, A.S.G., Riehle, M. and Gadegaard, N. (2003) Nanofabrication of structures for cell engineering. Proceedings of the SPIE: The International Society for Optical Engineering, 5220, pp. 1-9. (doi: 10.1117/12.509749)

2002

Curtis, A. (2002) Materials science: Breaking the neural code. Nature, 416(6878), pp. 274-275. (doi: 10.1038/416274a)

Berry, C.C. , Rudershausen, S., Teller, J. and Curtis, A.S.G. (2002) The influence of elastin-coated 520-nm- and 20-nm-diameter nanoparticles on human fibroblasts in vitro. IEEE Transactions on NanoBioscience, 1(3), pp. 105-109. (doi: 10.1109/TNB.2003.809467)

Dalby, M.J. , Riehle, M.O. , Johnstone, H., Affrossman, S. and Curtis, A. (2002) Polymer-demixed nanotopography: Control of fibroblast spreading and proliferation. Tissue Engineering, 8, pp. 1099-1108.

Dalby, M., Riehle, M.O. , Johnstone, H., Affrossman, S. and Curtis, A. (2002) In vitro reaction of endothelial cells to polymer demixed nanotopography. Biomaterials, 23, pp. 2945-2954.

Federle, W., Riehle, M. , Curtis, A. and Full, R. (2002) An integrative study of insect adhesion: Mechanics and wet adhesion of pretarsal pads in ants. Integrative and Comparative Biology, 42, pp. 1100-1106.

Sandison, M., Curtis, A. and Wilkinson, C. (2002) Effective extra-cellular recording from vertebrate neurons in culture using a new type of micro-electrode array. Journal of Neuroscience Methods, 114, pp. 63-71.

Wilkinson, C.D.W., Riehle, M. , Wood, M., Gallagher, J. and Curtis, A.S.G. (2002) The use of materials patterned on a nano- and micro-metric scale in cellular engineering. Materials Science and Engineering C: Biomimetic and Supramolecular Systems, 19(1-2), pp. 263-269. (doi: 10.1016/S0928-4931(01)00396-4)

2001

Curtis, A. and Riehle, M. (2001) Tissue engineering: the biophysical background. Physics in Medicine and Biology, 46, R47-R65.

Curtis, A., Casey, B., Gallagher, J., Pasqui, D., Wood, M. and Wilkinson, C. (2001) Substratum nanotopography and the adhesion of biological cells. Are symmetry or regularity of nanotopography important? Biophysical Chemistry, 94, pp. 275-283.

Morgan, H., Riehle, M. and Curtis, A.S.G. (2001) Surface plasmon resonance analysis of cell substrate interaction. In: 42nd Conference of the Society of Experimental Biology, Canterbury, UK,

Richards, R., Stiffanic, M., Owen, G., Riehle, M. , Gwynn, I. and Curtis, A. (2001) Immunogold labelling of fibroblast focal adhesion sites visualised in fixed material using scanning electron microscopy, and living, using internal reflection microscopy. Cell Biology International, 25, pp. 1237-1249. (doi: 10.1006/cbir.2001.0807)

Zhang, T., Morgan, H., Curtis, A. and Riehle, M. (2001) Measuring particle-substrate distance with surface plasmon resonance microscopy. Journal of Optics A: Pure and Applied Optics, 3, pp. 333-337.

1992

Goodall, C. and Curtis, A. (1992) Modulation of adhesion of lymphocytes to murine brain endothelial cells in vitro: relation to class II major histocompatibility complex expression. Journal of Neuroimmunology, 37(1-2), pp. 9-22. (doi: 10.1016/0165-5728(92)90151-A)

Articles

Wyse, C.A., Zhang, X., McLaughlin, M. , Biello, S.M. , Hough, D., Bellingham, M. , Curtis, A.M., Robinson, J.E. and Evans, N.P. (2018) Circadian rhythms of melatonin and behaviour in juvenile sheep in field conditions: effects of photoperiod, environment and weaning. Physiology and Behavior, 194, pp. 362-370. (doi: 10.1016/j.physbeh.2018.06.001) (PMID:29894760)

Tsimbouri, P. M. et al. (2017) Stimulation of 3D osteogenesis by mesenchymal stem cells using a nanovibrational bioreactor. Nature Biomedical Engineering, 1, pp. 758-770. (doi: 10.1038/s41551-017-0127-4) (PMID:31015671)

Nikukar, H., Childs, P. G., Curtis, A. S., Martin, I. W. , Riehle, M. O. , Dalby, M. J. and Reid, S. (2016) Production of nanoscale vibration for stimulation of human mesenchymal stem cells. Journal of Biomedical Nanotechnology, 12(7), pp. 1478-1488. (doi: 10.1166/jbn.2016.2264)

Childs, P. G., Boyle, C., Pemberton, G. D., Nikukar, H., Curtis, A. S.G., Henriquez, F. L., Dalby, M. J. and Reid, S. (2016) Use of nanoscale mechanical stimulation for control and manipulation of cell behaviour. Acta Biomaterialia, 34, pp. 159-168. (doi: 10.1016/j.actbio.2015.11.045) (PMID:6612418))

Pemberton, G. D., Childs, P., Reid, S., Nikukar, H., Tsimbouri, M. , Gadegaard, N. , Curtis, A. S. and Dalby, M. J. (2015) Nanoscale stimulation of osteoblastogenesis from mesenchymal stem cells: nanotopography and nanokicking. Nanomedicine, 10(4), pp. 547-560. (doi: 10.2217/nnm.14.134) (PMID:25723089)

Curtis, A. S. and Tsimbouri, P. M. (2014) Epigenesis: roles of nanotopography, nanoforces and nanovibration. Expert Review of Medical Devices, 11(4), pp. 417-423. (doi: 10.1586/17434440.2014.916205)

Curtis, A. S.G., Reid, S., Martin, I. , Vaidyanathan, R., Smith, C.-A. , Nikukar, H. and Dalby, M. J. (2013) Cell interactions at the nanoscale: piezoelectric stimulation. IEEE Transactions on NanoBioscience, 12(3), pp. 247-254. (doi: 10.1109/TNB.2013.2257837) (PMID:23771395)

Nikukar, H., Reid, S.W.J., Tsimbouri, P.M. , Riehle, M.O. , Curtis, A.S.G. and Dalby, M.J. (2013) Osteogenesis of mesenchymal stem cells by nanoscale mechanotransduction. ACS Nano, 7(3), pp. 2758-2767. (doi: 10.1021/nn400202j)

McNamara, L.E., Burchmore, R.J.S. , Riehle, M.O. , Herzyk, P. , Biggs, M.J.P., Wilkinson, C.D.W., Curtis, A.S.G. and Dalby, M.J. (2012) The role of microtopography in cellular mechanotransduction. Biomaterials, 33(10), pp. 2835-2847. (doi: 10.1016/j.biomaterials.2011.11.047)

Seunarine, K., Curtis, A.S.G., Meredith, D.O., Wilkinson, C.D.W., Riehle, M.O. and Gadegaard, N. (2009) A hierarchical response of cells to perpendicular micro- and nanometric textural cues. IEEE Transactions on NanoBioscience, 8(3), pp. 219-225. (doi: 10.1109/TNB.2009.2016477)

Martines, E., Csaderova, L., Morgan, H., Curtis, A.S.G. and Riehle, M.O. (2008) DLVO interaction energy between a sphere and a nano-patterned plate. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 318(1-3), pp. 45-52. (doi: 10.1016/j.colsurfa.2007.11.035)

Curtis, A., Sokolikova-Csaderova, L. and Aitchison, G. (2007) Measuring cell forces by a photoelastic method. Biophysical Journal, 92(6), pp. 2255-2261. (doi: 10.1529/biophysj.106.088849)

Berry, C.C. , Curtis, A.S.G., Oreffo, R.O.C., Agheli, H. and Sutherland, D.S. (2007) Human fibroblast and human bone marrow cell response to lithographically nanopatterned adhesive domains on protein rejecting substrates. IEEE Transactions on NanoBioscience, 6(3), pp. 201-209. (doi: 10.1109/TNB.2007.903457)

Dalby, M.J. , Biggs, M.J.P., Gadegaard, N. , Kalna, G., Wilkinson, C.D.W. and Curtis, A.S.G. (2007) Nanotopographical stimulation of mechanotransduction and changes in interphase centromere positioning. Journal of Cellular Biochemistry, 100, pp. 326-338. (doi: 10.1002/jcb.21058)

Meredith, D., Eschbach, L., Riehle, M. , Curtis, A. and Richards, R. (2007) Microtopography of metal surfaces influence fibroblast growth by modifying cell shape, cytoskeleton, and adhesion. Journal of Orthopaedic Research, 25, pp. 1523-1533. (doi: 10.1002/jor.20430)

Meredith, D., Riehle, M. , Curtis, A. and Richards, R. (2007) Is surface chemical composition important for orthopaedic implant materials? Journal of Materials Science: Materials in Medicine, 18, pp. 405-413. (doi: 10.1007/s10856-006-0706-5)

Curtis, A., Aitchison, G. and Tsapikouni, T. (2006) Orthogonal (transverse) arrangements of actin in endothelia and fibroblasts. Journal of the Royal Society: Interface, 3, pp. 753-756. (doi: 10.1098/rsif.2006.0132)

Curtis, A.S.G., Dalby, M.J. and Gadegaard, N. (2006) Cell signaling arising from nanotopography: implications for nanomedical devices. Nanomedicine, 1, pp. 67-72. (doi: 10.2217/17435889.1.1.67)

Curtis, A., Dalby, M. and Gadegaard, N. (2006) Nanoprinting onto cells. Journal of the Royal Society: Interface, 3, pp. 393-398. (doi: 10.1098/rsif.2005.0104)

de la Fuente, J., Berry, C., Riehle, M.O. and Curtis, A. (2006) Nanoparticle targeting at cells. Langmuir, 22, pp. 3286-3293. (doi: 10.1021/la053029v)

Hamilton, D., Riehle, M.O. , Monaghan, W. and Curtis, A. (2006) Chondrocyte aggregation on micrometric surface topography: A time-lapse study. Tissue Engineering, 12, pp. 189-199.

Johnson, W., Wootton, A., El Haj, A., Eisenstein, S., Curtis, A. and Roberts, S. (2006) Topographical guidance of intervertebral disc cell growth in vitro: towards the development of tissue repair strategies for the anulus fibrosus. European Spine Journal, 15, S389-S396. (doi: 10.1007/s00586-006-0125-9)

Lecomte, H.A., Liggat, J.J. and Curtis, A.S.G. (2006) Synthesis and characterization of novel biodegradable aliphatic poly(ester amide)s containing cyclohexane units. Journal of Polymer Science Part A: Polymer Chemistry, 44, pp. 1785-1795. (doi: 10.1002/pola.21288)

Curtis, A. (2005) Cell forces in tissues. Medical Engineering and Physics, 27(9), pp. 773-779. (doi: 10.1016/j.medengphy.2005.04.004)

Riehle, M. and Curtis, A.S.G. (2005) Effects of mechanical forces engineering reactions at the cellular level. Medical Engineering and Physics, 27(9), p. 729. (doi: 10.1016/j.medengphy.2005.04.003)

de la Fuente, J.M., Fandel, M., Berry, C.C. , Riehle, M. , Cronin, L. , Aitchison, G. and Curtis, A.S.G. (2005) Quantum dots protected with tiopronin: a new fluorescence system for cell-biology studies. ChemBioChem, 6(6), pp. 989-991. (doi: 10.1002/cbic.200500071)

Jorgensen, H.G. , McLellan, S., Crossan, J. and Curtis, A.S.G. (2005) Neutralisation of TGFβ or binding of VLA-4 to fibronectin prevents rat tendon adhesion following transection. Cytokine, 30(4), pp. 195-202. (doi: 10.1016/j.cyto.2004.12.017)

Curtis, A. (2005) The potential for the use of nanofeaturing in medical devices. Expert Review of Medical Devices, 2, pp. 293-301. (doi: 10.1586/17434440.2.3.293)

Curtis, A.S.G., Wilkinson, C.D.W., Crossan, J., Broadley, C., Darmani, H., Johal, K.K., Jorgensen, H. and Monaghan, W. (2005) An in vivo microfabricated scaffold for tendon repair. European Cells and Materials, 9, pp. 50-57.

Dalby, M.J. , Riehle, M.O. , Sutherland, D.S., Agheli, H. and Curtis, A.S.G. (2005) Morphological and microarray analysis of human fibroblasts cultured on nanocolumns produced by colloidal lithography. European Cells and Materials, 9, pp. 1-8.

Hamilton, D., Riehle, M.O. , Monaghan, W. and Curtis, A. (2005) Articular chondrocyte passage number: Influence on adhesion, migration, cytoskeletal organisation and phenotype in response to nano- and micro-metric topography. Cell Biology International, 29, pp. 408-421. (doi: 10.1016/j.cellbi.2004.12.008)

Hamilton, D., Riehle, M.O. , Rappuoli, R., Monaghan, W., Barbucci, R. and Curtis, A. (2005) The response of primary articular chondrocytes to micrometric surface topography and sulphated hyaluronic acid-based matrices. Cell Biology International, 29, pp. 605-615. (doi: 10.1016/j.cellbi.2005.03.013)

Jorgensen, H., McLellan, S., Crossan, J. and Curtis, A. (2005) Neutralisation of TGF beta or binding of VLA-4 to fibronectin prevents rat tendon adhesion following transection. Cytokine, 30, pp. 195-202. (doi: 10.1016/j.cyto.2004.12.017)

Meredith, D., Eschbach, L., Wood, M., Riehle, M.O. , Curtis, A. and Richards, R. (2005) Human fibroblast reactions to standard and electropolished titanium and Ti-6Al-7Nb, and electropolished stainless steel. Journal of Biomedical Materials Research Part A, 75A, pp. 541-555. (doi: 10.1002/jbm.a.30457)

Ruggiero, C., Mantelli, M., Curtis, A. and Rolfe, P. (2005) Protein-surface interactions - An energy-based mathematical model. Cell Biochemistry and Biophysics, 43, pp. 407-417.

Curtis, A.S.G. (2004) Tutorial on the biology of nanotopography. IEEE Transactions on NanoBioscience, 3(4), pp. 293-295. (doi: 10.1109/TNB.2004.837898)

Berry, C. , Campbell, G., Spadiccino, A., Robertson, M. and Curtis, A.S.G. (2004) The influence of microscale topography on fibroblast attachment and motility. Biomaterials, 25(26), pp. 5781-5788. (doi: 10.1016/j.biomaterials.2004.01.029)

Gadegaard, N. , Dalby, M.J. , Riehle, M.O. , Curtis, A.S.G. and Affrossman, S. (2004) Tubes with controllable internal nanotopography. Advanced Materials, 20, pp. 1857-1860. (doi: 10.1002/adma.200400408)

Berry, C.C. , Wells, S., Charles, S., Aitchison, G. and Curtis, A.S.G. (2004) Cell response to dextran-derivatised iron oxide nanoparticles post internalisation. Biomaterials, 25(23), pp. 5405-5413. (doi: 10.1016/j.biomaterials.2003.12.046)

Dalby, M.J. , Gadegaard, N. , Riehle, M.O. , Wilkinson, C.D.W. and Curtis, A.S.G. (2004) Investigating filopodia sensing using arrays of defined nano-pits down to 35 nm diameter in size. International Journal of Biochemistry and Cell Biology, 36(10), pp. 2005-2015. (doi: 10.1016/j.biocel.2004.03.001)

Dalby, M.J. , Riehle, M.O. , Sutherland, D.S., Agheli, H. and Curtis, A.S.G. (2004) Changes in fibroblast morphology in response to nano-columns produced by colloidal lithography. Biomaterials, 25(23), pp. 5415-5422. (doi: 10.1016/j.biomaterials.2003.12.049) (PMID:15130726)

Martines, E., McGhee, K., Wilkinson, C. and Curtis, A.S.G. (2004) A parallel-plate flow chamber to study initial cell adhesion on a nanofeatured surface. IEEE Transactions on NanoBioscience, 3(2), pp. 90-95. (doi: 10.1109/TNB.2004.828268)

Dalby, M.J. , Berry, C.C. , Riehle, M.O. , Sutherland, D.S., Agheli, H. and Curtis, A.S.G. (2004) Attempted endocytosis of nano-environment produced by colloidal lithography by human fibroblasts. Experimental Cell Research, 295(2), pp. 387-394. (doi: 10.1016/j.yexcr.2004.02.004)

Mikhaylova, M., Kim, D.K., Berry, C.C. , Zagorodni, A., Toprak, M., Curtis, A.S.G. and Muhammed, M. (2004) BSA immobilization on amine-functionalized superparamagnetic iron oxide nanoparticles. Chemistry of Materials, 16(12), pp. 2344-2354. (doi: 10.1021/cm0348904)

Gupta, A.K. and Curtis, A.S.G. (2004) Surface modified superparamagnetic nanoparticles for drug delivery: interaction studies with human fibroblasts in culture. Journal of Materials Science: Materials in Medicine, 15(4), pp. 493-496. (doi: 10.1023/B:JMSM.0000021126.32934.20)

Dalby, M.J. , Riehle, M.O. , Sutherland, D.S., Agheli, H. and Curtis, A.S.G. (2004) Fibroblast response to a controlled nanoenvironment produced by colloidal lithography. Journal of Biomedical Materials Research Part A, 69A(2), pp. 314-322. (doi: 10.1002/jbm.a.20138)

Berry, C.C. , Charles, S., Wells, S., Dalby, M.J. and Curtis, A.S.G. (2004) The influence of transferrin stabilised magnetic nanoparticles on human dermal fibroblasts in culture. International Journal of Pharmaceutics, 269(1), pp. 211-225. (doi: 10.1016/j.ijpharm.2003.09.042)

Dalby, M.J. , Giannaras, D., Riehle, M.O. , Gadegaard, N. , Affrossman, S. and Curtis, A.S.G. (2004) Rapid fibroblast adhesion to 27 nm high polymer demixed nano-topography. Biomaterials, 25(1), pp. 77-83. (doi: 10.1016/S0142-9612(03)00475-7)

Curtis, A.S.G., Gadegaard, N. , Dalby, M.J. , Riehle, M.O. , Wilkinson, C.D.W. and Aitchison, G. (2004) Cells react to nanoscale order and symmetry in their surroundings. IEEE Transactions on NanoBioscience, 3(1), pp. 61-65. (doi: 10.1109/TNB.2004.824276)

Dalby, M.J. , Riehle, M.O. , Johnstone, H., Affrossman, S. and Curtis, A.S.G. (2004) Investigating the limits of filopodial sensing: a brief report using SEM to image the interaction between 10 nm high nano-topography and fibroblast filopodia. Cell Biology International, 28(3), pp. 229-236. (doi: 10.1016/j.cellbi.2003.12.004)

Dalby, M.J. , Riehle, M.O. , Sutherland, D.S., Agheli, H. and Curtis, A.S.G. (2004) Use of nanotopography to study mechanotransduction in fibroblasts – methods and perspectives. European Journal of Cell Biology, 83(4), pp. 159-169. (doi: 10.1078/0171-9335-00369)

Darmani, H., Crossan, J., McLellan, S., Meek, D. and Curtis, A. (2004) Expression of nitric oxide synthase and transforming growth factor-beta in crush-injured tendon and synovium. Mediators of Inflammation, 13, pp. 299-305. (doi: 10.1080/09629350400008844)

Darmani, H., Crossan, J. and Curtis, A. (2004) Single dose of inducible nitric oxide synthase inhibitor induces prolonged inflammatory cell accumulation and fibrosis around injured tendon and synovium. Mediators of Inflammation, 13, pp. 157-164. (doi: 10.1080/09511920410001713556)

Darmani, H., Crossan, J., Mclellan, S.D., Meek, D. and Curtis, A.S.G. (2004) Expression of nitric oxide synthase and transforming growth factor-beta in crush-injured tendon and synovium. Mediators of Inflammation, 13(5-6), pp. 299-305. (doi: 10.1080/09629350400008844)

Darmani, H., Crossan, J.C. and Curtis, A. (2004) Single dose of inducible nitric oxide synthase inhibitor induces prolonged inflammatory cell accumulation and fibrosis around injured tendon and synovium. Mediators of Inflammation, 13(3), pp. 157-164. (doi: 10.1080/09511920410001713556)

Gupta, A. and Curtis, A. (2004) Lactoferrin and ceruloplasmin derivatized superparamagnetic iron oxide nanoparticles for targeting cell surface receptors. Biomaterials, 25, pp. 3029-3040. (doi: 10.1016/j.biomaterials.2003.09.095)

Gupta, A., Gupta, M., Yarwood, S. and Curtis, A. (2004) Effect of cellular uptake of gelatin nanoparticles on adhesion, morphology and cytoskeleton organisation of human fibroblasts. Journal of Controlled Release, 95, pp. 197-207. (doi: 10.1016/j.jconrel.2003.11.006)

Mikhaylova, M., Berry, C.C. , Kim, D.K., Jo, Y.S., Curtis, A.S.G. and Muhammed, M. (2004) In vitro reaction of human fibroblasts with gold – and L-aspartic acid – functionalized superparamagnetic iron oxide nanoparticles. Annals of Transplantation, 9(Sup 1A), pp. 79-81.

Gupta, A.K., Berry, C.C. , Gupta, M. and Curtis, A.S.G. (2003) Receptor-mediated targeting of magnetic nanoparticles using insulin as a surface ligand to prevent endocytosis. IEEE Transactions on NanoBioscience, 2(4), pp. 255-261. (doi: 10.1109/TNB.2003.820279)

Berry, C.C. , Wells, S., Charles, S. and Curtis, A.S.G. (2003) Dextran and albumin derivatised iron oxide nanoparticles: influence on fibroblasts in vitro. Biomaterials, 24(25), pp. 4551-4557. (doi: 10.1016/S0142-9612(03)00237-0)

Dalby, M.J. , Riehle, M.O. , Johnstone, H.J.H., Affrossman, S. and Curtis, A.S.G. (2003) Nonadhesive nanotopography: fibroblast response to poly(n-butyl methacrylate)-poly(styrene) demixed surface features. Journal of Biomedical Materials Research Part A, 67A(3), pp. 1025-1032. (doi: 10.1002/jbm.a.10139)

Dalby, M.J. , Riehle, M.O. , Yarwood, S.J., Wilkinson, C.D.W. and Curtis, A.S.G. (2003) Nucleus alignment and cell signaling in fibroblasts: response to a micro-grooved topography. Experimental Cell Research, 284(2), pp. 272-280. (doi: 10.1016/S0014-4827(02)00053-8)

Barbucci, R., Pasqui, D., Wirsen, A., Affrossman, S., Curtis, A. and Tetta, C. (2003) Micro and nano-structured surfaces. Journal of Materials Science: Materials in Medicine, 14, pp. 721-725.

Berry, C.C. and Curtis, A.S.G. (2003) Functionalisation of magnetic nanoparticles for applications in biomedicine. Journal of Physics D: Applied Physics, 36(13), R198-R206. (doi: 10.1088/0022-3727/36/13/203)

Curtis, A.S.G. (2003) Biomedical aspects of magnetic nanoparticles. Europhysics News, 34(6), (doi: 10.1051/epn:2003602)

Dalby, M., Childs, S., Riehle, M.O. , Johnstone, H., Affrossman, S. and Curtis, A. (2003) Fibroblast reaction to island topography: changes in cytoskeleton and morphology with time. Biomaterials, 24, pp. 927-935.

Wilkinson, C.D.W., Thoms, S. , Macintyre, D., Curtis, A.S.G., Riehle, M. and Gadegaard, N. (2003) Nanofabrication of structures for cell engineering. Proceedings of the SPIE: The International Society for Optical Engineering, 5220, pp. 1-9. (doi: 10.1117/12.509749)

Curtis, A. (2002) Materials science: Breaking the neural code. Nature, 416(6878), pp. 274-275. (doi: 10.1038/416274a)

Berry, C.C. , Rudershausen, S., Teller, J. and Curtis, A.S.G. (2002) The influence of elastin-coated 520-nm- and 20-nm-diameter nanoparticles on human fibroblasts in vitro. IEEE Transactions on NanoBioscience, 1(3), pp. 105-109. (doi: 10.1109/TNB.2003.809467)

Dalby, M.J. , Riehle, M.O. , Johnstone, H., Affrossman, S. and Curtis, A. (2002) Polymer-demixed nanotopography: Control of fibroblast spreading and proliferation. Tissue Engineering, 8, pp. 1099-1108.

Dalby, M., Riehle, M.O. , Johnstone, H., Affrossman, S. and Curtis, A. (2002) In vitro reaction of endothelial cells to polymer demixed nanotopography. Biomaterials, 23, pp. 2945-2954.

Federle, W., Riehle, M. , Curtis, A. and Full, R. (2002) An integrative study of insect adhesion: Mechanics and wet adhesion of pretarsal pads in ants. Integrative and Comparative Biology, 42, pp. 1100-1106.

Sandison, M., Curtis, A. and Wilkinson, C. (2002) Effective extra-cellular recording from vertebrate neurons in culture using a new type of micro-electrode array. Journal of Neuroscience Methods, 114, pp. 63-71.

Wilkinson, C.D.W., Riehle, M. , Wood, M., Gallagher, J. and Curtis, A.S.G. (2002) The use of materials patterned on a nano- and micro-metric scale in cellular engineering. Materials Science and Engineering C: Biomimetic and Supramolecular Systems, 19(1-2), pp. 263-269. (doi: 10.1016/S0928-4931(01)00396-4)

Curtis, A. and Riehle, M. (2001) Tissue engineering: the biophysical background. Physics in Medicine and Biology, 46, R47-R65.

Curtis, A., Casey, B., Gallagher, J., Pasqui, D., Wood, M. and Wilkinson, C. (2001) Substratum nanotopography and the adhesion of biological cells. Are symmetry or regularity of nanotopography important? Biophysical Chemistry, 94, pp. 275-283.

Richards, R., Stiffanic, M., Owen, G., Riehle, M. , Gwynn, I. and Curtis, A. (2001) Immunogold labelling of fibroblast focal adhesion sites visualised in fixed material using scanning electron microscopy, and living, using internal reflection microscopy. Cell Biology International, 25, pp. 1237-1249. (doi: 10.1006/cbir.2001.0807)

Zhang, T., Morgan, H., Curtis, A. and Riehle, M. (2001) Measuring particle-substrate distance with surface plasmon resonance microscopy. Journal of Optics A: Pure and Applied Optics, 3, pp. 333-337.

Goodall, C. and Curtis, A. (1992) Modulation of adhesion of lymphocytes to murine brain endothelial cells in vitro: relation to class II major histocompatibility complex expression. Journal of Neuroimmunology, 37(1-2), pp. 9-22. (doi: 10.1016/0165-5728(92)90151-A)

Book Sections

Nikukar, H., Reid, S., Riehle, M.O. , Curtis, A.S.G. and Dalby, M.J. (2015) Control of mesenchymal stem-cell fate by engineering the nanoenvironment. In: Baharvand, H. and Aghdami, N. (eds.) Stem-Cell Nanoengineering. Wiley Blackwell: Hoboken, NJ, pp. 205-221. ISBN 9781118540619 (doi: 10.1002/9781118540640.ch12)

Beattie, A.J., Curtis, A.S.G., Wilkinson, C.D.W. and Riehle, M.O. (2009) Nanomaterials for neural interfaces: emerging new function and potential applications. In: Offenhausser, A. and Rinaldi, R. (eds.) Nanoelectronics - for Electronics, Biology, and Medicine. Series: Nanostructure Science and Technology. Springer: New York, USA, pp. 277-286. ISBN 9780387094598 (doi: 10.1007/978-0-387-09459-5)

Conference Proceedings

Morgan, H., Riehle, M. and Curtis, A.S.G. (2001) Surface plasmon resonance analysis of cell substrate interaction. In: 42nd Conference of the Society of Experimental Biology, Canterbury, UK,