Dr John Paul Leach

  • Professor of Clinical Neurology (Medicine)
  • Honorary Professor (School of Medicine, Dentistry & Nursing)

telephone: 01413308020
email: John.Leach@glasgow.ac.uk

Dept of Neurology, Medicine - Clinical Neuroscience, Southern General Hospital, Glasgow, G51 4tf

ORCID iDhttps://orcid.org/0000-0003-2086-9937

Publications

List by: Type | Date

Jump to: 2021 | 2020 | 2019 | 2017 | 2014 | 2010 | 2007 | 1997
Number of items: 20.

2021

Marson, A. et al. (2021) The SANAD II study of the effectiveness and cost-effectiveness of levetiracetam, zonisamide, or lamotrigine for newly diagnosed focal epilepsy: an open-label, non-inferiority, multicentre, phase 4, randomised controlled trial. Lancet, 397(10282), pp. 1363-1374. (doi: 10.1016/S0140-6736(21)00247-6) (PMID:33838757) (PMCID:PMC8047799)

Marson, A. et al. (2021) The SANAD II study of the effectiveness and cost-effectiveness of valproate versus levetiracetam for newly diagnosed generalised and unclassifiable epilepsy: an open-label, non-inferiority, multicentre, phase 4, randomised controlled trial. Lancet, 397(10282), pp. 1375-1386. (doi: 10.1016/S0140-6736(21)00246-4) (PMID:33838758) (PMCID:PMC8047813)

2020

Boyle, J.G., Colquhoun, I., Noonan, Z. , McDowall, S. , Walters, M.R. and Leach, J.P. (2020) Viva la VOSCE. BMC Medical Education, 20, 514. (doi: 10.1186/s12909-020-02444-3) (PMID:33334327) (PMCID:PMC7746425)

Mahmood, A., Abbasi, H. N., Ghouri, N. , Mohammed, R. and Leach, J. P. (2020) Managing epilepsy in Ramadan: guidance for healthcare providers and patients. Epilepsy and Behavior, 111, 107117. (doi: 10.1016/j.yebeh.2020.107117) (PMID:32599428)

Steinhoff, B. J., Christensen, J., Doherty, C. P., Majoie, M., De Backer, M., Hellot, S., Leunikava, I. and Leach, J. P. (2020) Effectiveness and tolerability of adjunctive brivaracetam in patients with focal seizures: second interim analysis of 6-month data from a prospective observational study in Europe. Epilepsy Research, 165, 106329. (doi: 10.1016/j.eplepsyres.2020.106329) (PMID:32623096)

Balbanova, S. et al. (2020) A study protocol for a pragmatic randomised controlled trial comparing the effectiveness and cost effectiveness of levetiracetam and zonisamide versus standard treatments for epilepsy: a comparison of Standard And New Antiepileptic Drugs (SANAD-II). BMJ Open, 10(8), (doi: 10.1136/bmjopen-2020- 040635) (PMID:32847927) (PMCID:PMC7451282)

Moss, L. , Henderson, M., Puxty, A., Shaw, M., Leach, J.P. , McPeake, J. and Quasim, T. (2020) Long‐term mortality of patients admitted to an intensive care unit with seizures: a population‐based study. Anaesthesia, 75(3), pp. 417-418. (doi: 10.1111/anae.14977) (PMID:32022911)

Kirby, J., Leach, V. M., Brockington, A., Patsalos, P., Reuber, M. and Leach, J. P. (2020) Drug withdrawal in the epilepsy monitoring unit – The patsalos table. Seizure, 75, pp. 75-81. (doi: 10.1016/j.seizure.2019.12.010) (PMID:31896534)

Noonan, Z. , Boyle, J. G., Pope, L., Ditchfield, C. , Leach, J. P. and McDowall, S. (2020) Quarantining the OSCE: reflections on the Glasgow experience. Clinical Teacher, 17(1), pp. 94-97. (doi: 10.1111/tct.12993) (PMID:30592158)

2019

Maguire, D. et al. (2019) Low serum magnesium and 1-year mortality in alcohol withdrawal syndrome. European Journal of Clinical Investigation, 49(9), e13152. (doi: 10.1111/eci.13152) (PMID:31216056)

Abbasi, H. and Leach, J. P. (2019) Refractory status epilepticus in adults admitted to ITU in Glasgow 1995-2013 a longitudinal audit highlighting the need for action for provoked and unprovoked status epilepticus. Seizure, 65, pp. 138-143. (doi: 10.1016/j.seizure.2019.01.011) (PMID:30690407)

2017

Salim, O. J., Davidson, A., Li, K., Leach, J. P. and Heath, C. (2017) Brainstem encephalitis and acute polyneuropathy associated with hepatitis E infection. BMJ Case Reports, 2017, 220799. (doi: 10.1136/bcr-2017-220799) (PMID:28899886)

Leach, J.P. et al. (2017) Epilepsy and pregnancy: for healthy pregnancies and happy outcomes. Suggestions for service improvements from the Multispecialty UK Epilepsy Mortality Group. Seizure, 50, pp. 67-72. (doi: 10.1016/j.seizure.2017.05.004) (PMID:28641176)

Nashef, L. and Leach, J. P. (2017) SUDEP, the aftermath: supporting the bereaved. Practical Neurology, 17(6), pp. 489-492. (doi: 10.1136/practneurol-2017-001729) (PMID:28972036)

2014

Leach, J. , Bagot, C. and Tait, R.C. (2014) Diagnosis and initial management of venous thrombosis; an audit of compliance with local and national guidelines. British Journal of Haematology, 165(s1), p. 43. (doi: 10.1111/bjh.12802) (PMID:24766253)

2010

Al Zweiri, M., Sills, G. J., Leach, J. P. , Brodie, M. J., Robertson, C., Watson, D. G. and Parkinson, J. A. (2010) Response to drug treatment in newly diagnosed epilepsy: A pilot study of H-1 NMR- and MS-based metabonomic analysis. Epilepsy Research, 88(2-3), pp. 189-195. (doi: 10.1016/j.eplepsyres.2009.11.005)

2007

Stephen, L. J., Sills, G. J., Leach, J. P. , Butler, E., Parker, P., Hitiris, N., Leach, V. M., Wilson, E. A. and Brodie, M. J. (2007) Sodium valproate versus lamotrigine: a randomised comparison of efficacy, tolerability and effects on circulating androgenic hormones in newly diagnosed epilepsy. Epilepsy Research, 75(2-3), pp. 122-129. (doi: 10.1016/j.eplepsyres.2007.04.009) (PMID:17553671)

1997

Leach, J. P. , Sills, G. J., Butler, E., Forrest, G., Thompson, G. G. and Brodie, M. J. (1997) Neurochemical actions of gabapentin in mouse brain. Epilepsy Research, 27(3), pp. 175-180. (doi: 10.1016/S0920-1211(97)01034-6) (PMID:9237051)

Leach, J. P. , Sills, G. J., Butler, E., Forrest, G., Thompson, G. G. and Brodie, M. J. (1997) Neurochemical actions of the desglycinyl metabolite of remacemide hydrochloride (ARL 12495AA) in mouse brain. British Journal of Pharmacology, 121(5), pp. 923-926. (doi: 10.1038/sj.bjp.0701219) (PMID:9222548) (PMCID:PMC1564774)

Sills, G. J., Leach, J. P. , Fraser, C. M., Forrest, G., Patsalos, P. N. and Brodie, M. J. (1997) Neurochemical studies with the novel anticonvulsant levetiracetam in mouse brain. European Journal of Pharmacology, 325(1), pp. 35-40. (doi: 10.1016/S0014-2999(97)00105-2) (PMID:9151936)

This list was generated on Thu Jun 24 11:56:20 2021 BST.
Jump to: Articles
Number of items: 20.

Articles

Marson, A. et al. (2021) The SANAD II study of the effectiveness and cost-effectiveness of levetiracetam, zonisamide, or lamotrigine for newly diagnosed focal epilepsy: an open-label, non-inferiority, multicentre, phase 4, randomised controlled trial. Lancet, 397(10282), pp. 1363-1374. (doi: 10.1016/S0140-6736(21)00247-6) (PMID:33838757) (PMCID:PMC8047799)

Marson, A. et al. (2021) The SANAD II study of the effectiveness and cost-effectiveness of valproate versus levetiracetam for newly diagnosed generalised and unclassifiable epilepsy: an open-label, non-inferiority, multicentre, phase 4, randomised controlled trial. Lancet, 397(10282), pp. 1375-1386. (doi: 10.1016/S0140-6736(21)00246-4) (PMID:33838758) (PMCID:PMC8047813)

Boyle, J.G., Colquhoun, I., Noonan, Z. , McDowall, S. , Walters, M.R. and Leach, J.P. (2020) Viva la VOSCE. BMC Medical Education, 20, 514. (doi: 10.1186/s12909-020-02444-3) (PMID:33334327) (PMCID:PMC7746425)

Mahmood, A., Abbasi, H. N., Ghouri, N. , Mohammed, R. and Leach, J. P. (2020) Managing epilepsy in Ramadan: guidance for healthcare providers and patients. Epilepsy and Behavior, 111, 107117. (doi: 10.1016/j.yebeh.2020.107117) (PMID:32599428)

Steinhoff, B. J., Christensen, J., Doherty, C. P., Majoie, M., De Backer, M., Hellot, S., Leunikava, I. and Leach, J. P. (2020) Effectiveness and tolerability of adjunctive brivaracetam in patients with focal seizures: second interim analysis of 6-month data from a prospective observational study in Europe. Epilepsy Research, 165, 106329. (doi: 10.1016/j.eplepsyres.2020.106329) (PMID:32623096)

Balbanova, S. et al. (2020) A study protocol for a pragmatic randomised controlled trial comparing the effectiveness and cost effectiveness of levetiracetam and zonisamide versus standard treatments for epilepsy: a comparison of Standard And New Antiepileptic Drugs (SANAD-II). BMJ Open, 10(8), (doi: 10.1136/bmjopen-2020- 040635) (PMID:32847927) (PMCID:PMC7451282)

Moss, L. , Henderson, M., Puxty, A., Shaw, M., Leach, J.P. , McPeake, J. and Quasim, T. (2020) Long‐term mortality of patients admitted to an intensive care unit with seizures: a population‐based study. Anaesthesia, 75(3), pp. 417-418. (doi: 10.1111/anae.14977) (PMID:32022911)

Kirby, J., Leach, V. M., Brockington, A., Patsalos, P., Reuber, M. and Leach, J. P. (2020) Drug withdrawal in the epilepsy monitoring unit – The patsalos table. Seizure, 75, pp. 75-81. (doi: 10.1016/j.seizure.2019.12.010) (PMID:31896534)

Noonan, Z. , Boyle, J. G., Pope, L., Ditchfield, C. , Leach, J. P. and McDowall, S. (2020) Quarantining the OSCE: reflections on the Glasgow experience. Clinical Teacher, 17(1), pp. 94-97. (doi: 10.1111/tct.12993) (PMID:30592158)

Maguire, D. et al. (2019) Low serum magnesium and 1-year mortality in alcohol withdrawal syndrome. European Journal of Clinical Investigation, 49(9), e13152. (doi: 10.1111/eci.13152) (PMID:31216056)

Abbasi, H. and Leach, J. P. (2019) Refractory status epilepticus in adults admitted to ITU in Glasgow 1995-2013 a longitudinal audit highlighting the need for action for provoked and unprovoked status epilepticus. Seizure, 65, pp. 138-143. (doi: 10.1016/j.seizure.2019.01.011) (PMID:30690407)

Salim, O. J., Davidson, A., Li, K., Leach, J. P. and Heath, C. (2017) Brainstem encephalitis and acute polyneuropathy associated with hepatitis E infection. BMJ Case Reports, 2017, 220799. (doi: 10.1136/bcr-2017-220799) (PMID:28899886)

Leach, J.P. et al. (2017) Epilepsy and pregnancy: for healthy pregnancies and happy outcomes. Suggestions for service improvements from the Multispecialty UK Epilepsy Mortality Group. Seizure, 50, pp. 67-72. (doi: 10.1016/j.seizure.2017.05.004) (PMID:28641176)

Nashef, L. and Leach, J. P. (2017) SUDEP, the aftermath: supporting the bereaved. Practical Neurology, 17(6), pp. 489-492. (doi: 10.1136/practneurol-2017-001729) (PMID:28972036)

Leach, J. , Bagot, C. and Tait, R.C. (2014) Diagnosis and initial management of venous thrombosis; an audit of compliance with local and national guidelines. British Journal of Haematology, 165(s1), p. 43. (doi: 10.1111/bjh.12802) (PMID:24766253)

Al Zweiri, M., Sills, G. J., Leach, J. P. , Brodie, M. J., Robertson, C., Watson, D. G. and Parkinson, J. A. (2010) Response to drug treatment in newly diagnosed epilepsy: A pilot study of H-1 NMR- and MS-based metabonomic analysis. Epilepsy Research, 88(2-3), pp. 189-195. (doi: 10.1016/j.eplepsyres.2009.11.005)

Stephen, L. J., Sills, G. J., Leach, J. P. , Butler, E., Parker, P., Hitiris, N., Leach, V. M., Wilson, E. A. and Brodie, M. J. (2007) Sodium valproate versus lamotrigine: a randomised comparison of efficacy, tolerability and effects on circulating androgenic hormones in newly diagnosed epilepsy. Epilepsy Research, 75(2-3), pp. 122-129. (doi: 10.1016/j.eplepsyres.2007.04.009) (PMID:17553671)

Leach, J. P. , Sills, G. J., Butler, E., Forrest, G., Thompson, G. G. and Brodie, M. J. (1997) Neurochemical actions of gabapentin in mouse brain. Epilepsy Research, 27(3), pp. 175-180. (doi: 10.1016/S0920-1211(97)01034-6) (PMID:9237051)

Leach, J. P. , Sills, G. J., Butler, E., Forrest, G., Thompson, G. G. and Brodie, M. J. (1997) Neurochemical actions of the desglycinyl metabolite of remacemide hydrochloride (ARL 12495AA) in mouse brain. British Journal of Pharmacology, 121(5), pp. 923-926. (doi: 10.1038/sj.bjp.0701219) (PMID:9222548) (PMCID:PMC1564774)

Sills, G. J., Leach, J. P. , Fraser, C. M., Forrest, G., Patsalos, P. N. and Brodie, M. J. (1997) Neurochemical studies with the novel anticonvulsant levetiracetam in mouse brain. European Journal of Pharmacology, 325(1), pp. 35-40. (doi: 10.1016/S0014-2999(97)00105-2) (PMID:9151936)

This list was generated on Thu Jun 24 11:56:20 2021 BST.

Grants

Grants and Awards listed are those received whilst working with the University of Glasgow.

  • Evaluating Fairness In Assessment At Four Scottish Medical Schools Pat MacLennan, SMERC Administrator, Email: pmaclennan@abdn.ac.uk

    2019 - 2019