Dr Craig Daly

  • Senior Lecturer (Life Sciences Human Life Sciences)

Research interests

I have been studying the cardiovascular system for over 30 years. My particular interest is in the autonomic (nerve-mediated) control of arteries and veins and, in particular, the interactions between the various cells of the vascular wall. 

Recent work has focused on the role of fat which surrounds most of the blood vessels of the body. This perivascular fat is thought to contribute to the relationship between hypertension, obesity and diabetes.

As a course coordinator (since 2004) I have also become interested in the use of 3D animation for teaching physiology, pharmacology and autonomic neuroscience. My novel approach is to combine 3D microscopy with Pixar-style animation software. 

The resulting animations are anatomically correct to within 0.1mm and are therefore not ‘artists impressions’ (unlike most physiology-based animations you will find on You-Tube).  This interest has now developed into the use of Virtual Reality for teaching and research purposes.

 

Find out more about my research


Publications

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Number of items: 131.

2019

Alganga, H. S. F., Almabrouk, T. A.M. , Katwan, O. J., Daly, C. J. , Pyne, S., Pyne, N. J. and Kennedy, S. (2019) Short periods of hypoxia upregulate sphingosine kinase 1 and increase vasodilation of arteries to Sphingosine 1-phosphate via S1P3. Journal of Pharmacology and Experimental Therapeutics, 371(1), pp. 63-74. (doi:10.1124/jpet.119.257931) (PMID:31371480)

Garcia Cordoba, C. and Daly, C. J. (2019) The organisation of vascular smooth muscle cells; a quantitative Fast Fourier Transform (FFT) based assessment. Translational Research in Anatomy, 16, 100047. (doi:10.1016/j.tria.2019.100047)

Daly, C. J. (2019) From confocal microscope to virtual reality and computer games; technical and educational considerations. Infocus Magazine, 54, pp. 51-59.

Daly, C. J. (2019) Examining vascular structure and function using confocal microscopy and 3D imaging techniques. In: Rea, P. M. (ed.) Biomedical Visualisation. Series: Advances in experimental medicine and biology (1120). Springer: Cham, pp. 97-106. ISBN 9783030060695 (doi:10.1007/978-3-030-06070-1_8)

Daly, C. J. (2019) Imaging the vascular wall: from microscope to virtual reality. In: Touyz, R. M. and Delles, C. (eds.) Textbook of Vascular Medicine. Springer: Cham, pp. 59-66. ISBN 9783030164805 (doi:10.1007/978-3-030-16481-2_6)

2018

Daly, C. J. (2018) The future of education? Using 3D animation and virtual reality in teaching physiology. Physiology News, 111(Summer), p. 43.

2017

Nguyen, L. P. et al. (2017) β2-Adrenoceptor signaling in airway epithelial cells promotes eosinophilic inflammation, mucous metaplasia, and airway contractility. Proceedings of the National Academy of Sciences of the United States of America, 114(43), E9163-E9171. (doi:10.1073/pnas.1710196114) (PMID:29073113)

Patil, K. C. and Daly, C. J. (2017) Nanotechnology-based α1-adrenoceptor/gpr55 biomarker assay: molecular prognostic test for aggressive prostate cancer on the horizon? Socrates Almanac, 2017(8/2), pp. 20-22.

Abu Bakar, H., Dunn, W. R., Daly, C. and Ralevic, V. (2017) Sensory innervation of perivascular adipose tissue: a crucial role in artery vasodilatation and leptin release. Cardiovascular Research, 113(8), pp. 962-972. (doi:10.1093/cvr/cvx062) (PMID:28371926)

2016

Daly, C.J. , Bulloch, J.M., Ma, M. and Aidulis, D. (2016) A comparison of animated versus static images in an instructional multimedia presentation. Advances in Physiology Education, 40(2), pp. 201-205. (doi:10.1152/advan.00053.2015) (PMID:27105738)

2015

Patil, K. C., McPherson, L. and Daly, C. J. (2015) Co-localization of alpha1-adrenoceptors and GPR55: a novel prostate cancer paradigm? Pharmacology and Pharmacy, 6(4), pp. 212-220. (doi:10.4236/pp.2015.64023)

2014

Bulloch, J. M. and Daly, C. J. (2014) Autonomic nerves and perivascular fat: interactive mechanisms. Pharmacology and Therapeutics, 143(1), pp. 61-73. (doi:10.1016/j.pharmthera.2014.02.005)

Shafaroudi, M. M. and Daly, C. J. (2014) Endothelial vasodilator angiotensin receptors are changing in mice with ageing. Research in Molecular Medicine, 2(1), pp. 26-34. (doi:10.18869/acadpub.rmm.2.1.26)

2012

Daly, C. J. , Parmryd, I. and McGrath, J. C. (2012) Visualization and analysis of vascular receptors using confocal laser scanning microscopy and fluorescent ligands. Methods in Molecular Biology, 897, pp. 95-107. (doi:10.1007/978-1-61779-909-9_5)

2011

Daly, C.J. and McGrath, J.C. (2011) Previously unsuspected widespread cellular and tissue distribution of β-adrenoceptors and its relevance to drug action. Trends in Pharmacological Sciences, 32(4), pp. 219-226. (doi:10.1016/j.tips.2011.02.008)

2010

Daly, C.J., Ross, R.A., Whyte, J., Henstridge, C.M., Irving, A.J. and McGrath, J.C. (2010) Fluorescent ligand binding reveals heterogeneous distribution of adrenoceptors and ‘cannabinoid-like’ receptors in small arteries. British Journal of Pharmacology, 159(4), pp. 787-796. (doi:10.1111/j.1476-5381.2009.00608.x)

Davenport, A.P. and Daly, C.J. (2010) Imaging in pharmacology: editorial. British Journal of Pharmacology, 159(4), pp. 735-737. (doi:10.1111/j.1476-5381.2010.00685.x)

Clark, N.D.L. and Daly, C.J. (2010) Using confocal laser scanning microscopy to image trichome inclusions in amber. Journal of Paleontological Techniques, 8, pp. 1-7.

2008

McGrath, J.C. , Methven, L., Hamill, C., Macmillan, J., Arribas, S., Briones, A., Vila, E. and Daly, C.J. (2008) Which vascular cells have adrenoceptors? Journal of Vascular Research, 45(Supple), 39--. (doi:10.1159/000113929)

Methven, L., Hamill, C., MacMillan, J., Daly, C.J. , McGrath, J.C. and Simpson, P.C. (2008) Functional responses in the a1AB- adrenoceptor knockout mouse indicate that the a1D- adrenoceptor has a role in the contraction of small mesenteric arteries. Journal of Vascular Research, 45(Supple), 45--. (doi:10.1159/000113929)

Daly, C.J. , Wallace, G., White, K., Henstridge, C., Irving, A. and McGrath, J.C. (2008) Visualisation of Vascular Cannabinoid Receptors and their Potential Interaction with alpha1-adrenergic Receptors. In: Vascular and Smooth Muscle Physiology. Themed Meeting of the Physiological Society, King's College, London, December 2008,

Hamill, C., Gonzalez, J.M., Methven, L., Daly, C.J. and McGrath, J.C. (2008) Approaches to visualising myoendothelial connections using laser scanning confocal microscopy. Journal of Vascular Research, 45(Supple), p. 8. (doi:10.1159/000113929)

Shafaroudi, M.M., Daly, C.J. and McGrath, J.C. (2008) Multiple action sites of alpha2-AR agonist (UK14304) on different adrenoreceptors in mice aorta. Journal of Damghan University of Basic Sciences, 1(3), pp. 111-122.

White, K., McGrath, J.C. and Daly, C.J. (2008) Selective delivery of dsRNA to resistance artery endothelial cells. Journal of Vascular Research, 45(Supple), p. 7. (doi:10.1159/000113929)

2007

Arribas, S.M., Daly, C.J. , Gonzalez, M.C. and McGrath, J. (2007) Imaging the vascular wall using confocal microscopy. Journal of Physiology, 584(1), pp. 5-9. (doi:10.1113/jphysiol.2007.137786)

Morton, J.S., Daly, C.J. , Jackson, V.M. and McGrath, J.C. (2007) α1A-Adrenoceptors mediate contractions to phenylephrine in rabbit penile arteries. British Journal of Pharmacology, 150(1), pp. 112-120.

2006

McGrath, J. C. and Daly, C. J. (2006) Use of fluorescent ligands and receptors to visualize adrenergic receptors. In: Perez, D. M. (ed.) The Adrenergic Receptors: In the 21st Century. Series: The receptors, III. Humana Press, pp. 151-172. ISBN 9781588294234 (doi:10.1385/1-59259-931-1:151)

2005

Briones, A. M., Daly, C. J. , Jimenez-Altayo, F., Martinez-Revelles, S., Gonzalez, J. M., McGrath, J. C. and Vila, E. (2005) Direct demonstration of β1- and evidence against β2- and β3-adrenoceptors, in smooth muscle cells of rat small mesenteric arteries. British Journal of Pharmacology, 146(5), pp. 679-691. (doi:10.1038/sj.bjp.0706369)

Briones, A. M., Daly, C. J. , Jimenez-Altayo, F., Martinez-Revelles, S., Gonzalez, J. M., McGrath, J. C. and Vila, E. (2005) Direct demonstration of β1- and evidence against β2- and β3-adrenoceptors, in smooth muscle cells of rat small mesenteric arteries. British Journal of Pharmacology, 146(5), pp. 679-691. (doi:10.1038/sj.bjp.0706369)

Daly, C. J. , McGrath, I. , Townsend, S. and Berkowitz, D. E. (2005) The role of the 1B-adrenergic receptor in vascular structure and function. Hypertension, 45(6), e20-e21. (doi:10.1161/01.HYP.0000167153.83102.15)

Gonzalez, J.M., Briones, A.M., Starcher, B., Conde, M.V., Somoza, B., Daly, C. , Vila, E., McGrath, I., Gonzalez, M.C. and Arribas, S.M. (2005) Influence of elastin on rat small artery mechanical properties. Experimental Physiology, 90, pp. 463-468. (doi:10.1113/expphysiol.2005.030056)

Miquel, M., Ali, Z., Segura, V., D'Ocon, M.P., Mcgrath, J. and Daly, C. (2005) 3D image analysis of fluorescent drug binding. Molecular Imaging, 4(1), pp. 1-13.

Morton, J.S., Daly, C.J. , McGrath, J.C. and Jackson, V.M. (2005) Development of an in vitro method to study vaginal arteries using myography. In: University of Newcastle Winter Meeting, Newcastle, UK, 2005,

2004

Morton, J.S., Daly, C.J. , Jackson, V.M., Van Der Graff, P.H. and McGrath, J. (2004) Development of an in vitro method to study penile resistance vessels using myography. Proceedings of the British Pharmacological Society, 11(4), 038P.

2003

Briones, A.M., Gonzalez, J.M., Somoza, B., Giraldo, J., Daly, C.J. , Vila, E., Gonzalez, M.C., McGrath, J.C. and Arribas, S.M. (2003) Role of elastin in spontaneously hypertensive rat small mesenteric artery remodelling. Journal of Physiology, 552, pp. 185-195. (doi:10.1113/jphysiol.2003.046904)

McGrath, J.C. and Daly, C.J. (2003) Do fluorescent drugs show you more than you wanted to know? British Journal of Pharmacology, 139(2), pp. 187-189. (doi:10.1038/sj.bjp.0705288)

Coats, P., Jarajapu, Y., Hillier, C., McGrath, J. and Daly, C. (2003) The use of fluorescent nuclear dyes and laser scanning confocal microscopy to study the cellular aspects of arterial remodelling in human subjects with critical limb ischaemia. Experimental Physiology, 88, pp. 547-554.

Cockshott, W.P., Tao, Y.G., Gao, G., Balch, P., Briones, A.M. and Daly, C. (2003) Confocal microscopic image sequence compression using vector quantization and three-dimensional pyramid. Scanning, 25, pp. 247-256.

Hamid, S.A., Daly, C. and Campbell, S. (2003) Visualization of live endothelial cells ex vivo and in vitro. Microvascular Research, 66, pp. 159-163. (doi:10.1016/S0026-2862(03)00054-2)

2002

Ali, Z., McGrath, J.C. and Daly, C.J. (2002) Characterisation of the contractile alpha1- adrenoceptor response in the mouse thoracic aorta. British Journal of Pharmacology, 137(Suppl.), 92P.

Brahmadevara, N., Macdonald, A., McGrath, J. and Daly, C. (2002) Measurement of cellular and tissue distribution of beta-adrenoceptors in rat thoracic aorta using BODIPY-CGP 12177. British Journal of Pharmacology, 137(Suppl.), 93P.

Daly, C. et al. (2002) Analysing the 3D structure of blood vessels using confocal microscopy. Microscopy and Analysis, 92, pp. 5-8.

Daly, C. , Pediani, J. , Mackenzie, J.F. and McGrath, J. (2002) Visualising agonist and antagonist interactions: the value of fluorescent ligands. Pharmacologist, 44(2), A73.

Jarajapu, Y.P.R., Macdonald, A., Hillier, C., McGrath, J. , Mackenzie, J.F. and Daly, C. (2002) Quantitative imaging of QAPB-associated fluorescence in smooth muscle cells from human skeletal muscle resistance arteries. British Journal of Pharmacology, 135(Suppl.), 303P.

McBride, M., Daly, C. and McGrath, J. (2002) Alpha1 and alpha2-adrenoceptors mediating resistance artery contraction as revealed by receptor “knockouts”. Pharmacologist, 44(2), A79.

McBride, M., Daly, C. and McGrath, J. (2002) Contractile responses to UK 14304 in the mouse tail artery differ when the drug is administered cumulatively or non-cumulatively. In: 7th Annual Meeting of the European Council for Blood Pressure and Cardiovascular Research (ECCR), Seeheim, Germany, 11-13 Oct 2002,

McBride, M., Daly, C. and McGrath, J. (2002) Contractile responses to UK14304 are inhibited by low concentrations of rauwolscine but are unaffected by prazosin in mouse tail artery. British Journal of Pharmacology, 137(Suppl.), 91P.

McBride, M., Daly, C. and McGrath, J. (2002) Tail arteries from D79N mice show reduced responses to UK14304 compared with wild type. British Journal of Pharmacology, 135(Suppl.), 304P.

McGrath, J. and Daly, C. (2002) Fluorescence technologies for the study of receptors. Pharmacologist, 44(2), A73.

Shafaroudi, M., Daly, C. and McGrath, J. (2002) Analysis of alpha2-adrenoceptor- and angiotensin-mediated responses in mouse aorta. Pharmacologist, 44(2), A79.

2000

Shang, C., McGrath, J. , Daly, C. and Barker, J. (2000) Modelling and classification of vascular smooth muscle cell images. Electronics Letters, 36(18), pp. 1532-1533. (doi:10.1049/el:20001106)

Mackenzie, J. F., Daly, C. J., Pediani, J. D. and McGrath, J. C. (2000) Quantitative imaging in live human cells reveals intracellular alpha(1)-adrenoceptor ligand-binding sites. Journal of Pharmacology and Experimental Therapeutics, 294(2), pp. 434-443.

Pediani, J. D. , Mackenzie, J. F., Heeley, R. P., Daly, C. J. and McGrath, J. C. (2000) Single-cell recombinant pharmacology: bovine α1a-adrenoceptors in rat-1 fibroblasts release intracellular Ca2+, display subtype-characteristic agonism and antagonism, and exhibit an antagonist-reversible inverse concentration-response phase. Journal of Pharmacology and Experimental Therapeutics, 293(3), pp. 887-895.

Daly, C.J. , Vila, E., Arribas, S.M., Pagakis, S., Thebault, B., Maddison, J., Pederson, J. and McGrath, J.C. (2000) 3-dimensional analysis of vascular structure, function & receptor distribution using confocal laser scanning microscopy. In: 10th Porto Meeting on Adrenergic Mechanisms, Porto, Portugal, 25-27 Sep 2000,

Granitsioti, P., Daly, C. , Kirk, D. and McGrath, J. (2000) Physiology of the human vas deferens; Clinical importance. In: 10th Porto Meeting on Adrenergic Mechanisms, Porto, Portugal, 25-27 Sept 2000,

Mackenzie, J.F., Pediani, J. , Daly, C. , Deighan, C. and McGrath, J. (2000) Fluorescent ligand binding to alpha1-adrenoceptors in murine hepatocytes. In: 10th Porto Meeting on Adrenergic Mechanisms, Porto, Portugal, 25-27 Sept 2000, P2.

Shang, C., Daly, C. , McGrath, J. and Barker, J. (2000) Neural network based classification of cell images via estimation of fractal dimensions. In: International Conference on Artificial Neural Networks in Medicine and Biology, Goteburg, Sweden, 13-16 May 2000, pp. 111-116. (doi:10.1007/978-1-4471-0513-8_15)

1999

Shaw, A. M., Bunton, D. C., Fisher, A., McGrath, J. C. , Montgomery, I., Daly, C. and MacDonald, A. (1999) V-shaped cushion at the origin of bovine pulmonary supernumerary arteries: structure and putative function. Journal of Applied Physiology, 87(6), pp. 2348-2356.

McGrath, J.C. , Mackenzie, J.F. and Daly, C. J. (1999) Pharmacological implications of cellular localization of α1-adrenoceptors in native smooth muscle cells. Journal of Autonomic Pharmacology, 19(6), pp. 303-310. (doi:10.1111/j.1365-2680.1999.tb00002.x)

Mackenzie, J.F., Daly, C.J. , Luo, D. and McGrath, J.C. (1999) Cellular localisation of alpha1 -adrenoceptors in human primary smooth muscle cells derived from the prostate of patients with benign prostatic hypertrophy. European Urology, 36(S1), p. 115. (doi:10.1159/000052331)

McGrath, J.C. , Nagadeh, M.A., Pediani, J.D. , Mackenzie, J.F. and Daly, C.J. (1999) Importance of agonists in α-adrenoceptor classification and localisation of α1-adrenoceptors in human prostate. European Urology, 36(S1), pp. 80-88. (doi:10.1159/000052326)

McGrath, J.C. , Mackenzie, J.F. and Daly, C.J. (1999) Sub-cellular localisation of alpha1-adrenoceptors in live cells and tissues. In: British Pharmacological Societ Joint Spring Meeting with Portuguese Pharmacological Society, Porto, Portugal, 8-9 Apr 1999, 133P.

1998

Luo, D., Barker, J., McGrath, J.C. and Daly, C.J. (1998) Iterative multilevel thresholding and splitting for 3D segmentation of live cell nuclei using laser scanning confocal microscopy. Journal of Computer-Assisted Microscopy, 10(4), pp. 151-162. (doi:10.1023/A:1023482003483)

Daly, C.J. , Milligan, C.M., Milligan, G. , Mackenzie, J.F. and McGrath, J.C. (1998) Cellular localization and pharmacological characterization of functioning alpha-1 adrenoceptors by fluorescent ligand binding and image analysis reveals identical binding properties of clustered and diffuse populations of receptors. Journal of Pharmacology and Experimental Therapeutics, 286(2), pp. 984-990.

Daly, C.J. , Milligan, C.M., Milligan, G. , Mackenzie, J.F. and McGrath, J.C. (1998) Cellular localization and pharmacological characterization of functioning alpha-1 adrenoceptors by fluorescent ligand binding and image analysis reveals identical binding properties of clustered and diffuse populations of receptors. Journal of Pharmacology and Experimental Therapeutics, 286(2), pp. 984-990.

Daly, C.J. , Cotecchia, S. and McGrath, J.C. (1998) Low frequency electrical field stimulation elicits responses in segments of mouse tail artery which are slower in alpha1B-knockout mice than in control mice. Naunyn-Schmiedeberg's Archives of Pharmacology, 358(S2), P6.40.

Giummelly, P., Colas, T., Atkinson, J., Robert, A., Daly, C.J. , Luo, D. and McGrath, J.C. (1998) Fluorescence of the medial aortic elastic lamella in elastocalcinotic rats. Naunyn-Schmiedeberg's Archives of Pharmacology, 358(S1), P37.36.

Luo, D., Daly, C.J. , Mackenzie, J.F., McGrory, S.P., Robert, A. and McGrath, J.C. (1998) 3D remodelling of alpha1-adrenoceptors in live cells using a fluorescent ligand, QAPB and confocal laser scanning microscopy. Naunyn-Schmiedeberg's Archives of Pharmacology, 358(S2), P6.44.

Mackenzie, J.F., Daly, C.D. and McGrath, J.C. (1998) Comparison and validation of human a1-adrenoceptor binding characteristics on live, whole cells using radioligand binding and confocal laser scanning microscopic techniques. Naunyn-Schmiedeberg's Archives of Pharmacology, 358(S2), P6.45.

Pediani, J. , Mackenzie, J.F., Daly, C. and McGrath, J. (1998) Comparison of functional and binding pharmacological properties of the cloned bovine a 1a-adrenoceptor (a 1a-AR) stably expressed in rat-1 fibroblasts. Naunyn-Schmiedeberg's Archives of Pharmacology, 358(S2), P6.47.

Robert, A., Daly, C.J. , Luo, D., Montgomery, I. and McGrath, J.C. (1998) Decrease of the medial carotid elastin componentin rabbit ligated coronary heart failure model. Naunyn-Schmiedeberg's Archives of Pharmacology, 358(S2), P57.22.

Robert, A., Daly, C.J. and McGrath, J.C. (1998) Decrease of in vitro carotid compliance in rabbit heart failure model. In: Heart Failure Update, Glasgow, UK, 1998, p. 8.

1997

Daly, C.J., , de la Rue, S.A., Luo, D. and McGrath, J.C. (1997) 3D-distribution of a-adrenoceptors in blood vessel lack of staining on endothelial cells. Journal of Vascular Research, 34(Sup 1), p. 34. (doi:10.1159/000317489)

1996

McGrath, J. C. , Arribas, S. and Daly, C. J. (1996) Fluorescent ligands for the study of receptors. Trends in Pharmacological Sciences, 17(11), pp. 393-399. (doi:10.1016/S0165-6147(96)40004-9)

Arribas, S. M., Gordon, J. F., Daly, C. J. , Dominiczak, A. F. and McGrath, J. C. (1996) Confocal microscopic characterization of a lesion in a cerebral vessel of the stroke-prone spontaneously hypertensive rat. Stroke, 27(6), pp. 1118-1123. (doi:10.1161/01.STR.27.6.1118)

McGrath, J. and Daly, C. (1996) Functional antagonism and receptor-induced fluorescence in rat anococcygeus. FASEB Journal, 10(3), p. 2448.

1995

McGrath, J.C. , Arribas, S., Daly, C.J. and Gordon, J.F. (1995) Confocal microscopy for structure and realtime pharmacology in blood vessels. Journal of Human Hypertension, 9(8), pp. 645-647.

McGrath, J.C. et al. (1995) The relationship between the adrenoceptor and nonadrenoceptor-mediated effects of imidazoline- and imidazole-containing compounds. Annals of the New York Academy of Sciences, 763(1), pp. 591-605. (doi:10.1111/j.1749-6632.1995.tb32454.x)

Shakur, Y., Wilson, M., Pooley, L., Lobban, M., Griffiths, S.L., Campbell, A.M., Beattie, J., Daly, C. and Houslay, M.D. (1995) Identification and characterization of the type-IVA cyclic AMP-specific phosphodiesterase RD1 as a membrane-bound protein expressed in cerebellum. Biochemical Journal, 306, pp. 801-809.

Arribas, S., Daly, C. , Dominiczak, A. and McGrath, J. (1995) Reduced vasodilator responses to noradrenaline correlates with decreased density of -adrenoceptor flurophore binding in the basilar artery from old WKY rats. Methods and Finding in Experimental and Clinical Pharmacology, 17, CO30.

Arribas, S.M., Gordon, J.F., Daly, C.J. , Davidson, A., Dominiczak, A. and McGrath, J.C. (1995) Structural and functional alterations in the basilar artery from stroke prone spontaneously hypertensive rats. In: 7th European Meeting on Hypertension, Milan, Italy, 9-12 Jun 1995, p. 12.

McGrath, J. and Daly, C. (1995) Viewing adrenoceptors; past, present, and future; commentary and a new technique. Pharmacology Communications, 1(6), pp. 269-279.

1994

Arribas, S., Gordon, J.F., Daly, C. , Davidson, A., Dominiczak, A. and McGrath, J.C. (1994) Vascular smooth muscle rearrangement and impaired contractions in basilar artery of the stroke-prone spontaneously hypertensive rat. Journal of Hypertension, 12(11), p. 1319.

Arriba, S.M., Daly, C.J. , Gordon, J.F. and McGrath, J.C. (1994) Confocal myography: applications for the study of resistance arteries. In: Halpern, W., Bevan, J.A., Brayden, J., Dustan, H. and Nelson, M. (eds.) The Resistance Arteries: Integration of the Regulatory Pathways. Series: Experimental biology and medicine (26). Humana Press: New York, NY, pp. 259-264. ISBN 9781617370083

Daly, C.J. , Gordon, J.F. and McGrath, J.C. (1994) The use of confocal microscopy for the study of resistance artery structure and function. Journal of Vascular Research, 31(Sup 1), p. 10. (doi:10.1159/000159068)

Macmillan, J.M., Daly, C.J. and McGrath, J.C. (1994) The innervation and alpha-adrenoceptor profile of rabbit isolated dorsal cutaneous and sub-cutaneous resistance arteries. Journal of Vascular Research, 31(Sup 1), p. 30. (doi:10.1159/000317452)

1993

Daly, C.J. , Gordon, J.F. and McGrath, J.C. (1993) Dimensional analysis of smooth muscle cell reactivity within the rat resistance artery using confocal microscopy. In: XXXII Congress of the International Union of Physiological Sciences, Glasgow, UK, 1-6 Aug 1993,

Daly, C.J. , Gordon, J.F. and McGrath, J.C. (1993) Observation of vasodilatation in small arteries with confocal microscopy. In: XXXII Congress of the International Union of Physiological Sciences, Glasgow, UK, 1-6 Aug 1993,

Gordon, J.F., Daly, C.J. and McGrath, J.C. (1993) Analysis of rat resistance artery structure in pressurised vessels using confocal microscopy. In: XXXII Congress of the International Union of Physiological Sciences, Glasgow, UK, 1-6 Aug 1993,

Moss, V.A., Gordon, J.F. and Daly, C.J. (1993) Software for the automated determination of 3-D coordinates of cell nuclei labelled with fluorescent dyes imaged using confocal microscopy. In: XXXII Congress of the International Union of Physiological Sciences, Glasgow, UK, 1-6 Aug 1993,

1992

Gordon, J.F., Baird, M., Daly, C.J. and McGrath, J.C. (1992) Endogenous nitric oxide modulates sympathetic neuroeffector transmission in the isolated rabbit lateral saphenous vein. Journal of Cardiovascular Pharmacology, 20(Sup 12), S68-S71.

MacDonald, A., Daly, C.J. , Bulloch, J.M. and McGrath, J.C. (1992) Contributions of α1-adrenoceptors, α2-adrenoceptors and P2x-purinoceptors to neurotransmission in several rabbit isolated blood vessels: role of neuronal uptake and autofeedback. British Journal of Pharmacology, 105(2), pp. 347-354. (doi:10.1111/j.1476-5381.1992.tb14257.x)

Clinch, N.F., Daly, C.J. , Gordon, J.F., Moss, V.A. and Spurway, N.C. (1992) Wide-field volume visualisation of thick microscope sections by computed nearest neighbour deconvolutions. Journal of Physiology, 452, 3P.

Daly, C.J. , Gordon, J.F. and McGrath, J.C. (1992) Endogenous nitric oxide modulates sympathetic neuroeffector transmission in the rabbit isolated lateral saphenous vein. Journal of Vascular Research, 29(2), p. 99. (doi:10.1159/000317442)

Daly, C.J. , Gordon, J.F. and McGrath, J.C. (1992) The use of fluorescent nuclear dyes for the study of blood vessel structure and function: novel applications of existing techniques. Journal of Vascular Research, 29(1), pp. 41-48. (doi:10.1159/000158930)

Daly, C.J. , MacLean, M.R. and McGrath, J.C. (1992) Electrical field stimulation of rabbit isolated cutaneous and pulmonary microvessels demonstrates the diversity of innervation within the microcirculation. British Journal of Pharmacology, 107(S2), 453P. (doi:10.1111/j.1476-5381.1992.tb16283.x)

1991

Bulloch, J.M., MacDonald, A., Daly, C.J. and McGrath, J.C. (1991) Effect of cocaine on neurotransmission in rabbit isolated blood vessels. Fundamental and Clinical Pharmacology, 5(5), p. 454. (doi:10.1111/j.1472-8206.1991.tb00732.x)

Dunn, W.R., Daly, C.J. , McGrath, J.C. and Wilson, V.G. (1991) A comparison of the effects of angiotensin II and Bay K 8644 on responses to noradrenaline mediated via postjunctional α1-and α2-adrenoceptors in rabbit isolated blood vessels. British Journal of Pharmacology, 103(2), pp. 1475-1483. (doi:10.1111/j.1476-5381.1991.tb09814.x)

Dunn, W.R., Daly, C.J. , McGrath, J.C. and Wilson, V.G. (1991) The effects of nifedipine on alpha 2-adrenoceptor-mediated contractions in several isolated blood vessels from the rabbit. British Journal of Pharmacology, 103(2), pp. 1493-1499. (doi:10.1111/j.1476-5381.1991.tb09816.x)

Daly, C.J. and Wilson, V.G. (1991) Sympathetic neuroeffector transmission in the rabbit isolated saphenous vein. British Journal of Pharmacology, 102(S1), 98P. (doi:10.1111/j.1476-5381.1991.tb16274.x)

Daly, C. , Gordon, J.F. and McGrath, J. (1991) A fluorescence image analysis method for the study of smooth muscle cell interaction within the vascular wall of small blood vessels. Journal of Vascular Research, 28(4), p. 281. (doi:10.1159/000158878)

Daly, C.J. , Gordon, J.F. and McGrath, J.C. (1991) Assessment of cell viability within the wall of rat mesenteric arteries. Journal of Vascular Research, 28(4), p. 282. (doi:10.1159/000158878)

Daly, C.J. , Gordon, J.F. and McGrath, J.C. (1991) Fluorescence image analysis methods for the study of smooth muscle cell interaction within the vascular wall of small blood vessels. In: Mulvany, M. J. (ed.) Resistance Arteries, Structure and Function. Excerpta Medica: Amsterdam, pp. 339-343. ISBN 9780444891938

Daly, C.J. , Gordon, J.F., McGrath, J.C. and Spedding, M. (1991) Quantification of experimentally induced ischaemic damage to smooth muscle cell membranes within the wall of resistance arteries. Blood Vessels, 28(4), p. 281. (doi:10.1159/000158878)

1990

Bulloch, J.M., Daly, C.J. , Dunn, W.R., MacDonald, A. and McGrath, J.C. (1990) α,β-methylene ATP can potentiate as well as inhibit nerve mediated responses of rabbit blood vessels and guinea pig vas deferens. European Journal of Pharmacology, 183(2), pp. 543-544. (doi:10.1016/0014-2999(90)93450-5)

Daly, C.J. , McGrath, J.C. and Wilson, V.G. (1990) Activation of venous alpha2-adrenoceptors by UK-14304 in the presence of low extracellular Ca2+ is associated with an initial transient contraction. British Journal of Pharmacology, 100(S1), 465P. (doi:10.1111/j.1476-5381.1990.tb16988.x)

MacDonald, A., Daly, C.J. , Wilson, V.G. and McGrath, J.C. (1990) Effects of prejunctional a-adrenoceptor activation on neurotransmission in the rabbit saphenous artery. British Journal of Pharmacology, 99(S1), 53P. (doi:10.1111/j.1476-5381.1990.tb16587.x)

Daly, C.J. , Dunn, W.R., McGrath, J.C. , Miller, D.J. and Wilson, V.G. (1990) An examination of the sources of calcium for contractions mediated by postjunctional α1- and α2-adrenoceptors in several blood vessels isolated from the rabbit. British Journal of Pharmacology, 99(2), pp. 253-260. (doi:10.1111/j.1476-5381.1990.tb14690.x)

Daly, C.J. , McGrath, J.C. and Wilson, V.G. (1990) Angiotensin II selectively potentiates "innervated" post-junctional alpha2-adrenoceptors in the rabbit isolated plantaris vein. Journal of Autonomic Pharmacology, 10(1), 17P. (doi:10.1111/j.1474-8673.1990.tb00002.x)

Daly, C.J. , McGrath, J.C. and Wilson, V.G. (1990) Ca++ coupling mechanisms and veinous alpha2-adrenoceptors - the effect of angiotensin II. Journal of Autonomic Pharmacology, 10(1), 16P. (doi:10.1111/j.1474-8673.1990.tb00002.x)

Daly, C.J. , Gordon, J., Boyle, F.C., Gillespie, J.S., McGrath, J.C. , Moss, V.A. and Spurway, N.C. (1990) Fluorescent myography: the analysis of isolated vascular smooth muscle cells of the rat labelled with bisbenzamide during vasoconstriction. Journal of Physiology, 429(Suppl.), 11P.

Gordon, J.F., Daly, C.J. , Boyle, F.C., Kusel, J.R., Gillespie, J.S. and McGrath, J.C. (1990) A simple fluorescence-based cell viability assay for use in rat blood vessels in vitro. Journal of Physiology, 429(s), 10P.

Melville, C.A. , Trainor, M., McGrath, J.C. , Daly, C. , O'Dowd, J.J. and Miller, D.J. (1990) Carnosine shows alpha-adrenoceptor agonist and antagonist properties in saphenous vein isolated from rabbit. Journal of Physiology, 427(Suppl.), 29P.

McGrath, J.C. , Bulloch, J., Daly, C.J. and MacDonald, A. (1990) Contributions of different receptors to vasoconstrictor co-transmission in rabbit isolated arteries and veins. Journal of Vascular Research, 27(1), pp. 28-63. (doi:10.1159/000158794)

1989

Daly, C.J. , Dunn, W.R., McGrath, J. and Wilson, V.G. (1989) A Comparison of the actions of BAY K-8644 and angiotensin II on extracellular calcium-dependent contractile responses mediated by postjunctional alpha2-adrenoceptors. Annals of the New York Academy of Sciences, 560, pp. 440-443. (doi:10.1111/j.1749-6632.1989.tb24131.x)

Daly, C.J. , McGrath, J.C. and Wilson, V.G. (1989) Preliminary evidence for the release of cellular-bound calcium by post-junctional alpha2-adrenoceptors in the rabbit isolated ear vein. Journal of Physiology, 414(Suppl.), 57P.

McGrath, J.C. , Daly, C.J. , Dunn, W.R., MacDonald, A., Macmillan, J.B., Templeton, A.G.B. and Wilson, V.G. (1989) Variation in participation of postjunctional alpha1 and alpha2-adrenoceptors and P2y purinoceptors in vascular sympathetic co-transmission: modulation by drugs and hormones. In: XXXIst International Congress of Physiological Sciences, Helsinki, Finland, 9-14 Jul 1989, p. 4376.

McGrath, J.C. , Daly, C.J. , Dunn, W.R., MacLennan, S.J., Macmillan, J.B., Templeton, A.G.B. and Wilson, V.G. (1989) Physiological modulation of alpha-adreno- and 5HT- receptor expression in blood vessels. Journal of Vascular Medicine and Biology, 1, p. 187.

Wilson, V.G., McGrath, J.C. and Daly, C.J. (1989) Does basal release of an endothelium-derived relaxing factor modulate alpha-adrenoceptor function in the rabbit saphenous vein? Journal of Vascular Medicine and Biology, 1, p. 211.

1988

Bulloch, J.M., Daly, C.J. , MacDonald, A., McGrath, J.C. and Wilson, V.G. (1988) The effect of nifedipine on nerve-mediated responses of blood vessels in vitro and in vivo. British Journal of Pharmacology, 95(S1), 563P. (doi:10.1111/j.1476-5381.1988.tb16614.x)

Daly, C.J. , Dunn, W.R., McGrath, J.C. and Wilson, V.G. (1988) Effect of angiotensin II on responses to noradrenaline mediated via post-junctional alpha-1 and alpha2-adrenoceptors in isolated rabbit blood vessels. British Journal of Pharmacology, 95(S1), 475P-589P. (doi:10.1111/j.1476-5381.1988.tb16614.x)

Daly, C.J. , Dunn, W.R., McGrath, J.C. and Wilson, V.G. (1988) An attempt at selective protection from phenoxybenzamine of postjunctional α-adrenoceptor subtypes mediating contractions to noradrenaline in the rabbit isolated saphenous vein. British Journal of Pharmacology, 95(2), pp. 501-511. (doi:10.1111/j.1476-5381.1988.tb11670.x)

Daly, C.J. , McGrath, J.C. and Wilson, V.G. (1988) Pharmacological analysis of postjunctional α-adrenoceptors mediating contractions to (−)-noradrenaline in the rabbit isolated lateral saphenous vein can be explained by interacting responses to simultaneous activation of α1-and α2-adrenoceptors. British Journal of Pharmacology, 95(2), pp. 485-500. (doi:10.1111/j.1476-5381.1988.tb11669.x)

Daly, C.J. , McGrath, J.C. and Wilson, V.G. (1988) An examination of the postjunctional α-adrenoceptor subtypes for (−)-noradrenaline in several isolated blood vessels from the rabbit. British Journal of Pharmacology, 95(2), pp. 473-484. (doi:10.1111/j.1476-5381.1988.tb11668.x)

Daly, C.J. , McGrath, J.C. and Wilson, V.G. (1988) Evidence that the population of postjunctional-adrenoceptors mediating contraction of smooth muscle in the rabbit isolated ear vein is predominantly α2. British Journal of Pharmacology, 94(4), pp. 1085-1090. (doi:10.1111/j.1476-5381.1988.tb11626.x)

1987

Daly, C.J. , McGrath, J.C. and Wilson, V.G. (1987) α-Adrenoceptor-mediated contractions in the rabbit saphenous vein : the influence of endothelial cells. British Journal of Pharmacology, 92(S1), 776P. (doi:10.1111/j.1476-5381.1987.tb16603.x)

Daly, C.J. , McGrath, J.C. and Wilson, V.G. (1987) Isolation of post-junctional alpha2-adrenoceptors in the rabbit isolated saphenous vein with phenoxybenzamine. British Journal of Pharmacology, 92(S1), 775P. (doi:10.1111/j.1476-5381.1987.tb16603.x)

Dainty, I.A., Daly, C.J. , McGrath, J.C. , Sinclair, J. and Spedding, M. (1987) Measurement and analysis of analogue signals from a Linseis chart recorder using a BBC microcomputer. British Journal of Pharmacology, 91(Suppl.), p. 506.

Daly, C.J. , McGrath, J.C. and Wilson, V.G. (1987) Post-junctional alpha-adrenoceptors subtype(s) for(-)-noradrenaline in the rabbit isolated saphenous vein. British Journal of Pharmacology, 91(Suppl.), p. 397.

Dainty, I.A., Daly, C.J. , McGrath, J.C. , Sinclair, J. and Spedding, M. (1987) A simple, inexpensive method of collection, storage and analysis of data for the BBC microcomputer. In: Glasgow Meeting of the Physiological Society, Glasgow, UK, 19-20 Jun 1987, p. 22.

1985

Daly, C.J. , McGrath, J.C. , Muir, A.G.H. and O'Brien, J.W. (1985) Ca++-dependence of noradrenaline-induced contraction in rat aortic smooth muscle. British Journal of Pharmacology, 86(S2), 659P-815P. (doi:10.1111/j.1476-5381.1985.tb14737.x)

This list was generated on Thu Nov 21 16:49:51 2019 GMT.
Number of items: 131.

Articles

Alganga, H. S. F., Almabrouk, T. A.M. , Katwan, O. J., Daly, C. J. , Pyne, S., Pyne, N. J. and Kennedy, S. (2019) Short periods of hypoxia upregulate sphingosine kinase 1 and increase vasodilation of arteries to Sphingosine 1-phosphate via S1P3. Journal of Pharmacology and Experimental Therapeutics, 371(1), pp. 63-74. (doi:10.1124/jpet.119.257931) (PMID:31371480)

Garcia Cordoba, C. and Daly, C. J. (2019) The organisation of vascular smooth muscle cells; a quantitative Fast Fourier Transform (FFT) based assessment. Translational Research in Anatomy, 16, 100047. (doi:10.1016/j.tria.2019.100047)

Daly, C. J. (2019) From confocal microscope to virtual reality and computer games; technical and educational considerations. Infocus Magazine, 54, pp. 51-59.

Daly, C. J. (2018) The future of education? Using 3D animation and virtual reality in teaching physiology. Physiology News, 111(Summer), p. 43.

Nguyen, L. P. et al. (2017) β2-Adrenoceptor signaling in airway epithelial cells promotes eosinophilic inflammation, mucous metaplasia, and airway contractility. Proceedings of the National Academy of Sciences of the United States of America, 114(43), E9163-E9171. (doi:10.1073/pnas.1710196114) (PMID:29073113)

Patil, K. C. and Daly, C. J. (2017) Nanotechnology-based α1-adrenoceptor/gpr55 biomarker assay: molecular prognostic test for aggressive prostate cancer on the horizon? Socrates Almanac, 2017(8/2), pp. 20-22.

Abu Bakar, H., Dunn, W. R., Daly, C. and Ralevic, V. (2017) Sensory innervation of perivascular adipose tissue: a crucial role in artery vasodilatation and leptin release. Cardiovascular Research, 113(8), pp. 962-972. (doi:10.1093/cvr/cvx062) (PMID:28371926)

Daly, C.J. , Bulloch, J.M., Ma, M. and Aidulis, D. (2016) A comparison of animated versus static images in an instructional multimedia presentation. Advances in Physiology Education, 40(2), pp. 201-205. (doi:10.1152/advan.00053.2015) (PMID:27105738)

Patil, K. C., McPherson, L. and Daly, C. J. (2015) Co-localization of alpha1-adrenoceptors and GPR55: a novel prostate cancer paradigm? Pharmacology and Pharmacy, 6(4), pp. 212-220. (doi:10.4236/pp.2015.64023)

Bulloch, J. M. and Daly, C. J. (2014) Autonomic nerves and perivascular fat: interactive mechanisms. Pharmacology and Therapeutics, 143(1), pp. 61-73. (doi:10.1016/j.pharmthera.2014.02.005)

Shafaroudi, M. M. and Daly, C. J. (2014) Endothelial vasodilator angiotensin receptors are changing in mice with ageing. Research in Molecular Medicine, 2(1), pp. 26-34. (doi:10.18869/acadpub.rmm.2.1.26)

Daly, C. J. , Parmryd, I. and McGrath, J. C. (2012) Visualization and analysis of vascular receptors using confocal laser scanning microscopy and fluorescent ligands. Methods in Molecular Biology, 897, pp. 95-107. (doi:10.1007/978-1-61779-909-9_5)

Daly, C.J. and McGrath, J.C. (2011) Previously unsuspected widespread cellular and tissue distribution of β-adrenoceptors and its relevance to drug action. Trends in Pharmacological Sciences, 32(4), pp. 219-226. (doi:10.1016/j.tips.2011.02.008)

Daly, C.J., Ross, R.A., Whyte, J., Henstridge, C.M., Irving, A.J. and McGrath, J.C. (2010) Fluorescent ligand binding reveals heterogeneous distribution of adrenoceptors and ‘cannabinoid-like’ receptors in small arteries. British Journal of Pharmacology, 159(4), pp. 787-796. (doi:10.1111/j.1476-5381.2009.00608.x)

Davenport, A.P. and Daly, C.J. (2010) Imaging in pharmacology: editorial. British Journal of Pharmacology, 159(4), pp. 735-737. (doi:10.1111/j.1476-5381.2010.00685.x)

Clark, N.D.L. and Daly, C.J. (2010) Using confocal laser scanning microscopy to image trichome inclusions in amber. Journal of Paleontological Techniques, 8, pp. 1-7.

McGrath, J.C. , Methven, L., Hamill, C., Macmillan, J., Arribas, S., Briones, A., Vila, E. and Daly, C.J. (2008) Which vascular cells have adrenoceptors? Journal of Vascular Research, 45(Supple), 39--. (doi:10.1159/000113929)

Methven, L., Hamill, C., MacMillan, J., Daly, C.J. , McGrath, J.C. and Simpson, P.C. (2008) Functional responses in the a1AB- adrenoceptor knockout mouse indicate that the a1D- adrenoceptor has a role in the contraction of small mesenteric arteries. Journal of Vascular Research, 45(Supple), 45--. (doi:10.1159/000113929)

Hamill, C., Gonzalez, J.M., Methven, L., Daly, C.J. and McGrath, J.C. (2008) Approaches to visualising myoendothelial connections using laser scanning confocal microscopy. Journal of Vascular Research, 45(Supple), p. 8. (doi:10.1159/000113929)

Shafaroudi, M.M., Daly, C.J. and McGrath, J.C. (2008) Multiple action sites of alpha2-AR agonist (UK14304) on different adrenoreceptors in mice aorta. Journal of Damghan University of Basic Sciences, 1(3), pp. 111-122.

White, K., McGrath, J.C. and Daly, C.J. (2008) Selective delivery of dsRNA to resistance artery endothelial cells. Journal of Vascular Research, 45(Supple), p. 7. (doi:10.1159/000113929)

Arribas, S.M., Daly, C.J. , Gonzalez, M.C. and McGrath, J. (2007) Imaging the vascular wall using confocal microscopy. Journal of Physiology, 584(1), pp. 5-9. (doi:10.1113/jphysiol.2007.137786)

Morton, J.S., Daly, C.J. , Jackson, V.M. and McGrath, J.C. (2007) α1A-Adrenoceptors mediate contractions to phenylephrine in rabbit penile arteries. British Journal of Pharmacology, 150(1), pp. 112-120.

Briones, A. M., Daly, C. J. , Jimenez-Altayo, F., Martinez-Revelles, S., Gonzalez, J. M., McGrath, J. C. and Vila, E. (2005) Direct demonstration of β1- and evidence against β2- and β3-adrenoceptors, in smooth muscle cells of rat small mesenteric arteries. British Journal of Pharmacology, 146(5), pp. 679-691. (doi:10.1038/sj.bjp.0706369)

Briones, A. M., Daly, C. J. , Jimenez-Altayo, F., Martinez-Revelles, S., Gonzalez, J. M., McGrath, J. C. and Vila, E. (2005) Direct demonstration of β1- and evidence against β2- and β3-adrenoceptors, in smooth muscle cells of rat small mesenteric arteries. British Journal of Pharmacology, 146(5), pp. 679-691. (doi:10.1038/sj.bjp.0706369)

Daly, C. J. , McGrath, I. , Townsend, S. and Berkowitz, D. E. (2005) The role of the 1B-adrenergic receptor in vascular structure and function. Hypertension, 45(6), e20-e21. (doi:10.1161/01.HYP.0000167153.83102.15)

Gonzalez, J.M., Briones, A.M., Starcher, B., Conde, M.V., Somoza, B., Daly, C. , Vila, E., McGrath, I., Gonzalez, M.C. and Arribas, S.M. (2005) Influence of elastin on rat small artery mechanical properties. Experimental Physiology, 90, pp. 463-468. (doi:10.1113/expphysiol.2005.030056)

Miquel, M., Ali, Z., Segura, V., D'Ocon, M.P., Mcgrath, J. and Daly, C. (2005) 3D image analysis of fluorescent drug binding. Molecular Imaging, 4(1), pp. 1-13.

Morton, J.S., Daly, C.J. , Jackson, V.M., Van Der Graff, P.H. and McGrath, J. (2004) Development of an in vitro method to study penile resistance vessels using myography. Proceedings of the British Pharmacological Society, 11(4), 038P.

Briones, A.M., Gonzalez, J.M., Somoza, B., Giraldo, J., Daly, C.J. , Vila, E., Gonzalez, M.C., McGrath, J.C. and Arribas, S.M. (2003) Role of elastin in spontaneously hypertensive rat small mesenteric artery remodelling. Journal of Physiology, 552, pp. 185-195. (doi:10.1113/jphysiol.2003.046904)

McGrath, J.C. and Daly, C.J. (2003) Do fluorescent drugs show you more than you wanted to know? British Journal of Pharmacology, 139(2), pp. 187-189. (doi:10.1038/sj.bjp.0705288)

Coats, P., Jarajapu, Y., Hillier, C., McGrath, J. and Daly, C. (2003) The use of fluorescent nuclear dyes and laser scanning confocal microscopy to study the cellular aspects of arterial remodelling in human subjects with critical limb ischaemia. Experimental Physiology, 88, pp. 547-554.

Cockshott, W.P., Tao, Y.G., Gao, G., Balch, P., Briones, A.M. and Daly, C. (2003) Confocal microscopic image sequence compression using vector quantization and three-dimensional pyramid. Scanning, 25, pp. 247-256.

Hamid, S.A., Daly, C. and Campbell, S. (2003) Visualization of live endothelial cells ex vivo and in vitro. Microvascular Research, 66, pp. 159-163. (doi:10.1016/S0026-2862(03)00054-2)

Ali, Z., McGrath, J.C. and Daly, C.J. (2002) Characterisation of the contractile alpha1- adrenoceptor response in the mouse thoracic aorta. British Journal of Pharmacology, 137(Suppl.), 92P.

Brahmadevara, N., Macdonald, A., McGrath, J. and Daly, C. (2002) Measurement of cellular and tissue distribution of beta-adrenoceptors in rat thoracic aorta using BODIPY-CGP 12177. British Journal of Pharmacology, 137(Suppl.), 93P.

Daly, C. et al. (2002) Analysing the 3D structure of blood vessels using confocal microscopy. Microscopy and Analysis, 92, pp. 5-8.

Daly, C. , Pediani, J. , Mackenzie, J.F. and McGrath, J. (2002) Visualising agonist and antagonist interactions: the value of fluorescent ligands. Pharmacologist, 44(2), A73.

Jarajapu, Y.P.R., Macdonald, A., Hillier, C., McGrath, J. , Mackenzie, J.F. and Daly, C. (2002) Quantitative imaging of QAPB-associated fluorescence in smooth muscle cells from human skeletal muscle resistance arteries. British Journal of Pharmacology, 135(Suppl.), 303P.

McBride, M., Daly, C. and McGrath, J. (2002) Alpha1 and alpha2-adrenoceptors mediating resistance artery contraction as revealed by receptor “knockouts”. Pharmacologist, 44(2), A79.

McBride, M., Daly, C. and McGrath, J. (2002) Contractile responses to UK14304 are inhibited by low concentrations of rauwolscine but are unaffected by prazosin in mouse tail artery. British Journal of Pharmacology, 137(Suppl.), 91P.

McBride, M., Daly, C. and McGrath, J. (2002) Tail arteries from D79N mice show reduced responses to UK14304 compared with wild type. British Journal of Pharmacology, 135(Suppl.), 304P.

McGrath, J. and Daly, C. (2002) Fluorescence technologies for the study of receptors. Pharmacologist, 44(2), A73.

Shafaroudi, M., Daly, C. and McGrath, J. (2002) Analysis of alpha2-adrenoceptor- and angiotensin-mediated responses in mouse aorta. Pharmacologist, 44(2), A79.

Shang, C., McGrath, J. , Daly, C. and Barker, J. (2000) Modelling and classification of vascular smooth muscle cell images. Electronics Letters, 36(18), pp. 1532-1533. (doi:10.1049/el:20001106)

Mackenzie, J. F., Daly, C. J., Pediani, J. D. and McGrath, J. C. (2000) Quantitative imaging in live human cells reveals intracellular alpha(1)-adrenoceptor ligand-binding sites. Journal of Pharmacology and Experimental Therapeutics, 294(2), pp. 434-443.

Pediani, J. D. , Mackenzie, J. F., Heeley, R. P., Daly, C. J. and McGrath, J. C. (2000) Single-cell recombinant pharmacology: bovine α1a-adrenoceptors in rat-1 fibroblasts release intracellular Ca2+, display subtype-characteristic agonism and antagonism, and exhibit an antagonist-reversible inverse concentration-response phase. Journal of Pharmacology and Experimental Therapeutics, 293(3), pp. 887-895.

Shaw, A. M., Bunton, D. C., Fisher, A., McGrath, J. C. , Montgomery, I., Daly, C. and MacDonald, A. (1999) V-shaped cushion at the origin of bovine pulmonary supernumerary arteries: structure and putative function. Journal of Applied Physiology, 87(6), pp. 2348-2356.

McGrath, J.C. , Mackenzie, J.F. and Daly, C. J. (1999) Pharmacological implications of cellular localization of α1-adrenoceptors in native smooth muscle cells. Journal of Autonomic Pharmacology, 19(6), pp. 303-310. (doi:10.1111/j.1365-2680.1999.tb00002.x)

Mackenzie, J.F., Daly, C.J. , Luo, D. and McGrath, J.C. (1999) Cellular localisation of alpha1 -adrenoceptors in human primary smooth muscle cells derived from the prostate of patients with benign prostatic hypertrophy. European Urology, 36(S1), p. 115. (doi:10.1159/000052331)

McGrath, J.C. , Nagadeh, M.A., Pediani, J.D. , Mackenzie, J.F. and Daly, C.J. (1999) Importance of agonists in α-adrenoceptor classification and localisation of α1-adrenoceptors in human prostate. European Urology, 36(S1), pp. 80-88. (doi:10.1159/000052326)

Luo, D., Barker, J., McGrath, J.C. and Daly, C.J. (1998) Iterative multilevel thresholding and splitting for 3D segmentation of live cell nuclei using laser scanning confocal microscopy. Journal of Computer-Assisted Microscopy, 10(4), pp. 151-162. (doi:10.1023/A:1023482003483)

Daly, C.J. , Milligan, C.M., Milligan, G. , Mackenzie, J.F. and McGrath, J.C. (1998) Cellular localization and pharmacological characterization of functioning alpha-1 adrenoceptors by fluorescent ligand binding and image analysis reveals identical binding properties of clustered and diffuse populations of receptors. Journal of Pharmacology and Experimental Therapeutics, 286(2), pp. 984-990.

Daly, C.J. , Milligan, C.M., Milligan, G. , Mackenzie, J.F. and McGrath, J.C. (1998) Cellular localization and pharmacological characterization of functioning alpha-1 adrenoceptors by fluorescent ligand binding and image analysis reveals identical binding properties of clustered and diffuse populations of receptors. Journal of Pharmacology and Experimental Therapeutics, 286(2), pp. 984-990.

Daly, C.J. , Cotecchia, S. and McGrath, J.C. (1998) Low frequency electrical field stimulation elicits responses in segments of mouse tail artery which are slower in alpha1B-knockout mice than in control mice. Naunyn-Schmiedeberg's Archives of Pharmacology, 358(S2), P6.40.

Giummelly, P., Colas, T., Atkinson, J., Robert, A., Daly, C.J. , Luo, D. and McGrath, J.C. (1998) Fluorescence of the medial aortic elastic lamella in elastocalcinotic rats. Naunyn-Schmiedeberg's Archives of Pharmacology, 358(S1), P37.36.

Luo, D., Daly, C.J. , Mackenzie, J.F., McGrory, S.P., Robert, A. and McGrath, J.C. (1998) 3D remodelling of alpha1-adrenoceptors in live cells using a fluorescent ligand, QAPB and confocal laser scanning microscopy. Naunyn-Schmiedeberg's Archives of Pharmacology, 358(S2), P6.44.

Mackenzie, J.F., Daly, C.D. and McGrath, J.C. (1998) Comparison and validation of human a1-adrenoceptor binding characteristics on live, whole cells using radioligand binding and confocal laser scanning microscopic techniques. Naunyn-Schmiedeberg's Archives of Pharmacology, 358(S2), P6.45.

Pediani, J. , Mackenzie, J.F., Daly, C. and McGrath, J. (1998) Comparison of functional and binding pharmacological properties of the cloned bovine a 1a-adrenoceptor (a 1a-AR) stably expressed in rat-1 fibroblasts. Naunyn-Schmiedeberg's Archives of Pharmacology, 358(S2), P6.47.

Robert, A., Daly, C.J. , Luo, D., Montgomery, I. and McGrath, J.C. (1998) Decrease of the medial carotid elastin componentin rabbit ligated coronary heart failure model. Naunyn-Schmiedeberg's Archives of Pharmacology, 358(S2), P57.22.

Daly, C.J., , de la Rue, S.A., Luo, D. and McGrath, J.C. (1997) 3D-distribution of a-adrenoceptors in blood vessel lack of staining on endothelial cells. Journal of Vascular Research, 34(Sup 1), p. 34. (doi:10.1159/000317489)

McGrath, J. C. , Arribas, S. and Daly, C. J. (1996) Fluorescent ligands for the study of receptors. Trends in Pharmacological Sciences, 17(11), pp. 393-399. (doi:10.1016/S0165-6147(96)40004-9)

Arribas, S. M., Gordon, J. F., Daly, C. J. , Dominiczak, A. F. and McGrath, J. C. (1996) Confocal microscopic characterization of a lesion in a cerebral vessel of the stroke-prone spontaneously hypertensive rat. Stroke, 27(6), pp. 1118-1123. (doi:10.1161/01.STR.27.6.1118)

McGrath, J. and Daly, C. (1996) Functional antagonism and receptor-induced fluorescence in rat anococcygeus. FASEB Journal, 10(3), p. 2448.

McGrath, J.C. , Arribas, S., Daly, C.J. and Gordon, J.F. (1995) Confocal microscopy for structure and realtime pharmacology in blood vessels. Journal of Human Hypertension, 9(8), pp. 645-647.

McGrath, J.C. et al. (1995) The relationship between the adrenoceptor and nonadrenoceptor-mediated effects of imidazoline- and imidazole-containing compounds. Annals of the New York Academy of Sciences, 763(1), pp. 591-605. (doi:10.1111/j.1749-6632.1995.tb32454.x)

Shakur, Y., Wilson, M., Pooley, L., Lobban, M., Griffiths, S.L., Campbell, A.M., Beattie, J., Daly, C. and Houslay, M.D. (1995) Identification and characterization of the type-IVA cyclic AMP-specific phosphodiesterase RD1 as a membrane-bound protein expressed in cerebellum. Biochemical Journal, 306, pp. 801-809.

Arribas, S., Daly, C. , Dominiczak, A. and McGrath, J. (1995) Reduced vasodilator responses to noradrenaline correlates with decreased density of -adrenoceptor flurophore binding in the basilar artery from old WKY rats. Methods and Finding in Experimental and Clinical Pharmacology, 17, CO30.

McGrath, J. and Daly, C. (1995) Viewing adrenoceptors; past, present, and future; commentary and a new technique. Pharmacology Communications, 1(6), pp. 269-279.

Arribas, S., Gordon, J.F., Daly, C. , Davidson, A., Dominiczak, A. and McGrath, J.C. (1994) Vascular smooth muscle rearrangement and impaired contractions in basilar artery of the stroke-prone spontaneously hypertensive rat. Journal of Hypertension, 12(11), p. 1319.

Daly, C.J. , Gordon, J.F. and McGrath, J.C. (1994) The use of confocal microscopy for the study of resistance artery structure and function. Journal of Vascular Research, 31(Sup 1), p. 10. (doi:10.1159/000159068)

Macmillan, J.M., Daly, C.J. and McGrath, J.C. (1994) The innervation and alpha-adrenoceptor profile of rabbit isolated dorsal cutaneous and sub-cutaneous resistance arteries. Journal of Vascular Research, 31(Sup 1), p. 30. (doi:10.1159/000317452)

Gordon, J.F., Baird, M., Daly, C.J. and McGrath, J.C. (1992) Endogenous nitric oxide modulates sympathetic neuroeffector transmission in the isolated rabbit lateral saphenous vein. Journal of Cardiovascular Pharmacology, 20(Sup 12), S68-S71.

MacDonald, A., Daly, C.J. , Bulloch, J.M. and McGrath, J.C. (1992) Contributions of α1-adrenoceptors, α2-adrenoceptors and P2x-purinoceptors to neurotransmission in several rabbit isolated blood vessels: role of neuronal uptake and autofeedback. British Journal of Pharmacology, 105(2), pp. 347-354. (doi:10.1111/j.1476-5381.1992.tb14257.x)

Clinch, N.F., Daly, C.J. , Gordon, J.F., Moss, V.A. and Spurway, N.C. (1992) Wide-field volume visualisation of thick microscope sections by computed nearest neighbour deconvolutions. Journal of Physiology, 452, 3P.

Daly, C.J. , Gordon, J.F. and McGrath, J.C. (1992) Endogenous nitric oxide modulates sympathetic neuroeffector transmission in the rabbit isolated lateral saphenous vein. Journal of Vascular Research, 29(2), p. 99. (doi:10.1159/000317442)

Daly, C.J. , Gordon, J.F. and McGrath, J.C. (1992) The use of fluorescent nuclear dyes for the study of blood vessel structure and function: novel applications of existing techniques. Journal of Vascular Research, 29(1), pp. 41-48. (doi:10.1159/000158930)

Daly, C.J. , MacLean, M.R. and McGrath, J.C. (1992) Electrical field stimulation of rabbit isolated cutaneous and pulmonary microvessels demonstrates the diversity of innervation within the microcirculation. British Journal of Pharmacology, 107(S2), 453P. (doi:10.1111/j.1476-5381.1992.tb16283.x)

Bulloch, J.M., MacDonald, A., Daly, C.J. and McGrath, J.C. (1991) Effect of cocaine on neurotransmission in rabbit isolated blood vessels. Fundamental and Clinical Pharmacology, 5(5), p. 454. (doi:10.1111/j.1472-8206.1991.tb00732.x)

Dunn, W.R., Daly, C.J. , McGrath, J.C. and Wilson, V.G. (1991) A comparison of the effects of angiotensin II and Bay K 8644 on responses to noradrenaline mediated via postjunctional α1-and α2-adrenoceptors in rabbit isolated blood vessels. British Journal of Pharmacology, 103(2), pp. 1475-1483. (doi:10.1111/j.1476-5381.1991.tb09814.x)

Dunn, W.R., Daly, C.J. , McGrath, J.C. and Wilson, V.G. (1991) The effects of nifedipine on alpha 2-adrenoceptor-mediated contractions in several isolated blood vessels from the rabbit. British Journal of Pharmacology, 103(2), pp. 1493-1499. (doi:10.1111/j.1476-5381.1991.tb09816.x)

Daly, C.J. and Wilson, V.G. (1991) Sympathetic neuroeffector transmission in the rabbit isolated saphenous vein. British Journal of Pharmacology, 102(S1), 98P. (doi:10.1111/j.1476-5381.1991.tb16274.x)

Daly, C. , Gordon, J.F. and McGrath, J. (1991) A fluorescence image analysis method for the study of smooth muscle cell interaction within the vascular wall of small blood vessels. Journal of Vascular Research, 28(4), p. 281. (doi:10.1159/000158878)

Daly, C.J. , Gordon, J.F. and McGrath, J.C. (1991) Assessment of cell viability within the wall of rat mesenteric arteries. Journal of Vascular Research, 28(4), p. 282. (doi:10.1159/000158878)

Daly, C.J. , Gordon, J.F., McGrath, J.C. and Spedding, M. (1991) Quantification of experimentally induced ischaemic damage to smooth muscle cell membranes within the wall of resistance arteries. Blood Vessels, 28(4), p. 281. (doi:10.1159/000158878)

Bulloch, J.M., Daly, C.J. , Dunn, W.R., MacDonald, A. and McGrath, J.C. (1990) α,β-methylene ATP can potentiate as well as inhibit nerve mediated responses of rabbit blood vessels and guinea pig vas deferens. European Journal of Pharmacology, 183(2), pp. 543-544. (doi:10.1016/0014-2999(90)93450-5)

Daly, C.J. , McGrath, J.C. and Wilson, V.G. (1990) Activation of venous alpha2-adrenoceptors by UK-14304 in the presence of low extracellular Ca2+ is associated with an initial transient contraction. British Journal of Pharmacology, 100(S1), 465P. (doi:10.1111/j.1476-5381.1990.tb16988.x)

MacDonald, A., Daly, C.J. , Wilson, V.G. and McGrath, J.C. (1990) Effects of prejunctional a-adrenoceptor activation on neurotransmission in the rabbit saphenous artery. British Journal of Pharmacology, 99(S1), 53P. (doi:10.1111/j.1476-5381.1990.tb16587.x)

Daly, C.J. , Dunn, W.R., McGrath, J.C. , Miller, D.J. and Wilson, V.G. (1990) An examination of the sources of calcium for contractions mediated by postjunctional α1- and α2-adrenoceptors in several blood vessels isolated from the rabbit. British Journal of Pharmacology, 99(2), pp. 253-260. (doi:10.1111/j.1476-5381.1990.tb14690.x)

Daly, C.J. , McGrath, J.C. and Wilson, V.G. (1990) Angiotensin II selectively potentiates "innervated" post-junctional alpha2-adrenoceptors in the rabbit isolated plantaris vein. Journal of Autonomic Pharmacology, 10(1), 17P. (doi:10.1111/j.1474-8673.1990.tb00002.x)

Daly, C.J. , McGrath, J.C. and Wilson, V.G. (1990) Ca++ coupling mechanisms and veinous alpha2-adrenoceptors - the effect of angiotensin II. Journal of Autonomic Pharmacology, 10(1), 16P. (doi:10.1111/j.1474-8673.1990.tb00002.x)

Daly, C.J. , Gordon, J., Boyle, F.C., Gillespie, J.S., McGrath, J.C. , Moss, V.A. and Spurway, N.C. (1990) Fluorescent myography: the analysis of isolated vascular smooth muscle cells of the rat labelled with bisbenzamide during vasoconstriction. Journal of Physiology, 429(Suppl.), 11P.

Gordon, J.F., Daly, C.J. , Boyle, F.C., Kusel, J.R., Gillespie, J.S. and McGrath, J.C. (1990) A simple fluorescence-based cell viability assay for use in rat blood vessels in vitro. Journal of Physiology, 429(s), 10P.

Melville, C.A. , Trainor, M., McGrath, J.C. , Daly, C. , O'Dowd, J.J. and Miller, D.J. (1990) Carnosine shows alpha-adrenoceptor agonist and antagonist properties in saphenous vein isolated from rabbit. Journal of Physiology, 427(Suppl.), 29P.

McGrath, J.C. , Bulloch, J., Daly, C.J. and MacDonald, A. (1990) Contributions of different receptors to vasoconstrictor co-transmission in rabbit isolated arteries and veins. Journal of Vascular Research, 27(1), pp. 28-63. (doi:10.1159/000158794)

Daly, C.J. , Dunn, W.R., McGrath, J. and Wilson, V.G. (1989) A Comparison of the actions of BAY K-8644 and angiotensin II on extracellular calcium-dependent contractile responses mediated by postjunctional alpha2-adrenoceptors. Annals of the New York Academy of Sciences, 560, pp. 440-443. (doi:10.1111/j.1749-6632.1989.tb24131.x)

Daly, C.J. , McGrath, J.C. and Wilson, V.G. (1989) Preliminary evidence for the release of cellular-bound calcium by post-junctional alpha2-adrenoceptors in the rabbit isolated ear vein. Journal of Physiology, 414(Suppl.), 57P.

McGrath, J.C. , Daly, C.J. , Dunn, W.R., MacLennan, S.J., Macmillan, J.B., Templeton, A.G.B. and Wilson, V.G. (1989) Physiological modulation of alpha-adreno- and 5HT- receptor expression in blood vessels. Journal of Vascular Medicine and Biology, 1, p. 187.

Wilson, V.G., McGrath, J.C. and Daly, C.J. (1989) Does basal release of an endothelium-derived relaxing factor modulate alpha-adrenoceptor function in the rabbit saphenous vein? Journal of Vascular Medicine and Biology, 1, p. 211.

Bulloch, J.M., Daly, C.J. , MacDonald, A., McGrath, J.C. and Wilson, V.G. (1988) The effect of nifedipine on nerve-mediated responses of blood vessels in vitro and in vivo. British Journal of Pharmacology, 95(S1), 563P. (doi:10.1111/j.1476-5381.1988.tb16614.x)

Daly, C.J. , Dunn, W.R., McGrath, J.C. and Wilson, V.G. (1988) Effect of angiotensin II on responses to noradrenaline mediated via post-junctional alpha-1 and alpha2-adrenoceptors in isolated rabbit blood vessels. British Journal of Pharmacology, 95(S1), 475P-589P. (doi:10.1111/j.1476-5381.1988.tb16614.x)

Daly, C.J. , Dunn, W.R., McGrath, J.C. and Wilson, V.G. (1988) An attempt at selective protection from phenoxybenzamine of postjunctional α-adrenoceptor subtypes mediating contractions to noradrenaline in the rabbit isolated saphenous vein. British Journal of Pharmacology, 95(2), pp. 501-511. (doi:10.1111/j.1476-5381.1988.tb11670.x)

Daly, C.J. , McGrath, J.C. and Wilson, V.G. (1988) Pharmacological analysis of postjunctional α-adrenoceptors mediating contractions to (−)-noradrenaline in the rabbit isolated lateral saphenous vein can be explained by interacting responses to simultaneous activation of α1-and α2-adrenoceptors. British Journal of Pharmacology, 95(2), pp. 485-500. (doi:10.1111/j.1476-5381.1988.tb11669.x)

Daly, C.J. , McGrath, J.C. and Wilson, V.G. (1988) An examination of the postjunctional α-adrenoceptor subtypes for (−)-noradrenaline in several isolated blood vessels from the rabbit. British Journal of Pharmacology, 95(2), pp. 473-484. (doi:10.1111/j.1476-5381.1988.tb11668.x)

Daly, C.J. , McGrath, J.C. and Wilson, V.G. (1988) Evidence that the population of postjunctional-adrenoceptors mediating contraction of smooth muscle in the rabbit isolated ear vein is predominantly α2. British Journal of Pharmacology, 94(4), pp. 1085-1090. (doi:10.1111/j.1476-5381.1988.tb11626.x)

Daly, C.J. , McGrath, J.C. and Wilson, V.G. (1987) α-Adrenoceptor-mediated contractions in the rabbit saphenous vein : the influence of endothelial cells. British Journal of Pharmacology, 92(S1), 776P. (doi:10.1111/j.1476-5381.1987.tb16603.x)

Daly, C.J. , McGrath, J.C. and Wilson, V.G. (1987) Isolation of post-junctional alpha2-adrenoceptors in the rabbit isolated saphenous vein with phenoxybenzamine. British Journal of Pharmacology, 92(S1), 775P. (doi:10.1111/j.1476-5381.1987.tb16603.x)

Dainty, I.A., Daly, C.J. , McGrath, J.C. , Sinclair, J. and Spedding, M. (1987) Measurement and analysis of analogue signals from a Linseis chart recorder using a BBC microcomputer. British Journal of Pharmacology, 91(Suppl.), p. 506.

Daly, C.J. , McGrath, J.C. and Wilson, V.G. (1987) Post-junctional alpha-adrenoceptors subtype(s) for(-)-noradrenaline in the rabbit isolated saphenous vein. British Journal of Pharmacology, 91(Suppl.), p. 397.

Daly, C.J. , McGrath, J.C. , Muir, A.G.H. and O'Brien, J.W. (1985) Ca++-dependence of noradrenaline-induced contraction in rat aortic smooth muscle. British Journal of Pharmacology, 86(S2), 659P-815P. (doi:10.1111/j.1476-5381.1985.tb14737.x)

Book Sections

Daly, C. J. (2019) Examining vascular structure and function using confocal microscopy and 3D imaging techniques. In: Rea, P. M. (ed.) Biomedical Visualisation. Series: Advances in experimental medicine and biology (1120). Springer: Cham, pp. 97-106. ISBN 9783030060695 (doi:10.1007/978-3-030-06070-1_8)

Daly, C. J. (2019) Imaging the vascular wall: from microscope to virtual reality. In: Touyz, R. M. and Delles, C. (eds.) Textbook of Vascular Medicine. Springer: Cham, pp. 59-66. ISBN 9783030164805 (doi:10.1007/978-3-030-16481-2_6)

McGrath, J. C. and Daly, C. J. (2006) Use of fluorescent ligands and receptors to visualize adrenergic receptors. In: Perez, D. M. (ed.) The Adrenergic Receptors: In the 21st Century. Series: The receptors, III. Humana Press, pp. 151-172. ISBN 9781588294234 (doi:10.1385/1-59259-931-1:151)

Arriba, S.M., Daly, C.J. , Gordon, J.F. and McGrath, J.C. (1994) Confocal myography: applications for the study of resistance arteries. In: Halpern, W., Bevan, J.A., Brayden, J., Dustan, H. and Nelson, M. (eds.) The Resistance Arteries: Integration of the Regulatory Pathways. Series: Experimental biology and medicine (26). Humana Press: New York, NY, pp. 259-264. ISBN 9781617370083

Daly, C.J. , Gordon, J.F. and McGrath, J.C. (1991) Fluorescence image analysis methods for the study of smooth muscle cell interaction within the vascular wall of small blood vessels. In: Mulvany, M. J. (ed.) Resistance Arteries, Structure and Function. Excerpta Medica: Amsterdam, pp. 339-343. ISBN 9780444891938

Conference Proceedings

Daly, C.J. , Wallace, G., White, K., Henstridge, C., Irving, A. and McGrath, J.C. (2008) Visualisation of Vascular Cannabinoid Receptors and their Potential Interaction with alpha1-adrenergic Receptors. In: Vascular and Smooth Muscle Physiology. Themed Meeting of the Physiological Society, King's College, London, December 2008,

Morton, J.S., Daly, C.J. , McGrath, J.C. and Jackson, V.M. (2005) Development of an in vitro method to study vaginal arteries using myography. In: University of Newcastle Winter Meeting, Newcastle, UK, 2005,

McBride, M., Daly, C. and McGrath, J. (2002) Contractile responses to UK 14304 in the mouse tail artery differ when the drug is administered cumulatively or non-cumulatively. In: 7th Annual Meeting of the European Council for Blood Pressure and Cardiovascular Research (ECCR), Seeheim, Germany, 11-13 Oct 2002,

Daly, C.J. , Vila, E., Arribas, S.M., Pagakis, S., Thebault, B., Maddison, J., Pederson, J. and McGrath, J.C. (2000) 3-dimensional analysis of vascular structure, function & receptor distribution using confocal laser scanning microscopy. In: 10th Porto Meeting on Adrenergic Mechanisms, Porto, Portugal, 25-27 Sep 2000,

Granitsioti, P., Daly, C. , Kirk, D. and McGrath, J. (2000) Physiology of the human vas deferens; Clinical importance. In: 10th Porto Meeting on Adrenergic Mechanisms, Porto, Portugal, 25-27 Sept 2000,

Mackenzie, J.F., Pediani, J. , Daly, C. , Deighan, C. and McGrath, J. (2000) Fluorescent ligand binding to alpha1-adrenoceptors in murine hepatocytes. In: 10th Porto Meeting on Adrenergic Mechanisms, Porto, Portugal, 25-27 Sept 2000, P2.

Shang, C., Daly, C. , McGrath, J. and Barker, J. (2000) Neural network based classification of cell images via estimation of fractal dimensions. In: International Conference on Artificial Neural Networks in Medicine and Biology, Goteburg, Sweden, 13-16 May 2000, pp. 111-116. (doi:10.1007/978-1-4471-0513-8_15)

McGrath, J.C. , Mackenzie, J.F. and Daly, C.J. (1999) Sub-cellular localisation of alpha1-adrenoceptors in live cells and tissues. In: British Pharmacological Societ Joint Spring Meeting with Portuguese Pharmacological Society, Porto, Portugal, 8-9 Apr 1999, 133P.

Robert, A., Daly, C.J. and McGrath, J.C. (1998) Decrease of in vitro carotid compliance in rabbit heart failure model. In: Heart Failure Update, Glasgow, UK, 1998, p. 8.

Arribas, S.M., Gordon, J.F., Daly, C.J. , Davidson, A., Dominiczak, A. and McGrath, J.C. (1995) Structural and functional alterations in the basilar artery from stroke prone spontaneously hypertensive rats. In: 7th European Meeting on Hypertension, Milan, Italy, 9-12 Jun 1995, p. 12.

Daly, C.J. , Gordon, J.F. and McGrath, J.C. (1993) Dimensional analysis of smooth muscle cell reactivity within the rat resistance artery using confocal microscopy. In: XXXII Congress of the International Union of Physiological Sciences, Glasgow, UK, 1-6 Aug 1993,

Daly, C.J. , Gordon, J.F. and McGrath, J.C. (1993) Observation of vasodilatation in small arteries with confocal microscopy. In: XXXII Congress of the International Union of Physiological Sciences, Glasgow, UK, 1-6 Aug 1993,

Gordon, J.F., Daly, C.J. and McGrath, J.C. (1993) Analysis of rat resistance artery structure in pressurised vessels using confocal microscopy. In: XXXII Congress of the International Union of Physiological Sciences, Glasgow, UK, 1-6 Aug 1993,

Moss, V.A., Gordon, J.F. and Daly, C.J. (1993) Software for the automated determination of 3-D coordinates of cell nuclei labelled with fluorescent dyes imaged using confocal microscopy. In: XXXII Congress of the International Union of Physiological Sciences, Glasgow, UK, 1-6 Aug 1993,

McGrath, J.C. , Daly, C.J. , Dunn, W.R., MacDonald, A., Macmillan, J.B., Templeton, A.G.B. and Wilson, V.G. (1989) Variation in participation of postjunctional alpha1 and alpha2-adrenoceptors and P2y purinoceptors in vascular sympathetic co-transmission: modulation by drugs and hormones. In: XXXIst International Congress of Physiological Sciences, Helsinki, Finland, 9-14 Jul 1989, p. 4376.

Dainty, I.A., Daly, C.J. , McGrath, J.C. , Sinclair, J. and Spedding, M. (1987) A simple, inexpensive method of collection, storage and analysis of data for the BBC microcomputer. In: Glasgow Meeting of the Physiological Society, Glasgow, UK, 19-20 Jun 1987, p. 22.

This list was generated on Thu Nov 21 16:49:51 2019 GMT.

Teaching

As a course coordinator (physiology, autonomic nervous system & bioimaging), I have also become interested in the use of animation for teaching.

My novel approach is to combine 3D laser scanning microscopy with Pixar-style animation software. The resulting animations are anatomically correct to within 0.1mm and are therefore not ‘artists impressions’ (unlike most physiology-based animations you will find on YouTube). 

My educational research focusses on the application of cognitive load theory and multimedia principles in the design of 3D animations and VR content.

Click here to view my YouTube Channel

I am currently the external examiner for Human Biology at Glasgow Caledonian University (2013-2018) and also for the BSc in BioMedical Sciences at Nottingham University (2017-2021).

I have acted as an examiner (internal and external) for over 20 PhD students.


Additional information

Invited International Presentations

  • 2018: Glasgow, Scotland, UK - Glasgow University Teaching & Learning Conference. Oral presentation. ‘3D animations and VR for teaching in higher education’.
  • 2017: London, England, UK - Pharmacology 2017 London. Oral presentation. ‘The design of 3D multimedia’.
  • 2016: Dublin, Ireland - Physiology 2016 Dublin. Oral presentation. ‘Cognitive loading in 3D animations’.
  • 2015: Uppsala University, Sweden - Guest Lecture & Teaching Session: "Image Analysis of the Vascular Wall"
  • 2009: Edinburgh, UK - Pharmacological Society Meeting, Organised and Chaired Symposium 'Imaging Receptors'
  • 2007: Glasgow, UK - Life Science 2007, Organised and Chaired Symposium 'Imaging in the Life Sciences'
  • 2005: London, UK - Pharmacological Society Meeting, Organised and Chaired Symposium 'Fluorescence technologies for studying receptors'
  • 2004: Washington DC, USA. - Experimental Biology. Studies with Fluorescent ligands.
  • 2002: San Francisco, USA. - IUPHAR. 'Studying agonist and antagonist kinetics using fluorescent ligands'.
  • 2002: Lake Tahoe, USA. - Vascular Neuroeffector Mechanisms. 'Receptor distribution through the vascular wall'.
  • 2002: Glasgow, UK - Physiological Society Meeting - Organised and Chaired Symposium: The Use of Transgenic Animals
  • 2001: Vancouver, Canada. - Pharmacology 2001. 'The use of fluorescent ligands for the study of receptors'.
  • 2000: Edinburgh, UK - University of Edinburgh - Seminar Series. 'Imaging Blood Vessels
  • 1999: Oxford, UK - Oxford University - Seminar Series. 'Vascular Receptor Distribution
  • 1998: London, UK - Royal College of Surgeons. 3D structure of arteries

Prizes, Awards and Distinctions

  • 2017: British Pharmacological Society - Awarded ‘Best Oral Communication’ in the education section at Pharmacology 2017
  • 2017: United Kingdom - Senior Fellow of the Higher Education Academy
  • 2017: British Pharmacological Society - Teaching award (grant). ‘Construction of 3D resources for teaching pharmacology’.
  • 2013: Physiological Society - David Jordan Teaching Award - 'Creation of anatomically accurate 3D animations for teaching physiology'

Professional Learned Society

  • 2005 - present: Physiological Society - Member & Society Representative at Glasgow University
  • 2001 - present: British Pharmacological Society - Member. Co-ordinator of the special interest group in Imaging 2004-