Dr Elihu Aranday-Cortes

  • Research Associate (Virology)

telephone: 01413302988
email: Elihu.Aranday-Cortes@glasgow.ac.uk
pronouns: He/him/his

464 Bearsden Road, Centre for Virus Research, Henry Wellcome Building, Room 413 Level 4,, Glasgow, G61 1QH

ORCID iDhttps://orcid.org/0000-0003-2637-2307

Biography

I studied Veterinary Medicine at Universidad Nacional Autonoma de Mexico and completed a PhD in Clinical Medicine Research at Imperial College London in conjunction with the Animal Health and Veterinary Research Agency, focusing in bovine tuberculosis.

Research interests

CVR logo 

 

I am a Research Associate at the MRC-University of Glasgow Centre for Virus Research in Prof John McLauchlan’s group, where for the last three years, I have been involved in projects related to innate immune response to viruses as well as virus diversity in hepatitis C (HCV) and dengue virus (DENV).

I have an active role in collaborative studies with the Philippines and Indonesia, both supported by MRC:Newton Funding, in which the main objective is to correlate disease severity in DENV-infected patients, who have well-defined clinical outcomes, with host transcriptomic and proteomic changes observed in the periphery. This will allow us to identify candidate virological and/or host biomarkers for the development of diagnostic platforms that predict progression to severe disease.

Publications

Selected publications

Aranday-Cortes, E. , Kaveh, D., Nunez-Garcia, J., Hogarth, P. J. and Vordermeier, H. M. (2010) Mycobacterium bovis-BCG vaccination induces specific pulmonary transcriptome biosignatures in mice. PLoS ONE, 5(6), e11319. 20596522. (doi: 10.1371/journal.pone.0011319) (PMID:PMC2893133)

Bhuju, S., Aranday-Cortes, E. , Villarreal-Ramos, B., Xing, Z., Singh, M. and Vordermeier, H. M. (2012) Global gene transcriptome analysis in vaccinated cattle revealed a dominant role of IL-22 for protection against bovine tuberculosis. PLoS Pathogens, 8(12), e1003077. (doi: 10.1371/journal.ppat.1003077)

Aranday-Cortes, E. , Bull, N.C., Villarreal-Ramos, B., Gough, J., Hicks, D., Ortiz-Peláez, A., Vordermeier, H.M. and Salguero, F.J. (2013) Upregulation of IL-17A, CXCL9 and CXCL10 in early-stage granulomas induced by Mycobacterium bovis in cattle. Transboundary and Emerging Diseases, 60(6), pp. 525-537. (doi: 10.1111/j.1865-1682.2012.01370.x)

Robinson, M. W. et al. (2015) Viral genotype correlates with distinct liver gene transcription signatures in chronic hepatitis C virus infection. Liver International, 35(10), pp. 2256-2264. (doi: 10.1111/liv.12830) (PMID:25800823) (PMCID:PMC4949513)

Aranday-Cortes, E. , Hogarth, P. J., Kaveh, D. A., Whelan, A. O., Villarreal-Ramos, B., Lalvani, A. and Vordermeier, H. M. (2012) Transcriptional profiling of disease-induced host responses in bovine tuberculosis and the identification of potential diagnostic biomarkers. PLoS ONE, 7(2), e30626. (doi: 10.1371/journal.pone.0030626)

All publications

List by: Type | Date

Jump to: 2022 | 2021 | 2019 | 2018 | 2017 | 2015 | 2013 | 2012 | 2010
Number of items: 24.

2022

Aranday-Cortes, E. et al. (2022) Real-world outcomes of direct-acting antiviral treatment and retreatment in United Kingdom–based patients infected with hepatitis C virus genotypes/subtypes endemic in Africa. Journal of Infectious Diseases, 226(6), pp. 995-1004. (doi: 10.1093/infdis/jiab110) (PMID:33668068) (PMCID:PMC9492310)

Bamford, C. G.C., Aranday-Cortes, E. , Sanchez-Velazquez, R., Mullan, C., Kohl, A. , Patel, A. H. , Wilson, S. J. and McLauchlan, J. (2022) A human and rhesus macaque interferon-stimulated gene screen shows that over-expression of ARHGEF3/XPLN inhibits replication of hepatitis C virus and other flavivirids. Viruses, 14(8), 1655. (doi: 10.3390/v14081655) (PMID:36016278) (PMCID:PMC9414520)

Aggarwal, D. et al. (2022) Genomic assessment of quarantine measures to prevent SARS-CoV-2 importation and transmission. Nature Communications, 13, 1012. (doi: 10.1038/s41467-022-28371-z)

Aggarwal, D. et al. (2022) Genomic epidemiology of SARS-CoV-2 in a UK university identifies dynamics of transmission. Nature Communications, 13, 751. (doi: 10.1038/s41467-021-27942-w) (PMID:35136068) (PMCID:PMC8826310)

Bamford, C. G.G. et al. (2022) Comparison of SARS-CoV-2 evolution in paediatric primary airway epithelial cell cultures compared with vero-derived cell lines. Viruses, 14(2), e325. (doi: 10.3390/v14020325) (PMID:35215919) (PMCID:PMC8877208)

Twohig, K. A. et al. (2022) Hospital admission and emergency care attendance risk for SARS-CoV-2 delta (B.1.617.2) compared with alpha (B.1.1.7) variants of concern: a cohort study. Lancet Infectious Diseases, 22(1), pp. 35-42. (doi: 10.1016/S1473-3099(21)00475-8) (PMID:34461056) (PMCID:PMC8397301)

Xu, R. et al. (2022) The evolutionary dynamics and epidemiological history of hepatitis C virus genotype 6, including unique strains from the Li community of Hainan Island, China. Virus Evolution, 8(1), veac012. (doi: 10.1093/ve/veac012) (PMID:35600095) (PMCID:PMC9115904)

2021

Smith, D. A. et al. (2021) Real world SOF/VEL/VOX retreatment outcomes and viral resistance analysis for HCV patients with prior failure to DAA therapy. Journal of Viral Hepatitis, 28(9), pp. 1256-1264. (doi: 10.1111/jvh.13549) (PMID:34003556)

Li, K. K. et al. (2021) Genetic epidemiology of SARS-CoV-2 transmission in renal dialysis units - a high risk community-hospital interface. Journal of Infection, 83(1), pp. 96-103. (doi: 10.1016/j.jinf.2021.04.020) (PMID:33895226) (PMCID:PMC8061788)

Graham, M. S. et al. (2021) Changes in symptomatology, reinfection, and transmissibility associated with the SARS-CoV-2 variant B.1.1.7: an ecological study. Lancet Public Health, 6(5), e335-e345. (doi: 10.1016/S2468-2667(21)00055-4)

Volz, E. et al. (2021) Assessing transmissibility of SARS-CoV-2 lineage B.1.1.7 in England. Nature, 593(7858), pp. 266-269. (doi: 10.1038/s41586-021-03470-x) (PMID:33767447)

Da Silva Filipe, A. et al. (2021) Genomic epidemiology reveals multiple introductions of SARS-CoV-2 from mainland Europe into Scotland. Nature Microbiology, 6(1), pp. 112-122. (doi: 10.1038/s41564-020-00838-z) (PMID:33349681)

Parker, M. D. et al. (2021) Subgenomic RNA identification in SARS-CoV-2 genomic sequencing data. Genome Research, 31, pp. 645-658. (doi: 10.1101/gr.268110.120) (PMID:33722935) (PMCID:PMC8015849)

2019

Ansari, M. A. et al. (2019) Interferon lambda 4 impacts the genetic diversity of hepatitis C virus. eLife, 8, e42463. (doi: 10.7554/eLife.42463) (PMID:31478835) (PMCID:PMC6721795)

Wing, P. A.C. et al. (2019) Amino acid substitutions in genotype 3a hepatitis C virus polymerase protein affect responses to sofosbuvir. Gastroenterology, 157(3), 692-704.e9. (doi: 10.1053/j.gastro.2019.05.007) (PMID:31078622)

Singer, J. B. et al. (2019) Interpreting viral deep sequencing data with GLUE. Viruses, 11(4), 323. (doi: 10.3390/v11040323) (PMID:30987147) (PMCID:PMC6520954)

2018

Bamford, C. G.G. et al. (2018) A polymorphic residue that attenuates the antiviral potential of interferon lambda 4 in hominid lineages. PLoS Pathogens, 14(10), e1007307. (doi: 10.1371/journal.ppat.1007307) (PMID:30308076) (PMCID:PMC6181419)

da Silva Filipe, A. et al. (2018) Reply to: "Reply to: 'Response to DAA therapy in the NHS England Early Access Programme for rare HCV subtypes from low and middle income countries'". Journal of Hepatology, 68(4), pp. 864-866. (doi: 10.1016/j.jhep.2017.11.044) (PMID:29339112)

2017

da Silva Filipe, A. et al. (2017) Response to DAA therapy in the NHS England early access programme for rare HCV subtypes from low and middle income countries. Journal of Hepatology, 67(6), pp. 1348-1350. (doi: 10.1016/j.jhep.2017.06.035) (PMID:28789880)

2015

Robinson, M. W. et al. (2015) Viral genotype correlates with distinct liver gene transcription signatures in chronic hepatitis C virus infection. Liver International, 35(10), pp. 2256-2264. (doi: 10.1111/liv.12830) (PMID:25800823) (PMCID:PMC4949513)

2013

Aranday-Cortes, E. , Bull, N.C., Villarreal-Ramos, B., Gough, J., Hicks, D., Ortiz-Peláez, A., Vordermeier, H.M. and Salguero, F.J. (2013) Upregulation of IL-17A, CXCL9 and CXCL10 in early-stage granulomas induced by Mycobacterium bovis in cattle. Transboundary and Emerging Diseases, 60(6), pp. 525-537. (doi: 10.1111/j.1865-1682.2012.01370.x)

2012

Aranday-Cortes, E. , Hogarth, P. J., Kaveh, D. A., Whelan, A. O., Villarreal-Ramos, B., Lalvani, A. and Vordermeier, H. M. (2012) Transcriptional profiling of disease-induced host responses in bovine tuberculosis and the identification of potential diagnostic biomarkers. PLoS ONE, 7(2), e30626. (doi: 10.1371/journal.pone.0030626)

Bhuju, S., Aranday-Cortes, E. , Villarreal-Ramos, B., Xing, Z., Singh, M. and Vordermeier, H. M. (2012) Global gene transcriptome analysis in vaccinated cattle revealed a dominant role of IL-22 for protection against bovine tuberculosis. PLoS Pathogens, 8(12), e1003077. (doi: 10.1371/journal.ppat.1003077)

2010

Aranday-Cortes, E. , Kaveh, D., Nunez-Garcia, J., Hogarth, P. J. and Vordermeier, H. M. (2010) Mycobacterium bovis-BCG vaccination induces specific pulmonary transcriptome biosignatures in mice. PLoS ONE, 5(6), e11319. 20596522. (doi: 10.1371/journal.pone.0011319) (PMID:PMC2893133)

This list was generated on Thu Jun 8 10:03:01 2023 BST.
Jump to: Articles
Number of items: 24.

Articles

Aranday-Cortes, E. et al. (2022) Real-world outcomes of direct-acting antiviral treatment and retreatment in United Kingdom–based patients infected with hepatitis C virus genotypes/subtypes endemic in Africa. Journal of Infectious Diseases, 226(6), pp. 995-1004. (doi: 10.1093/infdis/jiab110) (PMID:33668068) (PMCID:PMC9492310)

Bamford, C. G.C., Aranday-Cortes, E. , Sanchez-Velazquez, R., Mullan, C., Kohl, A. , Patel, A. H. , Wilson, S. J. and McLauchlan, J. (2022) A human and rhesus macaque interferon-stimulated gene screen shows that over-expression of ARHGEF3/XPLN inhibits replication of hepatitis C virus and other flavivirids. Viruses, 14(8), 1655. (doi: 10.3390/v14081655) (PMID:36016278) (PMCID:PMC9414520)

Aggarwal, D. et al. (2022) Genomic assessment of quarantine measures to prevent SARS-CoV-2 importation and transmission. Nature Communications, 13, 1012. (doi: 10.1038/s41467-022-28371-z)

Aggarwal, D. et al. (2022) Genomic epidemiology of SARS-CoV-2 in a UK university identifies dynamics of transmission. Nature Communications, 13, 751. (doi: 10.1038/s41467-021-27942-w) (PMID:35136068) (PMCID:PMC8826310)

Bamford, C. G.G. et al. (2022) Comparison of SARS-CoV-2 evolution in paediatric primary airway epithelial cell cultures compared with vero-derived cell lines. Viruses, 14(2), e325. (doi: 10.3390/v14020325) (PMID:35215919) (PMCID:PMC8877208)

Twohig, K. A. et al. (2022) Hospital admission and emergency care attendance risk for SARS-CoV-2 delta (B.1.617.2) compared with alpha (B.1.1.7) variants of concern: a cohort study. Lancet Infectious Diseases, 22(1), pp. 35-42. (doi: 10.1016/S1473-3099(21)00475-8) (PMID:34461056) (PMCID:PMC8397301)

Xu, R. et al. (2022) The evolutionary dynamics and epidemiological history of hepatitis C virus genotype 6, including unique strains from the Li community of Hainan Island, China. Virus Evolution, 8(1), veac012. (doi: 10.1093/ve/veac012) (PMID:35600095) (PMCID:PMC9115904)

Smith, D. A. et al. (2021) Real world SOF/VEL/VOX retreatment outcomes and viral resistance analysis for HCV patients with prior failure to DAA therapy. Journal of Viral Hepatitis, 28(9), pp. 1256-1264. (doi: 10.1111/jvh.13549) (PMID:34003556)

Li, K. K. et al. (2021) Genetic epidemiology of SARS-CoV-2 transmission in renal dialysis units - a high risk community-hospital interface. Journal of Infection, 83(1), pp. 96-103. (doi: 10.1016/j.jinf.2021.04.020) (PMID:33895226) (PMCID:PMC8061788)

Graham, M. S. et al. (2021) Changes in symptomatology, reinfection, and transmissibility associated with the SARS-CoV-2 variant B.1.1.7: an ecological study. Lancet Public Health, 6(5), e335-e345. (doi: 10.1016/S2468-2667(21)00055-4)

Volz, E. et al. (2021) Assessing transmissibility of SARS-CoV-2 lineage B.1.1.7 in England. Nature, 593(7858), pp. 266-269. (doi: 10.1038/s41586-021-03470-x) (PMID:33767447)

Da Silva Filipe, A. et al. (2021) Genomic epidemiology reveals multiple introductions of SARS-CoV-2 from mainland Europe into Scotland. Nature Microbiology, 6(1), pp. 112-122. (doi: 10.1038/s41564-020-00838-z) (PMID:33349681)

Parker, M. D. et al. (2021) Subgenomic RNA identification in SARS-CoV-2 genomic sequencing data. Genome Research, 31, pp. 645-658. (doi: 10.1101/gr.268110.120) (PMID:33722935) (PMCID:PMC8015849)

Ansari, M. A. et al. (2019) Interferon lambda 4 impacts the genetic diversity of hepatitis C virus. eLife, 8, e42463. (doi: 10.7554/eLife.42463) (PMID:31478835) (PMCID:PMC6721795)

Wing, P. A.C. et al. (2019) Amino acid substitutions in genotype 3a hepatitis C virus polymerase protein affect responses to sofosbuvir. Gastroenterology, 157(3), 692-704.e9. (doi: 10.1053/j.gastro.2019.05.007) (PMID:31078622)

Singer, J. B. et al. (2019) Interpreting viral deep sequencing data with GLUE. Viruses, 11(4), 323. (doi: 10.3390/v11040323) (PMID:30987147) (PMCID:PMC6520954)

Bamford, C. G.G. et al. (2018) A polymorphic residue that attenuates the antiviral potential of interferon lambda 4 in hominid lineages. PLoS Pathogens, 14(10), e1007307. (doi: 10.1371/journal.ppat.1007307) (PMID:30308076) (PMCID:PMC6181419)

da Silva Filipe, A. et al. (2018) Reply to: "Reply to: 'Response to DAA therapy in the NHS England Early Access Programme for rare HCV subtypes from low and middle income countries'". Journal of Hepatology, 68(4), pp. 864-866. (doi: 10.1016/j.jhep.2017.11.044) (PMID:29339112)

da Silva Filipe, A. et al. (2017) Response to DAA therapy in the NHS England early access programme for rare HCV subtypes from low and middle income countries. Journal of Hepatology, 67(6), pp. 1348-1350. (doi: 10.1016/j.jhep.2017.06.035) (PMID:28789880)

Robinson, M. W. et al. (2015) Viral genotype correlates with distinct liver gene transcription signatures in chronic hepatitis C virus infection. Liver International, 35(10), pp. 2256-2264. (doi: 10.1111/liv.12830) (PMID:25800823) (PMCID:PMC4949513)

Aranday-Cortes, E. , Bull, N.C., Villarreal-Ramos, B., Gough, J., Hicks, D., Ortiz-Peláez, A., Vordermeier, H.M. and Salguero, F.J. (2013) Upregulation of IL-17A, CXCL9 and CXCL10 in early-stage granulomas induced by Mycobacterium bovis in cattle. Transboundary and Emerging Diseases, 60(6), pp. 525-537. (doi: 10.1111/j.1865-1682.2012.01370.x)

Aranday-Cortes, E. , Hogarth, P. J., Kaveh, D. A., Whelan, A. O., Villarreal-Ramos, B., Lalvani, A. and Vordermeier, H. M. (2012) Transcriptional profiling of disease-induced host responses in bovine tuberculosis and the identification of potential diagnostic biomarkers. PLoS ONE, 7(2), e30626. (doi: 10.1371/journal.pone.0030626)

Bhuju, S., Aranday-Cortes, E. , Villarreal-Ramos, B., Xing, Z., Singh, M. and Vordermeier, H. M. (2012) Global gene transcriptome analysis in vaccinated cattle revealed a dominant role of IL-22 for protection against bovine tuberculosis. PLoS Pathogens, 8(12), e1003077. (doi: 10.1371/journal.ppat.1003077)

Aranday-Cortes, E. , Kaveh, D., Nunez-Garcia, J., Hogarth, P. J. and Vordermeier, H. M. (2010) Mycobacterium bovis-BCG vaccination induces specific pulmonary transcriptome biosignatures in mice. PLoS ONE, 5(6), e11319. 20596522. (doi: 10.1371/journal.pone.0011319) (PMID:PMC2893133)

This list was generated on Thu Jun 8 10:03:01 2023 BST.