Data collected
The four page questionnaire used for the Main & Tiree Studies was similar to that used for the original Whitehall study, both being developed at around the same time. Subjects completed the appropriate box, answers were coded and later entered onto computer anonymously. The original questionnaires are currently stored at the Glasgow University Archive.
Data recorded
- Questionnaire data
sex
occupation
employment status
date of birth
place of birth (coded by population size)
marital status
height (self reported)
weight (self reported)
detailed questions on smoking habit
exercise activity
car ownership
sleep
daily consumptions of milk, coffee, tea
alcohol intake
MRC bronchitis
chest wheeze
weather effect on breathing
Rose angina questionnaire
severe chest pain
intermittent claudication
diabetes
partner suffer from bronchitis or heart trouble - Clinical measurements:
respiratory function, FEV1, MMF, FVC
blood pressure
chest x-ray
ECG
biochemical tests on urine: blood*, glucose*, protein*, pH
triceps skinfold thickness
* only available on some subjects - Derived data:
cardiothoracic ratio - Follow-up data:
mortality
Further visits
Between 1967 and 1969 participants were invited to take part in a repeat survey. The format of this was identical to the previous one.
Participants in the Collaborative study completed a questionnaire of personal details and health questions prior to attending a clinical examination. These answers were checked by experienced interviewers at the time of attending. Clinical measurements were recorded by staff at the clinic or later upon receipt of laboratory results of samples taken. The data were subsequently coded and entered onto computer. Mortality incidence has also been recorded. The original questionnaires are currently stored at the Glasgow University Archive.
Data recorded
- Questionnaire data
sex
occupation, employment status
date of birth, place of birth (category), type of place where lived longest
marital status
MRC bronchitis questionnaire
chest wheeze
weather affecting breathing
exercise
regular car driver
sleep
daily consumption of milk, tea, coffee
addition of sugar
alcohol consumption per week
detailed questions on smoking habit
Rose angina questionnaire
severe chest pain
intermittent claudication
diabetes
parent's cause of death
partner suffer from bronchitis or heart condition
first regular occupation
father's occupation
Reeder Stress Inventory
job satisfaction
numbers of siblings, position in family
number of job changes
most recent job change
age completed full-time education - Clinical measurements
respiratory function, FEV1, MMF, FVC
chest X-ray
blood pressure
triceps skinfold thickness medical history
ECG (Minnesota code)
biochemical analyses of urine specimum: blood, ketones, glucose, protein, pH
cholesterol (plasma)
triglycerides
height
weight
tuberculin Tine test
lipoprotein phenotype - Derived data
age at screening
father’s social class, own 1st social class, own social class
Carstairs deprivation score/category
body mass index
%-predicted FEV1
Rose angina classification
ischaemia on ECG - Follow-up data
mortality
cancer incidence
hospital admissions
Further visits
A further visit six weeks later was arranged for participants whose clinical measurements required confirmation or clarification. The data were recorded on computer.
Subjects were invited for further screening in 1977. Those who attended completed the same questionnaire as previously and underwent a similar series of tests. The second screening data were also recorded on computer.
The questionnaire used in the Renfrew/Paisley study was very similar in appearance to that used in the Collaborative study but some new questions were included and others (eg. diet and early life) omitted. The data have been coded and entered onto computer, anonymously. Mortality incidence has also been recorded. The original questionnaires are currently stored at the Glasgow University Archive.
Data recorded
- Questionnaire data
sex
marital status
date of birth
occupation
exercise
MRC bronchitis
chest wheeze
weather effect on breathing
detailed questions on smoking habit
Rose angina questionnaire
severe chest pain
diabetes
stroke symptoms
treatment for blood pressure
asthma / hayfever
years in present home (Paisley only) - Clinical measurements
blood pressure
chest X-ray
Tine test
sputum
cholesterol (plasma)
blood sugar*
cardiothoracic ratio
height
weight
ECG (Minnesota code)
respiratory function, FEV1, FVC
biochemical tests*: Sodium (Renfrew only), potassium, O2, Hb, carboxyhaemoglobin
* only available on some subjects - Derived data
age at screening
Occupational social class
Carstairs deprivation score/category
body mass index
%-predicted FEV1
Rose angina classification
ischaemia on ECG - Follow-up data
mortality
cancer incidence
hospital admissions
Further visits
A further visit six weeks later was arranged for participants whose clinical measurements required confirmation or clarification. These data were recorded on computer.
Subjects were invited for further screening approximately 4 years later. Those who attended completed the same questionnaire as previously and underwent a similar series of tests. These second screening data were also recorded on computer.
Periodically throughout the duration of screening additional studies were undertaken on some subjects and the results summarised and recorded on the relevant questionnaire:
General Health questionnaire
Supplement of smoking and diet
Offspring who had two parents who had participated in the original Renfrew/Paisley study and were themselves between the age of 30-59 and living locally were invited to take part in the Family Study. Participants were asked to complete a 33 page health and lifestyle questionnaire at home and later attend a clinic for physical examination. The original questionnaires are currently stored at Glasgow University Archive.
Data recorded
- Questionnaire data
personal: gender, date of birth, marital status, education, occupation, employment, housing tenure, accommodation, car ownership, food frequency questionnaire, physical activity, smoking habit, exposure to passive smoking
medical history:limiting long-standing illness, doctor diagnosed illness (angina, heart attack, stroke, high blood pressure, diabetes, high cholesterol, asthma, bronchitis/emphysema, venous thrombo-embolism, lung cancer, breast cancer, stomach/bowel cancer), medication (incl. high blood pressure, cholesterol, aspirin, vitamins/supplements), Rose angina questionnaire, European Community Respiratory Health Survey, MRC bronchitis questionnaire, intermittent claudication, allergic symptoms
women only: menstruation, pregnancy, use of contraception, HRT
family history: parents, siblings
childhood circumstances
vehicle access, housing tenure, accommodation, parental smoking, paternal occupation
birthweight, place of birth, infant feeding, respiratory illness in early life (based on reported parent's response)
health beliefs/attitudes, behavioural changes - Clinical measurements
blood pressure, pulse, MAP
height
sitting height
weight
waist & hip circumference
spirometry
ECG - Laboratory tests
sodium, potassium, chlorine, bicarbonate, urea, creatinine, glucose (non-fasting)
bilirubin, AsT, AlT, alk phosphate, adj calcium, calcium, phospate, proteins, albumin, globulins, urate, Gamma GT
cholesterol (non-fasting), triglycerides, HDL
haematocrit, white cell count, plasma viscosity, factor VII, factor VIII, factor IX, APTT, APC resistance, fibrinogen, von Willebrand factor, t-PA, PAI, D-dimer
vitamins A, C, E
lutein, lycopene, a-carotene, b-carotene, cryptozan, C-reactive protein, cotinine
Lp(a), Apo(a) phenotype
ACE genotype - Stored samples
serum
plasma
DNA - Derived data
age at screening
occupational social class, Carstairs deprivation score/category
family size, birth order
body mass index, waist/hip ratio, leg length, trunk height
duration/pack years of smoking
weekly alcohol intake (beer, wine, spirits, total)
Rose angina classification
whole blood viscosity
daily nutrient intakes
fat, saturated/polyunsaturated fat, protein, carbohydrate, starch, sugar, fibre, energy, cholesterol, vitamin C, retinal, carotene, tocop, linol, iron
% food energy derived from fat
ECG evidence of previous myocardial infarction/ischaemia
ECG evidence of left ventricular hypertrophy
%-predicted FEV1
hormone replacement; route of administration, hormones, duration
oral contraceptives; hormones, oestrogen dose, 3rd generation - Follow-up data
mortality
cancer incidence
hospital admissions
Further visits
Between 2001-2003 the TWOGen study undertook the collecting of blood samples from the surviving parents.