Dr Vladimira Moulisova

  • Affiliate (School of Engineering)

telephone: 01413304901
email: Vladimira.Moulisova@glasgow.ac.uk

Research interests

I work as a Research Associate in the MiMe group at the Biomedical Engineering Research Division of the School of Engineering. I have a Master Degree in Biochemistry from the Charles University in Prague, and I obtained a PhD in Molecular and Cell Biology at the University of South Bohemia (Czech Republic) in 2006. Before joining the School or Engineering in 2013, I spent 6 years doing research at the School of Medical, Veterinary and Life Sciences at the University of Glasgow.

My current research interest is focused on vascularization processes applicable in tissue engineering and regenerative medicine. Although there have been significant advances in engineering tissues for transplantation (e.g. bone, muscle or neural grafts), vascularization of such tissues is still a challenge. Deeper knowledge about vessel formation and regeneration, particularly related to new biocompatible materials, is necessary for development of suitable transplants. Rather than preparing a pre-vascularized graft, I study synthetic biomaterials that can stimulate natural revascularization in situ using only specific proteins of extracellular matrix and very low concentrations of growth factors. For many applications, this simplified platform would be not only cheaper and more robust than a fully grown tissue graft but would also enable the implanted system to help the organism to self-repair. I am also currently collaborating with Polytechnic University of Valencia on the regenerative processes of cartilage.

My previous research has spanned several topics, from mechanisms of chemical carcinogenesis and the role CYPs across hepatocyte membrane transport and oxidative damage to mechanisms of aging and regenerative effect of microvesicles isolated from stem cells.


Supervision

Co-supervision of PhD students:

  • Nadira Salah (Regeneration of epithelial tissues: Reconstructing bronchial and fallopian tube mucosae; expected 2018)

Lab supervision of MSc students:

  • Jake Hay (The interaction of genetically modified lactococcus lactis with nanotopography to modulate cell differentiation; 2014)
  • Mohammed Al-Jarsha (In vitro investigation of a new biomaterial coating for titanium implants incorporating rhBMP-7; 2015)

Lab supervision of BSc students:

  • Aisha Abdullahi (Biomaterials for vascularization: Endothelial cell focal adhesions study; 2015)

Publications

List by: Type | Date

Jump to: 2018 | 2017 | 2016 | 2015 | 2012 | 2009 | 2008 | 2006
Number of items: 17.

2018

Rico, P., Rodrigo-Navarro, A. , De la Pena, M., Moulisova, V., Costell, M. and Salmeron-Sanchez, M. (2018) Simultaneous boron ion-channel/growth factor receptor activation for enhanced vascularization. Advanced Biosystems, (Accepted for Publication)

Moulisova, V., Al-Jarsha, M., Leal-Egaña, A., Connell, A., Naudi, K. B., Ayoub, A. F. , Dalby, M. J. and Salmeron-Sanchez, M. (2018) Engineered coatings for titanium implants to present ultralow doses of BMP-7. ACS Biomaterials Science and Engineering, 4(5), pp. 1812-1819. (doi:10.1021/acsbiomaterials.7b01037) (PMID:29862317) (PMCID:PMC5973637)

2017

Moulisová, V., Poveda-Reyes, S., Sanmartín-Masiá, E., Quintanilla-Sierra, L., Salmeron-Sanchez, M. and Gallego Ferrer, G. (2017) Hybrid protein-glycosaminoglycan hydrogels promote chondrogenic stem cell differentiation. ACS Omega, 2(11), pp. 7609-7620. (doi:10.1021/acsomega.7b01303)

Cantini, M. , Gomide, K., Moulisova, V., González-García, C. and Salmerón-Sánchez, M. (2017) Vitronectin as a micromanager of cell response in material-driven fibronectin nanonetworks. Advanced Biosystems, 1(9), 1700047. (doi:10.1002/adbi.201700047) (PMID:29497701) (PMCID:PMC5822048)

Moulisová, V., Gonzalez-Garcia, C., Cantini, M. , Rodrigo-Navarro, A. , Weaver, J., Costell, M., Sabater i Serra, R., Dalby, M. J. , García, A. J. and Salmerón-Sánchez, M. (2017) Engineered microenvironments for synergistic VEGF - integrin signalling during vascularization. Biomaterials, 126, pp. 61-74. (doi:10.1016/j.biomaterials.2017.02.024) (PMID:28279265) (PMCID:PMC5354119)

2016

Poveda-Reyes, S., Moulisova, V., Sanmartín-Masiá, E., Quintanilla-Sierra, L., Salmeron-Sanchez, M. and Gallego Ferrer, G. (2016) Gelatin-hyaluronic acid hydrogels with tuned stiffness to counterbalance cellular forces and promote cell differentiation. Macromolecular Bioscience, 16(9), pp. 1311-1324. (doi:10.1002/mabi.201500469) (PMID:27213762)

McGuinness, D., Anthony, D. F., Moulisova, V., MacDonald, A. I., Macintyre, A., Thomson, J., Nag, A., Davies, R. W. and Shiels, P. G. (2016) Microvesicles but not exosomes from Pathfinder Cells stimulate functional recovery of the pancreas in a mouse streptozotocin-induced diabetes model. Rejuvenation Research, 19(3), pp. 223-232. (doi:10.1089/rej.2015.1723)

Hay, J. , Rodrigo-Navarro, A. , Hassi, K., Moulisova, V., Dalby, M. J. and Salmeron-Sanchez, M. (2016) Living biointerfaces based on non-pathogenic bacteria support stem cell differentiation. Scientific Reports, 6, 21809. (doi:10.1038/srep21809) (PMID:26902619) (PMCID:PMC4763179)

2015

Koblížek, M., Moulisová, V., Muroňová, M. and Oborník, M. (2015) Horizontal transfers of two types of puf operons among phototrophic members of the Roseobacter clade. Folia Microbiologica, 60(1), pp. 37-43. (doi:10.1007/s12223-014-0337-z) (PMID:25090942)

2012

Luer, L., Moulisova, V., Henry, S., Polli, D., Brotosudarmo, T.H.P., Hoseinkhani, S., Brida, D., Lanzani, G., Cerullo, G. and Cogdell, R.J. (2012) Tracking energy transfer between light harvesting complex 2 and 1 in photosynthetic membranes grown under high and low illumination. Proceedings of the National Academy of Sciences of the United States of America, 109(5), pp. 1473-1478. (doi:10.1073/pnas.1113080109)

Roszak, A.W., Moulisova, V., Reksodipuro, A.D.P., Gardiner, A.T., Fujii, R., Hashimoto, H., Isaacs, N.W. and Cogdell, R.J. (2012) New insights into the structure of the reaction centre from Blastochloris viridis: evolution in the laboratory. Biochemical Journal, 442(1), pp. 27-37. (doi:10.1042/BJ20111540)

2009

Moulisova, V., Luer, L., Hoseinkhani, S., Brotosudarmo, T.H.P., Collins, A.M., Lanzani, G., Blankenship, R.E. and Cogdell, R.J. (2009) Low light adaptation: energy transfer processes in different types of light harvesting complexes from Rhodopseudomonas palustris. Biophysical Journal, 97(11), pp. 3019-3028. (doi:10.1016/j.bpj.2009.09.023)

Brotosudarmo, T.H.P., Kunz, R., Bohm, P., Gardiner, A.T., Moulisova, V., Cogdell, R.J. and Kohler, J. (2009) Single-molecule spectroscopy reveals that individual low-light lh2 complexes from Rhodopseudomonas palustris 2.1.6. have a heterogeneous polypeptide composition. Biophysical Journal, 97(5), pp. 1491-1500. (doi:10.1016/j.bpj.2009.06.034) (PMID:19720038) (PMCID:PMC2749768)

2008

Salka, I., Moulisová, V., Koblízek, M., Jost, G., Jürgens, K. and Labrenz, M. (2008) Abundance, depth distribution, and composition of aerobic bacteriochlorophyll a-producing bacteria in four basins of the central Baltic Sea. Applied and Environmental Microbiology, 74(14), pp. 4398-4404. (doi:10.1128/AEM.02447-07) (PMID:18502937) (PMCID:PMC2493182)

2006

Masín, M., Zdun, A., Stón-Egiert, J., Nausch, M., Labrenz, M., Moulisová, V. and Koblízek, M. (2006) Seasonal changes and diversity of aerobic anoxygenic phototrophs in the Baltic Sea. Aquatic Microbial Ecology, 45, pp. 247-254. (doi:10.3354/ame045247)

Moulisová, V., Srbová, M., Jedlicková, O., Šebestian, J. and Jegorov, A. (2006) Silybin reduces lipid peroxidation of rat hepatocyte membrane caused by cyclosporin A. Biochemistry (Moscow), 71(10), pp. 1110-1114. (doi:10.1134/S0006297906100087) (PMID:17125459)

Moulisova, V., Sebestian, J., Jedlickova, O., Jegorov, A. and Sebestianova, S. (2006) Replacement of cyclosporin A from its binding to hepatocyte plasma membrane by silymarin flavonoids. Letters in Drug Design and Discovery, 3(6), pp. 429-435. (doi:10.2174/157018006777805567)

This list was generated on Sun Dec 16 10:53:03 2018 GMT.
Jump to: Articles
Number of items: 17.

Articles

Rico, P., Rodrigo-Navarro, A. , De la Pena, M., Moulisova, V., Costell, M. and Salmeron-Sanchez, M. (2018) Simultaneous boron ion-channel/growth factor receptor activation for enhanced vascularization. Advanced Biosystems, (Accepted for Publication)

Moulisova, V., Al-Jarsha, M., Leal-Egaña, A., Connell, A., Naudi, K. B., Ayoub, A. F. , Dalby, M. J. and Salmeron-Sanchez, M. (2018) Engineered coatings for titanium implants to present ultralow doses of BMP-7. ACS Biomaterials Science and Engineering, 4(5), pp. 1812-1819. (doi:10.1021/acsbiomaterials.7b01037) (PMID:29862317) (PMCID:PMC5973637)

Moulisová, V., Poveda-Reyes, S., Sanmartín-Masiá, E., Quintanilla-Sierra, L., Salmeron-Sanchez, M. and Gallego Ferrer, G. (2017) Hybrid protein-glycosaminoglycan hydrogels promote chondrogenic stem cell differentiation. ACS Omega, 2(11), pp. 7609-7620. (doi:10.1021/acsomega.7b01303)

Cantini, M. , Gomide, K., Moulisova, V., González-García, C. and Salmerón-Sánchez, M. (2017) Vitronectin as a micromanager of cell response in material-driven fibronectin nanonetworks. Advanced Biosystems, 1(9), 1700047. (doi:10.1002/adbi.201700047) (PMID:29497701) (PMCID:PMC5822048)

Moulisová, V., Gonzalez-Garcia, C., Cantini, M. , Rodrigo-Navarro, A. , Weaver, J., Costell, M., Sabater i Serra, R., Dalby, M. J. , García, A. J. and Salmerón-Sánchez, M. (2017) Engineered microenvironments for synergistic VEGF - integrin signalling during vascularization. Biomaterials, 126, pp. 61-74. (doi:10.1016/j.biomaterials.2017.02.024) (PMID:28279265) (PMCID:PMC5354119)

Poveda-Reyes, S., Moulisova, V., Sanmartín-Masiá, E., Quintanilla-Sierra, L., Salmeron-Sanchez, M. and Gallego Ferrer, G. (2016) Gelatin-hyaluronic acid hydrogels with tuned stiffness to counterbalance cellular forces and promote cell differentiation. Macromolecular Bioscience, 16(9), pp. 1311-1324. (doi:10.1002/mabi.201500469) (PMID:27213762)

McGuinness, D., Anthony, D. F., Moulisova, V., MacDonald, A. I., Macintyre, A., Thomson, J., Nag, A., Davies, R. W. and Shiels, P. G. (2016) Microvesicles but not exosomes from Pathfinder Cells stimulate functional recovery of the pancreas in a mouse streptozotocin-induced diabetes model. Rejuvenation Research, 19(3), pp. 223-232. (doi:10.1089/rej.2015.1723)

Hay, J. , Rodrigo-Navarro, A. , Hassi, K., Moulisova, V., Dalby, M. J. and Salmeron-Sanchez, M. (2016) Living biointerfaces based on non-pathogenic bacteria support stem cell differentiation. Scientific Reports, 6, 21809. (doi:10.1038/srep21809) (PMID:26902619) (PMCID:PMC4763179)

Koblížek, M., Moulisová, V., Muroňová, M. and Oborník, M. (2015) Horizontal transfers of two types of puf operons among phototrophic members of the Roseobacter clade. Folia Microbiologica, 60(1), pp. 37-43. (doi:10.1007/s12223-014-0337-z) (PMID:25090942)

Luer, L., Moulisova, V., Henry, S., Polli, D., Brotosudarmo, T.H.P., Hoseinkhani, S., Brida, D., Lanzani, G., Cerullo, G. and Cogdell, R.J. (2012) Tracking energy transfer between light harvesting complex 2 and 1 in photosynthetic membranes grown under high and low illumination. Proceedings of the National Academy of Sciences of the United States of America, 109(5), pp. 1473-1478. (doi:10.1073/pnas.1113080109)

Roszak, A.W., Moulisova, V., Reksodipuro, A.D.P., Gardiner, A.T., Fujii, R., Hashimoto, H., Isaacs, N.W. and Cogdell, R.J. (2012) New insights into the structure of the reaction centre from Blastochloris viridis: evolution in the laboratory. Biochemical Journal, 442(1), pp. 27-37. (doi:10.1042/BJ20111540)

Moulisova, V., Luer, L., Hoseinkhani, S., Brotosudarmo, T.H.P., Collins, A.M., Lanzani, G., Blankenship, R.E. and Cogdell, R.J. (2009) Low light adaptation: energy transfer processes in different types of light harvesting complexes from Rhodopseudomonas palustris. Biophysical Journal, 97(11), pp. 3019-3028. (doi:10.1016/j.bpj.2009.09.023)

Brotosudarmo, T.H.P., Kunz, R., Bohm, P., Gardiner, A.T., Moulisova, V., Cogdell, R.J. and Kohler, J. (2009) Single-molecule spectroscopy reveals that individual low-light lh2 complexes from Rhodopseudomonas palustris 2.1.6. have a heterogeneous polypeptide composition. Biophysical Journal, 97(5), pp. 1491-1500. (doi:10.1016/j.bpj.2009.06.034) (PMID:19720038) (PMCID:PMC2749768)

Salka, I., Moulisová, V., Koblízek, M., Jost, G., Jürgens, K. and Labrenz, M. (2008) Abundance, depth distribution, and composition of aerobic bacteriochlorophyll a-producing bacteria in four basins of the central Baltic Sea. Applied and Environmental Microbiology, 74(14), pp. 4398-4404. (doi:10.1128/AEM.02447-07) (PMID:18502937) (PMCID:PMC2493182)

Masín, M., Zdun, A., Stón-Egiert, J., Nausch, M., Labrenz, M., Moulisová, V. and Koblízek, M. (2006) Seasonal changes and diversity of aerobic anoxygenic phototrophs in the Baltic Sea. Aquatic Microbial Ecology, 45, pp. 247-254. (doi:10.3354/ame045247)

Moulisová, V., Srbová, M., Jedlicková, O., Šebestian, J. and Jegorov, A. (2006) Silybin reduces lipid peroxidation of rat hepatocyte membrane caused by cyclosporin A. Biochemistry (Moscow), 71(10), pp. 1110-1114. (doi:10.1134/S0006297906100087) (PMID:17125459)

Moulisova, V., Sebestian, J., Jedlickova, O., Jegorov, A. and Sebestianova, S. (2006) Replacement of cyclosporin A from its binding to hepatocyte plasma membrane by silymarin flavonoids. Letters in Drug Design and Discovery, 3(6), pp. 429-435. (doi:10.2174/157018006777805567)

This list was generated on Sun Dec 16 10:53:03 2018 GMT.